A kind of compound Chinese herb formula of anti-chicken high temperature heat stress and its application
Technical field
The present invention relates in animal compound Chinese medicine preparation technical field, more particularly to a kind of compound of anti-chicken high temperature heat stress
Herb formulation and its application, the Chinese herbal medicine formula are applied to preventing and treating laying hen and broiler chicken physiological responses to heat stress.
Background technology
Heat stress refer to because hot environment and caused by laying hen, the reduction of broiler chicken feed intake, production performance decline, dead mortality
The syndrome of rising.When temperature is more than 25 DEG C, heat stress will occur for chicken, and temperature is higher, stress degree it is bigger.It is lasting to exist
Heat stress harm laying hen and broiler breeding industry, cause chicken to be mined massively appetite declines, laying rate declines, dead mortality increase, pipe
The increase of reason difficulty, economic benefit decline to a great extent.In extreme circumstances, feed intake fall is up to 20%, under laying rate of laying hen
Range of decrease degree is up to 50%, and the death rate of broiler chicken is up to 5-30%.
Usually through strengthening physics cooling measure and improving feeding management in production practices, particularly change feed nutrition dense
The method of degree, conversion feeding time plus soiling, the heat stress for alleviating chicken, this kind of method specificity is not strong, and effect is not
It is very preferable, and add management difficulty.Using vitamin and electrolyte make an addition to feed or drinking-water in, support the use wet curtain add it is logical
The method of wind cooling carries out hen house cooling, but is difficult to when temperature is more than 30 DEG C to gather effect.
The heat stress of chicken is controlled using Chinese herbal medicine formula, caused by more thoroughly solving laying hen, broiler chicken heat stress
Negative effect, efficiently and effectively improves breeding layer chicken benefit, is that Implement Green Food production lays a good foundation with consumption.This
Compound Chinese herb formula embodied in clinical practice action effect substantially, acting duration length, Small side effects, economic benefit
High the characteristics of, be safe, green, efficient Chinese herbal medicine formula.
The content of the invention
For the deficiencies in the prior art, the present invention is intended to provide a kind of compound Chinese herb of anti-chicken high temperature heat stress
Formula and its apply, by selecting suitable medicinal material and its proportioning and formulating the preparation method of its patent medicine, reach safely and effectively
Alleviate the effect of the negative effect of laying hen and broiler chicken heat stress, and it is applied to clinically popularization and application.
In order to achieve the above object, the present invention uses following technical scheme:
A kind of compound Chinese herb formula of anti-chicken high temperature heat stress, is prepared from by following seven tastes Chinese medicine:
Wrinkled giant hyssop, pungent, tepor.Enter spleen, stomach, lung channel.With removing dampness by means of aromatics, relieving pain by regulating middle-JIAO, inducing diaphoresis is evil, except effect of humidity hysteresis.
For wet essential resistance of turbid, the spleen being blocked by dampness, the tripe distention and fullness in the abdomen of transporting imbalance, few food, burnout disease.Table can also be dissipated evil, for treating
Catch a cold and accompany the syndrome of humidity hysteresis.Pharmacological research confirms that the aromatic odor of wrinkled giant hyssop, which has, promotes gastric secretion to make with digestant
With.
Mulberry leaf, it is bitter, sweet, cold.Enter lung, Liver Channel.There is wind-dispelling heat-dissipating, clear liver and improve vision.For treating table in wind-heat
With let out lung heat, effective is demonstrate,proved to affection of exogenous wind-heat etc..Pharmacological research confirms that mulberry leaf have antipyretic, Eradicates phlegm, diuresis, to alleviating heat
The discomfort that stress be caused has positive role.
Eupatorium, it is pungent, flat.Enter the spleen channel.With dampness elimination of being amusing, effect that relieving summer-heat promotes the production of body fluid.It is strongly fragrant in middle burnt institute for damp and hot turbid pathogenic factor
Tripe distention and fullness in the abdomen, white and greasy fur and the summer-heat and damp exterior syndrome of cause.Also it is apt to solution hot summer weather and promotes the production of body fluid, for accumulates in hot summer weather, the syndrome of tripe distention and fullness in the abdomen.
Pharmacological research confirms that eupatorium plays the role of to promote digestive juice secretion, and few food has product caused by the heat stress of chicken is caused to hot summer weather
The mitigation of pole.
Elscholtiza, pungent, tepor.Enter lung, spleen, stomach.There is sweating relieving summer-heat, dispelling dampness and promoting diuresis.Heatstroke for horse, ox
Treatment.Pharmacological research confirms that elscholtiza has sweating, antipyretic, diuresis.
Sweet wormwood, it is bitter, cold.Enter liver, gallbladder channel.With clearing away summerheat, effect of reducing the asthenic fever.Sweet wormwood fragrant odour, though sweetness and bitterness is cold
Without the impairment of the spleen, and there are removing summer-heat summer-heat evil, clearing heat and eliminating dampness, the disease for treating diseases caused by external factors hot summer weather.
Gypsum, pungent, sweet, Great Cold.Enter lung, stomach.Acted on powerful clearing heat-fire, be apt to clear qi leel real heat.For
The big heat of lung stomach, the real heat such as hyperpyrexia is high to contain card.Pharmacological research confirms that gypsum can suppress heating maincenter and play refrigeration function.
The bighead atractylodes rhizome, sweet, bitter, temperature.Enter spleen, stomach.Have effects that to invigorate the spleen and benefit qi, eliminate dampness and have diuretic effect, strengthening exterior and reducing sweat.For taste
Deficiency of food turgor, lassitude hypodynamia caused by the deficiency of vital energy, dysfunction of the spleen in transportation and transformation etc..Pharmacological research confirms that the bighead atractylodes rhizome contains Main Ingredients and Appearance in volatile oil, oil
For atractylol and atractylone, and containing vitamin A sample material, to promoting gastrointestinal peristalsis to have positive role.
The compound Chinese herb formula of the anti-chicken high temperature heat stress, is made up of the traditional Chinese medicinal material raw materials of following weight percent content:
It is preferred that, the compound Chinese herb formula of the anti-chicken high temperature heat stress, by the Chinese medicine of following weight percent content
Material raw material is made:
Optimal, the compound Chinese herb formula of the anti-chicken high temperature heat stress, by the Chinese medicine of following weight percent content
Material raw material is made:
The step of preparation method of the compound Chinese herb of the above-mentioned anti-chicken high temperature heat stress being respectively formulated, is as follows:
Each Chinese medicine is weighed, and size-reduced machine is crushed respectively, each Chinese medicine is mixed by the formula rate after crossing 80 mesh sieves,
It is sealed in standby in the polybag of good airproof performance.
Technical solution of the present invention is to each ingredient requirement:The water content of each raw materials of traditional Chinese medicinal materials is less than 12%, impurity content
Less than 0.5%.
The present invention is according to Chinese veterinarian's medicine theory, with reference to Chinese herbal medicine meridian distribution of property and flavor and efficacy effect feature, correct dialectical
Laying hen and broiler chicken are in the case of based on the pathogenesis of the heat stress caused by high ambient temperature, with the original of Chinese veterinarian's prescription prescription
Then with method, according to the rigorous formula such as monarch, minister, the relation helped, made, seven feelings compatibilities, make its division of labor clearly, Each performs its own functions;Simultaneously
Screen a kind of compound Chinese herb formula for alleviating laying hen and the negative effect of broiler chicken heat stress one by one in a large amount of clinical tests
And its application.Pharmacological action of the present invention:Understand that laying hen and broiler chicken heat stress clinically belong to according to the dialectical theoretical principle of Chinese veterinarian
Hold heat wetness type humidifier fever under the arm, be wet tired spleen, the hot result for disturbing god.Wrinkled giant hyssop and mulberry leaf are monarchs drug in a prescription in inventive formulation, there is aromatization
Wet, relieving pain by regulating middle-JIAO, inducing diaphoresis is evil, is that the negative effect of the heat stress of full relief chicken plays a crucial role except effect of humidity hysteresis;Raw stone
Cream, sweet wormwood, eupatorium, elscholtiza, the bighead atractylodes rhizome are ministerial drug, reinforcing monarch drug in a prescription appetizing of being amusing, the heat-clearing of Eradicates heat, effect of dispelling dampness and promoting diuresis, jointly
Monarch drug in a prescription is assisted to complete to drive the effect that heat is antipyretic, rouses oneself taste, declare hair body healthy tendency.
Compared with prior art, advantage of the invention is that:
1st, the compound Chinese herb of anti-chicken high temperature heat stress provided by the present invention, can effectively alleviate current laying hen and broiler chicken life
The negative effect that heat stress syndrome group is brought in production, is a kind of safe, new, efficiently anti-chicken heat shock Chinese medicine preparation production
Product;
2nd, the compound Chinese herb of anti-chicken high temperature heat stress provided by the present invention, is made up of, no spy natural traditional Chinese medicine completely
Different processing procedure, process is extremely simple, is ecosystem, all-natural product, is production safety, ecology, the high-quality chicken of green
Egg and chicken lay the foundation;
3rd, the compound Chinese herb of anti-chicken high temperature heat stress provided by the present invention, consumption is shown after applying in production
The characteristics of small, instant effect, effect stability, be a kind of preferable Chinese herbal medicine formula product.
Embodiment
In order that those skilled in the art more fully understand and implement the present invention, with reference to specific embodiment furtherly
The bright present invention.But herein below should not be understood to that claims of the present invention is claimed the limit of scope in any degree
System.
In example 1 below, 2,3,4, Chinese medicine gypsum place of production Hubei used, wrinkled giant hyssop place of production Guangdong, sweet wormwood, eupatorium,
Mulberry leaf, the bighead atractylodes rhizome, the place of production of elscholtiza are Anhui.The water content of each raw materials of traditional Chinese medicinal materials is less than 12%, and impurity content is less than
0.5%.
A kind of compound Chinese herb formula of anti-chicken high temperature heat stress, by the traditional Chinese medicinal material raw materials system of following weight percent content
Into:Mulberry leaf, 20%;Wrinkled giant hyssop, 29%;Gypsum, 10%;Sweet wormwood, 10%;Eupatorium, 15%;The bighead atractylodes rhizome, 8%;Elscholtiza, 8%.
Above-mentioned each Chinese medicine is distinguished into size-reduced machine to crush, is mixed by the ratio of the required after crossing 80 mesh sieves, is sealed in sealing
It is standby in the good polybag of property.
Embodiment 2
A kind of compound Chinese herb formula of anti-chicken high temperature heat stress, by the traditional Chinese medicinal material raw materials system of following weight percent content
Into:Mulberry leaf, 20%;Wrinkled giant hyssop, 35%;Gypsum, 10%;Sweet wormwood, 10%;Eupatorium, 15%;The bighead atractylodes rhizome, 5%;Elscholtiza, 5%.
Above-mentioned each Chinese medicine is distinguished into size-reduced machine to crush, is mixed by the ratio of the required after crossing 80 mesh sieves, is sealed in sealing
It is standby in the good polybag of property.
Embodiment 3
A kind of compound Chinese herb formula of anti-chicken high temperature heat stress, by the traditional Chinese medicinal material raw materials system of following weight percent content
Into:Mulberry leaf, 18%;Wrinkled giant hyssop, 30%;Gypsum, 10%;Sweet wormwood, 10%;Eupatorium, 12%;The bighead atractylodes rhizome, 10%;Elscholtiza, 10%.
Above-mentioned each Chinese medicine is distinguished into size-reduced machine to crush, is mixed by the ratio of the required after crossing 80 mesh sieves, is sealed in sealing
It is standby in the good polybag of property.
Embodiment 4
A kind of compound Chinese herb formula of anti-chicken high temperature heat stress, by the traditional Chinese medicinal material raw materials system of following weight percent content
Into:Mulberry leaf, 15%;Wrinkled giant hyssop, 25%;Gypsum, 10%;Sweet wormwood, 10%;Eupatorium, 10%;The bighead atractylodes rhizome, 15%;Elscholtiza, 15%.
Above-mentioned each Chinese medicine is distinguished into size-reduced machine to crush, is mixed by the ratio of the required after crossing 80 mesh sieves, is sealed in sealing
It is standby in the good polybag of property.
In order to determine optimal drug proportioning combination, the present invention has carried out clinical effect trial, has carried out checking explanation:
Experiment 1
The basic condition of experiment:
Test period is 22 days to 2014 July in 2014 of on August 22, and place is that Wuhan City Xinzhou District Wang Ji fowl industry is public
Department, temperature on average was 33 DEG C at that time.From 150 ages in days from native miscellaneous laying hen 16000 is cultivated, wherein test chicken 8000 and because having
4 kinds of pharmaceutical formulations and be divided into 4 groups, per each 2000 of group, compare chicken 8000, raise in same hen house, freely lead to
Wind, staged cage is raised, free water, artificial feeding feed, and day feeds 2 times, and feeding is eaten with feed in crib every time is totally
Degree, has residue then to be cleaned and be included in the feed not fed.It is fed with expecting to be responsible for by special messenger daily, and performed in the same day feeding
Expect consumption record.
Observation of curative effect:
Medicine admixes Direct-fed in feed, and dosage accounts for the 1% of complete diet pellet quality.Increased after dispensing with the feed intake of chicken group
Plus amplitude, dead mortality fall, laying rate increase rate, broken rate of eggshell fall be judgment basis, rear root
The calculating of efficiency index is carried out according to the weight of indices in production, formula is as follows:Increased amplitude × the 60%+ of feed intake is dead
Mortality fall × 15%+ laying rate increase rate × 15%+ broken rate of eggshell fall × 10%=effects are died to refer to
Number.
Each group therapeutic effect is shown in Table 1:
Table 1
The efficiency index of herbal mixture prepared by four embodiments of the present invention is maximum with the value of embodiment 1, with other each groups
Difference it is extremely notable, while its feed intake increasing degree is more than more than 10%, anti-heat stress of layer effect is obvious, should with clinic
With value, it is defined as optimum proportioning combination.
In order to further verify present invention combination clinical therapeutic efficacy, verification experimental verification is further carried out
Experiment 2
The basic condition of experiment:
Test period is 22 days to 2014 July in 2014 of on August 22, and place is that Wuhan City Xinzhou District Li Ji fowl industry is public
Department, temperature on average was 33 DEG C at that time.From 380 age in days Roman egghen 20000, wherein test chicken 10000 and because there is 4 kinds of medicines
Composition formula and be divided into 4 groups, per each 2500 of group, compare chicken 10000, raise in two adjacent hen houses, freely lead to
Wind, staged cage is raised, free water, artificial feeding feed, and day feeds 2 times, and feeding is eaten with feed in crib every time is totally
Degree, has residue then to be cleaned and be included in the feed not fed.It is fed with expecting to be responsible for by special messenger daily, and performed in the same day feeding
Expect consumption record.
Observation of curative effect:
Medicine admixes Direct-fed in feed, and dosage accounts for the 1% of complete diet pellet quality.Increased after dispensing with the feed intake of chicken group
Plus amplitude, dead mortality fall, laying rate increase rate, broken rate of eggshell fall be judgment basis, rear root
The calculating of efficiency index is carried out according to the weight of indices in production, formula is as follows:Increased amplitude × the 60%+ of feed intake is dead
Mortality fall × 15%+ laying rate increase rate × 15%+ broken rate of eggshell fall × 10%=effects are died to refer to
Number.
Each group therapeutic effect is shown in Table 2:
Table 2
The efficiency index of herbal mixture prepared by four embodiments of the present invention is maximum with the value of embodiment 1, with other each groups
Difference it is extremely notable, while its feed intake increasing degree is more than more than 10%, anti-heat stress of layer effect is obvious, should with clinic
With value, it is defined as optimum proportioning combination.
Experiment 3
In order to verify using effect of the present invention to broiler chicken, following verification experimental verification is made
The basic condition of experiment:
Test period is 24 days to 2014 July in 2014 of on August 15, and place is Wuhan City Jiangxia District Qin Ye companies,
Temperature on average was 33 DEG C at that time.From the miscellaneous broiler 900 of 19 ages in days soil, wherein test chicken 800 and because there is 4 kinds of medicines to match somebody with somebody
Just it is divided into 4 groups, per each 200 of group, compares chicken 100, raise in same hen house and separated with glue mesh sheet, freely
Ventilation, free water, free choice feeding.Be fed with expecting to be responsible for by special messenger daily, and performed in the same day food consumption recording.
Observation of curative effect:
Medicine admixes Direct-fed in feed, and dosage is carried out by the 1% of complete diet pellet quality.With the feeding of chicken group after dispensing
Increased amplitude, the weightening increasing degree of chicken, the dead mortality fall of chicken are measured for judgment basis, after according to indices
Weight in production carries out the calculating of efficiency index, and formula is as follows:The weightening increase of the increased amplitude of feed intake × 40%+ chickens
Amplitude × 40%+ chicken deaths eliminate reduction amplitude × 20%=efficiency indexs.
Each group therapeutic effect is shown in Table 3:
Table 3
Herbal mixture prepared by four embodiments of the present invention has preferable effect, but efficiency index in the use of broiler chicken
Maximum with the value of embodiment 1, the difference with other each groups is extremely notable, while its feed intake increasing degree is close to 10%, anti-broiler chicken
Heat stress effect is obvious, and the application value to broiler production is big.Therefore determine that the formula of embodiment 1 combines for optimum proportioning.
In summary the result of 4 embodiments is understood, the application of the formulas of 4 embodiments in broiler chicken and laying hen anti-heat stress
Aspect has preferable effect, possesses corresponding practical value.Working condition changes greatly in practice, therefore can be according to reality
Situation selection application.