CN106072218A - A kind of selenium-rich GUILING GAO and preparation method thereof - Google Patents

A kind of selenium-rich GUILING GAO and preparation method thereof Download PDF

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Publication number
CN106072218A
CN106072218A CN201610444052.7A CN201610444052A CN106072218A CN 106072218 A CN106072218 A CN 106072218A CN 201610444052 A CN201610444052 A CN 201610444052A CN 106072218 A CN106072218 A CN 106072218A
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China
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selenium
rich
semen
parts
guiling gao
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Inventor
江凌
吴健华
邱越
张燕金
符彩莉
潘志诚
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GUANGXI WUZHOU GANGSHENGTANG HEALTH-CARE FOOD Co Ltd
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GUANGXI WUZHOU GANGSHENGTANG HEALTH-CARE FOOD Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/58Reptiles
    • A61K35/586Turtles; Tortoises, e.g. terrapins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/68Plantaginaceae (Plantain Family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/884Alismataceae (Water-plantain family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9064Amomum, e.g. round cardamom
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The present invention relates to a kind of selenium-rich GUILING GAO and preparation method thereof, this selenium-rich GUILING GAO is to have reversed the concept of traditional GUILING GAO heat-clearing and toxic substances removing in GUILING GAO, in addition to incorporating selenium-rich Fructus Colocasiae Esculentae, also by adjusting the Chinese prescription coordinating GUILING GAO, changes the property of medicine that original product is cold and cool.In GUILING GAO finished product of the present invention, Se content is not less than 0.005mg/kg, in addition to keeping the original mouthfeel of GUILING GAO with local flavor, also has notable dispelling cold and dampness detoxicating functions.

Description

A kind of selenium-rich GUILING GAO and preparation method thereof
Technical field
The invention belongs to food research field, be specifically related to a kind of selenium-rich GUILING GAO and preparation method thereof.
Background technology
Selenium is the trace element of needed by human.Selenium participates in multiple selenoenzyme and Selenonic protein in synthesized human.Selenium can improve Human immunity, the propagation of promotion lymphocyte and antibody and the synthesis of immunoglobulin.Selenium is to colon cancer, skin carcinoma, hepatocarcinoma, breast The kinds cancers such as adenocarcinoma have significantly suppression and the effect of protection, and its mesostate methyl enol in body has Stronger active anticancer.The nutrients such as selenium and vitamin E, garlicin, linoleic acid, germanium, zinc have collaborative antioxidative effect, energy Enough protect cell membrane, prevent the oxidation of unsaturated fatty acid, increase antioxidant activity, there is protective effect on cancer risk and liver-protective work With.Meanwhile, selenium has the effect alleviating and alleviating heavy metal toxicity.
Selenium-enriched food is just enriched in the food of trace element-selenium, such as southern black Semen Sesami, Semen sojae atricolor, blackcurrant pigment, fructus zizaniae caduciflorae, Bulbus Allii Selenium element is all contained Deng black food and the rice of district rich in selenium production, Rhizomadioscoreae, Semen arachidis hypogaeae, Semen Phaseoli, Semen Glycines etc..Worked out in 2000 The recommended intake of " DRIs " more than 18 years old person be 50 μ g/d, suitable intake is 50-250 μ g/d, can tolerate the highest intake is 400 μ g/d.An application form was made by Chinese Soclety of Nutrition in 13 provinces and cities of China Bright, Coming-of-Age Day average selenium intake is 26-32 microgram, and bottom line 50 microgram recommended from Chinese Soclety of Nutrition is far apart. Therefore, exploiting economy, convenience, the selenium-enriched food being suitable for being eaten for a long time is the most imperative.
After modern eats various cold and cool gourd, fruit and vegetable regardless of season the most by mistake, after people are at summer life-time service air-conditioning, After ladies are in order to show that stature is worn the clothes less as far as possible, a large amount of cold-damp the most quietly enter internal, and natural kidney fire is the most not Foot, asthenic fire is the most increasing.And generally all use pathogenic fire purging, relieve inflammation or internal heat, the cold and cool medicine of pathogenic fire reducing is treated, this allows for adding on cold Add void in cold, void, more control fire the biggest.The cold direct result remake in health is impairment of the kidney exactly, causes insufficiency of kidney-YANG, kidney qi Void, causes each organ function to decline, blood virtual loss.Human body once hydropenia, liver is dry, liver-fire clearly.First head goes out simultaneously Existing ischemia, that is " hydropenia ", as cadre's symptom all occur in eye ear mouth and nose, easily infected by antibacterial, and immunologic function just declines, and can go out Existing various discomforts.Thousand cold easily go, and a wet difficulty is removed, no matter diseases caused by exogenous pathogenic factor cold-damp or interior raw cold-damp, the most deeply stay in human body, it is difficult to dial and remove.
Tradition GUILING GAO produces and forms with Raw material processings such as water, bean jelly, Poria, Testudinis, adjuvants at present, has nutrition and heat clearing away Detoxication health care effect.But owing to the primary efficacy of tradition GUILING GAO is heat-clearing and toxic substances removing, it is primarily adapted for use in damp-heat area, south, Its for edible crowd and edible territorial scope the narrowest, do not have the product for cold-damp at present, improve human immunity merit Efficacious prescriptions face remains in disappearance.Nutrition and effect of promoting GUILING GAO are worth the optimization and upgrading that can advance this product, are up to push away Wide GUILING GAO product and the breach by dietetic therapy solution Modern human populations widespread need.
Summary of the invention
It is an object of the invention to provide a kind of selenium-rich GUILING GAO, add selenium-enriched crop products to Testudinis as primary raw material In Siberian cocklebur paste formulation, develop selenium-rich GUILING GAO series of products.
In selenium-rich GUILING GAO of the present invention, Se content is not less than 0.005mg/kg.
Preferably, GUILING GAO of the present invention includes the raw material of following weight portion: Testudinis 5~50 parts, bean jelly 600~1000 Part, Poria 10~50 parts, selenium-rich finished product of grain 1000~3000 parts.
Preferably, described selenium-rich finished product of grain includes: in water fruits and vegetables, beans, miscellaneous grain crops any one or more.
Preferably, described selenium-rich finished product of grain include following one or more: Rhizoma Solani tuber osi, Radix Dauci Sativae, Rhizoma Dioscoreae, Fructus Colocasiae Esculentae, sweet Potato, Radix Puerariae, Rhizoma Nelumbinis, Bulbus Lilii, Corm Eleocharitis, white turnip, taro, mushroom taro, Jerusalem artichoke, Rhizoma sagittariae sagittifoliae, Bulbus Allii Macrostemonis, root-mustard, Folium Braseniae Schreberi, Caulis et Folium Lactucae sativae, Caulis Zizaniae caduciflorae, stone Diao Bai, bamboo sprout, kohlrabi, Radix Ginseng, Semen Phaseoli, Semen Glycines, Semen sojae atricolor, Semen phaseoli radiati, Semen Viciae fabae, Semen Pisi sativi, Kidney bean, Semen Canavaliae, Seem Lablab Album, Semen sojae atricolor, dish Bean, Semen Cajani, Semen Psophocarpi tetragonolobi, chickpea, Lens culinaris Medic., white jade bean, Semen vignae sinensis, Semen Phaseoli Vulgaris, Oryza glutinosa, Semen Tritici aestivi, Semen Fagopyri Esculenti, Radix Et Rhizoma Fagopyri Tatarici, Herba bromi japonici, broom corn millet, broomcorn millet Son, Semen Maydis, Rhizoma Dioscoreae esculentae, Rhizoma Steudnerae Henryanae, Sorghum vulgare Pers., Semen Coicis, grain Herba Amaranthi tricoloris, Semen setariae, brown rice, southern black Semen Sesami, blackcurrant pigment, fructus zizaniae caduciflorae, Fructus Mangifera Indicae, Fructus Ananadis comosi, Garcinia mangostana, Durio Zibethinus murr, Fructus Mali pumilae, Fructus Persicae, Fructus Musae, Citrus, Fructus Vitis viniferae.
Preferably, in described selenium-rich finished product of grain, Se content is not less than 0.06mg/kg.
Preferably, described raw material also includes the Chinese crude drug that following weight portion forms:
Semen Plantaginis 20~70 parts, Poria 20~70 parts, Rhizoma Alismatis 15~40 parts, the Rhizoma Atractylodis Macrocephalae 15~40 parts, Radix Achyranthis Bidentatae 15~40 parts, Ramulus Cinnamomi 10 ~45 parts, Fructus Amomi 8~30 parts.
Preferably, described raw material also includes the Chinese crude drug that following weight portion forms:
Semen Plantaginis 30 parts, 30 parts of Poria, Rhizoma Alismatis 20 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, Radix Achyranthis Bidentatae 20 parts, Ramulus Cinnamomi 15 parts, Fructus Amomi 10 parts.
The present invention also provides for the preparation method of a kind of selenium-rich GUILING GAO, and step includes:
(1) weigh selenium-rich finished product of grain by formula ratio and pass through flushing, peeling, ripening, defibrination, standby;
(2) the whole raw materials weighed in addition to selenium-rich finished product of grain, bean jelly by formula ratio, clean, and add water soaking, extract, and filter, filter Liquid is standby;
(3) weigh bean jelly by formula ratio, stir with 5~20 times of water, standby;
(4) above step (1)~the standby material of (3) gained are pumped into mixing in digester, heats while stirring, high pressure homogenize, Filter, subpackage, high temperature sterilization, to obtain final product.
Preferably, in step (2), raw material cleans and uses circulating water to clean 1-4 time, and filter is duplex strainer, fire-bar Part is that temperature controls to keep 0.5~2 hour at 90~110 DEG C.
Preferably, step (4) gained spares mixes, and heats while stirring, and described heating-up temperature is 60~80 DEG C, the time 20~60 minutes;Sieves mesh number is 100~200 mesh.
The present invention also provides for the preparation method of a kind of selenium-rich GUILING GAO, and step includes:
(1) weighing selenium-rich finished product of grain by formula ratio, rinse well, after conventional treatment, make the particulate of 0.2~1.0cm, blanching is standby With;
(2) medicinal material extract: the whole raw materials weighed in addition to selenium-rich finished product of grain, bean jelly by formula ratio, after adding 2-10 times of water soaking, Heating extraction 1-3 hour, filters, and concentrates, standby;
(3) weigh bean jelly by formula ratio, stir with 0.5-2 times of water, standby;
(4) the standby material mixing after step (2), (3) preparation, sugaring, Mel, it is heated to 60-80 DEG C, uniform stirring 0.5-1 hour, through high pressure homogenize, filter, subpackage;
(5) step (1) gained standby selenium-rich finished product of grain particulate it is eventually adding;Sealing, sterilization, to obtain final product.
The following is the raw material sources of the present invention:
Testudinis: for Chelonia animal Testudinis.
Poria: for the dry sclerotia of On Polyporaceae Poria Poria cocos (Schw.) Wolf.[nature and flavor with return Warp] sweet, light, flat.GUIXIN, lung, spleen, kidney channel.[function with cure mainly] promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming.For edema oliguria, phlegm retention Vertigo and palpitation, insufficiency of the spleen lack of appetite, loose stool has loose bowels, irritability, palpitation with fear insomnia.
Bean jelly: by lip plant bean jelly platymiscium Mesona Chinensis Benth herb extract, be dried be prepared from.
Semen Plantaginis: for Plantaginaceae plant Herba Plantaginis Plantago asiatica L. or Plantago depressa Willd Plantago depressa Willd. dry mature seed.[nature and flavor with return through] are sweet, cold.Return liver, kidney, lung, small intestine meridian.[function with cure mainly] clearing away heat and promoting diuresis Treating stranguria, eliminating dampness by diuresis antidiarrheal, improving eyesight, eliminate the phlegm.For the puckery pain of pyretic stranguria, edema distension, diarrhea due to summer heat and dampness, conjunctival congestion and swelling pain, phlegm-heat cough.
Rhizoma Alismatis: for the dry tuber of Notes On Alism At Aceae Rhizoma Alismatis Alisma orientalis (Sam.) Juzep..[nature and flavor With return through] sweet, light, cold.Return kidney, bladder warp.[function with cure mainly] promoting diuresis to eliminate damp pathogen, expels the heat-evil, changes turbid blood fat reducing.For dysuria, Edema distension, oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria, hyperlipemia.
The Rhizoma Atractylodis Macrocephalae: for the dry rhizome of feverfew Rhizoma Atractylodis Macrocephalae Atract μ lodes macrocephala Koidz..[nature and flavor With return through] bitter, sweet, temperature.Return spleen, stomach warp.[function with cure mainly] invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen food Few, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Radix Achyranthis Bidentatae: for the dry root of amaranthaceous plant Radix Achyranthis Bidentatae Achyranthes bidentata Bl..[nature and flavor with return through] bitter, Sweet, sour, flat.Return liver, kidney channel.[function with cure mainly] eliminating blood stasis and inducing menstruation, invigorating the liver and kidney, bone and muscle strengthening, inducing diuresis for treating stranguria syndrome, conducting blood to flow downwards.For Amenorrhea, dysmenorrhea, soreness of waist and knee joint, muscles and bones is unable, stranguria, edema, headache, dizziness, toothache, day skin ulcer, spit blood, epistaxis.
Ramulus Cinnamomi: for the dry twig of canella Cortex Cinnamomi Cinnamomum cassia Presl.[nature and flavor with return through] pungent, Sweet, temperature.GUIXIN, lung, bladder warp.[function with cure mainly] diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.For wind and cold Flu, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Fructus Amomi: for zingiberaceous plant Fructus Amomi Amomum villosum Lour., green shell sand Amomum villosum Lour. var. xanthioides T. L. Wu et Senjen or SEMEN AMOMI LONGILIGULA Amomum longiligulare T. L. The dry mature fruit of Wu.[nature and flavor with return through] are pungent, temperature.Return spleen, stomach, kidney channel.[function with cure mainly] removing dampness appetizing, warming the spleen is only Rush down, regulate the flow of vital energy antiabortive.For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is the most hungry, Deficiency and coldness of spleen and stomach, and vomiting is had loose bowels, pregnancy reactions, frequent fetal movement.
Semen Phaseoli: i.e. Semen adenantherae pavoninae (formal name used at school: Adenanthera pavonina Linn. var. microsperma) Herba Mimosae Pudicae Section's beadtree, calls Semen Phaseoli, red rice bean, rice Semen Phaseoli, barbadoes pride, yearning between lovers lattice.[nature and flavor with return through] are sweet, sour, flat.GUIXIN, little Intestinal warp.[function with cure mainly] inducing diuresis to remove edema, removing toxic substances and promoting pus discharge.For edema distension, beriberi edema, jaundice dark coloured urine, beriberoid pyretic arthralgia, carbuncle Swollen sore, abdominalgia with intestinal abscess.
Selenium-rich finished product of grain: Se content index during Se content meets " China's selenium-enriched food mark " trade management specification in selenium-rich raw material Regulation, or meet Guangxi Local standard " Se-rich farm products Se content classificating requirement ".Preferably, the selenium in selenium-rich finished product of grain For endogenous selenium, come from soil itself rather than spill spray absorption by outside.
Modern society increasingly payes attention to health preserving, and modern society most people, due to a variety of causes, exist under immunity in various degree Dropping, cancer incidence is constantly climbed to a higher point, and body degree of oxidation accelerates;And owing to diseases caused by exogenous pathogenic factor cold-damp and Nei Sheng cold-damp cause internal savings big The dampness of amount.In cold-damp tired and damage spleen sun, or deficiency of spleen-YANG and kidneyYANG and stop in cold-damp, with aversion to cold and cold limbs, stomachache is had loose bowels, or edema is The syndrome of common disease.Applicant has developed a selenium-rich GUILING GAO for this phenomenon, with dietetic therapy preventive treatment of disease, strengthen health element Matter, effectively reaches to improve body immunity, anti-cancer and antioxidation.New effect GUILING GAO of the application also solves tradition Testudinis Siberian cocklebur cream only has heat-clearing toxin-expelling functions, the problem being only applicable to damp and hot area crowd, makes more area and people's group energy enjoy GUILING GAO this make us the oiliness traditional product of food.
Cold-damp syndrome, by deficiency of spleen-YANG and kidneyYANG, stops in aqueous vapor and causes.Water made at spleen, is led at kidney.Kidney person, the pass of stomach also, modern kidney yang Void, Guan Shui is unfavorable, therefore polywater and from its class also.Upper underflow is in skin, therefore is edema, edema person, polywater and sick also.Spleen positive group In kidney yang, existing kidney yang deficiency, then spleen sun is the most not enough.The wet transporting of the main water of spleen, deficiency of spleen-YANG can not transporting, then water liquid stops poly-and is all Suffer from.Method for the treatment of should be with warming and recuperating the kidney-YANG and promoting diuresis to eliminate damp pathogen R. concomitans.
The hot pure sun of Ramulus Cinnamomi in side of the present invention, the kidney warming is mended fire, the void of energy kidney-replenishing, is helped answering of gasification;Ramulus Cinnamomi also can open the natural fibre line of meat Diaphoresis, makes the water at table, lets out from skin.Carapax Et Plastrum Testudinis energy nourishing YIN for benefiting the kidney, therefore treating YANG within YIN, make sun medicine Ramulus Cinnamomi can obtain cloudy medicine Carapax Et Plastrum Testudinis it Help and augment the power of sun.Both share, and sun medicine obtains the soft and moist then temperature of cloudy medicine and the driest, cloudy medicine obtain positive medicine the taste of temperature general rule and not Greasy, bring out the best in each other, be monarch drug altogether.Rhizoma Alismatis, Semen Plantaginis merit arrogate to oneself promoting diuresis to eliminate damp pathogen, for swollen, the good medicine of dysuria of harnessing the river.Poria, white Art replenishing QI to invigorate the spleen, Semen Phaseoli is drying damp and strengthening spleen, is the method for high soil controlling the water circulation.Radix Achyranthis Bidentatae liver and kidney tonifying and sliding profit is descending, coordinate pool, car, Fu, Bai Ze The benefit of inducing diuresis to remove edema.Above six close Ramulus Cinnamomi can warming YANG to promote diuresis, treating both the principal and secondary aspects of a disease, be all ministerial drug.Herba mesonae chinensis has heat-clearing and toxic substances removing Merit, assistant with top, then double can control the disease of pyretic stranguria, be for adjuvant drug.Damp being a kind of YIN pathogen, easy air resister, Fructus Amomi is longer than promoting the circulation of QI to induce diuresis, makes Gasify and the wettest also change, be equipped with top, then the merit of damp eliminating is notable, is for making medicine.All medicines share, and supporing yang is weak to change water, YIN nourishing it Void, with anger, makes kidney yang rouse oneself, and gasification is multiple often.Gas transports then water humidifying again, and swelling disappears and all diseases are poor.
The invention have the advantages that
1, in selenium-rich Fructus Colocasiae Esculentae GUILING GAO, Se content is not less than 0.005mg/kg, by daily dietetic therapy, can reach to improve human body and exempt from Epidemic disease, anti-cancer, antioxidative effect.
2, after the Chinese prescription of the present invention and three taste basic materials of tradition GUILING GAO combine, former GUILING GAO is not only kept Local flavor, and there is human immunity, anti-cancer, antioxidation, the dispelling cold and dampness effect of significantly improving, according to clinical verification, it improves human body and exempts from Epidemic disease power effective percentage reaches 90%, and dispelling cold and dampness effective percentage reaches 92%.
Detailed description of the invention
Following example are used for illustrating the present invention, but are not limited to the scope of the present invention.
Embodiment 1: selenium-rich Semen Tritici aestivi GUILING GAO
Weigh the raw material of following weight: Testudinis 5kg, bean jelly 600 kg, Poria 10 kg, selenium-rich Semen Tritici aestivi 1000 kg, Semen Plantaginis 20kg, Poria 20kg, Rhizoma Alismatis 15kg, Rhizoma Atractylodis Macrocephalae 15kg, Radix Achyranthis Bidentatae 150kg, Ramulus Cinnamomi 10kg, Fructus Amomi 8kg.
(1) selenium-rich Semen Tritici aestivi is taken, through flushing, peeling, ripening, defibrination, standby;
(2) remove the whole raw materials outside selenium-rich Semen Tritici aestivi, bean jelly, after being placed in clear water washing 1 time, put into extraction pot, add pure Water soaking, heating extraction, temperature controls to keep 0.5 hour at 90 DEG C, and after using duplex strainer to filter, filtrate is standby;
(3) take bean jelly, stir with 5 times of pure water, standby;
(4) will mix in above step (1)~the standby material of (3) gained pump into digester, be heated to 60 DEG C, the most uniformly Stirring 20 minutes, high pressure homogenize, filter with 100 mesh filter screens, subpackage, high temperature sterilization, temperature controls at 110 DEG C, 30 minutes time, Get product.
Testing result: selenium-rich Semen Tritici aestivi raw material Se content is 0.06mg/kg, in gained selenium-rich Semen Tritici aestivi GUILING GAO, Se content is 0.005mg/kg。
Embodiment 2: selenium enriched black peanut GUILING GAO
Weigh the raw material of following weight: Testudinis 10kg, bean jelly 800 kg, Poria 20 kg, selenium enriched black peanut 2500 kg, Semen Plantaginis 30kg, Poria 30kg, Rhizoma Alismatis 20kg, Rhizoma Atractylodis Macrocephalae 20kg, Radix Achyranthis Bidentatae 20kg, Ramulus Cinnamomi 15kg, Fructus Amomi 10kg.
(1) selenium enriched black peanut is taken, through flushing, peeling, ripening, defibrination, standby;
(2) remove the whole raw materials outside selenium enriched black peanut, bean jelly, after being placed in clear water washing 1 time, put into extraction pot, add pure Water purification soaks, heating extraction, and temperature controls to keep 1 hour at 100 DEG C, and after using duplex strainer to filter, filtrate is standby;
(3) take bean jelly, stir with 10 times of pure water, standby;
(4) will mix in above step (1)~the standby material of (3) gained pump into digester, be heated to 70 DEG C, the most uniformly Stirring 40 minutes, high pressure homogenize, filter with 150 mesh filter screens, subpackage, high temperature sterilization, temperature controls at 110 DEG C, 30 minutes time, Get product.
Testing result: selenium enriched black peanut raw material Se content is 0.25mg/kg, Se content in gained selenium enriched black peanut GUILING GAO For 0.02mg/kg.
Embodiment 3: selenium-rich Semen Coicis GUILING GAO
Weigh the raw material of following weight: Testudinis 50kg, bean jelly 1000 kg, Poria 50 kg, selenium-rich Semen Coicis 2000 kg, Semen Plantaginis 70kg, Poria 70kg, Rhizoma Alismatis 40kg, Rhizoma Atractylodis Macrocephalae 40kg, Radix Achyranthis Bidentatae 40kg, Ramulus Cinnamomi 45kg, Fructus Amomi 30kg.
(1) selenium-rich Semen Coicis is taken, through flushing, peeling, ripening, defibrination, standby;
(2) remove the whole raw materials outside selenium-rich Semen Coicis, bean jelly, after being placed in clear water washing 1 time, put into extraction pot, add pure Water soaking, heating extraction, temperature controls to keep 2 hours at 110 DEG C, and after using duplex strainer to filter, filtrate is standby;
(3) take bean jelly, stir with 20 times of pure water, standby;
(4) will mix in above step (1)~the standby material of (3) gained pump into digester, be heated to 80 DEG C, the most uniformly Stirring 60 minutes, high pressure homogenize, filter with 200 mesh filter screens, subpackage, high temperature sterilization, temperature controls at 110 DEG C, 30 minutes time, Get product.
Testing result: selenium-rich Semen Coicis raw material Se content is 0.2mg/kg, gained selenium-rich Semen Coicis GUILING GAO Se content is 0.02mg/kg。
Embodiment 4: maize rich in selenium GUILING GAO
Weigh the raw material of following weight: Testudinis 5kg, bean jelly 600 kg, Poria 10 kg, maize rich in selenium 3000 kg, Semen Plantaginis 20kg, Poria 20kg, Rhizoma Alismatis 15kg, Rhizoma Atractylodis Macrocephalae 15kg, Radix Achyranthis Bidentatae 150kg, Ramulus Cinnamomi 10kg, Fructus Amomi 8kg.
(1) weighing maize rich in selenium by formula ratio, rinse well, make the particulate of 0.2~1.0cm, blanching is standby;
(2) medicinal material extract: the whole raw materials weighed in addition to maize rich in selenium, bean jelly by formula ratio, after adding 2 times of water soakings, heating Extract 1 hour, filter, concentrate, standby;
(3) weigh bean jelly by formula ratio, stir with 0.5 times of water, standby;
(4) mixing of gained standby material, sugaring, Mel being prepared in step (2), (3), be heated to 60 DEG C, uniform stirring 0.5 is little Time, through high pressure homogenize, filter, subpackage;
(5) step (1) gained standby maize rich in selenium particulate it is eventually adding;Sealing, sterilization, to obtain final product.
Testing result: maize rich in selenium raw material Se content is 0.34mg/kg, gained maize rich in selenium GUILING GAO Se content is 0.03mg/kg。
Embodiment 5: selenium-rich Semen Phaseoli GUILING GAO
Weigh the raw material of following weight: Testudinis 10kg, bean jelly 800 kg, Poria 20 kg, selenium-rich Semen Phaseoli 2500 kg, Semen Plantaginis 70kg, Poria 70kg, Rhizoma Alismatis 40kg, Rhizoma Atractylodis Macrocephalae 40kg, Radix Achyranthis Bidentatae 40kg, Ramulus Cinnamomi 45kg, Fructus Amomi 30kg.
(1) weighing selenium-rich Semen Phaseoli by formula ratio, rinse well, blanching is standby;
(2) medicinal material extract: the whole raw materials weighed in addition to selenium-rich Semen Phaseoli, bean jelly by formula ratio, after adding 2-10 times of water soaking, adds Heat is extracted 1-3 hour, filters, and concentrates, standby;
(3) weigh bean jelly by formula ratio, stir with 0.5-2 times of water, standby;
(4) the standby material mixing after step (2), (3) preparation, sugaring, Mel, being heated to 60-80 DEG C, uniform stirring 1 is little Time, through high pressure homogenize, filter, subpackage;
(5) step (1) gained standby selenium-rich Semen Phaseoli it is eventually adding;Sealing, sterilization, to obtain final product.
Testing result: selenium-rich Semen Phaseoli raw material Se content is 0.15mg/kg, in gained selenium-rich Semen Phaseoli GUILING GAO, Se content is 0.01mg/kg。
Test effect:
One, enhancing immunity test
The enhancing immunity effect of GUILING GAO of the present invention is carried out analysis of experiments.
1, subjects: exclusion standard: took the medicine relevant with tested function or health product person in the nearlyest month;② Be addicted to drink, junkie;3. there are health product allergies and other severe allergies history person.
2, case selection: 60 volunteers (female 32 people, male 28 people), age 30-55 year.
Cardinal symptom: have a delicate constitution, malnutrition, lethargy, fatigue and weak, appetite reduce, sleep disorder, often give birth to Disease, recovers slowly.It is judged to hypoimmunity disease through the traditional Chinese medical science.
3, test packet: the volunteer of 30 above-mentioned symptoms is set as, and experimental group, another 30 volunteers are set as comparison Group.
4, test method: experimental group is administered orally the present embodiment 5 GUILING GAO product, every day 250g, totally 60 days;Matched group is tested Period does not take any Related product or medicine.All volunteers normal diet during testing, does not change original diet and practises Used.
5, method of testing: the physical condition change of each experimenter before and after observation survey test.
6, curative effect index:
Effective: disease disappears;
Take a turn for the better: remission;
Invalid: disease is not improved.
7, therapeutic outcome: observe the efficacy result of two groups after 60 days, the most as shown in table 1:
Table 1 result of the test
Group Number of cases Total effective rate Effectively Take a turn for the better Invalid
Experimental group 30 90.0% 10 17 3
Matched group 30 23.3% 3 4 23
Note: total effective rate is effectively to represent with improvement sum.
Knowable to table 1 result of the test, illustrate that the present invention can improve body immunity, can prevent and treat by immunity low Under the various diseases that cause.
Two, treatment cold-damp clinical trial
1, subjects: spleen-stomach deficiency-cold gastric abscess is suffered from.
2, case selection: 50 volunteers (female 26 people, male 24 people), age 25-65 year.
Inclusive criteria: all patients meet chronic gastritis under the symptom of traditional Chinese medical science spleen-stomach deficiency-cold gastric abscess and clinical endoscopic Diagnostic criteria: 1. upper abdomen nearly precordial region dull pain, belch, mouth vomiting watery fluid, meet after gentleness is gently rubbed and alleviate, pain adds the most on an empty stomach Weight, the thinnest, white and greasy fur, pulse is heavy thin;This disease recurrent exerbation, particularly tired, after spirit is smooth and dietary habit changes Exacerbation of symptoms.2. under electronic gastroscope, there is change red and white in stomach or duodenum portion mucous membrane surface, or with erosion, mucosa Lower blood vessel sees through or the iconography signs such as ulcer occurs.
Exclusion standard: the serious symptom gastric ulcer 1. caused by chronic gastritis or gastric perforation patient.2. non-with stomach mucosa Typical case's hypertrophy or stomach malignant tumor patient.3. upper abdomen and the other diseases of precordial region dull pain are caused: angina pectoris, chronic pancreas The diseases such as inflammation and myocardial infarction.4. with hypertension, heart disease and hepatic renal dysfunction, drug allergy person.
3, test packet: the volunteer of 25 above-mentioned symptoms is set as, and experimental group, another 25 volunteers are set as comparison Group.
4, test method: experimental group is administered orally the present embodiment 5 selenium-rich Semen Phaseoli GUILING GAO product, every day 250g, totally 60 days;Right Refuse to obey with any Related product or medicine according to during group test.All volunteers normal diet during testing, does not change original Dietary habit.
5, method of testing: the physical condition change of each experimenter before and after observation survey test.
6, curative effect index:
Effective: the transference cures such as patient's poor appetite, belch, abdominal distention, mouth vomiting watery fluid and abdominal pain, through gastroscopy stomach mucosa The inflammation such as surface is red and white, blood vessel sees through performance disappears or substantially changes.
Take a turn for the better: clinical symptom relief or the decreased duration such as patient's belch, poor appetite and stomachache, patient's mouth vomiting watery fluid is sent out Making number of times to reduce, gastroscopy mucosa inflammatory disorders alleviates or is negative performance.
Invalid: after treatment, above-mentioned clinical symptoms and gastroscopy result even increase the weight of without significant change.
7, therapeutic outcome: observe the efficacy result of two groups after 60 days, the most as shown in table 2:
Table 2 result of the test
Group Number of cases Total effective rate Effectively Take a turn for the better Invalid
Experimental group 25 92.0% 9 14 2
Matched group 25 20.0% 1 4 20
Note: total effective rate is effectively to represent with improvement sum.
Table 2 result shows, the present invention can effectively treat the various diseases that cold-damp causes.
Conclusion:
Knowable to Tables 1 and 2 result of the test, the total effective rate of the present invention is significantly larger than matched group, illustrates that the present invention can significantly carry High body immunity, enhancing body function, cold-damp is accumulate for a long time the asthenic cold type gastralgia caused there is significant therapeutic effect.
Although, use general explanation, detailed description of the invention and test, the present invention is described in detail, but On the basis of the present invention, can make some modifications or improvements it, this will be apparent to those skilled in the art.Cause This, these modifications or improvements without departing from theon the basis of the spirit of the present invention, belong to the scope of protection of present invention.

Claims (9)

1. a selenium-rich GUILING GAO, it is characterised in that in described selenium-rich GUILING GAO, Se content is not less than 0.005mg/kg.
Selenium-rich GUILING GAO the most according to claim 1, it is characterised in that include the raw material of following weight portion: Testudinis 5~50 parts, Bean jelly 600~1000 parts, Poria 10~50 parts, selenium-rich finished product of grain 1000~3000 parts.
Selenium-rich GUILING GAO the most according to claim 2, it is characterised in that described selenium-rich finished product of grain includes: water fruits and vegetables, bean In class, miscellaneous grain crops any one or more.
Selenium-rich GUILING GAO the most according to claim 3, it is characterised in that described selenium-rich finished product of grain includes following one or More than Zhong: Rhizoma Solani tuber osi, Radix Dauci Sativae, Rhizoma Dioscoreae, Fructus Colocasiae Esculentae, Rhizoma Dioscoreae esculentae, Radix Puerariae, Rhizoma Nelumbinis, Bulbus Lilii, Corm Eleocharitis, white turnip, taro, mushroom taro, Jerusalem artichoke, kind Aunt, Bulbus Allii Macrostemonis, root-mustard, Folium Braseniae Schreberi, Caulis et Folium Lactucae sativae, Caulis Zizaniae caduciflorae, asparagus, bamboo sprout, kohlrabi, Radix Ginseng, Semen Phaseoli, Semen Glycines, Semen sojae atricolor, Semen phaseoli radiati, Semen Viciae fabae, Semen Pisi sativi, Kidney bean, Semen Canavaliae, Seem Lablab Album, Semen sojae atricolor, Kidney bean, Semen Cajani, Semen Psophocarpi tetragonolobi, chickpea, Lens culinaris Medic., white jade bean, Semen vignae sinensis, Semen Phaseoli Vulgaris, Oryza glutinosa, Semen Tritici aestivi, Semen Fagopyri Esculenti, Radix Et Rhizoma Fagopyri Tatarici, Herba bromi japonici, broom corn millet, broomcorn millet, Semen Maydis, Rhizoma Dioscoreae esculentae, Rhizoma Steudnerae Henryanae, Sorghum vulgare Pers., Semen Coicis, grain Herba Amaranthi tricoloris, Semen setariae, brown rice, south Side Semen Sesami Nigrum, blackcurrant pigment, fructus zizaniae caduciflorae, Fructus Mangifera Indicae, Fructus Ananadis comosi, Garcinia mangostana, Durio Zibethinus murr, Fructus Mali pumilae, Fructus Persicae, Fructus Musae, Citrus, Fructus Vitis viniferae.
Selenium-rich GUILING GAO the most according to claim 2, it is characterised in that in described selenium-rich finished product of grain, Se content is not less than 0.06mg/kg。
Selenium-rich GUILING GAO the most according to claim 2, it is characterised in that described raw material also includes what following weight portion formed Chinese crude drug:
Semen Plantaginis 20~70 parts, Poria 20~70 parts, Rhizoma Alismatis 15~40 parts, the Rhizoma Atractylodis Macrocephalae 15~40 parts, Radix Achyranthis Bidentatae 15~40 parts, Ramulus Cinnamomi 10 ~45 parts, Fructus Amomi 8~30 parts.
Selenium-rich GUILING GAO the most according to claim 6, it is characterised in that described raw material includes the Chinese crude drug of following weight portion:
Semen Plantaginis 30 parts, 30 parts of Poria, Rhizoma Alismatis 20 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, Radix Achyranthis Bidentatae 20 parts, Ramulus Cinnamomi 15 parts, Fructus Amomi 10 parts.
Selenium-rich GUILING GAO the most according to claim 4, it is characterised in that be prepared from by following methods:
(1) weigh selenium-rich finished product of grain by formula ratio and pass through flushing, peeling, ripening, defibrination, standby;
(2) the whole raw materials weighed in addition to selenium-rich finished product of grain, bean jelly by formula ratio, clean, and add water soaking, extract, and filter, filter Liquid is standby;
(3) weigh bean jelly by formula ratio, stir with 5~20 times of water, standby;
(4) above step (1)~the standby material of (3) gained are pumped into mixing in digester, heats while stirring, high pressure homogenize, Filter, subpackage, high temperature sterilization, to obtain final product.
Selenium-rich GUILING GAO the most according to claim 4, it is characterised in that be prepared from by following methods:
(1) weighing selenium-rich finished product of grain by formula ratio, rinse well, after conventional treatment, make the particulate of 0.2~1.0cm, blanching is standby With;
(2) medicinal material extract: the whole raw materials weighed in addition to selenium-rich finished product of grain, bean jelly by formula ratio, after adding 2-10 times of water soaking, Heating extraction 1-3 hour, filters, and concentrates, standby;
(3) weigh bean jelly by formula ratio, stir with 0.5-2 times of water, standby;
(4) the standby material mixing after step (2), (3) preparation, sugaring, Mel, it is heated to 60-80 DEG C, uniform stirring 0.5-1 hour, through high pressure homogenize, filter, subpackage;
(5) step (1) gained standby selenium-rich finished product of grain particulate it is eventually adding;Sealing, sterilization, to obtain final product.
CN201610444052.7A 2016-06-20 2016-06-20 A kind of selenium-rich GUILING GAO and preparation method thereof Pending CN106072218A (en)

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CN109601935A (en) * 2019-01-31 2019-04-12 江苏中农科食品工程有限公司 A kind of production method of selenium-rich dragon fruit jam

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CN107836714A (en) * 2017-11-30 2018-03-27 韦志春 A kind of selenium-rich bean jelly and preparation method thereof
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Application publication date: 20161109