CN103875973A - Feed additive for laying hens at egg producing period and preparation method of feed additive - Google Patents
Feed additive for laying hens at egg producing period and preparation method of feed additive Download PDFInfo
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Abstract
The invention discloses a feed additive for laying hens at an egg producing period and a preparation method of the feed additive. The feed additive comprises traditional Chinese medicine additives, an enzyme composition and vitamin D3, wherein the weight part ratio of the traditional Chinese medicine additives to the enzyme composition to the vitamin D3 is 1 to 1 to (0.01-0.5); the traditional Chinese medicine additives comprise following raw material medicines: seaweeds, rhizoma atractylodis, codonopsis pilosula, pseudostellaria heterophylla, chrysanthemums, symphytum officinale, pollen, salvinia natans, endothelium corneum gigeriae galli, poncirus trifoliata, fructus amomi, Chinese yams, hyacinth beans, jujubes, curculigo orchioides, medlar, walnut kernels, semen cuscutae, glutinous rice root hairs and maidenhairs. The feed additive has the beneficial effects of containing the traditional Chinese medicine additives and having the effects of tonifying spleen, eliminating dampness, tonifying kidney and spleen; compared with those in other raw materials, the content of cholesterol of eggs of the laying hens can be reduced, and the laying rate and the egg weight are increased; the disease resisting capability of the laying hens can also be improved.
Description
Technical field
The present invention relates to contain the animal-breeding feed additive that derives from plant, animal or raw mineral materials, particularly a kind of laying cycle of laying hens feed addictive and preparation method thereof.
Background technology
Egg is chosen as " breakfast of nutrition in the world " by a certain magazine of the U.S..According to this section of magazine, egg not only contains the multiple nutrients material that people know, and it also contains two seed amino acids---and tryptophan and tyrosine, these two kinds of acid can help human body anti-oxidant.
Egg is one of best source of nutrition of the mankind, contains a large amount of vitamin and mineral matter and have the protein of high biological value in egg.For people, protein quality the best of egg, is only second to breast milk.A heat that egg is contained, be equivalent to the heat of half apple or half cup milk, but it also has 8% phosphorus, 4% zinc, 4% iron, 12. 6% protein, 6% vitamin D, 3% vitamin E, 6% vitamin A, 2% Cobastab, 5% vitamin B2,4% pyridoxamine.These nutrition are all that human body is requisite, and they play an important role, as repaired tissue, form the metabolic processes etc. of new tissue, consumed energy and participation complexity.
In egg yolk, contain more cholesterol, every hectogram can be up to 1510 milligrams, and therefore, Bu Shaoren, particularly the elderly keep a sharp lookout to eating egg, are afraid of to eat egg and cause that cholesterol increases and causes atherosclerotic.Scientists study is found, though contain more cholesterol in egg, also contains abundant lecithin simultaneously.Lecithin enters after blood, can make cholesterol and fatty particle diminish, and make it to keep suspended state, thereby stop cholesterol and the fatty deposition at vascular wall.Cholesterol is the important component of cell membrane, be that the mankind maintain normal physiological activity necessary, but in blood of human body, the too high meeting of cholesterol concentration causes high fat of blood, and then causes a series of angiocardiopathies such as hypertension, coronary heart disease.Egg is the nutraceutical that people are generally acknowledged, is the higher one of cholesterol level in animal food, average 213mg/ piece.The sick research association of american heart recommends human body cholesterol intake every day should not exceed 300mg, to reduce the danger of high fat of blood and coronary heart disease.Along with the enhancing of people's health care consciousness, people wish to take in less the food of high cholesterol count, thus, reduce egg cholesterol content and have important theoretical and practical significance.
A cholesterol part in laying hen body is directly entered in intestines through biliary system by liver, and becomes stercorin by enteric bacteria effect and excrete with ight soil; A part forms cyto-architectural composition in tissue; Most cholesterol proceed in yolk, excrete with the form of laying eggs.Egg cholesterol is almost all present in yolk, and every gram of yolk is on average containing cholesterol 13mg.Yolk moisture content 50% left and right, all the other major parts are protein and fat, protein and fatty ratio are about 1:2, fat mainly exists with lipoprotein form, as VLDL (VLDL) and lipovitellin, phosvitin etc., more than 95% cholesterol exists with VLDL form.The cholesterol of laying hen approximately synthetic 300mg every day, wherein approximately has 200mg to be deposited in yolk; 10mg cholesterol directly enters enteron aisle, excretes with ight soil.Yolk cholesterol is mainly derived from precursor-VLDL (VLDL) and vitellogenin (VTG) quantity of the synthetic yolk of liver, the quantity that cholesterol level of vitellus depends primarily on VLDL and enters egg mother cell.In blood, VLDL arrives after the egg mother cell of ovary, and the egg mother cell in the encytosis of receptor-mediated (OVR) is grown absorbs, and forms thus the dry of yolk 95% cholesterol and 60%.Meanwhile, vitellogenin arrives egg mother cell with same approach after synthetic, and the dry of 4% cholesterol and 24% is provided to yolk.
Raiser, in order to pursue market interest, widely applies the chemical synthetic drugs such as antibiotic, although can reduce the content of egg cholesterol, has also seriously reduced the quality of egg simultaneously, and higher drug residue affects the healthy of consumer.
Summary of the invention
In order to realize the cholesterol level that reduces laying hen egg, improve egg production and egg size, improve the object of the immunity of laying hen simultaneously, the embodiment of the present invention provides a kind of laying cycle of laying hens feed addictive and preparation method thereof.
In order to realize foregoing invention object, the invention provides a kind of laying cycle of laying hens feed addictive, described feed addictive comprises Chinese medicine additive, enzymatic compositions and neo dohyfral D3, and wherein, the ratio of weight and number of described Chinese medicine additive, enzymatic compositions and neo dohyfral D3 is 1:1:0.01-0.5; Described Chinese medicine additive comprises following raw medicinal material: marine alga, rhizoma atractylodis, Radix Codonopsis, caryophyllaceous ginseng, chrysanthemum, comfrey, pollen, Chinese scholartree leaf, the membrane of a chicken's gizzard, trifoliate orange, fructus amomi, Chinese yam, French beans, date, thizoma curculiginis, matrimony vine, walnut kernel, the seed of Chinese dodder, glutinous rice rhizome and root and maidenhair.
Described enzymatic compositions is one or more in zytase, 1,4 beta-glucanase, 'beta '-mannase, cellulase, amylase or protease; Described enzymatic compositions is preferably zytase, 1,4 beta-glucanase, 'beta '-mannase, cellulase, amylase and protease, and its ratio of weight and number is: 1:1:2:1:2:1.
In described Chinese medicine additive, the parts by weight of each raw medicinal material are preferably: marine alga 15-25 weight portion, rhizoma atractylodis 10-20 weight portion, Radix Codonopsis 15-25 weight portion, caryophyllaceous ginseng 10-15 weight portion, chrysanthemum 13-24 weight portion, comfrey 10-20 weight portion, pollen 10-20 weight portion, Chinese scholartree leaf 15-25 weight portion, the membrane of a chicken's gizzard 15-25 weight portion, trifoliate orange 10-18 weight portion, fructus amomi 10-16 weight portion, Chinese yam 10-20 weight portion, French beans 10-20 weight portion, date 10-20 weight portion, thizoma curculiginis 10-20 weight portion, matrimony vine 15-25 weight portion, walnut kernel 10-20 weight portion, seed of Chinese dodder 10-20 weight portion, glutinous rice rhizome and root 10-20 weight portion and maidenhair 10-15 weight portion.
In described Chinese medicine additive, the parts by weight of each raw medicinal material can also be preferably: marine alga 18 weight portions, rhizoma atractylodis 17 weight portions, Radix Codonopsis 19 weight portions, caryophyllaceous ginseng 13 weight portions, chrysanthemum 20 weight portions, comfrey 16 weight portions, pollen 15 weight portions, Chinese scholartree leaf 20 weight portions, the membrane of a chicken's gizzard 19 weight portions, trifoliate orange 14 weight portions, fructus amomi 13 weight portions, Chinese yam 15 weight portions, French beans 15 weight portions, date 17 weight portions, thizoma curculiginis 17 weight portions, matrimony vine 21 weight portions, walnut kernel 15 weight portions, the seed of Chinese dodder 15 weight portions, glutinous rice rhizome and root 15 weight portions and maidenhair 13 weight portions.
Described Chinese medicine additive also comprises: glossy ganoderma, barley, lotus leaf, dried orange peel and paniculate swallowwort.
In described Chinese medicine additive, the parts by weight of each raw medicinal material are preferably: marine alga 15-25 weight portion, rhizoma atractylodis 10-20 weight portion, Radix Codonopsis 15-25 weight portion, caryophyllaceous ginseng 10-15 weight portion, chrysanthemum 13-24 weight portion, comfrey 10-20 weight portion, pollen 10-20 weight portion, Chinese scholartree leaf 15-25 weight portion, the membrane of a chicken's gizzard 15-25 weight portion, trifoliate orange 10-18 weight portion, fructus amomi 10-16 weight portion, Chinese yam 10-20 weight portion, French beans 10-20 weight portion, date 10-20 weight portion, thizoma curculiginis 10-20 weight portion, matrimony vine 15-25 weight portion, walnut kernel 10-20 weight portion, seed of Chinese dodder 10-20 weight portion, glutinous rice rhizome and root 10-20 weight portion, maidenhair 10-15 weight portion, glossy ganoderma 15-25 weight portion, barley 10-18 weight portion, lotus leaf 10-15 weight portion, dried orange peel 10-20 weight portion and paniculate swallowwort 10-15 weight portion.
In described Chinese medicine additive, the parts by weight of each raw medicinal material can also be preferably: marine alga 21 weight portions, rhizoma atractylodis 15 weight portions, Radix Codonopsis 20 weight portions, caryophyllaceous ginseng 12 weight portions, chrysanthemum 16 weight portions, comfrey 15 weight portions, pollen 15 weight portions, Chinese scholartree leaf 18 weight portions, the membrane of a chicken's gizzard 22 weight portions, trifoliate orange 14 weight portions, fructus amomi 13 weight portions, Chinese yam 15 weight portions, French beans 15 weight portions, date 15 weight portions, thizoma curculiginis 15 weight portions, matrimony vine 19 weight portions, walnut kernel 15 weight portions, the seed of Chinese dodder 15 weight portions, glutinous rice rhizome and root 15 weight portions, maidenhair 12 weight portions, glossy ganoderma 20 weight portions, barley 14 weight portions, lotus leaf 13 weight portions, dried orange peel 15 weight portions and paniculate swallowwort 13 weight portions.
In order better to realize foregoing invention object, the invention provides a kind of preparation method of laying cycle of laying hens feed addictive, described preparation method comprises the following steps:
The first step, mixes above-mentioned various raw medicinal materials by ratio of weight and the number of copies, and input pulverizer is pulverized or directly chopping, pack into and decoct in container, add suitable quantity of water to make its submergence medicinal material, soak after 30-60 minute, be heated to seethe with excitement after 30-60 minute, separate fried liquid, the dregs of a decoction again add water and decoct 2-3 time, isolate respectively fried liquid at every turn, merge all fried liquid, after filtering, get filtrate and abandon filter residue again;
Second step, after filtrate is cooling, adding with respect to liquid weight 1-2 determining alcohol doubly after concentrated is 80-90% ethanol, fully mix, placement is spent the night, and makes its precipitation, after getting its supernatant liquid filtering next day, obtain filtrate, the ethanol that sediment is 50-60% with determining alcohol is cleaned, and collects washing lotion and merges with filtrate, decompression is regained after ethanol, leave standstill 0.5-1 hour, make precipitation completely, filter, filtrate low-temperature evaporation, obtains paste;
The 3rd step: paste is put into spray dryer dry, ensure that EAT is at 180 DEG C-200 DEG C, 70 DEG C-90 DEG C of leaving air temps, are ground into 200 order-300 orders subsequently, obtain Chinese medicine additive pulvis;
The 4th step: by weight Chinese medicine additive, enzymatic compositions and neo dohyfral D3 are mixed and obtain feed addictive.
The present invention also provides a kind of laying cycle of laying hens Chinese medicine additive, described Chinese medicine additive is made up of the raw medicinal material of following parts by weight: marine alga 15-25 weight portion, rhizoma atractylodis 10-20 weight portion, Radix Codonopsis 15-25 weight portion, caryophyllaceous ginseng 10-15 weight portion, chrysanthemum 13-24 weight portion, comfrey 10-20 weight portion, pollen 10-20 weight portion, Chinese scholartree leaf 15-25 weight portion, the membrane of a chicken's gizzard 15-25 weight portion, trifoliate orange 10-18 weight portion, fructus amomi 10-16 weight portion, Chinese yam 10-20 weight portion, French beans 10-20 weight portion, date 10-20 weight portion, thizoma curculiginis 10-20 weight portion, matrimony vine 15-25 weight portion, walnut kernel 10-20 weight portion, seed of Chinese dodder 10-20 weight portion, glutinous rice rhizome and root 10-20 weight portion, maidenhair 10-15 weight portion, glossy ganoderma 15-25 weight portion, barley 10-18 weight portion, lotus leaf 10-15 weight portion, dried orange peel 10-20 weight portion and paniculate swallowwort 10-15 weight portion.
In order better to realize foregoing invention object, the invention provides a kind of preparation method of laying cycle of laying hens feed addictive, described preparation method comprises the following steps:
The first step, mixes various raw medicinal materials by ratio of weight and the number of copies, and input pulverizer is pulverized or directly chopping, pack into and decoct in container, add suitable quantity of water to make its submergence medicinal material, soak after 30-60 minute, be heated to seethe with excitement after 30-60 minute, separate fried liquid, the dregs of a decoction again add water and decoct 2-3 time, isolate respectively fried liquid at every turn, merge all fried liquid, after filtering, get filtrate and abandon filter residue again;
Second step, after filtrate is cooling, adding with respect to liquid weight 1-2 determining alcohol doubly after concentrated is 80-90% ethanol, fully mix, placement is spent the night, and makes its precipitation, after getting its supernatant liquid filtering next day, obtain filtrate, the ethanol that sediment is 50-60% with determining alcohol is cleaned, and collects washing lotion and merges with filtrate, decompression is regained after ethanol, leave standstill 0.5-1 hour, make precipitation completely, filter, filtrate low-temperature evaporation, obtains paste;
The 3rd step: paste is put into spray dryer dry, ensure that EAT is at 180 DEG C-200 DEG C, 70 DEG C-90 DEG C of leaving air temps, are ground into 200 order-300 orders subsequently, obtain Chinese medicine additive pulvis.
The beneficial effect that the technical scheme that the embodiment of the present invention provides is brought is: feed addictive of the present invention contains Chinese medicine additive, there is effect of invigorating the spleen to dry, invigorating the kidney and spleen, with other raw material matcheds, not only can reduce the cholesterol level of laying hen egg, improve laying rate and the egg size of laying hen, but also can improve the resistance against diseases of laying hen.
Detailed description of the invention
The invention provides a kind of feed addictive that contains Chinese medicine additive, wherein Chinese medicine additive comprises following raw medicinal material: marine alga, rhizoma atractylodis, Radix Codonopsis, caryophyllaceous ginseng, chrysanthemum, comfrey, pollen, Chinese scholartree leaf, the membrane of a chicken's gizzard, trifoliate orange, fructus amomi, Chinese yam, French beans, date, thizoma curculiginis, matrimony vine, walnut kernel, the seed of Chinese dodder, glutinous rice rhizome and root and maidenhair; Preferably, Chinese medicine additive also comprises: glossy ganoderma, barley, lotus leaf, dried orange peel and paniculate swallowwort.
In Chinese herb feed additive, the pharmacology of each raw medicinal material is as follows:
Marine alga: bitter, salty, cold in nature, nontoxic.Gui Jing: lung; Spleen; Kidney; Liver stomach is through effect: soft heavily fortified point; Dissolving phlegm; Li Shui; Detumescence.Thyroid gland enlargement, an inferior gluteal lymph node tuberculosis.Dissipating bind gas carbuncle is swollen, abdomen inner product piece, distending pain, the ring of abdomen hollow.Also can descend 12 kinds of oedema, treat between skin and gather sudden and violent bursting, stay depressed heat, diuresis.Cure mainly: scrofula; Goiter and tumor; Gather; Oedema; Beriberi; Testiclar gall; (Epileptic is ruined) hernia." Haiyao Bencao, Oversea Materia Medica " records it: " main place food does not disappear, and five phlegm of separating are stopped up, aqueous vapor edema, beriberi, up-rushing gas syndrome ".Marine alga contains a kind of special protein and is called close glycoprotein, and it has compatibility and non-covalent combination with it to certain sugars.After parent's glycoprotein and the combination of cell membrane glycan molecule, can cause cell settlement phenomenon, be therefore a kind of agglutinin.Parent's glycoprotein is prevalent in land animals and plants and microorganism, especially abundant especially in seeds of leguminous plant.The characteristic of its identification carbohydrate of parent's glycoprotein mat is played an important role on biological defence, growth, reproduction, nutrition storage and biocenosis.Parent's glycoprotein also can be applicable to blood cell and separates detection, on the generation of pharmaceutical carrier, immune antiboidy and the medical usage of cancer therapy drug.
Rhizoma atractylodis: nature and flavor are pungent, bitter, temperature.Return spleen, stomach, Liver Channel.Cure mainly: the transporting imbalance that the spleen being blocked by dampness causes, poor appetite, vomiting is unhappy, and abdominal distension is had loose bowels, arthralgia.For dampness taste, abdominal fullness and distention, cold-dampness leukorrhea, damp-warm diseases and damp invasion of lower energizer, pin swelling and pain in knee, impotence are soft unable.Control dampness taste, and see the thick disease such as turbid of abdominal fullness and distention, poor appetite, lassitude hypodynamia, white and greasy fur, the compatibilities such as normal and the bark of official magnolia, dried orange peel are applied; Control cold-dampness leukorrhea, can join the root of Dahurain angelica with using.As damp and hot leukorrhea, can join again the wind-weed, kuh-seng, Patrinia heterophylla; Damp invasion of lower energizer, pin swelling and pain in knee, impotence are soft unable, can join golden cypress, the root of bidentate achyranthes, coix seed and be equal to use; Damp-warm syndrome disease can be joined gypsum and is equal to use.Rhizoma atractylodis have drying damp and strengthening spleen, effect of wines used as antirheumatic.Cure mainly damp retention in middle-jiao, wind-cold-dampness arthralgia, pin swelling and pain in knee, impotence is soft unable, night blindness yctalopia." pearl sac " day: " can stomach invigorating pacify spleen, all wet swollen non-these can not remove." Compendium of Material Medica says: " control wet phlegm and stay drink ... and spleen is wet dirty, under turbid drop band, the sliding intestines wind that rushes down." " Tang materia medica " claim that it can " diuresis ".
Radix Codonopsis: Codonopsis plant.The whole world approximately has 40 kinds, and China approximately has 39 kinds, and medicinal have 21 kinds, 4 mutation.Chinese medicine Radix Codonopsis is Campanulaceae herbaceos perennial Radix Codonopsis, element flower Radix Codonopsis, radix codonpsis tangshen and the root that belongs to various plants together thereof.Radix Codonopsis is the conventional traditional tonic of China, and the Radix Codonopsis that produce ancient times taking area, Shangdang, Shanxi, as top grade, has tonifying middle-Jiao and Qi, effect of invigorating the spleen benefit lung.Modern study, Radix Codonopsis, containing various saccharides, phenols, sterol, volatile oil, scutellarein glucosid, saponin and Alkaloid, has immunity, hemangiectasis, the step-down of enhancing, improves microcirculation, strengthens the effects such as hematopoiesis function.In addition leucocyte chemotherapy radiotherapy being caused declines castering action.Radix Codonopsis has tonifying middle-Jiao and Qi, effect of invigorating the spleen benefit lung.For a little less than the spleen deficiency syndrome of the lung, the palpitaition of breathing hard, anorexia and loose stool, void is breathed with cough and is coughed, and interior heat is quenched one's thirst etc." new compilation of materia medica " recorded: " tonifying middle-Jiao and Qi and taste, relieving thirst and restlessness.Middle gas is faint, mends in order to adjust, very smooth and proper." impact on digestive system: adjust the key medicine that gastrointestinal motility function Radix Codonopsis is tonifying middle-Jiao and Qi, can correct the gastrointestinal motility dysfunction of pathological state.By the method for chronic heeling-in stomach electrode, observing Radix Codonopsis water decoction-alcohol sedimentation liquid has regulating action to rat stomach basic electric rhythm disorder under stress situation, and can partly resist the stomach motion that stress cause increases and rapid gastric emptying.Asiabell preparation intravenous injection is wriggled to normal rat stomach or is all had inhibitory action with the peristole that neostigmine has strengthened, and shows as that peristaltic wave amplitude reduces, frequency deceleration.Radix Codonopsis decocting liquid can improve mouse III degree and scald hindgut power function obstacle, significantly improves little alvine pushing rate.Radix Codonopsis liquid has and suppresses and excited two kinds of effects isolated guinea pig ileum, can make tensile force of ileum raise or first fall rear liter, Frequency downshift, and can maintain the long period, and acetylcholine and 5-HT are caused to ileum contraction has obvious antagonism.Antiulcer action Radix Codonopsis water decoction-alcohol sedimentation liquid to stress type, Experimental Gastric Ucler all has preventive and therapeutic action due to pyloric ligation ulcers, indocin or aspirin.Through experiment relatively, with Radix Codonopsis just the good effect of the neutral extract of alcohol to stress ulcer, ulcer inhibition rate can reach 98 %, it is 72.9% that water extract takes second place, ligroin extraction effect is the poorest.Radix Codonopsis water soluble part VII extract can resist by gastric mucosa damage and gastric ulcer due to absolute ethyl alcohol, strong acid (0.6NHCI) and highly basic (0.2NNaOH) etc.Radix Codonopsis has inhibitory action to rat basal gastric acid secretion, can reduce pepsin activity, and resist aspirin caused hydrochloric acid in gastric juice and increase, indocin, aspirin caused gastric mucosa PGE2 (PGE2) and amidohexose content are declined and also has inhibitory action.
Caryophyllaceous ginseng: sweetness and bitterness is flat, enters spleen, lung channel.Function: nourishing generate fluid.For impairment of both QI and YIN after being ill, the spontaneous perspiration of losing heart, poor appetite, the disease such as dry is thirsty, deficiency of Yin cough caused by dryness.
Chrysanthemum: cold nature, bitter, pungent." book on Chinese herbal medicine converges and says ": " broken blood is soothing the liver, separates the loose poison of malignant boil.Place blood in housewife people's abdomen, the malicious red malignant boil of the capable fire of Xie Tian.Wash sore scabies, can remove again wind desinsection." function is clearing heat and detoxicating, detumescence.To staphylococcus aureus, corynebacterium diphtheriae, streptococcus, Pseudomonas aeruginosa, puncture Shigella, influenza virus, all there is inhibitory action.To furunculosis, ulcer, erysipelas, eczema, dermatitis, anemopyretic cold, abscess of throat, high blood pressures etc. have good curative effect.
Comfrey: comfrey is the animal and fowl fodder plant of good quality and high output, once plantation can utilize more than 20 year continuously.Through planting the herbage comparison of planting and feed with clover, string leaf prairie dock etc. more than 20, comfrey has three unique large economic traits, and the one, grass yield is high, and power of regeneration is strong.Spring, summer, Qiu Sanji can be with cutting with length, and a growth season north can cradle 3 times～4 times, and south can cradle 4 times～6 times.0.4 ten thousand kilograms～0.5 ten thousand kilograms of the fresh careless output of general every batch of mu are the high quality forage kinds of high yield in Chinese all kinds of herbage.The 2nd, good palatability, digestibility is high.The blue or green tender succulence of comfrey branches and leaves, fragrant odour, quality jewelry, expensive clothing and other valuables.Green grass gives out light cucumber fragrance after chopping or making beating, pig, ox, sheep, rabbit, chicken, duck, and goose, ostrich, phytophage fish are all liked food, and can significantly promote to hold growing of fowl.Comfrey is rich in protein and vitamin, is of high nutritive value, and the content of various nutritional labelings and digestibility thereof are all higher than general herbage.Through inspection, in comfrey fresh careless dry in florescence, contain thick protein 24.3%, crude fat 5.9%, crude fibre 10.1%.In addition, it also contains a large amount of allantoins and cobalamin, can prevent and treat domestic animal and fowl's enteritis, after livestock food, does not have loose bowels.
Pollen: be rich in several amino acids, protein, vitamin and bioactivator, can dispel again various pigment spots, have adjusting nervous system, promote sleep, build up health; Improve functions of intestines and stomach, promote digestion, whet the appetite, effect of control habitual constipation.Effect of zasiokaurin: cholagogic detumescence, removing jaundice, sharp blood, diuresis, hypotensive, and to the human body renal function suitable curative effect of strengthening the body resistance to consolidate the constitution.Can prophylactic treatment nephritic dropsy, renal shutdown, cholecystitis, gall stone, jaundice type hepatitis, hypotensive, hypertrophy of the prostate, prostatitis, specially control andropathy.
Chinese scholartree leaf: control frightened epilepsy, high fever, intestines wind, haematuria, hemorrhoid, mange, eczema, malignant boil is swollen.There is antiinflammatory action, antivirus action.
The membrane of a chicken's gizzard: taste is sweet, cold in nature, enter spleen, stomach, small intestine, urinary bladder channel, there are reinforcing spleen to promote digestion, puckery essence to stop excessive effect, are mainly used in the abdominal fullness and distention of dyspepsia stagnation, heating installation diarrhoea, the symptoms such as children's's infantile malnutrition due to digestive disturbances or intestinalparasites disease, the membrane of a chicken's gizzard can promote gastric secretion, strengthens peristole, accelerate the effects such as gastric emptying.
Trifoliate orange: taste is sweet, cold in nature, enter spleen, stomach, small intestine, urinary bladder channel, there are reinforcing spleen to promote digestion, puckery essence to stop excessive effect, are mainly used in the abdominal fullness and distention of dyspepsia stagnation, heating installation diarrhoea, the symptoms such as children's's infantile malnutrition due to digestive disturbances or intestinalparasites disease, the membrane of a chicken's gizzard can promote gastric secretion, strengthens peristole, accelerate the effects such as gastric emptying.
Fructus amomi: be Perenniporia martius zingiberaceous plant fruits and seeds, be the conventional medicinal material of armaticity simply of the traditional Chinese medical science.The Ji Yuan of at present medicinal fructus amomi mainly contains three kinds: a kind of is mainly to originate in the spring sand that Chinese Guangdong is economized; A kind of is the shell sand in Chinese Hainan; Also have one to be Amomum xanthioides, main product is in country in Southeast Asia.Wherein, the curative effect that spring sand (fruit) is used as medicine is more remarkable, and quality is also relatively good, on international medicinal material market, enjoys higher reputation.The traditional Chinese medical science thinks, fructus amomi Main Function is in stomach, kidney and the spleen of human body, can promoting the circulation of qi seasoning, and stomach is amusing.
Chinese yam: tonifying spleen nourishing the stomach, the beneficial lung that promotes the production of body fluid, the puckery essence of kidney tonifying.Few for insufficiency of the spleen food, endless diarrhea, the deficiency syndrome of the lung is breathed with cough, emission due to the kidney deficiency, under band, frequent micturition, abnormal heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) tonifying spleen stomach invigorating.Few for insufficiency of the spleen food, the loose stool of having loose bowels, leukorrhea.This product yin-nourishing can help wet, in containing so wet full or have stagnant, have real evil person unsuitable.Need to remind everybody, edible Chinese yam is general without obvious contraindication, but because it has astriction, so catch a cold, dry feces person and the stagnant person of stomach avoid use.
French beans: sweet, flat.Enter spleen, stomach warp.Cure mainly tonic the five internal organs, preventing or arresting vomiting is told.Take for a long time, can make hair not white.Can separate the poison of all vegetations, after boiling, chew to eat with liquor and drink, all effective.Make general mood in human body current, control woman's leukorrhea, again can relieving alcoholism, the poison of globe fish.Can cure dysentery, eliminate hot summer weather, warm taste, except remuval of damp and hot, only quench one's thirst.Grind into powder together with vinegar and take down, can treat cholera vomiting and diarrhoea more than." detailed outline " cloud: " duricrust Semen Lablab Album, its son enriches, Bai Erwei Huang, its gas raw meat perfume (or spice), it is warm in nature flat, obtains neutralization, and the paddy of spleen is also.Enter lunar gas and divide, tonneau three warmers, can change fall clearly turbid, therefore specially control the disease of Middle Palace, relieve summer heat dehumidifying and removing toxic substances also.Its soft shell and black magpie look person, its slightly cool in nature, but can be for food, also adjust taste.”
Date: the CAMP that red date is contained is the essential composition of human body cell energetic supersession, can strengthen muscular strength, eliminates fatigue, hemangiectasis, increase myocardial contractive power, improve myocardial nutrition, has good effect to preventing and treating disease of cardiovascular system; Traditional Chinese medicine theory thinks, red date has the effects such as qi-restoratives benefit gas, nourishing blood and tranquilization, strengthening the spleen and stomach, and red date has good therapeutic effect to illnesss such as chronic hepatitis, cirrhosis, anaemia, anaphylactoid purpuras; Red date contains triterpene compound and CAMP, has stronger anticancer, anti-allergic effects.Date can moisten cardiopulmonary, cough-relieving, tonifying five zang organs, it is deficient to control, except stomach addiction gas, in can also pacifying, support spleen, flat stomach Qi, logical nine orifices, help 12 through etc.
Thizoma curculiginis: pungent, temperature, poisonous.Enter kidney, Liver Channel.Kidney-replenishing, strengthening the bones and muscles, loose cold-dampness.Control impotence cold sperm, aconuresis, uterine bleeding, trusted subordinate's crymodynia, cold arthralgia of loins and legs, ulcer, scrofula, the deficiency of yang is cold rushes down.The diseases such as impotence essence is cold, and waist knee is air-cooled, muscles and bones impotence numbness.Modern pharmacology activity research show thizoma curculiginis have regulate immune, anti-oxidant, protect the liver, the effect such as antihyperglycemic, tonifying kidney and strengthening yang and anti-osteoporosis, anti-inflammatory and adaptation former state.Research shows: thizoma curculiginis can be improved the reactivity of removal ovary anesthetized rat hypophysis to injection luteinizing hormone-releasing hormone (LRH) (LRH); Improve the reactivity of ovary to lutropin in blood plasma (LH), thereby play the effect that improves sexual function.Thizoma curculiginis decoction gavage, can make anterior pituitary of rat weight, ovary weight and uterus weight obviously increase, ovary HCG/LH receptor-specific adhesion is increased, but on lutropin in blood plasma (LH) level without impact. experiment show: curculigol preserved material 10g/kg/d is the rat oral gavage after 7 days to castration, continuous 21 days, castrated rats weight of seminal vesicle obviously increases, and points out it to have the effect of male sex hormone sample.Thizoma curculiginis aqueous extract has the effect of excitability function.
Matrimony vine: modern study, the fruit of Chinese wolfberry has the blood sugar of reduction, lipotropy, and can antiatherosclerosis.The fruit of Chinese wolfberry is also for strengthening the body resistance to consolidate the constitution, and the good medicine that production of sperm is mended marrow, enriching yin and nourishing kidney, benefiting qi for tranquillization, improved the health, delays senility is evident in efficacy to chronic hepatitis, central retinitis, optic atrophy etc.; Diabetes, pulmonary tuberculosis etc. are also had to good therapeutic effect; To antitumor, protect the liver, step-down, ageing disorders hypoglycemic and the elderly's organ failure have very strong improvement effect.As tonic invigorator treatment suffer from a deficiency of the kidney each disease and liver and kidney disease curative effect excellent, can significantly improve plasma testosterone cellulose content in human body, reach the effect of keeping fit.Modern medicine study shows, matrimony vine has obvious inhibitory action to cancer cell in vitro, the immunologic function that can be used for preventing the diffusion of cancer cell and strengthen human body.
Walnut kernel: sweet, temperature.Return kidney, lung, large intestine channel.Function cures mainly: kidney tonifying, warm lung, ease constipation.For soreness and weakness of waist and knees, impotence and seminal emission, the cold of insufficiency type is breathed heavily and is coughed, constipation.
The seed of Chinese dodder: Gan Xinping, enters liver, kidney channel.Tonifying kidney and benefiting sperm, nourishes the liver to improve visual acuity, antiabortive.For caused by liver and kidney deficiency, soreness of waist and knee joint, impotence and seminal emission, frequent urination and enuresis, two blurred visions are dark, the diseases such as fetal irritability.Function tonification liver kidney, controlling nocturnal emission with astringent drugs contracting urine, antiabortive, improving eyesight, antidiarrheal.Suffer from a deficiency of the kidney and rush down for impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness and weakness of waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, fetal irritability, spleen.
Glutinous rice rhizome and root: sweet, flat.Enter liver, lung, kidney three warps.Function cures mainly: reinforcing stomach reg fluid, reducing the asthenic fever, only night sweat.1. " book on Chinese herbal medicine is new again ": " tonifying Qi is reduced phlegm, and stomach is strengthened in enriching yin, except rheumatism.Control cold sensation of the genitalia, antiabortive and blood, treats pernio, metal-inflicted wound." 2. " Chinese medicine voluminous dictionary ": " nourishing the stomach, clearing lung-heat, invigorating the spleen, reducing the asthenic fever." 3. " medicinal material data compilation ": " be night sweat only." 4. " pharmacognosy ": " tonifying lung invigorating the spleen, nourishing the stomach Tianjin."
Maidenhair: hardship, flat.Function cures mainly: clearing heat and promoting diuresis, cough-relieving, pain relieving.For the infection of the upper respiratory tract, dysentery, cough, pertussis, toothache, acute conjunctivitis due to pathogenic wind-fire; Mumps is controlled in external application, mastitis.
Glossy ganoderma: property is sweet, flat.The thoughts of returning home, lung, liver, kidney channel.Cure mainly consumptive disease, cough, asthma, insomnia, indigestion, malignant tumour etc.Animal pharmacology shows experiment: glossy ganoderma has inhibitory action to nervous system, and the circulatory system has step-down and strengthens the effect of cardiac contractile force, and respiratory system is had to phlegm-dispelling functions, in addition, protects in addition liver, improves immunologic function, antibacterially waits effect.
Barley: Gan Xian is cool.Enter spleen, stomach two warps.Function cures mainly: and stomach, wide intestines, Li Shui.Control stagnant the having loose bowels of food, urine leaching pain, oedema, burn.
Lotus leaf: hardship, flat.Return liver, spleen, stomach warp.Function cures mainly: clearing away summerheat, sending up the lucid yang, cooling blood and hemostasis.For hot summer weather polydipsia, summer heat damp diarrhea, splenasthenic diarrhea, blood-head is told nosebleed, the uterine bleeding of having blood in stool.Burnt FOLIUM NELUMBINIS inducing astrigency removing blood stasis and hemostasis.For multiple haemorrhage and postpartum anemic fainting.
Dried orange peel: regulating the flow of Qi and the middle Jiao, eliminating dampness and eliminating phlegm, sharp water defaecation.Cure mainly incoordination between the spleen and the stomach, abdominal distention, do not feel like eating, vomiting hiccup; Phlegm-damp obstructing lung, coughing with a lot of sputum, chest diaphragm is full vexed, vertigo; Oedema, difficult urination, constipation; Acute mastitis sore tinea, middle fish crab poison, wine poison.For diseases such as fullness and oppression of chest and abdomen.The pungent loose logical temperature of orange peel, fragrant odour, is longer than and regulates the flow of vital energy, and can enter spleen lung, therefore can go loose sluggishness of lung-QI, again can promoting the circulation of qi wide in, for lung qi gather around stagnant, chest diaphragm ruffian full and the disease such as the taste stagnation of the circulation of vital energy, abdominal fullness and distention.Temperature eliminating dampness and can invigorating the spleen promoting the circulation of qi, therefore be usually used in the diseases such as damp retention in middle-jiao, gastral cavity abdominal distension is vexed, loose stool tongue is greasy, can compatibility rhizoma atractylodis, the bark of official magnolia is with using.Be good at again eliminating dampness and eliminating phlegmly, stop up the conventional key medicines of lung, the many coughs of phlegm for controlling wet phlegm, every with the tuber of pinellia, Poria cocos with use.For insufficiency of the spleen diet reduce, indigestion, and the disease such as n and V, eliminating dampness and can spleen benefiting and stimulating the appetite, is applicable to the diseases such as weakness of the spleen and the stomach, diet minimizing, indigestion, stool diarrhea, the fit applications such as normal and ginseng, the bighead atractylodes rhizome, Poria cocos.Can invigorating the spleen because of it, can regulate the flow of vital energy again, therefore often make as the assistant of Qi-tonifying drug, can make tonify without causing stagnation, prevent from stopping up the swollen effect of doing of holding back.In addition, orange peel again can with in, can control stomach Qi rising, n and V.
Paniculate swallowwort: warm in nature, taste is pungent; Dispelling wind is antipyretic, and the promoting flow of qi and blood circulation cures mainly: analgesia, cough-relieving, inducing diuresis for removing edema, promoting blood circulation and detoxication.Treat for stomachache, toothache, rheumatalgia pain, bellyache in menstrual period, chronic bronchitis, ascites, oedema, dysentery, enteritis, traumatic injury, eczema, nettle rash, venomous snake bite.What is fed and raised rabbit experiment hyperlipemia and the experimental atherosclerosismodel that cholesterol diet causes, paniculate swallowwort has the effect that reduces serum total cholesterol and beta lipoprotein, and can alleviate atherosclerosis of aorta and parteriole lipid deposition, thereby show that paniculate swallowwort has preventive and therapeutic effect to atherosclerotic.
Embodiment 1 feed addictive 1
The embodiment of the present invention provides a kind of feed addictive, is made up of following raw material: Chinese medicine additive, enzymatic compositions and neo dohyfral D3, and wherein, the ratio of weight and number of Chinese medicine additive, enzymatic compositions and neo dohyfral D3 is 1:1:0.03;
Wherein, in Chinese medicine additive, the parts by weight of each raw medicinal material are: marine alga 18 weight portions, rhizoma atractylodis 17 weight portions, Radix Codonopsis 19 weight portions, caryophyllaceous ginseng 13 weight portions, chrysanthemum 20 weight portions, comfrey 16 weight portions, pollen 15 weight portions, Chinese scholartree leaf 20 weight portions, the membrane of a chicken's gizzard 19 weight portions, trifoliate orange 14 weight portions, fructus amomi 13 weight portions, Chinese yam 15 weight portions, French beans 15 weight portions, date 17 weight portions, thizoma curculiginis 17 weight portions, matrimony vine 21 weight portions, walnut kernel 15 weight portions, the seed of Chinese dodder 15 weight portions, glutinous rice rhizome and root 15 weight portions and maidenhair 13 weight portions.
Enzymatic compositions is made up of zytase, 1,4 beta-glucanase, 'beta '-mannase, cellulase, amylase and protease, and its ratio of weight and number is: 1:1:2:1:2:1.
The preparation method of feed addictive comprises the following steps:
The first step, mixes above-mentioned various raw medicinal materials by ratio of weight and the number of copies, and input pulverizer is pulverized or directly chopping, pack into and decoct in container, add suitable quantity of water to make its submergence medicinal material, soak after 50 minutes, be heated to seethe with excitement after 50 minutes, separate fried liquid, the dregs of a decoction again add water and decoct 2 times, isolate respectively fried liquid at every turn, merge all fried liquid, after filtering, get filtrate and abandon filter residue again;
Second step, after filtrate is cooling, adding with respect to the determining alcohol of 2 times of liquid weights after concentrated is 80-90% ethanol, fully mix, placement is spent the night, and makes its precipitation, after getting its supernatant liquid filtering next day, obtain filtrate, the ethanol that sediment is 55% with determining alcohol is cleaned, and collects washing lotion and merges with filtrate, decompression is regained after ethanol, leave standstill 40 minutes, make precipitation completely, filter, filtrate low-temperature evaporation, obtains paste;
The 3rd step: paste is put into spray dryer dry, ensure that EAT is at 180 DEG C, 90 DEG C of leaving air temps, are ground into 200 order orders subsequently, obtain Chinese medicine additive pulvis;
The 4th step: by weight Chinese medicine additive, enzymatic compositions and neo dohyfral D3 are mixed and obtain feed addictive.
Embodiment 2 feed addictives 2
The embodiment of the present invention provides a kind of feed addictive, is made up of following raw material: Chinese medicine additive, enzymatic compositions and neo dohyfral D3, and wherein, the ratio of weight and number of Chinese medicine additive, enzymatic compositions and neo dohyfral D3 is 1:1:0.05;
Wherein, in Chinese medicine additive, the parts by weight of each raw medicinal material are: marine alga 21 weight portions, rhizoma atractylodis 15 weight portions, Radix Codonopsis 20 weight portions, caryophyllaceous ginseng 12 weight portions, chrysanthemum 16 weight portions, comfrey 15 weight portions, pollen 15 weight portions, Chinese scholartree leaf 18 weight portions, the membrane of a chicken's gizzard 22 weight portions, trifoliate orange 14 weight portions, fructus amomi 13 weight portions, Chinese yam 15 weight portions, French beans 15 weight portions, date 15 weight portions, thizoma curculiginis 15 weight portions, matrimony vine 19 weight portions, walnut kernel 15 weight portions, the seed of Chinese dodder 15 weight portions, glutinous rice rhizome and root 15 weight portions, maidenhair 12 weight portions, glossy ganoderma 20 weight portions, barley 14 weight portions, lotus leaf 13 weight portions, dried orange peel 15 weight portions and paniculate swallowwort 13 weight portions.
Enzymatic compositions is made up of zytase, 1,4 beta-glucanase, 'beta '-mannase, cellulase, amylase and protease, and its ratio of weight and number is: 1:1:2:1:2:1.
The preparation method of feed addictive comprises the following steps:
The first step, mixes above-mentioned various raw medicinal materials by ratio of weight and the number of copies, and input pulverizer is pulverized or directly chopping, pack into and decoct in container, add suitable quantity of water to make its submergence medicinal material, soak after 40 minutes, be heated to seethe with excitement after 40 minutes, separate fried liquid, the dregs of a decoction again add water and decoct 3 times, isolate respectively fried liquid at every turn, merge all fried liquid, after filtering, get filtrate and abandon filter residue again;
Second step, after filtrate is cooling, adding with respect to the determining alcohol of 2 times of liquid weights after concentrated is 80-90% ethanol, fully mix, placement is spent the night, and makes its precipitation, after getting its supernatant liquid filtering next day, obtain filtrate, the ethanol that sediment is 60% with determining alcohol is cleaned, and collects washing lotion and merges with filtrate, decompression is regained after ethanol, leave standstill 40 minutes, make precipitation completely, filter, filtrate low-temperature evaporation, obtains paste;
The 3rd step: paste is put into spray dryer dry, ensure that EAT is at 190 DEG C, 80 DEG C of leaving air temps, are ground into 250 orders subsequently, obtain Chinese medicine additive pulvis;
The 4th step: by weight Chinese medicine additive, enzymatic compositions and neo dohyfral D3 are mixed and obtain feed addictive.
Embodiment 3 Chinese medicine additives
The embodiment of the present invention also provides a kind of laying cycle of laying hens Chinese medicine additive, raw medicinal material by following parts by weight forms: marine alga 25 weight portions, rhizoma atractylodis 20 weight portions, Radix Codonopsis 15 weight portions, caryophyllaceous ginseng 10 weight portions, chrysanthemum 13 weight portions, comfrey 20 weight portions, pollen 20 weight portions, Chinese scholartree leaf 25 weight portions, the membrane of a chicken's gizzard 15 weight portions, trifoliate orange 18 weight portions, fructus amomi 16 weight portions, Chinese yam 10 weight portions, French beans 10 weight portions, date 20 weight portions, thizoma curculiginis 20 weight portions, matrimony vine 15 weight portions, walnut kernel 10 weight portions, the seed of Chinese dodder 10 weight portions, glutinous rice rhizome and root 20 weight portions, maidenhair 10 weight portions, glossy ganoderma 25 weight portions, barley 18 weight portions, lotus leaf 15 weight portions, dried orange peel 20 weight portions and paniculate swallowwort 15 weight portions.
Its preparation method comprises the following steps:
The first step, mixes various raw medicinal materials by ratio of weight and the number of copies, and input pulverizer is pulverized or directly chopping, pack into and decoct in container, add suitable quantity of water to make its submergence medicinal material, soak after 45 minutes, be heated to seethe with excitement after 45 minutes, separate fried liquid, the dregs of a decoction again add water and decoct 2 times, isolate respectively fried liquid at every turn, merge all fried liquid, after filtering, get filtrate and abandon filter residue again;
Second step, after filtrate is cooling, adding with respect to the determining alcohol of 2 times of liquid weights after concentrated is 80-90% ethanol, fully mix, placement is spent the night, and makes its precipitation, after getting its supernatant liquid filtering next day, obtain filtrate, the ethanol that sediment is 55% with determining alcohol is cleaned, and collects washing lotion and merges with filtrate, decompression is regained after ethanol, leave standstill 45 minutes, make precipitation completely, filter, filtrate low-temperature evaporation, obtains paste;
The 3rd step: paste is put into spray dryer dry, ensure that EAT is at 190 DEG C, 80 DEG C of leaving air temps, are ground into 250 orders subsequently, obtain Chinese medicine additive.
Toxicity test
Acute toxicity test: 40 of application NIH mouse, SPF level, male and female half and half, body weight 18～22g, carries out acute toxicity test.Mouse is divided into two groups at random, and 20 every group, i.e. control group and administration group, fasting 12 hours before experiment; Chinese medicine additive prepared by embodiments of the invention 3 is dissolved in water, (concentration is 6.58g crude drug/ml, maximum concentration) gavage, gavage volume is that 5ml/kg(is that single-dose dosage is 32.9 crude drugs/kg), control group gives equivalent physiological saline, administration in a day 2 times, delivery time 6 hours, Continuous Observation 14 days after administration, and record mouse toxic reaction and death toll.Experimental result shows: with control group comparison, after administration, mouse has no notable difference, experiment Continuous Observation 14 days, and mouse overall health of patients, diet, drinking-water, body weight gain are all normal.Therefore the Chinese medicine additive acute toxicity of the embodiment of the present invention 3 is low, clinical drug safety.Respectively the Chinese medicine additive of the embodiment of the present invention 1 and embodiment 2 is tested according to above-mentioned test method, the results show, the Chinese medicine additive acute toxicity of the embodiment of the present invention 1 and embodiment 2 is low, clinical drug safety.
Long term toxicity test: the Chinese medicine additive of the embodiment of the present invention 3 to mouse by 10.78,20.35 and 16 weeks (1.0ml/100g body weight of 33.48g crude drug/kg continuous use, every day 2 times) and drug withdrawal after 4 weeks, result shows: the index such as the hair of Chinese medicine of the present invention to mouse, behavior, stool and urine, body weight, organ weights, blood picture, hepatic and renal function, blood sugar, blood fat all has no significant effect, internal organs naked eyes do not find that difference changes and histological examination result shows, medication 16 weeks and drug withdrawal are after 4 weeks, and Organs of Mice is all without obviously changing.The Chinese medicine additive that the embodiment of the present invention 3 is described to mouse long-term prescription after toxicity little, after drug withdrawal, there is no difference reaction, application safety yet.Respectively the Chinese medicine additive of the embodiment of the present invention 1 and embodiment 2 is tested according to above-mentioned test method, result shows: the index such as the hair of the Chinese medicine additive of the embodiment of the present invention 1 and embodiment 2 to mouse, behavior, stool and urine, body weight, organ weights, blood picture, hepatic and renal function, blood sugar, blood fat all has no significant effect, internal organs naked eyes do not find that difference changes and histological examination result shows, medication 16 weeks and drug withdrawal are after 4 weeks, and Organs of Mice is all without obviously changing.Illustrate that toxicity is little after Chinese medicine additive of the present invention is to mouse long-term prescription, after drug withdrawal, also there is no difference reaction, application safety.
Contrast test
30 week age, body weight 400 of even, healthy laying hens are selected in experiment, be divided at random 4 groups, use respectively the feed (embodiment group 1-3) and the traditional egg feedstuff (control group) that contain embodiment of the present invention 1-3 additive to feed 90 days, collect each group of egg every day, choose at random 20 as sample for every group, measure egg size and cholesterol level of vitellus, assay method is high performance liquid chromatography, result is as shown in table 1, and the body weight of experiment fore-and-aft survey laying hen, calculates average daily gain.
Wherein, the feed that embodiment group 1 is used is the conventional feed that is added with feed addictive prepared by embodiment 1, and the content of feed addictive is 3% of feed gross weight; The feed that embodiment group 2 is used is the conventional feed that is added with feed addictive prepared by embodiment 2, and the content of feed addictive is 2% of feed gross weight; The feed that embodiment group 3 is used is the conventional feed that is added with Chinese medicine additive prepared by embodiment 3, and the content of feed addictive is 4% of feed gross weight; Control group is conventional feed.
Conventional feed forms by the raw material of following parts by weight: corn 401 weight portions, wheat 200 weight portions, corn protein powder 50 weight portions, maize alcohol lees 30 weight portions, dregs of beans 150 weight portions, peanut meal 45 weight portions, soya-bean oil 13.6 weight portions, stone flour 13.3 weight portions, calcium monohydrogen phosphate 16 weight portions and salt 3.1 weight portions.
Test is managed routinely and is carried out prerun at chicken house, compiles wing number, expelling parasite and immunization inocultation in preliminary trial period.Just before the examination phase, divided into groups (reducing error in group and between group), single cage is fed as far as possible.Free choice feeding, freely drinks water.Carry out routine work record and chicken health status record, experimental result is as shown in table 1.
The table of comparisons of table 1 egg egg size, cholesterol level of vitellus and laying rate
Note: normal data, colleague's shoulder motes same letter represents not remarkable (P > 0.05) of difference, the different alphabetical person of shoulder motes represents significant difference (P<0.05).
Data from table 1: the laying hen that uses the forage feed that contains embodiment of the present invention 1-3 additive, its egg size exceeds respectively egg 7.76g, the 8.60g and the 6.70g that use traditional egg feedstuff to feed laying hen, compared with the cholesterol level of vitellus of laying eggs that its cholesterol level of vitellus is fed laying hen with conventional feed, respectively low go out 4.53mg/g, 4.99mg/g and 4.11mg/g, the laying rate of laying hen that its laying rate is also fed apparently higher than conventional feed.
After experiment in above-mentioned 90 days finishes, every experimental group is chosen 10 laying hens and is tested for the second time, every group of test chicken carried out to artificial challenge, with 5 times of dilutions of culture of Escherichia coli for subsequent use, only, observed and recorded is respectively organized the incidence of disease and the death rate of laying hen, duration of test to lumbar injection 0.2mL/, continue to feed according to the mode of feeding of above-mentioned test, result of the test is as shown in table 2.
The table 2 challenge test result table of comparisons
Data from table 2: compared with conventional feed, the feed that uses the present invention to contain additive of the present invention can improve the resistance against diseases of laying hen, reduces the death rate.
Known by contrast experiment, the laying hen that the egg feedstuff that use contains embodiment of the present invention 1-3 additive is fed, its egg size, cholesterol level of vitellus and laying rate are all obviously better than the laying hen that uses conventional feed to feed, but also can improve the resistance against diseases of laying hen, use egg feedstuff of the present invention, not only can well meet the nutritional need of laying hen, but also can reduce the cholesterol level of yolk, improve laying rate and egg size.
The foregoing is only preferred embodiment of the present invention, in order to limit the present invention, within the spirit and principles in the present invention not all, any amendment of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (10)
1. a laying cycle of laying hens feed addictive, is characterized in that, described feed addictive comprises Chinese medicine additive, enzymatic compositions and neo dohyfral D3, and wherein, the ratio of weight and number of described Chinese medicine additive, enzymatic compositions and neo dohyfral D3 is 1:1:0.01-0.5; Described Chinese medicine additive comprises following raw medicinal material: marine alga, rhizoma atractylodis, Radix Codonopsis, caryophyllaceous ginseng, chrysanthemum, comfrey, pollen, Chinese scholartree leaf, the membrane of a chicken's gizzard, trifoliate orange, fructus amomi, Chinese yam, French beans, date, thizoma curculiginis, matrimony vine, walnut kernel, the seed of Chinese dodder, glutinous rice rhizome and root and maidenhair.
2. laying cycle of laying hens feed addictive according to claim 1, is characterized in that, described enzymatic compositions is one or more in zytase, 1,4 beta-glucanase, 'beta '-mannase, cellulase, amylase, phytase or protease.
3. laying cycle of laying hens feed addictive according to claim 1 and 2, it is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: marine alga 15-25 weight portion, rhizoma atractylodis 10-20 weight portion, Radix Codonopsis 15-25 weight portion, caryophyllaceous ginseng 10-15 weight portion, chrysanthemum 13-24 weight portion, comfrey 10-20 weight portion, pollen 10-20 weight portion, Chinese scholartree leaf 15-25 weight portion, the membrane of a chicken's gizzard 15-25 weight portion, trifoliate orange 10-18 weight portion, fructus amomi 10-16 weight portion, Chinese yam 10-20 weight portion, French beans 10-20 weight portion, date 10-20 weight portion, thizoma curculiginis 10-20 weight portion, matrimony vine 15-25 weight portion, walnut kernel 10-20 weight portion, seed of Chinese dodder 10-20 weight portion, glutinous rice rhizome and root 10-20 weight portion and maidenhair 10-15 weight portion.
4. according to the laying cycle of laying hens feed addictive described in claim 1-3 any one, it is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: marine alga 18 weight portions, rhizoma atractylodis 17 weight portions, Radix Codonopsis 19 weight portions, caryophyllaceous ginseng 13 weight portions, chrysanthemum 20 weight portions, comfrey 16 weight portions, pollen 15 weight portions, Chinese scholartree leaf 20 weight portions, the membrane of a chicken's gizzard 19 weight portions, trifoliate orange 14 weight portions, fructus amomi 13 weight portions, Chinese yam 15 weight portions, French beans 15 weight portions, date 17 weight portions, thizoma curculiginis 17 weight portions, matrimony vine 21 weight portions, walnut kernel 15 weight portions, the seed of Chinese dodder 15 weight portions, glutinous rice rhizome and root 15 weight portions and maidenhair 13 weight portions.
5. according to the laying cycle of laying hens feed addictive described in claim 1-4 any one, it is characterized in that, described Chinese medicine additive also comprises: glossy ganoderma, barley, lotus leaf, dried orange peel and paniculate swallowwort.
6. according to the laying cycle of laying hens feed addictive described in claim 1-5 any one, it is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: marine alga 15-25 weight portion, rhizoma atractylodis 10-20 weight portion, Radix Codonopsis 15-25 weight portion, caryophyllaceous ginseng 10-15 weight portion, chrysanthemum 13-24 weight portion, comfrey 10-20 weight portion, pollen 10-20 weight portion, Chinese scholartree leaf 15-25 weight portion, the membrane of a chicken's gizzard 15-25 weight portion, trifoliate orange 10-18 weight portion, fructus amomi 10-16 weight portion, Chinese yam 10-20 weight portion, French beans 10-20 weight portion, date 10-20 weight portion, thizoma curculiginis 10-20 weight portion, matrimony vine 15-25 weight portion, walnut kernel 10-20 weight portion, seed of Chinese dodder 10-20 weight portion, glutinous rice rhizome and root 10-20 weight portion, maidenhair 10-15 weight portion, glossy ganoderma 15-25 weight portion, barley 10-18 weight portion, lotus leaf 10-15 weight portion, dried orange peel 10-20 weight portion and paniculate swallowwort 10-15 weight portion.
7. according to the laying cycle of laying hens feed addictive described in claim 1-6 any one, it is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: marine alga 21 weight portions, rhizoma atractylodis 15 weight portions, Radix Codonopsis 20 weight portions, caryophyllaceous ginseng 12 weight portions, chrysanthemum 16 weight portions, comfrey 15 weight portions, pollen 15 weight portions, Chinese scholartree leaf 18 weight portions, the membrane of a chicken's gizzard 22 weight portions, trifoliate orange 14 weight portions, fructus amomi 13 weight portions, Chinese yam 15 weight portions, French beans 15 weight portions, date 15 weight portions, thizoma curculiginis 15 weight portions, matrimony vine 19 weight portions, walnut kernel 15 weight portions, the seed of Chinese dodder 15 weight portions, glutinous rice rhizome and root 15 weight portions, maidenhair 12 weight portions, glossy ganoderma 20 weight portions, barley 14 weight portions, lotus leaf 13 weight portions, dried orange peel 15 weight portions and paniculate swallowwort 13 weight portions.
8. according to the preparation method of laying cycle of laying hens feed addictive described in claim 1-7 any one, it is characterized in that, described preparation method comprises the following steps:
The first step, mixes above-mentioned various raw medicinal materials by ratio of weight and the number of copies, and input pulverizer is pulverized or directly chopping, pack into and decoct in container, add suitable quantity of water to make its submergence medicinal material, soak after 30-60 minute, be heated to seethe with excitement after 30-60 minute, separate fried liquid, the dregs of a decoction again add water and decoct 2-3 time, isolate respectively fried liquid at every turn, merge all fried liquid, after filtering, get filtrate and abandon filter residue again;
Second step, after filtrate is cooling, adding with respect to liquid weight 1-2 determining alcohol doubly after concentrated is 80-90% ethanol, fully mix, placement is spent the night, and makes its precipitation, after getting its supernatant liquid filtering next day, obtain filtrate, the ethanol that sediment is 50-60% with determining alcohol is cleaned, and collects washing lotion and merges with filtrate, decompression is regained after ethanol, leave standstill 0.5-1 hour, make precipitation completely, filter, filtrate low-temperature evaporation, obtains paste;
The 3rd step: paste is put into spray dryer dry, ensure that EAT is at 180 DEG C-200 DEG C, 70 DEG C-90 DEG C of leaving air temps, are ground into 200 order-300 orders subsequently, obtain Chinese medicine additive pulvis;
The 4th step: by weight Chinese medicine additive, enzymatic compositions and neo dohyfral D3 are mixed and obtain feed addictive.
9. a laying cycle of laying hens Chinese medicine additive, it is characterized in that, described Chinese medicine additive is made up of the raw medicinal material of following parts by weight: marine alga 15-25 weight portion, rhizoma atractylodis 10-20 weight portion, Radix Codonopsis 15-25 weight portion, caryophyllaceous ginseng 10-15 weight portion, chrysanthemum 13-24 weight portion, comfrey 10-20 weight portion, pollen 10-20 weight portion, Chinese scholartree leaf 15-25 weight portion, the membrane of a chicken's gizzard 15-25 weight portion, trifoliate orange 10-18 weight portion, fructus amomi 10-16 weight portion, Chinese yam 10-20 weight portion, French beans 10-20 weight portion, date 10-20 weight portion, thizoma curculiginis 10-20 weight portion, matrimony vine 15-25 weight portion, walnut kernel 10-20 weight portion, seed of Chinese dodder 10-20 weight portion, glutinous rice rhizome and root 10-20 weight portion, maidenhair 10-15 weight portion, glossy ganoderma 15-25 weight portion, barley 10-18 weight portion, lotus leaf 10-15 weight portion, dried orange peel 10-20 weight portion and paniculate swallowwort 10-15 weight portion.
10. the preparation method of laying cycle of laying hens feed addictive according to claim 9, is characterized in that, described preparation method comprises the following steps:
The first step, mixes various raw medicinal materials by ratio of weight and the number of copies, and input pulverizer is pulverized or directly chopping, pack into and decoct in container, add suitable quantity of water to make its submergence medicinal material, soak after 30-60 minute, be heated to seethe with excitement after 30-60 minute, separate fried liquid, the dregs of a decoction again add water and decoct 2-3 time, isolate respectively fried liquid at every turn, merge all fried liquid, after filtering, get filtrate and abandon filter residue again;
Second step, after filtrate is cooling, adding with respect to liquid weight 1-2 determining alcohol doubly after concentrated is 80-90% ethanol, fully mix, placement is spent the night, and makes its precipitation, after getting its supernatant liquid filtering next day, obtain filtrate, the ethanol that sediment is 50-60% with determining alcohol is cleaned, and collects washing lotion and merges with filtrate, decompression is regained after ethanol, leave standstill 0.5-1 hour, make precipitation completely, filter, filtrate low-temperature evaporation, obtains paste;
The 3rd step: paste is put into spray dryer dry, ensure that EAT is at 180 DEG C-200 DEG C, 70 DEG C-90 DEG C of leaving air temps, are ground into 200 order-300 orders subsequently, obtain Chinese medicine additive pulvis.
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| CN104351139A (en) * | 2014-12-01 | 2015-02-18 | 王德 | Method for enlarging egg yolk |
| CN105981958A (en) * | 2016-03-07 | 2016-10-05 | 倪皖生 | Layer feed capable of increasing laying rate of layers and preparation method thereof |
| CN106689779A (en) * | 2016-11-28 | 2017-05-24 | 徐州培源生物科技有限公司 | Production formula and production method of eggs for treating male prostatic disorders |
| CN108094696A (en) * | 2017-12-27 | 2018-06-01 | 福建光阳蛋业股份有限公司 | A kind of laying hen lotus leaf feed and preparation method thereof |
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Effective date of registration: 20160429 Address after: 224000 Jiangsu Province, Yancheng City Dongtai Economic Development Zone weft nine road No. 9 Patentee after: YANCHENG LIUHE FEED CO.,LTD. Address before: 266061 Shandong city of Qingdao province Chengyang Jihongtan Street Green Industrial Park Patentee before: SHANDONG NEW HOPE LIUHE GROUP Co.,Ltd. |
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