CN103874915B - 通过荧光法进行体外检测和/或定量的系统 - Google Patents
通过荧光法进行体外检测和/或定量的系统 Download PDFInfo
- Publication number
- CN103874915B CN103874915B CN201280046767.7A CN201280046767A CN103874915B CN 103874915 B CN103874915 B CN 103874915B CN 201280046767 A CN201280046767 A CN 201280046767A CN 103874915 B CN103874915 B CN 103874915B
- Authority
- CN
- China
- Prior art keywords
- signal
- digital
- carrier frequency
- frequency
- fluorescence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/06—Illumination; Optics
- G01N2201/062—LED's
- G01N2201/0624—Compensating variation in output of LED source
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1158532A FR2980577B1 (fr) | 2011-09-26 | 2011-09-26 | Systeme de detection et/ou de quantification in vitro par fluorimetrie |
| FR1158532 | 2011-09-26 | ||
| PCT/FR2012/052136 WO2013045807A1 (fr) | 2011-09-26 | 2012-09-25 | Systeme de detection et/ou de quantification in vitro par fluorimetrie |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103874915A CN103874915A (zh) | 2014-06-18 |
| CN103874915B true CN103874915B (zh) | 2018-08-10 |
Family
ID=47023007
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201280046767.7A Active CN103874915B (zh) | 2011-09-26 | 2012-09-25 | 通过荧光法进行体外检测和/或定量的系统 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9632031B2 (https=) |
| EP (1) | EP2776812A1 (https=) |
| JP (1) | JP6239515B2 (https=) |
| KR (1) | KR102099230B1 (https=) |
| CN (1) | CN103874915B (https=) |
| BR (1) | BR112014007122B1 (https=) |
| FR (1) | FR2980577B1 (https=) |
| IN (1) | IN2014DN03167A (https=) |
| WO (1) | WO2013045807A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104655863B (zh) * | 2015-02-10 | 2016-08-24 | 中国科学院苏州生物医学工程技术研究所 | 一种样品输送检测系统 |
| FR3035716B1 (fr) | 2015-04-30 | 2019-06-21 | Biomerieux | Machine et procede pour la detection automatisee in vitro d'analytes mettant en oeuvre une decomposition spectrale chromatique d'une reponse optique |
| IL300236B2 (en) * | 2017-01-30 | 2024-04-01 | Medibeacon Inc | Method for non-invasive monitoring of fluorescent tracer agent with diffuse reflection corrections |
| US10945324B2 (en) * | 2017-11-30 | 2021-03-09 | Osram Gmbh | External assessment device for a lighting system and method of assessing a lighting system |
| WO2020028766A1 (en) * | 2018-08-02 | 2020-02-06 | The Charles Stark Draper Laboratory, Inc. | Fluorescence lifetime well array reader and actuator |
| EP4012610A1 (en) * | 2020-12-11 | 2022-06-15 | Biomerieux | Detection method for sample presence and device associated |
| CN113720825B (zh) * | 2021-11-04 | 2022-02-08 | 四川丹诺迪科技有限公司 | 光学即时检测器及检测方法和应用 |
| CN114200541B (zh) * | 2021-12-02 | 2023-02-24 | 吉林大学 | 一种基于余弦点积梯度约束的三维重磁联合反演方法 |
| CN114705867A (zh) * | 2022-03-23 | 2022-07-05 | 浙江大学 | 基于调制解调技术的胎盘生长因子免疫荧光层析测定方法与装置 |
| CN115326762B (zh) * | 2022-07-08 | 2024-09-03 | 常州罗盘星检测科技有限公司 | 一种溶解氧浓度检测系统及检测方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5818582A (en) * | 1996-09-19 | 1998-10-06 | Ciencia, Inc. | Apparatus and method for phase fluorometry |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0241268A3 (en) | 1986-04-11 | 1989-02-08 | Sclavo Inc.West Coast | Improved pulse light system fluorometer |
| EP0574977B1 (en) * | 1987-11-05 | 1997-01-15 | BERG, James D | Direct method for detecting very low levels of coliform contamination |
| JPH029396A (ja) * | 1988-06-29 | 1990-01-12 | Hitachi Ltd | 蛍光測定法 |
| WO1990009637A1 (en) * | 1989-02-13 | 1990-08-23 | Research Corporation Technologies, Inc. | Method and means for parallel frequency acquisition in frequency domain fluorometry |
| US5032730A (en) * | 1989-10-02 | 1991-07-16 | Fuji Photo Film Co., Ltd. | Immunoassay apparatus |
| US5672515A (en) * | 1995-09-12 | 1997-09-30 | Optical Sensors Incorporated | Simultaneous dual excitation/single emission fluorescent sensing method for PH and pCO2 |
| US5639668A (en) | 1995-09-14 | 1997-06-17 | Boehringer Mannheim Corporation | Optical apparatus for performing an immunoassay |
| FI954511A0 (fi) | 1995-09-22 | 1995-09-22 | Labsystems Oy | Fluorometer |
| US5757013A (en) * | 1995-12-06 | 1998-05-26 | American Research Corporation Of Virginia | Fluorescence decay measurement by calculation of inner product |
| JPH10232592A (ja) * | 1997-02-18 | 1998-09-02 | Canon Inc | 画像記録装置及び画像再生装置 |
| US6157037A (en) * | 1998-12-04 | 2000-12-05 | Photosense, Llc | Sensing device and method for measuring emission time delay during irradiation of targeted samples |
| FR2848669B1 (fr) | 2002-12-12 | 2005-09-02 | Commissariat Energie Atomique | Procede de mesure d'une quantite de photons proportionnelle a la quantite de photons recus par l'objet et dispositif associe. |
| GB2404013B (en) * | 2003-07-17 | 2006-05-31 | Isis Innovation | Apparatus for and method of measuring fluorescence lifetime |
| US7653281B2 (en) * | 2004-09-02 | 2010-01-26 | Ramot At Tel-Aviv University Ltd. | Embedded channels, embedded waveguides and methods of manufacturing and using the same |
| US8149896B2 (en) * | 2006-01-04 | 2012-04-03 | Qualcomm, Incorporated | Spur suppression for a receiver in a wireless communication system |
| US8433384B2 (en) * | 2006-05-03 | 2013-04-30 | Covidien Lp | Method and apparatus for cerebral oximetry |
| US20070259451A1 (en) * | 2006-05-03 | 2007-11-08 | Heanue John F | Fluorescence measurement method and apparatus |
| BRPI0715823A2 (pt) * | 2006-08-24 | 2013-07-16 | Agency Science Tech & Res | sistema de detecÇço àtica compacto |
| CN101821609A (zh) * | 2007-08-29 | 2010-09-01 | 艾本德股份有限公司 | 用于多个样品的辐射度测量的设备和方法 |
| EA201000526A1 (ru) * | 2007-10-11 | 2010-12-30 | Басф Се | Спектрометр со светодиодной матрицей |
| US20110001963A1 (en) * | 2009-07-02 | 2011-01-06 | Durack Gary P | System and method for the measurement of multiple emissions from multiple parallel flow channels in a flow cytometry system |
| JP5747043B2 (ja) * | 2009-12-22 | 2015-07-08 | スリーエム イノベイティブ プロパティズ カンパニー | 微生物を検出する方法及びそのためのキット |
| JP5476206B2 (ja) * | 2010-02-02 | 2014-04-23 | 日本電子株式会社 | 蛍光顕微鏡装置 |
-
2011
- 2011-09-26 FR FR1158532A patent/FR2980577B1/fr active Active
-
2012
- 2012-09-25 CN CN201280046767.7A patent/CN103874915B/zh active Active
- 2012-09-25 BR BR112014007122-5A patent/BR112014007122B1/pt active IP Right Grant
- 2012-09-25 US US14/347,259 patent/US9632031B2/en active Active
- 2012-09-25 KR KR1020147011256A patent/KR102099230B1/ko active Active
- 2012-09-25 JP JP2014532449A patent/JP6239515B2/ja active Active
- 2012-09-25 IN IN3167DEN2014 patent/IN2014DN03167A/en unknown
- 2012-09-25 EP EP12773073.7A patent/EP2776812A1/fr not_active Withdrawn
- 2012-09-25 WO PCT/FR2012/052136 patent/WO2013045807A1/fr not_active Ceased
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5818582A (en) * | 1996-09-19 | 1998-10-06 | Ciencia, Inc. | Apparatus and method for phase fluorometry |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20140067152A (ko) | 2014-06-03 |
| BR112014007122B1 (pt) | 2020-11-17 |
| CN103874915A (zh) | 2014-06-18 |
| KR102099230B1 (ko) | 2020-04-10 |
| JP2014531019A (ja) | 2014-11-20 |
| WO2013045807A1 (fr) | 2013-04-04 |
| IN2014DN03167A (https=) | 2015-06-26 |
| US9632031B2 (en) | 2017-04-25 |
| JP6239515B2 (ja) | 2017-11-29 |
| FR2980577A1 (fr) | 2013-03-29 |
| EP2776812A1 (fr) | 2014-09-17 |
| US20140252246A1 (en) | 2014-09-11 |
| BR112014007122A2 (pt) | 2017-04-11 |
| FR2980577B1 (fr) | 2013-09-20 |
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| GR01 | Patent grant |