CN103798568A - 一种铁皮石斛龟苓膏及其制作方法 - Google Patents
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Abstract
本发明公开了一种铁皮石斛龟苓膏，它由以下成分组成：龟苓膏粉、甜味剂、稳定剂，余量为水。所述龟苓膏粉的原料组成及其重量份为：土茯苓5-10份、金银花10-20份、甘草5-10份、葛根3-8份、生地5-10份和铁皮石斛10-30份。上述中药材经淋洗、风干、粉碎制得龟苓膏粉，再将龟苓膏粉与甜味剂和稳定剂混合加水成糊状，制得初膏；初膏经高温灭菌、分装，冷却后得到龟苓膏成品。本发明所述龟苓膏不仅具有传统龟苓膏清热解毒、凉血活血、生津止渴的功效，由于铁皮石斛的加入，还兼具调节免疫、抗疲劳、补气养阴等功效。可以消除人们由繁忙的工作和学习所致的神疲乏力，有效地提高工作和学习效率。
Description
技术领域
本发明属于功能性食品研究领域，特别涉及一种含铁皮石斛的龟苓膏及其制备工艺。
背景技术
龟苓膏是历史悠久的传统药膳，相传最初是清宫中专供皇帝食用的名贵药物，传统龟苓膏含有土茯苓、金银花、甘草、葛根、生地等成分。土茯苓：性味甘淡，归肝、胃、脾经，具有解毒、除湿和利关节的功效。金银花：性甘寒，气芳香，干寒清热而不伤胃，芳香透达又可祛邪，既能宣散风热，还善清解血毒具有清热解毒、凉散风热的作用。甘草：味甘，归心、肺、脾、胃经，常与金银花同用，共奏清热解毒之效。葛根：性凉，味甘、辛。有解表退热，生津，透疹，升阳止泻之功效。生地：味甘，苦，微寒，归心、肝、肾经，具有滋阴清热，凉血补血的功效。
中国专利公开号CN10283566A，公开日2012年12月26日，公开了一种原味龟苓膏，它由以下原料制成：甘草、茯苓、金银花、蒲公英、槐花、巴西龟、栀子、白芷、罗汉果。所制得的龟苓膏具有清热去湿，旺血生肌，润肠通便的功效。不足之处是:所制得的龟苓膏在增强免疫、抗疲劳的功效方面作用甚微。
铁皮石斛在调节免疫、抗疲劳方面功效显著。近年来，我国不少医药学者和科研机构对铁皮石斛的药效进行研究，1985年，中山医科大学的研究表明：铁皮石斛具有增强T细胞、B细胞、NK细胞和巨噬细胞的作用，是一类前景可喜的中药免疫增强剂，可作为新的抗癌药物。1992年，福建中医学院研究发现，铁皮石斛有抗衰老功能，能大幅度提高动物体内SOD（延缓衰老的主要物质）水平，1992年，福建中医学院研究发现，李时珍所言的“轻身延年”得到了现代科技的验证。1993年，浙江医科大学进行药理测试证实，铁皮石斛有显著提高机体免疫功能，抗衰老，刺激唾液分泌、抗疲劳、耐缺氧等方面的作用。1996年，中科院华南植物研究所和中山医科大学肿瘤研究所通过动物实验，证实铁皮石斛多糖能显著提高外周白细胞数和促进淋巴细胞移动抑制因子，强有力地清除实验条件下免疫抑制剂环磷酰胺的加入所引发的副作用，因此它能提高机体免疫功能，是一种很有价值的中药类免疫增强剂。2000年，经浙江卫生防疫站检测表明有辅助抑制肿瘤的作用。
此外，铁皮石斛味甘、性微寒。《神农本草经》指出铁皮石斛具有生津、止渴、镇痛、消肿之功效。与配方中的土茯苓、金银花、甘草、葛根和生地配伍，可以增强其他成分的效果。药物之间协同作用使龟苓膏生津止渴、清热解毒的效果更明显。
由此可见，铁皮石斛的加入在赋予龟苓膏调节免疫、抗疲劳的作用之外，还能与配方中组分协同作用，增强药效。
发明内容
本发明所要解决的技术问题是：提供一种由铁皮石斛制成的龟苓膏及其制作方法，该龟苓膏具有调节免疫、抗疲劳的保健作用。
本发明所采取的技术方案是：一种铁皮石斛龟苓膏，其特征在于：由以下重量配比的成分组成：龟苓膏粉30-50%、甜味剂2-12%、稳定剂0.05-2.5%，余量为水；所述龟苓膏粉的原料组成及其重量份为：土茯苓5-10份、金银花10-20份、甘草5-10份、葛根3-8份、生地5-10份、和铁皮石斛10-30份。
优选的，所述甜味剂为蜂蜜或果葡糖浆的一种或者两种。
优选的，所述稳定剂为明胶、卡拉胶、海藻酸钠和羧甲基纤维素钠的混合物。
优选的，所述明胶、卡拉胶、海藻酸钠和羧甲基纤维素钠的重量比为：3~6:2~3:1~3:0.5~1.5。
所述的一种铁皮石斛龟苓膏的制作方法，包括以下步骤：
（1）称取所述土茯苓、金银花、葛根、人参、黄芪、熟地黄、灵芝和铁皮石斛，用水淋洗干净，阴干；
（2）将上述成分用超微粉碎机粉碎成过500-1000目筛的细粉；
（3）将甜味剂、稳定剂加入到上述细粉中，加热搅拌至糊化后，冷却成初膏；
（4）将上述初膏高温灭菌、分装，冷却后得到龟苓膏成品。
优选的，（2）中所述加热温度为85~95℃，并保温30~60s；（4）中所述高温灭菌方法为121℃保温30min，所述龟苓膏成品分装成100g/盒，冷却装置为冰箱。
本发明的有益效果是：本发明将铁皮石斛加到龟苓膏中，组方合理，既克服了铁皮石斛煎煮过程繁琐、味道苦涩、药效单一的不足，又赋予龟苓膏新的保健功能，符合中医基础和药食同补理论。制备方法简单易行、成本低，可操作性强，适合大众消费，极具推广价值。
具体实施方式
本发明不局限于以下所述的具体实施方式，以下所述仅为本发明的较佳实施例，并不用以限制本发明，凡在本发明的精神和原则之内所作的任何修改、等同替换和改进等，均应包含在本发明的保护范围之内。
现结合实施例对本发明技术方案进行进一步说明：
实施例1
配方：龟苓膏粉30kg、蜂蜜2kg、稳定剂0.05kg和水92.45kg。
龟苓膏粉的组成：土茯苓5份、金银花10份、甘草5份、葛根3份、生地5份、铁皮石斛10份。
稳定剂的组成：明胶3 份、卡拉胶2份、海藻酸钠1 份、羧甲基纤维素钠0.5 份。
制备方法：
将土茯苓、金银花、甘草、葛根、生地、铁皮石斛用水淋洗干净，阴干；用超微粉碎机粉碎成过500目筛的细粉；将甜味剂、稳定剂加入到上述细粉中，加热到85℃，保温60s，搅拌至糊化后，冷却成初膏；将上述初膏在121℃下灭菌30min，分装成100g/盒，置冰箱冷却后得到龟苓膏成品。
实施例2
配方：龟苓膏粉50kg、蜂蜜12kg、稳定剂2.5kg和水35.5kg。
龟苓膏粉的组成：土茯苓10份、金银花20份、甘草10份、葛根8份、生地10份、铁皮石斛20份。
稳定剂的组成：明胶6份、卡拉胶3份、海藻酸钠3份、羧甲基纤维素钠1.5 份。
制备方法：
将土茯苓、金银花、甘草、葛根、生地、铁皮石斛用水淋洗干净，阴干；用超微粉碎机粉碎成过1000目筛的细粉；将甜味剂、稳定剂加入到上述细粉中，加热到95℃，保温30s，搅拌至糊化后，冷却成初膏；将上述初膏在121℃下灭菌30min，分装成100g/盒，置冰箱冷却后得到龟苓膏成品。
实施例3
配方：龟苓膏粉40kg、蜂蜜4kg、果葡糖浆4kg、稳定剂2.5kg和水49.5kg。
龟苓膏粉的组成：土茯苓8份、金银花15份、甘草7份、葛根6份、生地9份、铁皮石斛16份。
稳定剂的组成：明胶4份、卡拉胶3份、海藻酸钠2份、羧甲基纤维素钠1 份。
制备方法：
将土茯苓、金银花、甘草、葛根、生地、铁皮石斛用水淋洗干净，阴干；用超微粉碎机粉碎成过800目筛的细粉；将甜味剂、稳定剂加入到上述细粉中，加热到90℃，保温50s，搅拌至糊化后，冷却成初膏；将上述初膏在121℃下灭菌30min，分装成100g/盒，置冰箱冷却后得到龟苓膏成品。
实施例4
配方：龟苓膏粉35kg、蜂蜜6kg、果葡糖浆2kg、稳定剂1kg和水56kg。
龟苓膏粉的组成：土茯苓6份、金银花18份、甘草6份、葛根8份、生地7份、铁皮石斛15份。
稳定剂的组成：明胶3份、卡拉胶2.5份、海藻酸钠2.5份、羧甲基纤维素钠1.2份。
制备方法：
将土茯苓、金银花、甘草、葛根、生地、铁皮石斛用水淋洗干净，阴干；用超微粉碎机粉碎成过800目筛的细粉；将甜味剂、稳定剂加入到上述细粉中，加热到905℃，保温45s，搅拌至糊化后，冷却成初膏；将上述初膏在121℃下灭菌30min，分装成100g/盒，置冰箱冷却后得到龟苓膏成品。
实施例5
铁皮石斛与配方中其他成分协同作用效果试验数据：
选取中医诊断“虚火烦燥，口舌生疮，津亏便秘”之症状者80例，随机分为两组，每组40例。A为试验组，每天食用实施例1所述的龟苓膏100g，连续食用60d；B为对照组，每天服用不含铁皮石斛的如实施例1所述的龟苓膏100g，连续食用60d。以上两组服用龟苓膏的时间和方法相同，每日饮食和生活方式基本相同，且试验期间不服用其他药物。相同的，实施例2-4也具有同样效果。
表1铁皮石斛与配方中其他成分协同作用效果试验结果
由以上数据可知，Z组效果明显优于B组。A组的治愈率为20%，而B组的治愈率只有2%。A组无效率3.75%，明显低于B组22.5%。由此可见A组所食用的龟苓膏清热解毒，生津通便作用更好，铁皮石斛的与其他成分之间的协同增效作用明显。
实施例6
含铁皮石斛的龟苓膏保健作用临床试验结果如下：
石某，男25岁，桂林市人，经常感冒，神疲乏力。经多方治疗一直未愈，每天食用实施例1所述铁皮石斛龟苓膏100g，2个月后症状明显改善。
李某，男40岁，南宁市人，患者诉：腰膝酸软，精神不振，懒言少语，工作效率低。后每天食用实施例2所述龟苓膏100g，1个月后精神面貌基本回复正常。
刘某，女12岁，百色市人，上课注意力不集中，没精打采，体质差易感冒。坚持每天食用实施例3所述铁皮石斛龟苓膏100g，3个月后上课能注意听讲，感冒次数明显减少，学习成绩显著提高。
许某，女45岁，玉林市人，易于疲乏或无明显原因感到精力不足，体力不支，工作生活都提不起精神和兴趣，每天食用实施例4所述铁皮石斛龟苓膏100g，
连续食用3个月后，自述精力充沛，疲乏感消失，工作效率提高，生活质量相应提高。
Claims (7)
1.一种铁皮石斛龟苓膏，其特征在于：由以下重量配比的成分组成：龟苓膏粉30-50%、甜味剂2-12%、稳定剂0.05-2.5%，余量为水；所述龟苓膏粉的原料组成及其重量份为：土茯苓5-10份、金银花10-20份、甘草5-10份、葛根3-8份、生地5-10份、和铁皮石斛10-30份。
2.根据权利要求1所述的铁皮石斛龟苓膏，其特征在于：所述甜味剂为蜂蜜或果葡糖浆的一种或者两种。
3.根据权利要求1或2所述的铁皮石斛龟苓膏，其特征在于：所述稳定剂为明胶、卡拉胶、海藻酸钠和羧甲基纤维素钠的混合物。
4.根据权利要求3所述的铁皮石斛龟苓膏，其特征在于：所述明胶、卡拉胶、海藻酸钠和羧甲基纤维素钠的重量比为：3~6:2~3:1~3:0.5~1.5。
5.一种权利要求1所述的龟苓膏的制备方法，其特征在于：包括以下步骤：
（1）称取所述土茯苓、金银花、葛根、人参、黄芪、熟地黄、灵芝和铁皮石斛，用水淋洗干净，阴干；
（2）将上述成分用超微粉碎机粉碎成过500-1000目筛的细粉；
（3）将甜味剂、稳定剂加入到上述细粉中，加热搅拌至糊化后，冷却成初膏；
（4）将上述初膏高温灭菌、分装，冷却后得到龟苓膏成品。
6.根据权利要求5所述的龟苓膏的制备方法，其特征在于：（2）中所述加热温度为85~95℃，并保温30~60s。
7.根据权利要求6所述的龟苓膏的制备方法，其特征在于：（4）中所述高温灭菌方法为121℃保温30min，所述龟苓膏成品分装成100g/盒，冷却装置为冰箱。
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| CN104719897A (zh) * | 2015-03-26 | 2015-06-24 | 宁波枫康生物科技有限公司 | 增强免疫力的复方铁皮石斛保健食品的配方及其制备方法 |
| CN104839522A (zh) * | 2015-04-17 | 2015-08-19 | 邹健 | 一种营养保健龟苓膏及其制备方法 |
| CN106036906A (zh) * | 2016-06-20 | 2016-10-26 | 广西梧州市港圣堂保健食品有限公司 | 一种养血安神富硒葛根龟苓膏及其制备方法 |
| CN113476572A (zh) * | 2021-07-27 | 2021-10-08 | 山东东阿东盛阿胶产品科技开发有限公司 | 一种石斛膏及其制备方法 |
| CN114304639A (zh) * | 2022-02-24 | 2022-04-12 | 河南城建学院 | 一种以亚麻籽胶为稳定剂的降血压龟苓膏及其制备方法 |
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