CN103739639A - 一种甜菊糖a苷晶体及其制备方法和用途 - Google Patents
一种甜菊糖a苷晶体及其制备方法和用途 Download PDFInfo
- Publication number
- CN103739639A CN103739639A CN201410044437.5A CN201410044437A CN103739639A CN 103739639 A CN103739639 A CN 103739639A CN 201410044437 A CN201410044437 A CN 201410044437A CN 103739639 A CN103739639 A CN 103739639A
- Authority
- CN
- China
- Prior art keywords
- stevioside
- crystal formation
- crystal
- glycosides
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
- C07H1/06—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (10)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410044437.5A CN103739639B (zh) | 2014-01-30 | 2014-01-30 | 一种甜菊糖a苷晶体及其制备方法和用途 |
PCT/CN2014/080908 WO2015113369A1 (zh) | 2014-01-30 | 2014-06-27 | 一种甜菊糖a苷晶体及其制备方法和用途 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410044437.5A CN103739639B (zh) | 2014-01-30 | 2014-01-30 | 一种甜菊糖a苷晶体及其制备方法和用途 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN103739639A true CN103739639A (zh) | 2014-04-23 |
CN103739639B CN103739639B (zh) | 2016-10-19 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201410044437.5A Active CN103739639B (zh) | 2014-01-30 | 2014-01-30 | 一种甜菊糖a苷晶体及其制备方法和用途 |
Country Status (2)
Country | Link |
---|---|
CN (1) | CN103739639B (zh) |
WO (1) | WO2015113369A1 (zh) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015113369A1 (zh) * | 2014-01-30 | 2015-08-06 | 诸城市浩天药业有限公司 | 一种甜菊糖a苷晶体及其制备方法和用途 |
WO2018166475A1 (zh) | 2017-03-16 | 2018-09-20 | 诸城市浩天药业有限公司 | 甜菊糖m苷晶型及制备方法和用途 |
CN112156183A (zh) * | 2020-08-21 | 2021-01-01 | 浙江皇冠科技有限公司 | 一种CpG复合佐剂及作为新型冠状病毒疫苗佐剂的用途 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101472487A (zh) * | 2006-06-19 | 2009-07-01 | 可口可乐公司 | 甜菊双糖苷a组合物及其纯化方法 |
WO2010118218A1 (en) * | 2009-04-09 | 2010-10-14 | Cargill, Incorporated | Sweetener composition comprising high solubility form of rebaudioside a and method of making |
CN102770436A (zh) * | 2009-12-31 | 2012-11-07 | 可口可乐公司 | 莱鲍迪苷a组合物和纯化莱鲍迪苷a的方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101812096A (zh) * | 2010-04-21 | 2010-08-25 | 赣州菊隆高科技实业有限公司 | 一种超声波结晶莱鲍迪甙a的方法 |
CN102766177A (zh) * | 2012-06-06 | 2012-11-07 | 天津北洋百川生物技术有限公司 | 结晶法提高甜菊糖中莱鲍迪甙a含量的方法 |
CN103739639B (zh) * | 2014-01-30 | 2016-10-19 | 诸城市浩天药业有限公司 | 一种甜菊糖a苷晶体及其制备方法和用途 |
-
2014
- 2014-01-30 CN CN201410044437.5A patent/CN103739639B/zh active Active
- 2014-06-27 WO PCT/CN2014/080908 patent/WO2015113369A1/zh active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101472487A (zh) * | 2006-06-19 | 2009-07-01 | 可口可乐公司 | 甜菊双糖苷a组合物及其纯化方法 |
WO2010118218A1 (en) * | 2009-04-09 | 2010-10-14 | Cargill, Incorporated | Sweetener composition comprising high solubility form of rebaudioside a and method of making |
CN102770436A (zh) * | 2009-12-31 | 2012-11-07 | 可口可乐公司 | 莱鲍迪苷a组合物和纯化莱鲍迪苷a的方法 |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015113369A1 (zh) * | 2014-01-30 | 2015-08-06 | 诸城市浩天药业有限公司 | 一种甜菊糖a苷晶体及其制备方法和用途 |
WO2018166475A1 (zh) | 2017-03-16 | 2018-09-20 | 诸城市浩天药业有限公司 | 甜菊糖m苷晶型及制备方法和用途 |
US11059843B2 (en) | 2017-03-16 | 2021-07-13 | Zhucheng Haotian Pharm Co., Ltd. | Stevioside M crystal form, preparation method therefor and use thereof |
CN112156183A (zh) * | 2020-08-21 | 2021-01-01 | 浙江皇冠科技有限公司 | 一种CpG复合佐剂及作为新型冠状病毒疫苗佐剂的用途 |
Also Published As
Publication number | Publication date |
---|---|
CN103739639B (zh) | 2016-10-19 |
WO2015113369A1 (zh) | 2015-08-06 |
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Legal Events
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: The invention relates to a stevioside a crystal and a preparation method and application thereof Effective date of registration: 20210918 Granted publication date: 20161019 Pledgee: Bank of Weifang Zhucheng sub branch Pledgor: ZHUCHENG HAOTIAN PHARM Co.,Ltd. Registration number: Y2021980009630 |
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PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20221122 Granted publication date: 20161019 Pledgee: Bank of Weifang Zhucheng sub branch Pledgor: ZHUCHENG HAOTIAN PHARM Co.,Ltd. Registration number: Y2021980009630 |
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PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A crystal of steviol glycoside A and its preparation method and application Effective date of registration: 20230829 Granted publication date: 20161019 Pledgee: Bank of Weifang Zhucheng sub branch Pledgor: ZHUCHENG HAOTIAN PHARM Co.,Ltd. Registration number: Y2023980054328 |