CN105037458A - 一种甜菊糖d苷晶型a、其制备方法及其应用 - Google Patents
一种甜菊糖d苷晶型a、其制备方法及其应用 Download PDFInfo
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
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- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
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- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
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Abstract
Description
2θ | d | 相对强度% |
4.53 | 19.5129 | 39.7 |
6.38 | 13.8374 | 46.4 |
10.37 | 8.5210 | 33.9 |
12.76 | 6.9319 | 54.9 |
13.52 | 6.5432 | 52.0 |
15.11 | 5.8596 | 27.8 |
16.45 | 5.3858 | 25.3 |
17.48 | 5.0695 | 100.0 |
17.96 | 4.9363 | 98.7 |
18.36 | 4.8291 | 21.0 |
18.64 | 4.7571 | 36.2 |
20.07 | 4.4197 | 73.7 |
20.49 | 4.3300 | 39.8 |
22.63 | 3.9259 | 57.0 |
24.18 | 3.6775 | 27.6 |
24.79 | 3.5891 | 23.8 |
26.19 | 3.4005 | 20.7 |
Claims (10)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510441922.0A CN105037458B (zh) | 2015-07-23 | 2015-07-23 | 一种甜菊糖d苷晶型a、其制备方法及其应用 |
PCT/CN2016/090898 WO2017012572A1 (zh) | 2015-07-23 | 2016-07-21 | 一种甜菊糖d苷晶型a、其制备方法及其应用 |
JP2018522843A JP2018526431A (ja) | 2015-07-23 | 2016-07-21 | レバウジオシドdの結晶形a、その製造方法およびその使用 |
EP16827263.1A EP3327025B1 (en) | 2015-07-23 | 2016-07-21 | Crystalline form a of rebaudioside d, and preparation method and application therefor |
US15/747,072 US10611789B2 (en) | 2015-07-23 | 2016-07-21 | Crystalline form A of rebaudioside D, and preparation method and application therefor |
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CN201510441922.0A CN105037458B (zh) | 2015-07-23 | 2015-07-23 | 一种甜菊糖d苷晶型a、其制备方法及其应用 |
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Publication Number | Publication Date |
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CN105037458A true CN105037458A (zh) | 2015-11-11 |
CN105037458B CN105037458B (zh) | 2018-12-28 |
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Country Status (5)
Country | Link |
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US (1) | US10611789B2 (zh) |
EP (1) | EP3327025B1 (zh) |
JP (1) | JP2018526431A (zh) |
CN (1) | CN105037458B (zh) |
WO (1) | WO2017012572A1 (zh) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105646616A (zh) * | 2016-03-24 | 2016-06-08 | 诸城市浩天药业有限公司 | 甜菊糖b苷晶型g、其制备方法、食品组合物及应用 |
WO2017012572A1 (zh) * | 2015-07-23 | 2017-01-26 | 诸城市浩天药业有限公司 | 一种甜菊糖d苷晶型a、其制备方法及其应用 |
WO2017120480A1 (en) | 2016-01-07 | 2017-07-13 | Purecircle Usa Inc. | Highly soluble steviol glycosides |
WO2018166475A1 (zh) | 2017-03-16 | 2018-09-20 | 诸城市浩天药业有限公司 | 甜菊糖m苷晶型及制备方法和用途 |
CN111788213A (zh) * | 2018-03-01 | 2020-10-16 | 三得利控股株式会社 | 高溶解性瑞鲍迪苷d |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11229229B2 (en) | 2016-06-14 | 2022-01-25 | Purecircle Usa Inc. | Steviol glycosides compositions, production methods and uses |
CN113226057A (zh) * | 2018-12-28 | 2021-08-06 | 三得利控股株式会社 | 组合物 |
EP4052772A4 (en) * | 2019-11-01 | 2023-10-18 | Suntory Holdings Limited | METHOD FOR PRODUCING CRYSTALLIZED PRODUCT CONTAINING REBAUDIOSIDE-D AND CRYSTALLIZED PRODUCT CONTAINING REBAUDIOSIDE-D |
Citations (6)
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WO2011112892A1 (en) * | 2010-03-12 | 2011-09-15 | Purecircle Usa Inc. | High-purity steviol glycosides |
CN102406113A (zh) * | 2011-09-30 | 2012-04-11 | 宁波绿之健药业有限公司 | Ra和rd复配甜菊糖的制备方法 |
WO2012082587A2 (en) * | 2010-12-13 | 2012-06-21 | Purecircle Usa | Highly soluble rebaudioside d |
CN102811627A (zh) * | 2010-01-28 | 2012-12-05 | 嘉吉公司 | 处理糖苷的混合物以获得更纯的形式的一种或多种这些糖苷的方法 |
EP2358730B1 (en) * | 2009-10-15 | 2014-01-15 | Purecircle SDN BHD | Method for preparing high-purity rebaudioside d |
CN103709215A (zh) * | 2013-12-31 | 2014-04-09 | 天津北洋百川生物技术有限公司 | 一种从甜菊糖结晶母液糖中提取莱鲍迪甙d的方法 |
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US8030481B2 (en) * | 2007-05-21 | 2011-10-04 | The Coca-Cola Company | Stevioside polymorphic and amorphous forms, methods for their formulation, and uses |
US20120230922A1 (en) | 2009-09-22 | 2012-09-13 | Redpoint Bio Corporation | Novel Polymorphs of Rebaudioside C and Methods for Making and Using the Same |
US8299224B2 (en) * | 2009-10-15 | 2012-10-30 | Purecircle Sdn Bhd | High-purity Rebaudioside D |
US8501261B2 (en) | 2010-05-21 | 2013-08-06 | Purecircle Sdn Bhd | High-purity Rebaudioside C and process for purification of the same |
WO2012082493A1 (en) * | 2010-12-13 | 2012-06-21 | Cargill, Incorporated | Crystalline forms of rebaudioside b |
CN102894325A (zh) | 2011-07-25 | 2013-01-30 | 成都华高瑞甜科技有限公司 | 复合甜味剂和制法、及改善甜菊糖苷类甜味剂口感的方法 |
CN104159908B (zh) | 2011-12-09 | 2016-05-04 | 苏州景泓生物技术有限公司 | 一种制备瑞鲍迪甙d和其他相关天然甜味剂新的工艺方法 |
US10905146B2 (en) * | 2013-07-12 | 2021-02-02 | The Coca-Cola Company | Compositions for improving rebaudioside M solubility |
CN105037458B (zh) * | 2015-07-23 | 2018-12-28 | 诸城市浩天药业有限公司 | 一种甜菊糖d苷晶型a、其制备方法及其应用 |
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2015
- 2015-07-23 CN CN201510441922.0A patent/CN105037458B/zh active Active
-
2016
- 2016-07-21 JP JP2018522843A patent/JP2018526431A/ja active Pending
- 2016-07-21 EP EP16827263.1A patent/EP3327025B1/en active Active
- 2016-07-21 WO PCT/CN2016/090898 patent/WO2017012572A1/zh active Application Filing
- 2016-07-21 US US15/747,072 patent/US10611789B2/en active Active
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EP2358730B1 (en) * | 2009-10-15 | 2014-01-15 | Purecircle SDN BHD | Method for preparing high-purity rebaudioside d |
CN102811627A (zh) * | 2010-01-28 | 2012-12-05 | 嘉吉公司 | 处理糖苷的混合物以获得更纯的形式的一种或多种这些糖苷的方法 |
WO2011112892A1 (en) * | 2010-03-12 | 2011-09-15 | Purecircle Usa Inc. | High-purity steviol glycosides |
WO2012082587A2 (en) * | 2010-12-13 | 2012-06-21 | Purecircle Usa | Highly soluble rebaudioside d |
CN102406113A (zh) * | 2011-09-30 | 2012-04-11 | 宁波绿之健药业有限公司 | Ra和rd复配甜菊糖的制备方法 |
CN103709215A (zh) * | 2013-12-31 | 2014-04-09 | 天津北洋百川生物技术有限公司 | 一种从甜菊糖结晶母液糖中提取莱鲍迪甙d的方法 |
Cited By (8)
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WO2017012572A1 (zh) * | 2015-07-23 | 2017-01-26 | 诸城市浩天药业有限公司 | 一种甜菊糖d苷晶型a、其制备方法及其应用 |
WO2017120480A1 (en) | 2016-01-07 | 2017-07-13 | Purecircle Usa Inc. | Highly soluble steviol glycosides |
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CN105646616A (zh) * | 2016-03-24 | 2016-06-08 | 诸城市浩天药业有限公司 | 甜菊糖b苷晶型g、其制备方法、食品组合物及应用 |
CN105646616B (zh) * | 2016-03-24 | 2019-08-06 | 诸城市浩天药业有限公司 | 甜菊糖b苷晶型g、其制备方法、食品组合物及应用 |
WO2018166475A1 (zh) | 2017-03-16 | 2018-09-20 | 诸城市浩天药业有限公司 | 甜菊糖m苷晶型及制备方法和用途 |
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CN111788213A (zh) * | 2018-03-01 | 2020-10-16 | 三得利控股株式会社 | 高溶解性瑞鲍迪苷d |
Also Published As
Publication number | Publication date |
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JP2018526431A (ja) | 2018-09-13 |
US10611789B2 (en) | 2020-04-07 |
EP3327025A4 (en) | 2019-02-27 |
EP3327025A1 (en) | 2018-05-30 |
EP3327025B1 (en) | 2021-03-24 |
US20180371002A1 (en) | 2018-12-27 |
WO2017012572A1 (zh) | 2017-01-26 |
CN105037458B (zh) | 2018-12-28 |
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Denomination of invention: Stevioside D crystal form a, preparation method and application thereof Effective date of registration: 20210918 Granted publication date: 20181228 Pledgee: Bank of Weifang Zhucheng sub branch Pledgor: ZHUCHENG HAOTIAN PHARM Co.,Ltd. Registration number: Y2021980009630 |
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Denomination of invention: A steviol D glycoside crystal form A, its preparation method and application Effective date of registration: 20230829 Granted publication date: 20181228 Pledgee: Bank of Weifang Zhucheng sub branch Pledgor: ZHUCHENG HAOTIAN PHARM Co.,Ltd. Registration number: Y2023980054328 |
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