CN103728461B - 移液管单元和吸移测试液体的方法 - Google Patents
移液管单元和吸移测试液体的方法 Download PDFInfo
- Publication number
- CN103728461B CN103728461B CN201310476030.5A CN201310476030A CN103728461B CN 103728461 B CN103728461 B CN 103728461B CN 201310476030 A CN201310476030 A CN 201310476030A CN 103728461 B CN103728461 B CN 103728461B
- Authority
- CN
- China
- Prior art keywords
- liquid
- volume
- test
- nozzle
- test liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L13/00—Cleaning or rinsing apparatus
- B01L13/02—Cleaning or rinsing apparatus for receptacle or instruments
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1004—Cleaning sample transfer devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1016—Control of the volume dispensed or introduced
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0615—Loss of fluid by dripping
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/141—Preventing contamination, tampering
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/143—Quality control, feedback systems
- B01L2200/146—Employing pressure sensors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1016—Control of the volume dispensed or introduced
- G01N2035/1018—Detecting inhomogeneities, e.g. foam, bubbles, clots
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12188267.4A EP2719461B8 (en) | 2012-10-12 | 2012-10-12 | Method of pipetting a test liquid |
| EP12188267.4 | 2012-10-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103728461A CN103728461A (zh) | 2014-04-16 |
| CN103728461B true CN103728461B (zh) | 2017-10-24 |
Family
ID=47022551
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310476030.5A Active CN103728461B (zh) | 2012-10-12 | 2013-10-12 | 移液管单元和吸移测试液体的方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9878322B2 (https=) |
| EP (1) | EP2719461B8 (https=) |
| JP (1) | JP6013303B2 (https=) |
| CN (1) | CN103728461B (https=) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103008037B (zh) * | 2012-12-31 | 2015-04-01 | 浙江大学 | 一种具有皮升级精度的自动化微液滴阵列筛选系统的使用方法 |
| JP6230450B2 (ja) * | 2014-03-10 | 2017-11-15 | 株式会社日立ハイテクノロジーズ | 分注装置及び分注方法 |
| JP2015175837A (ja) * | 2014-03-18 | 2015-10-05 | ソニー株式会社 | ピペットチップ用板状部材、ピペットチップ、液体撹拌用キット及び液体撹拌装置 |
| CN104049045A (zh) * | 2014-05-21 | 2014-09-17 | 江苏德峰药业有限公司 | 一种高粘度或高凝固点物质的气相针维护方法 |
| CN109406801A (zh) * | 2014-07-01 | 2019-03-01 | 深圳迈瑞生物医疗电子股份有限公司 | 样本分析仪及其样本采集和分配方法 |
| US10690690B2 (en) * | 2015-04-24 | 2020-06-23 | Hitachi High-Tech Corporation | Automatic analyser and method |
| ES2560110B1 (es) * | 2015-06-26 | 2016-09-09 | Grifols, S.A. | Aparato para la realización automática de análisis de inmunohematología en tarjetas de gel |
| EP3314269A4 (en) | 2015-06-26 | 2019-01-23 | Abbott Laboratories | REACTION TANK EXCHANGER DEVICE FOR DIAGNOSTIC ANALYZER |
| JP6676300B2 (ja) * | 2015-07-28 | 2020-04-08 | ヤマハ発動機株式会社 | 対象物移動方法及び装置 |
| DE102015011970B4 (de) * | 2015-09-09 | 2017-04-06 | Scienion Ag | Dispensiergerät und entsprechendes Dispensierverfahren |
| JP6823364B2 (ja) * | 2015-09-15 | 2021-02-03 | サッポロビール株式会社 | 樽洗浄方法及び樽洗浄装置 |
| EP3376235B1 (en) * | 2015-11-13 | 2020-02-26 | Konica Minolta, Inc. | Reaction method and surface plasmon-field enhanced fluorescence apparatus |
| CN105413773B (zh) * | 2015-12-22 | 2017-12-12 | 江苏四新界面剂科技有限公司 | 具有自动判别液体储罐内压功能的取液器 |
| WO2017223214A1 (en) | 2016-06-22 | 2017-12-28 | Abbott Laboratories | Liquid level sensing apparatus and related methods |
| US10503177B2 (en) * | 2016-08-03 | 2019-12-10 | Safe Harbor Associates LLC | Additive delivery system with sensors |
| JP2018096915A (ja) * | 2016-12-15 | 2018-06-21 | 株式会社堀場製作所 | 自動分析装置 |
| EP3594692B1 (en) * | 2017-03-08 | 2021-10-13 | Hitachi High-Tech Corporation | Automatic analysis device and automatic analysis method |
| EP3381560A1 (de) * | 2017-03-28 | 2018-10-03 | Eppendorf AG | Verfahren und dosiervorrichtung zum kontaktdosieren von flüssigkeiten |
| LU100170B1 (de) * | 2017-04-13 | 2018-10-15 | Cytena Gmbh | Verfahren zum Prozessieren einer flüssigen Probe |
| CN121499836A (zh) * | 2017-08-25 | 2026-02-10 | 拜克门寇尔特公司 | 用于生物样品分析仪器的物质分配系统 |
| WO2019060716A1 (en) * | 2017-09-25 | 2019-03-28 | Freenome Holdings, Inc. | SAMPLE EXTRACTION METHODS AND SYSTEMS |
| EP3477307B1 (en) * | 2017-10-24 | 2020-07-22 | F. Hoffmann-La Roche AG | Pipetting device and pipetting device positioning system |
| EP3502656B1 (en) * | 2017-12-22 | 2022-09-21 | Tecan Trading Ag | A pipetting apparatus, a liquid handling system and a method of controlling pipetting |
| JP7456719B2 (ja) | 2017-12-28 | 2024-03-27 | シスメックス株式会社 | 検体測定装置および検体測定方法 |
| JP7372245B2 (ja) * | 2017-12-28 | 2023-10-31 | フォーミュラトリクス・インターナショナル・ホールディング・リミテッド | 自動液体移送最適化分注を行う装置とその方法 |
| JP7376905B2 (ja) * | 2019-07-02 | 2023-11-09 | 株式会社ピーエムティー | 希釈装置 |
| CN110404597B (zh) * | 2019-08-08 | 2024-08-16 | 天津药明康德新药开发有限公司 | 一种多功能自清洁移液装置及其使用方法 |
| EP3832315B1 (en) * | 2019-12-06 | 2025-05-28 | F. Hoffmann-La Roche AG | Pipetting unit and pipetting method for closed liquid containers |
| JP7417463B2 (ja) * | 2020-04-24 | 2024-01-18 | 株式会社日立ハイテク | 分注装置、自動分析装置、分注方法 |
| CA3191169A1 (en) * | 2020-08-10 | 2022-02-17 | Agilent Technologies, Inc. | Pressure-based liquid level detection |
| US20220268796A1 (en) * | 2021-02-19 | 2022-08-25 | Roche Molecular Systems, Inc. | Method of Operating a Laboratory Instrument |
| GB2607892B (en) * | 2021-06-11 | 2026-03-18 | Spt Labtech Ltd | Liquid Dispensing Apparatus |
| US12226776B2 (en) | 2021-11-04 | 2025-02-18 | Instrumentation Laboratory Company | Preparing substances in a medical diagnostic system |
| EP4443167A4 (en) * | 2021-12-03 | 2025-11-12 | Horiba Ltd | BLOOD ANALYZER, BLOOD ANALYSIS PROCESS AND COMPUTER PROGRAM |
| EP4479549A4 (en) * | 2022-02-15 | 2026-03-04 | Gate Scient Inc | SAMPLE TESTING DEVICES AND PROCEDURES |
| CN115407077B (zh) * | 2022-05-19 | 2025-05-13 | 中元汇吉生物技术股份有限公司 | 样本加注设备、方法及分析仪 |
| CN115747050A (zh) * | 2022-11-18 | 2023-03-07 | 上海英医达医疗器械用品有限公司 | 减少气泡与残液的移液方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54155088A (en) * | 1978-05-29 | 1979-12-06 | Hitachi Ltd | Liquid sample partial injection method and its device |
| JPS57208461A (en) * | 1981-06-18 | 1982-12-21 | Shimadzu Corp | Distributing method for liquid sample |
| JPS62228954A (ja) * | 1986-03-31 | 1987-10-07 | Toshiba Corp | 自動化学分析装置の分注方法 |
| US5918291A (en) * | 1995-06-07 | 1999-06-29 | Inacu; Fulga | Method for liquid aspiration from a sealed container |
| US6370942B1 (en) * | 2000-05-15 | 2002-04-16 | Dade Behring Inc. | Method for verifying the integrity of a fluid transfer |
| JP4783170B2 (ja) * | 2006-02-13 | 2011-09-28 | 株式会社東芝 | 自動分析装置 |
| EP1947463A1 (en) * | 2007-01-16 | 2008-07-23 | Roche Diagnostics GmbH | Collection of liquid analytical samples for clinical analytical purpose |
| JP2008281480A (ja) * | 2007-05-11 | 2008-11-20 | Olympus Corp | ノズル洗浄方法およびノズル洗浄装置ならびに自動分析装置 |
| JP2010133924A (ja) * | 2008-10-28 | 2010-06-17 | Sysmex Corp | 液体吸引機構および試料分析装置 |
-
2012
- 2012-10-12 EP EP12188267.4A patent/EP2719461B8/en active Active
-
2013
- 2013-10-07 US US14/047,230 patent/US9878322B2/en active Active
- 2013-10-07 JP JP2013210414A patent/JP6013303B2/ja active Active
- 2013-10-12 CN CN201310476030.5A patent/CN103728461B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20140106467A1 (en) | 2014-04-17 |
| CN103728461A (zh) | 2014-04-16 |
| EP2719461C0 (en) | 2023-07-12 |
| EP2719461B1 (en) | 2023-07-12 |
| JP6013303B2 (ja) | 2016-10-25 |
| EP2719461B8 (en) | 2023-08-16 |
| EP2719461A1 (en) | 2014-04-16 |
| JP2014081371A (ja) | 2014-05-08 |
| US9878322B2 (en) | 2018-01-30 |
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Legal Events
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| C06 | Publication | ||
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| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |