CN103709252B - 识别癌细胞上表达的cd-43和cea的含糖表位的抗体及其使用方法 - Google Patents

识别癌细胞上表达的cd-43和cea的含糖表位的抗体及其使用方法 Download PDF

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CN103709252B
CN103709252B CN201310440188.7A CN201310440188A CN103709252B CN 103709252 B CN103709252 B CN 103709252B CN 201310440188 A CN201310440188 A CN 201310440188A CN 103709252 B CN103709252 B CN 103709252B
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antibody
seq
variable region
aminoacid sequence
cancer
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CN103709252A (zh
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R-H·林
L·林
S-Y·林
S-H·李
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Wholeheart Medical Biotechnology Co ltd
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Abgenomics Corp
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
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    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
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    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705

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CN201310440188.7A 2006-06-07 2007-06-07 识别癌细胞上表达的cd-43和cea的含糖表位的抗体及其使用方法 Expired - Fee Related CN103709252B (zh)

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US60/811850 2006-06-07
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