CN103664959A - 一种五元双环胍类化合物的制备方法 - Google Patents
一种五元双环胍类化合物的制备方法 Download PDFInfo
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- CN103664959A CN103664959A CN201310672456.8A CN201310672456A CN103664959A CN 103664959 A CN103664959 A CN 103664959A CN 201310672456 A CN201310672456 A CN 201310672456A CN 103664959 A CN103664959 A CN 103664959A
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- compound
- guanidine compounds
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- 0 CC(C)(C)OC(N*(C*=C)CN(C(c1c2cccc1)=O)C2=O)=O Chemical compound CC(C)(C)OC(N*(C*=C)CN(C(c1c2cccc1)=O)C2=O)=O 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
Abstract
Description
Claims (7)
Priority Applications (1)
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CN201310672456.8A CN103664959B (zh) | 2013-12-12 | 2013-12-12 | 一种五元双环胍类化合物的制备方法 |
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CN201310672456.8A CN103664959B (zh) | 2013-12-12 | 2013-12-12 | 一种五元双环胍类化合物的制备方法 |
Publications (2)
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CN103664959A true CN103664959A (zh) | 2014-03-26 |
CN103664959B CN103664959B (zh) | 2017-01-25 |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104592253A (zh) * | 2014-12-29 | 2015-05-06 | 惠州市莱佛士制药技术有限公司 | 一种替西罗莫司的新合成方法 |
CN106892845A (zh) * | 2017-02-28 | 2017-06-27 | 四川同晟生物医药有限公司 | 一种2,4‑二氨基丁酸衍生物及其制备方法 |
CN112159408A (zh) * | 2020-09-24 | 2021-01-01 | 天津市科莱博瑞科技有限公司 | 一种双环胍类化合物制备方法 |
CN114230490A (zh) * | 2021-12-28 | 2022-03-25 | 乐威医药(江苏)股份有限公司 | 一种n-烷基化双胺的制备方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102718768A (zh) * | 2012-06-26 | 2012-10-10 | 惠州市莱佛士制药技术有限公司 | 一种手性五元二环胍化合物及其制备方法和应用 |
CN103044434A (zh) * | 2012-12-17 | 2013-04-17 | 惠州市莱佛士制药技术有限公司 | 一种基于氮杂环丙烷的手性五元二环胍的制备方法 |
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2013
- 2013-12-12 CN CN201310672456.8A patent/CN103664959B/zh active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102718768A (zh) * | 2012-06-26 | 2012-10-10 | 惠州市莱佛士制药技术有限公司 | 一种手性五元二环胍化合物及其制备方法和应用 |
CN103044434A (zh) * | 2012-12-17 | 2013-04-17 | 惠州市莱佛士制药技术有限公司 | 一种基于氮杂环丙烷的手性五元二环胍的制备方法 |
Non-Patent Citations (1)
Title |
---|
付东: "ω-烯烃基胺及其它伯胺的合成", 《中国优秀硕士学位论文全文数据库工程科技Ⅰ辑》 * |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104592253A (zh) * | 2014-12-29 | 2015-05-06 | 惠州市莱佛士制药技术有限公司 | 一种替西罗莫司的新合成方法 |
CN104592253B (zh) * | 2014-12-29 | 2020-01-17 | 广东莱佛士制药技术有限公司 | 一种替西罗莫司的新合成方法 |
CN106892845A (zh) * | 2017-02-28 | 2017-06-27 | 四川同晟生物医药有限公司 | 一种2,4‑二氨基丁酸衍生物及其制备方法 |
CN112159408A (zh) * | 2020-09-24 | 2021-01-01 | 天津市科莱博瑞科技有限公司 | 一种双环胍类化合物制备方法 |
CN114230490A (zh) * | 2021-12-28 | 2022-03-25 | 乐威医药(江苏)股份有限公司 | 一种n-烷基化双胺的制备方法 |
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CN103664959B (zh) | 2017-01-25 |
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Address after: 516081 No. 5, science and technology innovation road, west science and Technology Park, Dayawan, Guangdong, Huizhou Applicant after: Raffles Guangdong Pharmaceutical Technology Co. Ltd. Address before: 516081 No. 5, science and technology innovation road, west science and Technology Park, Dayawan, Guangdong, Huizhou Applicant before: Raffles PharmaTech Co., Ltd. |
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TR01 | Transfer of patent right |
Effective date of registration: 20171225 Address after: Zi street Jinhui road Shenzhen city Guangdong province 518122 Pingshan District No. 14 pit Shenzhen Biological Medicine Innovation Industrial Park No. 1 Building 8 layer 801 Patentee after: SHENZHEN HUAXIAN PHARMACEUTICAL TECHNOLOGY CO., LTD. Address before: 516081 No. 5, science and technology innovation road, west science and Technology Park, Dayawan, Guangdong, Huizhou Patentee before: Raffles Guangdong Pharmaceutical Technology Co. Ltd. |
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PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A preparation method of five membered bicyclic guanidine compounds Effective date of registration: 20211201 Granted publication date: 20170125 Pledgee: Shenzhen hi tech investment small loan Co.,Ltd. Pledgor: SHENZHEN HWAGEN PHARMACEUTICAL CO.,LTD. Registration number: Y2021980013803 |