CN103656276A - Medicine for treating renal failure and preparation method of medicine - Google Patents

Medicine for treating renal failure and preparation method of medicine Download PDF

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CN103656276A
CN103656276A CN201310609736.4A CN201310609736A CN103656276A CN 103656276 A CN103656276 A CN 103656276A CN 201310609736 A CN201310609736 A CN 201310609736A CN 103656276 A CN103656276 A CN 103656276A
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medicine
fructus
herba
radix
renal failure
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CN103656276B (en
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刘明杰
孟琴
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WEIFANG INSTITUTE OF MODERN RHEUMATOLOGY
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WEIFANG INSTITUTE OF MODERN RHEUMATOLOGY
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Priority to CN201510191514.4A priority Critical patent/CN104758699A/en
Priority to CN201510191423.0A priority patent/CN104800626A/en
Priority to CN201310609736.4A priority patent/CN103656276B/en
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Priority to PCT/CN2014/092164 priority patent/WO2015078357A1/en
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Abstract

The invention relates to a traditional Chinese medicine and a preparation method thereof, in particular to a medicine for treating renal failure and the preparation method for the medicine. According to the medicine, bamboo flower, ossa draconis, angelica pubescens, tangerine peel, hedyotis diffusa, gynostemma pentaphyllum and climbing entada are used as main medicines, and henon bamboo, liquorice, dark plum, radix pseudostellariae, flos puerariae, lotus leaf, finger citron, motherwort, andrographis paniculata, jasmine, bamboo shavings, pawpaw and prepared rhizome of rehmannia are used as auxiliary medicines. From the principle that kidney is the source of acquired constitution and takes charge of water carriage in traditional Chinese medicine, the qi of the kidney is tonified, renal water is dredged, and the renal failure is treated on the basis of syndrome differentiation. The medicine has few side effects and high treatment efficacy, and can lighten the pain of a patient.

Description

Medicine for the treatment of renal failure and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine and preparation method thereof, especially a kind of medicine for the treatment of renal failure and preparation method thereof.
Background technology
Renal failure is nephrotic syndrome, can be caused by Different types of etiopathogenises, with glomerular basement membrane permeability, increases, and shows as one group of clinical syndrome that High-grade Proteinuria, hypoproteinemia, treating serious edema caused, hyperlipemia and other metabolism disorders are feature.
Nephrotic syndrome is divided into constitutional, Secondary cases and heritability three major types, and primary nephrotic syndrome belongs to primary glomerulopathy, and having multiple histological type to form is a kind of common clinical disease.Current treatment means is more single.Available medicine is also more single.And by a big chunk patient.After treatment, recurrence and probability are repeatedly very high.The misery causing to patient is very large.Existing Therapy of Nephrotic Syndrome means are single, and medicine toxic and side effects used is large, be now badly in need of that a kind of side effect is little, curative effect obviously and cost can alleviate the medicine of patient's slight illness relatively less.
Summary of the invention
The object of this invention is to provide that a kind of side effect is little, curative effect is high, can alleviate the medicine and preparation method thereof of the treatment renal failure of patient's slight illness.
The medicine for the treatment of renal failure of the present invention comprises the medicine of heavily treating as follows renal failure, it is characterized in that comprising the composition of following parts by weight: bamboo 15-55, Os Draconis 15-25, Radix Angelicae Pubescentis 15-25, Pericarpium Citri Reticulatae 15-25, Herba Hedyotidis Diffusae 15-45, Herb Gynostemmae Pentaphylli 15-25, climbing entada seed 15-35, Herba Lophatheri 5-15, Radix Glycyrrhizae 25-75, Fructus Mume 5-15, Radix Pseudostellariae 5-35, Flos puerariae lobatae 5-15, Folium Nelumbinis 5-15, Fructus Citri Sarcodactylis 5-15, Herba Leonuri 5-15, Herba Andrographis 5-15, Fructus Gardeniae 5-15, Caulis Bambusae In Taenia 15-55, Fructus Chaenomelis 5-15, Radix Rehmanniae Preparata 15-35.
As a further improvement on the present invention, the ratio of weight and number of above-mentioned each composition is as follows: bamboo 35-55, Os Draconis 15-25, Radix Angelicae Pubescentis 15-25, Pericarpium Citri Reticulatae 15-25, Herba Hedyotidis Diffusae 35-45, Herb Gynostemmae Pentaphylli 15-25, climbing entada seed 15-25, Herba Lophatheri 5-15, Radix Glycyrrhizae 55-75, Fructus Mume 5-15, Radix Pseudostellariae 5-15, Flos puerariae lobatae 5-15, Folium Nelumbinis 5-15, Fructus Citri Sarcodactylis 5-15, Herba Leonuri 5-15, Herba Andrographis 5-15, Fructus Gardeniae 5-15, Caulis Bambusae In Taenia 35-55, Fructus Chaenomelis 5-15, Radix Rehmanniae Preparata 30-35.
The preparation method of the medicine of above-mentioned treatment renal failure, comprises following steps in sequence:
A) bamboo, Radix Glycyrrhizae, Fructus Mume, Folium Nelumbinis, Fructus Citri Sarcodactylis, Radix Angelicae Pubescentis, Herba Leonuri, Herba Andrographis, Fructus Gardeniae, Caulis Bambusae In Taenia, Radix Rehmanniae Preparata are put into according to the above ratio in the warm water of 20-30 ℃ and soaked 4-6 hour, the parts by weight of warm water are 800-1200; Then drop into after marmite is heated to seethe with excitement and decoct 10-20 minute, then add Herba Lophatheri, Flos puerariae lobatae, Pericarpium Citri Reticulatae, turn little fire and keep fluidized state to continue to decoct 20-30 minute, filtering medicinal residues after natural cooling, obtain medicinal liquid No. one; Os Draconis, Radix Pseudostellariae, Fructus Chaenomelis, climbing entada seed are dropped into respectively in the warm water of warm water 100-200 weight portions and soak 4-6 hour, the temperature of warm water is 20-30 ℃, then Os Draconis, Radix Pseudostellariae, Fructus Chaenomelis, climbing entada seed and immersion liquid thereof are dropped into marmite together, being heated to water boiling continues to decoct 50 minutes, filtering medicinal residues, obtain medicinal liquid No. two after natural cooling.
B) by medicinal liquid of above gained, No. two medicinal liquid mix homogeneously, enter marmite and be heated to add Herba Hedyotidis Diffusae and Herb Gynostemmae Pentaphylli after boiling, keep fluidized state to continue to decoct 35 minutes, after natural cooling, obtain the medicine of described treatment renal failure.
Bamboo has another name called Concretio silicea Bambusae seu schizostachyi, Concretio silicea Bambusae seu schizostachyi, phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle etc. and belongs to mycota, Ascomycotina, gang pyrenomycetes, Hypocreales, Hypocreaceae, Concretio silicea Bambusae seu schizostachyi and belong to fungus.Be born in the bamboo grove that decays or be about to decay, medicinal part is the Stroma of Fungus Zhuhuang more.There is relieving cough and reducing sputum, regulating QI to relieve pain, relieving convulsion effect.
Os Draconis be ancient times mammal as if the fossil of the skeleton of class, rhinoceros class, Hippocampal cortex etc.Main function: tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing.
Radix Angelicae Pubescentis is the dry root of samphire Angelica pubescens, pungent, bitter, and tepor, for anemofrigid-damp arthralgia; Lumbocrural pain; Few cloudy volt wind headache, headache toothache.Modern study, Radix Angelicae Pubescentis has antiinflammatory, analgesia and sedation; Platelet aggregation is had to inhibitory action; And it is not have hypotensive effect, but lasting; Contained bergapten, xanthotoxin etc. have photosensitive and antitumor action.
Pericarpium Citri Reticulatae, another name: Pericarpium Citri tangerinae, expensive old, Folium Styracis Suberifoliae, Fructus Citri tangerinae skin, wide Pericarpium Citri tangerinae, Pericarpium Citri tangerinae, Citrus chachiensis Hort. C. Suavissima Tanaka, Pericarpium citri reticuatae chachiensis.Mature peel for rutaceae orange and variety thereof.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
Herba Hedyotidis Diffusae, formal name used at school: Hedyotis diffusa is the plant of Rubiaceae cerastium, the conventional treatment of traditional Chinese medical science dyspnea and cough due to lung-heat, laryngopharynx swelling and pain, acute appendicitis, furuncle and phyma skin infection, venom etc.
Herb Gynostemmae Pentaphylli is the herb of cucurbitaceous plant Herb Gynostemmae Pentaphylli.Claim again that paradise grass, Gospel are careless, superman's ginseng, Herb Gynostemmae Pentaphylli, Herba Gynostemmatis, Herba Gynostemmatis, Pentapanax and gynostemma pentaphyllum makino etc.Bitter in the mouth; Micro-sweet; Cool in nature.Cure mainly: body void is weak; Nephrasthenia emission; Leukopenia; Hyperlipemia; Viral hepatitis; Chronic gastroenteritis; Chronic tracheitis.
Climbing entada seed is the seed of tropical plants Caulis Bauhihiae Championii.Property flat, sweet in the mouth, puckery.Cure mainly: insomnia and dreamful sleep, children's's scaring, obstinate rheumatism etc.
Herba Lophatheri, is herbaceos perennial, high 40-90cm.Root stock tubbiness, hard.Another name is broken GUCAO, Gallus jabouillei rice grass, bamboo grass.Root is medicinal, the effect that has refrigerant, antipyretic, diuresis and hasten parturition.
Radix Glycyrrhizae, prescription name: Radix Glycyrrhizae, SHENGCAO, Radix Glycyrrhizae, Radix Glycyrrhizae Preparata, Radix Glycyrrhizae Preparata, the careless tip, Radix Glycyrrhizae uralensis, the SHENGCAO tip etc.For dicotyledon pulse family Leguminosae Radix Glycyrrhizae Glycyrrhiza uralensisFisch., Glycyrrhiza inflata Bat. G. inflataBat., or the root and rhizome of Glycyrrhiza glabra L. G. glabraL.Function cures mainly heat-clearing and toxic substances removing, expelling phlegm for arresting cough, gastral cavity abdomen etc.
Fructus Mume, calls dark plum, yellow son, closes Chinese prunus mume (sieb.) sieb.et zucc., does a branch prunus mume (sieb.) sieb.et zucc., for the almost ripe fruit of the prunus mume (sieb.) sieb.et zucc. Prunus mume of rosaceae plant deciduous tree, through pyrotechnics, smokes and forms.According to modern study, less containing sodium containing potassium is many in Fructus Mume, therefore, need long-term taking row potassium diuretic person should eat it; In Fructus Armeniacae Mume, containing multiple organic acid, be improved the effect of liver function, therefore hepatopath should eat it.
Radix Pseudostellariae, has another name called Radix Ginseng, virgin ginseng.Tuber for Caryophyllaceae herbaceos perennial pseudostellaria heterophylla.Sweet, micro-hardship, tepor.Qi-restoratives medicine, Qi-tonifying drug.Cure mainly: mend strengthening spleen and lung, supplementing QI for promoting the production of body fluid.
Flos puerariae lobatae is the dried floral of leguminous plant Pueraria lobota Puerarialobata (Willd.) Ohwi.There is the effect of heat clearing away, removing toxic substances, hepatoprotective, skin care, the kidney invigorating.
Folium Nelumbinis, prescription name: Folium Nelumbinis, Folium Nelumbinis, new lotus leaf, dry Folium Nelumbinis, burnt FOLIUM NELUMBINIS etc.It is the dried leaves of nymphaeaceae plant lotus.There is summer heat relieving and dampness eliminating, spleen invigorating yang invigorating, the effect of dissipating blood stasis hemostasis.
Fructus Citri Sarcodactylis, has another name called: nine pawl wood, the five fingers Fructus Citri tangerinae, Fructus Citri Sarcodactylis are the fruit of rutaceae Fructus Citri Sarcodactylis Citrus medica L. var. sarcodactylis Swingle.Pungent, bitter, sweet, warm, nontoxic; Enter liver, spleen, stomach three warps, have activating QI to eliminate phlegm, preventing or arresting vomiting relieving distension, the liver soothing and the spleen invigorating, the more kinds of medicinal functions of stomach function regulating.
Herba Leonuri is the herb of labiate Herba Leonuri.The root of Herba Leonuri, stem, flower, leaf, reality, and be all used as medicine, can be with using.Bitter, pungent, be slightly cold.Return liver, pericardium channel.Cure mainly: promoting blood flow to regulate menstruation, inducing diuresis to remove edema.
Herba Andrographis is acanthaceous plant Herba Andrographis (Andrographis paniculata(Burm.f.) Nees) herb or leaf.Have another name called Chun Lianqiuliu, Herba Andrographitis, Lan Helian, Radix Gentianae, golden Rhizoma et radix valerianae, Tremella aurantialba Bandoni et Zang hook, India's grass, Herba vallisneriae Spiralis etc.There are heat-clearing and toxic substances removing, antiinflammatory, reducing swelling and alleviating pain effect.
Fructus Gardeniae, another name Yellow Fructus Gardeniae, Fructus Gardeniae, white toad, be the fruit of Maguireothamnus speciosus Fructus Gardeniae.At present, the fruit of Fructus Gardeniae is Chinese medicine, and the l that belongs to Ministry of Public Health promulgation criticizes medicine-food two-purpose resource, has the effects such as hepatoprotective, function of gallbladder promoting, blood pressure lowering, calmness, hemostasis, detumescence.At tcm clinical practice, be usually used in treating the diseases such as icterohepatitis, bruise, hypertension, diabetes.
Caulis Bambusae In Taenia, has another name called bamboo skin, and QINGZHU is eaten, and phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle skin is eaten.It is the dry intermediate layer of the stem stalk of grass bambusa breviflora Munro, major part allusion quotation bamboo or phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle.Containing lignin, cellulose.Cold nature, sweet in the mouth.The traditional Chinese medical science is usually used in for cough due to lung-heat, and expectorant Huang and febrile disease are irritated, palpitation with fear.
Fructus Chaenomelis is rosaceous plant chaenomeles lagenaria (Chaenomeles speciosa(Sweet) Nakai .) dry almost ripe fruit.Nature and flavor: acid, temperature.Return liver, spleen channel.Cure mainly: suppressing the hyperactive liver relaxing muscles and tendons, stomach function regulating removing dampness.For arthralgia chiefly caused by damp pathogen contracture, the heavy pain of waist knee joint acid, the convulsion of vomiting and diarrhoea, beriberi edema.
Radix Rehmanniae Preparata, for scrophulariaceae rehmannia glutinosa plant (formal name used at school: tuber Rehmannia glutinosa), have another name called Radix Rehmanniae Preparata or throw oneself on the ground, through processing, concoct and to form.There is the YIN nourishing of enriching blood effect, can be used for blood deficiency and yellow complexion, dizzy, palpitation and insomnia, menoxenia, the diseases such as metrorrhagia, also can be used for hectic fever hectic fever due to YIN-deficiency, the night sweat of deficiency of kidney yin, the disease such as pass out semen, quench one's thirst.
The medicine for the treatment of renal failure of the present invention, take bamboo, Os Draconis, Radix Angelicae Pubescentis, Pericarpium Citri Reticulatae, Herba Hedyotidis Diffusae, Herb Gynostemmae Pentaphylli, climbing entada seed is principal agent thing, phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle, Radix Glycyrrhizae, Fructus Mume, Radix Pseudostellariae, Flos puerariae lobatae, Folium Nelumbinis, Fructus Citri Sarcodactylis, Herba Leonuri, Herba Andrographis, Fructus Gardeniae, Caulis Bambusae In Taenia, Fructus Chaenomelis, Radix Rehmanniae Preparata are accessory drugs, it from Kidney Theory in TCM, is the principle of the foundation of acquired constitution, the main water transport of kidney, support the gas of kidney, row kidney water, Coryza Treated by Syndrome Differentiation renal failure, side effect is little, curative effect is high, can alleviate patient's slight illness.
The specific embodiment
Embodiment 1:
Standby medicine, the composition preparation method of preparing following parts by weight is as follows: bamboo 15-55, Os Draconis 15-25, Radix Angelicae Pubescentis 15-25, Pericarpium Citri Reticulatae 15-25, Herba Hedyotidis Diffusae 15-45, Herb Gynostemmae Pentaphylli 15-25, climbing entada seed 15-35, Herba Lophatheri 5-15, Radix Glycyrrhizae 25-75, Fructus Mume 5-15, Radix Pseudostellariae 5-35, Flos puerariae lobatae 5-15, Folium Nelumbinis 5-15, Fructus Citri Sarcodactylis 5-15, Herba Leonuri 5-15, Herba Andrographis 5-15, Fructus Gardeniae 5-15, Caulis Bambusae In Taenia 15-55, Fructus Chaenomelis 5-15, Radix Rehmanniae Preparata 15-35.Above-mentioned concrete component content can be adjusted according to the feature and the raw-material source that adapt to disease in above-mentioned scope.
A) bamboo, Radix Glycyrrhizae, Fructus Mume, Folium Nelumbinis, Fructus Citri Sarcodactylis, Radix Angelicae Pubescentis, Herba Leonuri, Herba Andrographis, Fructus Gardeniae, Caulis Bambusae In Taenia, Radix Rehmanniae Preparata are put into according to the above ratio in the warm water of 20-30 ℃ and soaked 4-6 hour, the parts by weight of warm water are 800-1200; Then drop into after marmite is heated to seethe with excitement and decoct 10-20 minute, then add Herba Lophatheri, Flos puerariae lobatae, Pericarpium Citri Reticulatae, turn little fire and keep fluidized state to continue to decoct 20-30 minute, filtering medicinal residues after natural cooling, obtain medicinal liquid No. one; Os Draconis, Radix Pseudostellariae, Fructus Chaenomelis, climbing entada seed are dropped into respectively in the warm water of warm water 100-200 weight portions and soak 4-6 hour, the temperature of warm water is 20-30 ℃, then Os Draconis, Radix Pseudostellariae, Fructus Chaenomelis, climbing entada seed and immersion liquid thereof are dropped into marmite together, being heated to water boiling continues to decoct 50 minutes, filtering medicinal residues, obtain medicinal liquid No. two after natural cooling.
B) by medicinal liquid of above gained, No. two medicinal liquid mix homogeneously, enter marmite and be heated to add Herba Hedyotidis Diffusae and Herb Gynostemmae Pentaphylli after boiling, keep fluidized state to continue to decoct 35 minutes, after natural cooling, obtain the medicine of described treatment renal failure.
Instructions of taking is as follows: it is a that the medicine of above-mentioned treatment renal failure is divided into every 50 grams, take for three times every day, and oral each portion, every 15 days is a course for the treatment of.
Patient Mrs Wang, 31 years old.Whole individual spirit is tired standby, with a haggard face, emaciated physique, and health is very poor.Result of laboratory test report shows: serum creatinine 716 μ mol/L, urine protein ++, blood uric acid 502.7 umol/L, blood urea nitrogen 28.2mmol/L.B ultrasonic shows: two kidneys atrophy of patient, left kidney 7.5CM, right kidney 7.9CM.Comprehensive indices diagnostic result is: uremia's middle and advanced stage, two renal atrophys, hyperuricemia.According to kidneys of patients Index for examination, the patient renal extent of damage is judged, after adopting the Drug therapy one month of the present embodiment, its spirit foot, complexion might as well, walked all energetically, appetite increases, and sleeps also normal, and blood test creatinine has dropped to 324 umol/L, blood uric acid drops to 436 micromoles, and blood urea nitrogen drops to 18.5.After second month, 85umol/L has fallen again in creatinine, and 5mmol/L has fallen in blood urea nitrogen.CO2 combining power, CO2 CP and blood uric acid have all reached normal index, and after the 3rd month, majority parameters trend is in normally.Present stable disease.Physical condition is clearly better, and can do farm work.
Embodiment 2:
For medicine, prepare the composition of following parts by weight: bamboo 35-55, Os Draconis 15-25, Radix Angelicae Pubescentis 15-25, Pericarpium Citri Reticulatae 15-25, Herba Hedyotidis Diffusae 35-45, Herb Gynostemmae Pentaphylli 15-25, climbing entada seed 15-25, Herba Lophatheri 5-15, Radix Glycyrrhizae 55-75, Fructus Mume 5-15, Radix Pseudostellariae 5-15, Flos puerariae lobatae 5-15, Folium Nelumbinis 5-15, Fructus Citri Sarcodactylis 5-15, Herba Leonuri 5-15, Herba Andrographis 5-15, Fructus Gardeniae 5-15, Caulis Bambusae In Taenia 35-55, Fructus Chaenomelis 5-15, Radix Rehmanniae Preparata 30-35.Above-mentioned concrete component content can be adjusted according to the feature and the raw-material source that adapt to disease in above-mentioned scope.
Preparation method and instructions of taking are with embodiment 1.
Patient marquis so-and-so, man, 34 years old.Over 5 years there is the urinary tract infection symptoms such as frequent micturition dysurea urgent micturition and chronic problem without obvious inducement and increase with heating, aversion to cold, dizzy weak, nocturia in patient repeatedly.Mental weariness during admission examination, inappetence, nauseating, vomiting, patient is middle upper abdomen or full abdomen pain sometimes, and Zuo Shen district and costispinal angle knocking are positive.Laboratory and auxiliary examination: leucocytosis, albuminuria +++, urine is occulted blood ++, the super pair inequality in size of kidneys that check of two kidney b.Adopt the auxiliary acupuncture and moxibustion therapy of Drug therapy of the present embodiment.After 6 days, patient's renal blood perfusion starts to increase, and glomerular filtration rate improves gradually, and urine creatine excretion increases gradually, and serum creatinine starts to decline gradually.Treat after 10 days, leave hospital.Follow the tracks of and pay a return visit two months, conditions of patients does not occur repeatedly, in good condition.Advise check after six months.
Embodiment 3:
For medicine, prepare the composition of following parts by weight: bamboo 35, Os Draconis 15, Radix Angelicae Pubescentis 15, Pericarpium Citri Reticulatae 15, Herba Hedyotidis Diffusae 35, Herb Gynostemmae Pentaphylli 15, climbing entada seed 25, Herba Lophatheri 5, Radix Glycyrrhizae 55, Fructus Mume 5, Radix Pseudostellariae 15, Flos puerariae lobatae 15, Folium Nelumbinis 5, Fructus Citri Sarcodactylis 5, Herba Leonuri 5, Herba Andrographis 5, Fructus Gardeniae 5, Caulis Bambusae In Taenia 35, Fructus Chaenomelis 5, Radix Rehmanniae Preparata 30.
Preparation method and instructions of taking are with embodiment 1.
Patient is in so-and-so, man, people from Shanxi.One year over panesthesia to feeling sick, weak, felt be at that time operating pressure excessive due to, be not present to the mind yet.But, after one month, just there is dizziness, headache, anorexia, a series of symptom such as uncomfortable in chest.To hospital, check, the Drug therapy of serum creatinine 490umol/L, blood pressure 230/170mmHg, employing embodiment 2, through the treatment of first stage one and a half months.Patient's spirit muscle power is recovered gradually, and renal function obviously recovers, and checks that serum creatinine controls to 400umol/L.Appetite is recovered.The result of again holding a consultation.Determine to adopt the Drug therapy of the present embodiment, mend strengthening spleen and lung, supplementing QI for promoting the production of body fluid, increase the antiviral ability of patient, supplement strong its muscles and bones of kidney qi, through second stage after 2 courses for the treatment of renal function recover gradually, check serum creatinine 200umol/L left and right.Rear patient leaves hospital voluntarily, suggestion continue to take two the course for the treatment of medicine, after six months check.
Through clinic trial statistics, choose person having renal failure 50 people that a variety of causes causes, cure 32 people, 15 people that have clear improvement, invalid 2 people, 1 people that transfers from one hospital to another, comprehensive cure rate is 64%, effective percentage is 94%.

Claims (3)

1. treat the medicine of renal failure, it is characterized in that comprising the composition of following parts by weight: bamboo 15-55, Os Draconis 15-25, Radix Angelicae Pubescentis 15-25, Pericarpium Citri Reticulatae 15-25, Herba Hedyotidis Diffusae 15-45, Herb Gynostemmae Pentaphylli 15-25, climbing entada seed 15-35, Herba Lophatheri 5-15, Radix Glycyrrhizae 25-75, Fructus Mume 5-15, Radix Pseudostellariae 5-35, Flos puerariae lobatae 5-15, Folium Nelumbinis 5-15, Fructus Citri Sarcodactylis 5-15, Herba Leonuri 5-15, Herba Andrographis 5-15, Fructus Gardeniae 5-15, Caulis Bambusae In Taenia 15-55, Fructus Chaenomelis 5-15, Radix Rehmanniae Preparata 15-35.
2. the medicine for the treatment of renal failure according to claim 1, is characterized in that the parts by weight of each composition are as follows: bamboo 35-55, Os Draconis 15-25, Radix Angelicae Pubescentis 15-25, Pericarpium Citri Reticulatae 15-25, Herba Hedyotidis Diffusae 35-45, Herb Gynostemmae Pentaphylli 15-25, climbing entada seed 15-25, Herba Lophatheri 5-15, Radix Glycyrrhizae 55-75, Fructus Mume 5-15, Radix Pseudostellariae 5-15, Flos puerariae lobatae 5-15, Folium Nelumbinis 5-15, Fructus Citri Sarcodactylis 5-15, Herba Leonuri 5-15, Herba Andrographis 5-15, Fructus Gardeniae 5-15, Caulis Bambusae In Taenia 35-55, Fructus Chaenomelis 5-15, Radix Rehmanniae Preparata 30-35.
3. the preparation method of the medicine for the treatment of renal failure according to claim 1 and 2, is characterized in that comprising following steps in sequence:
A) bamboo, Radix Glycyrrhizae, Fructus Mume, Folium Nelumbinis, Fructus Citri Sarcodactylis, Radix Angelicae Pubescentis, Herba Leonuri, Herba Andrographis, Fructus Gardeniae, Caulis Bambusae In Taenia, Radix Rehmanniae Preparata are put into according to the above ratio in the warm water of 20-30 ℃ and soaked 4-6 hour, the parts by weight of warm water are 800-1200; Then drop into after marmite is heated to seethe with excitement and decoct 10-20 minute, then add Herba Lophatheri, Flos puerariae lobatae, Pericarpium Citri Reticulatae, turn little fire and keep fluidized state to continue to decoct 20-30 minute, filtering medicinal residues after natural cooling, obtain medicinal liquid No. one; Os Draconis, Radix Pseudostellariae, Fructus Chaenomelis, climbing entada seed are dropped into respectively in the warm water of warm water 100-200 weight portions and soak 4-6 hour, the temperature of warm water is 20-30 ℃, then Os Draconis, Radix Pseudostellariae, Fructus Chaenomelis, climbing entada seed and immersion liquid thereof are dropped into marmite together, being heated to water boiling continues to decoct 50 minutes, filtering medicinal residues, obtain medicinal liquid No. two after natural cooling;
B) by medicinal liquid of above gained, No. two medicinal liquid mix homogeneously, enter marmite and be heated to add Herba Hedyotidis Diffusae and Herb Gynostemmae Pentaphylli after boiling, keep fluidized state to continue to decoct 35 minutes, after natural cooling, obtain the medicine of described treatment renal failure.
CN201310609736.4A 2013-11-27 2013-11-27 Medicine for the treatment of renal failure and preparation method thereof Expired - Fee Related CN103656276B (en)

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