CN101130056A - Traditional Chinese medicine used for treating chronic decline of kidney - Google Patents
Traditional Chinese medicine used for treating chronic decline of kidney Download PDFInfo
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- CN101130056A CN101130056A CNA2006100303245A CN200610030324A CN101130056A CN 101130056 A CN101130056 A CN 101130056A CN A2006100303245 A CNA2006100303245 A CN A2006100303245A CN 200610030324 A CN200610030324 A CN 200610030324A CN 101130056 A CN101130056 A CN 101130056A
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Abstract
The invention discloses a Chinese medicament for treating chronic kidney failure, wherein the constituents include (by weight percent) prepared rehmannia root 20-24%, astragalus root 38-50% and motherwort 30-38%.
Description
Technical field:
The present invention relates to a kind of Chinese medicine that is used for the treatment of chronic kidney hypofunction, particularly a kind of is the pure Chinese medicine composition of the treated chronic kidney hypofunction made of raw material with the vegetable Chinese herbal medicine.
Background technology:
(be called for short: formation reason CRF) is a lot, and as hypertension, electrolyte imbalance, glucose metabolism confusion, protein metabolism confusion etc., CRF forms the back along with the direction progress of shifting to whole latter stage of CRF (uremia) after the time for chronic kidney hypofunction.Dialysis and renal transplantation are still the only selection of present treatment CRF uremic patient, and badness come-off also may take place at any time.Global at present clinical report of also not curing CRF, the curative effect of other relevant report is nonspecific, it is alleviation to symptom, the elaboration that the glomerule unit of also the CRF phase not being damaged in the pertinent literature in the whole world and the report has the mechanism of repairing effect is with the elaboration of relevant this respect curative effect.
Documents 1, publication number: CN1745777, number of patent application: 200410074322.7, patentee: Ju Jianwei, " a kind of Chinese medicinal herbs decoction for the treatment of chronic kidney hypofunction " disclosed in this case, its technical scheme is that medicine is formed: Radix Et Rhizoma Rhei 30 grams, Os Draconis (calcined) 60 grams, Concha Ostreae (calcined) 60 grams, Herba Taraxaci 60 grams, Algin 3 grams.Make the medicinal liquid of 500ml according to this ratio through decocting in water, filtration, sterilization, it is standby to be divided into two 250ml/ bags.
Documents 2, publication number: CN1544029, number of patent application: 200310110934.2, patentee: Yuan Fahuan, disclose " a kind of medicine for the treatment of chronic kidney hypofunction and preparation method thereof " in this case, its technical scheme is, be the raw material prescription with Rhizoma Chuanxiong, the Radix Astragali, Radix Et Rhizoma Rhei, Radix Angelicae Sinensis, Herba Epimedii, the Radix Rehmanniae, the Radix Paeoniae Alba, Rhizoma Alismatis, Poria, Radix Notoginseng after, after pretreatment such as pulverizing, solvent extraction, again through ripening, sterilization, granulate finished product.
Summary of the invention:
The object of the present invention is to provide a kind of Chinese medicine that is used for the treatment of chronic kidney hypofunction, it has the CRF of falling phase blood pressure, improves glucose metabolism, equilibrium electrolyte, improves the CRF microcirculation, has overcome the deficiency on the prior art.
To achieve these goals, technical scheme of the present invention is: a kind of Chinese medicine that is used for the treatment of chronic kidney hypofunction, it is characterized in that: described Chinese medicine is made up of Radix Rehmanniae Preparata, the Radix Astragali, Herba Leonuri, and its percentage by weight is: Radix Rehmanniae Preparata 20%-24%, Radix Astragali 38%-50%, Herba Leonuri 30%-38%.
The invention discloses a kind of Chinese medicine that is used for the treatment of chronic kidney hypofunction, it is to gain knowledge according to modern Chinese medicine, to the pathogenetic understanding of chronic kidney hypofunction, from motherland's medical treasure-house, filter out the Chinese crude drug that has no side effect, according to the theoretical prescription of modern Chinese medicine, develop the Chinese medicine composition that to treat chronic kidney hypofunction, it can effectively reduce CRF phase blood pressure, improve glucose metabolism, equilibrium electrolyte, improve the CRF microcirculation and the effect of repairing the glomerule that the CRF phase damages is arranged, the effect of curing early stage chronic kidney hypofunction is arranged, uremic patient is had the effect of mitigate the disease.
The invention discloses a kind of Chinese medicine that is used for the treatment of chronic kidney hypofunction, it is different from prior art and is: described Chinese medicine is made up of Radix Rehmanniae Preparata, the Radix Astragali, Herba Leonuri, and its percentage by weight is: Radix Rehmanniae Preparata 20%-24%, Radix Astragali 38%-50%, Herba Leonuri 30%-38%.
In first embodiment of the invention, its mass percent can be: Radix Rehmanniae Preparata 20%, the Radix Astragali 42%, Herba Leonuri 38%.
In second embodiment of the invention, its mass percent can be: Radix Rehmanniae Preparata 22%, the Radix Astragali 47%, Herba Leonuri 31%.
In third embodiment of the invention, its mass percent can be: Radix Rehmanniae Preparata 20%, the Radix Astragali 50%, Herba Leonuri 30%.
The present invention also can cooperate other medicines to use together according to different diseases clinically.
As tcm prescription: Radix Rehmanniae Preparata 9 grams, Rhizoma dioscoreae 9 grams, Herba Leonuri 12 grams, Cortex Moutan 9 grams, Cortex Mori 7 grams, the Radix Astragali 20 grams, Herba Pyrolae 5 grams, Semen Plantaginis 9 grams, Rhizoma Acori Graminei 7 grams, Radix Salviae Miltiorrhizae 9 grams, Rhizoma Chuanxiong 9 grams, Semen Persicae 9 grams, Flos Carthami 9 grams, Radix Glycyrrhizae Preparata 6 grams.
The Radix Astragali has tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, holder skin ulcer granulation promoting, the effect of diuretic detumescent.Its composition is sucrose, phlegmatic temperament, aminoacid, choline, betanin, folic acid etc., and the effect that its pharmacology has heart tonifying, diuresis, blood pressure lowering, protects the liver, improves immunity can improve the phagocytic function of leukocyte and mononuclear phagocyte system, increases antibody; Blood vessel dilating, a lot of evidences, the Radix Astragali has the effect of its renal function of better protect to CRF patient.
Radix Rehmanniae Preparata has nourishing the blood and yin, the effect of the kidney invigorating and essence nourishing, its composition contains rehmanin, saccharide, vitamin A, aminoacid, mannitol, alkaloid, fatty acid and irony, it has heart tonifying, diuresis, blood pressure lowering, blood sugar lowering, reaches antiinflammatory action, Radix Rehmanniae Preparata in the characteristics of treatment CRF is: 1, can accelerate the increase of myeloid element, differentiation has significant " hemopoietic " effect, and is effective to the anemia of CRF.2, increase myocardial nutrition blood flow and hypotensive effect, effective to the prophylactic treatment and the hypertension of the cardiovascular event of CRF.3, promote the synthetic of adrenocortical hormone, prevent the effect of adrenal cortex atrophy, the result of the course of disease development of CRF is played optimum effect.4, its " YIN nourishing " mechanism of action plays regulating action to unusual thyroxine state, prevents the secondary hyperparathyroidism to work to CRF patient.5, diuresis " excessively filters theory " and " short twist unbalance theory " these two kinds of theory mechanism work to CRF patient.
Herba Leonuri: the effect that 1, has treatment dog renal failure.As observation index, prove that the Herba Leonuri treatment dog ischemia acute nonfunction of type initial phase (ARF) has remarkable result with creatinine (Cr) blood urea nitrogen (BUN), fractional excretion of filtrated sodium (EFNa), renal blood flow (RBF) and animals survived situation.2, tangible hypotensive activity is arranged.To the effective in cure effect of treatment CRF.
The present invention has following effect to treatment CRF: the activate the phagocytic capacity that strengthens mononuclear phagocyte, remove the IgA deposition, improve the glucose metabolism of CRF, improve glomerular filtration rate, keep CRF phase electrolyte balance, and help to reduce CRF phase hypertension, microcirculation improvement, the glomerule of prevention CRF+renal tubules sclerosis, prevention CRF atherosclerosis is removed retention in the metabolite body, helps to reduce CRF phase vascular hypertension, and potential the somatomedin that can activate renal tissue, promote the cell regeneration of CRF phase kidney cell.Realized the effect that CRF part renal tissue is repaired.
Claims (2)
1. Chinese medicine that is used for the treatment of chronic kidney hypofunction, it is characterized in that: described Chinese medicine is made up of Radix Rehmanniae Preparata, the Radix Astragali, Herba Leonuri, and its percentage by weight is: Radix Rehmanniae Preparata 20%-24%, Radix Astragali 38%-50%, Herba Leonuri 30%-38%.
2. a kind of Chinese medicine that is used for the treatment of chronic kidney hypofunction according to claim 1, it is characterized in that: described Chinese medicine is made up of Radix Rehmanniae Preparata, the Radix Astragali, Herba Leonuri, and its percentage by weight is: Radix Rehmanniae Preparata 20%, the Radix Astragali 42%, Herba Leonuri 38%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2006100303245A CN101130056A (en) | 2006-08-23 | 2006-08-23 | Traditional Chinese medicine used for treating chronic decline of kidney |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2006100303245A CN101130056A (en) | 2006-08-23 | 2006-08-23 | Traditional Chinese medicine used for treating chronic decline of kidney |
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| Publication Number | Publication Date |
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| CN101130056A true CN101130056A (en) | 2008-02-27 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNA2006100303245A Pending CN101130056A (en) | 2006-08-23 | 2006-08-23 | Traditional Chinese medicine used for treating chronic decline of kidney |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104758699A (en) * | 2013-11-27 | 2015-07-08 | 潍坊市现代风湿病研究院 | Preparation method of medicine for treating renal failure |
| CN105327074A (en) * | 2015-11-19 | 2016-02-17 | 王丽 | Pharmaceutical composition with resistance to glomerulosclerosis as well as preparation method and application of pharmaceutical composition |
-
2006
- 2006-08-23 CN CNA2006100303245A patent/CN101130056A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104758699A (en) * | 2013-11-27 | 2015-07-08 | 潍坊市现代风湿病研究院 | Preparation method of medicine for treating renal failure |
| CN104800626A (en) * | 2013-11-27 | 2015-07-29 | 潍坊市现代风湿病研究院 | Preparation method for medicine for treating renal failure |
| CN105327074A (en) * | 2015-11-19 | 2016-02-17 | 王丽 | Pharmaceutical composition with resistance to glomerulosclerosis as well as preparation method and application of pharmaceutical composition |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20080227 |