CN102266520B - Traditional Chinese medicine composition for treating diabetes - Google Patents

Traditional Chinese medicine composition for treating diabetes Download PDF

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CN102266520B
CN102266520B CN2011102072744A CN201110207274A CN102266520B CN 102266520 B CN102266520 B CN 102266520B CN 2011102072744 A CN2011102072744 A CN 2011102072744A CN 201110207274 A CN201110207274 A CN 201110207274A CN 102266520 B CN102266520 B CN 102266520B
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radix
chinese medicine
medicine composition
diabetes
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CN102266520A (en
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王保江
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Abstract

The invention discloses a traditional Chinese medicine composition for treating insulin dependent diabetes and insulin resistant diabetes. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicinal raw materials: ginseng, astragalus root, angelica sinensis, stir fried bighead atractylodes rhizome, tuckahoe, Chinese atractylodes, Chinese yam, kudzu root, prepared rehmannia root, fenugreek, white peony root, beef kidney, cinnamon, wolfberry fruit, magnolia vine fruit and the like. The invention also relates to a preparation method of the traditional Chinese medicine composition, and application thereof in preparing medicaments for treating insulin dependent diabetes and insulin resistant diabetes. The composition disclosed by the invention has multiple advantages of good curative effect, convenience in taking, no adverse reaction and the like.

Description

A kind of Chinese medicine composition for the treatment of diabetes
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of diabetes, relate in particular to a kind of Chinese medicine composition for the treatment of insulin dependent diabetes mellitus (IDDM), insulin resistant type diabetes, the invention still further relates to the Preparation method and use of said composition.
Background technology
Diabetes (Diabetes) are divided the diabetes of type i diabetes, type ii diabetes, gestational diabetes and other specific types.In diabetics, the shared ratio of type ii diabetes is about 95%.
Type i diabetes
Wherein the multiple teenager of being born in of type i diabetes because insulin secretion lacks, relies on exogenous insulin and replenishes to earn a bare living.Child's diabetes also are the common incidence types of type i diabetes.
Type ii diabetes
Insulin is the interior unique blood sugar lowering hormone of the health of human pancreas B emiocytosis.Insulin resistant refers to that surrounding tissue is to the sensitivity reduction of insulin in the body, and peripheral tissues such as muscle, fat promote absorption, conversion, the utilization of glucose that opposing has taken place to insulin.The clinical observation insulin resistant is prevalent in the type ii diabetes, up to about 90%.
Diabetes can cause multiple complications, comprising: melancholy is considered; Vegetative dystonie; Neurological disorder (hand and foot numbness, consciousness paralysis); Cerebral thrombosis; Cerebral infarction; Cataract; Stomatitis; Bronchitis; Dermatosis; Myocardial infarction; Pneumonia; Pulmonary tuberculosis; Liver cirrhosis; Fertility is unusual; Miscarriage; Renal function is unsound; Uremia; Sexual impotence; The female lower body inflammation; Cystitis; Urethritis; Gangrene; Pedopathy becomes (water worm etc.) etc.
The Chinese medicine of prior art also can not satisfy the demand of diabetes and diabetic complication far away on the multiformity of the specificity for the treatment of and medicine.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition for the treatment of insulin dependent diabetes mellitus (IDDM), insulin resistant type diabetes.
Chinese medicine composition of the present invention is made by the raw material of Chinese medicine of following weight ratio:
Radix Ginseng 20 grams, the Radix Astragali 40 grams, Radix Angelicae Sinensis 20 grams, Rhizoma Atractylodis Macrocephalae (parched) 20 grams, Poria 30 grams, Rhizoma Atractylodis 30 grams, Rhizoma Dioscoreae 30 grams, restrain Radix Ophiopogonis 40, Radix Asparagi 30 grams, Fructus Schisandrae Chinensis 20 grams, Fructus Lycii 20 grams, Fructus Corni 30 grams, Radix Rehmanniae Preparata 30 grams, Stigma Maydis 30 grams, Rhizoma Chuanxiong 30 grams, Radix Salviae Miltiorrhizae 30 grams, ghost is seen plumage 50 grams, Radix Trichosanthis 20 grams, Endothelium Corneum Gigeriae Galli 20 grams, Herba Portulacae 20 grams, Radix Rhodiolae 40 grams, the Radix Paeoniae Alba 30 grams, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 20 grams, Pericarpium Citri Reticulatae 20 grams, Fructus Momordicae charantiae 80 grams, the Radix Stemonae 30 grams, Rhizoma Coptidis 20 grams, Cortex Phellodendri 10 grams, Cortex Cinnamomi 20 grams, Aloe 10 grams, Semen Trigonellae 10 grams, Radix Glycyrrhizae 10 grams, Herba Lysimachiae 5 grams, Ramulus Mori 20 grams, Radix Puerariae 10 grams, Spica Prunellae 10 grams, bee pollen 50 grams, Ren Bovis seu Bubali 30 grams, the Radix Aucklandiae 20 grams, Bombyx Batryticatus 20 grams.
Chinese medicine composition of the present invention can be made various types of pharmaceutical preparatioies according to actual needs, for example makes oral liquid, capsule or tablet, and is preferred but be not limited to powder.In order to prepare these preparations, can in compositions of the present invention, add conventional pharmaceutically acceptable auxiliaries as required, selection for adjuvant, those skilled in the art can carry out according to the requirement of dosage form, when for example preparing oral liquid, in the present composition, can add sweeting agent, flavoring agent and antiseptic.Can add binding agent, disintegrating agent etc. during the preparation tablet.For the concrete selection of adjuvant, the present invention's specific restriction useless.
The present invention also relates to prepare the method for Chinese medicine composition of the present invention, described method is to mix behind each raw material pulverizing powdered, perhaps each raw material of Chinese medicine to be extracted, to extract as decocting.If desired, can make required preparation by this area conventional method.
Chinese medicine composition of the present invention has better curative effect for insulin dependent diabetes mellitus (IDDM), insulin resistant type diabetes.Its effect mainly contain following some:
1, Radix Ginseng, the Radix Astragali, Radix Angelicae Sinensis, Rhizoma Atractylodis Macrocephalae (parched), Poria, Rhizoma Atractylodis, Rhizoma Dioscoreae, Radix Puerariae, Radix Rehmanniae Preparata, Semen Trigonellae, the Radix Paeoniae Alba, Ren Bovis seu Bubali, Cortex Cinnamomi, Fructus Lycii, Fructus Schisandrae Chinensis are the basis, benefiting QI and nourishing blood, strengthening spleen, tonifying kidney, the tonifying the lung promoting the circulation of QI, YIN nourishing Yiyang, promoting the production of body fluid to quench thirst, blood sugar lowering, enhancing immunity is the material base of the B cells of pancreas reparative regeneration of excreting insulin.
2, Radix Trichosanthis, Herba Portulacae, Spica Prunellae, Radix Ophiopogonis, Radix Asparagi, Stigma Maydis, Fructus Momordicae charantiae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Pericarpium Citri Reticulatae have heat clearing away, and be antibiotic, eliminates the phlegm; eliminating stagnation, yin nourishing diuresis, promoting the production of body fluid to quench thirst; blood sugar lowering, endocrine regulation, the effects such as B cells of pancreas of protection reparative regeneration excreting insulin.
3, Rhizoma Coptidis, Cortex Phellodendri, the Radix Stemonae, Aloe have heat clearing away antibiotic, antiviral, and catharsis and toxin expelling strengthens effects such as insulin sensitivity.
4, Radix Rhodiolae has the protection internal organs, can protect B cells of pancreas and neurocyte, makes neural self-discipline regulate effects such as insulin secretion.
5, Pollen Pini has endocrine regulation, strengthens metabolism, promotes insulin secretion, and blood sugar lowering is protected blood vessel, prevents and treats the effect of complication.
6, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, ghost are seen plumage, Ramulus Mori, Bombyx Batryticatus, the Radix Aucklandiae, and promoting flow of QI and blood is arranged, and the blood fat reducing endogenous wind stopping is promoted blood circulation, and vessel softening is prevented and treated effects such as complication.
7, Endothelium Corneum Gigeriae Galli, Herba Lysimachiae, having sugar, dissipating blood stasis, effects such as diuresis.
A kind of Chinese medicine composition for the treatment of diabetes is specially in order to recover pancreatic function, improves self blood sugar lowering ability; fundamentally treat diabetes design; after taking medicine, the B cells of pancreas of excreting insulin is protected, reparative regeneration, the quantity of B cells of pancreas is constantly increased; up to recovering fully; after the recovery from illness, the same with the normal person, no longer take any antidiabetic drug; and blood glucose value is normal value, is difficult for bounce-back.
The specific embodiment
Embodiment
Radix Ginseng 20 grams, the Radix Astragali 40 grams, Radix Angelicae Sinensis 20 grams, Rhizoma Atractylodis Macrocephalae (parched) 20 grams, Poria 30 grams, Rhizoma Atractylodis 30 grams, Rhizoma Dioscoreae 30 grams, restrain Radix Ophiopogonis 40, Radix Asparagi 30 grams, Fructus Schisandrae Chinensis 20 grams, Fructus Lycii 20 grams, Fructus Corni 30 grams, Radix Rehmanniae Preparata 30 grams, Stigma Maydis 30 grams, Rhizoma Chuanxiong 30 grams, Radix Salviae Miltiorrhizae 30 grams, ghost is seen plumage 50 grams, Radix Trichosanthis 20 grams, Endothelium Corneum Gigeriae Galli 20 grams, Herba Portulacae 20 grams, Radix Rhodiolae 40 grams, the Radix Paeoniae Alba 30 grams, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 20 grams, Pericarpium Citri Reticulatae 20 grams, Fructus Momordicae charantiae 80 grams, the Radix Stemonae 30 grams, Rhizoma Coptidis 20 grams, Cortex Phellodendri 10 grams, Cortex Cinnamomi 20 grams, Aloe 10 grams, Semen Trigonellae 10 grams, Radix Glycyrrhizae 10 grams, Herba Lysimachiae 5 grams, Ramulus Mori 20 grams, Radix Puerariae 10 grams, Spica Prunellae 10 grams, bee pollen 50 grams, Ren Bovis seu Bubali 30 grams, the Radix Aucklandiae 20 grams, Bombyx Batryticatus 20 grams.
Preparation method: will mix behind each raw material pulverizing powdered.
Usage and dosage: powder face electuary, day clothes twice, each 10 grams.
Points for attention:
1, quit smoking, wine and pungent, raw and cold, greasy food.
2, avoid X-ray.Avoid sweet food.
3, severe patient is in drug administration process, make blood glucose that a stable process be arranged according to blood glucose value other antidiabetic drugs of little by little stopping using.
Untoward reaction: do not find as yet.
The clinical example of curative effect
1, the precious post man of king is 51 years old
Wang Baozhu (identification card number: 23100196002292052), the man, 51 years old, disease: fasting blood sugar 17.3mmol/L before the treatment, 2008 through four months the treatment after fasting blood sugar be down to 5.4mmol/L, fasting blood sugar was down to 4.3mmol/L in 2011, triennial hypoglycemic medicine and the insulin of not taking any other so far.
2, the poplar man is 48 years old
Poplar, the man, 48 years old, the driver, diabetic history 1 year, 2007 is diabetes at the red flag hospital diagnosis, fasting blood sugar 14.4mmol/L, through we's treatment, fasting blood sugar is down to 5.6mmol/L after two months, and the working of having fully recovered is followed up a case by regular visits to normal after 1 year.
3, the Wang man is 30 years old
The Wang, 30 years old, diabetic history 25 years, the military region, Mudanjiang in 1994 hospital diagnosis is diabetes, fasting blood sugar 14.6mmol/L, the big hemoptysis of complication pulmonary tuberculosis in 2005.Mudanjiang tumour hospital is diagnosed as diabetes and complication again, fasting blood sugar 15.1mmol/L, took in 2005 we treatment add Western medicine treating pulmonery tuberculosis connection medicine after three months pulmonary tuberculosis cure, without Western medicine, single with we's treatment diabetes after half a year fasting blood sugar be down to 5.1mmol/L, continue treatment after one month the patient fully recover.
4, the grandson man is 71 years old
Grandson, 71 years old, diabetic history 32 years, repeatedly by First People's Hospital, Mudanjiang diagnosing diabetes, external injection protamine zine insulin---morning, 16 units; Evening, 15 units; Fasting blood sugar (13.5~18.7) mmol/L, annual being in hospital 2~4 times, insulin injection quantity began decrement, treated insulin injection---morning after 1 year, 3 units with we's treatment after two months in 2007; Evening, 2 units; Fasting blood sugar (3.8~5.4) mmol/L, sliding injury when having a bath, lumbar soft tissue injury, blood glucose value rebounds to some extent after the X of hospital takes pictures.
5, the Zhang man is 45 years old
Zhang, 45 years old, diabetic history 8 years, First People's Hospital, Mudanjiang is diagnosed as diabetes, fasting blood sugar 11.4mmol/L, sb.'s illness took a favorable turn after we treat one month, doing well,improving.

Claims (5)

1. a Chinese medicine composition for the treatment of diabetes is characterized in that, it is to be made by the raw material of Chinese medicine of following weight ratio:
Radix Ginseng 20 grams, the Radix Astragali 40 grams, Radix Angelicae Sinensis 20 grams, Rhizoma Atractylodis Macrocephalae (parched) 20 grams, Poria 30 grams, Rhizoma Atractylodis 30 grams, Rhizoma Dioscoreae 30 grams, restrain Radix Ophiopogonis 40, Radix Asparagi 30 grams, Fructus Schisandrae Chinensis 20 grams, Fructus Lycii 20 grams, Fructus Corni 30 grams, Radix Rehmanniae Preparata 30 grams, Stigma Maydis 30 grams, Rhizoma Chuanxiong 30 grams, Radix Salviae Miltiorrhizae 30 grams, ghost is seen plumage 50 grams, Radix Trichosanthis 20 grams, Endothelium Corneum Gigeriae Galli 20 grams, Herba Portulacae 20 grams, Radix Rhodiolae 40 grams, the Radix Paeoniae Alba 30 grams, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 20 grams, Pericarpium Citri Reticulatae 20 grams, Fructus Momordicae charantiae 80 grams, the Radix Stemonae 30 grams, Rhizoma Coptidis 20 grams, Cortex Phellodendri 10 grams, Cortex Cinnamomi 20 grams, Aloe 10 grams, Semen Trigonellae 10 grams, Radix Glycyrrhizae 10 grams, Herba Lysimachiae 5 grams, Ramulus Mori 20 grams, Radix Puerariae 10 grams, Spica Prunellae 10 grams, bee pollen 50 grams, Ren Bovis seu Bubali 30 grams, the Radix Aucklandiae 20 grams, Bombyx Batryticatus 20 grams.
2. Chinese medicine composition according to claim 1 is characterized in that, described Chinese medicine composition can be prepared into various clinical acceptable forms by practice of pharmacy.
3. Chinese medicine composition according to claim 2 is characterized in that, described dosage form is powder, capsule, tablet or oral liquid.
4. the preparation method of the described Chinese medicine composition of claim 1 is characterized in that, with mixing behind each raw material pulverizing powdered, perhaps each raw material of Chinese medicine is extracted.
5. the application of the described Chinese medicine composition of claim 3 in the medicine of preparation treatment insulin dependent diabetes mellitus (IDDM), insulin resistant type diabetes.
CN2011102072744A 2011-07-25 2011-07-25 Traditional Chinese medicine composition for treating diabetes Expired - Fee Related CN102266520B (en)

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CN102488815B (en) * 2011-12-15 2013-06-12 山东大学 Buccal tablet for reducing blood sugar
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CN103301285A (en) * 2013-06-05 2013-09-18 吉林省宏久生物科技股份有限公司 Traditional Chinese medicinal formula for treating diabetic
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CN104544084B (en) * 2015-01-19 2016-06-08 孙宁 A kind of health food for diabetics
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CN107281359A (en) * 2016-06-03 2017-10-24 王家强 A kind of Chinese medicine composition for being used for treating diabetes
CN106511805A (en) * 2016-11-04 2017-03-22 张超英 Preparation method for traditional Chinese medicine composition and traditional Chinese medicine capsule used for treating diabetes
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CN110876717A (en) * 2019-12-10 2020-03-13 大连海宝生物技术有限公司 Preparation method of product capable of stabilizing blood sugar
CN112717077A (en) * 2021-01-18 2021-04-30 胡其勇 Coarse grain powder for treating type II diabetes
CN115251388A (en) * 2022-08-09 2022-11-01 上海仁心善医健康科技有限公司 Composition for assisting in reducing blood sugar and food supplement thereof
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