CN103652105A - Chinese toon herbal tea with effect of reducing blood sugar - Google Patents
Chinese toon herbal tea with effect of reducing blood sugar Download PDFInfo
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- CN103652105A CN103652105A CN201210321081.6A CN201210321081A CN103652105A CN 103652105 A CN103652105 A CN 103652105A CN 201210321081 A CN201210321081 A CN 201210321081A CN 103652105 A CN103652105 A CN 103652105A
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Abstract
The invention discloses Chinese toon herbal tea with an effect of reducing blood sugar. The Chinese toon herbal tea comprises the following raw materials in parts by weight: 1-4 parts of Taihe Chinese toon, 1-4 parts of angelica keiskei and 1-5 parts of gynostemma pentaphylla. The invention also discloses a method for preparing the Chinese toon herbal tea.
Description
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Technical field
The present invention relates to a kind of careless tea, more particularly, relate to a kind of tribute Chinese toon Herb Tea with blood sugar reducing function.
Background technology
In the last few years, along with improving constantly of people's living standard, the change of dietary structure and the progress of diagnostic techniques, the incidence of disease of diabetes also presents the trend rising year by year.According to the report of international diabetes conference in 2011, the whole world has 3.66 hundred million patients at present, is equivalent to the Middle East and African population summation, also has 2.8 hundred million impaired glucose tolerances (IGT) crowd, Er China, the ill population of diabetes is approximately 2,000 ten thousand---and-4,000 ten thousand.Diabetes have become the disease of the third-largest threat human health after angiocardiopathy, tumour.The medical institutions of countries in the world have dropped into a large amount of manpower and financial resources in the research of diabetes, but at present the cause of disease and the pathogenesis of diabetes and complication are illustrated not yet completely, and the means of its prevention and treatment all have much room for improvement.Therefore set up desirable diabetes model for the cause of disease, pathogenesis, the treatment of further investigation diabetes and prevent most important.
Diabetes animal model sets up that to be divided into heredity spontaneous and bring out two classes.The external diabetes study animal models that adopt are hereditary spontaneous models more, as BB mouse, NOD mouse, db/db mouse, NYS mouse
[3]deng, source difficulty and expensive.The method of bringing out modeling mainly contain excision pancreas islet method, chemicals revulsion as alloxan and Streptozotocin, virus infections, fatten etc.It is simple to operation that diabetes model is set up in chemical induction, is widely used.STZ(Streptozotocin streptozotocin) the mechanism of action is selective injury B cell, and trigger cell is downright bad, and then causes the blood insulin companion's blood sugar that declines in various degree to raise, and forms IDDM.
At present, the main method for the treatment of diabetes is to take Chinese and Western medicine.Doctor trained in Western medicine adopts the medicine of aldose reductase inhibition, biguanides and sulfonylureas mostly, these drug side-effects are large, price is relative also higher, though its drug effect is worth certainly, but this type of medicine has its limitation and bad reaction, as long-term use, cause the complication such as hypoglycemia, renal hypofunction, cardiovascular system.Comparatively speaking, Chinese medicine is subject to modern's welcome with the advantage such as treat both principal and secondary aspect of disease, side effect is little always deeply, but Traditional chinese medicine medicament treatment cycle is long, takes effect slow, needs to decoct while taking Chinese medicine, carries inconvenience.Therefore, the focus that the Chinese medicine antidiabetic drug easy, toxic and side effect is little becomes many focus of attentions is carried in exploitation.
Summary of the invention
The object of this invention is to provide a kind of tribute Chinese toon Herb Tea with blood sugar reducing function.
Another object of the present invention is to provide the method for the above-mentioned tribute Chinese toon Herb Tea of preparation.
Another object of the present invention is to provide the method for the tea of the above-mentioned tribute Chinese toon Herb Tea of preparation.
Specifically, the invention provides a kind of tribute Chinese toon Herb Tea with blood sugar reducing function, it comprises the raw material of following parts by weight: Taihe county Chinese toon 1-4 part, tomorrow leaf 1-4 part, gynostemma pentaphylla 1-5 part.
Preferably, can comprise the raw material of following weight fraction: 1 part, Taihe county Chinese toon, 2 parts of tomorrow leafs, 1 part of gynostemma pentaphylla.
A method of preparing above-mentioned tribute Chinese toon Herb Tea, can comprise the following steps: Taihe county Chinese toon, and before annual grain rains, the fresh Chinese toon bud of harvesting, chooses decontamination, dries to moisture content and is less than 8.5%; Tomorrow leaf, chooses clean leaf stalk, anthocaulus and spare impurity, dries to moisture content and is less than 8.5%; Gynostemma pentaphyllum leaf, after receiving, airing to moisture content is less than 8.5%, puts shady and cool airtight place preservation; The bulk drug of above-mentioned each weight portion is pulverized, crossed 40 order mesh screens, the weight fraction with 3g after sterilization packs pouch-packaged into, obtains tribute Chinese toon Herb Tea.
A method of preparing the tea of above-mentioned tribute Chinese toon Herb Tea can be got a small bag tea when drinking, and with the 80-90 ℃ of boiling water of 200-300mL, brews 2 minutes.
The combination principle of tribute Chinese toon Herb Tea of the present invention and each component property of medicine are as follows:
Chinese toon, has another name called mountain Chinese toon, Hu Mushu, tiger eye etc., belongs to Meliaceae Cedrela, is the seeds of the peculiar preciousness of China and traditional famous and precious woody vegetables.Chinese toon bitter warm in nature, nontoxic, return spleen, stomach warp.Have hemostasis controlling nocturnal emission with astringent drugs, heat-clearing is gone dry, and the effect of eliminating inflammation and expelling toxin cures mainly n and V, loses the appetite, has loose bowels, the disease such as dysentery, swollen ulcer drug, and preventing tumor in advance.Modern medicine study also confirms, Chinese toon has beauty treatment, antibiotic effect.With fresh Chinese toon bud, smashing taking juice wipes one's face, can treat face disease, Glycerin, there is good skin maintenance effect, improve body's immunity, moist skin, Chinese toon contains the materials such as abundant vitamin C, carrotene, contributes to enhanced machine body immunity function, and have the effect well lubricating the skin and muscle, be the good food of health and beauty.
Angelica Keiskei, another name tomorrow leaf, eight zhang of grass, there is the very abundant health that maintains, prevent aging necessary various vitamin, mineral matter, trace element, in Angelica Keiskei, main component is chalcones and coumarin kind compound, wherein the highest with the content of chalcones uranidin compound, and Angelica Keiskei chalcone is when high dose, can make human liver cancer cell (SMMC-7721) cellular morphology change obviously, cell survival rate significantly reduces, and the growth of SMMC-7721 cell is had to inhibitory action.
Gynostemma pentaphylla, gynostemma pentaphylla is the nearly 20 years health product of just finding, as far back as the Spring and Autumn and the Warring States Periods, some work as edible wild herbs gynostemma pentaphylla and allay one's hunger.Until 1406 bright eternally happy 4 years Zhu Su show < < Herbal for Relief of Famines > >, gynostemma pentaphylla is formally written into.In recent years experimental studies results shows that gynostemma pentaphylla contains the Multiple components such as gynosaponin, amino acid, protein, fat, flavonoids, carbohydrate, inorganic elements, cellulose and vitamin, gypenoside can reduce experimental atherosclerosis rats blood fat, correct hepar damnification, suppress lipid peroxidation, correct the disorders of lipid metabolism that experimental hyperlipidemia causes.
Experimental study shows, by carrying out gavage with tribute Chinese toon Herb Tea extract of the present invention, model mice blood sugar declines to some extent, although fall does not have chemical sugar-lowering medicine obvious, also has good blood sugar reducing function.Although this illustrates that tribute Chinese toon Herb Tea of the present invention can not show maximum drug effect in a short time completely, slowly nurses one's health as a kind of tea-drinking, can play and progressively fall hypoglycemic effect.And careless tea of the present invention is compared with drug products in the market, have advantages of toxic and side effect little, can long-term taking.
The specific embodiment
Below by embodiment, describing embodiments of the present invention, for one of ordinary skill in the art appreciates that these specific embodiments only show the enforcement technical scheme of selecting in order to reach object of the present invention, is not the restriction to technical scheme.According to instruction of the present invention, in conjunction with prior art, to the improvement of technical solution of the present invention, be obvious, all belong to the scope of protection of the invention.
Embodiment 1
Raw material: 1 part, Taihe county Chinese toon, 1 part of tomorrow leaf, 1 part of gynostemma pentaphylla
Preparation method:
Taihe county Chinese toon, plucked fresh Chinese toon bud before grain rains, choose decontamination, dried to moisture content and was less than 8.5%; Tomorrow leaf, chooses clean leaf stalk, anthocaulus and spare impurity, dries to moisture content and is less than 8.5%; Gynostemma pentaphyllum leaf, after receiving, airing to moisture content is less than 8.5%, puts shady and cool airtight place preservation; The bulk drug of above-mentioned each weight portion is pulverized, crossed 40 order mesh screens, the weight fraction with 3g after sterilization packs pouch-packaged into, obtains tribute Chinese toon Herb Tea.
Embodiment 2
Raw material: 4 parts, Taihe county Chinese toon, 4 parts of tomorrow leafs, 5 parts of gynostemma pentaphylla
Preparation method is identical with embodiment 1.
Embodiment 3
Raw material: 1 part, Taihe county Chinese toon, 2 parts of tomorrow leafs, 1 part of gynostemma pentaphylla
Preparation method is identical with embodiment 1.
Wherein, the raw material sources that use in embodiment 1-3 and following zoopery are: Taihe county Chinese toon, purchased from Fuyang Yilong Healthcare Food Technology Co., Ltd.; Tomorrow leaf, gynostemma pentaphylla, all purchased from heavenly steed (Anhui) prepared slices of Chinese crude drugs Science and Technology Ltd..
Zoopery
1 diabetic mice model building
First, to 60 experiment mice numberings, weigh respectively body weight separately and also dock and get the blood sugar concentration under hematometry mouse normal condition, record data.Then to mouse fasting 12h, during fasting, can't help water.
Get 0.1mol/L citrate buffer solution (pH 4-5) 10ml, be placed under ice bath state stand-by.Press the concentration of 250mg/kg, according to the concrete body weight of mouse, take the Streptozotocin of different amounts, be placed in stand-by under same ice bath environment (needing lucifuge to process).
The citrate buffer solution 0.3ml getting respectively after ice bath dissolves STZ, with 1ml syringe, mouse is carried out to single intraperitoneal injection.STZ after dissolving must complete injection in 30min.For preventing the generation of dead mouse, after injection, should note following some: 1. must guarantee enough amounts of drinking water: 2. hyperglycaemia and hypoglycemia all can cause dead mouse, avoid dead mouse by insulin injection or the temporary transient sugar of mending, to mend the mode that sugar can be taked gavage glucose: 3. to prevent that animal from killing each other; 4. for protecting from infection, duty to change bedding and padding.
1.1.1 become mould standard: 72h mouse blood sugar value after use blood glucose meter survey administration, the non-fasting blood-glucose >11.0mmol/L of usining becomes mould standard as diabetic mice.
1.2 medicine gavage treatment
1.2.1 gavage medicine preparation
1.2.1.1 test the preparation of gavage medicine: weigh Chinese toon tea 3g, be soaked in 200ml distilled water, be placed in 40 ℃ of thermostat water bath 24h, filter, get filtrate, with rotary evaporator, be concentrated into 10ml.Wherein, Taihe county Chinese toon (0.75g) is 1 part; 2 parts of tomorrow leafs (1.5g); 1 part of gynostemma pentaphylla (0.75g).
1.2.1.2 positive control gavage medicine preparation: weigh the metformin hydrochloride tablet powder of different amounts according to positive controls Mouse Weight according to 800mg/kg concentration, dissolve and obtain positive controls gavage medicine with 0.4ml distilled water.
1.2.2 the gavage of dividing into groups: the successful diabetic mice of modeling is divided into 3 groups at random, is respectively model group, Metformin hydrochloride positive controls and experiment Chinese medicine water extraction mixture group.During gavage, every gavage of model group 0.9% physiological saline 0.4ml; Every gavage positive control gavage medicine 0.4ml of positive controls; Every gavage experiment gavage medicine 0.4ml of experimental group.Morning and evening every day interval 12h gavage 1 time, continuous gavage 7d, fasting 6h after last administration, docking is got blood and is surveyed mouse blood sugar level on an empty stomach.
Result:
2.1 mouse become mould situation
After administration 3d, weigh the body weight of all experiment mices, and the mode that adopts docking to get blood is measured mouse tail venous blood sugar level by blood glucose meter, measurement result shows, there are 47 mouse blood sugar concentration >11.0mmol/L, be diabetes model, other 13 mouse different time after injection is all dead.There is obviously more foods, many drinks, diuresis and Body weight loss in the diabetic mice after Cheng Mo.
The impact of 2.2 water extracts on mouse blood sugar level
Successful 47 mouse of modeling are divided into 3 groups at random.Carry out respectively as stated above gavage, fasting 6h after last administration, docking is got blood and is surveyed mouse tail venous blood sugar level.Measurement result demonstration, uses after water extract and melbine gavage continuously, and blood glucose in diabetic mice level obviously reduces, and model group mouse blood sugar level is higher.Result is as shown in table 1 below.
The impact of table 1. medicine on blood glucose in diabetic mice
Note: HI represents that blood sugar concentration is higher than 27.0mmol/L.
Experimental study shows, with tribute Chinese toon Herb Tea water extract, carries out gavage, and model mice blood sugar declines to some extent, although fall does not have chemical sugar-lowering medicine obvious, with control group significant difference.Although this illustrates that tribute Chinese toon Herb Tea of the present invention can not show maximum drug effect in a short time completely, slowly nurses one's health as a kind of tea-drinking, can play and progressively fall hypoglycemic effect.And careless tea of the present invention is compared with drug products in the market, have that toxic and side effect is little, taking convenience, can long-term taking etc. advantage.
The above, it is only preferred embodiment of the present invention, not the present invention is done to any formal and substantial restriction, all those skilled in the art, do not departing within the scope of technical solution of the present invention, when utilizing disclosed above technology contents, and the equivalent variations of a little change of making, modification and differentiation is equivalent embodiment of the present invention; Meanwhile, any change that all foundations essence technology of the present invention is done above embodiment, modification and differentiation, all still belong in the scope of technical scheme of the present invention.
Claims (4)
1. a tribute Chinese toon Herb Tea with blood sugar reducing function, is characterized in that, comprises the raw material of following weight portion: Taihe county Chinese toon 1-4 part, tomorrow leaf 1-4 part, gynostemma pentaphylla 1-5 part.
2. tribute Chinese toon Herb Tea according to claim 1, is characterized in that, comprises the raw material of following weight portion: 1 part, Taihe county Chinese toon, 2 parts of tomorrow leafs, 1 part of gynostemma pentaphylla.
3. a method of preparing tribute Chinese toon Herb Tea as claimed in claim 1 or 2, is characterized in that, comprises the following steps: Taihe county Chinese toon, and before annual grain rains, the fresh Chinese toon bud of harvesting, chooses decontamination, dries to moisture content and is less than 8.5%; Tomorrow leaf, chooses clean leaf stalk, anthocaulus and spare impurity, dries to moisture content and is less than 8.5%; Gynostemma pentaphyllum leaf, after receiving, airing to moisture content is less than 8.5%, puts shady and cool airtight place preservation; The raw material of above-mentioned each weight portion is pulverized, crossed 40 order mesh screens, the weight fraction with 3g after sterilization packs pouch-packaged into, obtains tribute Chinese toon Herb Tea.
4. a method of preparing the tea of tribute Chinese toon Herb Tea as claimed in claim 3, is characterized in that, while drinking, gets a small bag tea, with the 80-90 ℃ of boiling water of 200-300mL, brews 2 minutes.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1283394A (en) * | 1999-08-06 | 2001-02-14 | 刘自福 | Chinese toon tea and preparing process thereof |
| CN1366831A (en) * | 2002-01-30 | 2002-09-04 | 刘志强 | Chinese toon tea and its preparation method |
| CN1397185A (en) * | 2001-07-18 | 2003-02-19 | 王珠山 | Gynostemma pentaphyllum tea and its prodn. method |
| CN102018066A (en) * | 2009-09-16 | 2011-04-20 | 郝敬方 | Composite cactus tea |
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|---|---|---|---|---|
| CN1283394A (en) * | 1999-08-06 | 2001-02-14 | 刘自福 | Chinese toon tea and preparing process thereof |
| CN1397185A (en) * | 2001-07-18 | 2003-02-19 | 王珠山 | Gynostemma pentaphyllum tea and its prodn. method |
| CN1366831A (en) * | 2002-01-30 | 2002-09-04 | 刘志强 | Chinese toon tea and its preparation method |
| CN102018066A (en) * | 2009-09-16 | 2011-04-20 | 郝敬方 | Composite cactus tea |
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