CN103652105B - Chinese toon herbal tea with effect of reducing blood sugar - Google Patents
Chinese toon herbal tea with effect of reducing blood sugar Download PDFInfo
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- CN103652105B CN103652105B CN201210321081.6A CN201210321081A CN103652105B CN 103652105 B CN103652105 B CN 103652105B CN 201210321081 A CN201210321081 A CN 201210321081A CN 103652105 B CN103652105 B CN 103652105B
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses Chinese toon herbal tea with an effect of reducing blood sugar. The Chinese toon herbal tea comprises the following raw materials in parts by weight: 1-4 parts of Taihe Chinese toon, 1-4 parts of angelica keiskei and 1-5 parts of gynostemma pentaphylla. The invention also discloses a method for preparing the Chinese toon herbal tea.
Description
Technical field
The present invention relates to a kind of careless tea, more particularly, relate to a kind of tribute Chinese toon Herb Tea with blood sugar reducing function.
Background technology
In the last few years, along with improving constantly of people's living standard, the change of dietary structure and the progress of diagnostic techniques, the incidence of disease of diabetes also presents the trend risen year by year.According to the report of international diabetes conference in 2011, the whole world has 3.66 hundred million patients at present, is equivalent to the Middle East and African population summation, also has 2.8 hundred million impaired glucose tolerances (IGT) crowd, and in China, the ill population of diabetes is approximately 2,000 ten thousand----4,000 ten thousand.Diabetes have become the disease of the third-largest threat human health after angiocardiopathy, tumour.The medical institutions of countries in the world have dropped into a large amount of manpower and financial resources in the research of diabetes, but the cause of disease of current diabetes and complication and pathogenesis are illustrated not yet completely, and the means of its prevention and therapy all have much room for improvement.Therefore desirable diabetes model is set up for furtheing investigate the cause of disease, pathogenesis, the treatment of diabetes and preventing most important.
Diabetes animal model is set up and is divided into heredity spontaneous and bring out two classes.The animal model of the many employings of external diabetes study is hereditary spontaneous model, as BB mouse, NOD mouse, db/db mouse, NYS mouse
[3]deng, source is difficult and expensive.The method of bringing out modeling mainly contain excision pancreas islet method, chemicals revulsion as alloxan and Streptozotocin, virus infections, fatten.It is simple to operation that diabetes model is set up in chemical induction, is widely used.STZ(Streptozotocin streptozotocin) the mechanism of action be selective injury B cell, trigger cell is downright bad, and then causes the blood insulin companion's blood sugar that declines in various degree to raise, and forms IDDM.
At present, the main method for the treatment of diabetes takes Chinese and Western medicine.Doctor trained in Western medicine adopts the medicine of AR enzyme level, biguanides and sulfonylureas mostly, these drug side-effects are large, price is relative also higher, though its drug effect is worth certainly, but this type of medicine has its limitation and bad reaction, cause the complication such as hypoglycemia, renal hypofunction, cardiovascular system as Long-Time Service.Comparatively speaking, Chinese medicine always to treat both principal and secondary aspect of disease, the advantage such as side effect is little deeply by the welcome of modern, but Traditional chinese medicine medicament treatment cycle is long, takes effect slow, needs decoction when taking Chinese medicine, carries inconvenience.Therefore, easy, that toxic and side effect is little Chinese medicine antidiabetic drug becomes many focus of attentions focus is carried in exploitation.
Summary of the invention
The object of this invention is to provide a kind of tribute Chinese toon Herb Tea with blood sugar reducing function.
Another object of the present invention is to provide the method preparing above-mentioned tribute Chinese toon Herb Tea.
Another object of the present invention is to provide the method for the tea preparing above-mentioned tribute Chinese toon Herb Tea.
Specifically, the invention provides a kind of tribute Chinese toon Herb Tea with blood sugar reducing function, it comprises the raw material of following parts by weight: Taihe county Chinese toon 1-4 part, tomorrow leaf 1-4 part, gynostemma pentaphylla 1-5 part.
Preferably, the raw material of following weight fraction can be comprised: 1 part, Taihe county Chinese toon, tomorrow leaf 2 parts, gynostemma pentaphylla 1 part.
Prepare a method for above-mentioned tribute Chinese toon Herb Tea, can comprise the following steps: Taihe county Chinese toon, plucked fresh Chinese toon bud before annual grain rains, pick decontamination, dry to moisture content and be less than 8.5%; Tomorrow leaf, picks clean leaf stalk, anthocaulus and spare impurity, dries to moisture content and is less than 8.5%; Gynostemma pentaphyllum leaf, after receiving, airing is less than 8.5% to moisture content, puts shady and cool airtight place preservation; The bulk drug of above-mentioned each weight portion is pulverized, crosses 40 order mesh screens, load pouch-packaged with the weight fraction of 3g after sterilization, namely obtain tribute Chinese toon Herb Tea.
Preparing a method for the tea of above-mentioned tribute Chinese toon Herb Tea, when drinking, a small bag tea can be got, brew 2 minutes with the 80-90 DEG C of boiling water of 200-300mL.
Combination principle and each component property of medicine of tribute Chinese toon Herb Tea of the present invention are as follows:
Chinese toon, has another name called mountain Chinese toon, Hu Mushu, brave eye etc., and belonging to Meliaceae Cedrela, is the seeds of the peculiar preciousness of China and traditional famous and precious woody vegetables.Chinese toon bitter warm in nature, nontoxic, return spleen, stomach warp.Have hemostasis controlling nocturnal emission with astringent drugs, heat-clearing is gone dry, effect of eliminating inflammation and expelling toxin, cures mainly n and V, loses the appetite, has loose bowels, the disease such as dysentery, swollen ulcer drug, and can preventing tumor in advance.Modern medicine study also confirms, Chinese toon has beauty treatment, antibiotic effect.Smash taking juice with fresh Chinese toon bud to wipe one's face, face disease, Glycerin can be treated, there is good skin maintenance effect, improve body's immunity, moist skin, Chinese toon contains the materials such as abundant vitamin C, carrotene, contributes to enhanced machine body immunity function, and have the effect well lubricated the skin and muscle, be the good food of health and beauty.
Angelica Keiskei, another name tomorrow leaf, eight zhang of grass, there is very abundant maintenance health, prevent aging necessary various vitamin, mineral matter, trace element, in Angelica Keiskei, main component is chalcones and coumarin kind compound, wherein the highest with the content of chalcones uranidin compound, and Angelica Keiskei chalcone is when high dose, human liver cancer cell (SMMC-7721) cellular morphology can be made to change obviously, cell survival rate significantly reduces, and has inhibitory action to the growth of SMMC-7721 cell.
Gynostemma pentaphylla, gynostemma pentaphylla is the nearly 20 years health product just found, as far back as the Spring and Autumn and the Warring States Periods, some work as edible wild herbs gynostemma pentaphylla and allay one's hunger.Until 1406 bright eternally happy 4 years Zhu's herbal for Relief of Famines that Su shows, gynostemma pentaphylla is formally loaded into.In recent years experimental studies results shows that gynostemma pentaphylla contains the Multiple components such as gynosaponin, amino acid, protein, fat, flavonoids, carbohydrate, inorganic elements, cellulose and vitamin, gypenoside can reduce experimental atherosclerosis rats blood fat, correct hepar damnification, anti-lipid peroxidation, corrects the disorders of lipid metabolism that experimental hyperlipidemia causes.
Experimental study shows, by carrying out gavage with tribute Chinese toon Herb Tea extract of the present invention, model mice blood sugar declines to some extent, although fall does not have chemical sugar-lowering medicine obvious, also has good blood sugar reducing function.Although this illustrates that tribute Chinese toon Herb Tea of the present invention can not show maximum drug effect in a short time completely, slowly nurse one's health as a kind of tea-drinking, can play and progressively fall hypoglycemic effect.And, careless tea of the present invention drug products more in the market, have toxic and side effect little, can the advantage of long-term taking.
Detailed description of the invention
Describing embodiments of the present invention below by embodiment, for one of ordinary skill in the art appreciates that these specific embodiments only show the enforcement technical scheme selected to reach object of the present invention, is not the restriction to technical scheme.According to instruction of the present invention, be obvious in conjunction with the improvement of prior art to technical solution of the present invention, all belong to the scope of protection of the invention.
Embodiment 1
Raw material: 1 part, Taihe county Chinese toon, tomorrow leaf 1 part, gynostemma pentaphylla 1 part
Preparation method:
Taihe county Chinese toon, plucked fresh Chinese toon bud before grain rains, picks decontamination, dried to moisture content and was less than 8.5%; Tomorrow leaf, picks clean leaf stalk, anthocaulus and spare impurity, dries to moisture content and is less than 8.5%; Gynostemma pentaphyllum leaf, after receiving, airing is less than 8.5% to moisture content, puts shady and cool airtight place preservation; The bulk drug of above-mentioned each weight portion is pulverized, crosses 40 order mesh screens, load pouch-packaged with the weight fraction of 3g after sterilization, namely obtain tribute Chinese toon Herb Tea.
Embodiment 2
Raw material: 4 parts, Taihe county Chinese toon, tomorrow leaf 4 parts, gynostemma pentaphylla 5 parts
Preparation method is identical with embodiment 1.
Embodiment 3
Raw material: 1 part, Taihe county Chinese toon, tomorrow leaf 2 parts, gynostemma pentaphylla 1 part
Preparation method is identical with embodiment 1.
Wherein, the raw material sources used in embodiment 1-3 and following zoopery are: Taihe county Chinese toon, purchased from Fuyang Yilong Healthcare Food Technology Co., Ltd.; Tomorrow leaf, gynostemma pentaphylla, all purchased from heavenly steed (Anhui) prepared slices of Chinese crude drugs Science and Technology Ltd..
Zoopery
1 diabetic mouse model is built
First to 60 experiment mices numbering, weigh respective body weight respectively and the blood sugar concentration under hematometry mouse normal condition is got in docking, record data.Then to mouse fasting 12h, during fasting, can't help water.
Get 0.1mol/L citrate buffer solution (pH 4-5) 10ml, stand-by under being placed in ice bath state.By the concentration of 250mg/kg, take the Streptozotocin of different amount according to the concrete body weight of mouse, stand-by under being placed in same ice bath environment (needing lucifuge process).
Get the citrate buffer solution 0.3ml after ice bath respectively and dissolve STZ, with 1ml syringe, single intraperitoneal injection is carried out to mouse.STZ after dissolving must complete injection in 30min.For preventing the generation of dead mouse, should note after injection following some: 1. must ensure enough amounts of drinking water: 2. hyperglycaemia and hypoglycemia all can cause dead mouse, avoid dead mouse can mend sugar by insulin injection or temporarily, mend sugar and can take the mode of gavage glucose: 3. prevent animal from killing each other; 4. for protecting from infection, duty to change bedding and padding.
1.1.1 mould standard is become: 72h mouse blood sugar value after use blood glucose meter survey administration, becomes mould standard using non-fasting blood-glucose >11.0mmol/L as diabetic mice.
1.2 medicine gavage is treated
1.2.1 gavage medicine is prepared
1.2.1.1 test the preparation of gavage medicine: weigh Chinese toon tea 3g, be soaked in 200ml distilled water, be placed in 40 DEG C of thermostat water bath 24h, filter, get filtrate, be concentrated into 10ml with rotary evaporator.Wherein, 1 part, Taihe county Chinese toon (0.75g); Tomorrow leaf (1.5g) 2 parts; Gynostemma pentaphylla (0.75g) 1 part.
1.2.1.2 positive control gavage medicine preparation: the metformin hydrochloride tablet powder weighing different amount according to positive controls Mouse Weight according to 800mg/kg concentration, dissolves with 0.4ml distilled water and obtains positive controls gavage medicine.
1.2.2 to divide into groups gavage: successful for modeling diabetic mice is divided into 3 groups at random, is respectively model group, Metformin hydrochloride positive controls and experiment Chinese medicine water extraction mixture group.During gavage, model group every gavage 0.9% physiological saline 0.4ml; Positive controls every gavage positive control gavage medicine 0.4ml; Experimental group every gavage experiment gavage medicine 0.4ml.Morning and evening every day interval 12h gavage 1 time, continuous gavage 7d, fasting 6h after last administration, docking is got blood and is surveyed mouse blood sugar level on an empty stomach.
Result:
2.1 mouse become mould situation
After administration 3d, weigh the body weight of all experiment mices, and the mode blood glucose meter adopting docking to get blood measures mouse tail vein blood glucose levels, measurement result shows, there are 47 mouse blood sugar concentration >11.0mmol/L, be diabetes model, different time is all dead after injection for other 13 mouse.There is obviously many foods, many drinks, diuresis and Body weight loss in the diabetic mice after Cheng Mo.
2.2 water extracts are on the impact of mouse blood sugar level
Successful for modeling 47 mouse are divided into 3 groups at random.Carry out gavage respectively as stated above, fasting 6h after last administration, docking is got blood and is surveyed mouse tail vein blood glucose levels.Measurement result shows, and after continuous water extract and melbine gavage, blood glucose in diabetic mice level obviously reduces, and model group mouse blood sugar level is higher.Result is as shown in table 1 below.
Table 1. medicine is on the impact of blood glucose in diabetic mice
Note: HI represents that blood sugar concentration is higher than 27.0mmol/L.
Experimental study shows, carry out gavage with tribute Chinese toon Herb Tea water extract, model mice blood sugar declines to some extent, although fall does not have chemical sugar-lowering medicine obvious, with control group significant difference.Although this illustrates that tribute Chinese toon Herb Tea of the present invention can not show maximum drug effect in a short time completely, slowly nurse one's health as a kind of tea-drinking, can play and progressively fall hypoglycemic effect.And, careless tea of the present invention drug products more in the market, have that toxic and side effect is little, taking convenience, can the advantage such as long-term taking.
The above, be only preferred embodiment of the present invention, not any formal and substantial restriction is done to the present invention, all those skilled in the art, do not departing within the scope of technical solution of the present invention, when utilizing disclosed above technology contents, and a little change made, modify with differentiation equivalent variations, be Equivalent embodiments of the present invention; Meanwhile, all above embodiment is done according to substantial technological of the present invention any change, modify and differentiation, all still belong in the scope of technical scheme of the present invention.
Claims (4)
1. there is a tribute Chinese toon Herb Tea for blood sugar reducing function, it is characterized in that, be made up of the raw material of following weight portion: Taihe county Chinese toon bud 1-4 part, tomorrow leaf 1-4 part, gynostemma pentaphyllum leaf 1-5 part.
2. tribute Chinese toon Herb Tea according to claim 1, is characterized in that, be made up of the raw material of following weight portion: Taihe county Chinese toon bud 1 part, tomorrow leaf 2 parts, gynostemma pentaphyllum leaf 1 part.
3. prepare a method for tribute Chinese toon Herb Tea as claimed in claim 1 or 2, it is characterized in that, comprise the following steps: Taihe county Chinese toon bud, plucked fresh Chinese toon bud before annual grain rains, pick decontamination, dry to moisture content and be less than 8.5%; Tomorrow leaf, picks clean leaf stalk, anthocaulus and spare impurity, dries to moisture content and is less than 8.5%; Gynostemma pentaphyllum leaf, after receiving, airing is less than 8.5% to moisture content, puts shady and cool airtight place preservation; The raw material of above-mentioned each weight portion is pulverized, crosses 40 order mesh screens, load pouch-packaged with the weight fraction of 3g after sterilization, namely obtain tribute Chinese toon Herb Tea.
4. prepare a method for the tea of tribute Chinese toon Herb Tea as claimed in claim 3, it is characterized in that, when drinking, get a small bag tea, brew 2 minutes with the 80-90 DEG C of boiling water of 200-300mL.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1283394A (en) * | 1999-08-06 | 2001-02-14 | 刘自福 | Chinese toon tea and preparing process thereof |
| CN1366831A (en) * | 2002-01-30 | 2002-09-04 | 刘志强 | Chinese toon tea and its preparation method |
| CN1397185A (en) * | 2001-07-18 | 2003-02-19 | 王珠山 | Gynostemma pentaphyllum tea and its prodn. method |
| CN102018066A (en) * | 2009-09-16 | 2011-04-20 | 郝敬方 | Composite cactus tea |
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2012
- 2012-09-03 CN CN201210321081.6A patent/CN103652105B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1283394A (en) * | 1999-08-06 | 2001-02-14 | 刘自福 | Chinese toon tea and preparing process thereof |
| CN1397185A (en) * | 2001-07-18 | 2003-02-19 | 王珠山 | Gynostemma pentaphyllum tea and its prodn. method |
| CN1366831A (en) * | 2002-01-30 | 2002-09-04 | 刘志强 | Chinese toon tea and its preparation method |
| CN102018066A (en) * | 2009-09-16 | 2011-04-20 | 郝敬方 | Composite cactus tea |
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| 已戊霖.明日叶香椿茶.《对症养生茶饮》.中国纺织出版社,2009,参见第201页右栏"明日叶香椿茶". * |
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