CN103638506B - 一种治疗痹症的中药 - Google Patents
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Abstract
本发明涉及一种治疗痹症的中药，它是由以下重量配比的原料药材制备而成：老鹳草5份、鹿骨8份、虎尾兰根2份、透骨香根4份、西藏桃叶珊瑚根5份、桧叶5份、漆大姑根2份、秦艽5份、二仙桃3份、蜂房3份、猫眼草2份、石蟹6份、檀香3份、茴香3份、丁香3份、没药4份、川牛漆3份、鬼箭羽3份、砂仁4份、苍术4份、石菖蒲4份、鹅不食草3份、细辛1份、侧柏叶4份、黄柏3份、莪术3份、干姜5份。临床实验证明，本发明能够安全有效治疗痹症。
Description
技术领域
本发明涉及一种中药，具体涉及一种治疗痹症的中药。
背景技术
痹症，是因风、寒、湿、热等外邪侵袭人体，闭阻经络而导致气血运行不畅的病证。主要表现为肌肉、筋骨、关节等部位酸痛或麻木、重着、屈伸不利，甚或关节肿大灼热等。目前痹症治疗主要是应用抗生素，疗效低，且副作用大。因此研究开发一种安全有效治疗痹症的中药非常有临床实用价值。
本发明中药所涉及药材的研究现状如下：
老鹳草: 本品为槐牛儿苗科植物牻牛儿苗或老鹳草、尼泊尔老鹳草、西伯利亚老鹤草及野老鹳草、块根者鹳草等带有果实的全草。【性味】味苦；微辛；性平。【归经】脾；膀胱经。【功能主治】祛风通络；活血；清热利湿。主风湿痹痛；肌肤麻木；筋骨酸楚；跌打损伤；泄泻痢疾；疮毒。【用法用量】9-15g。
鹿骨：为鹿科动物梅花鹿或马鹿的骨骼。【性味】味甘；性温。【归经】肾经。【功能主治】补虚赢；强筋骨；除风湿；止泻痢；生肌敛疮。主虚劳骨弱；风湿痹痛；泻痢；瘰疬；疮毒。【用法用量15-30g。
虎尾兰根：本品为龙舌兰科植物虎尾兰的根茎。【性味】辛；凉。【功能主治】怯风湿；通经络；活血消肿。主风湿关节痛；四肢麻木；跌打损伤。【用法用量】1-3g。
透骨香根:为杜鹃花科植物云南白珠树的根。【性味】辛，温。【功能主治】治胃寒痛，风湿筋骨疼痛，脚气，劳伤吐血，跌打损伤。【用法用量】1-3g。
西藏桃叶珊瑚根：为山茱萸科植物喜马拉雅珊瑚的根。【性味】味辛；苦；性温。【功能主治】祛风湿；通经络。主风湿骨痛；腰痛；跌打损伤。【用法用量】9-15g。
桧叶：为柏科植物圆柏的叶。【性味】辛；苦；性温；小毒。【功能主治】祛风散寒；活血解毒。主风寒感冒；风湿关节痛；荨麻疹；阴疽肿毒初起；尿路感染。【用法用量】15-30g。
漆大姑根：本品为大戟科植物毛果算盘子的根。【性味】味苦；涩；性平。【归经】大肠经。【功能主治】清热解毒；祛湿止痒。主肠炎；痢疾；牙痛；咽喉痛；乳腺炎；皮肤湿疹；烧伤；白带。【用法用量】15-60g。
秦艽：本品为龙胆科植物大叶龙胆、粗茎龙胆或西藏龙胆的根。【性味】苦；辛；微寒。【归经】胃；肝；胆经。【功能主治】祛风湿；舒筋络；清虚热；利湿退黄。主风湿痹通痛；筋骨拘挛；手足不遂；骨蒸潮热；小儿疳热；湿热黄疸。。
二仙桃：为兰科植物香花羊耳蒜的全草。【性味】味辛；苦；性温。【功能主治】解毒消肿；祛风除湿。主疮疡肿毒；风寒湿痹；白带；腰痛；咳嗽。【用法用量】6-15g。
蜂房：本品为胡蜂科昆虫果马蜂Polistes olivaceous （DeGeer）、日本长脚胡蜂Polistes japonicus Saussure 或异腹胡蜂Parapolybia varia Fabricius的巢。【性味】甘，平。【归经】归胃经。【功能主治】祛风，功毒，杀虫，止痛。用于龋齿牙痛，疮疡肿毒，乳痈，瘰疬，皮肤顽癣，鹅掌风。【用法用量】 3～5g。
猫眼草:本品为大戟科大戟属植物猫眼草Euphorbia lunulata Bunge的全草。性味】味苦；性微寒；有毒。【归经】肺；肝经。【功能主治】镇咳；祛痰；散结；逐水；拔毒；杀虫。主痰饮咳喘；水肿；瘰疬；疥癣；痹症。【用法用量】3-9g。
石蟹：本品为古生代节肢动物石蟹及其他近缘动物的化石。【性味】咸；寒；无毒。【归经】肝；胆；肾；胃；膀胱经。【功能主治】清热利湿；消肿解毒；去翳明目。主湿热淋浊；带下；喉痹；痈肿；漆疮；青盲；目赤；翳膜遮睛。【用法用量】内服：6-9g。
檀香：本品为檀香科檀香属植物檀香Santalum album L.树干的心材。【性味】辛，温。【归经】归脾、胃、心、肺经。【功能主治】行气温中，开胃止痛。用于寒凝气滞，胸痛，腹痛，胃痛食少；冠心病，心绞痛。【用法用量】 2～5g。
茴香：本品为伞形科植物茴香的果实。【性味】辛，温。【归经】入肾、膀胱、胃经。【功能主治】温肾散寒，和胃理气。治寒疝，少腹冷痛，肾虚腰痛，胃痛，呕吐，干、湿脚气。【用法用量】 2～5g。
丁香：本品为桃金娘科植物丁香Eugenia caryophllata Thunb.的干燥花蕾。【性味】辛，温。【归经】归脾、胃、肺、肾经。【功能主治】温中降逆，补肾助阳。用于脾胃虚寒，呃逆呕吐，食少吐泻，心腹冷痛，肾虚阳痿。【用法用量】 1～3g。
没药：本品为橄榄科植物没药树或爱伦堡没药树的胶树脂。【性味】苦；平。【归经】肝；脾；心；肾经。【功能主治】活血止痛；消肿生肌。主胸腹瘀痛；痛经；经闭；症瘕；跌打损伤；痈肿疮疡；肠痈；目赤肿痛。【用法用量】3-10g。
川牛漆：本品为苋科植物川牛膝Cyathula officinalis Kuan 的干燥根。【性味】甘、微苦，平。【归经】归肝、肾经。【功能主治】逐瘀通经，通利关节，利尿通淋。用于经闭症瘕，胞衣不下，关节痹痛，足痿筋挛，尿血血淋，跌扑损伤。【用法用量】 4.5～9g。
鬼箭羽：为卫矛科植物卫矛的具翅状物的枝条或翅状附属物。【性味】苦；辛；寒。【归经】肝经。【功能主治】破血通经；解毒消肿；杀虫。主症瘕结块；心腹疼痛；闭经；痛经；崩中漏下；产后瘀滞腹痛；恶露不下；疝气；历节痹痛；疮肿；跌打伤痛；虫积腹痛；烫火伤；毒蛇咬伤。【用法用量】4-9g。
砂仁：本品为姜科植物阳春砂或缩砂的成熟果实或种子。【性味】味辛；性温。【归经】脾；胃；肾经。【功能主治】化湿开胃；行气宽中温脾止泻安胎。主湿阻气滞；脘腹胀满；不思饮食；恶心呕吐；腹痛泄泻妊娠恶阻；胎动不安。【用法用量】3-6g。
苍术：本品为菊科植物南苍术或北苍术等的根茎。【性味】味辛；苦；性温。【归经】归脾；胃；肝经。【功能主治】燥湿健脾；祛风湿；明目。主湿困脾胃；倦怠嗜卧；胞痞腹胀；食欲不振；哎吐泄泻；痰饮；湿肿；表证夹湿；头身重痛；痹症温性；肢节酸痛重着；痿襞；夜盲。【用法用量】3-9g。
石菖蒲：本品为天南星科植物石菖蒲Acorus tatarinowii Schott 的干燥根茎。【性味】辛、苦，温。【归经】归心、胃经。【功能主治】化湿开胃，开窍豁痰，醒神益智。用于脘痞不饥，噤口下痢，神昏癫痫，健忘耳聋。【用法用量】 3～9g。
鹅不食草：本品为菊科植物鹅不食草 Centipeda minima （L.） A. Br. et Aschers. 的干燥全草。【性味】辛，温。【归经】归肺、肝经。【功能主治】通鼻窍，止咳，用于风寒头痛，咳嗽痰多，鼻塞不通，鼻渊流涕。【用法用量】 6～9g。
细辛：本品为马兜铃科植物辽细辛或华细辛的带根全草。【性味】辛，温。【归经】归心、肺、肾经。【功能主治】祛风散寒，通窍止痛，温肺化饮。用于风寒感冒，头痛，牙痛，鼻塞鼻渊，风湿痹痛，痰饮喘咳。【用法用量】 1～3g。
侧柏叶：为柏科植物侧柏的嫩枝与叶。【性味】苦；涩；性微寒。【归经】肺；肝；大肠经。【功能主治】凉血止血；止咳祛痰；祛风湿；散肿毒。主治咯血；吐血；衄血；尿血；血痢；肠风下血；崩漏不止；咳嗽痰多；风湿痹痛；丹毒；痄腮，烫伤。【用法用量】6-15g。
黄柏：本品为芸香科植物黄皮树Phellodendron chinense Schneid.或黄檗Phellodendron amurense Rupr.的干燥树皮。【性味】苦，寒。【归经】归肾、膀胱经。【功能主治】清热燥湿，泻火除蒸，解毒疗疮。用于湿热泻痢，黄疸，带下，热淋，痹症，痿{辟}，骨蒸劳热，盗汗，遗精，疮疡肿毒，湿疹瘙痒。盐黄柏滋阴降火。用于阴虚火旺，盗汗骨蒸。【用法用量】 3～12g.
莪术：本品为姜科植物莪术Curcuma aerugionosa Roxb.的根茎。【性味】味辛；苦；性温【归经】归肝、脾经。【功能主治】行气破血；消积止痛。主血气心痛；饮食积滞；脘腹胀痛；血滞经闭；痛经；症瘕瘤痞块；跌打损伤。【用法用量】3-10g。
干姜：本品为姜科植物姜Zingiber officinale Rosc.的干燥根茎。【性味】辛、热。【归经】归脾、胃、肾、心、肺经。【功能主治】干姜温中散寒，回阳通脉，燥湿消痰。用于脘腹冷痛，呕吐泄泻，肢冷脉微，痰饮喘咳。【用法用量】 3～9g。
发明内容
本发明旨在提供一种治疗痹症的中药，通过选择合适的药材及其配比，达到安全有效治愈痹症的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗痹症的中药，其特征在于，它是由以下重量配比的原料药材制备而成：老鹳草5份、鹿骨8份、虎尾兰根2份、 透骨香根4份、 西藏桃叶珊瑚根5份、桧叶5份、 漆大姑根2份、秦艽5份、二仙桃3份、 蜂房3份、猫眼草2份、石蟹6份、檀香3份、茴香3份、丁香3份、没药4份、川牛漆3份、鬼箭羽3份、砂仁4份、苍术4份、石菖蒲4份、鹅不食草3份、细辛1份、侧柏叶4份、黄柏3份、莪术3份、干姜5份。
下面结合中医理论说明本方明的有益效果：
发明人认为治疗痹症应从驱邪扶正固本、清热解毒、活血化瘀、祛风散结、散寒除湿、消炎止痛为主。本发明运用老鹳草、鹿骨、虎尾兰根、 透骨香根、 西藏桃叶珊瑚根、桧叶、 漆大姑根、秦艽、二仙桃、 蜂房、猫眼草、石蟹、檀香、茴香、丁香、没药、川牛漆、鬼箭羽、砂仁、苍术、石菖蒲、鹅不食草、细辛、侧柏叶、黄柏、莪术、干姜综合作用，能从根本上治疗痹症。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2009年1月-2013年4月间共收集50例痹症患者，年龄33-72岁，病程1-10年。随机分为：治疗组25例，对照组25例。两组性别、年龄等资料无显著性差异，具有可比性。
2、试验方法
2.1治疗方法
对照组口服三痹汤，每日一剂，疗程90天。
治疗组口服本发明按照具体实施例1制得的胶囊，每日2次。疗程90天。
2.2观察项目：实验前后，对疼痛，发麻、骨节大小血液生化指标化验记录。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状全部消失，试验室检查正常，半年内未见复发。好转：临床症状减轻，实验室检查改善或正常。无效：临床症状、实验室检查无明显好转或加重。
3.2治疗统计结果见表1。
表1 两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 不良反应例 | 总有效率(%) |
| 治疗组 | 25 | 5 | 14 | 6 | 2（8%） | 76% |
| 对照组 | 25 | 0 | 8 | 17 | 5（20%） | 32% |
可见，本发明制得的药物能够安全有效治疗痹症。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取老鹳草5g、鹿骨8g、虎尾兰根2g、 透骨香根4g、 西藏桃叶珊瑚根5g、桧叶5g、 漆大姑根2g、秦艽5g、二仙桃3g、 蜂房3g、猫眼草2g、石蟹6g、檀香3g、茴香3g、丁香3g、没药4g、川牛漆3g、鬼箭羽3g、砂仁4g、苍术4g、石菖蒲4g、鹅不食草3g、细辛1g、侧柏叶4g、黄柏3g、莪术3g、干姜5
g；加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人一天用量的胶囊剂。
用于治疗痹症。口服，每日分早晚两次服用。
具体实施例2
称取老鹳草5g、鹿骨8g、虎尾兰根2g、 透骨香根4g、 西藏桃叶珊瑚根5g、桧叶5g、 漆大姑根2g、秦艽5g、二仙桃3g、 蜂房3g、猫眼草2g、石蟹6g、檀香3g、茴香3g、丁香3g、没药4g、川牛漆3g、鬼箭羽3g、砂仁4g、苍术4g、石菖蒲4g、鹅不食草3g、细辛1g、侧柏叶4g、黄柏3g、莪术3g、干姜5g；加10倍量水，煎煮2小时，过滤；滤渣加8倍量水，煎煮1.5小时，过滤；合并滤液，浓缩，干燥，包装，即得符合正常成人一天用量的散剂。
用于治疗痹症。口服，每日一次。
具体实施例3
称取老鹳草5g、鹿骨8g、虎尾兰根2g、 透骨香根4g、 西藏桃叶珊瑚根5g、桧叶5g、 漆大姑根2g、秦艽5g、二仙桃3g、 蜂房3g、猫眼草2g、石蟹6g、檀香3g、茴香3g、丁香3g、没药4g、川牛漆3g、鬼箭羽3g、砂仁4g、苍术4g、石菖蒲4g、鹅不食草3g、细辛1g、侧柏叶4g、黄柏3g、莪术3g、干姜5g；加6倍量水，煎煮3次，每次煎煮1小时，合并煎煮液，浓缩，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即可制得符合正常成人一天用量的颗粒剂。
用于治疗痹症。口服，每日分早中晚三次服用。
Claims (1)
1.一种治疗痹症的中药，其特征在于，它是由以下重量配比的原料药材制备而成：老鹳草5份、鹿骨8份、虎尾兰根2份、 透骨香根4份、 西藏桃叶珊瑚根5份、桧叶5份、 漆大姑根2份、秦艽5份、二仙桃3份、 蜂房3份、猫眼草2份、石蟹6份、檀香3份、茴香3份、丁香3份、没药4份、川牛膝3份、鬼箭羽3份、砂仁4份、苍术4份、石菖蒲4份、鹅不食草3份、细辛1份、侧柏叶4份、黄柏3份、莪术3份、干姜5份。
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Effective date of registration: 20200821 Address after: Room 1303, unit 2, building 9, Tianhai yutianxia, 85 Tabei Road, Yuhua District, Shijiazhuang City, Hebei Province Patentee after: Jia Weiwei Address before: 233000 Room 1402, Ziyang Building, Pearl Plaza, Huaishang District, Bengbu City, Anhui Province Patentee before: Bengbu HRABERO Intellectual Property Service Co.,Ltd. |
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| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20151007 Termination date: 20211213 |