CN105497817A - 一种用于踝关节外伤后肿胀的中药制剂及其制备方法 - Google Patents
一种用于踝关节外伤后肿胀的中药制剂及其制备方法 Download PDFInfo
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Abstract
本发明公开了一种用于踝关节外伤后肿胀的中药制剂,它是由刘寄奴、血竭、补骨脂、淫羊藿、当归、白芍、桂枝、松节、骨碎补、细辛、草乌、川乌、皂角刺、桑枝、白芥子、泽泻、土鳖虫、柳枝、姜黄、独活、栀子、桃仁、红花、川芎、自然铜、伸筋草按照一定的重量配比制成,并将原料药水煎,浸泡患足,使之具有破瘀通经、止血消肿、补肾强骨的功效,其制备方法独特,治疗效果显著。
Description
技术领域
本发明涉及一种中药制剂,具体涉及一种用于踝关节外伤后肿胀的中药制剂,本发明还涉及该中药制剂的制备方法。
背景技术
踝关节外伤后肿胀是生活中的常见现象,生活中踝关节难免磕着碰着,轻者只会破皮流血,严重点的会引起肿胀,如果不及时治疗,还可能化脓感染,甚至可能引起发烧导致全身系统性损伤,给患者带来不小的痛苦。
目前一般对于踝关节外伤肿胀采用的治疗方法需要进行抗炎消肿止痛,西医一般会使用口服消炎药以及静脉滴注青霉素、阿奇霉素等消炎药物,这些消炎药不仅起效慢,而且全身用药副作用大,长期使用还会产生耐药性等缺点。一些地方主要也会采用局部用药,虽然可以直达病灶,但是常用的红药水、紫药水因含有重金属,反而容易导致中毒,常用的酒精具有易挥发性,杀菌作用有限,而且酒精并不具备消炎、止痛、活血的作用,因此目前临床上所使用的药物不能完全满足患者的要求。近年来,中医药治疗踝关节外伤肿胀有了很大发展,积累了许多经验。运用中医药调理病灶治疗疾病,具有明显的临床优势,且疗效肯定,不良反应小。
发明内容
本发明的目的在于提供一种用于踝关节外伤后肿胀的中药制剂,该中药制剂对于踝关节外伤后肿胀具有治疗效果好,价格低廉,无毒副作用,治愈时间短的特点。使患者早日摆脱病痛,恢复正常生活。
发明人在多年的临床医疗实践中,根据该病症的发展规律,以及中药的配伍原则,并通过大量的临床验证,反复探索总结出一种用于踝关节外伤后肿胀的中药制剂的新配方。本发明选择刘寄奴、血竭、补骨脂、淫羊藿、当归、白芍、桂枝、松节、骨碎补、细辛、草乌、川乌、皂角刺、桑枝、白芥子、泽泻、土鳖虫、柳枝、姜黄、独活、栀子、桃仁、红花、川芎、自然铜、伸筋草进行组合,药液泡足,使得各药物功效产生协同作用,使之具有破瘀通经、止血消肿、补肾强骨的功效,从而能够有效治疗踝关节外伤后肿胀。
本发明中药物的作用:
其中:
刘寄奴:为菊科植物奇蒿(HerbaArtemisiaeAnomalae)的带花全草。性味:味辛;微苦;性温。归心;肝;脾经。功效:破瘀通经;止血消肿;消食化积。用于经闭,痛经;产后瘀滞腹痛;恶露不尽,症瘕;跌打损伤;金疮出血;风湿痹痛;便血;尿血;痈疮肿毒;烫伤;食积腹痛;泄泻痢疾。
血竭:为棕榈科植物麒麟竭DaemonoropsdracoBlume.果实渗出的树脂经加工制成。性味:甘、咸,平。归心、肝经。功效:祛瘀定痛,止血生肌。用于跌扑折损,内伤瘀痛;外伤出血不止。《纲目》中记载:“骐驎竭,木之脂液,如人之膏血,其味甘咸而走血,盖手足厥阴药也。肝与心包皆主血故尔。河间刘氏云,血竭除血痛,为和血之圣药是矣。”。
补骨脂:为豆科植物补骨脂PsoraleacorylifoliaL.的果实。性味:辛、苦,温。归肾、脾经。功效:补肾壮阳,固精缩尿,温脾止泻,纳气平喘。本品能补肾阳、暖脾阳,止泄泻,为治脾肾阳虚之要药。本品辛苦温燥,能温补命门,补肾强腰,壮阳、固精、缩尿,为治肾阳不足、下元不固之要药。近代又研究出,补骨脂中的有效成分具有扩张血管的作用。
淫羊藿:为小檗科植物淫羊藿EpimediumbrevicornumMaxim.、箭叶淫羊藿Epimediumsagittatum(Sieb.etZucc.)Maxim.、柔毛淫羊藿EpimediumpubescensMaxim.、巫山淫羊藿EpimediumwushanenseT.S.Ying、或朝鲜淫羊藿EpimediumkoreanumNakai的干燥地上部分。性味:辛、甘,温。归肝、肾经。功效:补肾壮阳,祛风除湿。淫羊藿提取液具有雄性激素样作用,能提高机体免疫功能,特别是对肾虚病人免疫功能低下有改善作用;淫羊藿煎剂试管内对脊髓灰质炎病毒有显着的抑制作用,在药物与病毒接触1小时内,即表现灭活作用,对其他肠道病毒亦能抑制;对白色葡萄球菌、金黄色葡萄球菌有显着抑菌作用,对奈氏卡他球菌、肺炎双球菌、流感嗜血杆菌有轻度抑制作用。《本经》:主阴痿绝伤,茎中痛。利小便,益气力,强志。淫羊藿配伍桑寄生,对小儿麻痹症有一定的疗效。
当归:为伞形科植物当归Angelicasinensis(Oliv.)Diels的干燥根。性味:甘、辛、苦,温。归肝、心、脾经。功效:补血;活血;调经止痛;润燥滑肠。当归对中枢神经系统有抑制作用,挥发油有镇静、催眠、镇痛、麻醉等作用。用于血虚萎黄、眩晕心悸、虚寒腹痛、风湿痹痛、跌扑损伤、痈疽疮疡。据《本草正》载:“其味甘而重,故专能补血,其气轻而辛,故又能行血,能养营养血,补气生精,安五脏,强形体,益神志,凡有形虚损之病,无所不宜。”现代医学研究证实,当归具有抗菌、消炎作用,当归热水提取物对慢性风湿关节炎急性发作时有明显的抑制作用。当归能活血消肿止痛,又能补血生肌,故为外科多常用,常与红花等同用。
白芍:为双子叶植物毛茛科植物芍药PaeonialactifloraPall.的干燥根。性味:凉,苦酸,微寒。功效:补血柔肝、平肝止痛,敛阴收汗。研究表明:白芍中含有的芍药甙有抗菌、解热、抗炎、增加冠状动脉流量、改善心肌营养血流、扩张血管、对抗急性心肌缺血、抑制血小板聚集、镇静、镇痛、解痉、抗溃疡、调节血糖的作用。白芍煎剂能抑制痢疾杆菌、肺炎链球菌、大肠杆菌、伤寒杆菌、溶血性链球菌、绿脓杆菌等。本品能养肝血、敛肝阴、抑肝阳、疏肝气,又能缓挛急、止疼痛,为治疗肝经各种疼痛之良药。
桂枝:为樟科植物肉桂CinnamomumcassiaPresl的干燥嫩枝。性味:辛、甘,温。归心、肺、膀胱经。功效:发汗解肌,温通经脉,助阳化气,平冲降气。现代医学研究证实,桂枝能有效扩张血管、促进发汗,所含的桂皮醛、桂皮酸钠有解热、镇痛、镇静、抗惊厥作用,此外桂枝还有抗菌、抗病毒的功效。桂枝性温,善通阳气,能化阴寒,温通经络,用于寒凝血滞诸痛证。桂枝性温,善通阳气,能化阴寒,对阴寒遏阻阳气,津液不能输布,因而水湿停滞形成痰饮的病症。本品能温通经脉、散寒止痛,用于寒凝血滞等诸痛证。
松节:为松科植物油松PinustabulaeformisCarr、马尾松或云南松的枝干的结节。性味:苦,温。归心、肺经。功能主治:祛风除湿,活络止痛。用于风湿关节痛,腰腿痛,大骨节病,跌打肿痛。《本草汇言》:松节,气温性燥,如足膝筋骨,有风有湿,作痛作酸,痿弱无力者,用此立痊。倘阴虚髓乏,血燥有火者,宜斟酌用之。
骨碎补:为水龙骨科植物槲蕨Drynariafortunei(Kunze)J.Sm.的干燥根茎。全年均可采挖,除去泥沙,干燥,或再燎去茸毛(鳞片)。性味:苦,温。归肾、肝经。功效:补肾强骨,续伤止痛。用于肾虚腰痛,耳鸣耳聋,牙齿松动,跌扑闪挫,筋骨折伤;外治斑秃,白癜风。
细辛:为马兜铃科植物北细辛AsarumheterotropoidesFr.Schmidtvar.mandshuricum(Maxim.)Kitag.、汉城细辛AsarumsieboldiiMiq.var.seoulenseNakai或华细辛AsarumsieboldiiMiq.的干燥全草。性味:辛;温;小毒。归肺经、肾经、心经、肝经、胆经、脾经。功效:散结消肿;解表散寒;祛风止痛;温肺化饮;下气祛痰,通窍。抗菌、抗病毒作用细辛醇浸剂、挥发油等对革兰阳性菌、枯草杆菌和伤寒杆菌有一定的体外抑制作用,煎剂对结核杆菌和伤寒杆菌亦有抑制作用。细辛挥发油对多种真菌如黄曲霉菌、黑曲霉菌、白色念珠菌等均有抑制作用,抗菌的有效成分为黄樟醚。细辛辛香走窜,有较好的祛风寒,止疼痛的作用,用治风湿痹痛,腰膝酸冷,常配伍独活等药物。
草乌:为毛茛科植物北乌头AconitumkusnezoffiiReichb.的干燥块根。性味:辛、苦,热;有大毒。归心、肝、肾、脾经。功效:祛风除湿,温经止痛。用于风寒湿痹,关节疼痛,心腹冷痛,寒疝作痛,麻醉止痛。
川乌:为毛茛科植物乌头AconitumcarmichaeliDebx.的干燥母根。性味:辛、苦,热;有大毒。归心、肝、肾、脾经。功效:祛风除湿,温经止痛。用于风寒湿痹,关节疼痛,心腹冷痛,寒疝作痛,麻醉止痛。
皂角刺:为豆科植物皂荚GleditsiasinensisLam.的干燥棘刺。性味:辛,温。归肺、肝经。功效:消肿排脓,活血祛风。中医临床用于痈疽肿毒均有较好的治疗效果,一般表现为脓未成者可消,脓已成者可使之速溃。现代抗癌药理研究表明,皂角刺具有抗癌抑癌活性。现代药理学研究其煎剂用平板打洞法,对金黄色葡萄球菌和卡他球菌有抑制作用。皂角刺能引诸药上行,善治上焦之病。
桑枝:为桑科植物桑MorusalbaL.的干燥嫩枝。性味:微苦、平。归肝经。功效:祛风湿、利关节。用于风湿痹痛、四肢拘挛。
白芥子:十字花科一年或二年生植物白芥SinapisalbaL.的干燥成熟种子。性味:辛、温。归肺、胃经。功效:利气豁痰,温中散寒,通络止痛。治痰饮咳喘,胸胁胀满疼痛,反胃呕吐,中风不语,肢体痹痛麻木,脚气,阴疽,肿毒,跌打肿痛。
泽泻:为泽泻科植物泽泻Alismaorientalis(Sam.)Juzep.的干燥块茎。性味:甘、寒。归肾、膀胱经。功效:利小便,清湿热。用于水湿内停之水肿、小便不利。本品入肾、膀胱经,性寒善清下焦湿热。此外对金黄色葡萄球菌,肺炎双球菌,结核杆菌有抑制作用。本品入肾、膀胱经,性寒善清下焦湿热,多用于下焦湿热证。泽泻具有显著的利尿作用,能促进氯化物的排泄,增加尿量,对肾炎患者利尿作用更为明显,有降压、降血糖作用,还有抗脂肪肝的作用。
土鳖虫:为鳖蠊科昆虫地鳖EupolyphagasinensisWalker或冀地鳖Stelephagaplancyi(Boleny)的雌虫全体。性味:寒,咸;有小毒。归肝经。功效:破瘀血,续筋骨,用于治疗跌打损伤,筋伤骨折,瘀肿疼痛。本品咸寒入血,主入肝经,性善走窜,能活血消肿止痛,续筋接骨疗伤,为伤科常用药,尤多用于骨折筋伤,瘀血肿痛。
柳枝:为杨柳科植物垂柳的枝条。性味:苦,寒。入足阳明、厥阴经。功效:祛风,利尿,止痛,消肿。治风湿痹痛,淋病,白浊,小便不通,传染性肝炎,风肿,疔疮,丹毒,齿龋,龈肿。
姜黄:为姜科植物姜黄CurcumalongaL.的干燥根茎。性味:辛、苦,温。归脾、肝经。破血行气,通经止痛。用于胸胁剌痛,闭经,癓瘕,风湿肩臂疼痛,跌扑肿痛。姜黄和郁金配合使用善治臂背痛。
独活:为伞形科植物重齿毛当归AngelicapubescensMaxim.f.biserrataShanetYuan的干燥根。性味:辛、苦,微温。归肾、膀胱经。功效:祛风除湿,通痹止痛。用于风寒湿痹,腰膝疼痛,少阴伏风头痛。临床上常用于祛风胜湿,通痹止痛,凡风寒湿痹,关节疼痛,无论新久,均可应用,尤以下部之痹痛、腰膝酸痛、两足痿痹、屈伸不利等症为适宜。
栀子:为茜草科植物栀子GardeniajasminoidesEllis的干燥成熟果实。性味:苦,寒。归心、肺、三焦经。功效:泻火除烦,清热利尿,凉血解毒。用于热病心烦,黄疸尿赤,血淋涩痛,血热吐衄,目赤肿痛,火毒疮疡;外治扭挫伤痛。用生栀子研末,与面粉、黄酒调服,有消肿活络的作用,可用于跌仆损伤、扭挫伤、皮肤青肿疼痛等症。
桃仁:为蔷薇科植物桃Prunuspersica(L.)Batsch或山桃Prunusdavidiana(Carr.)Franch.的干燥成熟种子。性味:苦、甘,平。归心、肝、大肠经。功效:活血祛瘀,润肠通便,止咳平喘。桃仁祛瘀之力较强,又称破血药,用于治疗血瘀、癓瘕,常配红花、当归。桃仁对血流阻滞、血行障碍有改善作用,能使各脏器各组织机能恢复正常。
红花:为菊科植物红花CarthamustinctoriusL.的筒状花冠。性味:温,辛。归心、肝经。功效:活血通经、散瘀止痛。红花辛散温通,专入血分,能活血祛瘀,通经调脉,常与桃仁、当归、川芎等相须为用。红花有扩张血管作用。红花黄色素可明显延长血浆复钙时间、凝血酶原时间和凝血时间。
川芎:为伞形科植物川芎LigusticumchuanxiongHort.的干燥根茎。性味:辛,温。归肝、胆、心经。功效:活血行气,祛风止痛。本品辛散温通,能上行巅顶,下达血海,外彻皮毛,旁通四肢,既能活血又能行气,昔人谓川芎为血中之气药,殆言其寓辛散、解郁、通达、止痛等功能。川芎有明显的镇静作用。抗菌作用等体外试验:川芎对大肠、痢疾(宋内氏)、变形、绿脓、伤寒、副伤寒杆菌及霍乱弧菌等有抑制作用。
自然铜:为硫化物类矿物黄铁矿族黄铁矿。主含二硫化铁(FeS2)。性味:辛,平。归肝经。功效:散瘀,接骨,止痛。用于跌扑肿痛,筋骨折伤。主治一切恶疮及火烧烫伤。
伸筋草:为石松科石松属植物石松LycopodiumjaponicumThunb.的全草。性味:苦、辛、温。归肝经。功效:祛风除湿、舒筋活络。用于风寒湿痹,筋脉拘挛疼痈。外用治跌打扭伤肿痛。
本发明的方解是:方中刘寄奴破瘀通经、止血消肿,血竭祛瘀定痛、止血生肌,补骨脂、淫羊藿补肾壮阳,当归补血活血,以上五味共为君药,既可以补养身体之本,补肝肾以养筋骨,又可以从临床症状重散瘀止痛,止血消肿,缓解电解质不平衡导致的水肿现象,还可以补血活血,促进病灶的血液循环,从三个方面治疗缓解踝关节外伤后肿胀的症状。白芍补血柔肝,桂枝温经通脉,松节活络止痛,骨碎补增加君药补肾强骨、续伤止痛的效果,细辛消肿散结,草乌、川乌相须为用,可以温经止痛,皂角刺消肿排脓,以上八味共为臣药,臣药多数入肝经,古书中说,入肝家而行血分,定经络而达荣郁,可以使屈伸有利,加强血液循环,促进患处痊愈,同时还增加了君药的药效,加快患者的好转,桑枝祛风除湿,白芥子通络止痛,泽泻利尿清热,土鳖虫破瘀血,续筋骨,柳枝利尿止痛,姜黄通经止痛,独活通痹止痛,栀子凉血解毒,桃仁、红花活血祛瘀,川芎活血行气,自然铜散瘀止痛,伸筋草祛风除湿、舒筋活络,以上几味共为佐药,不仅可以增强君药治疗疾病的药效,还可以增加消肿止痛的作用,加快患者的好转,减轻患者的不适,加快患者的好转。此方诸药合用,君臣协力,佐使共辅,具有破瘀通经、止血消肿、补肾强骨的功效,能够有效治疗踝关节外伤后肿胀。
本发明药物原料用量是经发明人进行大量摸索总结得出的,各原料用量为在下述重量份范围都具有较好的疗效:刘寄奴25-35g、血竭3-9g、补骨脂15-25g、淫羊藿10-20g、当归13-23g、白芍10-20g、桂枝13-23g、松节7-17g、骨碎补15-25g、细辛3-9g、草乌4-14g、川乌4-14g、皂角刺15-25g、桑枝15-25g、白芥子4-14g、泽泻7-17g、土鳖虫5-15g、柳枝25-35g、姜黄7-17g、独活10-20g、栀子13-23g、桃仁7-17g、红花4-14g、川芎10-20g、自然铜15-25g、伸筋草13-23g。
其中优选为:刘寄奴30g、血竭6g、补骨脂20g、淫羊藿15g、当归18g、白芍15g、桂枝18g、松节12g、骨碎补20g、细辛6g、草乌9g、川乌9g、皂角刺20g、桑枝20g、白芥子9g、泽泻12g、土鳖虫10g、柳枝30g、姜黄12g、独活15g、栀子18g、桃仁12g、红花9g、川芎15g、自然铜20g、伸筋草18g。
一种用于踝关节外伤后肿胀的中药制剂的制备方法如下:
步骤一:按本发明重量配比,称取补骨脂、栀子、白芥子、桃仁用纱布包成药包,放于水中浸泡45分钟,过滤,备用;
步骤二:按本发明重量配比,称取血竭、松节、自然铜、土鳖虫粉碎研磨至120目筛,备用;
步骤三:按本发明重量配比,称取白芍、补骨脂、草乌、川乌、姜黄、独活、川芎放入砂锅中加步骤一中浸泡后剩余冷水,水量范围在5000-6000ml,用武火煎沸后,再用文火煎20~30分钟,过滤,得滤液,在剩余药渣中加入2000ml的水,加入刘寄奴、淫羊藿、当归、桂枝、细辛、皂角刺、桑枝、泽泻、柳枝、伸筋草以及步骤一中的药包,煎煮30分钟,最后加入红花煎煮10分钟,使得剩余药液在3000ml,过滤,弃渣,备用;
步骤四:将步骤三中的两次滤液合并,趁热加入步骤二中的粉末,搅拌均匀,既得本发明所述治疗踝关节外伤后肿胀的浸泡液。
本发明药物具有破瘀通经、止血消肿、补肾强骨的功效,且治疗效果好,价格低廉,无毒副作用,治愈时间短,该中药制剂采用的方式治疗可以减少西药对患者身体的伤害,减轻患者的病痛,据对临床150例患者观察统计,使用本发明药物一个疗程总有效率94%,两个疗程总有效率98%。
具体实施方式
实施例一、刘寄奴25g、血竭3g、补骨脂15g、淫羊藿10g、当归13g、白芍10g、桂枝13g、松节7g、骨碎补15g、细辛3g、草乌4g、川乌4g、皂角刺15g、桑枝15g、白芥子4g、泽泻7g、土鳖虫5g、柳枝25g、姜黄7g、独活10g、栀子13g、桃仁7g、红花4g、川芎10g、自然铜15g、伸筋草13g。
步骤一:按上述重量配比,称取补骨脂、栀子、白芥子、桃仁用纱布包成药包,放于水中浸泡45分钟,过滤,备用;
步骤二:按上述重量配比,称取血竭、松节、自然铜、土鳖虫粉碎研磨至120目筛,备用;
步骤三:按上述重量配比,称取白芍、补骨脂、草乌、川乌、姜黄、独活、川芎放入砂锅中加步骤一中浸泡后剩余冷水,水量范围在5000-6000ml,用武火煎沸后,再用文火煎20~30分钟,过滤,得滤液,在剩余药渣中加入2000ml的水,加入刘寄奴、淫羊藿、当归、桂枝、细辛、皂角刺、桑枝、泽泻、柳枝、伸筋草以及步骤一中的药包,煎煮30分钟,最后加入红花煎煮10分钟,使得剩余药液在3000ml,过滤,弃渣,备用;
步骤四:将步骤三中的两次滤液合并,趁热加入步骤二中的粉末,搅拌均匀,既得本发明所述治疗踝关节外伤后肿胀的浸泡液。
实施例二、刘寄奴30g、血竭6g、补骨脂20g、淫羊藿15g、当归18g、白芍15g、桂枝18g、松节12g、骨碎补20g、细辛6g、草乌9g、川乌9g、皂角刺20g、桑枝20g、白芥子9g、泽泻12g、土鳖虫10g、柳枝30g、姜黄12g、独活15g、栀子18g、桃仁12g、红花9g、川芎15g、自然铜20g、伸筋草18g。
制备和使用方法同实施例一。
实施例三、刘寄奴35g、血竭9g、补骨脂25g、淫羊藿20g、当归23g、白芍20g、桂枝23g、松节17g、骨碎补25g、细辛9g、草乌14g、川乌14g、皂角刺25g、桑枝25g、白芥子14g、泽泻17g、土鳖虫15g、柳枝35g、姜黄17g、独活20g、栀子23g、桃仁17g、红花14g、川芎20g、自然铜25g、伸筋草23g。
制备和使用方法同实施例一。
下面是患者使用本发明药物的临床统计资料:
一、一般资料
治疗踝关节外伤后肿胀患者300例。将患者随机分为观察组和对照组,其中男性158例,女性142例,男女比例1.1:1,最大年龄60岁,最小年龄7岁,病程时间不等,两组患者年龄、性别、病程等各项基本资料基本相同,差异无统计学意义(P>0.05)。
二、治疗方法:
1、按照本发明药物实施例二,以及所选的制备方法制备的制剂,一天一到两次,浸泡欢池,10日为一个疗程。
2、对照组按照常规治疗方法,采用内用消炎药加外涂具有杀菌消毒作用的紫药水,观察周期为10天。
三、疗效评定标准:
1、治愈:外伤患处红、肿、热、痛等症状完全消失,踝关节部位活动不受限制,皮肤恢复如初;
2、好转:外伤患处红。肿。热。痛等症状基本消失,踝关节可以稍加活动,皮肤略有青紫色;
3、未愈:踝关节肿胀、疼痛无任何改善。
四、观察组结果统计
对照组结果统计
其中:总有效率=治愈率+好转率
使用该中药制剂两个疗程两组患者的疗效对比情况
通过对比两组患者的治疗总有效率可以发现观察组明显高于对照组,由此说明,本发明中药在治疗踝关节外伤后肿胀具有良好的临床效果,能有效提高治疗的治愈率,值得在临床应用上推广。
典型病例及疗效:
病例一、患者齐某,男,12岁,喜欢轮滑运动,自己学习时,没有进行安全保护,摔倒在地,造成右脚踝关节处受伤,疼痛难忍,行动困难,经过拍片诊断,并未骨折,在社区医院治疗几天后,疼痛虽然减轻,但是瘀血肿胀并没有完全消失,回家静养,停药10天以后,还是行动不便,红肿并未消失,后开我处就诊,采用本发明实施例二中所制制剂,以及所选的制备方法,患者使用一个疗程后皮肤发红、肿胀现象逐渐好转,疼痛完全消失,又坚持使用了一个疗程,脚踝处活动自如,皮肤恢复正常,无任何不适现象,痊愈。
病例二、患者周某,男,59岁,失足在台阶上摔落,左腿踝关节处淤血红肿,疼痛难忍,并伴有高烧,医院进行拍片检查,发现并未伤到骨头,进行简单的伤口处理后,在社区医院进行治疗,高烧退去,但是患处改善的不明显,后来我处就诊,采用本发明实施例二中所制制剂,使用一个疗程后患者疼痛感消失,肿胀也慢慢减轻,可以下地走路,继续使用几天后,患者踝关节处屈伸有力,活动自如,疼痛感消失,皮肤恢复如初,痊愈。
Claims (4)
1.一种用于踝关节外伤后肿胀的中药制剂,其特征在于,该中药制剂是由以下重量份的药物制成:刘寄奴25-35g、血竭3-9g、补骨脂15-25g、淫羊藿10-20g、当归13-23g、白芍10-20g、桂枝13-23g、松节7-17g、骨碎补15-25g、细辛3-9g、草乌4-14g、川乌4-14g、皂角刺15-25g、桑枝15-25g、白芥子4-14g、泽泻7-17g、土鳖虫5-15g、柳枝25-35g、姜黄7-17g、独活10-20g、栀子13-23g、桃仁7-17g、红花4-14g、川芎10-20g、自然铜15-25g、伸筋草13-23g。
2.根据权利要求1所述的用于踝关节外伤后肿胀的中药制剂,其特征在于,由以下重量份的药物制成:刘寄奴30g、血竭6g、补骨脂20g、淫羊藿15g、当归18g、白芍15g、桂枝18g、松节12g、骨碎补20g、细辛6g、草乌9g、川乌9g、皂角刺20g、桑枝20g、白芥子9g、泽泻12g、土鳖虫10g、柳枝30g、姜黄12g、独活15g、栀子18g、桃仁12g、红花9g、川芎15g、自然铜20g、伸筋草18g。
3.根据权利要求1或2所述的用于踝关节外伤后肿胀的中药制剂,其特征在于:所述中药制剂为外用制剂。
4.一种用于踝关节外伤后肿胀的中药制剂的制备方法,其特征在于,制备方法如下:步骤一:按本发明重量配比,称取补骨脂、栀子、白芥子、桃仁用纱布包成药包,放于水中浸泡45分钟,过滤,备用;步骤二:按本发明重量配比,称取血竭、松节、自然铜、土鳖虫粉碎研磨至120目筛,备用;步骤三:按本发明重量配比,称取白芍、补骨脂、草乌、川乌、姜黄、独活、川芎放入砂锅中加步骤一中浸泡后剩余冷水,水量范围在5000-6000ml,用武火煎沸后,再用文火煎20~30分钟,过滤,得滤液,在剩余药渣中加入2000ml的水,加入刘寄奴、淫羊藿、当归、桂枝、细辛、皂角刺、桑枝、泽泻、柳枝、伸筋草以及步骤一中的药包,煎煮30分钟,最后加入红花煎煮10分钟,使得剩余药液在3000ml,过滤,弃渣,备用;步骤四:将步骤三中的两次滤液合并,趁热加入步骤二中的粉末,搅拌均匀,既得本发明所述治疗踝关节外伤后肿胀的浸泡液。
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