CN103638373B - Medicine used for treating angina pectoris, and preparation method thereof - Google Patents

Medicine used for treating angina pectoris, and preparation method thereof Download PDF

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CN103638373B
CN103638373B CN201310581893.9A CN201310581893A CN103638373B CN 103638373 B CN103638373 B CN 103638373B CN 201310581893 A CN201310581893 A CN 201310581893A CN 103638373 B CN103638373 B CN 103638373B
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蒋学
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Abstract

The invention discloses a medicine used for treating angina pectoris, and a preparation method thereof. The medicine is prepared from medical ingredients, such as citron, poria with hostwood, honey, cortex cinnamomi, angelica sinensis, rhizoma corydalis, ligusticum wallichii, fermented soybean, radix linderae, radix polygalae and fallopia japonica, according to a certain weight ratio. The medicine is capable of activating blood circulation and dispersing blood stasis, and relieving pain and regulating the flow of vital energy. Treatment effect on angina pectoris is realized quickly, treatment course is short, and angina pectoris is prevented from relapsing.

Description

One treats anginal medicine and preparation method thereof
Technical field
The present invention relates to one and treat anginal medicine and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Angina pectoris refers to because coronary atherosclerosis causes coronary insufficiency, and caused by myocardium ischemia and anoxia take precordialgia as one group of syndrome of main clinical manifestation.Angina pectoris at present at the sickness rate of China in ascendant trend year by year, the Health and Living of the people in serious harm.At present, western medicine angina pectoris poor effect, and long-term taking Western medicine has more side effect, therefore, there is very large demand to the anginal Chinese medicine of rapid, effective treatment in people.
Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and clinical test repeatedly and checking, finally have found the effectively anginal medicine for the treatment of, thus completes the present invention.
Object of the present invention is just to provide one can effectively treat anginal composition of medicine.
Another object of the present invention just there is provided the preparation method of this composition of medicine.
Medicine of the present invention selects Fructus Citri, Poria cum Radix Pini, Mel, Cortex Cinnamomi, Radix Angelicae Sinensis, Rhizoma Corydalis, Rhizoma Chuanxiong, Semen Sojae Preparatum, the Radix Linderae, Radix Polygalae, Rhizoma Polygoni Cuspidati, flower bud of Japanese apricot, Talcum, Herba Clematidis Huchouensis, Medulla Tetrapanacis, Semen Coicis, Arillus Longan, Radix Aconiti Lateralis Preparata, the Radix Astragali, Bulbus Allii Macrostemonis, Herba Leonuri, Flos Carthami, Lignum Sappan, Semen Trichosanthis, Herba Viciae Amoenae, Fructus Akebiae, Fructus Citri Sarcodactylis, Herba Aristolochiae, Pericarpium Arecae, Massa Medicata Fermentata medicine to combine, made by these drug regimens each efficacy of drugs produce synergism, thus can effectively treat anginal recurrence.Wherein select Fructus Citri to be because the arduous acid of its nature and flavor, temperature, enter liver, lung, spleen channel, regulate the flow of vital energy, Shu Yu, expectorant, the function of sharp diaphragm, treat for stomachache distension, and cough due to fluid-retention gas is stopped up, the few food of the sound of vomiting of vomitting.Poria cum Radix Pini is selected to be because its property slightly sweet flavor, flat, enter the heart, spleen channel, have mind calming, calm the nerves, the function of diuretic, control palpitation with fear of having a guilty conscience, forgetful, insomnia, frightened Epilepsy, dysuria.Select Mel to be that flat, enter lung, spleen, large intestine channel, have invigorating middle warmer, moisturize, pain relieving, the function of removing toxic substances, controls xeropulmonary cough, dryness of the intestine constipation, gastralgia, nasal sinusitis, aphtha, the burning hot wound of soup because its nature and flavor are sweet, separate Aconitum Carmichaeli.Select Cortex Cinnamomi to be because its property acrid-sweet flavor, heat, enters kidney, spleen, urinary bladder channel, has complement sun, warming the spleen and stomach, removing accumulated cold, the function of promoting blood circulation, controls decline of the fire from the gate of life, cold extremities faint pulse, and YANG-depletion is collapsed, and stomachache is had loose bowels, colic of cold type renal mass, chills and pain of the waist and kness, amenorrhea and mass in the abdomen, carbuncle of yin nature, multiple abscess, and empty sun is more floating, heat in the upper and cold in the lower.Select Radix Angelicae Sinensis to be because its nature and flavor sweet, acrid, warm, enter the heart, liver, spleen channel, have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize the function of laxation, control menoxenia, amenorrhea stomachache , mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood is dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty is just, heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Rhizoma Corydalis is selected to be that temperature, enter liver, stomach warp, invigorate blood circulation, dissipating blood stasis, regulates the flow of vital energy, the function of pain relieving, controls all pains of trusted subordinate's waist knee joint, menoxenia , mass in the abdomen, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury because its nature and flavor are worked hard.Select Rhizoma Chuanxiong to be that temperature, enters liver, gallbladder meridian, have activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness, the function of promoting blood circulation and stopping pain, control air-cooled headache and revolve dizzy because its nature and flavor are pungent, hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.Semen Sojae Preparatum is selected to be that cold, enter lung, stomach warp, have and induce sweat, relieving restlessness, Xuan Yu, the function of removing toxic substances, cure the wound cold and heat disease, cold and heat because its nature and flavor are bitter, headache, fidgety, uncomfortable in chest.Select the Radix Linderae to be that temperature, enters spleen, lung, kidney, urinary bladder channel, have pleasant, dissipating depression of QI, cold expelling, the function of pain relieving, control QI rising in reverse order chest and abdomen swelling and pain because its nature and flavor are pungent, dyspepsia is discontented with, and food is told in regurgitation, colic of cold type, beriberi, frequent micturition.Select Radix Polygalae to be because its nature and flavor toil, temperature, enter the heart, kidney channel, have Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm, the function of resolving depression, controls palpitation with fear, forgetful, nocturnal emission, insomnia, cough ant phlegm, and carbuncle skin ulcer swells.Select Rhizoma Polygoni Cuspidati to be because its nature and flavor are bitter, flat, dispel the wind, dampness removing, removing blood stasis with potent drugs, the function of stimulating the menstrual flow, dispelling the wind and dampness pathogens bones and muscles pain, jaundice due to damp-heat, stranguria with turbid discharge leukorrhagia, women's amenorrhea, lochiostasis , lumps in the chest and abdomen, anal fistula hematochezia, injury from falling down, scalds, malignant boil tinea disease.Select flower bud of Japanese apricot to be because the micro-acid of its nature and flavor, puckery, flat, return liver, stomach, lung meridian, have dissipating depression of QI and in, reduce phlegm, the function of removing toxic substances, controls gloomy vexed, stomachache due to hyperactive liver-QI attacking the stomach, and expectorant heat is stopped up stagnant, and inappetence, globus hystericus, scrofula is controlled in external, furuncle.Talcum is selected to be because its nature and flavor are sweet, light, cold, return bladder, lung, stomach warp, have inducing diuresis for treating stranguria syndrome, heat-clearing and toxic substances removing, the function of damp eliminating expelling summer-heat, control hematodiarrhoea, gonorrhea, urinate hot puckery pain, heat-damp in summer excessive thirst, damp and hot watery diarrhea, external treatment eczema, eczema, miliaria.Herba Clematidis Huchouensis is selected to be because it dispels the wind, the function of detumescence, treatment deep abscess, rheumatic arthritis, cerebroma.Medulla Tetrapanacis is selected to be that cool, enter lung, stomach warp, have eliminating the pathogens from the lung, diuresis, the function of lower milk, controls dysuria, gonorrhea, edema, puerpera's galactostasis, blurred vision because its property slightly sweet flavor, nasal obstruction.Semen Coicis is selected to be that cool, enter spleen, lung, kidney channel, have spleen invigorating, tonifying the lung, heat clearing away, the function of dampness removing, controls and have loose bowels, arthralgia chiefly caused by damp pathogen, the contracture of muscle arteries and veins, joint stuffiness, edema, beriberi, consumptive lung disease, lung abscess, acute appendicitis, stranguria with turbid discharge, leucorrhea because its property slightly sweet flavor.Select Arillus Longan to be because its nature and flavor are sweet, temperature, enter the heart, spleen channel, have heart-spleen boosting, fill blood, the function of calming the nerves, controls virtual work thin and weak, insomnia, forgetful, palpitation with fear, severe palpitation.Radix Aconiti Lateralis Preparata is selected to be because its property acrid-sweet flavor, heat, poisonous, enter the heart, spleen, kidney channel, have recuperating depleted YANG to mend fire, the function of dispelling cold and removing dampness, control excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhea is fainted inverse, trusted subordinate's cold type of pain, the splenic diarrhea cold-dysentery, beriberi edema, children's's intermittent infantile convulsion, the contracture of anemofrigid-damp arthralgia , Wei lame, the disease of the leakage of carbuncle of yin nature skin ulcer and all chronic diseaseses.Select the Radix Astragali to be that tepor, enters lung, spleen channel because its nature and flavor are sweet, life defends consolidating superficial resistance with useful, inducing diuresis to remove edema, poison holding, and the function of granulation promoting, controls spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, and carbuncle is not burst or burst and holds back for a long time; Processing the function with there being invigorating middle warmer benefit, controlling internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, the disease of metrorrhagia and leukorrhagia and all weakness of QI blood deficiency.Select Bulbus Allii Macrostemonis to be because its nature and flavor are worked hard, temperature, enter meridian of Hand-YANG MING, regulate the flow of vital energy, the chest stuffiness relieving, activate yang, the function of eliminating stagnation, control the thorough back of the body of obstruction of qi in the chest and cardialgia, gastral cavity painful abdominal mass is not relaxed, and retches, heavy after dysentery, furuncle.Select Herba Leonuri to be that cool, enter pericardium, Liver Channel, invigorate blood circulation, blood stasis dispelling, regulating menstruation, the function of the water that disappears, controls menoxenia because its nature and flavor are worked hard, control and Lou have difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, rushes down blood, carbuncle skin infection.Select Flos Carthami to be that temperature, enters the heart, Liver Channel, have promoting blood circulation to restore menstrual flow, the function of blood stasis removing pain relieving, control amenorrhea , mass in the abdomen because its nature and flavor are pungent, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis is had a pain, carbuncle, injury from falling down.Select Lignum Sappan to be because its nature and flavor are sweet, salty, flat, have promoting the circulation of blood, removing blood stasis with potent drugs, detumescence, the function of pain relieving, controls married woman's vim and vigour cardiac and abdominal pain, amenorrhea, postnatal blood stasis, distending pain dyspnea with rapid respiration, dysentery, tetanus.Semen Trichosanthis is selected to be because its nature and flavor are sweet, cold, return lung, stomach, large intestine channel, have moistening the lung and resolving phlegm, the function of laxation relieving constipation, control cough caused by dryness expectorant and stick, dryness of the intestine constipation.Select Herba Viciae Amoenae, call bean seedling, mountain Semen sojae atricolor, Herba speranskiae tuberculatae, be because its nature and flavor sweetness and bitterness, temperature, has wind-damp dispelling, invigorates blood circulation, relaxing muscles and tendons, the function of pain relieving, and dispelling the wind and dampness pathogens pain, sprain and contusion are hindered, innominate toxic swelling, eczema scrotum.Select Fructus Akebiae to be because its nature and flavor are sweet, cold, have liver-smoothing, qi-regulating, promoting blood circulation and stopping pain, the function of relieving restlessness diuresis, treating the liver peratodynia, gastric heat food is slow-witted, excessive thirst, dysentery, lumbago, hypochondriac pain, hernia, dysmenorrhea, and uterus drops.Selecting Fructus Citri Sarcodactylis, different name Fructus Citri Sarcodactylis, Bergamot, is that temperature, enter liver, stomach warp, regulate the flow of vital energy, the function of reducing phlegm, treats for stomachache, and coerces swollen, vomiting, dysphagic, phlegm retention cough with asthma, and can relieve the effect of alcohol because the arduous acid of its nature and flavor.Select Herba Aristolochiae to be because its nature and flavor are bitter, temperature, enter liver,spleen,kidney three warp, have circulation of qi promoting removing dampness, the function of promoting blood circulation and stopping pain, treats for stomachache, colicky, edema during pregnancy, and puerperal, vim and vigour were suffered from abdominal pain, rheumatalgia.Pericarpium Arecae is selected to be that tepor, enters spleen, stomach, intestine and small intestine warp, have therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, the function of row water, controls gastral cavity abdomen painful abdominal mass swollen, beriberi, edema because its nature and flavor are pungent.Select Massa Medicata Fermentata to be because its nature and flavor sweet, acrid, warm, enter upright stone tablet, stomach warp, have invigorating the spleen and regulating the stomach, the function helped digestion in adjusting, controls retention of food and drink, feeling of stuffiness in chest abdominal distention, vomiting dysentery, and postnatal blood stasis is suffered from abdominal pain, and children's's enlarged abdomen heavily fortified point is long-pending.
The drug dose of the present invention's combination is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight
Fructus Citri 15-25 gram of Poria cum Radix Pini 5-15 gram of Mel 5-15 gram
Cortex Cinnamomi 5-15 gram of Radix Angelicae Sinensis 15-25 gram of Rhizoma Corydalis 10-20 gram
Rhizoma Chuanxiong 5-15 gram of Semen Sojae Preparatum 15-25 gram of Radix Linderae 10-20 gram
Radix Polygalae 5-15 gram of Rhizoma Polygoni Cuspidati 15-25 gram of flower bud of Japanese apricot 10-20 gram
Talcum 5-15 gram of Herba Clematidis Huchouensis 15-25 gram of Medulla Tetrapanacis 10-20 gram
Semen Coicis 10-20 gram of Arillus Longan 10-20 gram of Radix Aconiti Lateralis Preparata 10-20 gram
Radix Astragali 10-20 gram of Bulbus Allii Macrostemonis 10-20 gram of Herba Leonuri 10-20 gram
Flos Carthami 5-15 gram of Lignum Sappan 15-25 gram of Semen Trichosanthis 15-25 gram
Herba Aristolochiae 5-15 gram of Fructus Akebiae 15-25 gram of Fructus Citri Sarcodactylis 15-25 gram
Herba Viciae Amoenae 5-15 gram of Pericarpium Arecae 15-25 gram of Massa Medicata Fermentata 15-25 gram
Preferable amount is
Fructus Citri 20 grams of Poria cum Radix Pinis 10 grams of Mel 10 grams
Cortex Cinnamomi 10 grams of Radix Angelicae Sinensis 20 grams of Rhizoma Corydalis 15 grams
Rhizoma Chuanxiong 10 grams of Semen Sojae Preparatums 20 grams of Radixs Linderae 15 grams
Radix Polygalae 10 grams of Rhizoma Polygoni Cuspidati 20 grams of flowers bud of Japanese apricot 15 grams
Talcum 10 grams of Herba Clematidis Huchouensiss 20 grams of Medulla Tetrapanaciss 15 grams
Semen Coicis 15 grams of Arillus Longans 15 grams of Radix Aconiti Lateralis Preparatas 15 grams
The Radix Astragali 15 grams of Bulbus Allii Macrostemonis 15 grams of Herba Leonuris 15 grams
Flos Carthami 10 grams of Lignum Sappans 20 grams of Semen Trichosanthis 20 grams
Herba Aristolochiae 10 grams of Fructus Akebiaes 20 grams of Fructus Citri Sarcodactyliss 20 grams
Herba Viciae Amoenae 10 grams of Pericarpium Arecae 20 grams of Massa Medicata Fermentata 20 grams
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Fructus Citri: get crude drug, removing impurity, wash quickly is clean, slightly moistens, shredding, cold drying, and sieve removes chip;
2, Poria cum Radix Pini: get crude drug, removing impurity, cleans, runs through, be cut into foursquare sheet or block, dry in the shade;
3, Mel: get pure Mel, temper with slow fire, filters skimming;
4, Cortex Cinnamomi: pick clean impurity, scrape off rough bark, the used time smashes, or scrapes off rough bark, infiltrates a moment by warm water, and section, dries;
5, Radix Angelicae Sinensis: pick decontamination, clean, moistening, when slightly drying in the air even to inside and outside humidity, section is dried;
6, Rhizoma Corydalis: pick decontamination, is soaked in water, and clean, solarization is dried in the air, and profit is even to inside and outside humidity, cuts into slices or smashes;
7, Rhizoma Chuanxiong: pick decontamination, separately large and small, be soaked in water, solarization is dried in the air, and cuts into slices after moistening, dry;
8, Semen Sojae Preparatum: original is used as medicine;
9, the Radix Linderae: pick decontamination, separately size bar, saturating with blister, changing water according to noting season, preventing smelly, pulling section out in time, sieve dedust bits;
10, Radix Polygalae: pick decontamination, cutting, sieve dedust bits;
11, Rhizoma Polygoni Cuspidati: adopt after, smooth file, dries;
12, flower bud of Japanese apricot: removing impurity, sieve dedust bits;
13, Talcum: get clean Talcum, break into coarse powder, water flies into superfine powder;
14, Herba Clematidis Huchouensis: summer, autumn adopt, using fresh herb;
15, Medulla Tetrapanacis: pick decontamination, section;
16, Semen Coicis: get crude drug, removing residual cot, impurity;
17, Arillus Longan: get crude drug, removing impurity;
18, Radix Aconiti Lateralis Preparata: be soaked in water, pulls out, and section, dries;
19, the Radix Astragali: pick clean impurity, the root head that removing is residual and hollow the greater, be soaked in water;
20, Bulbus Allii Macrostemonis: pick decontamination, sieve of winnowing with a dustpan goes whisker;
21, Herba Leonuri: pick decontamination, cleans, runs through, cutting, dry;
22, Flos Carthami: pick clean impurity, removing stem and leaf, base of a fruit head, dry;
23, Lignum Sappan: get crude drug, is sawn into short section, then is split into fragment or pound sheet;
24, Semen Trichosanthis: get crude drug, remove shrivelled seed, impurity, the used time smashs to pieces;
25, Herba Viciae Amoenae: pick decontamination, dries;
26, Fructus Akebiae: clean, slightly soak, moistening is to thoroughly, and section is dried, or cleans and dry, and the used time smashs to pieces;
27, Fructus Citri Sarcodactylis: pick decontamination, after water spray profit, chopping, dries;
28, Herba Aristolochiae: pick decontamination, clean earth, moistening, cutting is dried;
29, Pericarpium Arecae: pick clean impurity, rolloff makes soft, beats, sieve removes spare;
30, Massa Medicata Fermentata: get wheat bran and sprinkle evenly in hot pot, cigarette of having waited, pours into Massa Medicata Fermentata, fry to yellow, take out, sieve removes wheat bran, cools.
Two, prepare
1, the Fructus Citri of described weight, Poria cum Radix Pini, Mel, Cortex Cinnamomi, Radix Angelicae Sinensis, Rhizoma Corydalis, Rhizoma Chuanxiong, Semen Sojae Preparatum, the Radix Linderae, Radix Polygalae, Rhizoma Polygoni Cuspidati, flower bud of Japanese apricot, Talcum, Herba Clematidis Huchouensis, Medulla Tetrapanacis, Semen Coicis, Arillus Longan, Radix Aconiti Lateralis Preparata, the Radix Astragali, Bulbus Allii Macrostemonis, Herba Leonuri, Flos Carthami, Lignum Sappan, Semen Trichosanthis, Herba Viciae Amoenae, Fructus Akebiae, Fructus Citri Sarcodactylis, Herba Aristolochiae, Pericarpium Arecae, Massa Medicata Fermentata medicine were added 6 times amount water soakings after 150 minutes, intense fire decocts boiling 20 minutes, use slow fire boiling again 30 minutes, filter first time decoction liquor.
2, add water the medicinal residues of filtration 5 times amount, and intense fire decocts boiling, then uses slow fire boiling 30 minutes, filters to obtain second time decoction liquor.
3, by twice decoction liquor mixing, then the medicinal liquid that simmers in water 10 minutes to obtain, be divided into by medicinal liquid 6 doses to take.
Medicine of the present invention has invigorates blood circulation, and dissipating blood stasis, regulates the flow of vital energy, and effect of pain relieving, is used for the treatment of angina pectoris, short treating period, instant effect, non-relapse after healing, has no side effect.
Detailed description of the invention
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these test examples include animal toxicity test report and the clinical observation material of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention
Get rabbit 30, male and female dual-purpose, body weight 2.0-2.4kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, twice daily, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The anginal clinical observation material of [test example 2] Drug therapy of the present invention
1, physical data
Accept out-patient's totally 205 examples for medical treatment.
2, diagnostic criteria
Disease symptoms:
Angina pectoris with ictal chest pain for main clinical manifestation, pain., mainly in pareordia, there is hand size scope at position, and boundary is not bery clear.Often be radiated to inside left shoulder, left arm and reach the third finger and little finger of toe, neck, pharynx or lower jaw part also can occur sometimes uncomfortable; Chest pain is often compressing, stuffy or austerity, also can have burn feeling, but not sharp-pointed, and prick sample pain unlike acupuncture or cutter, during outbreak, patient often stops original activity unconsciously, until remission; Outbreak often by physical work or excited (as indignation, anxious, be overexcited) excite, be satiated with food, cold, smoking, tachycardia etc. also can bring out.Typical angina pectoris is normal under similar conditions, and morning is multiple; Pain can be alleviated after generally continuing 3 ~ 5 clocks gradually, and sublingual administration nitroglycerin also can make it to alleviate within a few minutes.Can a couple of days or a few weeks longer outbreak once, also can show effect repeatedly in one day.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, each serving with 1 dose, every day is early, middle and late respectively takes 1 time, within 7 days, is a course for the treatment of, takes 7 courses for the treatment of continuously.
4, efficacy assessment standard
Effective: angina pectoris symptom disappears, body constitution recovers normal, observes half a year without recidivist;
Take a turn for the better: angina pectoris symptom is clearly better, and body constitution is progressively recovered;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
In above-mentioned treatment, by Drug therapy patient with angina pectoris 205 example of the present invention, effective 195 examples of result, obvious effective rate is 95.12%, and take a turn for the better 7 examples, and improvement rate is 3.42%, and invalid 3 examples, total effective rate is 98.54%.

Claims (3)

1. treat an anginal medicine, it is characterized in that: it is made up of the crude drug in following weight range:
Fructus Citri 15-25 gram of Poria cum Radix Pini 5-15 gram of Mel 5-15 gram
Cortex Cinnamomi 5-15 gram of Radix Angelicae Sinensis 15-25 gram of Rhizoma Corydalis 10-20 gram
Rhizoma Chuanxiong 5-15 gram of Semen Sojae Preparatum 15-25 gram of Radix Linderae 10-20 gram
Radix Polygalae 5-15 gram of Rhizoma Polygoni Cuspidati 15-25 gram of flower bud of Japanese apricot 10-20 gram
Talcum 5-15 gram of Herba Clematidis Huchouensis 15-25 gram of Medulla Tetrapanacis 10-20 gram
Semen Coicis 10-20 gram of Arillus Longan 10-20 gram of Radix Aconiti Lateralis Preparata 10-20 gram
Radix Astragali 10-20 gram of Bulbus Allii Macrostemonis 10-20 gram of Herba Leonuri 10-20 gram
Flos Carthami 5-15 gram of Lignum Sappan 15-25 gram of Semen Trichosanthis 15-25 gram
Herba Aristolochiae 5-15 gram of Fructus Akebiae 15-25 gram of Fructus Citri Sarcodactylis 15-25 gram
Herba Viciae Amoenae 5-15 gram of Pericarpium Arecae 15-25 gram of Massa Medicata Fermentata 15-25 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Fructus Citri 20 grams of Poria cum Radix Pinis 10 grams of Mel 10 grams
Cortex Cinnamomi 10 grams of Radix Angelicae Sinensis 20 grams of Rhizoma Corydalis 15 grams
Rhizoma Chuanxiong 10 grams of Semen Sojae Preparatums 20 grams of Radixs Linderae 15 grams
Radix Polygalae 10 grams of Rhizoma Polygoni Cuspidati 20 grams of flowers bud of Japanese apricot 15 grams
Talcum 10 grams of Herba Clematidis Huchouensiss 20 grams of Medulla Tetrapanaciss 15 grams
Semen Coicis 15 grams of Arillus Longans 15 grams of Radix Aconiti Lateralis Preparatas 15 grams
The Radix Astragali 15 grams of Bulbus Allii Macrostemonis 15 grams of Herba Leonuris 15 grams
Flos Carthami 10 grams of Lignum Sappans 20 grams of Semen Trichosanthis 20 grams
Herba Aristolochiae 10 grams of Fructus Akebiaes 20 grams of Fructus Citri Sarcodactyliss 20 grams
Herba Viciae Amoenae 10 grams of Pericarpium Arecae 20 grams of Massa Medicata Fermentata 20 grams.
3. the preparation method of medicine according to claim 1 or 2, is characterized in that: it comprises the following steps:
(1) get the raw materials ready
(1) Fructus Citri: get crude drug, removing impurity, wash quickly is clean, slightly moistens, shredding, cold drying, and sieve removes chip;
(2) Poria cum Radix Pini: get crude drug, removing impurity, cleans, runs through, be cut into foursquare sheet or block, dry in the shade;
(3) Mel: get pure Mel, temper with slow fire, filters skimming;
(4) Cortex Cinnamomi: pick clean impurity, scrape off rough bark, the used time smashes, or scrapes off rough bark, infiltrates a moment by warm water, and section, dries;
(5) Radix Angelicae Sinensis: pick decontamination, clean, moistening, when slightly drying in the air even to inside and outside humidity, section is dried;
(6) Rhizoma Corydalis: pick decontamination, is soaked in water, and clean, solarization is dried in the air, and profit is even to inside and outside humidity, cuts into slices or smashes;
(7) Rhizoma Chuanxiong: pick decontamination, separately large and small, be soaked in water, solarization is dried in the air, and cuts into slices after moistening, dry;
(8) Semen Sojae Preparatum: original is used as medicine;
(9) Radix Linderae: pick decontamination, separately size bar, saturating with blister, changing water according to noting season, preventing smelly, pulling section out in time, sieve dedust bits;
(10) Radix Polygalae: pick decontamination, cutting, sieve dedust bits;
(11) Rhizoma Polygoni Cuspidati: adopt after, smooth file, dries;
(12) flower bud of Japanese apricot: removing impurity, sieve dedust bits;
(13) Talcum: get clean Talcum, break into coarse powder, water flies into superfine powder;
(14) Herba Clematidis Huchouensis: summer, autumn adopt, using fresh herb;
(15) Medulla Tetrapanacis: pick decontamination, section;
(16) Semen Coicis: get crude drug, removing residual cot, impurity;
(17) Arillus Longan: get crude drug, removing impurity;
(18) Radix Aconiti Lateralis Preparata: be soaked in water, pulls out, and section, dries;
(19) Radix Astragali: pick clean impurity, the root head that removing is residual and hollow the greater, be soaked in water;
(20) Bulbus Allii Macrostemonis: pick decontamination, sieve of winnowing with a dustpan goes whisker;
(21) Herba Leonuri: pick decontamination, cleans, runs through, cutting, dry;
(22) Flos Carthami: pick clean impurity, removing stem and leaf, base of a fruit head, dry;
(23) Lignum Sappan: get crude drug, is sawn into short section, then is split into fragment or pound sheet;
(24) Semen Trichosanthis: get crude drug, remove shrivelled seed, impurity, the used time smashs to pieces;
(25) Herba Viciae Amoenae: pick decontamination, dries;
(26) Fructus Akebiae: clean, slightly soak, moistening is to thoroughly, and section is dried, or cleans and dry, and the used time smashs to pieces;
(27) Fructus Citri Sarcodactylis: pick decontamination, after water spray profit, chopping, dries;
(28) Herba Aristolochiae: pick decontamination, clean earth, moistening, cutting is dried;
(29) Pericarpium Arecae: pick clean impurity, rolloff makes soft, beats, sieve removes spare;
(30) Massa Medicata Fermentata: get wheat bran and sprinkle evenly in hot pot, cigarette of having waited, pours into Massa Medicata Fermentata, fry to yellow, take out, sieve removes wheat bran, cools;
(2) prepare
(1) Fructus Citri of described weight, Poria cum Radix Pini, Mel, Cortex Cinnamomi, Radix Angelicae Sinensis, Rhizoma Corydalis, Rhizoma Chuanxiong, Semen Sojae Preparatum, the Radix Linderae, Radix Polygalae, Rhizoma Polygoni Cuspidati, flower bud of Japanese apricot, Talcum, Herba Clematidis Huchouensis, Medulla Tetrapanacis, Semen Coicis, Arillus Longan, Radix Aconiti Lateralis Preparata, the Radix Astragali, Bulbus Allii Macrostemonis, Herba Leonuri, Flos Carthami, Lignum Sappan, Semen Trichosanthis, Herba Viciae Amoenae, Fructus Akebiae, Fructus Citri Sarcodactylis, Herba Aristolochiae, Pericarpium Arecae, Massa Medicata Fermentata medicine were added 6 times amount water soakings after 150 minutes, intense fire decocts boiling 20 minutes, use slow fire boiling again 30 minutes, filter first time decoction liquor;
(2) add water the medicinal residues of filtration 5 times amount, and intense fire decocts boiling, then uses slow fire boiling 30 minutes, filters to obtain second time decoction liquor;
(3) by twice decoction liquor mixing, then the medicinal liquid that simmers in water 10 minutes to obtain, be divided into by medicinal liquid 6 doses to take.
CN201310581893.9A 2013-11-20 2013-11-20 Medicine used for treating angina pectoris, and preparation method thereof Expired - Fee Related CN103638373B (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1115658A (en) * 1994-09-16 1996-01-31 韩瑞文 Chinese medicine composite for coronary heart disease and angina

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1115658A (en) * 1994-09-16 1996-01-31 韩瑞文 Chinese medicine composite for coronary heart disease and angina

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