CN103585535B - 一种治疗扁平疣的中药 - Google Patents
一种治疗扁平疣的中药 Download PDFInfo
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Abstract
本发明涉及一种治疗扁平疣的中药，由以下重量配比的药材制备而成：扶桑金星蕨12份、禾叶毛兰14份、枫香脂10份、飞廉12份、凤凰木14份、分枝火绒草14份、肥肉草16份、地桃花8份、蝶毛菌12份、二叶舞鹤草18份、姜三七12份、粉防己14份、红活麻15份、法罗海16份、大细辛12份、多穗石柯叶8份、梵天花15份。临床实验证明，本发明能够安全有效治疗扁平疣。
Description
技术领域
本发明涉及一种中药，具体涉及一种治疗扁平疣的中药。
背景技术
扁平疣是由人乳头状瘤病毒（HPV）感染引起的，好发于青少年的病毒感染性疾病。临床表现为皮色或粉红色的扁平丘疹，多见于面部和手背，无明显的自觉症状，病程慢性。可通过直接或间接的接触传染。表现为大小不等的扁平丘疹，轻度隆起，表面光滑，呈圆形、椭圆形或多角形，境界清楚，可密集分布或由于局部搔抓而呈线状排列，一般无自觉症状，部分患者自觉轻微瘙痒。病理检查表皮网篮状角化过度伴角化不全，棘层肥厚，表皮上部可见较多空泡细胞，胞核嗜碱，颗粒层均匀肥厚。真皮改变不明显。
对于扁平疣目前尚缺少公认安全有效的治疗药物。
本发明中药所涉及药材的研究现状如下：
扶桑金星蕨【来源】为金星蕨科植物中日金星蕨的全草。夏、秋季采收，洗净，鲜用或晒干。【功能主治】止血消炎。主外伤出血。
禾叶毛兰【来源】兰科毛兰属植物禾叶毛兰Eria graminifolia Lindl.，以全草入药。7～8月采集，洗净切段晒干。【功能主治】益胃，生津。用于热病伤津，口干烦渴，病后虚热，胃酸缺乏。
枫香脂【来源】本品为金缕梅科植物枫香树Liquidambar formosana Hance 的干燥树脂。7 、8 月间割裂树干，使树脂流出，10月至次年4月采收，阴干。【功能主治】活血止痛，解毒，生肌，凉血。用于跌扑损伤，痈疽肿痛，吐血，衄血，外伤出血。
飞廉【来源】为菊科植物丝毛飞廉与节毛飞廉的全草或根。春、夏季采收全草及花，秋季挖根，鲜用或除花阴干外，其余切段晒干。【功能主治】祛风；清热；利湿；凉血止血；活血消肿。主感冒咳嗽；头痛眩晕；泌尿系感染；乳糜尿；白带；黄疸；风湿痹痛；吐血；衄血；尿血；月经过多。
凤凰木【来源】为豆科植物凤凰木的树皮。夏、秋季采收为好，剥取树皮，切段晒干。【功能主治】平肝潜阳。主肝热型高血压，眩晕，心烦不宁。
分枝火绒草【来源】为菊科植的戟叶火绒草的全草。6-7月采收，去根，洗净，晾干。【功能主治】祛寒止痛。主胃寒；腹痛；风湿关节疼痛。
肥肉草【来源】为野牡丹科植物肥肉草的全草。夏、秋季采收，晒干或鲜用。【功能主治】清热利湿；凉血消肿。主痢疾；腹泻；吐血；痔血。
地桃花【来源】为锦葵科植物地桃花或粗叶地桃花的根或全草。全年均可采，洗净，鲜用或晒干。【功能主治】祛风利湿；活血消种；消热解毒。主感冒；风湿痹痛；痢疾；泄泻；淋证；带下；月经不调；跌打肿痛；喉痹；乳痈；疮疖；毒蛇咬伤。
蝶毛菌【来源】为多孔菌科真菌毛革盖菌的子实体。【功能主治】祛风除湿；清肺止咳；祛腐生肌。主风湿疼痛；肺热咳嗽；疮疡脓肿。
二叶舞鹤草【来源】为百合科植物二叶舞鹤草的全草。7-8月采收壤洗净，晒干或鲜用。【功能主治】凉血止血；清热解毒。主吐血；尿血；月经过多；外伤出血；疮痈肿痛。
姜三七【来源】姜科姜七属植物姜三七Stahlianthus involucratus （King） Craib，以根状茎入药。全年可采，洗净晒干。【功能主治】活血散瘀，消肿止痛。用于跌打损伤，风湿骨痛，吐血衄血，月经过多；外用治虫蛇咬伤，外伤出血。
粉防己【来源】为防己科植物石蟾蜍Stephania tetrandra S. Moore的根。秋季采挖，除去粗皮，晒至半干，切段或纵剖，干燥。【功能主治】利水消肿，祛风止痛。用于水肿脚气、小便不利、风湿痹痛、湿疹疮毒、高血压症。
红活麻【来源】荨麻科蝎子草属植物掌叶蝎子草Girardiana heterophylla Decne.和荨麻属植物湖北红活麻Urtica dentata Hand.-Mazz.，以全草入药。夏秋采集，晒干。【功能主治】祛风除湿，利湿消肿。用于风湿关节痛，跌打损伤，水肿。
法罗海【来源】为伞形科植物阿坝当归的根。秋末、冬妆叶枯萎时采收，挖取根部，除去茎叶或保留长约1cm的叶鞘残基，去净泥土，干燥。【功能主治】理气止痛；止咳平喘。主胸胁脘腹疼痛；头痛；咳喘。
大细辛【来源】为马兜铃科植物大叶马蹄香、祁阳细辛和鼎湖细辛的带根全草。春、夏采收，洗净，晒干。广西则在冬季挖取全株，洗净，风干。【功能主治】祛风散寒；止咳祛痰；活血解毒；止痛。主风寒感冒；咳喘；牙痛；中暑腹痛；肠炎；痢疾；风湿关节疼痛；跌打损伤；痈疮肿毒；蛇咬伤。
多穗石柯叶【来源】为壳斗科植物多穗石.的叶。春、夏、秋季摘叶，晒干或鲜用。【功能主治】清热解毒；化痰；祛风；降压。主湿热泻痢；肺热咳嗽；痈疽疮疡；皮肤瘙痒；高血压。
梵天花【来源】为锦葵科植物梵天花的全草。夏、秋季采挖全草，洗净，除去杂质，切碎，晒干。【功能主治】祛风利湿；消热解毒。主风湿痹痛；泄泻；痢疾；感冒；咽喉肿痛；肺热咳嗽；风毒流注；疮疡肿毒；跌打损伤；毒蛇咬伤。
发明内容
本发明旨在提供一种治疗扁平疣的中药，通过选择合适的药材及其配比，达到安全有效治愈扁平疣的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗扁平疣的中药，其特征在于，由以下重量配比的药材制备而成：扶桑金星蕨12份、禾叶毛兰14份、枫香脂10份、飞廉12份、凤凰木14份、分枝火绒草14份、肥肉草16份、地桃花8份、蝶毛菌12份、二叶舞鹤草18份、姜三七12份、粉防己14份、红活麻15份、法罗海16份、大细辛12份、多穗石柯叶8份、梵天花15份。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2010年12月-2013年1月间共收集116例扁平疣的门诊患者，年龄28-61岁，病程1-5年。随机分为：治疗组92例，空白组24例。两组年龄、病情等资料无显著性差异，具有可比性。
2、试验方法
2.1治疗组口服本发明按照具体实施例1制得的胶囊，早晚各一次。疗程30天。
2.2空白组口服安慰剂胶囊，早晚各一次。疗程30天。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状全部消失，试验室检查正常，愈后观察三个月未见复发。好转：临床症状减轻，病情得到控制，实验室检查改善或正常。无效：临床症状无明显好转或加重。
3.2治疗统计结果见表1。
表1 两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 总有效率(%) | 不良反应例 |
| 治疗组 | 92 | 32（34.8%） | 50（54.3%) | 10（10.9%) | 89.1% | 0 |
| 空白组 | 24 | 0 | 5（20.8%） | 19（79.2%） | 20.8% | 0 |
可见，本发明制得的药物能够安全有效治疗扁平疣。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取：扶桑金星蕨12克、禾叶毛兰14克、枫香脂10克、飞廉12克、凤凰木14克、分枝火绒草14克、肥肉草16克、地桃花8克、蝶毛菌12克、二叶舞鹤草18克、姜三七12克、粉防己14克、红活麻15克、法罗海16克、大细辛12克、多穗石柯叶8克、梵天花15克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
用于治疗扁平疣。口服，每日分早晚两次服用。
具体实施例2
称取：扶桑金星蕨12克、禾叶毛兰14克、枫香脂10克、飞廉12克、凤凰木14克、分枝火绒草14克、肥肉草16克、地桃花8克、蝶毛菌12克、二叶舞鹤草18克、姜三七12克、粉防己14克、红活麻15克、法罗海16克、大细辛12克、多穗石柯叶8克、梵天花15克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，粉碎，即得符合正常成人1天用量的散剂。
用于治疗扁平疣。口服，每日分早晚两次服用。
具体实施例3
称取：扶桑金星蕨12克、禾叶毛兰14克、枫香脂10克、飞廉12克、凤凰木14克、分枝火绒草14克、肥肉草16克、地桃花8克、蝶毛菌12克、二叶舞鹤草18克、姜三七12克、粉防己14克、红活麻15克、法罗海16克、大细辛12克、多穗石柯叶8克、梵天花15克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即可制得符合正常成人1天用量的颗粒剂。
用于治疗扁平疣。口服，每日分早晚两次服用。
Claims (1)
1.一种治疗扁平疣的中药，其特征在于，由以下重量配比的药材制备而成：扶桑金星蕨12份、禾叶毛兰14份、枫香脂10份、飞廉12份、凤凰木14份、分枝火绒草14份、肥肉草16份、地桃花8份、蝶毛菌12份、二叶舞鹤草18份、姜三七12份、粉防己14份、红活麻15份、法罗海16份、大细辛12份、多穗石柯叶8份、梵天花15份。
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