CN103690613B - 一种治疗伪膜性肠炎的中药 - Google Patents
一种治疗伪膜性肠炎的中药 Download PDFInfo
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Abstract
本发明涉及一种治疗伪膜性肠炎的中药，由以下重量配比的药材制备而成：白叶火草8份、千屈草12份、午时花14份、泥胡菜10份、白龙穿彩12份、芦子兰14份、三筒管15份、布朗耳蕨10份、实葫芦12份、半边旗10份、北鹤虱8份、矮醋栗8份、八角枫花12份、伯乐树10份、矮脚南9份、阿里红12份、凹头苋10份、小叶黑面叶14份。临床实验证明，本发明能够安全有效治疗伪膜性肠炎。
Description
技术领域
本发明涉及一种中药，具体涉及一种治疗伪膜性肠炎的中药。
背景技术
伪膜性肠炎是一种主要发生于结肠和小肠的急性纤维素渗出性炎症，多发生于老年人、重症患者、免疫功能低下及外科大手术后的患者，其临床表现轻重不一，可仅为轻度腹泻，也可出现高热、严重腹泻、水电解质紊乱、中毒性巨结肠，甚至危及生命。该病病情重，治疗不及时病死率高。
对于伪膜性肠炎目前尚缺少公认安全有效的治疗药物。
本发明中药所涉及药材的研究现状如下：
白叶火草【来源】为菊科植物植物白千里光的根或全草。夏、秋季采收，洗净，晒干。【功能主治】散风热；定喘咳；利水湿。主感冒发热；咳喘；小便淋涩；肾炎水肿。
千屈菜【来源】为千屈菜科千屈菜属植物千屈菜Lythrum salicaria L.，以全草入药。夏秋采集，除去泥沙，晒干或鲜用。【功能主治】清热解毒，凉血止血。用于肠炎，痢疾，便血；外用治外伤出血。
午时花【来源】马齿苋科马齿苋属植物大花马齿苋Portulaca grandiflora Hook.，以地上全草入药。四季可采，一般鲜用，或晒干。【功能主治】散瘀止痛，解毒消肿。用于跌打损伤；外用治疮疖肿毒。
泥胡菜【来源】菊科泥胡菜属植物泥胡菜Hemistepta lyrata Bunge，以全草入药。四季可采，洗净，鲜用或晒干扎捆，用时切段。【功能主治】消肿散结，清热解毒。用于乳腺炎，颈淋巴结炎，痈肿疔疮，风疹瘙痒。
白龙穿彩【来源】唇形科盘泽草属植物白龙穿彩Panzeria alashanica Kupr.，以全草入药。夏季花未开或初开时割取全草，晒干。【功能主治】调经活血，清热利水。用于产后腹痛，月经不调，急性肾炎，子宫出血，乳腺炎，丹毒，疖肿。
芦子兰【来源】胡椒科胡椒属植物荨麻叶胡椒Piper boehmeriaefolium Wall.，以全株入药。全年可采，切片晒干。【功能主治】祛风散寒，理气止痛。用于感冒，胃痛，痛经，跌打损伤，风湿骨痛。
白金古榄【来源】为马兜铃科马兜铃属植物白金古榄Aristolochia championii Merr.etChun.，以块根入药。秋季采，洗净切片，晒干备用。【功能主治】清热解毒。用于急性肠胃炎，细菌性痢疾，疮疖肿毒。
布朗耳蕨【来源】为鳞毛蕨种植物布朗耳蕨的全草。8～9月采挖，切段，晒干。【功能主治】清热解毒。治病毒发疹。
实葫芦【来源】葫芦科栝楼属植物喜马拉雅瓜蒌Trichosanthes himalensis C.B.Clarke，以根入药。秋冬叶枯萎时挖根，洗净切片晒干。【功能主治】祛瘀，解毒。用于跌打损伤，疮疖肿毒，睾丸炎。
半边旗【来源】为凤尾蕨科凤尾蕨属植物半边旗Pteris semipinnata L.，以全草入药。四季可采，洗净鲜用或晒干。【功能主治】清热解毒，消肿止痛。用于细菌性痢疾，急性肠炎、黄疸型肝炎，结膜炎；外用治跌打损伤，外伤出血，疮疡疖肿，湿疹，毒蛇咬伤。
北鹤虱【来源】本品为菊科植物天名精Carpesium abrotanoides L.的干燥成熟果实。秋季果实成熟时采收，晒干，除去杂质。【功能主治】杀虫消积。用于蛔虫、蛲虫、绦虫病，虫积腹痛，小儿疳积。
矮醋栗【来源】为虎耳草科植物矮茶蔍的果实。【功能主治】祛风清热。主感冒发热，咳嗽。
八角枫花【来源】为八角枫科植物八角枫或瓜木的花。植物形态详八角枫根条。6月采。【功能主治】《四川中药志》：治头风痛及胸腹胀满。研末，蒸鸡蛋服。
伯乐树【来源】为钟萼木科植物钟萼木的树皮。夏、秋采收。【功能主治】治筋骨痛。
矮脚南【来源】为楝科植物单叶地黄连的全株。全年均可采，洗净，鲜用或晒干。【功能主治】清热解毒；活血止痛。主黄疸型肝炎；疮痈；跌打损伤；胃痛。
阿里红【来源】真菌类多孔菌科层孔菌属苦自蹄Fomes officinalis(Vill.ex Fr.)Ames，以子实体入药。夏秋采，除去粗皮晒干或搓碎。【功能主治】温肺化痰，降气平喘，祛风除湿，活血消肿，利尿，解蛇毒。用于咳嗽，哮喘，胃痛，胃酸过多，尿路结石，肾炎，慢性风湿性关节炎，咽喉炎，牙周炎，毒蛇咬伤。
凹头苋【来源】苋科苋属植物凹头苋Amaranthus ascendens Loisel.，以全草和种子入药。【功能主治】清热利湿。用于肠炎，痢疾，咽炎，乳腺炎，痔疮肿痛出血，毒蛇咬伤。
小叶黑面叶【来源】大戟科山漆茎属植物小叶黑面叶Breynia patens Benth.，以根及叶入药。根全年可采，洗净晒干，或鲜用；叶夏季采摘，晒干。【功能主治】清热解毒，止血止痛。用于感冒发热，扁桃体炎，咽喉炎，急性胃肠炎，痢疾，月经过多，崩漏，白带，痛经；外用治外伤出血，疮疖，湿疹，皮肤瘙痒，烧伤。
发明内容
本发明旨在提供一种治疗伪膜性肠炎的中药，通过选择合适的药材及其配比，达到安全有效治愈伪膜性肠炎的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗伪膜性肠炎的中药，其特征在于，由以下重量配比的药材制备而成：白叶火草8份、千屈菜12份、午时花14份、泥胡菜10份、白龙穿彩12份、芦子兰14份、白金古榄15份、布朗耳蕨10份、实葫芦12份、半边旗10份、北鹤虱8份、矮醋栗8份、八角枫花12份、伯乐树10份、矮脚南9份、阿里红12份、凹头苋10份、小叶黑面叶14份。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2009年1月-2011年11月间共收集94例伪膜性肠炎的门诊患者，年龄22-58岁，病程1-5年。随机分为：治疗组64例，空白组30例。两组年龄、病情等资料无显著性差异，具有可比性。
2、试验方法
2.1治疗组口服本发明按照具体实施例1制得的胶囊，早晚各一次。疗程3天。
2.2空白组口服安慰剂胶囊，早晚各一次。疗程3天。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状全部消失，试验室检查正常。好转：临床症状减轻，病情得到控制，实验室检查改善或正常。无效：临床症状无明显好转或加重。
3.2治疗统计结果见表1。
表1两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 不良反应例 | 总有效率(％) |
| 治疗组 | 64 | 13(20.3％) | 36(56.3％) | 15(23.4％) | 0 | 76.6％ |
| 空白组 | 30 | 0 | 7(23.3％) | 23(76.7％) | 0 | 23.3％ |
可见，本发明制得的药物能够安全有效治伪膜性肠炎。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取：白叶火草8克、千屈菜12克、午时花14克、泥胡菜10克、白龙穿彩12克、芦子兰14克、白金古榄15克、布朗耳蕨10克、实葫芦12克、半边旗10克、北鹤虱8克、矮醋栗8克、八角枫花12克、伯乐树10克、矮脚南9克、阿里红12克、凹头苋10克、小叶黑面叶14克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
用于治疗伪膜性肠炎。口服，每日分早晚两次服用。
具体实施例2
称取：白叶火草8克、千屈菜12克、午时花14克、泥胡菜10克、白龙穿彩12克、芦子兰14克、白金古榄15克、布朗耳蕨10克、实葫芦12克、半边旗10克、北鹤虱8克、矮醋栗8克、八角枫花12克、伯乐树10克、矮脚南9克、阿里红12克、凹头苋10克、小叶黑面叶14克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，粉碎，即得符合正常成人1天用量的散剂。
用于治疗伪膜性肠炎。口服，每日分早晚两次服用。
具体实施例3
称取：白叶火草8克、千屈菜12克、午时花14克、泥胡菜10克、白龙穿彩12克、芦子兰14克、白金古榄15克、布朗耳蕨10克、实葫芦12克、半边旗10克、北鹤虱8克、矮醋栗8克、八角枫花12克、伯乐树10克、矮脚南9克、阿里红12克、凹头苋10克、小叶黑面叶14克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即可制得符合正常成人1天用量的颗粒剂。
用于治疗伪膜性肠炎。口服，每日分早晚两次服用。
Claims (1)
1.一种治疗伪膜性肠炎的中药，其特征在于，由以下重量配比的药材制备而成：白叶火草8份、千屈菜12份、午时花14份、泥胡菜10份、白龙穿彩12份、芦子兰14份、白金古榄15份、布朗耳蕨10份、实葫芦12份、半边旗10份、北鹤虱8份、矮醋栗8份、八角枫花12份、伯乐树10份、矮脚南9份、阿里红12份、凹头苋10份、小叶黑面叶14份。
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| CN103341041A (zh) * | 2013-06-24 | 2013-10-09 | 朱颖 | 一种治疗结肠黑变病的中药 |
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