CN103599423B - 一种治疗牙髓炎的中药 - Google Patents
一种治疗牙髓炎的中药 Download PDFInfo
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Abstract
本发明涉及一种治疗牙髓炎的中药，由以下重量配比的药材制备而成：冰草白穗17份、公鸡头叶14份、百蕊草14份、过坛龙16份、工布乌头8份、功劳木12份、白檀根16份、剪刀股10份、广玉兰20份、古羊藤18份、蛇见怕12份、女萎14份、番石榴子10份、繁缕14份、粉瘤菌15份、多腺悬钩子15份、腐婢8份。临床实验证明，本发明能够安全有效治疗牙髓炎。
Description
技术领域
本发明涉及一种中药，具体涉及一种治疗牙髓炎的中药。
背景技术
牙髓炎是指发生于牙髓组织的炎性病变。牙髓是主要包含神经血管的疏松结缔组织，位于牙齿内部的牙髓腔内。深龋、楔状缺损等牙体硬组织疾病如不能得到及时有效地控制和治疗，均可引发牙髓炎，成为口腔中最为多发和常见的疾病之一。可由牙髓充血发展而来，也可由慢性牙髓炎急性发作而来。牙髓炎症最主要的病因就是感染，当牙体硬组织因各种原因遭受破坏时细菌就可侵入并感染牙髓。其中龋病是引起牙体硬组织丧失的最常见病因。
对于牙髓炎目前尚缺少公认安全有效的治疗药物。
本发明中药所涉及药材的研究现状如下：
冰草白穗【来源】为禾本科植物赖草的带菌果穗。秋季采收。【功能主治】清热利湿。主淋证；赤白带下。
公鸡头叶【来源】为鳞毛蕨科植物贯众的叶。全年均可采收，摘取叶，洗净，鲜用或晒干。【功能主治】凉血止血；清热利湿。主崩漏；白带；刀伤出血；烫火伤。
百蕊草【来源】为檀香科百蕊草属植物百蕊草Thesium chinense Turcz.的全草。夏秋采集，洗净晒干。【功能主治】清热解毒，解署。用于肠炎，肺脓疡，扁桃体炎，中署，急性乳腺炎，淋巴结结核，急性膀胱炎。
过坛龙【来源】为铁线蕨科植物扇叶铁线蕨的全草或根茎。全年可采，鲜用或晒干。【功能主治】清热，利湿，消瘀，散肿。治急性传染性肝炎，痢疾，腹泻，砂淋，吐血，便血，瘰疬，跌打损伤，烫伤，外伤出血，疔疮。
工布乌头【来源】为毛茛科植物工布乌头的块根。9-10月采挖根部，附去须根，洗净，切片，晒干。【功能主治】祛风除湿；止痛。主风湿关节疼痛；跌打损伤；毒虫咬伤。
功劳木【来源】为小檗科植物阔叶十大功劳、细叶十大功劳的茎或茎皮。6月采果实，晒干，去净杂质，晒至足干为度。【功能主治】清热；燥湿；解毒。主肺热咳嗽；黄疸；泄泻；痢疾；目赤肿痛；疮疡；湿疹；烫伤。
白檀根【来源】为山矾科植物白檀的根。【功能主治】《浙江中药资源名录》：散风解毒，并治腹内瘤肿。
剪刀股【来源】菊科苦荬菜属植物剪刀股Ixeris debilis A.Gray ，以全草入药。夏秋采收，鲜用或晒干。【功能主治】清热凉血，利尿消肿。用于肺热咳嗽，喉痛，口腔溃疡，急性结膜炎，阑尾炎，水肿，小便不利；外用治乳腺炎，疮疖肿毒，皮肤瘙痒。
广玉兰【来源】为木兰科植物荷花的花和树皮。春季采收术开放的花蕾，白天曝晒，晚上发汗，五成平时，再晒至全干。树皮随时可采。【功能主治】祛风散寒；行气止痛。主外感风寒；头痛鼻塞；脘腹胀痛；呕吐腹泻；高血压；偏头痛。
古羊藤【来源】为双子叶植物药萝藦科植物马连鞍的根。全年可采，洗净，切片，晒干或鲜用。【功能主治】清热解毒；散瘀止痛。主感冒发热；痢疾；胃痛；腹痛；跌打瘀痛；毒蛇咬伤。
蛇见怕【来源】苋科杯苋属植物杯苋，以根或全草入药。四季可采，鲜用或晒干。【功能主治】清热解毒。用于细菌性痢疾。全草：消积除痰，消肿止痛。用于小儿疳积，肝脾肿大，肺结核，蛇咬伤，跌打损伤，疮疡肿毒。
女萎【来源】毛茛科铁丝莲属植物女萎Clematis apiifolia DC.，以根、茎藤或全株入药。秋季采收，扎成小把，晒干。【功能主治】消炎消肿，利尿通乳。用于肠炎，痢疾，甲状腺肿大，风湿关节疼痛，尿路感染，乳汁不下。
番石榴子【来源】为桃金娘科植物番石榴的根皮及树皮。秋季果熟时，收集种子，晒干。【功能主治】止痛；止泻。主腹痛；泻痢。
繁缕【来源】为石竹科植物繁缕的全草。春、夏、秋季花开时采集，去尽泥土，晒干。【功能主治】清热解毒;凉血消痈;活血止痛;下乳;。主痢疾;肠痈;肺痈;乳痈;疔疮肿毒；痔疮肿痛；出血；跌打伤痛；产后瘀滞腹痛；乳汁不下。
粉瘤菌【来源】为假丝菌科真菌粉瘤菌的子实体。春、夏季采，洗净，鲜用或晒干。【功能主治】清热消炎。主粘膜发炎。
多腺悬钩子【来源】为虎耳草科植物钻地风的根皮,双子叶植物药蔷薇科植物多腺悬钩子的根、叶。全年可采，挖取根部，剥取根皮，晒干。【功能主治】祛风除湿、补肾壮阳。用于风湿痛，可用于治疗肾虚、阳痿、月经不调诸症。
腐婢【来源】为马鞭草科植物豆腐柴的茎、叶。春、夏、秋均可采收，鲜用或晒干。【功能主治】清热解毒。主疟疾；泄泻；痢疾；醉酒头痛；痈肿，疔疮；丹毒；蛇虫咬伤；创伤出血。
发明内容
本发明旨在提供一种治疗牙髓炎的中药，通过选择合适的药材及其配比，达到安全有效治愈牙髓炎的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗牙髓炎的中药，其特征在于，由以下重量配比的药材制备而成：冰草白穗17份、公鸡头叶14份、百蕊草14份、过坛龙16份、工布乌头8份、功劳木12份、白檀根16份、剪刀股10份、广玉兰20份、古羊藤18份、蛇见怕12份、女萎14份、番石榴子10份、繁缕14份、粉瘤菌15份、多腺悬钩子15份、腐婢8份。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取：冰草白穗17克、公鸡头叶14克、百蕊草14克、过坛龙16克、工布乌头8克、功劳木12克、白檀根16克、剪刀股10克、广玉兰20克、古羊藤18克、蛇见怕12克、女萎14克、番石榴子10克、繁缕14克、粉瘤菌15克、多腺悬钩子15克、腐婢8克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
用于治疗牙髓炎。口服，每日分早晚两次服用。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2010年9月-2012年9月间共收集122例牙髓炎的门诊患者，年龄22-57岁，病程1-5年。随机分为：治疗组92例，空白组30例。两组年龄、病情等资料无显著性差异，具有可比性。
2、试验方法
2.1治疗组口服本发明按照具体实施例1制得的胶囊，早晚各一次。疗程30天。
2.2空白组口服安慰剂胶囊，早晚各一次。疗程30天。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状全部消失，试验室检查正常，愈后观察三个月未见复发。好转：临床症状减轻，病情得到控制，实验室检查改善或正常。无效：临床症状无明显好转或加重。
3.2治疗统计结果见表1。
表1 两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 总有效率(%) | 不良反应例 |
| 治疗组 | 92 | 17（18.5%） | 55（59.8%) | 20（21.7%) | 78.3% | 0 |
| 空白组 | 30 | 0 | 5（16.7%） | 25（83.3%） | 16.7% | 0 |
可见，本发明制得的药物能够安全有效治疗牙髓炎。
具体实施例2
称取：冰草白穗17克、公鸡头叶14克、百蕊草14克、过坛龙16克、工布乌头8克、功劳木12克、白檀根16克、剪刀股10克、广玉兰20克、古羊藤18克、蛇见怕12克、女萎14克、番石榴子10克、繁缕14克、粉瘤菌15克、多腺悬钩子15克、腐婢8克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，粉碎，即得符合正常成人1天用量的散剂。
用于治疗牙髓炎。口服，每日分早晚两次服用。
具体实施例3
称取：冰草白穗17克、公鸡头叶14克、百蕊草14克、过坛龙16克、工布乌头8克、功劳木12克、白檀根16克、剪刀股10克、广玉兰20克、古羊藤18克、蛇见怕12克、女萎14克、番石榴子10克、繁缕14克、粉瘤菌15克、多腺悬钩子15克、腐婢8克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即可制得符合正常成人1天用量的颗粒剂。
用于治疗牙髓炎。口服，每日分早晚两次服用。
Claims (1)
1.一种治疗牙髓炎的中药，其特征在于，由以下重量配比的药材制备而成：冰草白穗17份、公鸡头叶14份、百蕊草14份、过坛龙16份、工布乌头8份、功劳木12份、白檀根16份、剪刀股10份、广玉兰20份、古羊藤18份、蛇见怕12份、女萎14份、番石榴子10份、繁缕14份、粉瘤菌15份、多腺悬钩子15份、腐婢8份。
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| CN101317878A (zh) * | 2008-06-10 | 2008-12-10 | 王芳 | 一种治疗急性牙髓炎的汤剂药物 |
| CN102512590A (zh) * | 2012-01-12 | 2012-06-27 | 山东大学 | 一种治疗可复性牙髓炎的中药及制备方法 |
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| CN101317878A (zh) * | 2008-06-10 | 2008-12-10 | 王芳 | 一种治疗急性牙髓炎的汤剂药物 |
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