CN1035845A - 转化生长因子β2的克隆和表达 - Google Patents
转化生长因子β2的克隆和表达 Download PDFInfo
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- General Health & Medical Sciences (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
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US10675287A | 1987-10-06 | 1987-10-06 | |
US106,752 | 1987-10-06 | ||
US14826788A | 1988-01-25 | 1988-01-25 | |
US148,267 | 1988-01-25 | ||
US23406588A | 1988-08-18 | 1988-08-18 | |
US234,065 | 1988-08-18 |
Publications (1)
Publication Number | Publication Date |
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CN1035845A true CN1035845A (zh) | 1989-09-27 |
Family
ID=27380183
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN88109075A Pending CN1035845A (zh) | 1987-10-06 | 1988-10-05 | 转化生长因子β2的克隆和表达 |
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Country | Link |
---|---|
JP (1) | JPH02444A (el) |
KR (1) | KR970001236B1 (el) |
CN (1) | CN1035845A (el) |
AT (1) | AT398433B (el) |
BE (1) | BE1002693A5 (el) |
CH (1) | CH680002A5 (el) |
DE (1) | DE3833897C2 (el) |
DK (1) | DK556388A (el) |
ES (1) | ES2012556A6 (el) |
FI (1) | FI884546A (el) |
FR (1) | FR2621324B1 (el) |
GB (1) | GB2210620B8 (el) |
GR (1) | GR1000492B (el) |
IE (1) | IE60918B1 (el) |
IL (1) | IL87877A0 (el) |
IT (1) | IT1227957B (el) |
MY (1) | MY103779A (el) |
NL (1) | NL8802442A (el) |
NO (1) | NO884429L (el) |
NZ (1) | NZ226486A (el) |
PT (1) | PT88670B (el) |
SE (1) | SE8803528L (el) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100389120C (zh) * | 2005-04-12 | 2008-05-21 | 中国人民解放军第三军医大学野战外科研究所 | 封闭TGF-β1的反义寡核苷酸及其在制备治疗纤维化相关疾病药物中的用途 |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5221620A (en) * | 1987-10-06 | 1993-06-22 | Oncogen | Cloning and expression of transforming growth factor β2 |
US5445941A (en) * | 1993-06-21 | 1995-08-29 | Eli Lilly And Company | Method for screening anti-osteoporosis agents |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0169016B2 (en) * | 1984-07-16 | 2004-04-28 | Celtrix Pharmaceuticals, Inc. | Polypeptide cartilage-inducing factors found in bone |
IL78197A (en) * | 1985-03-22 | 1991-07-18 | Genentech Inc | Nucleic acid encoding tgf-beta and its uses |
WO1988003807A2 (en) * | 1986-11-17 | 1988-06-02 | Sandoz Ag | Production and use of a novel t-cell suppressor factor |
US4931548A (en) * | 1987-01-30 | 1990-06-05 | Techne Corporation | Heterodimer form of transforming growth factor-beta |
AU1340688A (en) * | 1987-01-30 | 1988-08-24 | Techne Corporation | Transforming growth factor-beta |
AU1539188A (en) * | 1987-05-04 | 1988-11-10 | Bristol-Myers Squibb Company | TGF-B2 and novel compositions having anti-neoplastic activity |
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1988
- 1988-09-29 IL IL87877A patent/IL87877A0/xx active Protection Beyond IP Right Term
- 1988-10-03 FI FI884546A patent/FI884546A/fi not_active IP Right Cessation
- 1988-10-04 MY MYPI88001108A patent/MY103779A/en unknown
- 1988-10-04 PT PT88670A patent/PT88670B/pt not_active IP Right Cessation
- 1988-10-05 IE IE301888A patent/IE60918B1/en not_active IP Right Cessation
- 1988-10-05 CN CN88109075A patent/CN1035845A/zh active Pending
- 1988-10-05 SE SE8803528A patent/SE8803528L/ not_active Application Discontinuation
- 1988-10-05 DK DK556388A patent/DK556388A/da not_active Application Discontinuation
- 1988-10-05 NO NO88884429A patent/NO884429L/no unknown
- 1988-10-05 AT AT0245488A patent/AT398433B/de not_active IP Right Cessation
- 1988-10-05 CH CH3702/88A patent/CH680002A5/fr not_active IP Right Cessation
- 1988-10-05 NL NL8802442A patent/NL8802442A/nl not_active Application Discontinuation
- 1988-10-05 FR FR8813046A patent/FR2621324B1/fr not_active Expired - Fee Related
- 1988-10-05 DE DE3833897A patent/DE3833897C2/de not_active Expired - Fee Related
- 1988-10-05 KR KR1019880012986A patent/KR970001236B1/ko active IP Right Grant
- 1988-10-05 ES ES8803023A patent/ES2012556A6/es not_active Expired - Lifetime
- 1988-10-05 BE BE8801141A patent/BE1002693A5/fr not_active IP Right Cessation
- 1988-10-05 GR GR880100660A patent/GR1000492B/el unknown
- 1988-10-06 GB GB8823448A patent/GB2210620B8/en not_active Expired - Fee Related
- 1988-10-06 NZ NZ226486A patent/NZ226486A/xx unknown
- 1988-10-06 JP JP63251011A patent/JPH02444A/ja active Pending
- 1988-10-06 IT IT8822213A patent/IT1227957B/it active
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100389120C (zh) * | 2005-04-12 | 2008-05-21 | 中国人民解放军第三军医大学野战外科研究所 | 封闭TGF-β1的反义寡核苷酸及其在制备治疗纤维化相关疾病药物中的用途 |
Also Published As
Publication number | Publication date |
---|---|
FI884546A0 (fi) | 1988-10-03 |
GB2210620A (en) | 1989-06-14 |
NO884429L (no) | 1989-04-07 |
IE883018L (en) | 1989-04-06 |
KR970001236B1 (ko) | 1997-02-04 |
ES2012556A6 (es) | 1990-04-01 |
DK556388D0 (da) | 1988-10-05 |
DE3833897C2 (de) | 1997-03-20 |
DK556388A (da) | 1989-04-07 |
GB2210620B (en) | 1992-07-08 |
GB8823448D0 (en) | 1988-11-16 |
NO884429D0 (no) | 1988-10-05 |
IT8822213A0 (it) | 1988-10-06 |
FR2621324B1 (fr) | 1994-02-18 |
PT88670B (pt) | 1992-12-31 |
JPH02444A (ja) | 1990-01-05 |
IE60918B1 (en) | 1994-08-24 |
GB2210620B8 (en) | 1995-07-17 |
GR1000492B (el) | 1992-07-30 |
ATA245488A (de) | 1994-04-15 |
BE1002693A5 (fr) | 1991-05-07 |
IT1227957B (it) | 1991-05-20 |
IL87877A0 (en) | 1989-03-31 |
KR890006814A (ko) | 1989-06-16 |
FR2621324A1 (fr) | 1989-04-07 |
SE8803528L (sv) | 1989-04-07 |
CH680002A5 (el) | 1992-05-29 |
MY103779A (en) | 1993-09-30 |
DE3833897A1 (de) | 1989-05-03 |
AT398433B (de) | 1994-12-27 |
NL8802442A (nl) | 1989-05-01 |
NZ226486A (en) | 1991-08-27 |
SE8803528D0 (sv) | 1988-10-05 |
FI884546A (fi) | 1989-04-07 |
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