CN1035845A - 转化生长因子β2的克隆和表达 - Google Patents

转化生长因子β2的克隆和表达 Download PDF

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Publication number
CN1035845A
CN1035845A CN88109075A CN88109075A CN1035845A CN 1035845 A CN1035845 A CN 1035845A CN 88109075 A CN88109075 A CN 88109075A CN 88109075 A CN88109075 A CN 88109075A CN 1035845 A CN1035845 A CN 1035845A
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CN
China
Prior art keywords
tgf
amino
transforminggrowthfactor
nucleotide
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN88109075A
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English (en)
Chinese (zh)
Inventor
安东尼·F·佩奇奥
琳达·麦迪逊
南希·韦伯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oncogen LP
Original Assignee
Oncogen LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogen LP filed Critical Oncogen LP
Publication of CN1035845A publication Critical patent/CN1035845A/zh
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/495Transforming growth factor [TGF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN88109075A 1987-10-06 1988-10-05 转化生长因子β2的克隆和表达 Pending CN1035845A (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US10675287A 1987-10-06 1987-10-06
US106,752 1987-10-06
US14826788A 1988-01-25 1988-01-25
US148,267 1988-01-25
US23406588A 1988-08-18 1988-08-18
US234,065 1988-08-18

Publications (1)

Publication Number Publication Date
CN1035845A true CN1035845A (zh) 1989-09-27

Family

ID=27380183

Family Applications (1)

Application Number Title Priority Date Filing Date
CN88109075A Pending CN1035845A (zh) 1987-10-06 1988-10-05 转化生长因子β2的克隆和表达

Country Status (22)

Country Link
JP (1) JPH02444A (el)
KR (1) KR970001236B1 (el)
CN (1) CN1035845A (el)
AT (1) AT398433B (el)
BE (1) BE1002693A5 (el)
CH (1) CH680002A5 (el)
DE (1) DE3833897C2 (el)
DK (1) DK556388A (el)
ES (1) ES2012556A6 (el)
FI (1) FI884546A (el)
FR (1) FR2621324B1 (el)
GB (1) GB2210620B8 (el)
GR (1) GR1000492B (el)
IE (1) IE60918B1 (el)
IL (1) IL87877A0 (el)
IT (1) IT1227957B (el)
MY (1) MY103779A (el)
NL (1) NL8802442A (el)
NO (1) NO884429L (el)
NZ (1) NZ226486A (el)
PT (1) PT88670B (el)
SE (1) SE8803528L (el)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100389120C (zh) * 2005-04-12 2008-05-21 中国人民解放军第三军医大学野战外科研究所 封闭TGF-β1的反义寡核苷酸及其在制备治疗纤维化相关疾病药物中的用途

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5221620A (en) * 1987-10-06 1993-06-22 Oncogen Cloning and expression of transforming growth factor β2
US5445941A (en) * 1993-06-21 1995-08-29 Eli Lilly And Company Method for screening anti-osteoporosis agents

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0169016B2 (en) * 1984-07-16 2004-04-28 Celtrix Pharmaceuticals, Inc. Polypeptide cartilage-inducing factors found in bone
IL78197A (en) * 1985-03-22 1991-07-18 Genentech Inc Nucleic acid encoding tgf-beta and its uses
WO1988003807A2 (en) * 1986-11-17 1988-06-02 Sandoz Ag Production and use of a novel t-cell suppressor factor
US4931548A (en) * 1987-01-30 1990-06-05 Techne Corporation Heterodimer form of transforming growth factor-beta
AU1340688A (en) * 1987-01-30 1988-08-24 Techne Corporation Transforming growth factor-beta
AU1539188A (en) * 1987-05-04 1988-11-10 Bristol-Myers Squibb Company TGF-B2 and novel compositions having anti-neoplastic activity

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100389120C (zh) * 2005-04-12 2008-05-21 中国人民解放军第三军医大学野战外科研究所 封闭TGF-β1的反义寡核苷酸及其在制备治疗纤维化相关疾病药物中的用途

Also Published As

Publication number Publication date
FI884546A0 (fi) 1988-10-03
GB2210620A (en) 1989-06-14
NO884429L (no) 1989-04-07
IE883018L (en) 1989-04-06
KR970001236B1 (ko) 1997-02-04
ES2012556A6 (es) 1990-04-01
DK556388D0 (da) 1988-10-05
DE3833897C2 (de) 1997-03-20
DK556388A (da) 1989-04-07
GB2210620B (en) 1992-07-08
GB8823448D0 (en) 1988-11-16
NO884429D0 (no) 1988-10-05
IT8822213A0 (it) 1988-10-06
FR2621324B1 (fr) 1994-02-18
PT88670B (pt) 1992-12-31
JPH02444A (ja) 1990-01-05
IE60918B1 (en) 1994-08-24
GB2210620B8 (en) 1995-07-17
GR1000492B (el) 1992-07-30
ATA245488A (de) 1994-04-15
BE1002693A5 (fr) 1991-05-07
IT1227957B (it) 1991-05-20
IL87877A0 (en) 1989-03-31
KR890006814A (ko) 1989-06-16
FR2621324A1 (fr) 1989-04-07
SE8803528L (sv) 1989-04-07
CH680002A5 (el) 1992-05-29
MY103779A (en) 1993-09-30
DE3833897A1 (de) 1989-05-03
AT398433B (de) 1994-12-27
NL8802442A (nl) 1989-05-01
NZ226486A (en) 1991-08-27
SE8803528D0 (sv) 1988-10-05
FI884546A (fi) 1989-04-07

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