GB2210620B8 - Cloning and expression of transforming growth factor beta2 - Google Patents

Cloning and expression of transforming growth factor beta2

Info

Publication number
GB2210620B8
GB2210620B8 GB8823448A GB8823448A GB2210620B8 GB 2210620 B8 GB2210620 B8 GB 2210620B8 GB 8823448 A GB8823448 A GB 8823448A GB 8823448 A GB8823448 A GB 8823448A GB 2210620 B8 GB2210620 B8 GB 2210620B8
Authority
GB
United Kingdom
Prior art keywords
cloning
expression
growth factor
transforming growth
factor beta2
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB8823448A
Other versions
GB2210620B (en
GB8823448D0 (en
GB2210620A (en
Inventor
Anthony F Purchio
Linda Madisen
Nancy Webb
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oncogen LP
Original Assignee
Oncogen LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogen LP filed Critical Oncogen LP
Publication of GB8823448D0 publication Critical patent/GB8823448D0/en
Publication of GB2210620A publication Critical patent/GB2210620A/en
Publication of GB2210620B publication Critical patent/GB2210620B/en
Application granted granted Critical
Publication of GB2210620B8 publication Critical patent/GB2210620B8/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/495Transforming growth factor [TGF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
GB8823448A 1987-10-06 1988-10-06 Cloning and expression of transforming growth factor beta2 Expired - Fee Related GB2210620B8 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10675287A 1987-10-06 1987-10-06
US14826788A 1988-01-25 1988-01-25
US23406588A 1988-08-18 1988-08-18

Publications (4)

Publication Number Publication Date
GB8823448D0 GB8823448D0 (en) 1988-11-16
GB2210620A GB2210620A (en) 1989-06-14
GB2210620B GB2210620B (en) 1992-07-08
GB2210620B8 true GB2210620B8 (en) 1995-07-17

Family

ID=27380183

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8823448A Expired - Fee Related GB2210620B8 (en) 1987-10-06 1988-10-06 Cloning and expression of transforming growth factor beta2

Country Status (22)

Country Link
JP (1) JPH02444A (en)
KR (1) KR970001236B1 (en)
CN (1) CN1035845A (en)
AT (1) AT398433B (en)
BE (1) BE1002693A5 (en)
CH (1) CH680002A5 (en)
DE (1) DE3833897C2 (en)
DK (1) DK556388A (en)
ES (1) ES2012556A6 (en)
FI (1) FI884546A (en)
FR (1) FR2621324B1 (en)
GB (1) GB2210620B8 (en)
GR (1) GR1000492B (en)
IE (1) IE60918B1 (en)
IL (1) IL87877A0 (en)
IT (1) IT1227957B (en)
MY (1) MY103779A (en)
NL (1) NL8802442A (en)
NO (1) NO884429L (en)
NZ (1) NZ226486A (en)
PT (1) PT88670B (en)
SE (1) SE8803528L (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5221620A (en) * 1987-10-06 1993-06-22 Oncogen Cloning and expression of transforming growth factor β2
US5445941A (en) * 1993-06-21 1995-08-29 Eli Lilly And Company Method for screening anti-osteoporosis agents
CN100389120C (en) * 2005-04-12 2008-05-21 中国人民解放军第三军医大学野战外科研究所 Sealing TGF-betal antisensedingonucleotides and its use in preparing medicine for treating fibrillation related disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE128715T1 (en) * 1984-07-16 1995-10-15 Celtrix Pharma POLYPEPTIDE-INDUCING FACTORS IN BONE AND CARTILAGE.
IL78197A (en) * 1985-03-22 1991-07-18 Genentech Inc Nucleic acid encoding tgf-beta and its uses
NZ222569A (en) * 1986-11-17 1990-08-28 Sandoz Ltd Production of glioblastoma-derived t cell suppressor factor (g-tsf) using recombinant techniques
US4931548A (en) * 1987-01-30 1990-06-05 Techne Corporation Heterodimer form of transforming growth factor-beta
AU1340688A (en) * 1987-01-30 1988-08-24 Techne Corporation Transforming growth factor-beta
AU1539188A (en) * 1987-05-04 1988-11-10 Bristol-Myers Squibb Company TGF-B2 and novel compositions having anti-neoplastic activity

Also Published As

Publication number Publication date
NO884429L (en) 1989-04-07
KR970001236B1 (en) 1997-02-04
GB2210620B (en) 1992-07-08
FI884546A0 (en) 1988-10-03
GB8823448D0 (en) 1988-11-16
CN1035845A (en) 1989-09-27
IE60918B1 (en) 1994-08-24
JPH02444A (en) 1990-01-05
SE8803528L (en) 1989-04-07
NZ226486A (en) 1991-08-27
ES2012556A6 (en) 1990-04-01
DK556388D0 (en) 1988-10-05
DE3833897A1 (en) 1989-05-03
MY103779A (en) 1993-09-30
FR2621324A1 (en) 1989-04-07
IT8822213A0 (en) 1988-10-06
BE1002693A5 (en) 1991-05-07
SE8803528D0 (en) 1988-10-05
CH680002A5 (en) 1992-05-29
AT398433B (en) 1994-12-27
DK556388A (en) 1989-04-07
NL8802442A (en) 1989-05-01
IE883018L (en) 1989-04-06
FI884546A (en) 1989-04-07
ATA245488A (en) 1994-04-15
DE3833897C2 (en) 1997-03-20
NO884429D0 (en) 1988-10-05
GR1000492B (en) 1992-07-30
IL87877A0 (en) 1989-03-31
IT1227957B (en) 1991-05-20
KR890006814A (en) 1989-06-16
GB2210620A (en) 1989-06-14
FR2621324B1 (en) 1994-02-18
PT88670B (en) 1992-12-31

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19921008

728C Application made for restoration (sect. 28/1977)
711H Case decided by the comptr. ** correction allowed (sect. 117/1977)
728A Order made restoring the patent (sect. 28/1977)
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19971006