NO884429L - CLONING AND EXPRESSION OF TRANSFORMING GROWTH FACTOR BETA - Google Patents

CLONING AND EXPRESSION OF TRANSFORMING GROWTH FACTOR BETA

Info

Publication number
NO884429L
NO884429L NO88884429A NO884429A NO884429L NO 884429 L NO884429 L NO 884429L NO 88884429 A NO88884429 A NO 88884429A NO 884429 A NO884429 A NO 884429A NO 884429 L NO884429 L NO 884429L
Authority
NO
Norway
Prior art keywords
expression
cloning
growth factor
transforming growth
factor beta
Prior art date
Application number
NO88884429A
Other languages
Norwegian (no)
Other versions
NO884429D0 (en
Inventor
Anthony F Purchio
Linda Madisen
Nancy Webb
Original Assignee
Oncogen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogen filed Critical Oncogen
Publication of NO884429D0 publication Critical patent/NO884429D0/en
Publication of NO884429L publication Critical patent/NO884429L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity

Abstract

cDNA-kloner som koder for TGF-S2, anvendes til oppbygning av ekspresjonsvektorer soa kan styre ekspresjonen av utviklet biologisk aktiv TGF-62 i transfiserte (XO-celler. Nucleotidsekvensen som koder for TGF-B2, omfatter i alt vesentlig den i figur la eller b avbildede sekvens.cDNA clones encoding TGF-S2 are used to build expression vectors so that they can control the expression of developed biologically active TGF-62 in transfected (XO cells. The nucleotide sequence encoding TGF-B2 essentially comprises the b depicted sequence.

NO88884429A 1987-10-06 1988-10-05 CLONING AND EXPRESSION OF TRANSFORMING GROWTH FACTOR BETA NO884429L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10675287A 1987-10-06 1987-10-06
US14826788A 1988-01-25 1988-01-25
US23406588A 1988-08-18 1988-08-18

Publications (2)

Publication Number Publication Date
NO884429D0 NO884429D0 (en) 1988-10-05
NO884429L true NO884429L (en) 1989-04-07

Family

ID=27380183

Family Applications (1)

Application Number Title Priority Date Filing Date
NO88884429A NO884429L (en) 1987-10-06 1988-10-05 CLONING AND EXPRESSION OF TRANSFORMING GROWTH FACTOR BETA

Country Status (22)

Country Link
JP (1) JPH02444A (en)
KR (1) KR970001236B1 (en)
CN (1) CN1035845A (en)
AT (1) AT398433B (en)
BE (1) BE1002693A5 (en)
CH (1) CH680002A5 (en)
DE (1) DE3833897C2 (en)
DK (1) DK556388A (en)
ES (1) ES2012556A6 (en)
FI (1) FI884546A (en)
FR (1) FR2621324B1 (en)
GB (1) GB2210620B8 (en)
GR (1) GR1000492B (en)
IE (1) IE60918B1 (en)
IL (1) IL87877A0 (en)
IT (1) IT1227957B (en)
MY (1) MY103779A (en)
NL (1) NL8802442A (en)
NO (1) NO884429L (en)
NZ (1) NZ226486A (en)
PT (1) PT88670B (en)
SE (1) SE8803528L (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5221620A (en) * 1987-10-06 1993-06-22 Oncogen Cloning and expression of transforming growth factor β2
US5445941A (en) * 1993-06-21 1995-08-29 Eli Lilly And Company Method for screening anti-osteoporosis agents
CN100389120C (en) * 2005-04-12 2008-05-21 中国人民解放军第三军医大学野战外科研究所 Sealing TGF-betal antisensedingonucleotides and its use in preparing medicine for treating fibrillation related disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE128715T1 (en) * 1984-07-16 1995-10-15 Celtrix Pharma POLYPEPTIDE-INDUCING FACTORS IN BONE AND CARTILAGE.
IL78197A (en) * 1985-03-22 1991-07-18 Genentech Inc Nucleic acid encoding tgf-beta and its uses
NZ222569A (en) * 1986-11-17 1990-08-28 Sandoz Ltd Production of glioblastoma-derived t cell suppressor factor (g-tsf) using recombinant techniques
US4931548A (en) * 1987-01-30 1990-06-05 Techne Corporation Heterodimer form of transforming growth factor-beta
AU1340688A (en) * 1987-01-30 1988-08-24 Techne Corporation Transforming growth factor-beta
AU1539188A (en) * 1987-05-04 1988-11-10 Bristol-Myers Squibb Company TGF-B2 and novel compositions having anti-neoplastic activity

Also Published As

Publication number Publication date
KR970001236B1 (en) 1997-02-04
GB2210620B (en) 1992-07-08
FI884546A0 (en) 1988-10-03
GB8823448D0 (en) 1988-11-16
CN1035845A (en) 1989-09-27
IE60918B1 (en) 1994-08-24
JPH02444A (en) 1990-01-05
SE8803528L (en) 1989-04-07
NZ226486A (en) 1991-08-27
ES2012556A6 (en) 1990-04-01
DK556388D0 (en) 1988-10-05
DE3833897A1 (en) 1989-05-03
MY103779A (en) 1993-09-30
FR2621324A1 (en) 1989-04-07
IT8822213A0 (en) 1988-10-06
BE1002693A5 (en) 1991-05-07
SE8803528D0 (en) 1988-10-05
CH680002A5 (en) 1992-05-29
GB2210620B8 (en) 1995-07-17
AT398433B (en) 1994-12-27
DK556388A (en) 1989-04-07
NL8802442A (en) 1989-05-01
IE883018L (en) 1989-04-06
FI884546A (en) 1989-04-07
ATA245488A (en) 1994-04-15
DE3833897C2 (en) 1997-03-20
NO884429D0 (en) 1988-10-05
GR1000492B (en) 1992-07-30
IL87877A0 (en) 1989-03-31
IT1227957B (en) 1991-05-20
KR890006814A (en) 1989-06-16
GB2210620A (en) 1989-06-14
FR2621324B1 (en) 1994-02-18
PT88670B (en) 1992-12-31

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