CN103571906B - 一种利用微藻高效生产虾青素的新方法 - Google Patents
一种利用微藻高效生产虾青素的新方法 Download PDFInfo
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- CN103571906B CN103571906B CN201210264946.XA CN201210264946A CN103571906B CN 103571906 B CN103571906 B CN 103571906B CN 201210264946 A CN201210264946 A CN 201210264946A CN 103571906 B CN103571906 B CN 103571906B
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
- C12P7/26—Ketones
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/12—Unicellular algae; Culture media therefor
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- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
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- Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
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- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
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- Preparation Of Compounds By Using Micro-Organisms (AREA)
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Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210264946.XA CN103571906B (zh) | 2012-07-27 | 2012-07-27 | 一种利用微藻高效生产虾青素的新方法 |
| EP13823422.4A EP2878676A4 (en) | 2012-07-27 | 2013-09-26 | PROCESS WITH MICROALGEN FOR THE HIGHLY EFFICIENT MANUFACTURE OF ASTAXANTHINE |
| US14/417,166 US20150252391A1 (en) | 2012-07-27 | 2013-09-26 | Method using microalgae for high-efficiency production of astaxanthin |
| PCT/CN2013/084262 WO2014015841A2 (zh) | 2012-07-27 | 2013-09-26 | 一种利用微藻高效生产虾青素的新方法 |
| BR112015001637A BR112015001637A2 (pt) | 2012-07-27 | 2013-09-26 | método usando microalgas para produção com eficiência elevada de astaxantina |
| AU2013295436A AU2013295436A1 (en) | 2012-07-27 | 2013-09-26 | Method using micro-algae for high-efficiency production of astaxanthin |
| IN1606DEN2015 IN2015DN01606A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2012-07-27 | 2013-09-26 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210264946.XA CN103571906B (zh) | 2012-07-27 | 2012-07-27 | 一种利用微藻高效生产虾青素的新方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103571906A CN103571906A (zh) | 2014-02-12 |
| CN103571906B true CN103571906B (zh) | 2018-12-11 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210264946.XA Active CN103571906B (zh) | 2012-07-27 | 2012-07-27 | 一种利用微藻高效生产虾青素的新方法 |
Country Status (7)
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101725976B1 (ko) * | 2014-04-17 | 2017-04-26 | 고려대학교 산학협력단 | 고온에서 성숙포자 접종 및 철이온매개 하버-바이스 반응에 의한 해마토코쿠스 플루비알리스 내 아스타잔틴 생산량 증진방법 |
| CN103966103A (zh) * | 2014-05-26 | 2014-08-06 | 临沂大学 | 利用啤酒厂废水培养雨生红球藻的培养基及培养方法 |
| CN104263649A (zh) * | 2014-09-15 | 2015-01-07 | 李健 | 一种大规模微藻培养的方法 |
| US20180110741A1 (en) * | 2015-03-19 | 2018-04-26 | Basf Se | Astaxanthin compositions (i) |
| WO2016146803A1 (de) * | 2015-03-19 | 2016-09-22 | Basf Se | Astaxanthinzusammensetzungen (iii) |
| CN105420332A (zh) * | 2015-12-10 | 2016-03-23 | 天津科技大学 | 一种雨生红球藻高产虾青素的方法 |
| CN105462844B (zh) * | 2015-12-16 | 2019-05-03 | 中国科学院青岛生物能源与过程研究所 | 一种雨生红球藻细胞周期同步化的调控方法及其应用 |
| CN107189946B (zh) * | 2016-03-15 | 2022-07-01 | 嘉兴泽元生物制品有限责任公司 | 一种避免微藻光抑制以提高虾青素产量的方法 |
| CA3028227A1 (en) | 2016-06-30 | 2018-01-04 | Kuehnle Agrosystems, Inc. | Improved heterotrophic production methods for microbial biomass and bioproducts |
| CN106316847B (zh) * | 2016-08-16 | 2019-01-15 | 集美大学 | 一种虾青素亚油酸单酯的制备方法 |
| CN109642246A (zh) * | 2016-09-21 | 2019-04-16 | 日本水产株式会社 | 虾青素的生产方法 |
| CN106434817B (zh) * | 2016-09-29 | 2020-03-10 | 山东金晶生物技术有限公司 | 一种利用碱预处理技术提升雨生红球藻生产虾青素的方法 |
| WO2018064037A1 (en) * | 2016-09-30 | 2018-04-05 | Heliae Development Llc | Methods of applying acetate toxicity and inducing acetate uptake in microalgae cultures |
| LT3551622T (lt) | 2016-12-09 | 2021-02-25 | Vertex Pharmaceuticals Incorporated | Cistinės fibrozės transmembraninio laidumo reguliatoriaus moduliatorius, farmacinė kompozicija, gydymo būdai, ir moduliatoriaus gamybos būdas |
| WO2018227049A1 (en) | 2017-06-08 | 2018-12-13 | Vertex Pharmaceuticals Incorporated | Methods of treatment for cystic fibrosis |
| CA3068609A1 (en) | 2017-07-01 | 2019-01-10 | Vertex Pharmaceuticals Incorporated | Compositions and methods for treatment of cystic fibrosis |
| CN107384907A (zh) * | 2017-07-13 | 2017-11-24 | 荆楚理工学院 | 一种富硒虾青素小球藻粉的制备方法 |
| CA3069225A1 (en) | 2017-07-17 | 2019-01-24 | Vertex Pharmaceuticals Incorporated | Methods of treatment for cystic fibrosis |
| WO2019018395A1 (en) | 2017-07-17 | 2019-01-24 | Vertex Pharmaceuticals Incorporated | METHODS OF TREATING CYSTIC FIBROSIS |
| EP3697774B1 (en) | 2017-10-19 | 2025-09-24 | Vertex Pharmaceuticals Incorporated | Crystalline forms and compositions of cftr modulators |
| WO2019113089A1 (en) | 2017-12-04 | 2019-06-13 | Vertex Pharmaceuticals Incorporated | Compositions for treating cystic fibrosis |
| TWI810243B (zh) | 2018-02-05 | 2023-08-01 | 美商維泰克斯製藥公司 | 用於治療囊腫纖化症之醫藥組合物 |
| JP7214743B2 (ja) | 2018-02-15 | 2023-01-30 | バーテックス ファーマシューティカルズ インコーポレイテッド | 嚢胞性線維症膜コンダクタンス制御因子のモジュレーターとしての大環状分子、それらの医薬組成物、嚢胞性線維症の治療におけるそれらの使用、及びそれらの製造方法 |
| US20210139514A1 (en) | 2018-04-05 | 2021-05-13 | Vertex Pharmaceuticals Incorporated | Modulators of cystic fibrosis transmembrane conductance regulator |
| EP3774825A1 (en) | 2018-04-13 | 2021-02-17 | Vertex Pharmaceuticals Incorporated | Modulators of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator |
| CN108504619B (zh) * | 2018-06-06 | 2021-06-01 | 中国科学院海洋研究所 | 一种缓解雨生红球藻光抑制的方法 |
| IT201800006555A1 (it) * | 2018-06-21 | 2019-12-21 | Procedimento per la coltivazione di alghe, preferibilmente di microalghe | |
| CN109566393A (zh) * | 2018-12-14 | 2019-04-05 | 浙江海洋大学 | 用于提取多糖的海藻的培养方法 |
| US11377675B2 (en) | 2019-01-16 | 2022-07-05 | Kuehnle Agrosystems, Inc. | Subterranean microalgae for production of microbial biomass, substances, and compositions |
| CA3153203A1 (en) * | 2019-09-23 | 2021-04-01 | Bioalgo (Wf) Co., Ltd | Method for producing astaxanthin by heterotrophic culture of haematococcus pluvialis |
| CA3153214A1 (en) * | 2019-09-23 | 2021-04-01 | Bioalgo (Wf) Co., Ltd | Method for culturing haematococcus pluvialis to produce astaxanthin |
| WO2022194399A1 (en) | 2020-07-13 | 2022-09-22 | Idorsia Pharmaceuticals Ltd | Macrocycles as cftr modulators |
| CN111979097A (zh) * | 2020-09-04 | 2020-11-24 | 清华大学 | 一种微藻培养用光生物反应器 |
| CN112239727B (zh) * | 2020-10-15 | 2022-04-01 | 大连理工大学 | 一种基于人工智能微藻混合系统培养微藻的方法 |
| KR102535358B1 (ko) * | 2021-03-30 | 2023-05-26 | 고려대학교 산학협력단 | 초음파 자극의 도입을 통한 미세조류 유래 고부가 가치 물질 생합성 증대법 |
| CN113717917A (zh) * | 2021-06-30 | 2021-11-30 | 中国海洋大学 | 一种雨生红球藻纯种培养的联合抗生素施用方法 |
| CN113817793A (zh) * | 2021-09-14 | 2021-12-21 | 国青(浙江)科学研究有限公司 | 一种叶黄素提高雨生红球藻中虾青素含量的生产工艺 |
| CN114214386A (zh) * | 2021-12-13 | 2022-03-22 | 广东百睿盈科生物科技有限公司 | 一种异养培养小球藻生产虾青素的方法 |
| CN114214202B (zh) * | 2021-12-27 | 2024-02-13 | 广西源藻生物科技有限公司 | 异养-光诱导串联培养微藻联产叶黄素和蛋白质的方法 |
| JP7633682B2 (ja) | 2022-04-13 | 2025-02-20 | 学校法人 創価大学 | 微生物培養方法 |
| TW202421102A (zh) | 2022-09-15 | 2024-06-01 | 瑞士商愛杜西亞製藥有限公司 | 巨環cftr調節劑與cftr校正子及/或cftr增效劑之組合 |
| WO2024056779A1 (en) | 2022-09-15 | 2024-03-21 | Idorsia Pharmaceuticals Ltd | Crystalline form of (3s,7s,10r,13r)-13-benzyl-20-fluoro-7-isobutyl-n-(2-(3-methoxy-1,2,4-oxadiazol-5-yl)ethyl)-6,9-dimethyl-1,5,8,11-tetraoxo-10-(2,2,2-trifluoroethyl)-1,2,3,4,5,6,7,8,9,10,11,12,13,14-tetradecahydro-[1]oxa[4,7,10,14]tetraazacycloheptadecino[16,17-f]quinoline-3-carboxamide |
| WO2024056798A1 (en) | 2022-09-15 | 2024-03-21 | Idorsia Pharmaceuticals Ltd | Macrocyclic cftr modulators |
| WO2025186214A1 (en) | 2024-03-05 | 2025-09-12 | Idorsia Pharmaceuticals Ltd | Macrocyclic cftr modulators |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100410362C (zh) * | 2006-04-12 | 2008-08-13 | 华东理工大学 | 高密度高品质培养小球藻的方法 |
| CN102094061B (zh) * | 2010-12-01 | 2015-07-01 | 华东理工大学 | 一种利用微藻生产叶黄素的方法 |
| CN102021208A (zh) * | 2010-11-16 | 2011-04-20 | 华东理工大学 | 一种快速积累微藻胞内油脂的方法 |
| CN101979498B (zh) * | 2010-12-01 | 2016-05-04 | 华东理工大学 | 一种微藻高产率异养培养的方法 |
| CN102154110B (zh) * | 2011-01-27 | 2016-03-02 | 华东理工大学 | 一种高产率的微藻培养方法 |
-
2012
- 2012-07-27 CN CN201210264946.XA patent/CN103571906B/zh active Active
-
2013
- 2013-09-26 BR BR112015001637A patent/BR112015001637A2/pt not_active IP Right Cessation
- 2013-09-26 IN IN1606DEN2015 patent/IN2015DN01606A/en unknown
- 2013-09-26 US US14/417,166 patent/US20150252391A1/en not_active Abandoned
- 2013-09-26 WO PCT/CN2013/084262 patent/WO2014015841A2/zh active Application Filing
- 2013-09-26 AU AU2013295436A patent/AU2013295436A1/en not_active Abandoned
- 2013-09-26 EP EP13823422.4A patent/EP2878676A4/en not_active Withdrawn
Non-Patent Citations (1)
| Title |
|---|
| 雨生红球藻异养转化产虾青素的条件研究;张睿钦等;《浙江大学学报(农业与生命科学版)》;20111120;第37卷(第6期);参见第624-629页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2878676A2 (en) | 2015-06-03 |
| WO2014015841A2 (zh) | 2014-01-30 |
| IN2015DN01606A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2015-07-03 |
| WO2014015841A3 (zh) | 2014-03-20 |
| US20150252391A1 (en) | 2015-09-10 |
| BR112015001637A2 (pt) | 2017-07-04 |
| AU2013295436A1 (en) | 2015-03-19 |
| EP2878676A4 (en) | 2016-05-25 |
| CN103571906A (zh) | 2014-02-12 |
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| Date | Code | Title | Description |
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Effective date of registration: 20200723 Address after: 678206 Huaxing Industrial Park, Youwang Town, Shidian County, Baoshan City, Yunnan Province Patentee after: Yunnan Baoshan Zeyuan algae industry health technology Co.,Ltd. Address before: 200237 Shanghai City, Xuhui District Shanghai City Jia Chuan Road No. 245 Building No. 1 Room 301 Co-patentee before: JIAXING ZEYUAN BIOLOGICAL PRODUCTS Co.,Ltd. Patentee before: SHANGHAI ZEYUAN MARINE BIOTECHNOLOGY Co.,Ltd. |
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Effective date of registration: 20210812 Address after: 201207 room 601ac-05, building 2, No. 351, GuoShouJing Road, pilot Free Trade Zone, Pudong New Area, Shanghai Patentee after: SHANGHAI ZEYUAN MARINE BIOTECHNOLOGY Co.,Ltd. Patentee after: JIAXING ZEYUAN BIOLOGICAL PRODUCTS Co.,Ltd. Address before: 678206 Huaxing Industrial Park, Youwang Town, Shidian County, Baoshan City, Yunnan Province Patentee before: Yunnan Baoshan Zeyuan algae industry health technology Co.,Ltd. |
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Effective date of registration: 20221209 Address after: 678206 Huaxing Industrial Park, Youwang Town, Shidian County, Baoshan City, Yunnan Province Patentee after: Yunnan Baoshan Zeyuan algae industry health technology Co.,Ltd. Address before: 201207 room 601ac-05, building 2, No. 351, GuoShouJing Road, pilot Free Trade Zone, Pudong New Area, Shanghai Patentee before: SHANGHAI ZEYUAN MARINE BIOTECHNOLOGY Co.,Ltd. Patentee before: JIAXING ZEYUAN BIOLOGICAL PRODUCTS Co.,Ltd. |
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| TR01 | Transfer of patent right | ||
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Address after: 678206 Huaxing Industrial Park, Youwang Town, Shidian County, Baoshan City, Yunnan Province Patentee after: Yunnan Baoshan Zeyuan algae industry health technology Co.,Ltd. Address before: 678206 Huaxing Industrial Park, Youwang Town, Shidian County, Baoshan City, Yunnan Province Patentee before: Yunnan Baoshan Zeyuan algae industry health technology Co.,Ltd. |
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