CN103543093B - 细胞测量设备 - Google Patents

细胞测量设备 Download PDF

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Publication number
CN103543093B
CN103543093B CN201310360814.1A CN201310360814A CN103543093B CN 103543093 B CN103543093 B CN 103543093B CN 201310360814 A CN201310360814 A CN 201310360814A CN 103543093 B CN103543093 B CN 103543093B
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passage
granule
measurement equipment
cell measurement
selectively
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CN103543093A (zh
Inventor
亚历山大·莱申斯基
阿维谢伊·布兰斯基
科琳·纳塔尼尔
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Technion Research and Development Foundation Ltd
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Technion Research and Development Foundation Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404Handling flow, e.g. hydrodynamic focusing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404Handling flow, e.g. hydrodynamic focusing
    • G01N15/1409Handling samples, e.g. injecting samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/0058Kind of property studied
    • G01N2203/0092Visco-elasticity, solidification, curing, cross-linking degree, vulcanisation or strength properties of semi-solid materials
    • G01N2203/0094Visco-elasticity

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201310360814.1A 2007-06-07 2008-06-05 细胞测量设备 Active CN103543093B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92499807P 2007-06-07 2007-06-07
US60/924,998 2007-06-07
CN2008801016866A CN101772697B (zh) 2007-06-07 2008-06-05 用于聚集颗粒的系统和方法

Related Parent Applications (1)

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CN2008801016866A Division CN101772697B (zh) 2007-06-07 2008-06-05 用于聚集颗粒的系统和方法

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CN103543093A CN103543093A (zh) 2014-01-29
CN103543093B true CN103543093B (zh) 2016-08-10

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CN201310360814.1A Active CN103543093B (zh) 2007-06-07 2008-06-05 细胞测量设备
CN2008801016866A Active CN101772697B (zh) 2007-06-07 2008-06-05 用于聚集颗粒的系统和方法

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US (2) US8642288B2 (https=)
EP (1) EP2153199B1 (https=)
JP (2) JP5337151B2 (https=)
CN (2) CN103543093B (https=)
WO (1) WO2008149365A2 (https=)

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KR102095617B1 (ko) 2013-03-15 2020-03-31 아이리스 인터내셔널 인크. 혈액 샘플에서의 입자 분석을 위한 오토포커스 시스템 및 방법
US9316635B2 (en) 2013-03-15 2016-04-19 Iris International, Inc. Sheath fluid systems and methods for particle analysis in blood samples
CN105705934B (zh) * 2013-09-03 2019-01-08 Izon科技有限公司 用于确定测量颗粒的电荷的方法和设备
WO2015116990A1 (en) * 2014-01-30 2015-08-06 The General Hospital Corporation Inertio-elastic focusing of particles in microchannels
EP2907574A1 (en) 2014-02-13 2015-08-19 OWL Biobedical, Inc. Microfluidic system with viscoelastic fluid
EP4115978A1 (en) 2015-01-14 2023-01-11 Pixcell Medical Technologies Ltd. Disposable cartridge for sample fluid analysis
WO2016165945A1 (en) * 2015-04-17 2016-10-20 Koninklijke Philips N.V. Dust processing
KR101855490B1 (ko) * 2016-01-22 2018-05-08 한국과학기술원 점탄성유체와 점성유체의 병행층류를 이용한 미소 입자 분리 및 세정 방법
JP6134402B1 (ja) * 2016-01-29 2017-05-24 シスメックス株式会社 生体試料撮像装置及び生体試料撮像方法
CN106248528A (zh) * 2016-09-27 2016-12-21 中国石油天然气股份有限公司 一种聚合物弹性强弱的评价方法
EP3631415B1 (en) * 2017-06-02 2026-03-25 The General Hospital Corporation Oscillatory focusing of particles in channels
CN108627448A (zh) * 2018-06-05 2018-10-09 江苏卓微生物科技有限公司 微粒计数的方法
US11185861B2 (en) 2018-06-13 2021-11-30 International Business Machines Corporation Multistage deterministic lateral displacement device for particle separation
EP4222276A1 (en) * 2020-09-29 2023-08-09 1087 Systems, Inc. Graded bioprocess monitoring and fluid self-modulation
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JP7152622B1 (ja) * 2022-03-30 2022-10-12 ポーラ化成工業株式会社 ウルトラファインバブルの気泡濃度測定方法

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CN1302229A (zh) * 1998-03-07 2001-07-04 斯蒂芬·C·沃德罗 用于进行血细胞计数的一次性设备
CN1582327A (zh) * 2001-09-06 2005-02-16 基因描绘系统有限公司 复制细胞的快速检测
CN101189271A (zh) * 2004-02-13 2008-05-28 北卡罗来纳大学查珀尔希尔分校 制造微流体设备的功能材料和新型方法

Also Published As

Publication number Publication date
WO2008149365A3 (en) 2009-03-05
JP5901582B2 (ja) 2016-04-13
WO2008149365A2 (en) 2008-12-11
CN101772697A (zh) 2010-07-07
JP5337151B2 (ja) 2013-11-06
US20100178666A1 (en) 2010-07-15
EP2153199A2 (en) 2010-02-17
US20140113358A1 (en) 2014-04-24
JP2013217946A (ja) 2013-10-24
EP2153199B1 (en) 2016-10-19
JP2010529452A (ja) 2010-08-26
CN103543093A (zh) 2014-01-29
CN101772697B (zh) 2013-08-21
US8642288B2 (en) 2014-02-04
US9470679B2 (en) 2016-10-18

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