IL148088A0 - Methods and apparatuses for stretching polymers - Google Patents
Methods and apparatuses for stretching polymersInfo
- Publication number
- IL148088A0 IL148088A0 IL14808800A IL14808800A IL148088A0 IL 148088 A0 IL148088 A0 IL 148088A0 IL 14808800 A IL14808800 A IL 14808800A IL 14808800 A IL14808800 A IL 14808800A IL 148088 A0 IL148088 A0 IL 148088A0
- Authority
- IL
- Israel
- Prior art keywords
- apparatuses
- methods
- stretching polymers
- stretching
- polymers
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
- B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
- B01F25/431—Straight mixing tubes with baffles or obstructions that do not cause substantial pressure drop; Baffles therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
- B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
- B01F25/432—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction with means for dividing the material flow into separate sub-flows and for repositioning and recombining these sub-flows; Cross-mixing, e.g. conducting the outer layer of the material nearer to the axis of the tube or vice-versa
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
- B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
- B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0663—Stretching or orienting elongated molecules or particles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0694—Creating chemical gradients in a fluid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0883—Serpentine channels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
- B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
- B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/44—Resins; rubber; leather
- G01N33/442—Resins, plastics
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Physics & Mathematics (AREA)
- Fluid Mechanics (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14902099P | 1999-08-13 | 1999-08-13 | |
PCT/US2000/022253 WO2001013088A1 (en) | 1999-08-13 | 2000-08-11 | Methods and apparatuses for stretching polymers |
Publications (1)
Publication Number | Publication Date |
---|---|
IL148088A0 true IL148088A0 (en) | 2002-09-12 |
Family
ID=22528446
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14808800A IL148088A0 (en) | 1999-08-13 | 2000-08-11 | Methods and apparatuses for stretching polymers |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1210578A4 (en) |
JP (1) | JP2003507026A (en) |
CN (1) | CN1379857A (en) |
AU (1) | AU6771100A (en) |
CA (1) | CA2381361A1 (en) |
IL (1) | IL148088A0 (en) |
WO (1) | WO2001013088A1 (en) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7056661B2 (en) | 1999-05-19 | 2006-06-06 | Cornell Research Foundation, Inc. | Method for sequencing nucleic acid molecules |
US6927065B2 (en) | 1999-08-13 | 2005-08-09 | U.S. Genomics, Inc. | Methods and apparatus for characterization of single polymers |
US7211414B2 (en) | 2000-12-01 | 2007-05-01 | Visigen Biotechnologies, Inc. | Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity |
EP2801624B1 (en) | 2001-03-16 | 2019-03-06 | Singular Bio, Inc | Arrays and methods of use |
US8423294B2 (en) | 2001-09-18 | 2013-04-16 | Pathogenetix, Inc. | High resolution linear analysis of polymers |
GB0125436D0 (en) * | 2001-10-23 | 2001-12-12 | Deltadot Ltd | Analysis of temperature-dependent molecular configurations |
WO2003106693A2 (en) | 2002-01-01 | 2003-12-24 | Princeton University | Gradient structures interfacing microfluidics and nanofluidics, methods for fabrication and uses thereof |
US7282330B2 (en) | 2002-05-28 | 2007-10-16 | U.S. Genomics, Inc. | Methods and apparati using single polymer analysis |
JP2005527220A (en) | 2002-05-28 | 2005-09-15 | ユー.エス. ジェノミクス, インコーポレイテッド | Method and apparatus using single polymer analysis |
JP2005533256A (en) * | 2002-07-17 | 2005-11-04 | ユー.エス. ジェノミクス, インコーポレイテッド | Methods and compositions for analyzing polymers using chimeric tags |
WO2004091795A2 (en) * | 2003-04-10 | 2004-10-28 | U.S. Genomics, Inc. | Manipulation of polymers in a microchannel |
JP4215054B2 (en) * | 2003-09-02 | 2009-01-28 | 日本電気株式会社 | Biomolecule analysis method and biomolecule identification method using the same |
JP2007518107A (en) | 2004-01-13 | 2007-07-05 | ユー.エス. ジェノミクス, インコーポレイテッド | Detection and quantification of analytes in solution using polymers |
US7595160B2 (en) | 2004-01-13 | 2009-09-29 | U.S. Genomics, Inc. | Analyte detection using barcoded polymers |
CN101151377B (en) * | 2004-05-13 | 2015-04-01 | 纳米生物技术股份有限公司 | Nano-PCR: methods and devices for nucleic acid amplification and detection |
KR101506727B1 (en) * | 2004-05-13 | 2015-04-03 | 나노바이오심 인크. | Nano-PCR: Methods and devices for nucleic acid amplification and detection |
US7170050B2 (en) | 2004-09-17 | 2007-01-30 | Pacific Biosciences Of California, Inc. | Apparatus and methods for optical analysis of molecules |
WO2007076132A2 (en) * | 2005-12-23 | 2007-07-05 | Nanostring Technologies, Inc. | Compositions comprising oriented, immobilized macromolecules and methods for their preparation |
EP2016415B1 (en) | 2006-04-21 | 2013-08-14 | Nanobiosym, Inc. | Single-molecule platform for drug discovery: methods for drug discovery, including discovery of anticancer and antiviral agents |
US7312029B1 (en) | 2006-06-30 | 2007-12-25 | Searete Llc | Method of combing an elongated molecule |
SG173398A1 (en) * | 2006-07-19 | 2011-08-29 | Bionanomatrix Inc | Nanonozzle device arrays: their preparation and use for macromolecular analysis |
JP5086335B2 (en) * | 2007-03-02 | 2012-11-28 | 株式会社セイシン企業 | Flow cell and particle shape analyzer equipped with the same |
CN101765462B (en) * | 2007-03-28 | 2013-06-05 | 博纳基因技术有限公司 | Methods of macromolecular analysis using nanochannel arrays |
JP5337151B2 (en) * | 2007-06-07 | 2013-11-06 | テクニオン リサーチ アンド ディベロップメント ファウンデーション リミテッド | System and method for focusing particles |
US8367424B2 (en) | 2007-10-15 | 2013-02-05 | Rohm Co., Ltd. | Microchip and method of using the same |
CN102084001B (en) | 2008-03-28 | 2015-03-18 | 加利福尼亚太平洋生物科学股份有限公司 | Compositions and methods for nucleic acid sequencing |
KR20170094003A (en) | 2008-06-06 | 2017-08-16 | 바이오나노 제노믹스, 인크. | Integrated nanofluidic analysis devices, fabrication methods and analysis techniques |
CN102292451A (en) | 2008-06-30 | 2011-12-21 | 生物纳米芯股份有限公司 | Methods and devices for single-molecule whole genome analysis |
CN102292454B (en) | 2008-11-18 | 2014-11-26 | 博纳基因技术有限公司 | Polynucleotide mapping and sequencing |
WO2011108540A1 (en) | 2010-03-03 | 2011-09-09 | 国立大学法人大阪大学 | Method and device for identifying nucleotide, and method and device for determining nucleotide sequence of polynucleotide |
GB201111237D0 (en) * | 2011-06-30 | 2011-08-17 | Isis Innovation | Nanochip |
WO2013039778A2 (en) | 2011-09-12 | 2013-03-21 | The University Of North Carolina At Chapel Hill | Devices with a fluid transport nanochannel intersected by a fluid sensing nanochannel and related methods |
EP2570488A1 (en) * | 2011-09-16 | 2013-03-20 | Centre National de la Recherche Scientifique (C.N.R.S) | Method for longitudinal macromolecule spreading and method for analyzing macromolecules |
US9989515B2 (en) | 2012-02-10 | 2018-06-05 | The University Of North Carolina At Chapel Hill | Devices with fluidic nanofunnels, associated methods, fabrication and analysis systems |
CN104272089B (en) * | 2012-03-05 | 2017-05-10 | 松下知识产权经营株式会社 | Sensor device |
EP2872652A4 (en) * | 2012-04-18 | 2016-03-09 | Pathogenetix Inc | Devices and methods for nucleic acid preparation and analysis |
EP2887058B1 (en) | 2012-08-17 | 2017-11-29 | Quantum Biosystems Inc. | Sample analysis method |
US10261065B2 (en) | 2013-02-28 | 2019-04-16 | The University Of North Carolina At Chapel Hill | Nanofluidic devices with integrated components for the controlled capture, trapping, and transport of macromolecules and related methods of analysis |
JP2014173934A (en) * | 2013-03-07 | 2014-09-22 | Toshiba Corp | Semiconductor micro-analysis chip and manufacturing method thereof |
CN105452482B (en) | 2013-03-13 | 2020-03-06 | 北卡罗来纳-查佩尔山大学 | Nanofluidic devices for rapid mapping of whole genomes and related analysis systems and methods |
US10933417B2 (en) | 2013-03-15 | 2021-03-02 | Nanobiosym, Inc. | Systems and methods for mobile device analysis of nucleic acids and proteins |
CN104368250B (en) * | 2013-08-13 | 2017-12-22 | 北京慧荣和科技有限公司 | Gas or aerosol mixing or dilution device |
KR20160079780A (en) | 2013-09-18 | 2016-07-06 | 퀀텀 바이오시스템즈 가부시키가이샤 | Biomolecule sequencing devices, systems and methods |
JP2015077652A (en) | 2013-10-16 | 2015-04-23 | クオンタムバイオシステムズ株式会社 | Nano-gap electrode and method for manufacturing same |
CN106414767A (en) * | 2014-01-24 | 2017-02-15 | 量子生物有限公司 | Devices, systems and methods for sequencing biomolecules |
US10438811B1 (en) | 2014-04-15 | 2019-10-08 | Quantum Biosystems Inc. | Methods for forming nano-gap electrodes for use in nanosensors |
WO2015170782A1 (en) * | 2014-05-08 | 2015-11-12 | Osaka University | Devices, systems and methods for linearization of polymers |
US10471428B2 (en) | 2015-05-11 | 2019-11-12 | The University Of North Carolina At Chapel Hill | Fluidic devices with nanoscale manifolds for molecular transport, related systems and methods of analysis |
GB2608517B (en) | 2017-11-30 | 2023-03-29 | Axalta Coating Systems Gmbh | Coating compositions for application utilizing a high transfer efficiency applicator and methods and systems thereof |
US20220062837A1 (en) * | 2018-12-21 | 2022-03-03 | Nanorial Technologies Ltd. | Apparatus, methods, and systems for mixing, dispersing substances |
CN112473418B (en) * | 2020-11-06 | 2021-07-02 | 中国石油大学(北京) | Super-dry carbon dioxide foam generating device for continuous oil pipe and application thereof |
CN113617402A (en) * | 2021-07-07 | 2021-11-09 | 福建农林大学 | Microfluidic chip and device for generating shearing and stretching combined flow field and application method thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3123249B2 (en) * | 1991-09-10 | 2001-01-09 | 株式会社日立製作所 | DNA molecule length measuring method and measuring device |
US5538898A (en) * | 1995-03-16 | 1996-07-23 | International Business Machines Corporation | Method suitable for identifying a code sequence of a biomolecule |
US5846832A (en) * | 1995-09-20 | 1998-12-08 | The Board Of Trustees Of The Leland Stanford Junior University | Apparatus and method for shear breakage of polynucleotides |
WO1999009042A2 (en) * | 1997-08-13 | 1999-02-25 | Cepheid | Microstructures for the manipulation of fluid samples |
CA2340228A1 (en) * | 1998-08-13 | 2000-02-24 | U.S. Genomics, Inc. | Optically characterizing polymers |
-
2000
- 2000-08-11 WO PCT/US2000/022253 patent/WO2001013088A1/en active Application Filing
- 2000-08-11 IL IL14808800A patent/IL148088A0/en unknown
- 2000-08-11 CA CA002381361A patent/CA2381361A1/en not_active Abandoned
- 2000-08-11 JP JP2001517140A patent/JP2003507026A/en active Pending
- 2000-08-11 CN CN00814266A patent/CN1379857A/en active Pending
- 2000-08-11 AU AU67711/00A patent/AU6771100A/en not_active Abandoned
- 2000-08-11 EP EP00955515A patent/EP1210578A4/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
AU6771100A (en) | 2001-03-13 |
WO2001013088A1 (en) | 2001-02-22 |
EP1210578A1 (en) | 2002-06-05 |
CA2381361A1 (en) | 2001-02-22 |
JP2003507026A (en) | 2003-02-25 |
EP1210578A4 (en) | 2007-02-21 |
CN1379857A (en) | 2002-11-13 |
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