CN103462844A - Hair-care composition containing efficient anti-hair-loss compound agent - Google Patents
Hair-care composition containing efficient anti-hair-loss compound agent Download PDFInfo
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Abstract
The invention relates to a hair-care composition containing an efficient anti-hair-loss compound agent. The hair-care composition comprises long-chain alcohol, a cationic surface active agent, a thickening agent, essence, a preservative, a chelating agent, water and an anti-hair-loss compound active matter, wherein the anti-hair-loss compound active matter accounts for 0.1 to 10 percent of weight of the composition and is a composition of hydrolyzed soy protein, amino acid, amino sugar, vitamin B complex, zinc salt, ginseng essence, May burdock root essence, organic silicon and polyquaternium. By virtue of the hair-care composition, the hair growth can be promoted, the ratio of a growing period to a resting period of hair is improved, forming of healthy scalp and healthy hair is promoted, and the hair loss speed of a hair loss patient is returned to be normal.
Description
Technical field
The present invention relates to a kind of Haircare composition.Be particularly related to a kind of Haircare composition containing efficient anticreep complexing agent.
Background technology
Hair has multi-functional to the people, mechanicalness protection effect, anti-ultraviolet effect, regulate body temperature effect, sense of touch effect and social effect.Now increasing people becomes the person of catching cold of alopecia, and the alopecia meeting affects people's profile, reduces captivation and glamour, causes serious problem at heart, and reduces self-confidence.At human body, the growth of hair and replacement are not successive, but are periodic.Hair derives from the bottom of hair follicle, and hair follicle demonstrates periodic activity, forms the periodicity of natural on-off cycles of hair growth.The growth circulation of hair can be divided into three phases, i.e. trophophase, catagen and resting stage.Hair in trophophase is the growth state that enlivens, and ball top bottom cell division is accelerated, and ball top top cell differentiation is cortex, hair cuticle; Hair papilla increases, cell division is accelerated, and number increases, during this hair increase 0.27-0.4mm. every day and enter catagen after the positive hypertrophy of hair stop, form club hair, internal root sheath disappears, and external root sheath is keratinization gradually, and ball top flattens, be not in depression, hair papilla is set up and to be dwindled, and cell number reduces, and hair no longer increases and becomes loosening and is easy to come off.During resting stage, the keratinization of Rhizoma Imperatae section is downward gradually, with hair papilla, separates, and separation place hair follicle shrinks, alopecia.Then, new hair papilla forms gradually, and hair is the repeated growth cycle again.Hair in trophophase and resting stage constantly keeps dynamic equilibrium, normally maintains 100 of every day with interior alopecia, once this balance is broken ring, hair just there will be the alopecia phenomenon.The purpose of this invention is to provide a kind of hair conditioner composition, add and a kind ofly derive from plant and biochemical synthetic there is synergistic anti-alopecia complex, make the cytotrophy of ball top section improve, cytoactive strengthens, division is accelerated, maintain the dynamic equilibrium of natural on-off cycles of hair growth phase and resting stage, make the spontaneous growth cycle of hair return to naturalness, safeguard the health of hair.
Summary of the invention
The purpose of this invention is to provide a kind of Haircare composition with efficient anticreep effect.
Haircare composition of the present invention, except essence, antiseptic, chelating agen, water, include
(A) account for the long-chain alcohol of saturated straight or branched of 8 to 22 carbon atoms of the 1%-20% of composition weight;
(B) account for the 0.1%-10% cationic surfactant of composition weight;
(C) account for the thickening agent of the 0.05%-3% of composition weight;
(D) account for the anticreep composite reactive thing of composition weight 0.1% to 10%; Described anticreep composite reactive thing is, outside dewatering, to contain:
Account for the Radix Ginseng essence of composite reactive thing weight 10-25%;
Account for the hydrolyzed soybean protein of composite reactive thing weight 1-5%;
Account for the ispol of composite reactive thing weight 4-20%, this ispol is mixed with the ratio of weight ratio 1 ︰ 1 ︰ 1 ︰ 1 by Jing An Suan ︰ acetyl network An Suan ︰ Gua An Suan ︰ dlornithine hydrochloride;
Account for the vitamin B group mixture of composite reactive thing weight 3-10%, this vitamin B group mixture is mixed with the ratio of weight ratio 1 ︰ 1 ︰ 1 by vitamin B 3 ︰ vitamin B 5 ︰ biotins;
Account for the glucosamine hydrochloride of composite reactive thing weight 5-10%;
Account for the zinc gluconate of composite reactive thing weight 1-5%;
Account for the Radix Arctii essence in May of composite reactive thing weight 1-5%;
Account for the PEG-12 dimethicone of composite reactive thing weight 1-5%
Account for the polyquaternary ammonium salt-11 of composite reactive thing weight 1-5%.
Haircare composition of the present invention, described long-chain alcohol is selected from least one in tetradecyl alchohol, hexadecanol, octadecanol, eicosanol, docosanol, isooctadecanol, octyl group glycol and oleyl alcohol.
Haircare composition of the present invention, its cationic surfactant be selected from PEG-2 olein ylmethyl ammonium chloride,, cocoyl trimethyl ammonium chloride, hexadecyltrimethylammonium chloride, stearyl trimethyl ammonium chloride, mountain Yu base trimethyl ammonium chloride, two stearyl alkyl dimethyl ammonium chloride, stearamide propyl dimethylamine at least one.
Haircare composition of the present invention, its thickening agent is selected from least one of hydroxyethyl-cellulose, hydroxypropyl emthylcellulose, hydroxy methocel, hydroxyethyl ethylcellulose.
Compared with prior art, the present invention has the following advantages:
With conventional Haircare composition, compare, wherein added appropriate anticreep composite reactive thing, its anticreep composite reactive thing is hydrolyzed soybean protein, ispol containing arginine, acetyl TYR, citrulline, dlornithine hydrochloride, glucosamine hydrochloride, containing the vitamin B group mixture of vitamin B3, vitamin B5, biotin, zinc gluconate, the Radix Ginseng essence, May Radix Arctii essence and PEG-12 dimethicone and polyquaternary ammonium salt-11 compositions.Adding of described vegetalitas and biochemical synthetic, can help the patient to recover the normal ratio of natural on-off cycles of hair growth phase and resting stage, alleviates alopecia, promotes to form healthy hair and scalp, helps alopecia person to return to normal alopecia speed.
The specific embodiment
The material of below the present invention being selected is described in further detail.
Haircare composition of the present invention, its content of described long-chain alcohol accounts for the 1%-20% of composition levels, and preferred content is 3-8%.Its long-chain alcohol is the mixed alcohol of hexadecanol and octadecanol preferably, and more preferably the ratio of hexadecanol and octadecanol is classified the mixed alcohol of 3:7 as, and its structural formula is CH
2(CH
2)
14cH
2oH (hexadecanol) and CH
2(CH
2)
16cH
2the OH(octadecanol), outward appearance is white plates, and acid number is≤0.1mgKOH/g that iodine number is≤0.5I
2g/100g, saponification number is≤1.0mgKOH/g, and hydroxyl value is 210-220mgKOH/g, and fusing point is 50-55 ℃.
Haircare composition of the present invention, its content of described cationic surfactant accounts for the 0.1%-10% of composition levels, and preferred content is 0.5-5%.Cationic surfactant is mountain Yu base trimethyl ammonium chloride preferably, and its outward appearance is extremely micro-yellow solid of white, active matter content 74%-84%, and unhindered amina≤1.2%, pH value (1.% solution of 1:1 ethanol and water) is 5.0-8.0.
Haircare composition of the present invention, its content of described thickening agent accounts for the 0.05%-3% of composition levels, and preferred content is 0.1-1%.Thickening agent is hydroxyethyl-cellulose preferably.Its outward appearance be white to light brown powder, pH value (25 ℃, 2% aqueous solution) is 5.5-8.5, viscosity (25 ℃, 1% aqueous solution) is 3400-5500cps.
Haircare composition of the present invention can also comprise many optional components, comprises chelating agen, pH adjusting agent, antiseptic, essence, pigment.Described chelating agen accounts for 0.01% to 0.30% of composition weight, and the non-limiting example of described chelating agen has: ethylenediaminetetraacetic acid, disodiumedetate, tetrasodium ethylenediamine tetraacetate etc., preferably disodiumedetate; The non-limiting example of described pH adjusting agent has: citric acid, phosphoric acid, lactic acid etc., and optimization citric acid, the pH of regulation system is 4.0 to 8.5, and preferably 4.0 to 5.5; ; Choosing of described antiseptic, essence, pigment, meet the regulation of hygienic standards for cosmetics, selects safe raw material.
Contain appropriate anticreep composite reactive thing in Haircare composition of the present invention, comprise hydrolyzed soybean protein, ispol containing arginine, acetyl TYR, citrulline, dlornithine hydrochloride, glucosamine hydrochloride, vitamin B group mixture containing vitamin B3, vitamin B5, biotin, zinc gluconate, the Radix Ginseng essence, May Radix Arctii essence and PEG-12 dimethicone and polyquaternary ammonium salt-11.Its content accounts for 0.1% to 10% of composition weight, preferred content 5% to 10%.Described anticreep composite reactive thing is limpid light yellow liquid, and with special odor, under 20 ℃ of conditions, its density is 1.010-1.050, and index of refraction is 1.350-1.360, and pH value is 5.2-6.2.
Contain appropriate anticreep composite reactive thing in Haircare composition of the present invention, the composition that it is concrete and active as follows: hydrolyzed soybean protein (hydrolyzed soy sulfuration peptide, MW-15000Da) be a kind of full-natural nutritive material extracted from Semen sojae atricolor, it is the important component part of human body cell, it can provide the required nutrition of ball top bottom cell and regulate Growth of Cells, promotes the biosynthesis of albumen; Aminoacid is the mixture of arginine, acetyl TYR, citrulline, dlornithine hydrochloride, TYR is polarity neutral aminoacid, the aminoacid that arginine, citrulline, ornithine are the polarity zone positive charge, these several ispols are hair and scalp nutrient protein and melanic precursor, can significantly penetrate into hair cortex, effectively suppress free radical, prevent the effect that free radical is propagated, the enemy is initiated to protective effect; Amino sugar is glucosamine, can strengthen hair papilla and substrate on every side thereof; The vitamin B group comprises vitamin B3, vitamin B5 and biotin, can regulate cytotrophy, is beneficial to the cell be hurt and restores, and promotes cell regeneration, promotes the scalp metabolism, improves the scalp health state, prevents alopecia; Zinc salt is zinc gluconate, can prevent more fat secretion, regulates the oils and fats balance; The Radix Ginseng essence and May the Radix Arctii essence containing multiple Saponin and polysaccharide composition, can slowly be absorbed by scalp, blood circulation promoting, increase scalp nutrition, regulate water oil balance, can make the telangiectasis of scalp, increase the nutrition of hair, improve the toughness of hair, reduce alopecia, disconnectedly send out, the hair of damage is had to protective effect; Organosilicon and polyquaternary ammonium salt provide the opsonic action of hair.
Preparation method
The Haircare composition that comprises efficient anticreep complexing agent of the present invention can by any known or other effectively be applicable to provide the technology preparation of Haircare composition, prepare the method containing efficient anticreep complexing agent Haircare composition of the present invention and comprise conventional preparation and hybrid technology.
Using method
The Haircare composition that comprises efficient anticreep complexing agent of the present invention is used in clean and mode conditioning hair of routine, mainly comprises following step:
(A) clean hair with appropriate shampoo;
(B) use the Haircare composition of the aforementioned any one claim of effective dose on described hair, keep 1-3 minute, the scope of described effective dose is generally 1 gram to 50 gram, preferably 3 to 20 grams;
(C) make hair conditioner can rest on 3-5 minute on hair, and carry out soft scalp massage;
(D) with the Haircare composition on the described hair of water rinse.
These steps can be as required repeatedly, to reach the nursing effect of looking for.
Embodiment
It is below the non-limiting example of the Haircare composition that comprises efficient anticreep complexing agent of the present invention.Providing of these embodiment is only for illustrative purposes, can not be interpreted as limitation of the invention, because without departing from the spirit and scope of the present invention, can carry out many changes to the present invention.In these embodiments, unless stated otherwise, all concentration is all percentage by weight.Term used " a small amount of material " refers to those optional materials, and as antiseptic, pH adjusting agent, spice, pigment etc., the selection of these a small amount of materials will be along with selected changing in order to the physics and chemistry characteristic for preparing special component of the present invention.
Preparation Example I-X
The method of the Haircare composition that comprises efficient anticreep complexing agent described in suitable Preparation Example I-X is as follows:
Suitable quantity of water is joined in retort, add hydroxyethyl-cellulose to disperse, stir 5 minutes, add mountain Yu base trimethyl ammonium chloride, be warming up to 80 ℃, add 16/octadecanol, disodiumedetate, methyl hydroxybenzoate, propylparaben (if using these materials), be warming up to 80 ℃ and mix homogeneously, after all material dissolutions with 2500rmp/min homogenizing 1 minute and 30 seconds, then be evacuated to-0.02Mpa, homogenizing finishes cooling, mixing speed is adjusted to 30～35rpm/min, be evacuated to minimum, add anticreep composite reactive thing, citric acid, antiseptic, essence, pigments etc. continue to stir, guarantee to obtain uniform mixture.
Embodiment I-V
Embodiment VI-X
Embodiment XI-X V
In above-described embodiment I-X V, outside dewatering in anticreep composite reactive thing, containing 21% Radix Ginseng essence, 5% hydrolyzed soybean protein, 14% ispol (Jing An Suan ︰ acetyl network An Suan ︰ Gua An Suan ︰ dlornithine hydrochloride=1 ︰ 1 ︰ 1 ︰ 1), 7.5% vitamin B group mixture (vitamin B 3 ︰ vitamin B 5 ︰ biotins=1 ︰ 1 ︰ 1), 7% glucosamine hydrochloride, 3% zinc gluconate, 3.5% May Radix Arctii essence and 2%PEG-12 dimethicone and 1.5% polyquaternary ammonium salt-11, each constituent content is weight percentage.
The sense organ physical and chemical index
The checking of Anti-hair loss effect
Method of testing: select 60 volunteers that alopecia is arranged, require without allergy, without the scalp health patient of wound, unsystematic local disease, by image viewing, the trophophase of its patient's hair and the ratio of resting stage are lower than normal condition.The patient is divided into to 3 groups at random, uses respectively embodiment of the present invention IV, VIII, X III hair conditioner, continue to use 120 days, before use, use 60 days and use and within 120 days, carry out sensory evaluation and hair image evaluation.In process on probation, the volunteer is according to normally using at ordinary times the hair conditioner frequency to use this hair conditioner, requires this hair conditioner can rest on hair 3-5 minute and carry out soft scalp massage, and then clean with warm water washing.For the sensory evaluation who uses volunteer before and after this hair conditioner to reduce hair in Table 1, table 2, table 3 and hair image evaluation be in Table 4:
Table 1
Table 2
Table 3
Table 4
Claims (4)
1. the Haircare composition containing efficient anticreep complexing agent, except essence, antiseptic, chelating agen, water, include
(A) account for the long-chain alcohol of 8 to 22 straight or brancheds that carbon atom is saturated of composition weight 1%-20%;
(B) account for the cationic surfactant of composition weight 0.1%-10%;
(C) account for the thickening agent of composition weight 0.05%-3%;
(D) account for the anticreep composite reactive thing of composition weight 0.1% to 10%; This anticreep composite reactive thing is composed of the following components:
Account for the Radix Ginseng essence of composite reactive thing weight 10-25%;
Account for the hydrolyzed soybean protein of composite reactive thing weight 1-5%;
Account for the ispol of composite reactive thing weight 4-20%, this ispol is mixed with the ratio of weight ratio 1 ︰ 1 ︰ 1 ︰ 1 by Jing An Suan ︰ acetyl network An Suan ︰ Gua An Suan ︰ dlornithine hydrochloride;
Account for the vitamin B group mixture of composite reactive thing weight 3-10%, this vitamin B group mixture is mixed with the ratio of weight ratio 1 ︰ 1 ︰ 1 by vitamin B 3 ︰ vitamin B 5 ︰ biotins;
Account for the glucosamine hydrochloride of composite reactive thing weight 5-10%;
Account for the zinc gluconate of composite reactive thing weight 1-5%;
Account for the Radix Arctii essence in May of composite reactive thing weight 1-5%;
Account for the PEG-12 dimethicone of composite reactive thing weight 1-5%;
Account for the polyquaternary ammonium salt-11 of composite reactive thing weight 1-5%;
And the water of surplus.
2. Haircare composition according to claim 1, described long-chain alcohol is selected from least one in tetradecyl alchohol, hexadecanol, octadecanol, eicosanol, docosanol, isooctadecanol, octyl group glycol and oleyl alcohol.
3. Haircare composition according to claim 1 and 2, wherein cationic surfactant be selected from PEG-2 olein ylmethyl ammonium chloride,, cocoyl trimethyl ammonium chloride, hexadecyltrimethylammonium chloride, stearyl trimethyl ammonium chloride, mountain Yu base trimethyl ammonium chloride, two stearyl alkyl dimethyl ammonium chloride, stearamide propyl dimethylamine at least one.
4. Haircare composition according to claim 1 and 2, wherein thickening agent is selected from least one of hydroxyethyl-cellulose, hydroxypropyl emthylcellulose, hydroxy methocel, hydroxyethyl ethylcellulose.
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Cited By (14)
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| CN103866569A (en) * | 2014-04-01 | 2014-06-18 | 许昌恒源发制品股份有限公司 | Hair stiffening agent as well as preparation method and application method thereof |
| CN104274359A (en) * | 2014-09-05 | 2015-01-14 | 拉芳家化股份有限公司 | Hair care composition containing paramela plant essential oil |
| CN104546548A (en) * | 2014-12-31 | 2015-04-29 | 陈扬 | Translucent silicone-free hair care composition and method for preparing hair care composition |
| CN104814884A (en) * | 2015-04-21 | 2015-08-05 | 山东福瑞达生物科技有限公司 | Liquid shampoo capable of preventing hair loss and promoting hair growth and preparation method thereof |
| CN105213224A (en) * | 2015-09-22 | 2016-01-06 | 拉芳家化股份有限公司 | A kind of Haircare composition of moisturizing |
| CN105520870A (en) * | 2015-11-26 | 2016-04-27 | 澳宝化妆品（惠州）有限公司 | Hair caring composition containing pea sprout extract |
| CN106265347A (en) * | 2016-09-19 | 2017-01-04 | 拉芳家化股份有限公司 | A kind of Haircare composition based on marine bioactivity thing and application thereof |
| CN106491482A (en) * | 2016-10-08 | 2017-03-15 | 拉芳家化股份有限公司 | A kind of Haircare composition containing aging resistance and anticreep complexing agent |
| CN108324591A (en) * | 2018-02-13 | 2018-07-27 | 佛山市安安美容保健品有限公司 | A kind of hair composition containing marine bioactivity object |
| CN109498499A (en) * | 2018-11-26 | 2019-03-22 | 澳宝化妆品（惠州）有限公司 | A kind of composition for maintenance hair scalp before having one's hair wash |
| CN109908051A (en) * | 2019-03-14 | 2019-06-21 | 广州德谷个人护理用品有限公司 | A kind of ginseng nature hair conditioner and preparation method thereof |
| CN110711155A (en) * | 2019-11-20 | 2020-01-21 | 吉林禾未来功能产品有限公司 | Ginseng hair conditioner for repairing damaged hair and preparation method thereof |
| CN111117583A (en) * | 2018-10-31 | 2020-05-08 | 中国石油天然气股份有限公司 | Fracturing diverting agent and preparation method thereof |
| CN112494532A (en) * | 2020-12-17 | 2021-03-16 | 弘美制药（中国）有限公司 | Composition for preventing hair loss and nourishing scalp, preparation method and application thereof |
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| CN103866569A (en) * | 2014-04-01 | 2014-06-18 | 许昌恒源发制品股份有限公司 | Hair stiffening agent as well as preparation method and application method thereof |
| CN103866569B (en) * | 2014-04-01 | 2016-03-02 | 许昌恒源发制品股份有限公司 | Hair stiffening agent and preparation method thereof and using method |
| CN104274359B (en) * | 2014-09-05 | 2017-07-18 | 拉芳家化股份有限公司 | A kind of Haircare composition containing handkerchief Yago Lamela essential oil |
| CN104274359A (en) * | 2014-09-05 | 2015-01-14 | 拉芳家化股份有限公司 | Hair care composition containing paramela plant essential oil |
| CN104546548A (en) * | 2014-12-31 | 2015-04-29 | 陈扬 | Translucent silicone-free hair care composition and method for preparing hair care composition |
| CN104546548B (en) * | 2014-12-31 | 2017-12-01 | 陈扬 | One kind is without translucent Haircare composition of silicone oil and preparation method thereof |
| CN104814884B (en) * | 2015-04-21 | 2017-09-01 | 山东福瑞达生物科技有限公司 | A kind of pre-Anti-hair loss and trichogenous shampoo and preparation method thereof |
| CN104814884A (en) * | 2015-04-21 | 2015-08-05 | 山东福瑞达生物科技有限公司 | Liquid shampoo capable of preventing hair loss and promoting hair growth and preparation method thereof |
| CN105213224A (en) * | 2015-09-22 | 2016-01-06 | 拉芳家化股份有限公司 | A kind of Haircare composition of moisturizing |
| CN105520870A (en) * | 2015-11-26 | 2016-04-27 | 澳宝化妆品（惠州）有限公司 | Hair caring composition containing pea sprout extract |
| CN106265347A (en) * | 2016-09-19 | 2017-01-04 | 拉芳家化股份有限公司 | A kind of Haircare composition based on marine bioactivity thing and application thereof |
| CN106491482A (en) * | 2016-10-08 | 2017-03-15 | 拉芳家化股份有限公司 | A kind of Haircare composition containing aging resistance and anticreep complexing agent |
| CN108324591A (en) * | 2018-02-13 | 2018-07-27 | 佛山市安安美容保健品有限公司 | A kind of hair composition containing marine bioactivity object |
| CN108324591B (en) * | 2018-02-13 | 2021-03-30 | 佛山市安安美容保健品有限公司 | A hair composition containing marine bioactive substances |
| CN111117583A (en) * | 2018-10-31 | 2020-05-08 | 中国石油天然气股份有限公司 | Fracturing diverting agent and preparation method thereof |
| CN111117583B (en) * | 2018-10-31 | 2022-02-01 | 中国石油天然气股份有限公司 | Fracturing diverting agent and preparation method thereof |
| CN109498499A (en) * | 2018-11-26 | 2019-03-22 | 澳宝化妆品（惠州）有限公司 | A kind of composition for maintenance hair scalp before having one's hair wash |
| CN109498499B (en) * | 2018-11-26 | 2022-01-28 | 澳宝化妆品（惠州）有限公司 | Composition for caring hair and scalp before washing hair |
| CN109908051A (en) * | 2019-03-14 | 2019-06-21 | 广州德谷个人护理用品有限公司 | A kind of ginseng nature hair conditioner and preparation method thereof |
| CN110711155A (en) * | 2019-11-20 | 2020-01-21 | 吉林禾未来功能产品有限公司 | Ginseng hair conditioner for repairing damaged hair and preparation method thereof |
| CN112494532A (en) * | 2020-12-17 | 2021-03-16 | 弘美制药（中国）有限公司 | Composition for preventing hair loss and nourishing scalp, preparation method and application thereof |
| CN112494532B (en) * | 2020-12-17 | 2022-05-31 | 弘美制药（中国）有限公司 | Composition for preventing hair loss and nourishing scalp as well as preparation method and application thereof |
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