CN103372178A - Medicament and preparation method thereof - Google Patents
Medicament and preparation method thereof Download PDFInfo
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- CN103372178A CN103372178A CN2012101069274A CN201210106927A CN103372178A CN 103372178 A CN103372178 A CN 103372178A CN 2012101069274 A CN2012101069274 A CN 2012101069274A CN 201210106927 A CN201210106927 A CN 201210106927A CN 103372178 A CN103372178 A CN 103372178A
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Abstract
The invention relates to the field of health products, and discloses a medicament. The medicament comprises main components of natural precious herbs such as morinda officinalis, herba cistanche, gastrodia elata, eucommia ulmoides, polygonum multiflorum, saffron crocus, medlar, angelica sinensis, rhizoma polygonati, pseudo-ginseng, lucid ganoderma, ginseng and the like. The invention also discloses the content of each component. The medicament comprises a plurality of effective ingredients of panaxoside, panaxadiol saponin and the like, has the functions of improving blood microcirculation, relieving and balancing cranial nerve, smoothing lymph to expel toxin, and promoting metabolism, contains starch, protein, fat, tannin, flavonoids compounds, phenolic compound and trace volatile oil, and also contains microelements iron, zinc and the like with biological activity; the leaf and stem contain a little of alkaloid, which has the functions of whitening the skin, resisting fatigue and caducity, improving mental sleep, physical power and function, and the like. The invention also discloses a preparation method of the medicament disclosed by the invention. The method comprises the steps of selecting materials, cleaning, fertilizing, drying and mechanically crushing. The process is advanced and unique; the dosage form can be changed; any other chemical reagent is not added; the medicament is environment-friendly.
Description
Technical field
The present invention and health preserving product scope disclose a kind of medicine and preparation method thereof.
Background technology
Along with socioeconomic development, people's consumption idea is also changing step by step, and people are also higher to the expected value of daily life, and this is mainly reflected in the develop rapidly of health preserving product etc. industry.
Before 5000, ancient Chinese have just found herbal health preserving effect, initial 3000, it is for maintaining healthy rather than treatment disease that people take herbal purpose mostly, people's health status can be improved and promote to the edible correct herbaceous plant that makes up of accumulating over a long period, and the autoimmunity resistance is improved greatly.The health of foot can systemic health.Clinical medicine is found, fatty liver, diabetes, gynaecopathia, hypertension, cerebral thrombosis, heart disease, prostatosis, gout, insomnia, arthritis, hyperosteogeny diseases all can be cold and cool from foot the earliest, and numbness is ached, swelling is knotted, and the discomforts such as pain reflect, long-run development local disease will develop into chronic whole body severe disease, shows that through investigation 40%～50% disease is that microcirculation is obstructed, and 60～70% subhealth states are that the organismic internal environment endotoxin is accumulated and caused.Learn from collaterals of human, the vital organs of the human body have corresponding echo area on foot, foot is not only the starting point of Three Yin Channels of Foot, or the termination of the three yang channels of foots, hallux toe is communicated with the liver spleen channel, and the 4th apotelus leads to gallbladder meridian, little toe ownership urinary bladder channel, kidney channel place vola section, therefore, the foot bath service is the large industry of one in the health preserving.
Present existing health preserving product category is various, but the following shortcoming of tool: (1) effect is single, and most health preserving product just has a certain specially good effect pointedly; (2) orally use, archaism cloud " being three minutes poison of medicine ", oral medication can cause the harmful components in the medicine to be detained, to accumulate, thereby cause the injury to the vitals such as liver, kidney in the human body.
Therefore, invent a kind of many effects and health preserving product that can external and have important practical value.
Summary of the invention
The present invention's the first purpose has provided a kind of medicine, and its main component is as follows: Radix Morindae Officinalis (wine is processed) 1.2～1.5%, Herba Cistanches (wine is processed) 0.5～1.5%, Cornu Cervi Pantotrichum (unhairing) 0.1～0.5%, Fructus Lycii 1.0～1.6%, Flos Albiziae 1.0～3.5%, Lignum Santali Albi 0.1～0.5%, Herba Artemisiae Scopariae 0.1～0.5%, RHIZONA GASTRODIAE 1.2～1.8%, Cortex Eucommiae(processed with salt) 1.0～1.2%, Folium Ginkgo 0.1～0.5%, the Radix Astragali 1.0～1.2%, Lignum Aquilariae Resinatum 0.1～0.5%, Folium Artemisiae Argyi 1.2～4.5%, Pericarpium Citri Reticulatae 0.1～0.2%, Fructus Crataegi 0.1～0.2%, Fructus Schisandrae Chinensis 1.2～3.5% Radix Et Rhizoma Rhei 1.0～2.5%, Radix Paeoniae Rubra 1.2～2.3%, Olibanum (wine is processed) 1.5～2.5%, Myrrha (processed with vinegar) 0.5～2.5%, Radix Angelicae Sinensis 1.0～1.2%, cooked Radix Notoginseng 1.0～1.5%, Stigma Croci 0.1～0.5%, lavandula angustifolia 1.5～2.3%, Semen Persicae 0.1～0.5%, Radix Polygalae 1.2～1.5%, Ganoderma sinense Zhao Xu et Zhang 0.1～0.5%, Radix Rhodiolae 0.1～0.5%, Radix Polygoni Multiflori (wine is processed) 1.0～2.5%, Rhizoma Polygonati (wine is processed) 0.1～0.5%, Radix Sophorae Flavescentis 0.1～0.5%, Fructus Cnidii 0.1～0.5%, Rhizoma Smilacis Glabrae 0.1～0.5%, Radix Aconiti Lateralis Preparata 0.5～1.5%, Borneolum Syntheticum 1.0～1.5%, Rhizoma Polygonati Odorati 0.1～0.5%, Flos Carthami 1.5～2.5%, Ramulus Mori 1.0～1.5%, Sanguis Draxonis 0.1～0.2%, Radix Angelicae Pubescentis 1.0～1.5%, Rhizoma Chuanxiong 1.0～1.5%, Ramulus Cinnamomi 0.1～0.5%, Fructus Gardeniae Preparatus 1.0～3.5%, Radix Scutellariae 1.5～2.5%, Cortex Phellodendri 1.5～3.5%, Herba Lycopodii 1.6～2.5%, the Radix Angelicae Dahuricae 1.8～2.5%, Poria 1.0～1.5%, Margarita 1.5～2.5%, Herba speranskiae tuberculatae 1.5～2.5%, Rhizoma Zingiberis 1.5～3.5%, Bulbus Lilii 0.1～0.5%, Semen Ziziphi Spinosae 1.2～2.5%, Radix Salviae Miltiorrhizae 1.2～2.5%, Radix Ginseng 0.1～0.2% and Magnetitum 0.5～1.5%.
After stirring with wine respectively, Radix Morindae Officinalis, Herba Cistanches, Olibanum, Radix Polygoni Multiflori and Rhizoma Polygonati after Radix Morindae Officinalis in this medicine (wine is processed), Herba Cistanches (wine is processed), Olibanum (wine is processed), Radix Polygoni Multiflori (wine is processed), Rhizoma Polygonati (wine is processed) refer to clean selecting materials dry gained Radix Morindae Officinalis, Herba Cistanches, Olibanum, Radix Polygoni Multiflori and Rhizoma Polygonati spice; Myrrha (processed with vinegar) dries the gained Myrrha after referring to stir with vinegar; Cornu Cervi Pantotrichum (unhairing) refers to remove the Cornu Cervi Pantotrichum of hair.
Contain ginsenoside, ginseng diol saponin, Effects of Ginseng Root Saponins, ginsenoside Rb1, baicalin, matrine, globulariacitrin, chlorogenic acid, Radix Notoginseng total arasaponins, total flavones, ligustrazine, Inokopolyose, Dihuang polysaccharide, pachyman in the composition of this medicine, the multiple beneficial materials such as gutta-percha, its effect is as follows: the ginsenoside has protective action to radiation-induced cell membrane damage; Ginseng diol saponin has protective effect to myocardial ischemia-reperfusion dog cardiac function; Effects of Ginseng Root Saponins has obvious anti-DNA damnification and antimutagenic effect; The ginsenoside Rb1 lowly has protective effect to the irritability sexual behaviour; Radix Notoginseng total arasaponins significantly improves sarcoplasm nethike embrane calcium pump activity in the myocardial cell, reduces myocardial cell Ca
2+, the dog myocardial ischemia reperfusion injury is had protective effect.Contain in addition starch, protein, fat, tannin, flavone compound, phenolic compound and trace volatile oil, also contain and have bioactive trace elements iron, aluminum, zinc, silver, cobalt, cadmium, titanium, molybdenum, manganese etc., contain a small amount of alkaloid in leaf and the stem.Skin whitening is arranged, the functions such as the mental sleep of resisting fatigue, defying age and raising and physical function.
The interaction of the corresponding gene of the different effective ingredient in this medicine and protein expression target spot, the content of raising catalase, superoxide dismutase activity and reduced glutathion, adenosine triphosphate.The 10 strain virus cytopathogenic effects relevant with respiratory tract infection all there is in various degree inhibitory action, comes Gastrointestinal motility adjustment by content in hypothalamus and gastrointestinal tract such as gastrin, motilin, the Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 that affects excited gastrointestinal motility and the somatostatin that suppresses gastrointestinal motility, vasoactive intestinal peptide; Have good biologic activity, according to what of expression with monarch, the minister of compound recipe, help, make theory and using dosage to be associated, totally improve curative effect.
This medicine has more unique hydrophilic infiltration composition, the Chinese medicine bioactive ingredients that gets rid of illness is transformed into micromolecule from macromole, effective ingredient is the through teleneuron of distributed by capillarity wall rapidly, activate the meridians microcirculation by epidermal tissue's osmosis, can powerful metabolism discharge the endotoxin that the stasis of blood stagnates in the body, realize the identification of many target spots of Chinese medicine targeting, the original disease of health has corresponding sensation, everyone organismic internal environment is obstructed, body constitution is different, the toxin color of discharging is also different, and the color of water all can change after the foot bath, opens the toxin expelling of real meaning.
Generally speaking, this medicine has the blood microcirculation of improvement, and unobstructed lympha toxin expelling enhances metabolism, the balance cranial nerve improves sleep, regulate the circulation of foot and systemic blood, activate trophocyte from top to bottom, the intestine moistening toxin expelling relieves inflammation or internal heat, desalinate rapidly face's mottle, the refinement wrinkle, expansible foot blood vessel microcirculation is used for the aspect effects such as the mental sleep of resisting fatigue, defying age and raising and physical function.
Preferably, the main component of this medicine is as follows: Radix Morindae Officinalis (wine is processed) 1.5%, Herba Cistanches (wine is processed) 1.5%, Cornu Cervi Pantotrichum (unhairing) 0.5%, Fructus Lycii 1.6%, Flos Albiziae 3.5%, Lignum Santali Albi 0.5%, Herba Artemisiae Scopariae 0.5%, RHIZONA GASTRODIAE 1.8%, Cortex Eucommiae(processed with salt) 1.2%, Folium Ginkgo 0.5%, the Radix Astragali 1.2%, Lignum Aquilariae Resinatum 0.5%, Folium Artemisiae Argyi 4.5%, Pericarpium Citri Reticulatae 0.2%, Fructus Crataegi 0.2%, Fructus Schisandrae Chinensis 3.5%, Radix Et Rhizoma Rhei 2.5%, Radix Paeoniae Rubra 2.3%, Olibanum (wine is processed) 2.5%, Myrrha (processed with vinegar) 2.5%, Radix Angelicae Sinensis 1.2%, cooked Radix Notoginseng 1.5%, Stigma Croci 0.5%, lavandula angustifolia 2.3% Semen Persicae 0.5%, Radix Polygalae 1.5%, Ganoderma sinense Zhao Xu et Zhang 0.5%, Radix Rhodiolae 0.5%, Radix Polygoni Multiflori (wine is processed) 2.5%, Rhizoma Polygonati (wine is processed) 0.5%, Radix Sophorae Flavescentis 0.5%, Fructus Cnidii 0.5%, Rhizoma Smilacis Glabrae 0.5%, Radix Aconiti Lateralis Preparata 1.5%, Borneolum Syntheticum 1.5%, Rhizoma Polygonati Odorati 0.5%, Flos Carthami 2.5%, Ramulus Mori 1.5%, Sanguis Draxonis 0.2%, Radix Angelicae Pubescentis 1.5%, Rhizoma Chuanxiong 1.5%, Ramulus Cinnamomi 0.5%, Fructus Gardeniae Preparatus 3.5%, Radix Scutellariae 2.5%, Cortex Phellodendri 3.5%, Herba Lycopodii 2.5%, the Radix Angelicae Dahuricae 2.5%, Poria 1.5%, Margarita 2.5%, Herba speranskiae tuberculatae 2.5%, Rhizoma Zingiberis 3.5%, Bulbus Lilii 0.5%, Semen Ziziphi Spinosae 2.5%, Radix Salviae Miltiorrhizae 2.5%, Radix Ginseng 0.2% and Magnetitum 1.5%.
After stirring with wine respectively, Radix Morindae Officinalis, Herba Cistanches, Olibanum, Radix Polygoni Multiflori and Rhizoma Polygonati after Radix Morindae Officinalis in this medicine (wine is processed), Herba Cistanches (wine is processed), Olibanum (wine is processed), Radix Polygoni Multiflori (wine is processed), Rhizoma Polygonati (wine is processed) refer to clean selecting materials dry gained Radix Morindae Officinalis, Herba Cistanches, Olibanum, Radix Polygoni Multiflori and Rhizoma Polygonati spice; Myrrha (processed with vinegar) dries the gained Myrrha after referring to stir with vinegar; Cornu Cervi Pantotrichum (unhairing) refers to remove the Cornu Cervi Pantotrichum of hair.
The second purpose of the present invention is the preparation method that discloses the above medicine, may further comprise the steps:
(1) selects raw material: choose the plant of high-quality as raw material, select various medicinal plants when active constituent content is the highest, to gather;
(2) clean: will clean as the plant of raw material, and remove dirt, slag, it is thoroughly cleaned up;
(3) the preliminary pulverizing: each kind of plant after cleaning is mixed, tentatively pulverize through grinder, preferred, the preliminary pulverizing is the granule of 80～120 order sizes;
(4) fermentation: will evenly pave through the plant granule of preliminary pulverizing, and spray to infiltrate with wine and ferment, and obtain fermented product, and preferably spray infiltration with 50～60 degree grain wine, and stir fermentation enzyme zymolysis in 7～15 days;
(5) cold drying: fermented product is carried out oven drying at low temperature, obtain drying composite, preferred daylight dry in the sun 2～3 days makes its bone dry;
(6) fine gtinding: drying composite is ground to is equal to or greater than 200 purpose fine powders, namely get drug products.
The preparation method of medicine of the present invention is through selecting raw material, cleaning, fermentation, sun dehydration and mechanical activation comminution, and technique is advanced unique, and dosage form can change, and does not add any other chemical reagent, environmental protection.
Description of drawings
Fig. 1 is the process flow diagram of preparation medicine of the present invention.
The specific embodiment
Describe the present invention in detail below in conjunction with accompanying drawing and specific embodiment, be used for explaining the present invention in this illustrative examples of the present invention and explanation, but not as a limitation of the invention.
Embodiment 1:
A kind of medicine, its main component is as follows: Radix Morindae Officinalis (wine is processed) 1.2～1.5%, Herba Cistanches (wine is processed) 0.5～1.5%, Cornu Cervi Pantotrichum (unhairing) 0.1～0.5%, Fructus Lycii 1.0～1.6%, Flos Albiziae 1.0～3.5%, Lignum Santali Albi 0.1～0.5%, Herba Artemisiae Scopariae 0.1～0.5%, RHIZONA GASTRODIAE 1.2～1.8%, Cortex Eucommiae(processed with salt) 1.0～1.2%, Folium Ginkgo 0.1～0.5%, the Radix Astragali 1.0～1.2%, Lignum Aquilariae Resinatum 0.1～0.5%, Folium Artemisiae Argyi 1.2～4.5%, Pericarpium Citri Reticulatae 0.1～0.2%, Fructus Crataegi 0.1～0.2%, Fructus Schisandrae Chinensis 1.2～3.5% Radix Et Rhizoma Rhei 1.0～2.5%, Radix Paeoniae Rubra 1.2～2.3%, Olibanum (wine is processed) 1.5～2.5%, Myrrha (processed with vinegar) 0.5～2.5%, Radix Angelicae Sinensis 1.0～1.2%, cooked Radix Notoginseng 1.0～1.5%, Stigma Croci 0.1～0.5%, lavandula angustifolia 1.5～2.3%, Semen Persicae 0.1～0.5%, Radix Polygalae 1.2～1.5%, Ganoderma sinense Zhao Xu et Zhang 0.1～0.5%, Radix Rhodiolae 0.1～0.5%, Radix Polygoni Multiflori (wine is processed) 1.0～2.5%, Rhizoma Polygonati (wine is processed) 0.1～0.5%, Radix Sophorae Flavescentis 0.1～0.5%, Fructus Cnidii 0.1～0.5%, Rhizoma Smilacis Glabrae 0.1～0.5%, Radix Aconiti Lateralis Preparata 0.5～1.5%, Borneolum Syntheticum 1.0～1.5%, Rhizoma Polygonati Odorati 0.1～0.5%, Flos Carthami 1.5～2.5%, Ramulus Mori 1.0～1.5%, Sanguis Draxonis 0.1～0.2%, Radix Angelicae Pubescentis 1.0～1.5%, Rhizoma Chuanxiong 1.0～1.5%, Ramulus Cinnamomi 0.1～0.5%, Fructus Gardeniae Preparatus 1.0～3.5%, Radix Scutellariae 1.5～2.5%, Cortex Phellodendri 1.5～3.5%, Herba Lycopodii 1.6～2.5%, the Radix Angelicae Dahuricae 1.8～2.5%, Poria 1.0～1.5%, Margarita 1.5～2.5%, Herba speranskiae tuberculatae 1.5～2.5%, Rhizoma Zingiberis 1.5～3.5%, Bulbus Lilii 0.1～0.5%, Semen Ziziphi Spinosae 1.2～2.5%, Radix Salviae Miltiorrhizae 1.2～2.5%, Radix Ginseng 0.1～0.2% and Magnetitum 0.5～1.5%.
After stirring with wine respectively, Radix Morindae Officinalis, Herba Cistanches, Olibanum, Radix Polygoni Multiflori and Rhizoma Polygonati after Radix Morindae Officinalis in this medicine (wine is processed), Herba Cistanches (wine is processed), Olibanum (wine is processed), Radix Polygoni Multiflori (wine is processed), Rhizoma Polygonati (wine is processed) refer to clean selecting materials dry gained Radix Morindae Officinalis, Herba Cistanches, Olibanum, Radix Polygoni Multiflori and Rhizoma Polygonati spice; Myrrha (processed with vinegar) dries the gained Myrrha after referring to stir with vinegar; Cornu Cervi Pantotrichum (unhairing) refers to remove the Cornu Cervi Pantotrichum of hair.
Embodiment 2:
A kind of medicine, its main component is as follows: Radix Morindae Officinalis (wine is processed) 1.5%, Herba Cistanches (wine is processed) 1.5%, Cornu Cervi Pantotrichum (unhairing) 0.5%, Fructus Lycii 1.6%, Flos Albiziae 3.5%, Lignum Santali Albi 0.5%, Herba Artemisiae Scopariae 0.5%, RHIZONA GASTRODIAE 1.8%, Cortex Eucommiae(processed with salt) 1.2%, Folium Ginkgo 0.5%, the Radix Astragali 1.2%, Lignum Aquilariae Resinatum 0.5%, Folium Artemisiae Argyi 4.5%, Pericarpium Citri Reticulatae 0.2%, Fructus Crataegi 0.2%, Fructus Schisandrae Chinensis 3.5%, Radix Et Rhizoma Rhei 2.5%, Radix Paeoniae Rubra 2.3%, Olibanum (wine is processed) 2.5%, Myrrha (processed with vinegar) 2.5%, Radix Angelicae Sinensis 1.2%, cooked Radix Notoginseng 1.5%, Stigma Croci 0.5%, lavandula angustifolia 2.3% Semen Persicae 0.5%, Radix Polygalae 1.5%, Ganoderma sinense Zhao Xu et Zhang 0.5%, Radix Rhodiolae 0.5%, Radix Polygoni Multiflori (wine is processed) 2.5%, Rhizoma Polygonati (wine is processed) 0.5%, Radix Sophorae Flavescentis 0.5%, Fructus Cnidii 0.5%, Rhizoma Smilacis Glabrae 0.5%, Radix Aconiti Lateralis Preparata 1.5%, Borneolum Syntheticum 1.5%, Rhizoma Polygonati Odorati 0.5%, Flos Carthami 2.5%, Ramulus Mori 1.5%, Sanguis Draxonis 0.2%, Radix Angelicae Pubescentis 1.5%, Rhizoma Chuanxiong 1.5%, Ramulus Cinnamomi 0.5%, Fructus Gardeniae Preparatus 3.5%, Radix Scutellariae 2.5%, Cortex Phellodendri 3.5%, Herba Lycopodii 2.5%, the Radix Angelicae Dahuricae 2.5%, Poria 1.5%, Margarita 2.5%, Herba speranskiae tuberculatae 2.5%, Rhizoma Zingiberis 3.5%, Bulbus Lilii 0.5%, Semen Ziziphi Spinosae 2.5%, Radix Salviae Miltiorrhizae 2.5%, Radix Ginseng 0.2% and Magnetitum 1.5%.
After stirring with wine respectively, Radix Morindae Officinalis, Herba Cistanches, Olibanum, Radix Polygoni Multiflori and Rhizoma Polygonati after Radix Morindae Officinalis in this medicine (wine is processed), Herba Cistanches (wine is processed), Olibanum (wine is processed), Radix Polygoni Multiflori (wine is processed), Rhizoma Polygonati (wine is processed) refer to clean selecting materials dry gained Radix Morindae Officinalis, Herba Cistanches, Olibanum, Radix Polygoni Multiflori and Rhizoma Polygonati spice; Myrrha (processed with vinegar) dries the gained Myrrha after referring to stir with vinegar; Cornu Cervi Pantotrichum (unhairing) refers to remove the Cornu Cervi Pantotrichum of hair.
Below for using the case of drug products of the present invention:
Case 1: certain woman, 46 years old, long-term insomnia can only be slept 2～3 hours every night, and daytime, sleepy health was tired, used drug products of the present invention 15 days, and symptom is clearly better and can sleeps peacefully 5～6 hours, and sleep quality is splendid.Concrete using method is for the warm water soaking biped of this drug products and 40 ℃～45 ℃ 30-40 minute.
Case 2: certain woman, 30 years old, face had speckle, and color is gloomy, and skin layer is coarse, and menoxenia uses drug products of the present invention about 28 days, and skin is obviously pale, delicacy.Concrete using method is for the warm water soaking biped of this drug products and 40 ℃～45 ℃ 30-40 minute.
Case 3: certain man, 36 years old, often to drink, the greasy seafood of happiness edible oil suffers from gout, and after using drug products of the present invention, the elimination of swelling and ache is clearly better.Concrete using method is for the warm water soaking biped of this drug products and 40 ℃～45 ℃ 30-40 minute.
Case 4: certain woman, 23 years old, usually weak, often brothers were cold and cool, and abdominal pain in menstruation is had rosy cheeks after using drug products of the present invention, and brothers turn temperature, and dysmenorrhea is eliminated.Concrete using method is for the warm water soaking biped of this drug products and 40 ℃～45 ℃ 30-40 minute.
Embodiment 3:
Fig. 1 is the preparation method of the embodiment of the invention 1 and embodiment 2 described medicines, and as can be seen from Figure 1, process for preparing medicine of the present invention is as follows:
The first step: select raw material, choose the required medicinal plants of high-quality as raw material, select various medicinal plants when active constituent content is the highest, to gather;
Second step: clean, will clean as the plant of raw material, remove dirt, slag, it is thoroughly cleaned up;
The 3rd step: the preliminary pulverizing, each kind of plant after cleaning is mixed, tentatively pulverize through grinder, preferred, the preliminary pulverizing is the granule of 80～120 order sizes;
The 4th step: fermentation, will evenly pave through the plant granule of preliminary pulverizing, spray to infiltrate with wine and ferment, obtain fermented product, preferably spray infiltration with 50～60 degree grain wine, stir fermentation enzyme zymolysis in 7～15 days;
The 5th step: cold drying, fermented product is carried out oven drying at low temperature, obtain drying composite, preferred daylight dry in the sun 2～3 days makes its bone dry;
The 6th step: fine gtinding, drying composite is ground to is greater than or equal to 200 purpose fine powders, namely get drug products of the present invention.
Medicine of the present invention with and preparation method thereof have a following advantage:
1, contains ginsenoside, ginseng diol saponin, Effects of Ginseng Root Saponins, ginsenoside Rb1, baicalin, matrine, globulariacitrin, chlorogenic acid, Radix Notoginseng total arasaponins, total flavones, ligustrazine, Inokopolyose, Dihuang polysaccharide, pachyman in the composition of this medicine, the multiple beneficial materials such as gutta-percha, its effect is as follows: the ginsenoside has protective action to radiation-induced cell membrane damage; Ginseng diol saponin has protective effect to myocardial ischemia-reperfusion dog cardiac function; Effects of Ginseng Root Saponins has obvious anti-DNA damnification and antimutagenic effect; The ginsenoside Rb1 lowly has protective effect to the irritability sexual behaviour; Radix Notoginseng total arasaponins significantly improves sarcoplasm nethike embrane calcium pump activity in the myocardial cell, reduces myocardial cell Ca
2+, the dog myocardial ischemia reperfusion injury is had protective effect.Contain in addition starch, protein, fat, tannin, flavone compound, phenolic compound and trace volatile oil, also contain and have bioactive trace elements iron, aluminum, zinc, silver, cobalt, cadmium, titanium, molybdenum, manganese etc., contain a small amount of alkaloid in leaf and the stem.The aspect effects such as the mental sleep of resisting fatigue, defying age and raising and physical function are arranged.
2, the interaction of the corresponding gene of the different effective ingredient in this medicine and protein expression target spot, the content of raising catalase, superoxide dismutase activity and reduced glutathion, adenosine triphosphate.The 10 strain virus cytopathogenic effects relevant with respiratory tract infection all there is in various degree inhibitory action, comes Gastrointestinal motility adjustment by content in hypothalamus and gastrointestinal tract such as gastrin, motilin, the Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 that affects excited gastrointestinal motility and the somatostatin that suppresses gastrointestinal motility, vasoactive intestinal peptide; Has good biologic activity.According to what of expression with monarch, the minister of compound recipe, help, make theory and using dosage to be associated, totally improve curative effect.
3, this medicine has more unique hydrophilic infiltration composition, the Chinese medicine bioactive ingredients that gets rid of illness is transformed into micromolecule from macromole, effective ingredient is the through teleneuron of distributed by capillarity wall rapidly, activate the meridians microcirculation by epidermal tissue's osmosis, can powerful metabolism discharge the endotoxin that the stasis of blood stagnates in the body, realize the identification of many target spots of Chinese medicine targeting, the original disease of health has corresponding sensation, everyone organismic internal environment is obstructed, body constitution is different, the toxin color of discharging is also different, and the color of water all can change after the foot bath, opens the toxin expelling of real meaning.
But 4, medicine external of the present invention namely is used for foot bath, does not need just can reach certain curative effect by oral.
5, the preparation method of medicine of the present invention is through selecting raw material, cleaning, fermentation, sun dehydration and mechanical activation comminution, and technique is simple, and does not add any other chemical reagent, environmental protection.
In sum, medicine of the present invention is compared with other foot bath product, the hydrophilic infiltration composition of tool uniqueness, the Chinese medicine bioactive ingredients that gets rid of illness is transformed into micromolecule from macromole, effective ingredient is the through teleneuron of distributed by capillarity wall rapidly, activate the meridians microcirculation by epidermal tissue's osmosis, can powerful metabolism discharge the endotoxin that the stasis of blood stagnates in the body, realize the identification of many target spots of Chinese medicine targeting, the original disease of health has corresponding sensation, and everyone organismic internal environment is obstructed, body constitution is different, the toxin color of discharging is also different, and the color of water all can change after the foot bath, is the high-tech molecule foot bath element of a new generation.This medicine can improve blood microcirculation, and unobstructed lympha toxin expelling enhances metabolism, remove free radical, regulate the circulation of foot and systemic blood, activate trophocyte from top to bottom, the intestine moistening toxin expelling that relieves inflammation or internal heat is desalinated rapidly face's mottle, black eye, the refinement wrinkle, pachylosis, the warm-heat effect of water, expansible foot blood vessel microcirculation, increase skin surface temperature, the epiderm skin sweat gland has secretion, absorption and drainage, thermoregulation, breathing, the effects such as thoughts and feelings; Because itself just can absorb the drug, as by hot water, then being more conducive to drug effect plays a role at human body, thereby strengthen the circulation of foot and systemic blood, the warm water soaking biped that healthy human is 40 ℃～45 ℃ 30-40 minute, it is 9～12 times that the flow of its systemic blood increases the women, the male be 12～15 times because the increase of blood circulation amount, thereby regulate each endocrine function, impel each endocrine body of gland to secrete various hormones, such as the thyroxin of thyroid secretion, the epinephrine of acth secretion, these hormones toxin expelling that all can enhance metabolism, make in the water after bathing and to see a large amount of interior metabolism products, such as the lactic acid crystallization, creatinine, uric acid etc. are discharged from, and open the toxin expelling of real meaning, whole body is light after bathing, spiritual happiness.
More than technical scheme that the embodiment of the invention is provided be described in detail, used specific case herein principle and the embodiment of the embodiment of the invention are set forth, the explanation of above embodiment is only applicable to help to understand the principle of the embodiment of the invention; Simultaneously, for one of ordinary skill in the art, according to the embodiment of the invention, all will change on the specific embodiment and range of application, in sum, this description should not be construed as limitation of the present invention.
Claims (6)
1. a medicine is characterized in that its main component is as follows: Radix Morindae Officinalis (wine is processed) 1.2～1.5%, Herba Cistanches (wine is processed) 0.5～1.5%, Cornu Cervi Pantotrichum (unhairing) 0.1～0.5%, Fructus Lycii 1.0～1.6%, Flos Albiziae 1.0～3.5%, Lignum Santali Albi 0.1～0.5%, Herba Artemisiae Scopariae 0.1～0.5%, RHIZONA GASTRODIAE 1.2～1.8%, Cortex Eucommiae(processed with salt) 1.0～1.2%, Folium Ginkgo 0.1～0.5%, the Radix Astragali 1.0～1.2%, Lignum Aquilariae Resinatum 0.1～0.5%, Folium Artemisiae Argyi 1.2～4.5%, Pericarpium Citri Reticulatae 0.1～0.2%, Fructus Crataegi 0.1～0.2%, Fructus Schisandrae Chinensis 1.2～3.5% Radix Et Rhizoma Rhei 1.0～2.5%, Radix Paeoniae Rubra 1.2～2.3%, Olibanum (wine is processed) 1.5～2.5%, Myrrha (processed with vinegar) 0.5～2.5%, Radix Angelicae Sinensis 1.0～1.2%, cooked Radix Notoginseng 1.0～1.5%, Stigma Croci 0.1～0.5%, lavandula angustifolia 1.5～2.3%, Semen Persicae 0.1～0.5%, Radix Polygalae 1.2～1.5%, Ganoderma sinense Zhao Xu et Zhang 0.1～0.5%, Radix Rhodiolae 0.1～0.5%, Radix Polygoni Multiflori (wine is processed) 1.0～2.5%, Rhizoma Polygonati (wine is processed) 0.1～0.5%, Radix Sophorae Flavescentis 0.1～0.5%, Fructus Cnidii 0.1～0.5%, Rhizoma Smilacis Glabrae 0.1～0.5%, Radix Aconiti Lateralis Preparata 0.5～1.5%, Borneolum Syntheticum 1.0～1.5%, Rhizoma Polygonati Odorati 0.1～0.5%, Flos Carthami 1.5～2.5%, Ramulus Mori 1.0～1.5%, Sanguis Draxonis 0.1～0.2%, Radix Angelicae Pubescentis 1.0～1.5%, Rhizoma Chuanxiong 1.0～1.5%, Ramulus Cinnamomi 0.1～0.5%, Fructus Gardeniae Preparatus 1.0～3.5%, Radix Scutellariae 1.5～2.5%, Cortex Phellodendri 1.5～3.5%, Herba Lycopodii 1.6～2.5%, the Radix Angelicae Dahuricae 1.8～2.5%, Poria 1.0～1.5%, Margarita 1.5～2.5%, Herba speranskiae tuberculatae 1.5～2.5%, Rhizoma Zingiberis 1.5～3.5%, Bulbus Lilii 0.1～0.5%, Semen Ziziphi Spinosae 1.2～2.5%, Radix Salviae Miltiorrhizae 1.2～2.5%, Radix Ginseng 0.1～0.2% and Magnetitum 0.5～1.5%.
2. medicine according to claim 1 is characterized in that its main component is as follows: Radix Morindae Officinalis (wine is processed) 1.5%, Herba Cistanches (wine is processed) 1.5%, Cornu Cervi Pantotrichum (unhairing) 0.5%, Fructus Lycii 1.6%, Flos Albiziae 3.5%, Lignum Santali Albi 0.5%, Herba Artemisiae Scopariae 0.5%, RHIZONA GASTRODIAE 1.8%, Cortex Eucommiae(processed with salt) 1.2%, Folium Ginkgo 0.5%, the Radix Astragali 1.2%, Lignum Aquilariae Resinatum 0.5%, Folium Artemisiae Argyi 4.5%, Pericarpium Citri Reticulatae 0.2%, Fructus Crataegi 0.2%, Fructus Schisandrae Chinensis 3.5%, Radix Et Rhizoma Rhei 2.5%, Radix Paeoniae Rubra 2.3%, Olibanum (wine is processed) 2.5%, Myrrha (processed with vinegar) 2.5%, Radix Angelicae Sinensis 1.2%, cooked Radix Notoginseng 1.5%, Stigma Croci 0.5%, lavandula angustifolia 2.3% Semen Persicae 0.5%, Radix Polygalae 1.5%, Ganoderma sinense Zhao Xu et Zhang 0.5%, Radix Rhodiolae 0.5%, Radix Polygoni Multiflori (wine is processed) 2.5%, Rhizoma Polygonati (wine is processed) 0.5%, Radix Sophorae Flavescentis 0.5%, Fructus Cnidii 0.5%, Rhizoma Smilacis Glabrae 0.5%, Radix Aconiti Lateralis Preparata 1.5%, Borneolum Syntheticum 1.5%, Rhizoma Polygonati Odorati 0.5%, Flos Carthami 2.5%, Ramulus Mori 1.5%, Sanguis Draxonis 0.2%, Radix Angelicae Pubescentis 1.5%, Rhizoma Chuanxiong 1.5%, Ramulus Cinnamomi 0.5%, Fructus Gardeniae Preparatus 3.5%, Radix Scutellariae 2.5%, Cortex Phellodendri 3.5%, Herba Lycopodii 2.5%, the Radix Angelicae Dahuricae 2.5%, Poria 1.5%, Margarita 2.5%, Herba speranskiae tuberculatae 2.5%, Rhizoma Zingiberis 3.5%, Bulbus Lilii 0.5%, Semen Ziziphi Spinosae 2.5%, Radix Salviae Miltiorrhizae 2.5%, Radix Ginseng 0.2% and Magnetitum 1.5%.
3. such as the preparation method of medicine as described in claim 1 or 2, it is characterized in that may further comprise the steps:
(1) selects raw material: choose the plant of high-quality as raw material;
(2) clean: will clean as the plant of raw material;
(3) the preliminary pulverizing: the plant after cleaning is tentatively pulverized through grinder;
(4) fermentation: will evenly pave through the preliminary plant granule of pulverizing, and spray to infiltrate with wine and ferment, and obtain fermented product;
(5) cold drying: fermented product is carried out oven drying at low temperature, obtain drying composite;
(6) fine gtinding: drying composite is ground to is greater than or equal to 200 purpose fine powders, namely get drug products.
4. the preparation method of described medicine according to claim 3 is characterized in that described 80～120 purpose granules that tentatively are crushed to.
5. the preparation method of described medicine according to claim 3 is characterized in that described cold drying is daylight dry in the sun 2～3 days.
6. the preparation method of described medicine according to claim 3 is characterized in that described fermentation infiltrates for spraying with 50～60 degree grain wine, stirs fermentation enzyme zymolysis in 7～15 days.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2307591Y (en) * | 1997-02-05 | 1999-02-17 | 陈财先 | Multi-effect health-care pillow with Chinese traditional herb, western medicine flower-and-plant and mineral substance |
| CN102014940A (en) * | 2008-05-02 | 2011-04-13 | 株式会社太平洋 | Medicinal plants extract using processing of herbal medicine and composition of skin external application comprising the same |
-
2012
- 2012-04-12 CN CN201210106927.4A patent/CN103372178B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2307591Y (en) * | 1997-02-05 | 1999-02-17 | 陈财先 | Multi-effect health-care pillow with Chinese traditional herb, western medicine flower-and-plant and mineral substance |
| CN102014940A (en) * | 2008-05-02 | 2011-04-13 | 株式会社太平洋 | Medicinal plants extract using processing of herbal medicine and composition of skin external application comprising the same |
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