CN108837145A - A kind of compound metallothionein pill of lead discharging mercury and preparation method thereof - Google Patents

A kind of compound metallothionein pill of lead discharging mercury and preparation method thereof Download PDF

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CN108837145A
CN108837145A CN201810953675.6A CN201810953675A CN108837145A CN 108837145 A CN108837145 A CN 108837145A CN 201810953675 A CN201810953675 A CN 201810953675A CN 108837145 A CN108837145 A CN 108837145A
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metallothionein
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潘飞
寿韬
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Wuhan Ma Ke Le Fei Lin Biotechnology Co Ltd
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Wuhan Ma Ke Le Fei Lin Biotechnology Co Ltd
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Abstract

The invention discloses the compound metallothionein pills of a lead discharging mercury.It is made of metallothionein, active collagen, calcium carbonate, vitamin B1, vitamin C, microcrystalline cellulose, magnesium stearate, fructus lycii, ginkgo leaf, Schisandra chinensis, semen sojae atricolor, Radix Astragali, Radix Angelicae Sinensis, physiological saline, dried lily bulb, Radix Glycyrrhizae, eucalyptus honey;The dosage of metallothionein is 0.5~2 parts by weight, the dosage of active collagen is 1~3 parts by weight, the dosage of calcium carbonate is 1~10 parts by weight, the dosage of vitamin B1 is 1~4 parts by weight, ascorbic dosage is 1~5 parts by weight, and the dosage of microcrystalline cellulose is 1~10 parts by weight, and the dosage of magnesium stearate is 1~10 parts by weight, the dosage of fructus lycii is 3~15 parts by weight, and the dosage of ginkgo leaf is 1~10 parts by weight.The present invention has the advantages that exclude the heavy metals toxin, whitening and anti-aging such as internal lead, mercury, arsenic.The invention also discloses a kind of methods for the compound metallothionein pill for preparing lead discharging mercury.

Description

A kind of compound metallothionein pill of lead discharging mercury and preparation method thereof
Technical field
The present invention relates to edible health care products, more specifically say it is a kind of compound metallothionein pill of lead discharging mercury.This The method that invention further relates to prepare a kind of compound metallothionein pill of lead discharging mercury.
Background technique
Metallothionein (metallothionein) is with the low molecular weight egg in conjunction with metal ability and high inducing properties White matter;Metallothionein is rich in the small peptide of cysteine, has high affinity to various heavy;It is that molecular mass is lower, Cysteine residues and the high protein of tenor;Metal in conjunction with metallothionein is mainly cadmium, copper and zinc, extensively Ground is present in from microorganism to the mankind in various biologies, and structure height is conservative;Metallothionein is referred to as MT, the important life of MT Reason function shows that it is a kind of most effective free radical scavenger known today, removes the ability of free radical (OH) about It is thousands of times of SOD, and the ability of scavenging activated oxygen (O) is approximately 25 times of glutathione (GSH), and is had very strong Anti-oxidant activity;The function that MT removes free radical plays it during anti-aging, anti-oxidant pressure and Apoptosis etc. Important function;MT is a kind of potential Apoptosis negative regulatory factor, and is had to normal body cell in chemotherapy certain Protective effect;Since MT has special chemical structure, metal therein has kinetic instability, and sulfydryl has nucleophilicity Tendency, so that MT especially interacts with certain free radicals easily with certain electrophilic agents.
Active collagen is to orient shearing technique using biological enzyme, has abandoned the strong acid generallyd use both at home and abroad, highly basic With the method for single enzymatic treatment (target product not easy to control), according to the requirement of different target product, from fresh animal micromicro control It produces active collagen (polypeptide), ensure that:Collagen (polypeptide) Spatial infrastructure does not make a variation;Amino acid is not destroyed;Ammonia Base acid does not generate racemization;Skin depths can be infiltrated into rapidly, activated fiber sprout cell, generated new collagen;Activation is fine Tieing up sprout cell can:Generate new collagen;The original collagenous fibres at random of tightening, keep collagen more tough, even if generating new Collagen, if cannot make collagenous fibres it is tough, it is sturdy if, cannot equally make skin restore elasticity, skin can not be improved Wrinkle it is worried;Fiber sprout cell has an ability for tightly tightening collagenous fibres at random, but with the increase at age and The influence of ultraviolet light, this ability are constantly weakened, and skin just follows the string;But having active collagen, this ability will It greatly promotes;Under the support of both effects, skin can keep original elasticity well.
Vitamin B1 is also known as thiamine or antineuritic vitamin or anti beriberi vitamin, is white crystal, aerobic Generation dehydrothiamine is oxidized easily in the presence of agent, blue-fluorescence is presented when there is ultraviolet light by the latter.By pyrimidine ring A kind of B family vitamin being combined into thiazole ring by methylene.
Ascorbic structure is a kind of polyol, the 2nd and the 3rd upper two phase in molecule similar to glucose Adjacent enolic hydroxyl easily dissociates and releases H+, therefore has the property of acid, also known as ascorbic acid.Vitamin C has very strong Reproducibility, it is easy to be oxidized to dehydrogenation vitamin C, but its reaction is reversible, and ascorbic acid and hydroascorbic acid With same physiological function, if but hydroascorbic acid continue to aoxidize, generate the ancient happy saccharic acid of diketone, then react irreversible and complete Physiological potency is lost entirely;Vitamin C is also known as ascorbic acid, is a kind of acid polyol containing 6 carbon atoms, molecule Formula is C6H8O6, molecular weight 176.1;Naturally occurring ascorbic acid has L-type and 2 kinds of D type, the latter's inactive;Dimension life Plain C is the flat crystal in no color or smell, soluble easily in water, does not dissolve in organic solvent.
Fructus lycii, also known as fructus lycii, red ear pendant are that maturation of Solanaceae undershrub fructus lycii is real;Fructus lycii integration of drinking and medicinal herbs is gone through History is long, is the rare traditional Chinese medicine having won fame both at home and abroad, early in《Sheng Nong's herbal classic》In be just listed in top grade, be called that " long term usage is made light of one's life by commiting suicide Not old, resistance to cold and heat ";Have and prolong the anti-ageing effect that declines, also known as " but I ";Amino acid there are many containing in fructus lycii, and contain beet The special nutrient compositions such as alkali, zeaxanthine, physalin make it have extraordinary health-care efficacy;Immunosenescence and thin Born of the same parents' apoptosis is closely related, and polysaccharides (LBP) can significantly improve the phagocytic function of phagocyte, improve the proliferation of lymphocyte Ability;Skin aging is mainly due to caused by free-radical oxidation, and polysaccharides, beta carotene contained in fructus lycii are all The antioxidant of strength constitutes powerful antioxygen along with the synergistic effect of trace elements of selenium contained by fructus lycii and vitamin E Change army;In addition, vitamin A can maintain the growth and differentiation of epithelial tissue, dry skin and follicular keratosis are prevented, to play The effect of beautifying face and moistering lotion, moisturizing;Polysaccharides contained by fructus lycii can protect leucocyte, promote body hematopoietic function recovery;This Outside, lycium barbarum also has adjust neuroendocrine, repair ischemic brain damage, mitigate brain edema, improve cerebral function etc. and make With.
Ginkgo leaf is the leaf of Ginkgoaceae plant Ginkgo biloba Ginkgo bilobaL., mild-natured, sweet in flavor, bitter, puckery;Thoughts of returning home warp, lung Through;Brain circlulation can be improved, have the function of protection to brain cell and blood-brain barrier;Learning and memory can be improved, nerve can be protected, subtracted Light auditory nerve damage, to the effect of being significantly improved of aging, dementia, brain disorder;To cardiovascular system, myocardium consumption can be reduced Oxygen amount can protect ischemic myocardium, reduce the generation of arrhythmia cordis, expand blood vessel, inhibit Angiotensin-Converting (ACE);Clearly Except free radical, anti peroxidation of lipid;Anti-platelet activating factor inhibits blood platelet;Have the function of that enhancing biomembrane is stable;It is right Tracheal smooth muscle has direct relexation, plays the role of spasmolysis to gastrointestinal smooth muscle;There is reducing blood lipid;It is micro- with resisting Biological effect;The secretion that can increase sebaceous glands increases dry or aging skin by ruddy color;Have through testing to arteries Dilating effect, and can in addition have hypercholesterolemia effect to the vasoconstrictor effects caused by antiadrenergic drug.
Schisandra chinensis is magnoliaceae schisandra Schisandra chinensis (Turcz.) Baill. or Central China five tastes The dry mature fruit of sub- Schisandra sphenanthera Rehd.et Wils.;Promote body's immunity;It is anti-oxidant And anti-aging;Protect liver, induced liver drug metabolic enzyme;Kobadrin, it is antitumor;It is hypoglycemic;Heart tonifying;Enhance organism adaptation energy Power;Antiulcer;Anti- nephropathy;The effects of antibacterial;Schisandra chinensis organic acid rich in, vitamin, flavonoids, phytosterol and Lignan is that minority has both one of essence, gas, medicinal material of refreshing three big helps;Schisandra chinensis adaptive significances are similar to ginseng;The five tastes Son can enhance body to the defence capability of nonspecific stimulation;Schisandra chinensis can increase cellular immune function, make brain, liver, spleen SOD Activity is remarkably reinforced, thus have improve it is immune, the effect of anti-oxidant, anti-aging.
Semen sojae atricolor (Garlic) semen sojae atricolor is legume soybean (scientific name:Glycinemax (L.) merr) black seeds;It is black The substances such as beans vitamin rich in, lecithin, melanin and lecithin, wherein B family vitamin and content of vitamin E be very Height, has nutrition health-care functions, and microelement also rich in semen sojae atricolor delays body to decline to keeping body function complete Always, reducing blood viscosity, meeting brain is all essential to micro substance demand;Semen sojae atricolor have norcholesterol, kidney tonifying (in Doctor thinks the skin of people, its moist gloss is the nourishing for leaning on our kidney qis, and filling for kidney qi is warm, by moistening for kidney channel;I Often eat semen sojae atricolor and can both supplement kidney qi, kidney yin can also be supplemented.It is so just our skin aging to be made to be delayed, Wrinkle appearance can be reduced;With semen sojae atricolor is eaten often, we can reduce the chloasma due to caused by pigmentation and senile plaque, so Say that semen sojae atricolor is the product of good skin beauty), beneficial spleen, eliminating the phlegm Zhichuan can control cough, and beauty functions, (semen sojae atricolor contains rich anti-aging Rich antioxidant --- vitamin E can remove intracorporal free radical, reduce wrinkle of skin, reach skin maintenance and cosmetic benefits, retain youth Purpose), toxin expelling, weight-reducing improve the health-care effect of anaemia.
Root of the Radix Astragali for leguminous mongolian scutellaria, invigorating qi for strengthening superficies, diuresis myogenic, antitoxin apocenosis are built up health;Radix Astragali has Enhance body's immunity, liver protection, diuresis, anti-aging, resisting stress, decompression and wide antibacterial action;It can eliminate experimental Nephritic proteinuria enhances myocardial contractive power, adjusts blood-sugar content;Radix Astragali can not only coronary artery dilator, improve myocardial blood supply, mention High immune function, and it is capable of the process of delaying cell aging;Radix Astragali containing saponin, sucrose, polysaccharide, a variety of amino acid, folic acid and The various trace elements such as selenium, zinc, copper.
When the dry root for being classified as umbelliferae angelica Angelica sinensis (Oliv.) Diels;With blood-nourishing and The effect of blood, tonifying blood and regulating menstruation, promoting blood circulation and stopping pain, relax bowel and defecation;Have the function of to metabolism, anti-oxidant and removing certainly when giving back By base effect (Radix Angelicae Sinensis to cerebral anoxia, postischemic reperfusion cerebrum lipid peroxide increases apparent inhibiting effect;Institute The ferulic acid contained, which has, directly reduces H2O2 content, and in conjunction with membrane phospholipid acyl ethanol amine, by directly eliminating free radical, inhibits oxygen Change reaction and the damage of the antagonisms free radical to tissue such as radical reaction), anti-inflammatory effect etc.;Main component is rhizoma ligustici in volatile oil Lactone, n-butene base Moo lactone and angelicone etc., the still various trace elements containing vitamin B12 and iron, zinc etc.;Separately containing ferulic acid, Acetophenone, acoradiene, carvacrol, guaiacol, anisic acid, angelica lactone, Diligustilide etc.;There is reduction blood small Plate aggregation and antithrombotic;Promote hemopoietic system function;Reducing blood lipid and anti arteriosclerosis;Anti-oxidant and removing free radical;Enhancing is exempted from Epidemic disease system function;Inhibit I, II, III, type Ⅳ allergy;There is amphicheirality's effect that is excited and inhibiting to uterus;Inhibit forefront Gland hyperplasia;Antigonadotropic hormone;Antiradiation injury;It is antitumor;Anti-inflammatory and antalgic, antibody Monoclonal;Liver protection, cholagogue promote digestion, inhibit The promotion campaign of stomach and intestine;Has the effects that inhibit nervous system, relaxation tracheal smooth muscle, diuresis, antibacterial;It can inhibit in vitro animal Uterus and excited whole animal uterus;Ligustilide has antiasthmatic effect to experimental animal, has suppression to its central nervous system Production is used;Anti-anemia action effect may be related with the microelements such as contained vitamin B12 and iron, zinc.
Lily has very high medical value;Removing toxic substances, reason spleen stomach invigorating, dampness removing disperse accumulation, antitoxic heart-soothing and sedative, the function such as promote blood circulation Effect;The diseases such as overstrain cough, hemoptysis, dysphoria palpitates with fear are cured mainly, have special effect to lung network disease and health-care antisenile is cured;Dried lily bulb contains egg In addition white matter, fat, starch, reduced sugar, sucrose, pectin also contain colchicin, vitamin B;And calcium, phosphorus, iron etc. are a variety of Ingredient;Dried lily bulb has the effects that moistening lung to arrest cough, antitoxic heart-soothing and sedative, beautifying face and moistering lotion, cancer-resisting;Lily is pure white delicate and charming, and fresh goods is rich It is beneficial to skin cell metabolism containing lymphatic temperament and vitamin.
Radix Glycyrrhizae is glycyrrhizic legume Glycyrrhiza uralensis Fisch., swollen fruit Radix Glycyrrhiza The dry root and rhizome of inflata Bat. or glycyrrhiza glabra Glycyrrhiza glabra L.;(heart to be used for invigorating the spleen and benefiting qi The deficiency of vital energy, palpitation and severe palpitation, knotted pulse and deficiency of spleen-QI and stomach-QI, fatigue and weakness etc.), clearing heat and detoxicating (ulcer sores, abscess of throat are used for, Wet poison has antibacterial and anti-inflammation functions.Can also be used for reducing the detoxication of other Chinese medicines), (Radix Glycyrrhizae has relieving cough and reducing sputum work to expelling phlegm and arresting coughing With being used for tracheitis, coughing with a lot of sputum caused by the disease of pulmonary emphysema, asthma, glutinous phlegm the diseases such as is not easy to be discharged), relieving spasm to stop pain (is used for stomach Bitterly, abdominal pain and gastrocnemius contraction urgency pain etc., often with Chinese herbaceous peony with use, the curative effect for controlling contraction urgency pain can be significantly increased), coordinating the drug actions of a prescription it Effect.It is usually used in weakness of the spleen and the stomach, fatigue and weakness, shortness of breath and palpitation, coughing with a lot of sputum, stomach duct and abdomen, four limbs contraction, carbuncle sore tumefacting virus delays Solve drug toxicity, strong.
The effect of eucalyptus honey color is sparkling and crystal-clear, and color is empty shallow amber, heat-clearing bowl spares, detoxify and moisturize;It is used as medicine with eucalyptus honey, there is benefit The functions such as middle QI invigorating, cough-relieving, ease constipation, removing toxic substances, aid digestion;In addition, colour purity taste is fragrant, and it is full of nutrition, contain glucose and tartaric acid 70% More than, there are also multivitamin and inorganic salts, organic acid enzyme, there is the biotin for promoting growth in humans and vigor, can improve health. It is not only the complete food of nutrition, moreover it is possible to invigorating Qi and tonifying kidney, analgesic antidotal, have treatment and alleviating hypertension, heart disease, constipation, The effect of a variety of diseases such as insomnia;Eucalyptus honey with improve looks (can supply skin nutrient by skin have elasticity, can kill or Inhibit the bacterium for being attached to skin surface, moreover it is possible to eliminate the pigmentation of skin, promote epithelial tissue regeneration), antibacterial anti-inflammatory (bee Honey has stronger inhibiting effect to gram positive bacterias such as streptococcus, staphylococcus, corynebacterium diphtheriaes), promote digestion (lime tree honey pair Gastrointestinal function has adjustment effect, and gastric acid secretion can be made normal.Zoopery confirms that honey plays the role of enhancing enterocinesia, can show Write and shorten defecation time), it is antifatigue that (fructose in lime tree honey, honey glucose can be absorbed and used quickly, improve blood Battalion's situation;Honey is taken when human-body fatigue, can obviously eliminate fatigue symptom within 15 minutes) and other effects.
The above substance not only can be usually edible as health care product, can also be used as medicinal material use, is used in conjunction with or eats When, it can more mutually promote.Due to using cosmetics and skin care item improper, the skin of patient on the face is caused to have the residual of lead mercury, So as to cause skin problem, there are the skin agings problems such as dark yellow skin, long spot, long wrinkle in many people;Because many color make-ups produce More containing metal component in product and skin care item, some are used for a long time the Chemical metals such as leaded, mercury ingredient and mostly either add fragrance Color make-up or skin care item, these chemical components have the function of extinction, it is easy to cause the black group of skin.In addition, some Do not know that these products are easy to go bad at high temperature, it is outgoing that often skin care item are lost in vehicle heel row, after rotten product Skin can itch, one it is light-exposed will long color spot;Outer excessive chemical decortication:Some usually do some Chemopeels for whitening, The horny layer of epidermis of skin is allowed to be detached from, to be made The more the better, to be actually made too frequently, skin is more sensitive to light, becomes Drying, the sun shine once shine will play erythema, occur pigmentation instead than originally it is more serious, cause in skin lead mercury Poison.Therefore, a kind of whitening containing above-mentioned material is researched and developed, the heavy metals toxin such as internal lead, mercury, arsenic, the product of anti-aging are excluded The work urgent and important as one.
Summary of the invention
The first object of the present invention is to provide for a kind of compound metallothionein pill of lead discharging mercury, whitening, energy Exclude the heavy metals toxin such as internal lead, mercury, arsenic, anti-aging.
The second object of the present invention is to provide for preparing a kind of compound metallothionein pill of lead discharging mercury Method.
In order to realize the first purpose of aforementioned present invention, the technical scheme is that:A kind of compound metal of lead discharging mercury Sulfoprotein pill, it is characterised in that:By metallothionein, active collagen, calcium carbonate, vitamin B1, vitamin C, microcrystalline cellulose Element, magnesium stearate, fructus lycii, ginkgo leaf, Schisandra chinensis, semen sojae atricolor, Radix Astragali, Radix Angelicae Sinensis, physiological saline, dried lily bulb, Radix Glycyrrhizae, eucalyptus honey group At;The dosage of metallothionein is 0.5~2 parts by weight, and the dosage of active collagen is 1~3 parts by weight, and the dosage of calcium carbonate is 1 ~10 parts by weight, the dosage of vitamin B1 are 1~4 parts by weight, and ascorbic dosage is 1~5 parts by weight, microcrystalline cellulose Dosage is 1~10 parts by weight, and the dosage of magnesium stearate is 1~10 parts by weight, and the dosage of fructus lycii is 3~15 parts by weight, ginkgo leaf Dosage be 1~10 parts by weight, the dosage of Schisandra chinensis is 1~10 parts by weight, and the dosage of semen sojae atricolor is 3~10 parts by weight, Radix Astragali Dosage is 1~5 parts by weight, and the dosage of Radix Angelicae Sinensis is 3~8 parts by weight, and the dosage of physiological saline is 5~10 parts by weight, dried lily bulb Dosage is 1~15 parts by weight, and the dosage of Radix Glycyrrhizae is 5~15 parts by weight, and the dosage of eucalyptus honey is 30~63 parts by weight.
In the above-mentioned technical solutions, the dosage of metallothionein is 1~2 parts by weight, and the dosage of active collagen is 2~3 weights Part is measured, the dosage of calcium carbonate is 5~7 parts by weight, and the dosage of vitamin B1 is 2~4 parts by weight, and ascorbic dosage is 3~5 Parts by weight, the dosage of microcrystalline cellulose are 4~6 parts by weight, and the dosage of magnesium stearate is 6~8 parts by weight, and the dosage of fructus lycii is 5 ~7 parts by weight, the dosage of ginkgo leaf are 3~5 parts by weight, and the dosage of Schisandra chinensis is 2~4 parts by weight, and the dosage of semen sojae atricolor is 4~6 Parts by weight, the dosage of Radix Astragali are 3~5 parts by weight, and the dosage of Radix Angelicae Sinensis is 4~6 parts by weight, and the dosage of physiological saline is 5~7 weight Part, the dosage of dried lily bulb is 7~9 parts by weight, and the dosage of Radix Glycyrrhizae is 8~10 parts by weight, and the dosage of eucalyptus honey is 36~38 weight Part.
In the above-mentioned technical solutions, active collagen, ginkgo leaf, semen sojae atricolor, Radix Astragali, Radix Angelicae Sinensis weight ratio be 0.625 ﹕, 1 ﹕ 1.25 ﹕, 1 ﹕ 1.25.
In the above-mentioned technical solutions, the dosage of metallothionein is 1.5 parts by weight, and the dosage of active collagen is 2.5 weight Part, the dosage of calcium carbonate is 6 parts by weight, and the dosage of vitamin B1 is 3 parts by weight, and ascorbic dosage is 4 parts by weight, crystallite The dosage of cellulose is 5 parts by weight, and the dosage of magnesium stearate is 7 parts by weight, and the dosage of fructus lycii is 6 parts by weight, the use of ginkgo leaf Amount is 4 parts by weight, and the dosage of Schisandra chinensis is 3 parts by weight, and the dosage of semen sojae atricolor is 5 parts by weight, and the dosage of Radix Astragali is 4 parts by weight, when The dosage returned is 5 parts by weight, and the dosage of physiological saline is 6 parts by weight, and the dosage of dried lily bulb is 8 parts by weight, and the dosage of Radix Glycyrrhizae is 9 Parts by weight, the dosage of eucalyptus honey are 37 parts by weight.
In order to realize the second purpose of aforementioned present invention, the technical scheme is that:A kind of preparation lead discharging mercury Compound metallothionein pill method, it is characterised in that:Include the following steps:
Step 1:Add distilled water in iron by weight fructus lycii, ginkgo leaf, Schisandra chinensis, Radix Astragali, Radix Angelicae Sinensis, dried lily bulb, Radix Glycyrrhizae Heating boils tanning 7 hours into paste in pot, removes slag, is dried into crystalline solid, cooling, obtains compounding crystal;
Step 2:The semen sojae atricolor ground, physiological saline are uniformly mixed with the resulting crystal that compounds of step 1) by weight, 12~18h is placed at 25~35 DEG C, obtains mixed raw material;
Step 3:The resulting mixed raw material of step 2) is added in the eucalyptus honey of parts by weight, is uniformly mixed, at 30~40 DEG C Place 5~8h;
Step 4:The resulting mixed raw material of step 3) is added in the metallothionein of parts by weight, in 25~35 DEG C of room temperatures Celsius It is inside continuously stirring to uniformly mixed;
Step 5:By the resulting mixed raw material filtering containing eucalyptus honey of step 4), particulate matter is removed, parts by weight are added Active collagen, calcium carbonate, vitamin B1, vitamin C, microcrystalline cellulose, magnesium stearate are uniformly mixed to get compound metallothionein White cream;
Step 6:The resulting compound metallothionein cream of step 5) is subjected to vacuum dehydration;
Step 7:The dewatered compound metallothionein cream of step 5) is made to the pill of unified specification with pellet processing machine, is thrown Light to get a kind of lead discharging mercury compound metallothionein pill.
In the above-mentioned technical solutions, in step 2,16h is placed at 25~35 DEG C, obtains mixed raw material.
In the above-mentioned technical solutions, in step 3,7h is placed at 30~40 DEG C.
The eucalyptus honey is the eucalyptus honey of mature native.
The invention has the advantages that:
(1) present invention has good nutritive value and beautifying face and moistering lotion, excludes the heavy metals toxin, beauty such as internal lead, mercury, arsenic White, anti-aging effects;The effect for especially excluding the heavy metals such as internal lead, mercury, arsenic is preferable;
(2) present invention is in stable condition, and no lamination, in good taste, preparation temperature is not high, it is ensured that color does not become Change;
(3) present invention does not add preservative, is a kind of green natural product of health, and the body for being beneficial to user is strong Health;
(4) present invention long-term consumption can enhance human immunity, and have certain opsonic action to the skin of user;
(5) rationally, the ability that the metallothionein in the present invention removes free radical is stronger, and has very for present invention proportion Strong anti-oxidant activity;The function that metallothionein removes free radical makes it in anti-aging, anti-oxidant pressure and Apoptosis etc. It plays an important role in the process;Active collagen of the present invention can make skin keep original elasticity well, vitamin C have compared with Strong reproducibility;Polysaccharides that fructus lycii in the present invention contains, beta carotene are all the antioxidants of strength, add Chinese holly The synergistic effect of trace elements of selenium contained by Qi and vitamin E, antioxidant effect are preferable;Ginkgo leaf can increase sebum in the present invention The secretion of gland increases dry or aging skin by ruddy color;Schisandra chinensis can increase cellular immune function etc.;The present invention passes through Reasonable component and proportion achieve the effect that improve human endocrine, beautifying face and moistering lotion, nti-freckle and dispel yellow, wrinkle improvement effect.
2 grams every of compound metallothionein pill of a kind of lead discharging mercury of the present invention, instructions of taking are once in the morning and once at night, after the meal It takes.
Specific embodiment
Below with reference to the embodiment performance that the present invention will be described in detail, but they and do not constitute a limitation of the invention, It is only for example.Keep advantages of the present invention more clear by explanation simultaneously and is readily appreciated that.
A kind of compound metallothionein pill of lead discharging mercury, by metallothionein, active collagen, calcium carbonate, vitamin B1, Vitamin C, microcrystalline cellulose, magnesium stearate, fructus lycii, ginkgo leaf, Schisandra chinensis, semen sojae atricolor, Radix Astragali, Radix Angelicae Sinensis, physiological saline, lily Dry, Radix Glycyrrhizae, eucalyptus honey composition;The dosage of metallothionein is 0.5~2 parts by weight, and the dosage of active collagen is 1~3 parts by weight, The dosage of calcium carbonate is 1~10 parts by weight, and the dosage of vitamin B1 is 1~4 parts by weight, and ascorbic dosage is 1~5 weight Part, the dosage of microcrystalline cellulose is 1~10 parts by weight, and the dosage of magnesium stearate is 1~10 parts by weight, the dosage of fructus lycii is 3~ 15 parts by weight, the dosage of ginkgo leaf are 1~10 parts by weight, and the dosage of Schisandra chinensis is 1~10 parts by weight, the dosage of semen sojae atricolor is 3~ 10 parts by weight, the dosage of Radix Astragali are 1~5 parts by weight, and the dosage of Radix Angelicae Sinensis is 3~8 parts by weight, and the dosage of physiological saline is 5~10 Parts by weight, the dosage of dried lily bulb are 1~15 parts by weight, and the dosage of Radix Glycyrrhizae is 5~15 parts by weight, and the dosage of eucalyptus honey is 30~63 Parts by weight.
Further, the dosage of metallothionein is 1~2 parts by weight, and the dosage of active collagen is 2~3 parts by weight, carbonic acid The dosage of calcium is 5~7 parts by weight, and the dosage of vitamin B1 is 2~4 parts by weight, and ascorbic dosage is 3~5 parts by weight, micro- The dosage of crystalline cellulose is 4~6 parts by weight, and the dosage of magnesium stearate is 6~8 parts by weight, and the dosage of fructus lycii is 5~7 parts by weight, The dosage of ginkgo leaf is 3~5 parts by weight, and the dosage of Schisandra chinensis is 2~4 parts by weight, and the dosage of semen sojae atricolor is 4~6 parts by weight, Radix Astragali Dosage be 3~5 parts by weight, the dosage of Radix Angelicae Sinensis is 4~6 parts by weight, and the dosage of physiological saline is 5~7 parts by weight, dried lily bulb Dosage is 7~9 parts by weight, and the dosage of Radix Glycyrrhizae is 8~10 parts by weight, and the dosage of eucalyptus honey is 36~38 parts by weight.
Further, active collagen, ginkgo leaf, semen sojae atricolor, Radix Astragali, Radix Angelicae Sinensis weight ratio be 0.625 ﹕, 1 ﹕, 1.25 ﹕, 1 ﹕ 1.25.
Further, the dosage of metallothionein is 1.5 parts by weight, and the dosage of active collagen is 2.5 parts by weight, carbonic acid The dosage of calcium is 6 parts by weight, and the dosage of vitamin B1 is 3 parts by weight, and ascorbic dosage is 4 parts by weight, microcrystalline cellulose Dosage is 5 parts by weight, and the dosage of magnesium stearate is 7 parts by weight, and the dosage of fructus lycii is 6 parts by weight, and the dosage of ginkgo leaf is 4 weight Part, the dosage of Schisandra chinensis is 3 parts by weight, and the dosage of semen sojae atricolor is 5 parts by weight, and the dosage of Radix Astragali is 4 parts by weight, and the dosage of Radix Angelicae Sinensis is 5 parts by weight, the dosage of physiological saline are 6 parts by weight, and the dosage of dried lily bulb is 8 parts by weight, and the dosage of Radix Glycyrrhizae is 9 parts by weight, linden The dosage of tree honey is 37 parts by weight.
A kind of method of the compound metallothionein pill of system lead discharging mercury, includes the following steps:
Step 1:Add distilled water in iron by weight fructus lycii, ginkgo leaf, Schisandra chinensis, Radix Astragali, Radix Angelicae Sinensis, dried lily bulb, Radix Glycyrrhizae Heating boils tanning 7 hours into paste in pot, removes slag, is dried into crystalline solid, cooling, obtains compounding crystal;
Step 2:The semen sojae atricolor ground, physiological saline are uniformly mixed with the resulting crystal that compounds of step 1) by weight, 12~18h is placed at 25~35 DEG C, obtains mixed raw material;
Step 3:The resulting mixed raw material of step 2) is added in the eucalyptus honey of parts by weight, is uniformly mixed, at 30~40 DEG C Place 5~8h;
Step 4:The resulting mixed raw material of step 3) is added in the metallothionein of parts by weight, in 25~35 DEG C of room temperatures Celsius It is inside continuously stirring to uniformly mixed;
Step 5:By the resulting mixed raw material filtering containing eucalyptus honey of step 4), particulate matter is removed, parts by weight are added Active collagen, calcium carbonate, vitamin B1, vitamin C, microcrystalline cellulose, magnesium stearate are uniformly mixed to get compound metallothionein White cream;
Step 6:The resulting compound metallothionein cream of step 5) is subjected to vacuum dehydration;
Step 7:The dewatered compound metallothionein cream of step 5) is made to the pill of unified specification with pellet processing machine, is thrown Light to get a kind of lead discharging mercury compound metallothionein pill.
Further, in step 2,16h is placed at 25~35 DEG C, obtains mixed raw material.
Further, in step 3,7h is placed at 30~40 DEG C.
Embodiment 1
A kind of compound metallothionein pill of lead discharging mercury, by metallothionein, active collagen, calcium carbonate, vitamin B1, Vitamin C, microcrystalline cellulose, magnesium stearate, fructus lycii, ginkgo leaf, Schisandra chinensis, semen sojae atricolor, Radix Astragali, Radix Angelicae Sinensis, physiological saline, lily Dry, Radix Glycyrrhizae, eucalyptus honey composition;The dosage of metallothionein is 0.5 parts by weight, and the dosage of active collagen is 1 parts by weight, calcium carbonate Dosage be 1 parts by weight, the dosage of vitamin B1 is 4 parts by weight, and ascorbic dosage is 5 parts by weight, the use of microcrystalline cellulose Amount is 10 parts by weight, and the dosage of magnesium stearate is 10 parts by weight, and the dosage of fructus lycii is 15 parts by weight, and the dosage of ginkgo leaf is 1 weight Part is measured, the dosage of Schisandra chinensis is 10 parts by weight, and the dosage of semen sojae atricolor is 3 parts by weight, and the dosage of Radix Astragali is 5 parts by weight, the use of Radix Angelicae Sinensis Amount is 3 parts by weight, and the dosage of physiological saline is 10 parts by weight, and the dosage of dried lily bulb is 1 parts by weight, and the dosage of Radix Glycyrrhizae is 15 weight Part, the dosage of eucalyptus honey is 45 parts by weight.
A kind of method of the compound metallothionein pill of preparation lead discharging mercury, it is characterised in that:Including walking as follows Suddenly:
Step 1:Add distilled water in iron by weight fructus lycii, ginkgo leaf, Schisandra chinensis, Radix Astragali, Radix Angelicae Sinensis, dried lily bulb, Radix Glycyrrhizae Heating boils tanning 7 hours into paste in pot, removes slag, is dried into crystalline solid, cooling, obtains compounding crystal;
Step 2:The semen sojae atricolor ground, physiological saline are uniformly mixed with the resulting crystal that compounds of step 1) by weight, 12h is placed at 25~35 DEG C, obtains mixed raw material;
Step 3:The resulting mixed raw material of step 2) is added in the eucalyptus honey of parts by weight, is uniformly mixed, at 30~40 DEG C Place 8h;
Step 4:The resulting mixed raw material of step 3) is added in the metallothionein of parts by weight, in 25~35 DEG C of room temperatures Celsius It is inside continuously stirring to uniformly mixed;
Step 5:By the resulting mixed raw material filtering containing eucalyptus honey of step 4), particulate matter is removed, parts by weight are added Active collagen, calcium carbonate, vitamin B1, vitamin C, microcrystalline cellulose, magnesium stearate are uniformly mixed to get compound metallothionein White cream;
Step 6:The resulting compound metallothionein cream of step 5) is subjected to vacuum dehydration;
Step 7:The dewatered compound metallothionein cream of step 5) is made to the pill of unified specification with pellet processing machine, is thrown Light to get a kind of lead discharging mercury compound metallothionein pill.
Embodiment 2
A kind of compound metallothionein pill of lead discharging mercury, by metallothionein, active collagen, calcium carbonate, vitamin B1, Vitamin C, microcrystalline cellulose, magnesium stearate, fructus lycii, ginkgo leaf, Schisandra chinensis, semen sojae atricolor, Radix Astragali, Radix Angelicae Sinensis, physiological saline, lily Dry, Radix Glycyrrhizae, eucalyptus honey composition;The dosage of metallothionein is 2 parts by weight, and the dosage of active collagen is 3 parts by weight, calcium carbonate Dosage is 10 parts by weight, and the dosage of vitamin B1 is 1 parts by weight, and ascorbic dosage is 1 parts by weight, the use of microcrystalline cellulose Amount is 1 parts by weight, and the dosage of magnesium stearate is 1 parts by weight, and the dosage of fructus lycii is 3 parts by weight, and the dosage of ginkgo leaf is 6 weight Part, the dosage of Schisandra chinensis is 2 parts by weight, and the dosage of semen sojae atricolor is 8 parts by weight, and the dosage of Radix Astragali is 1 parts by weight, and the dosage of Radix Angelicae Sinensis is 8 parts by weight, the dosage of physiological saline are 9 parts by weight, and the dosage of dried lily bulb is 5 parts by weight, and the dosage of Radix Glycyrrhizae is 10 parts by weight, linden The dosage of tree honey is 63 parts by weight.
A kind of method of the compound metallothionein pill of preparation lead discharging mercury, it is characterised in that:Including walking as follows Suddenly:
Step 1:Add distilled water in iron by weight fructus lycii, ginkgo leaf, Schisandra chinensis, Radix Astragali, Radix Angelicae Sinensis, dried lily bulb, Radix Glycyrrhizae Heating boils tanning 7 hours into paste in pot, removes slag, is dried into crystalline solid, cooling, obtains compounding crystal;
Step 2:The semen sojae atricolor ground, physiological saline are uniformly mixed with the resulting crystal that compounds of step 1) by weight, 18h is placed at 25~35 DEG C, obtains mixed raw material;
Step 3:The resulting mixed raw material of step 2) is added in the eucalyptus honey of parts by weight, is uniformly mixed, at 30~40 DEG C Place 5h;
Step 4:The resulting mixed raw material of step 3) is added in the metallothionein of parts by weight, in 25~35 DEG C of room temperatures Celsius It is inside continuously stirring to uniformly mixed;
Step 5:By the resulting mixed raw material filtering containing eucalyptus honey of step 4), particulate matter is removed, parts by weight are added Active collagen, calcium carbonate, vitamin B1, vitamin C, microcrystalline cellulose, magnesium stearate are uniformly mixed to get compound metallothionein White cream;
Step 6:The resulting compound metallothionein cream of step 5) is subjected to vacuum dehydration;
Step 7:The dewatered compound metallothionein cream of step 5) is made to the pill of unified specification with pellet processing machine, is thrown Light to get a kind of lead discharging mercury compound metallothionein pill.
Embodiment 3
A kind of compound metallothionein pill of lead discharging mercury, by metallothionein, active collagen, calcium carbonate, vitamin B1, Vitamin C, microcrystalline cellulose, magnesium stearate, fructus lycii, ginkgo leaf, Schisandra chinensis, semen sojae atricolor, Radix Astragali, Radix Angelicae Sinensis, physiological saline, lily Dry, Radix Glycyrrhizae, eucalyptus honey composition;The dosage of metallothionein is 1.5 parts by weight, and the dosage of active collagen is 2.5 parts by weight, carbonic acid The dosage of calcium is 6 parts by weight, and the dosage of vitamin B1 is 3 parts by weight, and ascorbic dosage is 4 parts by weight, microcrystalline cellulose Dosage is 5 parts by weight, and the dosage of magnesium stearate is 7 parts by weight, and the dosage of fructus lycii is 6 parts by weight, and the dosage of ginkgo leaf is 4 weight Part, the dosage of Schisandra chinensis is 3 parts by weight, and the dosage of semen sojae atricolor is 5 parts by weight, and the dosage of Radix Astragali is 4 parts by weight, and the dosage of Radix Angelicae Sinensis is 5 parts by weight, the dosage of physiological saline are 6 parts by weight, and the dosage of dried lily bulb is 8 parts by weight, and the dosage of Radix Glycyrrhizae is 9 parts by weight, linden The dosage of tree honey is 37 parts by weight.
A kind of method of the compound metallothionein pill of preparation lead discharging mercury, it is characterised in that:Including walking as follows Suddenly:
Step 1:Add distilled water in iron by weight fructus lycii, ginkgo leaf, Schisandra chinensis, Radix Astragali, Radix Angelicae Sinensis, dried lily bulb, Radix Glycyrrhizae Heating boils tanning 7 hours into paste in pot, removes slag, is dried into crystalline solid, cooling, obtains compounding crystal;
Step 2:The semen sojae atricolor ground, physiological saline are uniformly mixed with the resulting crystal that compounds of step 1) by weight, 16h is placed at 25~35 DEG C, obtains mixed raw material;
Step 3:The resulting mixed raw material of step 2) is added in the eucalyptus honey of parts by weight, is uniformly mixed, at 30~40 DEG C Place 7h;
Step 4:The resulting mixed raw material of step 3) is added in the metallothionein of parts by weight, in 25~35 DEG C of room temperatures Celsius It is inside continuously stirring to uniformly mixed;
Step 5:By the resulting mixed raw material filtering containing eucalyptus honey of step 4), particulate matter is removed, parts by weight are added Active collagen, calcium carbonate, vitamin B1, vitamin C, microcrystalline cellulose, magnesium stearate are uniformly mixed to get compound metallothionein White cream;
Step 6:The resulting compound metallothionein cream of step 5) is subjected to vacuum dehydration;
Step 7:The dewatered compound metallothionein cream of step 5) is made to the pill of unified specification with pellet processing machine, is thrown Light to get a kind of lead discharging mercury compound metallothionein pill.
Embodiment 4
A kind of compound metallothionein pill of lead discharging mercury, by metallothionein, active collagen, calcium carbonate, vitamin B1, Vitamin C, microcrystalline cellulose, magnesium stearate, fructus lycii, ginkgo leaf, Schisandra chinensis, semen sojae atricolor, Radix Astragali, Radix Angelicae Sinensis, physiological saline, lily Dry, Radix Glycyrrhizae, eucalyptus honey composition;The dosage of metallothionein is 1 parts by weight, and the dosage of active collagen is 2 parts by weight, calcium carbonate Dosage is 5 parts by weight, and the dosage of vitamin B1 is 2 parts by weight, and ascorbic dosage is 5 parts by weight, the dosage of microcrystalline cellulose For 4 parts by weight, the dosage of magnesium stearate is 6 parts by weight, and the dosage of fructus lycii is 10 parts by weight, and the dosage of ginkgo leaf is 10 weight Part, the dosage of Schisandra chinensis is 8 parts by weight, and the dosage of semen sojae atricolor is 4 parts by weight, and the dosage of Radix Astragali is 2 parts by weight, and the dosage of Radix Angelicae Sinensis is 4 parts by weight, the dosage of physiological saline are 5 parts by weight, and 15 parts by weight of dosage of dried lily bulb, the dosage of Radix Glycyrrhizae is 5 parts by weight, lime tree The dosage of honey is 32 parts by weight.
A kind of method of the compound metallothionein pill of preparation lead discharging mercury, it is characterised in that:Including walking as follows Suddenly:
Step 1:Add distilled water in iron by weight fructus lycii, ginkgo leaf, Schisandra chinensis, Radix Astragali, Radix Angelicae Sinensis, dried lily bulb, Radix Glycyrrhizae Heating boils tanning 7 hours into paste in pot, removes slag, is dried into crystalline solid, cooling, obtains compounding crystal;
Step 2:The semen sojae atricolor ground, physiological saline are uniformly mixed with the resulting crystal that compounds of step 1) by weight, 13h is placed at 25~35 DEG C, obtains mixed raw material;
Step 3:The resulting mixed raw material of step 2) is added in the eucalyptus honey of parts by weight, is uniformly mixed, at 30~40 DEG C Place 6h;
Step 4:The resulting mixed raw material of step 3) is added in the metallothionein of parts by weight, in 25~35 DEG C of room temperatures Celsius It is inside continuously stirring to uniformly mixed;
Step 5:By the resulting mixed raw material filtering containing eucalyptus honey of step 4), particulate matter is removed, parts by weight are added Active collagen, calcium carbonate, vitamin B1, vitamin C, microcrystalline cellulose, magnesium stearate are uniformly mixed to get compound metallothionein White cream;
Step 6:The resulting compound metallothionein cream of step 5) is subjected to vacuum dehydration;
Step 7:The dewatered compound metallothionein cream of step 5) is made to the pill of unified specification with pellet processing machine, is thrown Light to get a kind of lead discharging mercury compound metallothionein pill.
Embodiment 5
A kind of compound metallothionein pill of lead discharging mercury, by metallothionein, active collagen, calcium carbonate, vitamin B1, Vitamin C, microcrystalline cellulose, magnesium stearate, fructus lycii, ginkgo leaf, Schisandra chinensis, semen sojae atricolor, Radix Astragali, Radix Angelicae Sinensis, physiological saline, lily Dry, Radix Glycyrrhizae, eucalyptus honey composition;The dosage of metallothionein is 1.5 parts by weight, and the dosage of active collagen is 3 parts by weight, calcium carbonate Dosage be 7 parts by weight, the dosage of vitamin B1 is 4 parts by weight, and ascorbic dosage is 3 parts by weight, the use of microcrystalline cellulose Amount is 6 parts by weight, and the dosage of magnesium stearate is 8 parts by weight, and the dosage of fructus lycii is 4 parts by weight, and the dosage of ginkgo leaf is 2 weight Part, the dosage of Schisandra chinensis is 1 parts by weight, and the dosage of semen sojae atricolor is 6 parts by weight, and the dosage of Radix Astragali is 5 parts by weight, and the dosage of Radix Angelicae Sinensis is 7 parts by weight, the dosage of physiological saline are 7 parts by weight, and the dosage of dried lily bulb is 10 parts by weight, and the dosage of Radix Glycyrrhizae is 8 parts by weight, linden The dosage of tree honey is 40 parts by weight.
Preparation method is the same as embodiment 3.
Comparative example 1
The compound metallothionein pill for comparing a kind of lead discharging mercury is given birth to by metallothionein, active collagen, calcium carbonate, dimension Plain B1, vitamin C, microcrystalline cellulose, magnesium stearate, fructus lycii, ginkgo leaf, Schisandra chinensis, semen sojae atricolor, Radix Astragali, Radix Angelicae Sinensis, physiological saline, Dried lily bulb, Radix Glycyrrhizae, eucalyptus honey composition;The dosage of metallothionein is 0.1 parts by weight, and the dosage of active collagen is 0.1 parts by weight, The dosage of calcium carbonate is 15 parts by weight, and the dosage of vitamin B1 is 5 parts by weight, and ascorbic dosage is 8 parts by weight, and crystallite is fine The dosage of dimension element is 15 parts by weight, and the dosage of magnesium stearate is 12 parts by weight, and the dosage of fructus lycii is 20 parts by weight, the use of ginkgo leaf Amount is 12 parts by weight, and the dosage of Schisandra chinensis is 11 parts by weight, and the dosage of semen sojae atricolor is 2 parts by weight, and the dosage of Radix Astragali is 6 parts by weight, The dosage of Radix Angelicae Sinensis is 1 parts by weight, and the dosage of physiological saline is 15 parts by weight, and the dosage of dried lily bulb is 18 parts by weight, the use of Radix Glycyrrhizae Amount is 16 parts by weight, and the dosage of eucalyptus honey is 48 parts by weight.
Preparation method is the same as embodiment 3.
Comparative example 2
A kind of compound metallothionein pill of lead discharging mercury, by metallothionein, calcium carbonate, vitamin B1, vitamin C, Microcrystalline cellulose, magnesium stearate, fructus lycii, Schisandra chinensis, Radix Angelicae Sinensis, physiological saline, dried lily bulb, Radix Glycyrrhizae, eucalyptus honey composition;Metallothionein White dosage is 0.05 parts by weight, and the dosage of calcium carbonate is 8 parts by weight, and the dosage of vitamin B1 is 3 parts by weight, ascorbic Dosage is 1 parts by weight, and the dosage of microcrystalline cellulose is 10 parts by weight, and the dosage of magnesium stearate is 10 parts by weight, the dosage of fructus lycii For 18 parts by weight, the dosage of Schisandra chinensis is 12 parts by weight, and the dosage of physiological saline is 15 parts by weight, and the dosage of dried lily bulb is 18 weights Part is measured, the dosage of Radix Glycyrrhizae is 20 parts by weight, and the dosage of eucalyptus honey is 49 parts by weight.
The method for preparing a kind of compound metallothionein pill of above-mentioned lead discharging mercury, includes the following steps:
Step 1:Add distilled water to heat in iron pan by weight fructus lycii, ginkgo leaf, Schisandra chinensis, dried lily bulb, Radix Glycyrrhizae to boil It removes slag at paste, is dried into crystalline solid within boiling tanning 7 hours, it is cooling, obtain compounding crystal;
Step 2:Physiological saline is uniformly mixed with the resulting crystal that compounds of step 1) by weight, is transferred at 25~35 DEG C 13h is set, mixed raw material is obtained;
Step 3:The resulting mixed raw material of step 2) is added in the eucalyptus honey of parts by weight, is uniformly mixed, at 30~40 DEG C Place 6h;
Step 4:The resulting mixed raw material of step 3) is added in the metallothionein of parts by weight, in 25~35 DEG C of room temperatures Celsius It is inside continuously stirring to uniformly mixed;
Step 5:By the resulting mixed raw material filtering containing eucalyptus honey of step 4), particulate matter is removed, parts by weight are added Calcium carbonate, vitamin B1, vitamin C, microcrystalline cellulose, magnesium stearate are uniformly mixed to get compound metallothionein cream;
Step 6:The resulting compound metallothionein cream of step 5) is subjected to vacuum dehydration;
Step 7:The dewatered compound metallothionein cream of step 5) is made to the pill of unified specification with pellet processing machine, is thrown Light to get a kind of lead discharging mercury compound metallothionein pill.
Choosing dark yellow 110 skins, canthus, cheek has color spot, skin to have obvious wrinkle, and the face that skin is obviously dried is asked Topic women tests, and subjects are the oldest 19~40 years old;11 groups are randomly divided into, every group of 10 people.
Blank control is the compound metallothionein pill Related product for not taking a kind of lead discharging mercury, other are early daily respectively Evening respectively takes an a kind of compound metallothionein pill for lead discharging mercury, and three months as a treatment course, takes institute after a course for the treatment of The result obtained is as shown in table 1 below:
1 embodiment of table and comparative example effect
In upper table, facial problem removal ratio is 90 or more to be considered as that whitening spot-removing wrinkle improvement effect is good, and facial problem is gone Except ratio is that 80~90 to be considered as whitening spot-removing wrinkle improvement effect good, facial problem removal ratio is higher than 60%, and to be considered as effect general;From Upper table can be seen that addition ginkgo leaf, semen sojae atricolor, Radix Astragali:A kind of compound metallothionein pill of lead discharging mercury of Radix Angelicae Sinensis has more preferably Whitening spot-removing wrinkle improvement effect, and the weight ratio of active collagen, ginkgo leaf, semen sojae atricolor, Radix Astragali, Radix Angelicae Sinensis be 0.625 ﹕, 1 ﹕, 1.25 ﹕ When 1 ﹕ 1.25, a kind of compound metallothionein pill beauty of a kind of lead discharging mercury of compound metallothionein pill of lead discharging mercury obtained White nti-freckle wrinkle improvement effect is best, i.e. heavy metals toxin, the whitening and anti-aging effect such as beautifying face and moistering lotion, the internal lead of exclusion, mercury, arsenic is good.
Other unaccounted parts belong to the prior art.

Claims (7)

1. a kind of compound metallothionein pill of lead discharging mercury, it is characterised in that:By metallothionein, active collagen, calcium carbonate, Vitamin B1, vitamin C, microcrystalline cellulose, magnesium stearate, fructus lycii, ginkgo leaf, Schisandra chinensis, semen sojae atricolor, Radix Astragali, Radix Angelicae Sinensis, physiology salt Water, dried lily bulb, Radix Glycyrrhizae, eucalyptus honey composition;The dosage of metallothionein is 0.5~2 parts by weight, and the dosage of active collagen is 1~3 Parts by weight, the dosage of calcium carbonate are 1~10 parts by weight, and the dosage of vitamin B1 is 1~4 parts by weight, and ascorbic dosage is 1 ~5 parts by weight, the dosage of microcrystalline cellulose are 1~10 parts by weight, and the dosage of magnesium stearate is 1~10 parts by weight, the use of fructus lycii Amount is 3~15 parts by weight, and the dosage of ginkgo leaf is 1~10 parts by weight, and the dosage of Schisandra chinensis is 1~10 parts by weight, the use of semen sojae atricolor Amount is 3~10 parts by weight, and the dosage of Radix Astragali is 1~5 parts by weight, and the dosage of Radix Angelicae Sinensis is 3~8 parts by weight, the dosage of physiological saline For 5~10 parts by weight, the dosage of dried lily bulb is 1~15 parts by weight, and the dosage of Radix Glycyrrhizae is 5~15 parts by weight, the dosage of eucalyptus honey For 30~63 parts by weight.
2. a kind of compound metallothionein pill of lead discharging mercury according to claim 1, it is characterised in that:Metallothionein Dosage be 1~2 parts by weight, the dosage of active collagen is 2~3 parts by weight, and the dosage of calcium carbonate is 5~7 parts by weight, vitamin The dosage of B1 is 2~4 parts by weight, and ascorbic dosage is 3~5 parts by weight, and the dosage of microcrystalline cellulose is 4~6 parts by weight, The dosage of magnesium stearate is 6~8 parts by weight, and the dosage of fructus lycii is 5~7 parts by weight, and the dosage of ginkgo leaf is 3~5 parts by weight, five The dosage of taste is 2~4 parts by weight, and the dosage of semen sojae atricolor is 4~6 parts by weight, and the dosage of Radix Astragali is 3~5 parts by weight, the use of Radix Angelicae Sinensis Amount is 4~6 parts by weight, and the dosage of physiological saline is 5~7 parts by weight, and the dosage of dried lily bulb is 7~9 parts by weight, the dosage of Radix Glycyrrhizae For 8~10 parts by weight, the dosage of eucalyptus honey is 36~38 parts by weight.
3. a kind of compound metallothionein pill of lead discharging mercury according to claim 2, it is characterised in that:Active collagen, Ginkgo leaf, semen sojae atricolor, Radix Astragali, Radix Angelicae Sinensis weight ratio be 0.625 ﹕, 1 ﹕, 1.25 ﹕, 1 ﹕ 1.25.
4. a kind of compound metallothionein pill of lead discharging mercury according to claim 3, it is characterised in that:Metallothionein Dosage be 1.5 parts by weight, the dosage of active collagen is 2.5 parts by weight, and the dosage of calcium carbonate is 6 parts by weight, vitamin B1 Dosage is 3 parts by weight, and ascorbic dosage is 4 parts by weight, and the dosage of microcrystalline cellulose is 5 parts by weight, the dosage of magnesium stearate For 7 parts by weight, the dosage of fructus lycii is 6 parts by weight, and the dosage of ginkgo leaf is 4 parts by weight, and the dosage of Schisandra chinensis is 3 parts by weight, black The dosage of beans is 5 parts by weight, and the dosage of Radix Astragali is 4 parts by weight, and the dosage of Radix Angelicae Sinensis is 5 parts by weight, and the dosage of physiological saline is 6 weights Part is measured, the dosage of dried lily bulb is 8 parts by weight, and the dosage of Radix Glycyrrhizae is 9 parts by weight, and the dosage of eucalyptus honey is 37 parts by weight.
5. preparing a kind of side of the compound metallothionein pill of lead discharging mercury described in any claim in claim 1-4 Method, it is characterised in that:Include the following steps:
Step 1:Add distilled water in iron pan by weight fructus lycii, ginkgo leaf, Schisandra chinensis, Radix Astragali, Radix Angelicae Sinensis, dried lily bulb, Radix Glycyrrhizae Heating boils tanning 7 hours into paste, removes slag, is dried into crystalline solid, cooling, obtains compounding crystal;
Step 2:The semen sojae atricolor ground, physiological saline and the resulting crystal that compounds of step 1) are uniformly mixed by weight, 25~ 12~18h is placed at 35 DEG C, obtains mixed raw material;
Step 3:The resulting mixed raw material of step 2) is added in the eucalyptus honey of parts by weight, is uniformly mixed, places 5 at 30~40 DEG C ~8h;
Step 4:The resulting mixed raw material of step 3) is added in the metallothionein of parts by weight, is connected in 25~35 DEG C of room temperatures Celsius It is continuous to stir to uniformly mixed;
Step 5:By the resulting mixed raw material filtering containing eucalyptus honey of step 4), particulate matter is removed, the activity of parts by weight is added Collagen, calcium carbonate, vitamin B1, vitamin C, microcrystalline cellulose, magnesium stearate are uniformly mixed to get compound metallothionein Cream;
Step 6:The resulting compound metallothionein cream of step 5) is subjected to vacuum dehydration;
Step 7:The dewatered compound metallothionein cream of step 5) is made to the pill of unified specification with pellet processing machine, is polished, i.e., Obtain a kind of compound metallothionein pill of lead discharging mercury.
6. a kind of method of the compound metallothionein pill according to claim 5 for preparing lead discharging mercury, it is characterised in that: In step 2,16h is placed at 25~35 DEG C, obtains mixed raw material.
7. a kind of method of the compound metallothionein pill according to claim 6 for preparing lead discharging mercury, it is characterised in that: In step 3,7h is placed at 30~40 DEG C.
CN201810953675.6A 2018-08-21 2018-08-21 A kind of compound metallothionein pill of lead discharging mercury and preparation method thereof Pending CN108837145A (en)

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