CN107080811A

CN107080811A - Treat Chinese medicine preparation of whelk and preparation method thereof

Info

Publication number: CN107080811A
Application number: CN201710319934.5A
Authority: CN
Inventors: 李宏伟; 徐石清; 王松; 童玲玲; 范婷婷; 严冰倩
Original assignee: WUHAN JUN AN PHARMACEUTICAL Co Ltd
Current assignee: WUHAN JUN AN PHARMACEUTICAL Co Ltd
Priority date: 2017-05-09
Filing date: 2017-05-09
Publication date: 2017-08-22

Abstract

The invention discloses a kind of Chinese medicine preparation for treating whelk and preparation method thereof, the main raw material included in parts by weight：100 200 parts of the red sage root, 180 250 parts of Asian puccoon, 80 120 parts of Exocarpium Citri Rubrum, 50 120 parts of prepared RHIZOMA PINELLIZE without adju-vant, 100 200 parts of Poria cocos, 120 180 parts of hawthorn, 30 90 parts of arisaema cum bile, 80 120 parts of spina gleditsiae, 50 150 parts of balloonflower root, 180 250 parts of coix seed, 180 250 parts of oriental wormwood, 120 220 parts of RADIX POLYGONI MULTIFLORI PREPARATA, 100 150 parts of the radix paeoniae rubrathe, 100 200 parts of the root of herbaceous peony, 100 200 parts of the dried rhizome of rehmannia, 180 250 parts of honeysuckle, 180 250 parts of dandelion, 180 250 parts of Chinese violet, 100 160 parts of the capsule of weeping forsythia, 80 120 parts of the coptis, 100 160 parts of chrysanthemum indicum, 100 200 parts of the Radix Astragali, 30 90 parts of 100 200 parts of Radix Angelicae Sinensis and radix glycyrrhizae.The Chinese medicine preparation of present invention treatment whelk is convenient for carrying, it is easy to is taken, is had no toxic side effect, cure rate is high.

Description

Treat Chinese medicine preparation of whelk and preparation method thereof

Technical field

The present invention relates to technical field of Chinese medicine, more particularly to a kind of Chinese medicine preparation for treating whelk and its preparation side Method.

Background technology

Whelk is acne, is due to that the grease row inside hair follicle and sebum adenemphraxis, hair follicle does not come out, caused by inflammation A kind of chronic inflammation skin disease, clinical is main performance with Whiteheads, warts, tumour etc., and hebetic men and women is main hair Sick colony, part adult and married person can also suffer from this disease, and its incidence of disease increases year by year in recent years, and age of onset is in expansion Trend, investigation shows：The people that there is 80%-90% in the whole nation suffered from this disease, because whelk directly influences the appearance of patient, Physiology and mental health to patient bring strong influence, therefore the research for treating whelk is significant, city The medicine of the ointment class for the treatment of whelk on field, cures the symptoms, not the disease, and wanting healing whelk will also fundamentally understand the cause of disease, Suit the remedy to the case, the traditional Chinese medical science thinks that the pathogenesis of whelk has four：Lung channel blood-head, stomach accumulated heat, the deficiency of the kidney yin, internal heat are partially prosperous；Carry For a kind of Chinese medicine composition suited the medicine to the illness with pathogenesis, it is necessary fundamentally to cure whelk.

The content of the invention

It is an object of the invention to solve at least the above, and provide the advantage that at least will be described later.

It is a still further object of the present invention to provide a kind of Chinese medicine preparation for treating whelk and preparation method thereof, the Chinese medicine Preparation is convenient for carrying, it is easy to taken, and is had no toxic side effect, and cure rate is high and does not recur.

In order to realize that there is provided a kind of Chinese medicine system for treating whelk according to object of the present invention and further advantage Agent, the main raw material included in parts by weight：

100-200 parts of the red sage root, 180-250 parts of Asian puccoon, 80-120 parts of Exocarpium Citri Rubrum, 50-120 parts of prepared RHIZOMA PINELLIZE without adju-vant, Poria cocos 100-200 Part, 120-180 parts of hawthorn, 30-90 parts of arisaema cum bile, 80-120 parts of spina gleditsiae, 50-150 parts of balloonflower root, 180-250 parts of coix seed, oriental wormwood 180-250 parts, 120-220 parts of RADIX POLYGONI MULTIFLORI PREPARATA, 100-150 parts of the radix paeoniae rubrathe, 100-200 parts of the root of herbaceous peony, 100-200 parts of the dried rhizome of rehmannia, honeysuckle 180-250 parts, 180-250 parts of dandelion, 180-250 parts of Chinese violet, 100-160 parts of the capsule of weeping forsythia, 80-120 parts of the coptis, chrysanthemum indicum 30-90 parts of 100-160 parts, 100-200 parts of the Radix Astragali, 100-200 parts of Radix Angelicae Sinensis and radix glycyrrhizae.

Preferably, the Chinese medicine preparation of the treatment whelk, in addition to the following raw material in parts by weight：Manyflower Gueldenstaedtid Herb 100-160 parts, 30-90 parts of the wind-weed, 80-120 parts of scutellaria, 30-90 parts of lily, 50-150 parts of matrimony vine, 100-160 parts of field pennycress, 120-220 parts of the tuber of dwarf lilyturf, 120-180 parts of the stem pith of the rice-paper plant, 50-150 parts of radix scrophulariae, 80-120 parts of subprostrate sophora, fresh peppermint 30-90 parts and white 100-200 parts of father-in-law of head.

Preferably, the Chinese medicine preparation of the treatment whelk, including the following raw material in parts by weight：150 parts of the red sage root, 210 parts of Asian puccoon, 100 parts of Exocarpium Citri Rubrum, 90 parts of prepared RHIZOMA PINELLIZE without adju-vant, 150 parts of Poria cocos, 150 parts of hawthorn, 60 parts of arisaema cum bile, 100 parts of spina gleditsiae, balloonflower root 100 parts, 200 parts of coix seed, 200 parts of oriental wormwood, 180 parts of RADIX POLYGONI MULTIFLORI PREPARATA, 120 parts of the radix paeoniae rubrathe, 150 parts of the root of herbaceous peony, 150 parts of the dried rhizome of rehmannia, honeysuckle 200 parts, 200 parts of dandelion, 200 parts of Chinese violet, 120 parts of the capsule of weeping forsythia, 100 parts of the coptis, 120 parts of chrysanthemum indicum, 150 parts of the Radix Astragali, when Return 150 parts, 60 parts of radix glycyrrhizae, 120 parts of Manyflower Gueldenstaedtid Herb, 60 parts of the wind-weed, 100 parts of scutellaria, 60 parts of lily, 100 parts of matrimony vine, field pennycress 120 150 parts of part, 180 parts of the tuber of dwarf lilyturf, 150 parts of the stem pith of the rice-paper plant, 100 parts of radix scrophulariae, 100 parts of subprostrate sophora, 60 parts of fresh peppermint and the Chinese bulbul.

A kind of preparation method for the Chinese medicine preparation for treating whelk, comprises the following steps：

Step 1, the red sage root decocted 2 times, add 8-12 times of water for the first time, the water for adding 6-10 times second is each pan-fried 1.5-3h is boiled, merges decoction twice and crosses 100 eye mesh screens, concentrate, add isometric mass concentration and stirred for 70-80% ethanol 20-40min, stands, and reclaims ethanol, concentrates, concentrate is spray-dried again obtains dry extract, standby.

Step 2, Asian puccoon, Exocarpium Citri Rubrum, prepared RHIZOMA PINELLIZE without adju-vant, Poria cocos, hawthorn, arisaema cum bile, spina gleditsiae, balloonflower root, coix seed are weighed by weight And oriental wormwood, refluxing extraction 2 times, 6-10 times of water is added every time, and obtained extract solution is concentrated under reduced pressure, and adds isometric matter Amount concentration is 60-80% ethanol, is stood, and reclaims ethanol, is concentrated to give the first concentrate, standby.

Step 3, weigh by weight the tuber of multiflower knotweed, the radix paeoniae rubrathe, the root of herbaceous peony, radix rehmanniae recen, honeysuckle, dandelion, Chinese violet, the capsule of weeping forsythia, The coptis, chrysanthemum indicum, the Radix Astragali, Radix Angelicae Sinensis and radix glycyrrhizae, decoct twice, wherein the fleece-flower root, the root of herbaceous peony, the radix paeoniae rubrathe and radix rehmanniae recen smash grinding Into the water of coarse powder, for the first time 8-12 times of addition, temperature soaks 1-3h at 70-90 DEG C, decocts 0.5-1.5h, second of 6-10 times of addition Water, decocts 1-3h, decoction will merge filtering twice and flow back to obtain the second concentrate, standby.

Step 4, dry extract, the first concentrate and the second concentrate mixed add polyethylene glycol and mix, pill obtains institute State the Chinese medicine preparation for the treatment of whelk.

Preferably, the preparation method of the Chinese medicine preparation of the treatment whelk, is additionally included in dry extract in step 4 Powder, the first concentrate, the second concentrate and the mixing of the 3rd concentrate add polyethylene glycol and mixed, and pill obtains the treatment whelk Chinese medicine preparation；The preparation method of 3rd concentrate is as follows：

Manyflower Gueldenstaedtid Herb, the wind-weed, scutellaria, lily, matrimony vine, field pennycress, the tuber of dwarf lilyturf, the stem pith of the rice-paper plant, radix scrophulariae, mountain beans are weighed by weight Root, fresh peppermint and the Chinese bulbul, are decocted 2 times, and 8-12 times of water is added for the first time, and the water of second of 6-10 times of addition is decocted every time 1.5-3h is boiled, merges medical filtration twice, concentration adds isometric mass concentration and stirs 20-40min for 80-90% ethanol, Stand, reclaim ethanol, be concentrated to give the 3rd concentrate.

Preferably, the preparation method of the Chinese medicine preparation of the treatment whelk, pelletizing process is as follows described in step 4：

Dry extract, the first concentrate, the second concentrate and the 3rd concentrate are mixed and add polyethylene glycol mixing, insulation At 60-100 DEG C, the liquid paraffin of -3--8 DEG C of instillation removes liquid paraffin, selects ball, produces the Chinese medicine system of the treatment whelk Agent.

Preferably, it is described treatment whelk Chinese medicine preparation preparation method, add polyethylene glycol parts by weight be 5000-7000 parts, dry extract, the first concentrate, the mixture of the second concentrate and the 3rd concentrate and polyethylene glycol it is mixed Composition and division in a proportion example is 1-2:5-8.

Preferably, spray drying parameters are in the preparation method of the Chinese medicine preparation of the treatment whelk, step 1：Enter Draught temperature is 150-200 DEG C, and air outlet temperature is 60-90 DEG C.

The present invention at least includes following beneficial effect：

The present invention is using the red sage root, Asian puccoon, Exocarpium Citri Rubrum, prepared RHIZOMA PINELLIZE without adju-vant, Poria cocos, hawthorn, arisaema cum bile, spina gleditsiae, balloonflower root, coix seed, mattress Old, RADIX POLYGONI MULTIFLORI PREPARATA, the radix paeoniae rubrathe, the root of herbaceous peony, the dried rhizome of rehmannia, honeysuckle, dandelion, Chinese violet, the capsule of weeping forsythia, the coptis, chrysanthemum indicum, the Radix Astragali, Radix Angelicae Sinensis with And radix glycyrrhizae compounding constitutes preparation prescription, have effects that clearing heat and detoxicating, logical internal organs expels the heat-evil, dispels grease, and the nontoxic pair of above-mentioned medicinal material Effect, will not cause any adverse reaction；Wherein, the red sage root, promoting blood circulation for regulating menstruation, stasis-dispelling and pain-killing, cool blood to disappear carbuncle, relieving restlessness that clears away heart-fire, blood-nourishing Calm the nerves；Asian puccoon, cooling and activating blood, the effect for promoting eruption of detoxifying；Exocarpium Citri Rubrum, eliminating dampness and eliminating phlegm, qi-regulating helps digestion；Prepared RHIZOMA PINELLIZE without adju-vant is eliminating dampness and eliminating phlegm；Fu Siberian cocklebur, invigorating the spleen, excreting dampness, mental-tranquilization；Hawthorn, promoting digestion and removing indigestion, promoting blood circulation to remove blood stasis；Arisaema cum bile, clearing heat and eliminating phlegm effect can be fixed with ceases wind It is frightened；Spina gleditsiae, eliminating evil wind, toxin expelling are dispelled purulence；Balloonflower root, opens facilitaing lung gas, eliminating the phlegm apocenosis；Coix seed, dries except wind, clearing away heat and eliminating pus, eliminating impediment Analgesic；Oriental wormwood, hepatic cholagogic；RADIX POLYGONI MULTIFLORI PREPARATA, filling liver kidney, benefiting essence-blood, the turbid lipid-loweringing of change；The radix paeoniae rubrathe, clearing heat and cooling blood, blood stasis removing analgesic；The root of herbaceous peony, Nourishing blood and liver, slow middle analgesic；The dried rhizome of rehmannia, clearing heat and cooling blood, yin-nourishing, promotes the production of body fluid；Honeysuckle, dandelion, it is clearing heat and detoxicating, clearing away and dispersing lung-heat, anti- Infection；The coptis, honeysuckle, chrysanthemum indicum, Chinese violet, are also clearing heat and detoxicating good medicine, and with stronger anti-aging, antibacterial and Suppress the pharmacological action of dermatophyte growth, local microcirculation can be improved by the treatment such as antimicrobial antiphlogistic so that Inflammatory substances Ooze out reduction；The capsule of weeping forsythia, heat-clearing, removing toxic substances, dissipating bind, detumescence；The Radix Astragali, invigorating qi for consolidating superficies, inducing diuresis for removing edema, detoxification, myogenic；Radix Angelicae Sinensis, enriches blood With blood, menstruction regulating and pain relieving, moisturize laxation；Radix glycyrrhizae, it is clearing heat and detoxicating, moisten the lung and relieve the cough, coordinating the drug actions of a prescription.

Chinese medicine preparation of the present invention can play good therapeutic effect, and treatment whelk expense is low, the Chinese medicine group Compound is natural medicine, is had no adverse reaction and toxic side effect, and pharmaceutical composition of the present invention effect is comprehensive, and clinical drug effect is more It is good, the compliance and quality of life of patient is significantly improved, is not recurred, clinical cure rate reaches 95%, is contrasted existing The mode of other drugs treatment, curative effect is notable.

Further advantage, target and the feature of the present invention embodies part by following explanation, and part will also be by this The research and practice of invention and be understood by the person skilled in the art.

Brief description of the drawings

Fig. 1 is the process chart of the preparation method of the Chinese medicine preparation for the treatment of whelk of the present invention.

Embodiment

The present invention is described in further detail below in conjunction with the accompanying drawings, to make those skilled in the art with reference to specification text Word can be implemented according to this.

It should be appreciated that such as " having ", "comprising" and " comprising " term used herein do not allot one or many The presence or addition of individual other elements or its combination.

The present invention provides a kind of Chinese medicine preparation for treating whelk, wherein, the main raw material included in parts by weight：

In such scheme, Coryza Treated by Syndrome Differentiation is carried out using Chinese medicinal formulae heat-clearing disinfectant soup, with the red sage root, Asian puccoon, Exocarpium Citri Rubrum, clear half Summer, Poria cocos, hawthorn, arisaema cum bile, spina gleditsiae, balloonflower root, coix seed, oriental wormwood, RADIX POLYGONI MULTIFLORI PREPARATA, the radix paeoniae rubrathe, the root of herbaceous peony, the dried rhizome of rehmannia, honeysuckle, Pu Gong English, Chinese violet, the capsule of weeping forsythia, the coptis, chrysanthemum indicum, the Radix Astragali, Radix Angelicae Sinensis and radix glycyrrhizae are main ingredient, expel the heat-evil, dispel with clearing heat and detoxicating, logical internal organs Except effect of grease, and above-mentioned medicinal material has no toxic side effect, and will not cause any adverse reaction；Wherein, the red sage root, promoting blood circulation for regulating menstruation is dispelled The stasis of blood is relieved pain, cool blood to disappear carbuncle, relieving restlessness that clears away heart-fire, nourishing blood and tranquilization；Asian puccoon, cooling and activating blood, the effect for promoting eruption of detoxifying；Exocarpium Citri Rubrum, eliminating dampness and eliminating phlegm, Qi-regulating helps digestion；Prepared RHIZOMA PINELLIZE without adju-vant is eliminating dampness and eliminating phlegm；Poria cocos, invigorating the spleen, excreting dampness, mental-tranquilization；Hawthorn, promoting digestion and removing indigestion, promoting blood circulation to remove blood stasis；Courage south Star, clearing heat and eliminating phlegm effect can be with dispelling wind and relieving convulsion；Spina gleditsiae, eliminating evil wind, toxin expelling are dispelled purulence；Balloonflower root, opens facilitaing lung gas, eliminating the phlegm apocenosis；The heart of a lotus seed The seed of jog's tears, dries except wind, clearing away heat and eliminating pus, eliminating impediment and relieving pain；Oriental wormwood, hepatic cholagogic；RADIX POLYGONI MULTIFLORI PREPARATA, filling liver kidney, benefiting essence-blood, the turbid lipid-loweringing of change； The radix paeoniae rubrathe, clearing heat and cooling blood, blood stasis removing analgesic；The root of herbaceous peony, nourishing blood and liver, slow middle analgesic；The dried rhizome of rehmannia, clearing heat and cooling blood, yin-nourishing, promotes the production of body fluid；Honeysuckle, Dandelion, it is clearing heat and detoxicating, clearing away and dispersing lung-heat, anti-infective；The coptis, honeysuckle, chrysanthemum indicum, Chinese violet, are also clearing heat and detoxicating good Medicine；The capsule of weeping forsythia, heat-clearing, removing toxic substances, dissipating bind, detumescence；The Radix Astragali, invigorating qi for consolidating superficies, inducing diuresis for removing edema, detoxification, myogenic；Radix Angelicae Sinensis, benefiting blood and regulating blood circulation, tune Meridian and relieving pain, moisturize laxation；Radix glycyrrhizae, it is clearing heat and detoxicating, moisten the lung and relieve the cough, coordinating the drug actions of a prescription；Fang Zhong：Asian puccoon has cooling and activating blood, removing toxic substances Effect of promoting eruption, can control blood-heat and toxin exuberance, atropurpureus macula, measles without adequate eruption, blood-head tells nosebleed, eczema, scald etc., honeysuckle, Pu Public English is clearing heat and detoxicating, clearing away and dispersing lung-heat, anti-infective；The coptis and honeysuckle heat-clearing, chrysanthemum indicum, Chinese violet are clearing heat and detoxicating good Medicine, shows according to modern pharmacological research, and honeysuckle, dandelion, Chinese violet etc. have stronger anti-aging, antibacterial and suppress skin The pharmacological action of fungi growth, and local microcirculation can be improved by the treatment such as antimicrobial antiphlogistic so that Inflammatory substances ooze out Reduce, good therapeutic effect can be played, using this side treatment whelk expense is low, effect is good, have no toxic side effect, Huan Zheyi In receiving.

In one preferred scheme, the Chinese medicine preparation of the treatment whelk, in addition to the following raw material in parts by weight：Sweet tea 100-160 parts of Chinese violet, 30-90 parts of the wind-weed, 80-120 parts of scutellaria, 30-90 parts of lily, 50-150 parts of matrimony vine, field pennycress 100-160 Part, 120-220 parts of the tuber of dwarf lilyturf, 120-180 parts of the stem pith of the rice-paper plant, 50-150 parts of radix scrophulariae, 80-120 parts of subprostrate sophora, fresh peppermint 30-90 parts with And 100-200 parts of the Chinese bulbul.

In such scheme, Manyflower Gueldenstaedtid Herb, the wind-weed, scutellaria, lily, matrimony vine, field pennycress, Mai Men are added again in Chinese medicine preparation Supplemented by winter, the stem pith of the rice-paper plant, radix scrophulariae, subprostrate sophora, fresh peppermint and the Chinese bulbul, collaboration facilitation is given full play to main ingredient, can significantly be carried Rise the curative effect for the treatment of whelk；Wherein, Manyflower Gueldenstaedtid Herb, clearing heat and detoxicating, cool blood detumescence；The wind-weed, clearing lung and eliminating phlegm, enriching yin and nourishing kidney；Scutellaria, Heat-clearing and damp-drying drug, detoxicating functions；Lily, tonifying middle-Jiao and Qi, Yin nourishing and lung moistening；Field pennycress, the clearing heat and detoxicating, carbuncle that disappears apocenosis, stasis-dispelling and pain-killing；Wheat Men Dong, Yin nourishing and lung moistening, relieving restlessness that clears away heart-fire；The stem pith of the rice-paper plant, cold dispelling expels the heat-evil, strengthening the spleen and stomach；Radix scrophulariae, nourishing Yin and falling fire, removing toxic substances；Subprostrate sophora, heat-clearing solution Poison；Fresh peppermint, dispelling wind and heat from the body, the malicious promoting eruption of a surname；The Chinese bulbul, it is clearing heat and detoxicating, remove heat from the blood and relieve diarrhea, antibacterial；Above-mentioned medicinal material is abundant to main ingredient Collaboration facilitation is played, the curative effect for the treatment of whelk can be obviously improved.

In one preferred scheme, the Chinese medicine preparation of the treatment whelk, including the following raw material in parts by weight：The red sage root 150 parts, 210 parts of Asian puccoon, 100 parts of Exocarpium Citri Rubrum, 90 parts of prepared RHIZOMA PINELLIZE without adju-vant, 150 parts of Poria cocos, 150 parts of hawthorn, 60 parts of arisaema cum bile, spina gleditsiae 100 Part, 100 parts of balloonflower root, 200 parts of coix seed, 200 parts of oriental wormwood, 180 parts of RADIX POLYGONI MULTIFLORI PREPARATA, 120 parts of the radix paeoniae rubrathe, 150 parts of the root of herbaceous peony, 150 parts of the dried rhizome of rehmannia, 200 parts of honeysuckle, 200 parts of dandelion, 200 parts of Chinese violet, 120 parts of the capsule of weeping forsythia, 100 parts of the coptis, 120 parts of chrysanthemum indicum, the Radix Astragali 150 Part, 150 parts of Radix Angelicae Sinensis, 60 parts of radix glycyrrhizae, 120 parts of Manyflower Gueldenstaedtid Herb, 60 parts of the wind-weed, 100 parts of scutellaria, 60 parts of lily, 100 parts of matrimony vine, Patrinia scaniosaefolia 120 parts of grass, 180 parts of the tuber of dwarf lilyturf, 150 parts of the stem pith of the rice-paper plant, 100 parts of radix scrophulariae, 100 parts of subprostrate sophora, 60 parts of fresh peppermint and the Chinese bulbul 150 Part.

As shown in figure 1, present invention also offers a kind of preparation method for the Chinese medicine preparation for treating whelk, including following step Suddenly：

In one preferred scheme, the preparation method of the Chinese medicine preparation of the treatment whelk, being additionally included in step 4 will be dry Extract powder, the first concentrate, the second concentrate and the mixing of the 3rd concentrate add polyethylene glycol and mixed, and it is blue or green that pill obtains the treatment The Chinese medicine preparation of spring acne；The preparation method of 3rd concentrate is as follows：

In one preferred scheme, the preparation method of the Chinese medicine preparation of the treatment whelk, pelletizing process described in step 4 It is as follows：

In such scheme, in order to preferably express pharmaceutical composition of the present invention, pharmaceutical composition of the invention can be made It is standby into clinically conventional formulation, such as：The formulations such as pill, granule, oral liquid, syrup, it is preferable that medicine of the invention Composition is prepared into granule, pill according to conventional fabrication process.

In one preferred scheme, the preparation method of the Chinese medicine preparation of the treatment whelk adds the weight of polyethylene glycol Part it is 5000-7000 parts, dry extract, the first concentrate, the mixture and polyethylene glycol of the second concentrate and the 3rd concentrate Mixed proportion be 1-2:5-8.

In one preferred scheme, the preparation method of the Chinese medicine preparation of the treatment whelk, spray drying parameters in step 1 For：Intake air temperature is 150-200 DEG C, and air outlet temperature is 60-90 DEG C.

Embodiment 1

A kind of Chinese medicine preparation for treating whelk, the main the following raw material included in parts by weight is made：

Red sage root 100g, Asian puccoon 180g, Exocarpium Citri Rubrum 80g, prepared RHIZOMA PINELLIZE without adju-vant 50g, Poria cocos 100g, hawthorn 120g, arisaema cum bile 30g, spina gleditsiae 80g, balloonflower root 50g, coix seed 180g, oriental wormwood 180g, RADIX POLYGONI MULTIFLORI PREPARATA 120g, radix paeoniae rubrathe 100g, root of herbaceous peony 100g, dried rhizome of rehmannia 100g, honeysuckle 180g, dandelion 180g, Chinese violet 180g, capsule of weeping forsythia 100g, coptis 80g, chrysanthemum indicum 100g, Radix Astragali 100g, Radix Angelicae Sinensis 100g with And radix glycyrrhizae 30g.

Embodiment 2

Red sage root 150g, Asian puccoon 210g, Exocarpium Citri Rubrum 100g, prepared RHIZOMA PINELLIZE without adju-vant 90g, Poria cocos 150g, hawthorn 150g, arisaema cum bile 60g, spina gleditsiae 100g, balloonflower root 100g, coix seed 200g, oriental wormwood 200g, RADIX POLYGONI MULTIFLORI PREPARATA 180g, radix paeoniae rubrathe 120g, root of herbaceous peony 150g, dried rhizome of rehmannia 150g, gold and silver Flower 200g, dandelion 200g, Chinese violet 200g, capsule of weeping forsythia 120g, coptis 100g, chrysanthemum indicum 120g, Radix Astragali 150g, Radix Angelicae Sinensis 150g And radix glycyrrhizae 60g.

Embodiment 3

Red sage root 200g, Asian puccoon 250g, Exocarpium Citri Rubrum 120g, prepared RHIZOMA PINELLIZE without adju-vant 120g, Poria cocos 200g, hawthorn 180g, arisaema cum bile 90g, soap Pierce 120g, balloonflower root 150g, coix seed 250g, oriental wormwood 250g, RADIX POLYGONI MULTIFLORI PREPARATA 220g, radix paeoniae rubrathe 150g, root of herbaceous peony 200g, dried rhizome of rehmannia 200g, gold Honeysuckle flower 250g, dandelion 250g, Chinese violet 250g, capsule of weeping forsythia 160g, coptis 120g, chrysanthemum indicum 160g, Radix Astragali 200g, Radix Angelicae Sinensis 200g and radix glycyrrhizae 90g.

Embodiment 4

Red sage root 100g, Asian puccoon 180g, Exocarpium Citri Rubrum 80g, prepared RHIZOMA PINELLIZE without adju-vant 50g, Poria cocos 100g, hawthorn 120g, arisaema cum bile 30g, spina gleditsiae 80g, balloonflower root 50g, coix seed 180g, oriental wormwood 180g, RADIX POLYGONI MULTIFLORI PREPARATA 120g, radix paeoniae rubrathe 100g, root of herbaceous peony 100g, dried rhizome of rehmannia 100g, honeysuckle It is 180g, dandelion 180g, Chinese violet 180g, capsule of weeping forsythia 100g, coptis 80g, chrysanthemum indicum 100g, Radix Astragali 100g, Radix Angelicae Sinensis 100g, sweet Careless 30g, Manyflower Gueldenstaedtid Herb 100g, wind-weed 30g, scutellaria 80g, lily 30g, matrimony vine 50g, field pennycress 100g, tuber of dwarf lilyturf 120g, the stem pith of the rice-paper plant 120g, radix scrophulariae 50g, subprostrate sophora 80g, fresh peppermint 30g and Chinese bulbul 100g.

Embodiment 5

Red sage root 150g, Asian puccoon 210g, Exocarpium Citri Rubrum 100g, prepared RHIZOMA PINELLIZE without adju-vant 90g, Poria cocos 150g, hawthorn 150g, arisaema cum bile 60g, spina gleditsiae 100g, balloonflower root 100g, coix seed 200g, oriental wormwood 200g, RADIX POLYGONI MULTIFLORI PREPARATA 180g, radix paeoniae rubrathe 120g, root of herbaceous peony 150g, dried rhizome of rehmannia 150g, gold and silver Flower 200g, dandelion 200g, Chinese violet 200g, capsule of weeping forsythia 120g, coptis 100g, chrysanthemum indicum 120g, Radix Astragali 150g, Radix Angelicae Sinensis 150g, radix glycyrrhizae 60g, Manyflower Gueldenstaedtid Herb 120g, wind-weed 60g, scutellaria 100g, lily 60g, matrimony vine 100g, field pennycress 120g, the tuber of dwarf lilyturf 180g, stem pith of the rice-paper plant 150g, radix scrophulariae 100g, subprostrate sophora 100g, fresh peppermint 60g and Chinese bulbul 150g.

Embodiment 6

Red sage root 200g, Asian puccoon 250g, Exocarpium Citri Rubrum 120g, prepared RHIZOMA PINELLIZE without adju-vant 120g, Poria cocos 200g, hawthorn 180g, arisaema cum bile 90g, soap Pierce 120g, balloonflower root 150g, coix seed 250g, oriental wormwood 250g, RADIX POLYGONI MULTIFLORI PREPARATA 220g, radix paeoniae rubrathe 150g, root of herbaceous peony 200g, dried rhizome of rehmannia 200g, gold Honeysuckle flower 250g, dandelion 250g, Chinese violet 250g, capsule of weeping forsythia 160g, coptis 120g, chrysanthemum indicum 160g, Radix Astragali 200g, Radix Angelicae Sinensis 200g, radix glycyrrhizae 90g, Manyflower Gueldenstaedtid Herb 160g, wind-weed 90g, scutellaria 120g, lily 90g, matrimony vine 150g, field pennycress 160g, the tuber of dwarf lilyturf 220g, stem pith of the rice-paper plant 180g, radix scrophulariae 150g, subprostrate sophora 120g, fresh peppermint 90g and Chinese bulbul 200g.

Embodiment 7

On the basis of the formula of embodiment 2, a kind of preparation method for the Chinese medicine preparation for treating whelk, including following step Suddenly：

Step 1, the red sage root decocted 2 times, adds 8 times of water for the first time, the water for adding 6 times second decocts 1.5 every time, Merge decoction twice and cross 100 eye mesh screens, concentrate, add isometric mass concentration and stir 20min for 70% ethanol, stand, Ethanol is reclaimed, is concentrated, concentrate is spray-dried again obtains dry extract, standby.

Step 2, Asian puccoon, Exocarpium Citri Rubrum, prepared RHIZOMA PINELLIZE without adju-vant, Poria cocos, hawthorn, arisaema cum bile, spina gleditsiae, balloonflower root, coix seed are weighed by weight And oriental wormwood, refluxing extraction 2 times, 6 times of water is added every time, and obtained extract solution is concentrated under reduced pressure, and adds isometric quality Concentration is 60% ethanol, is stood, and reclaims ethanol, is concentrated to give the first concentrate, standby.

Step 3, weigh by weight the tuber of multiflower knotweed, the radix paeoniae rubrathe, the root of herbaceous peony, radix rehmanniae recen, honeysuckle, dandelion, Chinese violet, the capsule of weeping forsythia, The coptis, chrysanthemum indicum, the Radix Astragali, Radix Angelicae Sinensis and radix glycyrrhizae, decoct twice, wherein the fleece-flower root, the root of herbaceous peony, the radix paeoniae rubrathe and radix rehmanniae recen smash grinding Into the water of coarse powder, for the first time 8 times of addition, temperature soaks 1h at 70 DEG C, decocts 0.5h, and the water of second of 6 times of addition decocts 1h, by two Secondary decoction merges filtering and flowed back to obtain the second concentrate, standby.

Embodiment 8

On the basis of the formula of embodiment 5, a kind of preparation method for the Chinese medicine preparation for treating whelk, including following step Suddenly：

Step 1, the red sage root decocted 2 times, adds 12 times of water for the first time, the water for adding 10 times second decocts 3h every time, Merge decoction twice and cross 100 eye mesh screens, concentrate, add isometric mass concentration and stir 40min for 80% ethanol, stand, Ethanol is reclaimed, is concentrated, concentrate is spray-dried again obtains dry extract, standby；Wherein, spray drying parameters are：Air inlet temperature Spend for 200 DEG C, air outlet temperature is 90 DEG C.

Step 2, Asian puccoon, Exocarpium Citri Rubrum, prepared RHIZOMA PINELLIZE without adju-vant, Poria cocos, hawthorn, arisaema cum bile, spina gleditsiae, balloonflower root, coix seed are weighed by weight And oriental wormwood, refluxing extraction 2 times, 10 times of water is added every time, and obtained extract solution is concentrated under reduced pressure, and adds isometric quality Concentration is 80% ethanol, is stood, and reclaims ethanol, is concentrated to give the first concentrate, standby.

Step 3, weigh by weight the tuber of multiflower knotweed, the radix paeoniae rubrathe, the root of herbaceous peony, radix rehmanniae recen, honeysuckle, dandelion, Chinese violet, the capsule of weeping forsythia, The coptis, chrysanthemum indicum, the Radix Astragali, Radix Angelicae Sinensis and radix glycyrrhizae, decoct twice, wherein the fleece-flower root, the root of herbaceous peony, the radix paeoniae rubrathe and radix rehmanniae recen smash grinding Into the water of coarse powder, for the first time 12 times of addition, temperature soaks 3h at 90 DEG C, decocts 1.5h, and the water of second of 10 times of addition decocts 3h, by Decoction merges filtering and flowed back to obtain the second concentrate twice, standby.

It is additionally included in step 4 to mix to add by dry extract, the first concentrate, the second concentrate and the 3rd concentrate and gathers Ethylene glycol is mixed, and pill obtains the Chinese medicine preparation of the treatment whelk；The preparation method of 3rd concentrate is as follows：

Manyflower Gueldenstaedtid Herb, the wind-weed, scutellaria, lily, matrimony vine, field pennycress, the tuber of dwarf lilyturf, the stem pith of the rice-paper plant, radix scrophulariae, mountain beans are weighed by weight Root, fresh peppermint and the Chinese bulbul, are decocted 2 times, and 12 times of water is added for the first time, and the water of second of 10 times of addition decocts 3h every time, Merge medical filtration twice, concentration adds isometric mass concentration and stirs 40min for 90% ethanol, stand, reclaims ethanol, It is concentrated to give the 3rd concentrate.

Wherein, the Chinese medicine preparation of described treatment whelk, pelletizing process is as follows described in step 4：

Dry extract, the first concentrate, the second concentrate and the 3rd concentrate are mixed and add polyethylene glycol mixing, insulation At 100 DEG C, -8 DEG C of liquid paraffin is instilled, liquid paraffin is removed, selects ball, the Chinese medicine preparation of the treatment whelk is produced.

Wherein, the Chinese medicine preparation of described treatment whelk, the parts by weight for adding polyethylene glycol are 7000 parts, dry extract Powder, the first concentrate, the second concentrate and the mixture of the 3rd concentrate and the mixed proportion of polyethylene glycol are 1:4.

Embodiment 9

Step 1, take the red sage root to add water to cook 2 times, for the first time 10 times of amounts, decoct 2 hours, second of 8 times of amount, decocting time 2 hours；Merging filtrate simultaneously crosses 100 eye mesh screens, is concentrated into relative density 1.15 (60 DEG C), adds isometric mass concentration Stirred 30 minutes for 75% ethanol, stand 12 hours in the case where temperature is 60 DEG C, take supernatant to reclaim ethanol, be concentrated into 1.10 (60 DEG C), concentrate obtains dry extract in spray drying (178 DEG C of EAT, 75 DEG C of leaving air temp), standby.

Step 2, take Asian puccoon, Exocarpium Citri Rubrum, prepared RHIZOMA PINELLIZE without adju-vant, Poria cocos, hawthorn, arisaema cum bile, spina gleditsiae, balloonflower root, coix seed, oriental wormwood totally 10 taste Extract solution is transferred to backflow concentration by the prepared slices of Chinese crude drugs, the water of heating and refluxing extraction 2 times in multi-function extractor, every time 8 times of amounts Carry out being concentrated under reduced pressure into relative density in tank for 1.15 (60 DEG C), it is 70% ethanol to add isometric concentration.Temperature for (2 DEG C- 10 DEG C) in deposit standing 48 hours, take supernatant by decoction be transferred to recovery reclaim ethanol tower in reclaim ethanol, be concentrated into relatively close Spend for 1.20 (60 DEG C) the first concentrate, it is standby.

Step 3, take RADIX POLYGONI MULTIFLORI PREPARATA, the radix paeoniae rubrathe, the root of herbaceous peony, radix rehmanniae recen, honeysuckle, dandelion, Chinese violet, the capsule of weeping forsythia, the coptis, mother chrysanthemum Flower, the Radix Astragali, Radix Angelicae Sinensis, radix glycyrrhizae amount to 13 kinds of prepared slices of Chinese crude drugs；Wherein the fleece-flower root, the root of herbaceous peony, the radix paeoniae rubrathe, radix rehmanniae recen carry out coarse powder, afterwards will The water of 10 times of amounts is added in prepared slices of Chinese crude drugs input multi-function extractor for the first time, temperature is soaked 2 hours in 80 DEG C of temperature, starts decoction 1 Hour, released liquor, add water 8 times of water measured for the second time, decocts 2 hours, the decoction decocted afterwards with first time merges filtering one Rise backflow be concentrated into 1.20 (DEG C) the second concentrate, it is standby.

Step 4, dry extract, the first concentrate, the second concentrate, three of the above drug extract add polyethylene glycol 6000, ratio is 1:5, it is well mixed, moves into pill dripping machine, at 80 DEG C of insulation, instills -5 DEG C of liquid paraffin, remove liquid stone Wax, selects ball, produces the Chinese medicine preparation of the treatment whelk.Wherein, the preparation method more than, those skilled in the art Appropriate auxiliary material is added in the preparation method technology granule or tablet are may be made as with conventional formulation method, it is same to obtain institute State the Chinese medicine preparation for the treatment of whelk.

Comparative example：

In order to illustrate the present invention treatment whelk Chinese medicine preparation beneficial effect, the present invention have chosen hospital clinic and Clinic case has carried out clinical test, 100 whelk patients is randomly divided into 2 groups, respectively treatment group and control group, this 10 years old, oldest 45 years old of 100 patient age minimums；The course of disease most short 3 months, most long 3 years；Treatment group：Man 30 Example, female 20；Control group：Man 23, female 27.Two groups of patients compare no statistics in terms of sex, age, course of disease length Meaning, with comparativity；Concrete outcome is as follows：

Treatment group：The Chinese medicine preparation prepared using embodiment 9, takes morning and evening sub-service after l agent, decocting daily.During treatment Avoid pungent food greasy or greasy and surfeit flavour food, many food fresh vegetables fruit, keeps happy.Disabling excitant cosmetics, Other paste of external application or medicine can be washed one's face to prevent clogging of pores with warm water, and sulfur soap may also be used for washing one's face, and be avoided with washing one's face Milk；To prevent inflammation from spreading, acne should not be extruded.

Control group：3 times a day by oral vitamin C, each 0.3g；Administration of roxithromycin piece, 3 times a day, each 65mg, mouth Take vitamin B6.Simultaneously outside apply " Metrogel ", during treatment taboo and care method ibid.

Wherein treatment group 2 days is 1 course for the treatment of to treat；Control group 5 days is 1 course for the treatment of to treat.

Differentiation of symptoms and signs for classification of syndrome：1. lung meridian wind-heat type：The aobvious red of papule, or itch or pain, yellow tongue fur tongue is red, superficial and rapid pulse；2. phlegm wet condenses Type：Site of pathological change is in tumour shape, and loose stool, the thin tongue of tongue are fat, slippery；3. damp-heat accumulation type：Fash is red and swollen or even has warts, pain, Yellow urine constipation, yellow and greasy fur tongue is red, slippery and rapid pulse.

Disease severity is classified：Slightly (I grades)：Total skin damaged quantity is less than 30, based on acne and have a small amount of papule or Person's warts；Moderate (II grades)：Total skin damaged quantity 30450, has acne and has the papule or warts of moderate quatity；Moderate (III Level)：Total skin damaged quantity 51-100, big inflammatory skin damaged is accidental, a large amount of papules or warts, and tubercle number is less than 3；Severe (IV grade)：Total skin damaged quantity is more than 100, Cystic acne nodosum, with pain, tumour tubercle or more than 3.

The standard of curative effect evaluation reference《TCM syndrome diagnosis and treatment standard》Efficacy assessment standard：

Cure：The symptoms such as fash disappear, and skin recovers normal condition；

Take a turn for the better：Symptom disappearance half such as fash or so；

It is not cured：The symptoms such as fash do not change substantially.

Total effective rate is in terms of controlling and take a turn for the better further.

Shown according to clinical effectiveness, all types of patient's Mean treatment durations for the treatment of group will be less than control group, treatment group each Type patient's total effective rate is higher than control group, between the two statistically significant (the P of comparing difference<0.05), specific treatment knot Fruit is shown in Table 1, and Chinese medicine preparation of the present invention cures total effective rate and reached 84% as shown in Table 1, and the total effective rate of control group Just 50%, so the pharmaceutical composition of the present invention is the active drug for treating whelk, and with good clinical meaning, significantly Economic and social benefit.Pharmaceutical composition of the present invention is natural traditional Chinese medicine preparation, is had no adverse reaction and toxic side effect, and the present invention Pharmaceutical composition effect is comprehensive, and clinical drug is better, significantly improves the compliance and quality of life of patient, has Significant clinical generalization value.

1 two groups of distinct methods treatment Comparison of therapeutic of table

Specific case：

Lee, 18 years old, female had 2 years medical histories, cheek and the multiple acne of forehead, especially before and after menstruation, and acne are aggravated, and applied Smear and take other drugs and have no significant results, the Chinese medicine preparation prepared using embodiments of the invention 9 takes l agent, water daily Morning and evening sub-service after decocting, 6 days/week, continuously takes one month, avoid pungent food greasy or greasy and surfeit flavour food during treatment, many foods Fresh vegetables fruit, keeps happy.Excitant cosmetics, other paste of external application or medicine are disabled to prevent clogging of pores, It can be washed one's face with warm water, sulfur soap may also be used for washing one's face, and avoids and uses mildy wash；To prevent inflammation from spreading, acne should not be extruded.Medication Period has no adverse reaction, and face acne disappears, no recurrence, follow-up 1 year, patient body health, no sequel.

Piao certain, 35 years old, man, have 1 year medical history, face nose and the multiple acne of thoracic dorsal, with face be many hair bands, use the present invention Chinese medicine preparation prepared by embodiment 8, morning and evening sub-service after decocting 6 days/week, is continuously taken two weeks, avoid pungent food oil during treatment Greasy or greasy and surfeit flavour food, many food fresh vegetables fruit, keeps happy.Disable excitant cosmetics, external application other cream Agent or medicine can be washed one's face to prevent clogging of pores with warm water, and sulfur soap may also be used for washing one's face, and avoids and uses mildy wash；To prevent inflammation Disease is spread, and should not extrude acne.Had no adverse reaction during medication, face acnes disappear, no recurrence, follow-up 1 year, patient body is good for Health, no sequel.

In summary, pharmaceutical composition of the present invention is natural traditional Chinese medicine preparation, is had no adverse reaction and toxic side effect, and the present invention Pharmaceutical composition effect is comprehensive, and clinical drug is better, significantly improves the compliance and quality of life of patient, has Significant clinical generalization value.

Although embodiment of the present invention is disclosed as above, it is not restricted in specification and embodiment listed With it can be applied to various suitable the field of the invention completely, can be easily for those skilled in the art Other modification is realized, therefore under the universal limited without departing substantially from claim and equivalency range, the present invention is not limited In specific details and shown here as the legend with description.

Claims

1. a kind of Chinese medicine preparation for treating whelk, wherein, the main raw material included in parts by weight：

100-200 parts of the red sage root, 180-250 parts of Asian puccoon, 80-120 parts of Exocarpium Citri Rubrum, 50-120 parts of prepared RHIZOMA PINELLIZE without adju-vant, 100-200 parts of Poria cocos, mountain 120-180 parts of short, bristly hair or beard, 30-90 parts of arisaema cum bile, 80-120 parts of spina gleditsiae, 50-150 parts of balloonflower root, 180-250 parts of coix seed, oriental wormwood 180- 250 parts, 120-220 parts of RADIX POLYGONI MULTIFLORI PREPARATA, 100-150 parts of the radix paeoniae rubrathe, 100-200 parts of the root of herbaceous peony, 100-200 parts of the dried rhizome of rehmannia, honeysuckle 180-250 Part, 180-250 parts of dandelion, 180-250 parts of Chinese violet, 100-160 parts of the capsule of weeping forsythia, 80-120 parts of the coptis, chrysanthemum indicum 100-160 Part, 100-200 parts of the Radix Astragali, 100-200 parts of Radix Angelicae Sinensis and 30-90 parts of radix glycyrrhizae.

2. the Chinese medicine preparation of whelk is treated as claimed in claim 1, wherein, in addition to the following raw material in parts by weight：

100-160 parts of Manyflower Gueldenstaedtid Herb, 30-90 parts of the wind-weed, 80-120 parts of scutellaria, 30-90 parts of lily, 50-150 parts of matrimony vine, field pennycress 100-160 parts, 120-220 parts of the tuber of dwarf lilyturf, 120-180 parts of the stem pith of the rice-paper plant, 50-150 parts of radix scrophulariae, 80-120 parts of subprostrate sophora, fresh peppermint 30- 90 parts and 100-200 parts of the Chinese bulbul.

3. the Chinese medicine preparation of whelk is treated as claimed in claim 2, wherein, including the following raw material in parts by weight：

150 parts of the red sage root, 210 parts of Asian puccoon, 100 parts of Exocarpium Citri Rubrum, 90 parts of prepared RHIZOMA PINELLIZE without adju-vant, 150 parts of Poria cocos, 150 parts of hawthorn, 60 parts of arisaema cum bile, 100 parts of spina gleditsiae, 100 parts of balloonflower root, 200 parts of coix seed, 200 parts of oriental wormwood, 180 parts of RADIX POLYGONI MULTIFLORI PREPARATA, 120 parts of the radix paeoniae rubrathe, 150 parts of the root of herbaceous peony, life 150 parts of ground, 200 parts of honeysuckle, 200 parts of dandelion, 200 parts of Chinese violet, 120 parts of the capsule of weeping forsythia, 100 parts of the coptis, chrysanthemum indicum 120 Part, 150 parts of the Radix Astragali, 150 parts of Radix Angelicae Sinensis, 60 parts of radix glycyrrhizae, 120 parts of Manyflower Gueldenstaedtid Herb, 60 parts of the wind-weed, 100 parts of scutellaria, 60 parts of lily, matrimony vine 100 parts, 120 parts of field pennycress, 180 parts of the tuber of dwarf lilyturf, 150 parts of the stem pith of the rice-paper plant, 100 parts of radix scrophulariae, 100 parts of subprostrate sophora, 60 parts of fresh peppermint and 150 parts of the Chinese bulbul.

4. a kind of preparation method of the Chinese medicine preparation for the treatment of whelk as claimed in claim 1 or 2, wherein, including following step Suddenly：

Step 1, the red sage root decocted 2 times, add 8-12 times of water for the first time, the water for adding 6-10 times second, each decoction 1.5-3h, merges decoction twice and crosses 100 eye mesh screens, concentrate, add isometric mass concentration and stirred for 70-80% ethanol 20-40min, stands, and reclaims ethanol, concentrates, concentrate is spray-dried again obtains dry extract, standby；

Step 2, weigh by weight Asian puccoon, Exocarpium Citri Rubrum, prepared RHIZOMA PINELLIZE without adju-vant, Poria cocos, hawthorn, arisaema cum bile, spina gleditsiae, balloonflower root, coix seed and Oriental wormwood, the water of refluxing extraction 2 times, every time 6-10 times of addition, obtained extract solution is concentrated under reduced pressure, and adds isometric quality dense Spend for 60-80% ethanol, stand, reclaim ethanol, be concentrated to give the first concentrate, it is standby；

Step 3, weigh by weight the tuber of multiflower knotweed, the radix paeoniae rubrathe, the root of herbaceous peony, radix rehmanniae recen, honeysuckle, dandelion, Chinese violet, the capsule of weeping forsythia, the coptis, Chrysanthemum indicum, the Radix Astragali, Radix Angelicae Sinensis and radix glycyrrhizae, decoct twice, and wherein the fleece-flower root, the root of herbaceous peony, the radix paeoniae rubrathe and radix rehmanniae recen, which are smashed, grinds to form slightly Powder, first time adds temperature leaching 1-3h at 8-12 times of water, 70-90 DEG C, decocts 0.5-1.5h, and 6-10 times of water is added for the second time, 1-3h is decocted, decoction will merge filtering twice and flow back to obtain the second concentrate, it is standby；

Step 4, dry extract, the first concentrate and the second concentrate mixed add polyethylene glycol and mix, pill obtains described control Treat the Chinese medicine preparation of whelk.

5. the Chinese medicine preparation for the treatment of whelk as claimed in claim 4, wherein, it is additionally included in dry extract, the in step 4 One concentrate, the second concentrate and the mixing of the 3rd concentrate add polyethylene glycol and mixed, and pill is obtained in the treatment whelk Medicine preparation；The preparation method of 3rd concentrate is as follows：

Weigh Manyflower Gueldenstaedtid Herb by weight, it is the wind-weed, scutellaria, lily, matrimony vine, field pennycress, the tuber of dwarf lilyturf, the stem pith of the rice-paper plant, radix scrophulariae, subprostrate sophora, fresh Peppermint and the Chinese bulbul, are decocted 2 times, and 8-12 times of water is added for the first time, and the water of second of 6-10 times of addition decocts 1.5- every time 3h, merges medical filtration twice, and concentration adds isometric mass concentration and stirs 20-40min for 80-90% ethanol, stands, Ethanol is reclaimed, the 3rd concentrate is concentrated to give.

6. the Chinese medicine preparation of whelk is treated as claimed in claim 4, wherein, pelletizing process is as follows described in step 4：

Dry extract, the first concentrate, the second concentrate and the 3rd concentrate are mixed and add polyethylene glycol mixing, 60- is incubated At 100 DEG C, the liquid paraffin of -3--8 DEG C of instillation removes liquid paraffin, selects ball, produces the Chinese medicine preparation of the treatment whelk.

7. the Chinese medicine preparation of whelk is treated as claimed in claim 6, wherein, the parts by weight for adding polyethylene glycol are 5000- 7000 parts, dry extract, the first concentrate, the mixture and the mixed proportion of polyethylene glycol of the second concentrate and the 3rd concentrate For 1-2:5-8.

8. the Chinese medicine preparation of whelk is treated as claimed in claim 4, wherein, spray drying parameters are in step 1：Air inlet Temperature is 150-200 DEG C, and air outlet temperature is 60-90 DEG C.