CN103372178B - Medicament and preparation method thereof - Google Patents
Medicament and preparation method thereof Download PDFInfo
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- CN103372178B CN103372178B CN201210106927.4A CN201210106927A CN103372178B CN 103372178 B CN103372178 B CN 103372178B CN 201210106927 A CN201210106927 A CN 201210106927A CN 103372178 B CN103372178 B CN 103372178B
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Abstract
The invention relates to the field of health products, and discloses a medicament. The medicament comprises main components of natural precious herbs such as morinda officinalis, herba cistanche, gastrodia elata, eucommia ulmoides, polygonum multiflorum, saffron crocus, medlar, angelica sinensis, rhizoma polygonati, pseudo-ginseng, lucid ganoderma, ginseng and the like. The invention also discloses the content of each component. The medicament comprises a plurality of effective ingredients of panaxoside, panaxadiol saponin and the like, has the functions of improving blood microcirculation, relieving and balancing cranial nerve, smoothing lymph to expel toxin, and promoting metabolism, contains starch, protein, fat, tannin, flavonoids compounds, phenolic compound and trace volatile oil, and also contains microelements iron, zinc and the like with biological activity; the leaf and stem contain a little of alkaloid, which has the functions of whitening the skin, resisting fatigue and caducity, improving mental sleep, physical power and function, and the like. The invention also discloses a preparation method of the medicament disclosed by the invention. The method comprises the steps of selecting materials, cleaning, fertilizing, drying and mechanically crushing. The process is advanced and unique; the dosage form can be changed; any other chemical reagent is not added; the medicament is environment-friendly.
Description
Technical field
The present invention and health preserving product scope, disclose a kind of medicine and preparation method thereof.
Background technology
Along with socioeconomic development, people's consumption idea is also changing step by step, and people are also higher to the expected value of daily life, and this is mainly reflected in the develop rapidly of health preserving product etc. industry.
Before 5000, ancient Chinese have just found herbal health preserving effect, initial 3000, it is for maintaining healthy rather than treatment disease that people take herbal object mostly, people's health status can be improved and promote to the edible correct herbaceous plant combining of accumulating over a long period, and autoimmunity resistance is improved greatly.The health of foot can systemic health.Clinical medicine is found, fatty liver, diabetes, gynaecopathia, hypertension, cerebral thrombosis, heart disease, prostatosis, gout, insomnia, arthritis, hyperosteogeny diseases all can be cold and cool from foot the earliest, and numbness, aches, swelling, knots, and the discomforts such as pain reflect, long-run development local disease will develop into chronic whole body severe disease, shows that 40%～50% disease is that microcirculation is obstructed through investigation, and 60～70% subhealth states are that organismic internal environment endotoxin is accumulated and caused.From collaterals of human, learn, the vital organs of the human body have corresponding echo area on foot, foot is not only the starting point of Three Yin Channels of Foot, or the termination of the three yang channels of foots, hallux toe is communicated with liver spleen channel, and the 4th apotelus leads to gallbladder meridian, little toe ownership urinary bladder channel, kidney channel place vola portion, therefore, foot bath service is the large industry of one in health preserving.
Current existing health preserving product category is various, but the following shortcoming of tool: (1) effect is single, and most health preserving product just has a certain specially good effect pointedly; (2) orally use, archaism cloud " being three minutes poison of medicine ", oral medication can cause the harmful components in medicine to be detained, to accumulate, thereby causes the injury to the vitals such as liver, kidney in human body.
Therefore, invent a kind of many effects and health preserving product that can external and there is important practical value.
Summary of the invention
The present invention's the first object has been to provide a kind of medicine, and its main component is as follows: Radix Morindae Officinalis (wine is processed) 1.2～1.5%, Herba Cistanches (wine is processed) 0.5～1.5%, Cornu Cervi Pantotrichum (unhairing) 0.1～0.5%, Fructus Lycii 1.0～1.6%, Flos Albiziae 1.0～3.5%, Lignum Santali Albi 0.1～0.5%, Herba Artemisiae Scopariae 0.1～0.5%, RHIZONA GASTRODIAE 1.2～1.8%, Cortex Eucommiae(processed with salt) 1.0～1.2%, Folium Ginkgo 0.1～0.5%, the Radix Astragali 1.0～1.2%, Lignum Aquilariae Resinatum 0.1～0.5%, Folium Artemisiae Argyi 1.2～4.5%, Pericarpium Citri Reticulatae 0.1～0.2%, Fructus Crataegi 0.1～0.2%, Fructus Schisandrae Chinensis 1.2～3.5% Radix Et Rhizoma Rhei 1.0～2.5%, Radix Paeoniae Rubra 1.2～2.3%, Olibanum (wine is processed) 1.5～2.5%, Myrrha (processed with vinegar) 0.5～2.5%, Radix Angelicae Sinensis 1.0～1.2%, cooked Radix Notoginseng 1.0～1.5%, Stigma Croci 0.1～0.5%, lavandula angustifolia 1.5～2.3%, Semen Persicae 0.1～0.5%, Radix Polygalae 1.2～1.5%, Ganoderma sinense Zhao Xu et Zhang 0.1～0.5%, Radix Rhodiolae 0.1～0.5%, Radix Polygoni Multiflori (wine is processed) 1.0～2.5%, Rhizoma Polygonati (wine is processed) 0.1～0.5%, Radix Sophorae Flavescentis 0.1～0.5%, Fructus Cnidii 0.1～0.5%, Rhizoma Smilacis Glabrae 0.1～0.5%, Radix Aconiti Lateralis Preparata 0.5～1.5%, Borneolum Syntheticum 1.0～1.5%, Rhizoma Polygonati Odorati 0.1～0.5%, Flos Carthami 1.5～2.5%, Ramulus Mori 1.0～1.5%, Sanguis Draxonis 0.1～0.2%, Radix Angelicae Pubescentis 1.0～1.5%, Rhizoma Chuanxiong 1.0～1.5%, Ramulus Cinnamomi 0.1～0.5%, Fructus Gardeniae Preparatus 1.0～3.5%, Radix Scutellariae 1.5～2.5%, Cortex Phellodendri 1.5～3.5%, Herba Lycopodii 1.6～2.5%, the Radix Angelicae Dahuricae 1.8～2.5%, Poria 1.0～1.5%, Margarita 1.5～2.5%, Herba speranskiae tuberculatae 1.5～2.5%, Rhizoma Zingiberis 1.5～3.5%, Bulbus Lilii 0.1～0.5%, Semen Ziziphi Spinosae 1.2～2.5%, Radix Salviae Miltiorrhizae 1.2～2.5%, Radix Ginseng 0.1～0.2% and Magnetitum 0.5～1.5%.
Radix Morindae Officinalis in this medicine (wine is processed), Herba Cistanches (wine is processed), Olibanum (wine is processed), Radix Polygoni Multiflori (wine is processed), Rhizoma Polygonati (wine is processed) dry gained Radix Morindae Officinalis, Herba Cistanches, Olibanum, Radix Polygoni Multiflori and Rhizoma Polygonati spice after referring to Radix Morindae Officinalis, Herba Cistanches, Olibanum, Radix Polygoni Multiflori and the Rhizoma Polygonati of selecting materials after cleaning being stirred with wine respectively; Myrrha (processed with vinegar) dries gained Myrrha after referring to and stirring with vinegar; Cornu Cervi Pantotrichum (unhairing) refers to the Cornu Cervi Pantotrichum of removing hair.
In the composition of this medicine, contain ginsenoside, ginseng diol saponin, Effects of Ginseng Root Saponins, ginsenoside Rb1, baicalin, matrine, globulariacitrin, chlorogenic acid, Radix Notoginseng total arasaponins, total flavones, ligustrazine, Inokopolyose, Dihuang polysaccharide, pachyman, the multiple beneficial materials such as gutta-percha, its effect is as follows: ginsenoside has protective action to radiation-induced cell membrane damage; Ginseng diol saponin has protective effect to myocardial ischemia-reperfusion dog cardiac function; Effects of Ginseng Root Saponins has obvious anti-DNA damnification and antimutagenic effect; Ginsenoside Rb1 lowly has protective effect to irritability sexual behaviour; Radix Notoginseng total arasaponins significantly improves sarcoplasm nethike embrane calcium pump activity in myocardial cell, reduces myocardial cell Ca
2+, dog myocardial ischemia reperfusion injury is had to protective effect.In addition contain starch, protein, fat, tannin, flavone compound, phenolic compound and trace volatile oil, also contain and there are bioactive trace elements iron, aluminum, zinc, silver, cobalt, cadmium, titanium, molybdenum, manganese etc., in leaf and stem, contain a small amount of alkaloid.There is skin whitening, the functions such as the mental sleep of resisting fatigue, defying age and raising and physical function.
The corresponding gene of different effective ingredient in this medicine and the interaction of protein expression target spot, the content of raising catalase, superoxide dismutase activity and reduced glutathion, adenosine triphosphate.The 10 strain virus cytopathogenic effects relevant with respiratory tract infection are all had to inhibitory action in various degree, and the content by the somatostatin, vasoactive intestinal peptide etc. that affect the gastrin, motilin, Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 of excited gastrointestinal motility and suppress gastrointestinal motility in hypothalamus and gastrointestinal tract carrys out Gastrointestinal motility adjustment; There is good biologic activity, according to monarch, the minister of the number of expression and compound recipe, help, make theory and using dosage to be associated, totally improve curative effect.
This medicine has more unique hydrophilic infiltration composition, the Chinese medicine bioactive ingredients that gets rid of illness is transformed into micromolecule from macromole, effective ingredient is the through teleneuron of distributed by capillarity wall rapidly, by epidermal tissue's osmosis, activate meridians microcirculation, can powerful metabolism discharge the stagnant endotoxin of the stasis of blood in body, realize the identification of many target spots of Chinese medicine targeting, the original disease of health has corresponding sensation, everyone organismic internal environment is obstructed, body constitution is different, the toxin color of discharging is also different, and after foot bath, the color of water all can change, and opens the toxin expelling of real meaning.
Generally speaking, this medicine has the blood microcirculation of improvement, and unobstructed lympha toxin expelling, enhances metabolism, balance cranial nerve improves sleep, regulate foot and systemic blood circulation, activate trophocyte from top to bottom, intestine moistening toxin expelling relieves inflammation or internal heat, desalinate rapidly face's mottle, refinement wrinkle, expansible foot blood vessel microcirculation, for aspect effects such as the mental sleep of resisting fatigue, defying age and raising and physical functions.
Preferably, the main component of this medicine is as follows: Radix Morindae Officinalis (wine is processed) 1.5%, Herba Cistanches (wine is processed) 1.5%, Cornu Cervi Pantotrichum (unhairing) 0.5%, Fructus Lycii 1.6%, Flos Albiziae 3.5%, Lignum Santali Albi 0.5%, Herba Artemisiae Scopariae 0.5%, RHIZONA GASTRODIAE 1.8%, Cortex Eucommiae(processed with salt) 1.2%, Folium Ginkgo 0.5%, the Radix Astragali 1.2%, Lignum Aquilariae Resinatum 0.5%, Folium Artemisiae Argyi 4.5%, Pericarpium Citri Reticulatae 0.2%, Fructus Crataegi 0.2%, Fructus Schisandrae Chinensis 3.5%, Radix Et Rhizoma Rhei 2.5%, Radix Paeoniae Rubra 2.3%, Olibanum (wine is processed) 2.5%, Myrrha (processed with vinegar) 2.5%, Radix Angelicae Sinensis 1.2%, cooked Radix Notoginseng 1.5%, Stigma Croci 0.5%, lavandula angustifolia 2.3% Semen Persicae 0.5%, Radix Polygalae 1.5%, Ganoderma sinense Zhao Xu et Zhang 0.5%, Radix Rhodiolae 0.5%, Radix Polygoni Multiflori (wine is processed) 2.5%, Rhizoma Polygonati (wine is processed) 0.5%, Radix Sophorae Flavescentis 0.5%, Fructus Cnidii 0.5%, Rhizoma Smilacis Glabrae 0.5%, Radix Aconiti Lateralis Preparata 1.5%, Borneolum Syntheticum 1.5%, Rhizoma Polygonati Odorati 0.5%, Flos Carthami 2.5%, Ramulus Mori 1.5%, Sanguis Draxonis 0.2%, Radix Angelicae Pubescentis 1.5%, Rhizoma Chuanxiong 1.5%, Ramulus Cinnamomi 0.5%, Fructus Gardeniae Preparatus 3.5%, Radix Scutellariae 2.5%, Cortex Phellodendri 3.5%, Herba Lycopodii 2.5%, the Radix Angelicae Dahuricae 2.5%, Poria 1.5%, Margarita 2.5%, Herba speranskiae tuberculatae 2.5%, Rhizoma Zingiberis 3.5%, Bulbus Lilii 0.5%, Semen Ziziphi Spinosae 2.5%, Radix Salviae Miltiorrhizae 2.5%, Radix Ginseng 0.2% and Magnetitum 1.5%.
Radix Morindae Officinalis in this medicine (wine is processed), Herba Cistanches (wine is processed), Olibanum (wine is processed), Radix Polygoni Multiflori (wine is processed), Rhizoma Polygonati (wine is processed) dry gained Radix Morindae Officinalis, Herba Cistanches, Olibanum, Radix Polygoni Multiflori and Rhizoma Polygonati spice after referring to Radix Morindae Officinalis, Herba Cistanches, Olibanum, Radix Polygoni Multiflori and the Rhizoma Polygonati of selecting materials after cleaning being stirred with wine respectively; Myrrha (processed with vinegar) dries gained Myrrha after referring to and stirring with vinegar; Cornu Cervi Pantotrichum (unhairing) refers to the Cornu Cervi Pantotrichum of removing hair.
The second object of the present invention is the preparation method that discloses the above medicine, comprises the following steps:
(1) select raw material: choose the medical material of high-quality as raw material, select various medical materials to gather when active constituent content is the highest;
(2) clean: the medical material as raw material is cleaned, remove dirt, slag, it is thoroughly cleaned up;
(3) tentatively pulverize: the various medical materials after cleaning are mixed, through grinder, tentatively pulverize, preferred, preliminary pulverizing is the granule of 80～120 order sizes;
(4) fermentation: will pave through the preliminary medical material uniform particles of pulverizing, spray to infiltrate with wine and ferment, obtain fermented product, preferably spray and infiltrate with 50～60 degree grain wine, stir fermentation enzyme zymolysis in 7～15 days;
(5) cold drying: fermented product is carried out to oven drying at low temperature, obtain drying composite, preferred daylight dry in the sun 2～3 days, makes its bone dry;
(6) fine gtinding: drying composite is ground to and is equal to or greater than 200 object fine powders, obtain drug products.
The preparation method of medicine of the present invention is through selecting raw material, cleaning, fermentation, sun dehydration and mechanical activation comminution, and technique is advanced unique, and dosage form can change, and does not add any other chemical reagent, environmental protection.
Accompanying drawing explanation
Fig. 1 is the process flow diagram of preparation medicine of the present invention.
The specific embodiment
Below in conjunction with accompanying drawing and specific embodiment, describe the present invention in detail, in this illustrative examples of the present invention and explanation, be used for explaining the present invention, but not as a limitation of the invention.
Embodiment 1:
A medicine, its main component is as follows: Radix Morindae Officinalis (wine is processed) 1.2～1.5%, Herba Cistanches (wine is processed) 0.5～1.5%, Cornu Cervi Pantotrichum (unhairing) 0.1～0.5%, Fructus Lycii 1.0～1.6%, Flos Albiziae 1.0～3.5%, Lignum Santali Albi 0.1～0.5%, Herba Artemisiae Scopariae 0.1～0.5%, RHIZONA GASTRODIAE 1.2～1.8%, Cortex Eucommiae(processed with salt) 1.0～1.2%, Folium Ginkgo 0.1～0.5%, the Radix Astragali 1.0～1.2%, Lignum Aquilariae Resinatum 0.1～0.5%, Folium Artemisiae Argyi 1.2～4.5%, Pericarpium Citri Reticulatae 0.1～0.2%, Fructus Crataegi 0.1～0.2%, Fructus Schisandrae Chinensis 1.2～3.5% Radix Et Rhizoma Rhei 1.0～2.5%, Radix Paeoniae Rubra 1.2～2.3%, Olibanum (wine is processed) 1.5～2.5%, Myrrha (processed with vinegar) 0.5～2.5%, Radix Angelicae Sinensis 1.0～1.2%, cooked Radix Notoginseng 1.0～1.5%, Stigma Croci 0.1～0.5%, lavandula angustifolia 1.5～2.3%, Semen Persicae 0.1～0.5%, Radix Polygalae 1.2～1.5%, Ganoderma sinense Zhao Xu et Zhang 0.1～0.5%, Radix Rhodiolae 0.1～0.5%, Radix Polygoni Multiflori (wine is processed) 1.0～2.5%, Rhizoma Polygonati (wine is processed) 0.1～0.5%, Radix Sophorae Flavescentis 0.1～0.5%, Fructus Cnidii 0.1～0.5%, Rhizoma Smilacis Glabrae 0.1～0.5%, Radix Aconiti Lateralis Preparata 0.5～1.5%, Borneolum Syntheticum 1.0～1.5%, Rhizoma Polygonati Odorati 0.1～0.5%, Flos Carthami 1.5～2.5%, Ramulus Mori 1.0～1.5%, Sanguis Draxonis 0.1～0.2%, Radix Angelicae Pubescentis 1.0～1.5%, Rhizoma Chuanxiong 1.0～1.5%, Ramulus Cinnamomi 0.1～0.5%, Fructus Gardeniae Preparatus 1.0～3.5%, Radix Scutellariae 1.5～2.5%, Cortex Phellodendri 1.5～3.5%, Herba Lycopodii 1.6～2.5%, the Radix Angelicae Dahuricae 1.8～2.5%, Poria 1.0～1.5%, Margarita 1.5～2.5%, Herba speranskiae tuberculatae 1.5～2.5%, Rhizoma Zingiberis 1.5～3.5%, Bulbus Lilii 0.1～0.5%, Semen Ziziphi Spinosae 1.2～2.5%, Radix Salviae Miltiorrhizae 1.2～2.5%, Radix Ginseng 0.1～0.2% and Magnetitum 0.5～1.5%.
Radix Morindae Officinalis in this medicine (wine is processed), Herba Cistanches (wine is processed), Olibanum (wine is processed), Radix Polygoni Multiflori (wine is processed), Rhizoma Polygonati (wine is processed) dry gained Radix Morindae Officinalis, Herba Cistanches, Olibanum, Radix Polygoni Multiflori and Rhizoma Polygonati spice after referring to Radix Morindae Officinalis, Herba Cistanches, Olibanum, Radix Polygoni Multiflori and the Rhizoma Polygonati of selecting materials after cleaning being stirred with wine respectively; Myrrha (processed with vinegar) dries gained Myrrha after referring to and stirring with vinegar; Cornu Cervi Pantotrichum (unhairing) refers to the Cornu Cervi Pantotrichum of removing hair.
Embodiment 2:
A medicine, its main component is as follows: Radix Morindae Officinalis (wine is processed) 1.5%, Herba Cistanches (wine is processed) 1.5%, Cornu Cervi Pantotrichum (unhairing) 0.5%, Fructus Lycii 1.6%, Flos Albiziae 3.5%, Lignum Santali Albi 0.5%, Herba Artemisiae Scopariae 0.5%, RHIZONA GASTRODIAE 1.8%, Cortex Eucommiae(processed with salt) 1.2%, Folium Ginkgo 0.5%, the Radix Astragali 1.2%, Lignum Aquilariae Resinatum 0.5%, Folium Artemisiae Argyi 4.5%, Pericarpium Citri Reticulatae 0.2%, Fructus Crataegi 0.2%, Fructus Schisandrae Chinensis 3.5%, Radix Et Rhizoma Rhei 2.5%, Radix Paeoniae Rubra 2.3%, Olibanum (wine is processed) 2.5%, Myrrha (processed with vinegar) 2.5%, Radix Angelicae Sinensis 1.2%, cooked Radix Notoginseng 1.5%, Stigma Croci 0.5%, lavandula angustifolia 2.3% Semen Persicae 0.5%, Radix Polygalae 1.5%, Ganoderma sinense Zhao Xu et Zhang 0.5%, Radix Rhodiolae 0.5%, Radix Polygoni Multiflori (wine is processed) 2.5%, Rhizoma Polygonati (wine is processed) 0.5%, Radix Sophorae Flavescentis 0.5%, Fructus Cnidii 0.5%, Rhizoma Smilacis Glabrae 0.5%, Radix Aconiti Lateralis Preparata 1.5%, Borneolum Syntheticum 1.5%, Rhizoma Polygonati Odorati 0.5%, Flos Carthami 2.5%, Ramulus Mori 1.5%, Sanguis Draxonis 0.2%, Radix Angelicae Pubescentis 1.5%, Rhizoma Chuanxiong 1.5%, Ramulus Cinnamomi 0.5%, Fructus Gardeniae Preparatus 3.5%, Radix Scutellariae 2.5%, Cortex Phellodendri 3.5%, Herba Lycopodii 2.5%, the Radix Angelicae Dahuricae 2.5%, Poria 1.5%, Margarita 2.5%, Herba speranskiae tuberculatae 2.5%, Rhizoma Zingiberis 3.5%, Bulbus Lilii 0.5%, Semen Ziziphi Spinosae 2.5%, Radix Salviae Miltiorrhizae 2.5%, Radix Ginseng 0.2% and Magnetitum 1.5%.
Radix Morindae Officinalis in this medicine (wine is processed), Herba Cistanches (wine is processed), Olibanum (wine is processed), Radix Polygoni Multiflori (wine is processed), Rhizoma Polygonati (wine is processed) dry gained Radix Morindae Officinalis, Herba Cistanches, Olibanum, Radix Polygoni Multiflori and Rhizoma Polygonati spice after referring to Radix Morindae Officinalis, Herba Cistanches, Olibanum, Radix Polygoni Multiflori and the Rhizoma Polygonati of selecting materials after cleaning being stirred with wine respectively; Myrrha (processed with vinegar) dries gained Myrrha after referring to and stirring with vinegar; Cornu Cervi Pantotrichum (unhairing) refers to the Cornu Cervi Pantotrichum of removing hair.
Below for using the case of drug products of the present invention:
Case 1: certain female, 46 years old, insomnia, can only sleep 2～3 hours every night for a long time, and daytime, sleepy health was tired, used drug products of the present invention 15 days, and symptom is clearly better and can sleeps peacefully 5～6 hours, and sleep quality is splendid.Concrete using method is the warm water soaking biped 30-40 minute with this drug products and 40 ℃～45 ℃.
Case 2: certain female, 30 years old, face had speckle, and color is gloomy, and skin layer is coarse, and menoxenia is used drug products of the present invention about 28 days, and skin is obviously pale, delicacy.Concrete using method is the warm water soaking biped 30-40 minute with this drug products and 40 ℃～45 ℃.
Case 3: certain man, 36 years old, often to drink, the greasy seafood of happiness edible oil, suffers from gout, and after using drug products of the present invention, the elimination of swelling and ache is clearly better.Concrete using method is the warm water soaking biped 30-40 minute with this drug products and 40 ℃～45 ℃.
Case 4: certain female, 23 years old, usually weak, often brothers were cold and cool, and abdominal pain in menstruation is had rosy cheeks after using drug products of the present invention, and brothers turn temperature, and dysmenorrhea is eliminated.Concrete using method is the warm water soaking biped 30-40 minute with this drug products and 40 ℃～45 ℃.
Embodiment 3:
Fig. 1 is the preparation method of the medicine described in the embodiment of the present invention 1 and embodiment 2, and as can be seen from Figure 1, process for preparing medicine of the present invention is as follows:
The first step: select raw material, choose the required medical material of high-quality as raw material, select various medical materials to gather when active constituent content is the highest;
Second step: clean, the medical material as raw material is cleaned, remove dirt, slag, it is thoroughly cleaned up;
The 3rd step: tentatively pulverize, the various medical materials after cleaning are mixed, tentatively pulverize through grinder, preferred, preliminary pulverizing is the granule of 80～120 order sizes;
The 4th step: fermentation, will pave through the preliminary medical material uniform particles of pulverizing, with wine, spray to infiltrate and ferment, obtain fermented product, preferably with 50～60 degree grain wine, spray and infiltrate, stir fermentation enzyme zymolysis in 7～15 days;
The 5th step: cold drying, fermented product is carried out to oven drying at low temperature, obtain drying composite, preferred daylight dry in the sun 2～3 days, makes its bone dry;
The 6th step: fine gtinding, drying composite is ground to and is greater than or equal to 200 object fine powders, obtain drug products of the present invention.
Medicine of the present invention with and preparation method thereof there is following advantage:
1, in the composition of this medicine, contain ginsenoside, ginseng diol saponin, Effects of Ginseng Root Saponins, ginsenoside Rb1, baicalin, matrine, globulariacitrin, chlorogenic acid, Radix Notoginseng total arasaponins, total flavones, ligustrazine, Inokopolyose, Dihuang polysaccharide, pachyman, the multiple beneficial materials such as gutta-percha, its effect is as follows: ginsenoside has protective action to radiation-induced cell membrane damage; Ginseng diol saponin has protective effect to myocardial ischemia-reperfusion dog cardiac function; Effects of Ginseng Root Saponins has obvious anti-DNA damnification and antimutagenic effect; Ginsenoside Rb1 lowly has protective effect to irritability sexual behaviour; Radix Notoginseng total arasaponins significantly improves sarcoplasm nethike embrane calcium pump activity in myocardial cell, reduces myocardial cell Ca
2+, dog myocardial ischemia reperfusion injury is had to protective effect.In addition contain starch, protein, fat, tannin, flavone compound, phenolic compound and trace volatile oil, also contain and there are bioactive trace elements iron, aluminum, zinc, silver, cobalt, cadmium, titanium, molybdenum, manganese etc., in leaf and stem, contain a small amount of alkaloid.There are the aspect effects such as the mental sleep of resisting fatigue, defying age and raising and physical function.
2, the interaction of the corresponding gene of the different effective ingredient in this medicine and protein expression target spot, the content of raising catalase, superoxide dismutase activity and reduced glutathion, adenosine triphosphate.The 10 strain virus cytopathogenic effects relevant with respiratory tract infection are all had to inhibitory action in various degree, and the content by the somatostatin, vasoactive intestinal peptide etc. that affect the gastrin, motilin, Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 of excited gastrointestinal motility and suppress gastrointestinal motility in hypothalamus and gastrointestinal tract carrys out Gastrointestinal motility adjustment; There is good biologic activity.According to monarch, the minister of the number of expression and compound recipe, help, make theory and using dosage to be associated, totally improve curative effect.
3, this medicine has more unique hydrophilic infiltration composition, the Chinese medicine bioactive ingredients that gets rid of illness is transformed into micromolecule from macromole, effective ingredient is the through teleneuron of distributed by capillarity wall rapidly, by epidermal tissue's osmosis, activate meridians microcirculation, can powerful metabolism discharge the stagnant endotoxin of the stasis of blood in body, realize the identification of many target spots of Chinese medicine targeting, the original disease of health has corresponding sensation, everyone organismic internal environment is obstructed, body constitution is different, the toxin color of discharging is also different, and after foot bath, the color of water all can change, and opens the toxin expelling of real meaning.
4, the preparation method of medicine of the present invention is through selecting raw material, cleaning, fermentation, sun dehydration and mechanical activation comminution, and technique is simple, and does not add any other chemical reagent, environmental protection.
In sum, medicine of the present invention is compared with other foot bath product, the hydrophilic infiltration composition of tool uniqueness, the Chinese medicine bioactive ingredients that gets rid of illness is transformed into micromolecule from macromole, effective ingredient is the through teleneuron of distributed by capillarity wall rapidly, by epidermal tissue's osmosis, activate meridians microcirculation, can powerful metabolism discharge the stagnant endotoxin of the stasis of blood in body, realize the identification of many target spots of Chinese medicine targeting, the original disease of health has corresponding sensation, everyone organismic internal environment is obstructed, body constitution is different, the toxin color of discharging is also different, after foot bath, the color of water all can change, it is high-tech molecule foot bath element of new generation.This medicine can improve blood microcirculation, and unobstructed lympha toxin expelling, enhances metabolism, remove free radical, regulate foot and systemic blood circulation, activate trophocyte from top to bottom, the intestine moistening toxin expelling that relieves inflammation or internal heat, desalinates rapidly face's mottle, black eye, refinement wrinkle, pachylosis, the warm-heat effect of water, expansible foot blood vessel microcirculation, increase skin surface temperature, epiderm skin sweat gland has secretion, absorption and excretion, thermoregulation, breathing, thoughts and feelings waits effect, because itself just can absorb the drug, as by hot water, being more conducive to drug effect plays a role at human body, thereby strengthen foot and systemic blood circulation, healthy people is with the warm water soaking biped 30-40 minute of 40 ℃～45 ℃, it is 9～12 times that the flow of its systemic blood increases women, male be 12～15 times due to the increase of blood circulation amount, thereby regulate each endocrine function, impel each endocrine body of gland to secrete various hormones, as the thyroxin of thyroid secretion, the epinephrine of acth secretion, these hormones toxin expelling that all can enhance metabolism, after bathing, in water, make to see a large amount of interior metabolism products, as lactic acid crystallization, creatinine, uric acid etc. are discharged from, open the toxin expelling of real meaning, after bathing, whole body is light, spiritual happiness.
The technical scheme above embodiment of the present invention being provided is described in detail, applied specific case herein the principle of the embodiment of the present invention and embodiment are set forth, the explanation of above embodiment is only applicable to help to understand the principle of the embodiment of the present invention; , for one of ordinary skill in the art, according to the embodiment of the present invention, in the specific embodiment and range of application, all will change, in sum, this description should not be construed as limitation of the present invention meanwhile.
Claims (5)
1. a medicine, is characterized in that its main component is as follows: the Radix Morindae Officinalis 1.2～1.5% that wine is processed, the Herba Cistanches 0.5～1.5% that wine is processed, plucked Cornu Cervi Pantotrichum 0.1～0.5%, Fructus Lycii 1.0～1.6%, Flos Albiziae 1.0～3.5%, Lignum Santali Albi 0.1～0.5%, Herba Artemisiae Scopariae 0.1～0.5%, RHIZONA GASTRODIAE 1.2～1.8%, Cortex Eucommiae(processed with salt) 1.0～1.2%, Folium Ginkgo 0.1～0.5%, the Radix Astragali 1.0～1.2%, Lignum Aquilariae Resinatum 0.1～0.5%, Folium Artemisiae Argyi 1.2～4.5%, Pericarpium Citri Reticulatae 0.1～0.2%, Fructus Crataegi 0.1～0.2%, Fructus Schisandrae Chinensis 1.2～3.5%, Radix Et Rhizoma Rhei 1.0～2.5%, Radix Paeoniae Rubra 1.2～2.3%, the Olibanum 1.5～2.5% that wine is processed, the Myrrha 0.5～2.5% of processed with vinegar, Radix Angelicae Sinensis 1.0～1.2%, cooked Radix Notoginseng 1.0～1.5%, Stigma Croci 0.1～0.5%, lavandula angustifolia 1.5～2.3%, Semen Persicae 0.1～0.5%, Radix Polygalae 1.2～1.5%, Ganoderma sinense Zhao Xu et Zhang 0.1～0.5%, Radix Rhodiolae 0.1～0.5%, the Radix Polygoni Multiflori 1.0～2.5% that wine is processed, the Rhizoma Polygonati 0.1～0.5% that wine is processed, Radix Sophorae Flavescentis 0.1～0.5%, Fructus Cnidii 0.1～0.5%, Rhizoma Smilacis Glabrae 0.1～0.5%, Radix Aconiti Lateralis Preparata 0.5～1.5%, Borneolum Syntheticum 1.0～1.5%, Rhizoma Polygonati Odorati 0.1～0.5%, Flos Carthami 1.5～2.5%, Ramulus Mori 1.0～1.5%, Sanguis Draxonis 0.1～0.2%, Radix Angelicae Pubescentis 1.0～1.5%, Rhizoma Chuanxiong 1.0～1.5%, Ramulus Cinnamomi 0.1～0.5%, Fructus Gardeniae Preparatus 1.0～3.5%, Radix Scutellariae 1.5～2.5%, Cortex Phellodendri 1.5～3.5%, Herba Lycopodii 1.6～2.5%, the Radix Angelicae Dahuricae 1.8～2.5%, Poria 1.0～1.5%, Margarita 1.5～2.5%, Herba speranskiae tuberculatae 1.5～2.5%, Rhizoma Zingiberis 1.5～3.5%, Bulbus Lilii 0.1～0.5%, Semen Ziziphi Spinosae 1.2～2.5%, Radix Salviae Miltiorrhizae 1.2～2.5%, Radix Ginseng 0.1～0.2% and Magnetitum 0.5～1.5%.
2. medicine according to claim 1, is characterized in that its main component is as follows: the Radix Morindae Officinalis 1.5% that wine is processed, the Herba Cistanches 1.5% that wine is processed, plucked Cornu Cervi Pantotrichum 0.5%, Fructus Lycii 1.6%, Flos Albiziae 3.5%, Lignum Santali Albi 0.5%, Herba Artemisiae Scopariae 0.5%, RHIZONA GASTRODIAE 1.8%, Cortex Eucommiae(processed with salt) 1.2%, Folium Ginkgo 0.5%, the Radix Astragali 1.2%, Lignum Aquilariae Resinatum 0.5%, Folium Artemisiae Argyi 4.5%, Pericarpium Citri Reticulatae 0.2%, Fructus Crataegi 0.2%, Fructus Schisandrae Chinensis 3.5%, Radix Et Rhizoma Rhei 2.5%, Radix Paeoniae Rubra 2.3%, the Olibanum 2.5% that wine is processed, the Myrrha 2.5% of processed with vinegar, Radix Angelicae Sinensis 1.2%, cooked Radix Notoginseng 1.5%, Stigma Croci 0.5%, lavandula angustifolia 2.3% Semen Persicae 0.5%, Radix Polygalae 1.5%, Ganoderma sinense Zhao Xu et Zhang 0.5%, Radix Rhodiolae 0.5%, the Radix Polygoni Multiflori 2.5% that wine is processed, the Rhizoma Polygonati 0.5% that wine is processed, Radix Sophorae Flavescentis 0.5%, Fructus Cnidii 0.5%, Rhizoma Smilacis Glabrae 0.5%, Radix Aconiti Lateralis Preparata 1.5%, Borneolum Syntheticum 1.5%, Rhizoma Polygonati Odorati 0.5%, Flos Carthami 2.5%, Ramulus Mori 1.5%, Sanguis Draxonis 0.2%, Radix Angelicae Pubescentis 1.5%, Rhizoma Chuanxiong 1.5%, Ramulus Cinnamomi 0.5%, Fructus Gardeniae Preparatus 3.5%, Radix Scutellariae 2.5%, Cortex Phellodendri 3.5%, Herba Lycopodii 2.5%, the Radix Angelicae Dahuricae 2.5%, Poria 1.5%, Margarita 2.5%, Herba speranskiae tuberculatae 2.5%, Rhizoma Zingiberis 3.5%, Bulbus Lilii 0.5%, Semen Ziziphi Spinosae 2.5%, Radix Salviae Miltiorrhizae 2.5%, Radix Ginseng 0.2% and Magnetitum 1.5%.
3. the preparation method of medicine as described in claim 1 or 2, is characterized in that comprising the following steps:
(1) select raw material: choose the medical material of high-quality as raw material;
(2) clean: the medical material as raw material is cleaned;
(3) tentatively pulverize: the medical material after cleaning is tentatively pulverized through grinder;
(4) fermentation: will pave through the preliminary medical material uniform particles of pulverizing, spray to infiltrate with wine and ferment, obtain fermented product;
(5) cold drying: fermented product is carried out to oven drying at low temperature, obtain drying composite;
(6) fine gtinding: drying composite is ground to and is greater than or equal to 200 object fine powders, obtain drug products.
4. the preparation method of medicine according to claim 3, is characterized in that described preliminary pulverizing is for being ground to 80～120 object granules by the medical material after cleaning through grinder.
5. the preparation method of medicine according to claim 3, is characterized in that described fermentation sprays and infiltrate with 50～60 degree grain wine, stirring fermentation and within 7～15 days, carrying out enzyme zymolysis.
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| CN116712324B (en) * | 2023-04-27 | 2024-04-23 | 云南郑保制药有限公司 | Notoginseng moxibustion plaster |
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