CN103370610B - 用于等分冷冻样本的装置和方法 - Google Patents

用于等分冷冻样本的装置和方法 Download PDF

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Publication number
CN103370610B
CN103370610B CN201180057843.XA CN201180057843A CN103370610B CN 103370610 B CN103370610 B CN 103370610B CN 201180057843 A CN201180057843 A CN 201180057843A CN 103370610 B CN103370610 B CN 103370610B
Authority
CN
China
Prior art keywords
sample
frozen
frozen sample
location
aliquot
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201180057843.XA
Other languages
English (en)
Chinese (zh)
Other versions
CN103370610A (zh
Inventor
D·N·拉森
S·L·贝利奥
J·斯卢萨茨
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Charles Stark Draper Laboratory Inc
Harvard University
Original Assignee
Charles Stark Draper Laboratory Inc
Harvard University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Charles Stark Draper Laboratory Inc, Harvard University filed Critical Charles Stark Draper Laboratory Inc
Publication of CN103370610A publication Critical patent/CN103370610A/zh
Application granted granted Critical
Publication of CN103370610B publication Critical patent/CN103370610B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/08—Devices for withdrawing samples in the solid state, e.g. by cutting involving an extracting tool, e.g. core bit
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/42—Low-temperature sample treatment, e.g. cryofixation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
CN201180057843.XA 2010-12-01 2011-11-17 用于等分冷冻样本的装置和方法 Expired - Fee Related CN103370610B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41868810P 2010-12-01 2010-12-01
US61/418,688 2010-12-01
PCT/US2011/061214 WO2012074771A2 (en) 2010-12-01 2011-11-17 Apparatus and methods for aliquotting frozen samples

Publications (2)

Publication Number Publication Date
CN103370610A CN103370610A (zh) 2013-10-23
CN103370610B true CN103370610B (zh) 2016-08-10

Family

ID=45044753

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201180057843.XA Expired - Fee Related CN103370610B (zh) 2010-12-01 2011-11-17 用于等分冷冻样本的装置和方法

Country Status (8)

Country Link
US (1) US20140335554A1 (https=)
EP (1) EP2646792B1 (https=)
JP (2) JP2013545105A (https=)
CN (1) CN103370610B (https=)
AU (1) AU2011337043A1 (https=)
BR (1) BR112013013505A2 (https=)
CA (1) CA2819013C (https=)
WO (1) WO2012074771A2 (https=)

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US9032854B2 (en) * 2011-12-21 2015-05-19 Sakura Finetek U.S.A., Inc. Reciprocating microtome drive system
US9134202B2 (en) 2012-01-26 2015-09-15 Cryoxtract Instruments, Llc Robotic end effector for frozen aliquotter and methods of taking a frozen aliquot from biological samples
US20140267713A1 (en) * 2013-03-15 2014-09-18 Cryoxtract Instruments, Llc Machine Vision System for Frozen Aliquotter for Biological Samples
US20130286192A1 (en) * 2012-04-30 2013-10-31 Cryoxtract Instruments, Llc Machine Vision System for Frozen Aliquotter for Biological Samples
US12157595B2 (en) * 2012-05-03 2024-12-03 Vanrx Pharmasystems Inc. Cover removal system for use in controlled environment enclosures
US12065347B2 (en) * 2012-05-03 2024-08-20 Vanrx Pharmasystems Inc. Cover removal system for use in controlled environment enclosures
WO2014018681A2 (en) 2012-07-24 2014-01-30 Cryoxtract Instruments, Llc Apparatus and methods for aliquotting frozen samples
FI10181U1 (fi) 2013-04-17 2013-08-14 Konecranes Oyj Tarttuja kuormankäsittelylaitetta varten ja nosturi
EP2992311A1 (en) * 2013-05-04 2016-03-09 Cryoxtract Instruments, LLC Targeting systems and methods for frozen aliquotter for biological samples
CN103636737B (zh) * 2013-10-24 2016-05-11 杨公明 一种羊胎盘及羊水现场收集与保鲜的方法
US12392692B2 (en) 2017-03-09 2025-08-19 Hologic, Inc. Systems for automated preparation of biological specimens
BR112019015803B1 (pt) * 2017-03-09 2023-03-28 Hologic, Inc Sistema automatizado para processar uma amostra contida em um recipiente de amostras líquidas
CN107843453B (zh) * 2017-12-21 2024-01-23 上海泽泉科技股份有限公司 可调速手持低温样本分装仪
WO2019245906A1 (en) * 2018-06-20 2019-12-26 Gen-Probe Incorporated Method and apparatus for freezing dispensed droplets of liquid
ES2959019T3 (es) 2019-02-17 2024-02-19 National Scient And Technical Research Council Argentina Conicet Sistema de acceso a muestras biológicas en un vaso Dewar criogénico
CN113533762B (zh) * 2020-04-22 2025-10-24 深圳迎凯生物科技有限公司 试剂存储装置
CN111504691B (zh) * 2020-05-10 2023-03-10 淮阴师范学院 一种便携式地理信息采集装置
US11981473B2 (en) * 2020-09-27 2024-05-14 V Anrx Pharmasystems Inc. Cover removal system for use in controlled environment enclosures
CN116643025B (zh) * 2023-05-06 2024-04-02 中国地质大学（北京） 一种用于环境地质土壤检测的检测装置
CN117969196A (zh) * 2023-10-08 2024-05-03 四川国际旅行卫生保健中心(成都海关口岸门诊部) 一种无接触式粪便包虫的样本预处理设备
WO2025111515A1 (en) * 2023-11-22 2025-05-30 Mitegen, Llc Systems, methods, and devices for cryopreservation and recovery of cells and other biological materials

Citations (4)

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CN1950702A (zh) * 2003-10-31 2007-04-18 普拉斯马柯特有限公司 检定方法
WO2009123000A1 (ja) * 2008-03-31 2009-10-08 シスメックス株式会社 細胞処理装置、試料調製装置および細胞分析装置
CN101713784A (zh) * 2008-10-06 2010-05-26 希森美康株式会社 检体处理装置、检体搬送装置以及检体搬送方法
CN101726609A (zh) * 2008-10-28 2010-06-09 希森美康株式会社 标本分析仪

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JPS6166944A (ja) * 1984-09-11 1986-04-05 Nitsuteku Eng:Kk 血清試料の秤取方法及びその装置
US6117130A (en) * 1998-09-24 2000-09-12 Abiomed, Inc. Coring device for myocardial revascularization
TW388790B (en) * 1999-04-13 2000-05-01 Inst Of Unclear Energy Res Roc An automatic sampling method and facility for the heterogeneous materials
US20040085443A1 (en) * 2000-12-13 2004-05-06 Kallioniemi Olli P Method and system for processing regions of interest for objects comprising biological material
US20020129975A1 (en) * 2001-01-17 2002-09-19 Barta Ernest G. Ice auger system
US6635414B2 (en) * 2001-05-22 2003-10-21 Integrated Biosystems, Inc. Cryopreservation system with controlled dendritic freezing front velocity
JP4451263B2 (ja) * 2004-10-13 2010-04-14 エーザイ・アール・アンド・ディー・マネジメント株式会社 試料摘出装置
WO2007084483A2 (en) * 2006-01-13 2007-07-26 President And Fellows Of Harvard College Systems, methods, and devices for frozen sample distribution
US7823818B2 (en) * 2007-10-17 2010-11-02 Max-Planck-Gessellschaft zur Foerderung der Wissenschafter E.V. System and method for producing weighed portions of powder from at least one biological material at cryotemperatures

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1950702A (zh) * 2003-10-31 2007-04-18 普拉斯马柯特有限公司 检定方法
WO2009123000A1 (ja) * 2008-03-31 2009-10-08 シスメックス株式会社 細胞処理装置、試料調製装置および細胞分析装置
CN101713784A (zh) * 2008-10-06 2010-05-26 希森美康株式会社 检体处理装置、检体搬送装置以及检体搬送方法
CN101726609A (zh) * 2008-10-28 2010-06-09 希森美康株式会社 标本分析仪

Also Published As

Publication number Publication date
EP2646792B1 (en) 2019-07-10
CA2819013C (en) 2020-04-14
EP2646792A2 (en) 2013-10-09
WO2012074771A2 (en) 2012-06-07
CN103370610A (zh) 2013-10-23
US20140335554A1 (en) 2014-11-13
BR112013013505A2 (pt) 2016-09-06
WO2012074771A3 (en) 2012-08-16
JP2013545105A (ja) 2013-12-19
JP2016122018A (ja) 2016-07-07
CA2819013A1 (en) 2012-06-07
AU2011337043A1 (en) 2013-06-13

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Granted publication date: 20160810

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CF01 Termination of patent right due to non-payment of annual fee