JP2013545105A - 凍結試料をアリコートするための装置および方法 - Google Patents
凍結試料をアリコートするための装置および方法 Download PDFInfo
- Publication number
- JP2013545105A JP2013545105A JP2013542034A JP2013542034A JP2013545105A JP 2013545105 A JP2013545105 A JP 2013545105A JP 2013542034 A JP2013542034 A JP 2013542034A JP 2013542034 A JP2013542034 A JP 2013542034A JP 2013545105 A JP2013545105 A JP 2013545105A
- Authority
- JP
- Japan
- Prior art keywords
- sample
- frozen
- frozen sample
- coring
- core
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- 238000000034 method Methods 0.000 title claims abstract description 37
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- 239000000126 substance Substances 0.000 claims abstract description 31
- 238000004140 cleaning Methods 0.000 claims description 71
- 230000007246 mechanism Effects 0.000 claims description 44
- 238000007689 inspection Methods 0.000 claims description 36
- 239000012530 fluid Substances 0.000 claims description 18
- 210000004027 cell Anatomy 0.000 claims description 16
- 210000002381 plasma Anatomy 0.000 claims description 10
- 210000002966 serum Anatomy 0.000 claims description 10
- 230000005670 electromagnetic radiation Effects 0.000 claims description 9
- 238000005452 bending Methods 0.000 claims description 8
- -1 cell homogenates Substances 0.000 claims description 7
- 230000008602 contraction Effects 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 5
- 230000003287 optical effect Effects 0.000 claims description 5
- 239000000725 suspension Substances 0.000 claims description 5
- 210000004369 blood Anatomy 0.000 claims description 4
- 239000008280 blood Substances 0.000 claims description 4
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims description 4
- 210000000056 organ Anatomy 0.000 claims description 4
- 239000000243 solution Substances 0.000 claims description 4
- 210000002700 urine Anatomy 0.000 claims description 4
- 206010003445 Ascites Diseases 0.000 claims description 3
- 210000004381 amniotic fluid Anatomy 0.000 claims description 3
- 230000015556 catabolic process Effects 0.000 claims description 3
- 238000005336 cracking Methods 0.000 claims description 3
- 238000006731 degradation reaction Methods 0.000 claims description 3
- 210000004700 fetal blood Anatomy 0.000 claims description 3
- 238000003384 imaging method Methods 0.000 claims description 3
- 210000001589 microsome Anatomy 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- 210000003097 mucus Anatomy 0.000 claims description 3
- 108020004707 nucleic acids Proteins 0.000 claims description 3
- 102000039446 nucleic acids Human genes 0.000 claims description 3
- 150000007523 nucleic acids Chemical class 0.000 claims description 3
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- 210000000582 semen Anatomy 0.000 claims description 3
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- 240000001980 Cucurbita pepo Species 0.000 claims 1
- 235000009852 Cucurbita pepo Nutrition 0.000 claims 1
- 210000004102 animal cell Anatomy 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 239000012620 biological material Substances 0.000 claims 1
- 239000013592 cell lysate Substances 0.000 claims 1
- 239000006285 cell suspension Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 238000006073 displacement reaction Methods 0.000 claims 1
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- 235000020354 squash Nutrition 0.000 claims 1
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- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 8
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 6
- 238000005406 washing Methods 0.000 description 6
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- 210000002345 respiratory system Anatomy 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 239000000443 aerosol Substances 0.000 description 1
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- 230000009286 beneficial effect Effects 0.000 description 1
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- 239000011248 coating agent Substances 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 239000002826 coolant Substances 0.000 description 1
- 238000005138 cryopreservation Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 239000003517 fume Substances 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
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Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
- G01N1/08—Devices for withdrawing samples in the solid state, e.g. by cutting involving an extracting tool, e.g. core bit
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/42—Low-temperature sample treatment, e.g. cryofixation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Sampling And Sample Adjustment (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41868810P | 2010-12-01 | 2010-12-01 | |
| US61/418,688 | 2010-12-01 | ||
| PCT/US2011/061214 WO2012074771A2 (en) | 2010-12-01 | 2011-11-17 | Apparatus and methods for aliquotting frozen samples |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016071584A Division JP2016122018A (ja) | 2010-12-01 | 2016-03-31 | 凍結試料をアリコートするための装置および方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013545105A true JP2013545105A (ja) | 2013-12-19 |
| JP2013545105A5 JP2013545105A5 (https=) | 2015-01-15 |
Family
ID=45044753
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013542034A Pending JP2013545105A (ja) | 2010-12-01 | 2011-11-17 | 凍結試料をアリコートするための装置および方法 |
| JP2016071584A Pending JP2016122018A (ja) | 2010-12-01 | 2016-03-31 | 凍結試料をアリコートするための装置および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016071584A Pending JP2016122018A (ja) | 2010-12-01 | 2016-03-31 | 凍結試料をアリコートするための装置および方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20140335554A1 (https=) |
| EP (1) | EP2646792B1 (https=) |
| JP (2) | JP2013545105A (https=) |
| CN (1) | CN103370610B (https=) |
| AU (1) | AU2011337043A1 (https=) |
| BR (1) | BR112013013505A2 (https=) |
| CA (1) | CA2819013C (https=) |
| WO (1) | WO2012074771A2 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022528209A (ja) * | 2019-02-17 | 2022-06-08 | ナショナル・サイエンティフィック・アンド・テクニカル・リサーチ・カウンシル-アージェンティーナ(セーオーエネイーセーエーテー) | 極低温デュワ容器内の生物学的サンプルにアクセスするためのシステム |
| JP2024153623A (ja) * | 2017-03-09 | 2024-10-29 | ホロジック, インコーポレイテッド | 生物学的検体の自動調製システム及び方法 |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9032854B2 (en) | 2011-12-21 | 2015-05-19 | Sakura Finetek U.S.A., Inc. | Reciprocating microtome drive system |
| US9134202B2 (en) | 2012-01-26 | 2015-09-15 | Cryoxtract Instruments, Llc | Robotic end effector for frozen aliquotter and methods of taking a frozen aliquot from biological samples |
| US20140267713A1 (en) * | 2013-03-15 | 2014-09-18 | Cryoxtract Instruments, Llc | Machine Vision System for Frozen Aliquotter for Biological Samples |
| US20130286192A1 (en) * | 2012-04-30 | 2013-10-31 | Cryoxtract Instruments, Llc | Machine Vision System for Frozen Aliquotter for Biological Samples |
| US12157595B2 (en) * | 2012-05-03 | 2024-12-03 | Vanrx Pharmasystems Inc. | Cover removal system for use in controlled environment enclosures |
| US12065347B2 (en) * | 2012-05-03 | 2024-08-20 | Vanrx Pharmasystems Inc. | Cover removal system for use in controlled environment enclosures |
| BR112015001460A2 (pt) * | 2012-07-24 | 2017-07-04 | Cryoxtract Instr Llc | sonda de escavação, sistemas para colher núcleo de amostras congelados de uma pluralidade de amostras congeladas, para coletar alíquotas congeladas de amostras biológicas congeladas contidas em contêineres de amostras, para armazenar amostras de tecido congeladas, métodos de colher um núcleo de amostra congelada de uma amostra congelada, para aumentar a probabilidade de um operador usar apenas as sondas de escavação, para preparar e amostrar uma amostra de tecido em um contêiner de amostra de tecido, e de armazenamento de uma amostra de tecido, dispositivo portátil de escavação, bandeja, contêiner de amostra de tecido, kit para preparação de u,a a,ostra de tecido, transporte de tecido para suportar a amostra de tecido, e, combinação de transporte de tecido e dispositivo de escavação. |
| FI10181U1 (fi) * | 2013-04-17 | 2013-08-14 | Konecranes Oyj | Tarttuja kuormankäsittelylaitetta varten ja nosturi |
| AU2014262888A1 (en) * | 2013-05-04 | 2015-11-19 | Cryoxtract Instruments, Llc | Targeting systems and methods for frozen aliquotter for biological samples |
| CN103636737B (zh) * | 2013-10-24 | 2016-05-11 | 杨公明 | 一种羊胎盘及羊水现场收集与保鲜的方法 |
| US12392692B2 (en) | 2017-03-09 | 2025-08-19 | Hologic, Inc. | Systems for automated preparation of biological specimens |
| CN107843453B (zh) * | 2017-12-21 | 2024-01-23 | 上海泽泉科技股份有限公司 | 可调速手持低温样本分装仪 |
| EP3811007A1 (en) * | 2018-06-20 | 2021-04-28 | Gen-Probe Incorporated | Method and apparatus for freezing dispensed droplets of liquid |
| CN113533762B (zh) * | 2020-04-22 | 2025-10-24 | 深圳迎凯生物科技有限公司 | 试剂存储装置 |
| CN111504691B (zh) * | 2020-05-10 | 2023-03-10 | 淮阴师范学院 | 一种便携式地理信息采集装置 |
| US11981473B2 (en) * | 2020-09-27 | 2024-05-14 | V Anrx Pharmasystems Inc. | Cover removal system for use in controlled environment enclosures |
| CN116643025B (zh) * | 2023-05-06 | 2024-04-02 | 中国地质大学(北京) | 一种用于环境地质土壤检测的检测装置 |
| CN117969196A (zh) * | 2023-10-08 | 2024-05-03 | 四川国际旅行卫生保健中心(成都海关口岸门诊部) | 一种无接触式粪便包虫的样本预处理设备 |
| WO2025111514A1 (en) * | 2023-11-22 | 2025-05-30 | Mitegen, Llc | Systems, methods, and devices for rapid warming of cells and other biological materials |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0360390B2 (https=) * | 1984-09-11 | 1991-09-13 | Nittec Co Ltd | |
| JP2000304664A (ja) * | 1999-04-13 | 2000-11-02 | Inst Nuclear Energy Research Rocaec | 非均質性固体原料の試料採取方法及び装置 |
| JP2006112847A (ja) * | 2004-10-13 | 2006-04-27 | Eisai Co Ltd | 試料摘出装置 |
| US20090101738A1 (en) * | 2007-10-17 | 2009-04-23 | Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E. V . | System and method for producing weighed portions of powder from at least one biological material at cryotemperatures |
| JP2009524021A (ja) * | 2006-01-13 | 2009-06-25 | プレジデント・アンド・フエローズ・オブ・ハーバード・カレツジ | 凍結標本の分配システム、方法及び装置 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6117130A (en) * | 1998-09-24 | 2000-09-12 | Abiomed, Inc. | Coring device for myocardial revascularization |
| US20040085443A1 (en) * | 2000-12-13 | 2004-05-06 | Kallioniemi Olli P | Method and system for processing regions of interest for objects comprising biological material |
| US20020129975A1 (en) * | 2001-01-17 | 2002-09-19 | Barta Ernest G. | Ice auger system |
| US6635414B2 (en) * | 2001-05-22 | 2003-10-21 | Integrated Biosystems, Inc. | Cryopreservation system with controlled dendritic freezing front velocity |
| GB0325483D0 (en) * | 2003-10-31 | 2003-12-03 | Plasmacute As | Assay |
| EP2261632B1 (en) * | 2008-03-31 | 2019-09-11 | Sysmex Corporation | Sample preparation device, and cell analyzing device with the same |
| JP5530613B2 (ja) * | 2008-10-06 | 2014-06-25 | シスメックス株式会社 | 検体処理システム及び検体搬送システム |
| JP5203889B2 (ja) * | 2008-10-28 | 2013-06-05 | シスメックス株式会社 | 検体分析装置及び検体分析方法 |
-
2011
- 2011-11-17 AU AU2011337043A patent/AU2011337043A1/en not_active Abandoned
- 2011-11-17 EP EP11788311.6A patent/EP2646792B1/en not_active Not-in-force
- 2011-11-17 CA CA2819013A patent/CA2819013C/en not_active Expired - Fee Related
- 2011-11-17 WO PCT/US2011/061214 patent/WO2012074771A2/en not_active Ceased
- 2011-11-17 US US13/991,103 patent/US20140335554A1/en not_active Abandoned
- 2011-11-17 BR BR112013013505A patent/BR112013013505A2/pt not_active Application Discontinuation
- 2011-11-17 CN CN201180057843.XA patent/CN103370610B/zh not_active Expired - Fee Related
- 2011-11-17 JP JP2013542034A patent/JP2013545105A/ja active Pending
-
2016
- 2016-03-31 JP JP2016071584A patent/JP2016122018A/ja active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0360390B2 (https=) * | 1984-09-11 | 1991-09-13 | Nittec Co Ltd | |
| JP2000304664A (ja) * | 1999-04-13 | 2000-11-02 | Inst Nuclear Energy Research Rocaec | 非均質性固体原料の試料採取方法及び装置 |
| JP2006112847A (ja) * | 2004-10-13 | 2006-04-27 | Eisai Co Ltd | 試料摘出装置 |
| JP2009524021A (ja) * | 2006-01-13 | 2009-06-25 | プレジデント・アンド・フエローズ・オブ・ハーバード・カレツジ | 凍結標本の分配システム、方法及び装置 |
| US20090101738A1 (en) * | 2007-10-17 | 2009-04-23 | Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E. V . | System and method for producing weighed portions of powder from at least one biological material at cryotemperatures |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2024153623A (ja) * | 2017-03-09 | 2024-10-29 | ホロジック, インコーポレイテッド | 生物学的検体の自動調製システム及び方法 |
| JP7806134B2 (ja) | 2017-03-09 | 2026-01-26 | ホロジック, インコーポレイテッド | 生物学的検体の自動調製システム及び方法 |
| JP2022528209A (ja) * | 2019-02-17 | 2022-06-08 | ナショナル・サイエンティフィック・アンド・テクニカル・リサーチ・カウンシル-アージェンティーナ(セーオーエネイーセーエーテー) | 極低温デュワ容器内の生物学的サンプルにアクセスするためのシステム |
| JP7688587B2 (ja) | 2019-02-17 | 2025-06-04 | ナショナル・サイエンティフィック・アンド・テクニカル・リサーチ・カウンシル-アージェンティーナ(セーオーエネイーセーエーテー) | 極低温デュワ容器内の生物学的サンプルにアクセスするためのシステム |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2819013C (en) | 2020-04-14 |
| AU2011337043A1 (en) | 2013-06-13 |
| EP2646792A2 (en) | 2013-10-09 |
| US20140335554A1 (en) | 2014-11-13 |
| EP2646792B1 (en) | 2019-07-10 |
| BR112013013505A2 (pt) | 2016-09-06 |
| CA2819013A1 (en) | 2012-06-07 |
| CN103370610A (zh) | 2013-10-23 |
| WO2012074771A3 (en) | 2012-08-16 |
| JP2016122018A (ja) | 2016-07-07 |
| CN103370610B (zh) | 2016-08-10 |
| WO2012074771A2 (en) | 2012-06-07 |
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