CN103293034B - Full-automatic pathological tissue moviemaking system - Google Patents
Full-automatic pathological tissue moviemaking system Download PDFInfo
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- CN103293034B CN103293034B CN201210042736.6A CN201210042736A CN103293034B CN 103293034 B CN103293034 B CN 103293034B CN 201210042736 A CN201210042736 A CN 201210042736A CN 103293034 B CN103293034 B CN 103293034B
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Abstract
The invention belongs to technical field of medical instruments, design a kind of moviemaking system, especially relate to a kind of full-automatic pathological tissue moviemaking system.It solve in prior art functions such as can not being polymerized marking, baking sheet, dyeing and cover plate to be integrated, the technical matterss such as film-making efficiency is low, slice-making quality difference.This full-automatic pathological tissue moviemaking system, comprise some slide positioning tables for placing slide, each slide positioning table is all arranged on slide transmitting device, is provided with uploading device, marking glue spreading apparatus, hot pressing baking sheet dewaxing device successively, drips dye device, cover plate device and download apparatus above slide transmitting device along the transmission direction of slide positioning table.It is high that the present invention has film-making efficiency, and slice-making quality is good, can gather the functions such as marking gluing, hot pressing baking sheet, dewaxing dyeing and mounting roll extrusion in one, is conducive to realizing the advantages such as pathological tissue batch film-making function.
Description
Technical field
The invention belongs to technical field of medical instruments, relate to a kind of moviemaking system, especially relate to a kind of full-automatic pathological tissue moviemaking system.
Background technology
In medical treatment and biological study occasion, often need to carry out film-making, dyeing to cell specimen, traditional film-making is by cotton swab or Uterine neck bush or scraper plate collection cell, then brushes on microslide, then microslide is put into immobile liquid.This mode not only structure of cell, form is unclear, blurred background, the easy observation affecting doctor, and most cells is still stayed on cotton swab or Uterine neck bush or scraper plate, the cell be transferred on microslide is not representative, make cell accumulation, overlap, obstruct the view, the accuracy that impact checks.Due to the film-making of pathological tissue cell and the second-rate of dyeing, make the medical analysis report of pathological tissue not accurate enough, badly influence the judgement of doctor to pathological diagnosis method, good treatment effect can not be reached.
In order to solve prior art Problems existing, people have carried out long-term exploration, propose solution miscellaneous, nowadays adopt the automatic film-making of cell chip preparing machine to obtain applying more and more widely.Such as, Chinese patent literature discloses a kind of dyeing machine for natural sedimentation liquid based cell slice [application number: 200920051732.8], comprise sampling mechanism, sample containing mechanism, slide holds seat, dyeing liquor injecting mechanism, dye pin up-down mechanism, lower shoe, control circuit, described sampling mechanism is positioned at the top of lower shoe, and described sampling mechanism comprises horicontal motion mechanism and vertical motion mechanism; Horicontal motion mechanism comprise horizontal positioned guide rail, can along the side-to-side movement block of slide, drive the synchronous pulley laying respectively at guide rail two ends of the Timing Belt of described side-to-side movement block, supporting Timing Belt, drive the motor of Timing Belt.
Such scheme improves prior art to a certain extent, ensure that cell is complete, prevents cell accumulation, improves the quality gathering cell sample, makes cell distribution even, is convenient to observe and diagnosis.But its structure is still comparatively complicated, the functions such as the marking in pathological tissue moviemaking system, baking sheet, dyeing and cover plate can not be combined together, be difficult to carry out batch film-making dyeing operation, and film-making efficiency be comparatively low.
Summary of the invention
The object of the invention is for the problems referred to above, there is provided a kind of reasonable in design, structure is simple, film-making efficiency is high, slice-making quality good, the functions such as the marking gluing in pathological tissue moviemaking system, hot pressing baking sheet, dewaxing dyeing and mounting roll extrusion can be gathered in one, adopt the full-automatic pathological tissue moviemaking system that pipeline system process is cut into slices.
For achieving the above object, present invention employs following technical proposal: this full-automatic pathological tissue moviemaking system, comprise some slide positioning tables for placing slide, each slide positioning table is all arranged on slide transmitting device and this slide transmitting device can circle transmission each slide positioning table above-mentioned, the uploading device for loading slide is provided with successively along the transmission direction of slide positioning table above slide transmitting device, for carrying out the marking glue spreading apparatus of marking gluing to slide, sheet dewaxing device is dried in hot pressing for dewaxing to slide, dye device is dripped for what dye to slide, for carrying out the cover plate device of mounting roll extrusion and the download apparatus for making slide depart from slide positioning table to slide.
In above-mentioned full-automatic pathological tissue moviemaking system, described slide transmitting device comprises some live-rollers and is located at the driving-belt on live-roller, one of them live-roller is connected with the driver that it can be driven to rotate in a circumferential direction, and described slide positioning table is arranged on the belt.
Further, in above-mentioned full-automatic pathological tissue moviemaking system, described hot pressing is dried sheet dewaxing device and is comprised for carrying the suction paraffin paper conveying mechanism inhaling paraffin paper and the heating arrangements be located at directly over slide positioning table, between slide positioning table and heating arrangements, form the gap for inhaling paraffin paper process, described heating arrangements with can drive its vertical lifting thus heating arrangements is connected inhaling the lift drive mechanism that paraffin paper is pressed on slide.
In above-mentioned full-automatic pathological tissue moviemaking system, described suction paraffin paper conveying mechanism comprises the blowing seat and drives structure that are separately positioned on slide positioning table both sides, is provided with some transfer rollers between described blowing seat and drives structure.
In above-mentioned full-automatic pathological tissue moviemaking system, described drives structure comprises the drive roll and driven voller that are disposed adjacent, described drive roll and driven voller outer rim tangent, described heating arrangements is constant temperature electric heating mechanism.
Further, in above-mentioned full-automatic pathological tissue moviemaking system, the described dye device that drips comprises reagent transfer pipeline, reagent transfer pipeline is connected with reagent storage mechanism, is arranged with reagent heated at constant temperature mechanism at the outer of reagent transfer pipeline.
In above-mentioned full-automatic pathological tissue moviemaking system, described reagent heated at constant temperature mechanism comprises the heated at constant temperature case for storing heated at constant temperature liquid, described reagent transfer pipeline comprises some reagent delivery pipes be set up in parallel, the upper end of reagent delivery pipe is connected with reagent storage mechanism and the middle part of reagent delivery pipe is bending, the lower end of reagent delivery pipe passes heated at constant temperature case, valve is provided with between reagent delivery pipe and reagent storage mechanism, described reagent storage mechanism comprises some reagent barrels, described reagent barrel is connected correspondingly with reagent delivery pipe.
As a kind of technical scheme comparatively optimized, in above-mentioned full-automatic pathological tissue moviemaking system, described cover plate device comprises the roll extrusion part with arc surface, being provided with in one end of roll extrusion part and roll extrusion part can be driven to carry out the driving mechanism rolled, being provided with the position-limit mechanism for limiting roll extrusion part rolling amplitude at the other end of roll extrusion part.
In above-mentioned full-automatic pathological tissue moviemaking system, described driving mechanism comprises first connecting rod and second connecting rod, one end of described first connecting rod is connected with the driver that it can be driven to rotate in a circumferential direction, one end of the other end and second connecting rod is hinged, and the other end of described second connecting rod and one end of roll extrusion part are hinged.
In above-mentioned full-automatic pathological tissue moviemaking system, described position-limit mechanism comprises block, third connecting rod and extension spring, described third connecting rod one end is articulated with hinged seat, one end of the other end and roll extrusion part is hinged, described block is fixed on the side of third connecting rod, one end of described extension spring is connected with third connecting rod, and the other end is connected with block.
Compared with prior art, the advantage of this full-automatic pathological tissue moviemaking system is: reasonable in design, structure is simple, film-making efficiency is high, slice-making quality good, the functions such as the marking gluing in pathological tissue moviemaking system, hot pressing baking sheet, dewaxing dyeing and mounting roll extrusion can be gathered in one, be particularly conducive to the function realizing the film-making of pathological tissue batch.
Accompanying drawing explanation
Fig. 1 is structural representation provided by the invention.
Fig. 2 is the structural representation that sheet dewaxing device is dried in hot pressing provided by the invention.
Fig. 3 is the structural representation of provided by the invention dye device.
Fig. 4 is the structural representation of cover plate device provided by the invention.
In figure, slide 1, slide positioning table 2, slide transmitting device 3, power wheel 31, driving-belt 32, uploading device 4, marking glue spreading apparatus 5, sheet dewaxing device 6 is dried in hot pressing, inhale paraffin paper 61, inhale paraffin paper conveying mechanism 62, heating arrangements 63, gap 64, blowing seat 65, drives structure 66, drive roll 661, driven voller 662, transfer roller 67, drip dye device 7, reagent transfer pipeline 71, reagent storage mechanism 72, reagent barrel 721, reagent heated at constant temperature mechanism 73, heated at constant temperature case 74, reagent delivery pipe 75, valve 76, cover plate device 8, rolling member 81, arc surface 811, driving mechanism 82, first connecting rod 821, second connecting rod 822, position-limit mechanism 83, baffle plate 831, second connecting rod 832, extension spring 833, hinged seat 84, download apparatus 9.
Embodiment
Below in conjunction with the drawings and specific embodiments, the present invention will be further described in detail.
As shown in Figure 1, this full-automatic pathological tissue moviemaking system, comprise some slide positioning tables 2 for placing slide 1, each slide positioning table 2 is all arranged on slide transmitting device 3 and this slide transmitting device 3 can circle transmission each slide positioning table 2 above-mentioned, the uploading device 4 for loading slide 1 is provided with successively along the transmission direction of slide positioning table 2 above slide transmitting device 3, for carrying out the marking glue spreading apparatus 5 of marking gluing to slide 1, sheet dewaxing device 6 is dried in hot pressing for dewaxing to slide 1, dye device 7 is dripped for what dye to slide 1, for carrying out the cover plate device 8 of mounting roll extrusion and the download apparatus 9 for making slide 1 depart from slide positioning table 2 to slide 1.
The driving-belt 32 that slide transmitting device 3 in the present embodiment comprises some live-rollers 31 and is located on live-roller 31, one of them live-roller 31 is connected with the driver that it can be driven to rotate in a circumferential direction, and slide positioning table 2 is arranged on driving-belt 32.When driver drives live-roller 31 rotates in a circumferential direction, other live-rollers rotate in a circumferential direction under the traction of driving-belt 32, thus reaching the effect of circle transmission slide positioning table 2, slide transmitting device 3 here can need according to actual transmissions the frame mode taking multiple various kinds.
As shown in Figure 2, hot pressing is dried sheet dewaxing device 6 and is comprised for carrying the suction paraffin paper conveying mechanism 62 inhaling paraffin paper 61 and the heating arrangements 63 be located at directly over slide positioning table 2, the gap 64 for inhaling paraffin paper 61 process is formed between slide positioning table 2 and heating arrangements 63, heating arrangements 63 with can drive its vertical lifting thus heating arrangements 63 is connected inhaling the lift drive mechanism that paraffin paper 61 is pressed on slide 1, inhale paraffin paper conveying mechanism 62 and comprise the blowing seat 65 and drives structure 66 that are separately positioned on slide positioning table 2 both sides, some transfer rollers 67 are provided with between blowing seat 65 and drives structure 66, drives structure 66 comprises the drive roll 661 and driven voller 662 that are disposed adjacent, drive roll 661 and driven voller 662 outer rim tangent, heating arrangements 63 is constant temperature electric heating mechanism.When suction paraffin paper 61 is pressed on slide 1 downwards by heating arrangements 63, paraffin melting being attracted on suction paraffin paper 61 on slide 1 is taken away, on slide 1, residual water is also sucked away simultaneously, slide 1 is more easily fixed on slide positioning table 2 in bake process, can save and dry the sheet time, improve and dry tablet quality.
As shown in Figure 3, drip dye device 7 and comprise reagent transfer pipeline 71, reagent transfer pipeline 71 is connected with reagent storage mechanism 72, is arranged with reagent heated at constant temperature mechanism 73 at the outer of reagent transfer pipeline 71.As a kind of technical scheme comparatively optimized, reagent heated at constant temperature mechanism 73 in the present embodiment comprises the heated at constant temperature case 74 for storing heated at constant temperature liquid, reagent transfer pipeline 71 comprises some reagent delivery pipes 75 be set up in parallel, the upper end of reagent delivery pipe 75 is connected with reagent storage mechanism 72 and the middle part of reagent delivery pipe 75 is bending, the lower end of reagent delivery pipe 75 passes heated at constant temperature case 74, valve 76 is provided with between reagent delivery pipe 75 and reagent storage mechanism 72, reagent storage mechanism 72 comprises some reagent barrels 721, reagent barrel 721 is connected correspondingly with reagent delivery pipe 75.Here the structure contaminating and need to take multiple various kinds can be dripped, as long as be conducive to reaching good Color according to reality in reagent transfer pipeline 71, reagent storage mechanism 72 and reagent heated at constant temperature mechanism 73.
As shown in Figure 4, cover plate device 8 comprises the roll extrusion part 81 with arc surface 811, be provided with in one end of roll extrusion part 81 and roll extrusion part 81 can be driven to carry out the driving mechanism 82 rolled, be provided with at the other end of roll extrusion part 81 and roll the position-limit mechanism 83 of amplitude for limiting roll extrusion part 81.Driving mechanism 82 comprises first connecting rod 821 and second connecting rod 822, one end of first connecting rod 821 is connected with the driver that it can be driven to rotate in a circumferential direction, one end of the other end and second connecting rod 822 is hinged, the other end of second connecting rod 822 and one end of roll extrusion part 81 are hinged, position-limit mechanism 83 comprises block 831, third connecting rod 832 and extension spring 833, third connecting rod 832 one end is articulated with hinged seat 84, one end of the other end and roll extrusion part 81 is hinged, block 831 is fixed on the side of third connecting rod 832, one end of extension spring 833 is connected with third connecting rod 832, the other end is connected with block 831.Here driving mechanism 82 and the structure of position-limit mechanism 83 can be selected according to actual needs, as long as be conducive to driving roll extrusion part 81 roll and can limit its rolling amplitude.
In this pathological tissue moviemaking system for load slide 1 uploading device 4, for carrying out the marking glue spreading apparatus 5 of marking gluing to slide 1 and the download apparatus 9 for making slide 1 depart from slide positioning table 2 all adopts existing conventional equipment to implement, and therefore not to repeat here.
Specific embodiment described herein is only to the explanation for example of the present invention's spirit.Those skilled in the art can make various amendment or supplement or adopt similar mode to substitute to described specific embodiment, but can't depart from spirit of the present invention or surmount the scope that appended claims defines.
Although more employ slide 1 herein, slide positioning table 2, slide transmitting device 3, power wheel 31, driving-belt 32, uploading device 4, marking glue spreading apparatus 5, sheet dewaxing device 6 is dried in hot pressing, inhale paraffin paper 61, inhale paraffin paper conveying mechanism 62, heating arrangements 63, gap 64, blowing seat 65, drives structure 66, drive roll 661, driven voller 662, transfer roller 67, drip dye device 7, reagent transfer pipeline 71, reagent storage mechanism 72, reagent barrel 721, reagent heated at constant temperature mechanism 73, heated at constant temperature case 74, reagent delivery pipe 75, valve 76, cover plate device 8, rolling member 81, arc surface 811, driving mechanism 82, first connecting rod 821, second connecting rod 822, position-limit mechanism 83, baffle plate 831, second connecting rod 832, extension spring 833, hinged seat 84, term such as download apparatus 9 grade, but do not get rid of the possibility using other term.These terms are used to be only used to describe and explain essence of the present invention more easily; The restriction that they are construed to any one additional is all contrary with spirit of the present invention.
Claims (10)
1. a full-automatic pathological tissue moviemaking system, it is characterized in that, this moviemaking system comprises some slide positioning tables (2) for placing slide (1), each slide positioning table (2) is all arranged on upper and this slide transmitting device (3) of slide transmitting device (3) can circle transmission each slide positioning table (2) above-mentioned, the uploading device (4) for loading slide (1) is provided with successively along the transmission direction of slide positioning table (2) in the top of slide transmitting device (3), for carrying out the marking glue spreading apparatus (5) of marking gluing to slide (1), sheet dewaxing device (6) is dried in hot pressing for dewaxing to slide (1), dye device (7) is dripped for what dye to slide (1), for carrying out the cover plate device (8) of mounting roll extrusion and the download apparatus (9) for making slide (1) depart from slide positioning table (2) to slide (1).
2. full-automatic pathological tissue moviemaking system according to claim 1, it is characterized in that, described slide transmitting device (3) comprises some live-rollers (31) and is located at the driving-belt (32) on live-roller (31), one of them live-roller (31) is connected with the driver that it can be driven to rotate in a circumferential direction, and described slide positioning table (2) is arranged on driving-belt (32).
3. full-automatic pathological tissue moviemaking system according to claim 1 and 2, it is characterized in that, described hot pressing is dried sheet dewaxing device (6) and is comprised for carrying the suction paraffin paper conveying mechanism (62) inhaling paraffin paper (61) and the heating arrangements (63) be located at directly over slide positioning table (2), the gap (64) for inhaling paraffin paper (61) process is formed between slide positioning table (2) and heating arrangements (63), described heating arrangements (63) with can drive its vertical lifting thus heating arrangements (63) is connected inhaling the lift drive mechanism that paraffin paper (61) is pressed on slide (1).
4. full-automatic pathological tissue moviemaking system according to claim 3, it is characterized in that, described suction paraffin paper conveying mechanism (62) comprises the blowing seat (65) and drives structure (66) that are separately positioned on slide positioning table (2) both sides, is provided with some transfer rollers (67) between described blowing seat (65) and drives structure (66).
5. full-automatic pathological tissue moviemaking system according to claim 4, it is characterized in that, described drives structure (66) comprises the drive roll (661) and driven voller (662) that are disposed adjacent, described drive roll (661) and driven voller (662) outer rim tangent, described heating arrangements (63) is constant temperature electric heating mechanism.
6. full-automatic pathological tissue moviemaking system according to claim 1 and 2, it is characterized in that, described dye device (7) of dripping comprises reagent transfer pipeline (71), reagent transfer pipeline (71) is connected with reagent storage mechanism (72), is arranged with reagent heated at constant temperature mechanism (73) at the outer of reagent transfer pipeline (71).
7. full-automatic pathological tissue moviemaking system according to claim 6, it is characterized in that, described reagent heated at constant temperature mechanism (73) comprises the heated at constant temperature case (74) for storing heated at constant temperature liquid, described reagent transfer pipeline (71) comprises some reagent delivery pipes (75) be set up in parallel, the upper end of reagent delivery pipe (75) is connected with reagent storage mechanism (72) and the middle part of reagent delivery pipe (75) is bending, the lower end of reagent delivery pipe (75) passes heated at constant temperature case (74), valve (76) is provided with between reagent delivery pipe (75) and reagent storage mechanism (72), described reagent storage mechanism (72) comprises some reagent barrels (721), described reagent barrel (721) is connected correspondingly with reagent delivery pipe (75).
8. full-automatic pathological tissue moviemaking system according to claim 1 and 2, it is characterized in that, described cover plate device (8) comprises the roll extrusion part (81) with arc surface (811), being provided with the driving mechanism (82) that roll extrusion part (81) can be driven to carry out rolling in one end of roll extrusion part (81), being provided with the position-limit mechanism (83) for limiting roll extrusion part (81) rolling amplitude at the other end of roll extrusion part (81).
9. full-automatic pathological tissue moviemaking system according to claim 8, it is characterized in that, described driving mechanism (82) comprises first connecting rod (821) and second connecting rod (822), one end of described first connecting rod (821) is connected with the driver that it can be driven to rotate in a circumferential direction, one end of the other end and second connecting rod (822) is hinged, and the other end of described second connecting rod (822) and one end of roll extrusion part (81) are hinged.
10. full-automatic pathological tissue moviemaking system according to claim 9, it is characterized in that, described position-limit mechanism (83) comprises block (831), third connecting rod (832) and extension spring (833), described third connecting rod (832) one end is articulated with hinged seat (84), one end of the other end and roll extrusion part (81) is hinged, described block (831) is fixed on the side of third connecting rod (832), one end of described extension spring (833) is connected with third connecting rod (832), and the other end is connected with block (831).
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| Application Number | Priority Date | Filing Date | Title |
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| CN201210042736.6A CN103293034B (en) | 2012-02-24 | 2012-02-24 | Full-automatic pathological tissue moviemaking system |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201210042736.6A CN103293034B (en) | 2012-02-24 | 2012-02-24 | Full-automatic pathological tissue moviemaking system |
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| CN103293034A CN103293034A (en) | 2013-09-11 |
| CN103293034B true CN103293034B (en) | 2015-09-02 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4067859A4 (en) * | 2019-11-26 | 2023-12-27 | Leica Biosystems Nussloch GmbH | Tissue treatment device |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103674651A (en) * | 2013-12-16 | 2014-03-26 | 王洪云 | Sealing hydraulic equipment used in pathological tissue slice preparation |
| CN105910864B (en) * | 2016-04-18 | 2019-05-10 | 佛山盈诺科创投资咨询中心（有限合伙） | A kind of smearing machine |
| CN115108244B (en) * | 2022-06-22 | 2024-01-26 | 四川金域医学检验中心有限公司 | Equipment suitable for pathological slide dries in air piece and preserves |
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| CN86207758U (en) * | 1986-09-27 | 1987-09-09 | 陈吉坤 | Specimen slice producing and dyeing apparatus |
| US6387326B1 (en) * | 1994-07-19 | 2002-05-14 | Fisher Scientific Company L.L.C. | Automated slide staining system and method thereof |
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