CN103293034A - Full-automatic pathological tissue slide-making system - Google Patents
Full-automatic pathological tissue slide-making system Download PDFInfo
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- CN103293034A CN103293034A CN2012100427366A CN201210042736A CN103293034A CN 103293034 A CN103293034 A CN 103293034A CN 2012100427366 A CN2012100427366 A CN 2012100427366A CN 201210042736 A CN201210042736 A CN 201210042736A CN 103293034 A CN103293034 A CN 103293034A
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Abstract
The invention belongs to the technical field of medical instruments, designs a slide-making system, and particularly relates to a full-automatic pathological tissue slide-making system. The full-automatic pathological tissue slide-making system solves the technical problems such as failure in integrating of functions of number marking, slide baking, dyeing and covering together, low slide-making efficiency and poor slide-making quality, of the existing technology. The full-automatic pathological tissue slide-making system comprises a plurality of slide locating tables for placing slides, wherein each slide locating table is arranged on a slide conveying device, and a loading device, a number marking gumming device, a hot-press slide baking dewaxing device, a drop dyeing device, a covering device and an unloading device are orderly arranged above the slide conveying device along the conveying direction of the slide locating tables. The full-automatic pathological tissue slide-making system has the advantages of being high in slide-making efficiency and excellent in slide-making quality, being capable of integrating the functions, such as number marking gumming, hot-press slide baking, dewaxing dyeing and slide sealing rolling, being beneficial to realizing a pathological tissue slide volume production function, and so on.
Description
Technical field
The invention belongs to technical field of medical instruments, relate to a kind of moviemaking system, especially relate to a kind of full-automatic pathological tissue moviemaking system.
Background technology
In medical treatment and biological study occasion, often need carry out film-making, dyeing to cell specimen, traditional film-making is by cotton swab or Uterine neck bush or scraper plate collection cell, brushes at microslide then, again microslide is put into immobile liquid.This mode not only structure, the form of cell is unclear, blurred background, influence doctor's observation easily, and most of cell is still stayed on cotton swab or Uterine neck bush or the scraper plate, the cell that is transferred on the microslide is not representative, make cell accumulation, overlapping, obstruct the view, the accuracy that influence checks.Because relatively poor to film-making and the dyeing quality of pathological tissue cell, feasible medical analysis report to pathological tissue is not accurate enough, badly influences the doctor to the judgement of pathological diagnosis method, can not reach good treatment effect.
In order to solve the problem that prior art exists, people have carried out long-term exploration, have proposed solution miscellaneous, nowadays adopt the automatic film-making of cell pelleter to obtain more and more widely application.For example, Chinese patent literature discloses a kind of natural subsidence liquid basal cell film-making overflow dyeing machine [application number: 200920051732.8], comprise that this mechanism of sampling, sample hold mechanism, slide holds seat, dyeing liquor injecting mechanism, dyeing pin up-down mechanism, lower shoe, control circuit, this mechanism of described sampling is positioned at the top of lower shoe, and this mechanism of described sampling comprises horicontal motion mechanism and vertical motion mechanism; Horicontal motion mechanism comprise the guide rail of horizontal positioned, the side-to-side movement piece that can slide along guide rail, the synchronous band that drives described side-to-side movement piece, supporting synchronously band the synchronous pulley that lays respectively at the guide rail two ends, drive the motor of band synchronously.
Such scheme has improved prior art to a certain extent, has guaranteed that cell is complete, has prevented cell accumulation, has improved the quality of gathering cell sample, makes cell distribution even, is convenient to observe and diagnosis.But its structure is still comparatively complicated, functions such as the marking in the pathological tissue moviemaking system, baking sheet, dyeing and cover plate can not be combined together, be difficult to carry out batch film-making dyeing operation, and film-making efficient is comparatively low.
Summary of the invention
The objective of the invention is at the problems referred to above, provide a kind of reasonable in design, simple in structure, film-making efficient height, slice-making quality are good, marking gluing, the hot pressing that can gather in the pathological tissue moviemaking system are dried by the fire functions such as sheet, dewaxing dyeing and mounting roll extrusion in one, adopt pipeline system to handle the full-automatic pathological tissue moviemaking system of cutting into slices.
For achieving the above object, the present invention has adopted following technical proposal: this full-automatic pathological tissue moviemaking system, comprise some for the slide positioning table of placing slide, each slide positioning table all is arranged on the slide transmitting device and this slide transmitting device can above-mentioned each slide positioning table of circle transmission, and the transmission direction along the slide positioning table above the slide transmitting device is provided with successively for the uploading device that loads slide, be used for slide is carried out the marking glue spreading apparatus of marking gluing, the sheet dewaxing device is dried by the fire in the hot pressing that is used for slide is dewaxed, be used for dripping of dyeing of slide dyed device, be used for slide is carried out the cover plate device of mounting roll extrusion and is used for making slide to break away from the download apparatus of slide positioning table.
In above-mentioned full-automatic pathological tissue moviemaking system, described slide transmitting device comprises some live-rollers and the driving-belt that is located on the live-roller, one of them live-roller with can drive its driver that rotates in a circumferential direction and be connected, described slide positioning table is arranged on the driving-belt.
Further, in above-mentioned full-automatic pathological tissue moviemaking system, described hot pressing baking sheet dewaxing device comprises for delivery of the suction paraffin paper conveying mechanism of inhaling paraffin paper and is located at heating arrangements directly over the slide positioning table, between slide positioning table and heating arrangements, form for the gap of inhaling the paraffin paper process, thus described heating arrangements with can drive its vertical lifting and make heating arrangements will inhale the lift drive mechanism that paraffin paper is pressed on the slide to be connected.
In above-mentioned full-automatic pathological tissue moviemaking system, described suction paraffin paper conveying mechanism comprises blowing seat and the drives structure that is separately positioned on slide positioning table both sides, is provided with some transfer rollers between described blowing seat and the drives structure.
In above-mentioned full-automatic pathological tissue moviemaking system, described drives structure comprises drive roll and the driven voller of adjacent setting, and described drive roll and driven voller outer rim are tangent, and described heating arrangements is constant temperature electrical heating mechanism.
Further, in above-mentioned full-automatic pathological tissue moviemaking system, described is dyed device and comprises the reagent transfer pipeline, is connected with reagent storage mechanism at the reagent transfer pipeline, is provided with reagent heated at constant temperature mechanism in the periphery of reagent transfer pipeline.
In above-mentioned full-automatic pathological tissue moviemaking system, described reagent heated at constant temperature mechanism comprises the heated at constant temperature case for storage heated at constant temperature liquid, described reagent transfer pipeline comprises some reagent delivery pipes that are set up in parallel, the upper end of reagent delivery pipe links to each other with reagent storage mechanism and the middle part of reagent delivery pipe is bending, the lower end of reagent delivery pipe passes the heated at constant temperature case, between reagent delivery pipe and reagent storage mechanism, be provided with valve, described reagent storage mechanism comprises some reagent buckets, and described reagent bucket is connected correspondingly with the reagent delivery pipe.
As a kind of technical scheme of comparatively optimizing, in above-mentioned full-automatic pathological tissue moviemaking system, described cover plate device comprises the roll extrusion part with arc surface, be provided with at an end of roll extrusion part and can drive the driving mechanism that the roll extrusion part rolls, be provided with position-limit mechanism for restriction roll extrusion part rolling amplitude at the other end of roll extrusion part.
In above-mentioned full-automatic pathological tissue moviemaking system, described driving mechanism comprises first connecting rod and second connecting rod, one end of described first connecting rod with can drive its driver that rotates in a circumferential direction and link to each other, one end of the other end and second connecting rod is hinged, and an end of the other end of described second connecting rod and roll extrusion part is hinged.
In above-mentioned full-automatic pathological tissue moviemaking system, described position-limit mechanism comprises block, third connecting rod and extension spring, described third connecting rod one end is articulated in hinged seat, one end of the other end and roll extrusion part is hinged, described block is fixed on a side of third connecting rod, one end of described extension spring links to each other with third connecting rod, and the other end links to each other with block.
Compared with prior art, the advantage of this full-automatic pathological tissue moviemaking system is: reasonable in design, simple in structure, film-making efficient height, slice-making quality are good, marking gluing, the hot pressing that can gather in the pathological tissue moviemaking system are dried by the fire functions such as sheet, dewaxing dyeing and mounting roll extrusion in one, are particularly conducive to and realize the pathological tissue function of film-making in batches.
Description of drawings
Fig. 1 is structural representation provided by the invention.
Fig. 2 is the structural representation of hot pressing baking sheet dewaxing device provided by the invention.
Fig. 3 is provided by the invention structural representation that dyes device.
Fig. 4 is the structural representation of cover plate device provided by the invention.
Among the figure, slide 1, slide positioning table 2, slide transmitting device 3, power wheel 31, driving-belt 32, uploading device 4, marking glue spreading apparatus 5, hot pressing baking sheet dewaxing device 6, inhale paraffin paper 61, inhale paraffin paper conveying mechanism 62, heating arrangements 63, gap 64, blowing seat 65, drives structure 66, drive roll 661, driven voller 662, transfer roller 67, drip and dye device 7, reagent transfer pipeline 71, reagent storage mechanism 72, reagent bucket 721, reagent heated at constant temperature mechanism 73, heated at constant temperature case 74, reagent delivery pipe 75, valve 76, cover plate device 8, rolling member 81, arc surface 811, driving mechanism 82, first connecting rod 821, second connecting rod 822, position-limit mechanism 83, baffle plate 831, second connecting rod 832, extension spring 833, hinged seat 84, download apparatus 9.
Embodiment
The present invention will be further described in detail below in conjunction with the drawings and specific embodiments.
As shown in Figure 1, this full-automatic pathological tissue moviemaking system, comprise some for the slide positioning table 2 of placing slide 1, each slide positioning table 2 all is arranged on the slide transmitting device 3 and this slide transmitting device 3 can above-mentioned each slide positioning table 2 of circle transmission, and the transmission direction along slide positioning table 2 above slide transmitting device 3 is provided with successively for the uploading device 4 that loads slide 1, be used for slide 1 is carried out the marking glue spreading apparatus 5 of marking gluing, sheet dewaxing device 6 is dried by the fire in the hot pressing that is used for slide 1 is dewaxed, be used for dripping of dyeing of slide 1 dyed device 7, be used for slide 1 is carried out the cover plate device 8 of mounting roll extrusion and is used for making slide 1 to break away from the download apparatus 9 of slide positioning table 2.
Slide transmitting device 3 in the present embodiment comprises some live-rollers 31 and is located at driving-belt 32 on the live-roller 31, one of them live-roller 31 with can drive its driver that rotates in a circumferential direction and be connected, slide positioning table 2 is arranged on the driving-belt 32.When live-roller 31 of driver drives rotates in a circumferential direction, other live-rollers are circumferentially rotation under the traction of driving-belt 32, thereby reach the effect of circle transmission slide positioning table 2, the slide transmitting device 3 here can be taked the frame mode of multiple various kinds according to the actual transmissions needs.
As shown in Figure 2, hot pressing baking sheet dewaxing device 6 comprises for delivery of the suction paraffin paper conveying mechanism 62 of inhaling paraffin paper 61 and is located at heating arrangements 63 directly over the slide positioning table 2, between slide positioning table 2 and heating arrangements 63, form for the gap 64 of inhaling paraffin paper 61 processes, thereby heating arrangements 63 with can drive its vertical lifting and make heating arrangements 63 will inhale the lift drive mechanism that paraffin paper 61 is pressed on the slide 1 to be connected, inhale paraffin paper conveying mechanism 62 and comprise blowing seat 65 and the drives structure 66 that is separately positioned on slide positioning table 2 both sides, be provided with some transfer rollers 67 between blowing seat 65 and the drives structure 66, drives structure 66 comprises drive roll 661 and the driven voller 662 of adjacent setting, drive roll 661 and driven voller 662 outer rims are tangent, and heating arrangements 63 is constant temperature electrical heating mechanism.When heating arrangements 63 will be inhaled paraffin paper 61 downwards and be pressed on the slide 1, paraffin on the slide 1 melts to be attracted to inhale on the paraffin paper 61 to be taken away, residual water also is sucked away on the slide 1 simultaneously, make slide 1 easier being fixed on the slide positioning table 2 in bake process, can save the baking sheet time, improve the baking tablet quality.
As shown in Figure 3, drip and to dye device 7 and comprise reagent transfer pipeline 71, be connected with reagent storage mechanism 72 at reagent transfer pipeline 71, be provided with reagent heated at constant temperature mechanism 73 in the periphery of reagent transfer pipeline 71.As a kind of technical scheme of comparatively optimizing, reagent heated at constant temperature mechanism 73 in the present embodiment comprises the heated at constant temperature case 74 for storage heated at constant temperature liquid, reagent transfer pipeline 71 comprises some reagent delivery pipes 75 that are set up in parallel, the upper end of reagent delivery pipe 75 links to each other with reagent storage mechanism 72 and the middle part of reagent delivery pipe 75 is bending, the lower end of reagent delivery pipe 75 passes heated at constant temperature case 74, between reagent delivery pipe 75 and reagent storage mechanism 72, be provided with valve 76, reagent storage mechanism 72 comprises some reagent buckets 721, and reagent bucket 721 is connected correspondingly with reagent delivery pipe 75.The reagent transfer pipeline 71 here, reagent storage mechanism 72 and reagent heated at constant temperature mechanism 73 can drip according to reality and dye the structure that needs are taked multiple various kinds, as long as be conducive to the Color that reaches good.
As shown in Figure 4, cover plate device 8 comprises the roll extrusion part 81 with arc surface 811, be provided with at an end of roll extrusion part 81 and can drive the driving mechanism 82 that roll extrusion part 81 rolls, be provided with position-limit mechanism 83 for restriction roll extrusion part 81 rolling amplitudes at the other end of roll extrusion part 81.Driving mechanism 82 comprises first connecting rod 821 and second connecting rod 822, one end of first connecting rod 821 with can drive its driver that rotates in a circumferential direction and link to each other, one end of the other end and second connecting rod 822 is hinged, one end of the other end of second connecting rod 822 and roll extrusion part 81 is hinged, position-limit mechanism 83 comprises block 831, third connecting rod 832 and extension spring 833, third connecting rod 832 1 ends are articulated in hinged seat 84, one end of the other end and roll extrusion part 81 is hinged, block 831 is fixed on a side of third connecting rod 832, one end of extension spring 833 links to each other with third connecting rod 832, and the other end links to each other with block 831.The driving mechanism 82 here and the structure of position-limit mechanism 83 can be selected according to actual needs, as long as be conducive to drive 81 rollings of roll extrusion part and can limit its rolling amplitude.
Be used for to load in this pathological tissue moviemaking system slide 1 uploading device 4, be used for slide 1 is carried out the marking glue spreading apparatus 5 of marking gluing and the download apparatus 9 that is used for making slide 1 break away from slide positioning table 2 all adopts existing conventional equipment to implement, so do not give unnecessary details at this.
Specific embodiment described herein only is that the present invention's spirit is illustrated.Those skilled in the art can make various modifications or replenish or adopt similar mode to substitute described specific embodiment, but can't depart from spirit of the present invention or surmount the defined scope of appended claims.
Although this paper has used slide 1 morely, slide positioning table 2, slide transmitting device 3, power wheel 31, driving-belt 32, uploading device 4, marking glue spreading apparatus 5, hot pressing baking sheet dewaxing device 6, inhale paraffin paper 61, inhale paraffin paper conveying mechanism 62, heating arrangements 63, gap 64, blowing seat 65, drives structure 66, drive roll 661, driven voller 662, transfer roller 67, drip and dye device 7, reagent transfer pipeline 71, reagent storage mechanism 72, reagent bucket 721, reagent heated at constant temperature mechanism 73, heated at constant temperature case 74, reagent delivery pipe 75, valve 76, cover plate device 8, rolling member 81, arc surface 811, driving mechanism 82, first connecting rod 821, second connecting rod 822, position-limit mechanism 83, baffle plate 831, second connecting rod 832, extension spring 833, hinged seat 84, download apparatus 9 terms such as grade, but do not get rid of the possibility of using other term.Using these terms only is in order to describe and explain essence of the present invention more easily; They are construed to any additional restriction all is contrary with spirit of the present invention.
Claims (10)
1. full-automatic pathological tissue moviemaking system, it is characterized in that, this moviemaking system comprises some for the slide positioning table (2) of placing slide (1), each slide positioning table (2) is arranged on all that slide transmitting device (3) is gone up and this slide transmitting device (3) can above-mentioned each slide positioning table (2) of circle transmission, and the transmission direction in the top of slide transmitting device (3) along slide positioning table (2) is provided with successively for the uploading device (4) that loads slide (1), be used for slide (1) is carried out the marking glue spreading apparatus (5) of marking gluing, sheet dewaxing device (6) is dried by the fire in the hot pressing that is used for slide (1) is dewaxed, be used for dripping of dyeing of slide (1) dyed device (7), be used for slide (1) is carried out the cover plate device (8) of mounting roll extrusion and is used for making slide (1) to break away from the download apparatus (9) of slide positioning table (2).
2. full-automatic pathological tissue moviemaking system according to claim 1, it is characterized in that, described slide transmitting device (3) comprises some live-rollers (31) and is located at driving-belt (32) on the live-roller (31), one of them live-roller (31) with can drive its driver that rotates in a circumferential direction and be connected, described slide positioning table (2) is arranged on the driving-belt (32).
3. full-automatic pathological tissue moviemaking system according to claim 1 and 2, it is characterized in that, described hot pressing baking sheet dewaxing device (6) comprises for delivery of the suction paraffin paper conveying mechanism (62) of inhaling paraffin paper (61) and is located at heating arrangements (63) directly over the slide positioning table (2), between slide positioning table (2) and heating arrangements (63), form for the gap (64) of inhaling paraffin paper (61) process, described heating arrangements (63) thus with can drive its vertical lifting and make heating arrangements (63) will inhale the lift drive mechanism that paraffin paper (61) is pressed on the slide (1) to be connected.
4. full-automatic pathological tissue moviemaking system according to claim 3, it is characterized in that, described suction paraffin paper conveying mechanism (62) comprises blowing seat (65) and the drives structure (66) that is separately positioned on slide positioning table (2) both sides, is provided with some transfer rollers (67) between described blowing seat (65) and the drives structure (66).
5. full-automatic pathological tissue moviemaking system according to claim 4, it is characterized in that, described drives structure (66) comprises drive roll (661) and the driven voller (662) of adjacent setting, described drive roll (661) and driven voller (662) outer rim are tangent, and described heating arrangements (63) is constant temperature electrical heating mechanism.
6. full-automatic pathological tissue moviemaking system according to claim 1 and 2, it is characterized in that, described is dyed device (7) and comprises reagent transfer pipeline (71), be connected with reagent storage mechanism (72) at reagent transfer pipeline (71), be provided with reagent heated at constant temperature mechanism (73) in the periphery of reagent transfer pipeline (71).
7. full-automatic pathological tissue moviemaking system according to claim 6, it is characterized in that, described reagent heated at constant temperature mechanism (73) comprises the heated at constant temperature case (74) for storage heated at constant temperature liquid, described reagent transfer pipeline (71) comprises some reagent delivery pipes (75) that are set up in parallel, the upper end of reagent delivery pipe (75) links to each other with reagent storage mechanism (72) and the middle part of reagent delivery pipe (75) is bending, the lower end of reagent delivery pipe (75) passes heated at constant temperature case (74), between reagent delivery pipe (75) and reagent storage mechanism (72), be provided with valve (76), described reagent storage mechanism (72) comprises some reagent buckets (721), and described reagent bucket (721) is connected correspondingly with reagent delivery pipe (75).
8. full-automatic pathological tissue moviemaking system according to claim 1 and 2, it is characterized in that, described cover plate device (8) comprises the have arc surface roll extrusion part (81) of (811), be provided with at an end of roll extrusion part (81) and can drive the driving mechanism (82) that roll extrusion part (81) rolls, be provided with position-limit mechanism (83) for restriction roll extrusion part (81) rolling amplitude at the other end of roll extrusion part (81).
9. full-automatic pathological tissue moviemaking system according to claim 8, it is characterized in that, described driving mechanism (82) comprises first connecting rod (821) and second connecting rod (822), one end of described first connecting rod (821) with can drive its driver that rotates in a circumferential direction and link to each other, one end of the other end and second connecting rod (822) is hinged, and an end of the other end of described second connecting rod (822) and roll extrusion part (81) is hinged.
10. full-automatic pathological tissue moviemaking system according to claim 9, it is characterized in that, described position-limit mechanism (83) comprises block (831), third connecting rod (832) and extension spring (833), described third connecting rod (832) one ends are articulated in hinged seat (84), one end of the other end and roll extrusion part (81) is hinged, described block (831) is fixed on a side of third connecting rod (832), one end of described extension spring (833) links to each other with third connecting rod (832), and the other end links to each other with block (831).
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| Application Number | Priority Date | Filing Date | Title |
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| CN201210042736.6A CN103293034B (en) | 2012-02-24 | 2012-02-24 | Full-automatic pathological tissue moviemaking system |
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| CN201210042736.6A CN103293034B (en) | 2012-02-24 | 2012-02-24 | Full-automatic pathological tissue moviemaking system |
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| CN103293034A true CN103293034A (en) | 2013-09-11 |
| CN103293034B CN103293034B (en) | 2015-09-02 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103674651A (en) * | 2013-12-16 | 2014-03-26 | 王洪云 | Sealing hydraulic equipment used in pathological tissue slice preparation |
| CN105910864A (en) * | 2016-04-18 | 2016-08-31 | 佛山盈诺科创投资咨询中心（有限合伙） | Smear machine |
| WO2021104258A1 (en) * | 2019-11-26 | 2021-06-03 | 莱卡生物系统努斯洛赫有限责任公司 | Tissue treatment device |
| CN115108244A (en) * | 2022-06-22 | 2022-09-27 | 四川金域医学检验中心有限公司 | Equipment suitable for pathological slide dries in air piece and preserves |
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| WO2021104258A1 (en) * | 2019-11-26 | 2021-06-03 | 莱卡生物系统努斯洛赫有限责任公司 | Tissue treatment device |
| CN115108244A (en) * | 2022-06-22 | 2022-09-27 | 四川金域医学检验中心有限公司 | Equipment suitable for pathological slide dries in air piece and preserves |
| CN115108244B (en) * | 2022-06-22 | 2024-01-26 | 四川金域医学检验中心有限公司 | Equipment suitable for pathological slide dries in air piece and preserves |
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| CN103293034B (en) | 2015-09-02 |
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