CN102297794A - Full automatic integrated liquid-based cytological smear making and dyeing machine and its application - Google Patents
Full automatic integrated liquid-based cytological smear making and dyeing machine and its application Download PDFInfo
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- CN102297794A CN102297794A CN2011102011083A CN201110201108A CN102297794A CN 102297794 A CN102297794 A CN 102297794A CN 2011102011083 A CN2011102011083 A CN 2011102011083A CN 201110201108 A CN201110201108 A CN 201110201108A CN 102297794 A CN102297794 A CN 102297794A
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Abstract
The invention provides a full automatic integrated liquid-based cytological smear making and dyeing machine which comprises a housing case and a loading device, a dyeing device and an auxiliary device arranged in the housing case, wherein, the housing case comprises a main body, a back blanking plate behind the main body and a face shield on the top of the main body, a display operation screen is provided above the front of the main body, the interior of the housing case is divided into two cavities, namely, an upper cavity and a lower cavity, by a referential base plate, the upper cavity is divided into a left chamber and a right chamber, one of the chambers is used for accommodation of the loading device, the other chamber is used for accommodation of the dyeing device, and the lower cavity is used for accommodation of the auxiliary device. The integrated machine provided in the invention enables loading of samples, centrifugation, preparation of smears and dyeing to be completed on one machine at a time; prepared liquid-based smears have stable quality, and cell structures on the smears are complete and uniformly disperse; the integrated machine is particularly suitable for large scale general investigation for cancer prevention and clinical diagnosis and screening in large special and general hospitals.
Description
Technical field
The present patent application relates to the integrated robot brain and the application in liquid based cytology detects thereof of a kind of liquid based cytology film-making and dyeing, belongs to the medical treatment detection device technical field.
Background technology
Exfoliative cytology is exactly a method of utilizing the normal cast-off cells of tissue to diagnose, liquid based cytology is the part of exfoliative cytology, be that the liquid of putting into a kind of intermediary by the reluctant exfoliative cytology sample of traditional approach is gone, to remove the interference component of influence diagnosis such as blood, mucus, reach the purpose that improves diagnosis.The liquid of intermediary is called as cell-preservation liquid, and it has functions such as the cellular morphology of maintenance, softening mucus, processing red blood cell.
The liquid based cytology inspection is to adopt liquid based thin-layer cell detection system to detect cell and carry out cytological classification diagnosis, it is advanced in the world at present a kind of cytolgical examination technology, compare with traditional Pap smear inspection, obviously improved the satisfaction and the abnormal cell recall rate of sample.
Liquid based cytology is mainly used in the dyeing of the human body cell sample being carried out cytology coloring agent smear, make standardized cytologic slide, be convenient to diagnosis, satisfy the requirement of clinical screening and family planning generaI investigation, for medical test and biological study, particularly significant aspect cytology and bacterial micro-organism check (generaI investigation of gynecological tumor generaI investigation, tulase, the inspection of ascites pleural fluid tumour cell etc.).But film-making and the artificial application of sample of dyeing, centrifugal, film-making and dyeing course very complicated are wasted time and energy, and are difficult in enormous quantities, high-level efficiency film-making dyeing.
Summary of the invention
The present patent application promptly be not high at the detecting instrument robotization that in the liquid based cytology detection range, exists at present, process is loaded down with trivial details, the shortcoming that wastes time and energy, designs and produces the device that a kind of full automatic collection application of sample, film-making and dyeing integration are realized.
Specifically, ask described a kind of Full Automatic Liquid basal cell's film-making dyeing integration machine among the present invention, it is characterized in that: described integral machine comprises casing and the sample adding device, dyeing apparatus and the servicing unit that are positioned at casing inside, wherein,
1, casing comprises main body, is positioned at the back shrouding at main body rear and is positioned at the face shield at main body top, is provided with the display operation screen above the main body front;
2, casing inside is divided into two chambers up and down, two chambers about the chamber on top is divided into again, one of them chamber housing sample adding device, another chamber housing dyeing apparatus, the chamber housing servicing unit of below by the benchmark base plate;
3, sample adding device comprises application of sample pot body, application of sample pot body lid is stamped on application of sample pot body top, be provided with the application of sample centrifugal pan at the application of sample pot nside, the below of application of sample centrifugal pan is provided with provides the application of sample of rotary power main drive gear, is provided with the application of sample feather key syringe needle that is used for application of sample above the side of application of sample centrifugal pan;
4, dyeing apparatus comprises the dyeing kettle body, dyeing kettle body upper cap has dyeing kettle body lid, be provided with the dyeing centrifugal pan at the dyeing pot nside, dyeing centrifugal pan below is provided with the dyeing of rotary power main drive gear is provided, and is provided with the dyeing feather key syringe needle of the liquid feeding that is used to dye above the side of dyeing centrifugal pan;
5, servicing unit comprises power control unit and liquid feed device, wherein, power control unit comprises mounting bracket and several film-making overflow dyeing machine air pumps that are positioned on the mounting bracket, film-making overflow dyeing machine air pump is connected respectively with the application of sample main drive gear with the dyeing main drive gear, is provided with the PCB circuit control panel of the described integral machine work of control in a side of mounting bracket; Liquid feed device comprises a plurality of fluid storage tanks and is positioned at the waste liquid recycling can of fluid storage tanks one side that fluid storage tanks is connected with film-making overflow dyeing machine air pump.
Described a kind of Full Automatic Liquid basal cell's film-making dyeing integration machine, it is characterized in that: the outside junction of described face shield and main body is provided with hinge.Realize the folding of face shield by hinge.
Described a kind of Full Automatic Liquid basal cell's film-making dyeing integration machine is characterized in that: the inboard of described face shield and main body is provided with and is used for the crank that face shield is opened the sealing support.
Described crank comprises two connecting rods with piston structure, and an end of connecting rod is connected with the inboard of face shield with the main body top respectively, and an other end is connected to each other.
Described a kind of Full Automatic Liquid basal cell's film-making dyeing integration machine is characterized in that: described main body covers front, bottom surface and two sides of casing.
Described a kind of Full Automatic Liquid basal cell's film-making dyeing integration machine, it is characterized in that: described integral machine also comprises roller, roller is positioned at four angles of bottom of shell.
Described roller comprises quiet universal wheel.
Described roller also comprises service brake.Be convenient to control the mobile of integral machine at any time and stop.
The application of the also claimed described Full Automatic Liquid basal cell's film-making dyeing integration machine of the present patent application in liquid based cytology detects.
The described a kind of Full Automatic Liquid basal cell's film-making dyeing integration machine of the present patent application has following advantage:
1, saves time and manpower, improved film-making dyeing efficient greatly;
2, system controlled by computer reduces personal error, has improved liquid base film-making dyeing quality, is convenient to the mass disposal sample, especially is convenient to the clinical diagnosis and the examination of extensive anti-cancer generaI investigation and large-scale training, general hospital;
3, realized that application of sample, centrifugal, film-making, dyeing once finishes at an instrument, the centre need not personnel and puts and keep, made liquid base smear steady quality, eucaryotic cell structure be complete, be evenly distributed, and especially being convenient to the clinical diagnosis and the examination of extensive anti-cancer generaI investigation and large-scale training, general hospital.
Description of drawings
Fig. 1 is the exterior perspective view of the embodiment of the invention;
Fig. 2 is the front view of the embodiment of the invention;
Fig. 3 is the A1-A1 cross-sectional view among Fig. 2;
Fig. 4 is the A2-A2 cross-sectional view among Fig. 2;
Fig. 5 is a B-B cross-sectional view among Fig. 2;
Fig. 6 is a T-T cross-sectional view among Fig. 2;
Wherein, 1 is that main body, 2 is the waste liquid recycling can for PCB circuit control panel, 95 for mounting bracket, 94 for film-making dyeing air pump, 93 for fluid storage tanks, 92 for benchmark base plate, 91 for dyeing feather key syringe needle, 8 for dyeing centrifugal pan, 75 for dyeing pot cover, 74 for dyeing kettle body, 73 for dyeing main drive gear, 72 for application of sample feather key syringe needle, 71 for application of sample centrifugal pan, 65 for application of sample pot cover, 64 for application of sample pot body, 63 for application of sample main drive gear, 62 for crank, 61 for hinge, 32 for display operation screen, 31 for roller, 5 for face shield, 4 for back shrouding, 3.
Embodiment
Below in conjunction with accompanying drawing; the described Full Automatic Liquid basal cell's film-making of the present patent application dyeing integration machine is described; purpose is better to understand the described technology contents of the present patent application for the public; rather than to the restriction of described technology contents; in fact; in the improvement of described integral machine being carried out with identical with the present patent application or approximate principle; comprise increase and decrease, replacement to corresponding construction; the change of the size of each several part, shape, quality is all within the present patent application technical scheme required for protection.
The described a kind of Full Automatic Liquid basal cell's film-making dyeing integration machine of the present patent application, comprise casing and the sample adding device, dyeing apparatus and the servicing unit that are positioned at casing inside, wherein, as illustrated in fig. 1 and 2, casing comprises main body 1, be positioned at the back shrouding 2 at main body 1 rear and be positioned at the face shield 3 at main body 1 top, above main body 1 front, be provided with display operation screen 5, roller 4 is positioned at four angles of bottom of shell, it can be quiet universal wheel, and service brake can be set, be convenient to moving and stopping of described integral machine; As Fig. 3, described, 3 and the outside junction of main body 1 be provided with hinge 31, by hinge, 31 realize the folding of face shields; The inboard of described face shield 3 and main body 1 is provided with and is used for the crank 32 that face shield is opened the sealing support, and described crank 32 comprises two connecting rods with piston structure, and an end of connecting rod is connected with the inboard of face shield with the main body top respectively, and an other end is connected to each other.
Casing inside is divided into two chambers up and down, two chambers about the chamber on top is divided into again, one of them chamber housing sample adding device, another chamber housing dyeing apparatus, the chamber housing servicing unit of below by benchmark base plate 8 (shown in Fig. 4).Wherein, shown in Fig. 3 and 5, sample adding device comprises application of sample pot body 62, application of sample pot body lid 63 is stamped on application of sample pot body 62 tops, be provided with application of sample centrifugal pan 64 in application of sample pot body 62 inside, the below of application of sample centrifugal pan 64 is provided with provides the application of sample of rotary power main drive gear 61, is provided with the application of sample feather key syringe needle 65 that is used for application of sample above the side of application of sample centrifugal pan 64; As shown in Figure 4 and Figure 5, dyeing apparatus comprises dyeing kettle body 72, dyeing kettle body 72 upper caps have dyeing kettle body lid 73, be provided with dyeing centrifugal pan 74 in dyeing kettle body 72 inside, dyeing centrifugal pan 74 belows are provided with the dyeing of rotary power main drive gear 71 are provided, and are provided with the dyeing feather key syringe needle 75 of the liquid feeding that is used to dye above the side of dyeing centrifugal pan 74; As shown in Figure 6, servicing unit comprises power control unit and liquid feed device, wherein, power control unit comprises mounting bracket 93 and several film-making overflow dyeing machine air pumps 92 that are positioned on the mounting bracket 93, film-making overflow dyeing machine air pump 92 is connected respectively with the application of sample main drive gear with the dyeing main drive gear, is provided with the PCB circuit control panel 94 of the described integral machine work of control in a side of mounting bracket 93; Liquid feed device comprises a plurality of fluid storage tanks 91 and is positioned at the waste liquid recycling can 95 of fluid storage tanks one side that fluid storage tanks is connected with film-making overflow dyeing machine air pump.
Described Full Automatic Liquid basal cell's film-making dyeing integration machine, realized that application of sample, centrifugal, film-making, dyeing once finishes at an instrument, the centre need not personnel and puts and keep, made liquid base smear steady quality, eucaryotic cell structure be complete, be evenly distributed, and especially being convenient to the clinical diagnosis and the examination of extensive anti-cancer generaI investigation and large-scale training, general hospital.
Claims (9)
1. Full Automatic Liquid basal cell film-making dyeing integration machine is characterized in that: described integral machine comprises casing and is positioned at sample adding device, dyeing apparatus and the servicing unit of casing inside, wherein,
1) casing comprises main body, is positioned at the back shrouding at main body rear and is positioned at the face shield at main body top, is provided with the display operation screen above the main body front;
2) casing inside is divided into two chambers up and down, two chambers about the chamber on top is divided into again, one of them chamber housing sample adding device, another chamber housing dyeing apparatus, the chamber housing servicing unit of below by the benchmark base plate;
3) sample adding device comprises application of sample pot body, application of sample pot body lid is stamped on application of sample pot body top, be provided with the application of sample centrifugal pan at the application of sample pot nside, the below of application of sample centrifugal pan is provided with provides the application of sample of rotary power main drive gear, is provided with the application of sample feather key syringe needle that is used for application of sample above the side of application of sample centrifugal pan;
4) dyeing apparatus comprises the dyeing kettle body, dyeing kettle body upper cap has dyeing kettle body lid, be provided with the dyeing centrifugal pan at the dyeing pot nside, dyeing centrifugal pan below is provided with the dyeing of rotary power main drive gear is provided, and is provided with the dyeing feather key syringe needle of the liquid feeding that is used to dye above the side of dyeing centrifugal pan;
5) servicing unit comprises power control unit and liquid feed device, wherein, power control unit comprises mounting bracket and several film-making overflow dyeing machine air pumps that are positioned on the mounting bracket, film-making overflow dyeing machine air pump is connected respectively with the application of sample main drive gear with the dyeing main drive gear, is provided with the PCB circuit control panel of the described integral machine work of control in a side of mounting bracket; Liquid feed device comprises a plurality of fluid storage tanks and is positioned at the waste liquid recycling can of fluid storage tanks one side that fluid storage tanks is connected with film-making overflow dyeing machine air pump.
2. a kind of Full Automatic Liquid basal cell's film-making dyeing integration machine according to claim 1, it is characterized in that: the outside junction of described face shield and main body is provided with hinge.
3. a kind of Full Automatic Liquid basal cell's film-making dyeing integration machine according to claim 1 is characterized in that: the inboard of described face shield and main body is provided with and is used for the crank that face shield is opened the sealing support.
4. a kind of Full Automatic Liquid basal cell's film-making dyeing integration machine according to claim 3, it is characterized in that: described crank comprises two connecting rods with piston structure, one end of connecting rod is connected with the inboard of face shield with the main body top respectively, and an other end is connected to each other.
5. a kind of Full Automatic Liquid basal cell's film-making dyeing integration machine according to claim 1 is characterized in that: described main body covers front, bottom surface and two sides of casing.
6. a kind of Full Automatic Liquid basal cell's film-making dyeing integration machine according to claim 1, it is characterized in that: described integral machine also comprises roller, roller is positioned at four angles of bottom of shell.
7. a kind of Full Automatic Liquid basal cell's film-making dyeing integration machine according to claim 6, it is characterized in that: described roller comprises quiet universal wheel.
8. a kind of Full Automatic Liquid basal cell's film-making dyeing integration machine according to claim 6, it is characterized in that: described roller also comprises service brake.
9. the application of the described a kind of Full Automatic Liquid basal cell's film-making dyeing integration machine of claim 1 in liquid based cytology detects.
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| CN2011102011083A CN102297794A (en) | 2011-07-18 | 2011-07-18 | Full automatic integrated liquid-based cytological smear making and dyeing machine and its application |
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| CN2011102011083A CN102297794A (en) | 2011-07-18 | 2011-07-18 | Full automatic integrated liquid-based cytological smear making and dyeing machine and its application |
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Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102735519A (en) * | 2012-06-19 | 2012-10-17 | 沈阳大学 | Automatic staining apparatus for biological tissue |
| CN103293034A (en) * | 2012-02-24 | 2013-09-11 | 奚金华 | Full-automatic pathological tissue slide-making system |
| CN105063942A (en) * | 2015-08-14 | 2015-11-18 | 湖州新嘉怡丝织印花有限公司 | Dye vat |
| CN105092329A (en) * | 2015-07-31 | 2015-11-25 | 曹春杰 | Medical test sample auxiliary processor |
| CN105890958A (en) * | 2014-11-24 | 2016-08-24 | 王素蓉 | Staining method |
| CN106289922A (en) * | 2016-08-31 | 2017-01-04 | 宁波华莱斯医疗器械有限公司 | A kind of liquid base cell sheet producing machine |
| CN108168986A (en) * | 2018-03-21 | 2018-06-15 | 深圳市鹏医疗仪器有限公司 | Full-automatic liquid-based cell sample manufacturing dyeing all-in-one machine and film-making colouring method |
| CN112326393A (en) * | 2020-11-30 | 2021-02-05 | 上海北昂医药科技股份有限公司 | Automatic cell sheet-making instrument |
| CN112504796A (en) * | 2020-12-04 | 2021-03-16 | 中国人民解放军陆军军医大学第二附属医院 | Integrated cell treatment device |
| CN113218730A (en) * | 2021-04-25 | 2021-08-06 | 南京江河华晟医学检验实验室有限公司 | Quality control and guarantee method for liquid-based membrane type cytology full-automatic dyeing |
| CN113515077A (en) * | 2021-04-23 | 2021-10-19 | 重庆德方信息技术有限公司 | System and method for monitoring human body cell staining process |
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2011
- 2011-07-18 CN CN2011102011083A patent/CN102297794A/en active Pending
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103293034A (en) * | 2012-02-24 | 2013-09-11 | 奚金华 | Full-automatic pathological tissue slide-making system |
| CN103293034B (en) * | 2012-02-24 | 2015-09-02 | 奚金华 | Full-automatic pathological tissue moviemaking system |
| CN102735519A (en) * | 2012-06-19 | 2012-10-17 | 沈阳大学 | Automatic staining apparatus for biological tissue |
| CN105890958A (en) * | 2014-11-24 | 2016-08-24 | 王素蓉 | Staining method |
| CN105092329B (en) * | 2015-07-31 | 2018-06-26 | 青岛市妇女儿童医院 | Medical test sample secondary processor |
| CN105092329A (en) * | 2015-07-31 | 2015-11-25 | 曹春杰 | Medical test sample auxiliary processor |
| CN105063942A (en) * | 2015-08-14 | 2015-11-18 | 湖州新嘉怡丝织印花有限公司 | Dye vat |
| CN106289922A (en) * | 2016-08-31 | 2017-01-04 | 宁波华莱斯医疗器械有限公司 | A kind of liquid base cell sheet producing machine |
| CN108168986A (en) * | 2018-03-21 | 2018-06-15 | 深圳市鹏医疗仪器有限公司 | Full-automatic liquid-based cell sample manufacturing dyeing all-in-one machine and film-making colouring method |
| CN112326393A (en) * | 2020-11-30 | 2021-02-05 | 上海北昂医药科技股份有限公司 | Automatic cell sheet-making instrument |
| CN112504796A (en) * | 2020-12-04 | 2021-03-16 | 中国人民解放军陆军军医大学第二附属医院 | Integrated cell treatment device |
| CN113515077A (en) * | 2021-04-23 | 2021-10-19 | 重庆德方信息技术有限公司 | System and method for monitoring human body cell staining process |
| CN113218730A (en) * | 2021-04-25 | 2021-08-06 | 南京江河华晟医学检验实验室有限公司 | Quality control and guarantee method for liquid-based membrane type cytology full-automatic dyeing |
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Application publication date: 20111228 |