CN201225970Y - Cell tablet dyeing machine - Google Patents
Cell tablet dyeing machine Download PDFInfo
- Publication number
- CN201225970Y CN201225970Y CNU2008200470948U CN200820047094U CN201225970Y CN 201225970 Y CN201225970 Y CN 201225970Y CN U2008200470948 U CNU2008200470948 U CN U2008200470948U CN 200820047094 U CN200820047094 U CN 200820047094U CN 201225970 Y CN201225970 Y CN 201225970Y
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- slide
- making
- film
- installing plate
- dyeing
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- Expired - Fee Related
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Abstract
The utility model discloses a cell preparation dyeing machine and aims at providing a cell preparation dyeing machine which has the advantages of high automatization degree and high preparation efficiency and can simultaneously carry out preparation and dyeing. The cell preparation dyeing machine includes a shell (1), a platform frame (2), a centrifugal device (3), a transferring device (4) and a preparation dyeing device (5); the centrifugal device (3) and the preparation dyeing device (5) are arranged on the platform frame (2); the transferring device (4) is arranged between the centrifugal device (3) and the preparation dyeing device (5) and is arranged on the crossbeam of the platform frame (2) in a sliding way; the cell preparation dyeing machine is automatically and integrally operated during the whole process from centrifugal sampling to preparation and dyeing and can be broadly applied to the field of medical biology.
Description
Technical field
The utility model relates to a kind of cell film-making overflow dyeing machine.
Background technology
In medical biological study occasion, often need the pair cell sample to carry out film-making, dyeing.Nowadays adopt the automatic film-making of cell smear machine to obtain application more and more widely.Existing cell smear machine is divided into two kinds of automatic film-making and manual film-makings according to the working method difference, and its film-making process is as follows:
Automatically film-making: 1, instrument is delivered to the high precision filtering membrane tube in the specimen fluids bottle automatically, by the dispersed with stirring cell; 2, system vacuumizes automatic collecting cell; 3, after the collection cell finished, system extracted raffinate automatically out; 4, after raffinate extracted and finishes, system's control sampling mechanical arm moved, and makes the high precision filtering membrane tube contact with the slide level, and by malleation cell is automatically transferred on the slide; 5, system moves back automatically and unloads or move back by hand and unload high precision filtering membrane tube, system reset; 6, hand dyeing or on automatic slide stainer, dye.
Manual film-making: 1, centrifugal to specimen fluids by hydro-extractor, remove supernatant; 2, in sediment, add an amount of cell and handle base fluid, mixing sediment; 3, obtained cell suspension is poured on the microslide in right amount, dries or dries (perhaps by secondary centrifuging cell being got rid of to microslide).4, hand dyeing or on automatic slide stainer, dye.
There are some incomplete places in the process that prior art is made Cell sheet glass:
Can only carry out simple film-making, can not dye simultaneously, can not effectively alleviate medical personnel's workload;
Automatically film-making is had relatively high expectations to specimen sampling, is prone to the more and situation of influence diagnosis of mucus in the slice, thin piece, and once can only the requirement that can not satisfy the large hospital workload of film-making;
Manual film-making slice, thin piece is prone to inflammatory cell protective epithelium cell and influences the situation of diagnosis, need manual operations though film-making efficient is higher, operating personnel's experience is had relatively high expectations, and owing to adopt common slide phenomenon acellular or that cell concentration is few often to occur.
The utility model content
Technical problem to be solved in the utility model is to overcome the deficiencies in the prior art, the cell film-making overflow dyeing machine that provide a kind of automaticity height, film-making efficient height, can carry out film-making and dyeing simultaneously.
The technical scheme that the utility model adopted is: the utility model comprises casing, stand, centrifugal device, transfer device and film-making dyeing apparatus, described centrifugal device and film-making dyeing apparatus are loaded on the described stand, and described transfer device is arranged between centrifugal device and the film-making dyeing apparatus and is slidingly mounted on the crossbeam on described stand top.
Described centrifugal device comprises centrifugal bottle, cup and rotating disk platform, and described rotating disk platform rotates and is arranged on the stand, and described cup is evenly distributed on the circumference of rotating disk platform.
Described centrifugal bottle is arranged in the circular hole inner chamber of cup, and its bottom has the conical flask bottom structure.
Described transfer device comprises horizontal installing plate I, column, described horizontal installing plate I is fixedlyed connected with described column, described horizontal installing plate I is provided with slide rail I and two ends are equipped with synchronous pulley I, synchronous pulley II, be connected with synchronous band I between described synchronous pulley I and the described synchronous pulley II, described belt wheel I place is provided with motor I, described slide rail I is provided with slide device and matches with it, and this slide device can slidably reciprocate along described slide rail I.
Described slide device comprises slide plate I, upright installing plate, described slide plate I is fixedlyed connected with upright installing plate, described upright installing plate is provided with slide rail II and two ends are equipped with synchronous pulley III and synchronous pulley IV, be connected with synchronous band II between the described synchronous pulley, described belt wheel IV place is combined with motor II, described slide rail II is provided with lifting table, this lifting table is fixedlyed connected with described synchronous band II and is slided up and down along described slide rail II and moves, described lifting table is equipped with rifle and chews loop bar, and this rifle is chewed the loop bar tip engages has rifle to chew.
Described film-making dyeing apparatus comprises circular slide rotating disk, slide, settling vat and dyeing arm, described slide rotating disk rotation is installed on the stand, described slide is evenly distributed on the circumference of described slide rotating disk, described settling vat is arranged on the middle position of slide, one end of described dyeing arm is equipped with needle tubing, and the other end is fixed on the slide bar of vertical direction; Also fixedly install end installing plate below stand, motor I vertically is installed on installing plate of the described end and is horizontally installed with motor II, described motor I makes slide bar rotate along the axle center by meshed transmission gear; Also be provided with guide pole and slide block on the installing plate of the described end, described motor II drives described slide block by synchronous band and moves up and down, and on described guide pole the relative slip fixedly connected with slide bar of described slide block.
On the stand at position between described centrifugal device and the film-making dyeing apparatus, be provided with rifle chew the dish and unload rifle and chew box.
The beneficial effects of the utility model are: the utility model has realized that transferring to the cell film-making from sampling finishes automatically with dyeing whole process is integrated, effectively alleviates medical personnel's workload; And film-making and dyeing carries out simultaneously, but the demand of large hospital workload is satisfied in once many of film-makings; The utility model is with respect to manual film-making, and operating personnel's experience is required and can not limit.
Description of drawings
Fig. 1 is a structural representation of the present utility model;
Fig. 2 is a vertical view of the present utility model;
Fig. 3 is the structural representation of centrifugal device described in the utility model;
Fig. 4 is the structure cut-open view of centrifugal bottle described in the utility model;
Fig. 5 is the front view of transfer device described in the utility model;
Fig. 6 is the left view of transfer device described in the utility model;
Fig. 7 is the structural representation of film-making dyeing apparatus described in the utility model;
Fig. 8 is the vertical view of film-making dyeing apparatus described in the utility model.
Embodiment
Principle of work of the present utility model is as follows:
After opening instrument power source, system automatically resets.Operating personnel contrast the numbering check mark and install consumptive material (after being slide 502 and settling vat 503 (being installed on the described slide rotating disk 501), centrifugal bottle 301 (being placed on the described cup 302), pass Long Position lid, press the " RUN " button of control panel, instrument is finished film-making dyeing work by following working routine automatically:
1: system start-up centrifugal device 3 behind the centrifugal 10min of 2000rpm, stops centrifugal and calibrating position automatically;
2: start discharge opeing mechanical arm 8, stretch in the centrifugal bottle 301, supernatant is extracted, behind the residue sediment, the pipeline of playback and flushing discharge opeing mechanical arm 8;
3: start transfer device 4, rifle chew obtain rifle on the dish 6 and chew 417 after, move and stretch into centrifugal bottle 301, add the 2ml cell and handle base fluid, mixing cell; Draw the 800ul cell suspension again, be transferred in the settling vat 503 that is installed in corresponding numbering on the slide rotating disk 501, transfer device 4 moves back to unload and playbacks after rifle chews 417;
4: natural subsidence 5min;
5: start film-making dyeing apparatus 5, the needle tubing of dyeing arm 504 is stretched in the settling vat, get rid of waste liquid;
6: by different pipeline on the dyeing arm 504, inject different operating liquid, get rid of waste liquid after each step is finished, finish dyeing work.Idiographic flow is (an improved Papanicolaou): fix → entry → haematoxylin dyeing → return indigo plant → dehydration → improvement EA50 dyeing → dehydration;
8: system automatically resets, waits for next instruction after finishing film-making dyeing.
Claims (7)
1, a kind of cell film-making overflow dyeing machine, comprise casing (1), stand (2), centrifugal device (3), transfer device (4) and film-making dyeing apparatus (5), it is characterized in that: described centrifugal device (3) and film-making dyeing apparatus (5) are loaded on the described stand (2), and described transfer device (4) is arranged between centrifugal device (3) and the film-making dyeing apparatus (5) and is slidingly mounted on the crossbeam on described stand (2) top.
2, cell film-making overflow dyeing machine according to claim 1, it is characterized in that: described centrifugal device (3) comprises centrifugal bottle (301), cup (302) and rotating disk platform (303), described rotating disk platform (303) rotates and is arranged on the stand (2), and described cup (302) is evenly distributed on the circumference of rotating disk platform (303).
3, cell film-making overflow dyeing machine according to claim 2 is characterized in that: described centrifugal bottle (301) is arranged in the circular hole inner chamber of cup (302), and its bottom has (304) structure at the bottom of the conical flask.
4, cell film-making overflow dyeing machine according to claim 1, it is characterized in that: described transfer device (4) comprises horizontal installing plate I (401), column (402), described horizontal installing plate I (401) is fixedlyed connected with described column (402), described horizontal installing plate I (402) is provided with slide rail I (403) and two ends are equipped with synchronous pulley I (404), synchronous pulley II (405), be connected with synchronous band I (406) between described synchronous pulley I (404) and the described synchronous pulley II (405), described belt wheel I (404) locates to be provided with motor I (407), described slide rail I (403) is provided with slide device and matches with it, and this slide device can slidably reciprocate along described slide rail I (403).
5, cell film-making overflow dyeing machine according to claim 4, it is characterized in that: described slide device comprises slide plate I (408), upright installing plate (409), described slide plate I (408) is fixedlyed connected with upright installing plate (409), described upright installing plate (409) is provided with slide rail II (410) and two ends are equipped with synchronous pulley III (411) and synchronous pulley IV (412), be connected with synchronous band II (413) between the described synchronous pulley, described belt wheel IV (412) locates to be combined with motor II (414), described slide rail II (410) is provided with lifting table (415), this lifting table (415) is fixedlyed connected with described synchronous band II (413) and along described slide rail II (410) motion that slides up and down, described lifting table (415) is equipped with rifle and chews loop bar (416), and this rifle is chewed loop bar (416) tip engages has rifle to chew (417).
6, cell film-making overflow dyeing machine according to claim 1, it is characterized in that: described film-making dyeing apparatus (5) comprises circular slide rotating disk (501), slide (502), settling vat (503) and dyeing arm (504), described slide rotating disk (501) rotation is installed on the stand (2), described slide (502) is evenly distributed on the circumference of described slide rotating disk (501), described settling vat (503) is arranged on the middle position of slide (502), one end of described dyeing arm (504) is equipped with needle tubing (505), and the other end is fixed on the slide bar (506) of vertical direction; Also fixedly install end installing plate (507) in stand (2) below, motor I (508) vertically is installed on installing plate of the described end (507) and is horizontally installed with motor II (509), described motor I (508) makes slide bar (506) rotate along the axle center by meshed transmission gear; Also be provided with guide pole (510) and slide block (511) on the installing plate of the described end (507), described motor II (509) moves up and down by being with (512) to drive described slide block (511) synchronously, described slide block (511) and on described guide pole (510) relative slip fixedly connected with slide bar (506).
7, according to each described cell film-making overflow dyeing machine of claim 1 to 6, it is characterized in that: on the stand (2) at position between described centrifugal device (3) and the film-making dyeing apparatus (5), be provided with rifle and chew dish (6) and unload rifle and chew box (7).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2008200470948U CN201225970Y (en) | 2008-04-29 | 2008-04-29 | Cell tablet dyeing machine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2008200470948U CN201225970Y (en) | 2008-04-29 | 2008-04-29 | Cell tablet dyeing machine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201225970Y true CN201225970Y (en) | 2009-04-22 |
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ID=40598865
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNU2008200470948U Expired - Fee Related CN201225970Y (en) | 2008-04-29 | 2008-04-29 | Cell tablet dyeing machine |
Country Status (1)
| Country | Link |
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| CN (1) | CN201225970Y (en) |
Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102053031A (en) * | 2011-01-13 | 2011-05-11 | 上海斯而杰医疗器械技术有限公司 | Automatic blood film making and dyeing instrument |
| CN102323134A (en) * | 2011-09-05 | 2012-01-18 | 上海皓信生物科技有限公司 | Automatic gram staining and centrifugation system for bacterium and cells |
| CN102607914A (en) * | 2012-03-08 | 2012-07-25 | 张晓东 | Turnover cell tabletting device |
| CN102768142A (en) * | 2012-07-19 | 2012-11-07 | 广州市达诚医疗技术有限公司 | Dyeing device |
| CN103018088A (en) * | 2013-01-10 | 2013-04-03 | 武汉市康创科技有限公司 | Fully-automatic liquid-based centrifugation and tableting machine |
| CN103398890A (en) * | 2013-08-22 | 2013-11-20 | 麦克奥迪（厦门）医疗诊断系统有限公司 | Liquid-based cell sheet producing system and liquid-based cell sheet producing method |
| CN103543058A (en) * | 2012-07-10 | 2014-01-29 | 天津百利鑫生物科技有限公司 | Liquid injection and suction method for cell slide-making dyeing machine and device thereof |
| CN103604679A (en) * | 2013-11-25 | 2014-02-26 | 武汉友芝友医疗科技有限公司 | Capture instrument for circulating tumor cells and method for capturing and staining by using capture instrument |
| CN103884564A (en) * | 2014-04-02 | 2014-06-25 | 深圳市达科为医疗科技有限公司 | Tissue slice dyeing machine with two mechanical arms |
| WO2017071340A1 (en) * | 2015-10-30 | 2017-05-04 | 广州鸿琪光学仪器科技有限公司 | Suction nozzle collection device, and staining machine |
| CN108452958A (en) * | 2018-01-25 | 2018-08-28 | 陈柯 | A kind of Bioexperiment equipment |
| CN110631879A (en) * | 2019-10-28 | 2019-12-31 | 宁波美生医疗器材有限公司 | Medical equipment for automatic liquid-based cell flaking and dyeing |
| WO2020258155A1 (en) * | 2019-06-27 | 2020-12-30 | 深圳迈瑞生物医疗电子股份有限公司 | Slide maker and control method therefor |
| CN112179738A (en) * | 2020-09-30 | 2021-01-05 | 易普森生物科技(深圳)有限公司 | Novel cell pelleter |
| EP4206641A4 (en) * | 2020-10-09 | 2024-03-13 | Jiaxing Jingzhu Biotechnology Co Ltd | Integrated device for constant-temperature fully-automatic cell slide preparation, and slide preparation method |
| EP4206642A4 (en) * | 2020-10-09 | 2024-03-13 | Jiaxing Jingzhu Biotechnology Co Ltd | Fully automated method for production of exfoliated cells |
-
2008
- 2008-04-29 CN CNU2008200470948U patent/CN201225970Y/en not_active Expired - Fee Related
Cited By (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102053031A (en) * | 2011-01-13 | 2011-05-11 | 上海斯而杰医疗器械技术有限公司 | Automatic blood film making and dyeing instrument |
| CN102053031B (en) * | 2011-01-13 | 2014-12-10 | 上海斯而杰医疗器械技术有限公司 | Automatic blood film making and dyeing instrument |
| CN102323134A (en) * | 2011-09-05 | 2012-01-18 | 上海皓信生物科技有限公司 | Automatic gram staining and centrifugation system for bacterium and cells |
| CN102323134B (en) * | 2011-09-05 | 2013-03-13 | 上海皓信生物科技有限公司 | Automatic gram staining and centrifugation system for bacterium and cells |
| CN102607914A (en) * | 2012-03-08 | 2012-07-25 | 张晓东 | Turnover cell tabletting device |
| CN102607914B (en) * | 2012-03-08 | 2015-06-17 | 张晓东 | Turnover cell tabletting device |
| CN103543058A (en) * | 2012-07-10 | 2014-01-29 | 天津百利鑫生物科技有限公司 | Liquid injection and suction method for cell slide-making dyeing machine and device thereof |
| CN103543058B (en) * | 2012-07-10 | 2016-06-15 | 天津百利鑫生物科技有限公司 | For fluid injection imbibition method and the device thereof of cell preparation staining machine |
| CN102768142A (en) * | 2012-07-19 | 2012-11-07 | 广州市达诚医疗技术有限公司 | Dyeing device |
| CN102768142B (en) * | 2012-07-19 | 2014-09-10 | 广州市达诚医疗技术有限公司 | Dyeing device |
| CN103018088B (en) * | 2013-01-10 | 2015-04-22 | 武汉市康创科技有限公司 | Fully-automatic liquid-based centrifugation and tableting machine |
| CN103018088A (en) * | 2013-01-10 | 2013-04-03 | 武汉市康创科技有限公司 | Fully-automatic liquid-based centrifugation and tableting machine |
| CN103398890A (en) * | 2013-08-22 | 2013-11-20 | 麦克奥迪（厦门）医疗诊断系统有限公司 | Liquid-based cell sheet producing system and liquid-based cell sheet producing method |
| CN103398890B (en) * | 2013-08-22 | 2015-11-11 | 麦克奥迪（厦门）医疗诊断系统有限公司 | A kind of liquid-based cell sample manufacturing system and flaking method thereof |
| CN103604679B (en) * | 2013-11-25 | 2015-12-30 | 武汉友芝友医疗科技有限公司 | A kind of circulating tumor cell is caught instrument and catches colouring method |
| CN103604679A (en) * | 2013-11-25 | 2014-02-26 | 武汉友芝友医疗科技有限公司 | Capture instrument for circulating tumor cells and method for capturing and staining by using capture instrument |
| CN103884564A (en) * | 2014-04-02 | 2014-06-25 | 深圳市达科为医疗科技有限公司 | Tissue slice dyeing machine with two mechanical arms |
| CN103884564B (en) * | 2014-04-02 | 2016-08-24 | 达科为（深圳）医疗设备有限公司 | A kind of double mechanical arms slide stainer |
| WO2017071340A1 (en) * | 2015-10-30 | 2017-05-04 | 广州鸿琪光学仪器科技有限公司 | Suction nozzle collection device, and staining machine |
| CN108452958A (en) * | 2018-01-25 | 2018-08-28 | 陈柯 | A kind of Bioexperiment equipment |
| CN108452958B (en) * | 2018-01-25 | 2019-01-08 | 平湖市华晟机械有限公司 | A kind of Bioexperiment equipment |
| WO2020258155A1 (en) * | 2019-06-27 | 2020-12-30 | 深圳迈瑞生物医疗电子股份有限公司 | Slide maker and control method therefor |
| CN110631879A (en) * | 2019-10-28 | 2019-12-31 | 宁波美生医疗器材有限公司 | Medical equipment for automatic liquid-based cell flaking and dyeing |
| CN112179738A (en) * | 2020-09-30 | 2021-01-05 | 易普森生物科技(深圳)有限公司 | Novel cell pelleter |
| CN112179738B (en) * | 2020-09-30 | 2021-07-13 | 易普森生物科技(深圳)有限公司 | Novel cell pelleter |
| EP4206641A4 (en) * | 2020-10-09 | 2024-03-13 | Jiaxing Jingzhu Biotechnology Co Ltd | Integrated device for constant-temperature fully-automatic cell slide preparation, and slide preparation method |
| EP4206642A4 (en) * | 2020-10-09 | 2024-03-13 | Jiaxing Jingzhu Biotechnology Co Ltd | Fully automated method for production of exfoliated cells |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20090422 Termination date: 20120429 |