CN103239695A - Preparation method of traditional Chinese medicine for treating alcohol-related acute glomerulonephritis - Google Patents

Abstract

The invention provides a preparation method of a traditional Chinese medicine for treating acute glomerulonephritis, and belongs to the technical field of the preparation methods of the traditional Chinese medicines, solving the problem that penicillin is always used for treating the alcohol-related acute glomerulonephritis and but easily causes allergic reaction, in particular anaphylactic shock. According to the technical scheme, the preparation method comprises the following steps of: soaking twenty eight traditional Chinese medicines including hemerocallis miner, semen sojae germinatum, helicteres angustifolia, curly bristlethistle herb, lawn pennywort herb, horsetail, eleusine indica, burdock, cimicifugae foetidae, ginger, radix angelicae, common bluebeard herb, cymbopogon distans, artemisia japonica, willow branch, tamarix chinensis, hawthorn, rice sprout, iris tectorum, carrot, endothelium corneum gigeriae galli, buckwheat, medicated leaven, semen raphani, papaya, quince, kudzuvine root and liquorice in water; and decocting with soft fire, thus obtaining liquid medicine which is the traditional Chinese medicine for treating the alcohol-related acute glomerulonephritis. The preparation method has the advantages that the preparation is simple, the prepared liquid traditional Chinese medicine has little toxic and side effects, the course of treatment is short, and the recovery rate is high; and monarch medicines, ministerial medicines, adjuvant medicines and conductant medicines are matched properly.

Description

A kind of Chinese medicinal preparation method for the treatment of excessive drinking type acute glomerulonephritis

Technical field

The present invention relates to the Chinese medicinal preparation method technical field, is a kind of Chinese medicinal preparation method for the treatment of excessive drinking type acute glomerulonephritis more specifically.

Background technology

The type for the treatment of excessive drinking at present acute glomerulonephritis, the general employing: 1, penicillin: allergy easily takes place in this product, anaphylactic shock (the most dangerous anaphylactic shock particularly, can occur in and do tuerculoderma at that time, only a few can occur in the continuous use process, the Delayed Hypersensitivity shock), as untimely rescue, can critical life, thus all to improve protection before, during and after the medication, so as to avoid an accident.Attention: before the application, must ask to have or not anaphylactic disease clearly, with having or not allergy such as erythra, heating to occur behind the penicillin, must do the penicillin skin test earlier.2, captopril: important side effect is Toxicity of Kidney and granulocytopenia, is erythra, dysgeusia and cough secondly.Heavy dose can cause hemodynamic change, symptomatic hypotension etc.3, bendazol: headache, hyperhidrosis, heating sense are arranged.4, reserpine: nasal obstruction, gastric acid secretion increase, times of defecation increases and aroused in interest slack-off etc., even apathetic expression can appear in long-term extensive application, drowsiness, spirit depressing causes extrapyramidal symptoms, the performance muscular tremor.1. to activeness Peptic Ulcers and dysthymia person's forbidding; 2. reserpine can enter fetal tissue by Placenta Hominis, if the antenatal application of anemia of pregnant woman can cause neonate nasal obstruction, respiratory tract obstruction, should try one's best need not.5, carbenicillin: various types of allergy can occur.May cause neural poison reaction, pulmonary edema after heavy dose of administration, may occur the transience transaminase during the medication and raise and granulocytopenia.

Summary of the invention

For overcoming above-mentioned shortcoming, the objective of the invention is to invent a kind of Chinese medicinal preparation method for the treatment of excessive drinking type acute glomerulonephritis.Acute glomerulonephritis is called for short acute nephritis, is one group of common glomerule illness.Onset is anxious, is its Clinical symptoms with hematuria, oliguria, albuminuria, edema and hypertension etc.Acute nephritis can be because of due to the Different types of etiopathogenises, and wherein modal is post-streptococcal infection nephritis, and other causes of disease still have antibacterial (as staphylococcus), virus (as hepatitis B virus), protozoon (as plasmodium) etc.Primary disease belongs to " edema due to wind pathogen ", the category of " YANG edema " and " hematuria " in the Chinese medicine " edema ".

Etiology and pathogenesis:Acute glomerulonephritis is main clinical manifestation with hematuria, edema,proteinuria,hypertension.Human liquid's metabolism relies on the logical of lung qi to transfer, the transferring of temper, and opening of kidney qi is entire, thereby makes three warmers bring into play the duty that it is certainly shown disrespect on.Ailment said due to cold or exposure, water are wet in order to experience for the primary disease cause of disease, noxious dampness, damp and hot heresy, invasion and attack flesh table, and internal injury is in lung, impairment of dispersing and descending function of the lung; Or in be attributed to spleen, spleen loses fortuneization; Under injure kidney, kidney loses folding, disturbance in water passage then, and be edema.In the acute nephritis edema stage, the main diseases position is at lung, spleen, based on inhibited pulmonary QI.If hematuria is obvious, how by the damp-heat accumulation bladder, injury of blood collaterals by heat is due to venation is impaired.If the intenseness of heat wind symptom, disturb sun clearly on the wind-fire, dizziness headache then appears, even the evil cards of violating conscience such as convulsions, coma.Spleen-QI failing to rise up, deficiency of kidney-QI, smart closing admittedly, albuminuria then appears in the separating clear and excreting turbid dereliction of duty.So the sick position of primary disease is dirty at lung, spleen, kidney three, syndrome develop be from table and in, reach the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels by the part of the body cavity above the diaphragm housing the heart and lungs, middle Jiao, develop to simulataneous insufficiency and excessive from real.Since long-term excessive drinking, the frequent fever that wets more, and damp-heat accumulation forms this disease.

Clinical manifestation:Long-term excessive drinking.Onset is more anxious, and state of an illness weight does not wait.Most of patients has clear and definite streptococcal infection history, as upper respiratory tract infection, pharyngitis, tonsillitis and skin infection etc.Sudden onset, first symptom mostly is edema and hematuria.1, edema: the lighter only plays blepharoedema morning, and complexion is paler, is " nephritis face ".Weight person prolongs and whole body, and finger pressure skin can not have significant depressions, and body weight also increases thereupon.2, hypertension: see 80% case, mostly be light moderate hypertension, diastolic pressure is less than 14kpa.The hypertension of acute nephritis mostly is a property crossed, and the generation reason is mainly water, sodium retention makes due to the blood volume expansion.3, urine is unusual: 1. oliguria: the most of patients onset has oliguria often, as every day the urine amount be less than 500ml person, slight azotemia can appear.2. hematuria: see all acute nephritis patients, can be gross hematuria, or muddy coffee-like, general persistence is not long, namely transfers microscopic hematuria to.3. albuminuria: most of patients all has 4. whole body performance of albuminuria in various degree: tired, lumbago, anorexia, feel sick, vomiting, the person of being in a bad way can have headache, dizziness, drowsiness, blurred vision etc.Body of the tongue is light red, greasy fur, slippery and rapid pulse.

Its technical scheme is:Get Herba Solidaginis 6 weight portions, Semen Glycine Germinatum 3 weight portions, Radix Helicteris 9 weight portions, Herba Cardui Crispi 3 weight portions, Herba Hydrocotyles 6 weight portions, Herba Equiseti Hiemalis's 6 weight portions, Herba Eleusines Indicae 9 weight portions, Fructus Arctii 6 weight portions, Rhizoma Cimicifugae 3 weight portions, Rhizoma Zingiberis Recens 9 weight portions, the Radix Angelicae Dahuricae 9 weight portions, Herba Caryopteridis Incanae 3 weight portions, Herba Cymbopogonis 6 weight portions, Herba Artemisiae Japonicae 3 weight portions, Ramulus Salicis Babylonicae 6 weight portions, Ramulus et Folium Tamaricis 3 weight portions, Fructus Crataegi 9 weight portions, Fructus Setariae Germinatus 9 weight portions, Rhizoma Iridis Tectori 1 weight portion, Radix Dauci Sativae 9 weight portions, Endothelium Corneum Gigeriae Galli 6 weight portions, Semen Fagopyri Esculenti 9 weight portions, Massa Medicata Fermentata 6 weight portions, Semen Raphani 6 weight portions, Fructus Caricae 9 weight portion Fructus cydoniae oblongae 6 weight portions, Radix Puerariae 3 weight portions and Radix Glycyrrhizae 9 weight portions, above 28 flavor Chinese medicines are put into 1800 ml waters, soaked 35 minutes, slow fire is fried 30 minutes then, boil medicine altogether 390 milliliters of liquid of filter and remove residue, fried medicinal liquid is the Chinese medicine for the treatment of excessive drinking type acute glomerulonephritis.

The advantage of this invention is:We's 28 flavor Chinese medicines all can have been bought in pharmacy, make simply, and the herb liquid toxic and side effects of making is little, short treating period, cure rate height.Monarch, just right.When using Chinese medicine, untoward reaction, anaphylaxis and the toxic reaction of having avoided Western medicine to cause.Herba Solidaginis, Semen Glycine Germinatum, Radix Helicteris, Herba Cardui Crispi, Herba Hydrocotyles, Herba Equiseti Hiemalis, Herba Eleusines Indicae, Fructus Arctii, Rhizoma Cimicifugae, Rhizoma Zingiberis Recens, the Radix Angelicae Dahuricae, Herba Caryopteridis Incanae, Herba Cymbopogonis, Herba Artemisiae Japonicae, Ramulus Salicis Babylonicae, Ramulus et Folium Tamaricis, more than 16 the flavor medical instruments wind and heat dispersing is arranged, heat-clearing and toxic substances removing, the dampness removing jaundice eliminating, cool the blood dissipate blood stasis, cooling blood for hemostasis, warming middle-JIAO to arrest vomiting, the effect that the painful abdominal mass that disappears is relieved the effect of alcohol.In the process for the treatment of excessive drinking type acute glomerulonephritis, play main therapeutical effect, so be monarch drug.Fructus Crataegi, Fructus Setariae Germinatus, Rhizoma Iridis Tectori, Radix Dauci Sativae, Endothelium Corneum Gigeriae Galli, Semen Fagopyri Esculenti, Massa Medicata Fermentata, Semen Raphani, Fructus Caricae, Fructus cydoniae oblongae, more than 10 flavor medical instruments the effect of promoting digestion and removing stagnation, circulation of qi promoting dissipating blood stasis, relieving dyspepsia, alleviating distention in middle-JIAO spleen invigorating, invigorating the spleen and regulating the stomach, appetizing removing food stagnancy, pain relieving is arranged.In the process for the treatment of excessive drinking type acute glomerulonephritis, can assist principal agent performance therapeutical effect, so be ministerial drug.Radix Puerariae: sweet, hot, flat, nontoxic.Go into stomach, spleen, lung, bladder four warps.Expelling pathogenic factors from muscles is delivered, and relieving restlessness is quenched the thirst, heat-clearing and toxic substances removing.The all medicines of the energy rate focus of going directly is so be adjuvant drug.Radix Glycyrrhizae: sweet, flat.Go into 12 warps.The spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.Can entangle the bias of all medicines, can alleviate the toxicity of all medicines again, so be messenger drug.Herba Solidaginis, Semen Glycine Germinatum, Radix Helicteris, Herba Cardui Crispi, Herba Hydrocotyles, Herba Equiseti Hiemalis, Herba Eleusines Indicae, Fructus Arctii, Rhizoma Cimicifugae, Rhizoma Zingiberis Recens, the Radix Angelicae Dahuricae, Herba Caryopteridis Incanae, Herba Cymbopogonis, Herba Artemisiae Japonicae, Ramulus Salicis Babylonicae, Ramulus et Folium Tamaricis, Fructus Crataegi, Fructus Setariae Germinatus, Rhizoma Iridis Tectori, Radix Dauci Sativae, Endothelium Corneum Gigeriae Galli, Semen Fagopyri Esculenti, Massa Medicata Fermentata, Semen Raphani, Fructus Caricae, Fructus cydoniae oblongae, Radix Puerariae, Radix Glycyrrhizae, more than 28 the flavor medical instruments wind and heat dispersing is arranged, heat-clearing and toxic substances removing, the dampness removing jaundice eliminating, cool the blood dissipate blood stasis, warming middle-JIAO to arrest vomiting, the painful abdominal mass that disappears is relieved the effect of alcohol, the effect of promoting digestion and removing stagnation, circulation of qi promoting dissipating blood stasis, alleviating distention in middle-JIAO spleen invigorating, invigorating the spleen and regulating the stomach, pain relieving.Monarch, compatibility is proper, is the optimum formula for the treatment of excessive drinking type acute glomerulonephritis.Herba Solidaginis: hot, bitter, cold.Go into liver, gallbladder two warps.Wind and heat dispersing, treating SHAO YANG disease by mediation, relieving cough and resolving phlegm, heat-clearing and toxic substances removing, dampness removing jaundice eliminating.Semen Glycine Germinatum: sweet, flat.Go into the stomach warp.Clearing away heat-damp and promoting diuresis, promoting blood circulation is controlled long-pending heat, blood stasis amenorrhea in the stomach.Radix Helicteris: hot, little hardship, cold.Go into the heart, lung, large intestine three warps.The heat clearing away of inducing sweat, removing toxic substances and promoting subsidence of swelling, expelling wind and removing dampness.Herba Cardui Crispi: bitter, hot, cooler.Go into lung, bladder, liver three warps.Expelling wind and clearing away heat, cool the blood dissipate blood stasis, removing toxic substances and promoting subsidence of swelling.Herba Hydrocotyles: bitter, hot, cold.Go into liver, spleen, lung three warps.Expelling wind and clearing away heat, removing toxic substances and promoting subsidence of swelling, promoting urination to remove dampness, relieving cough and resolving phlegm, bowel relieving dysentery relieving.Herba Equiseti Hiemalis: sweet, bitter, flat.Go into lung, liver, gallbladder three warps.Wind and heat dispersing, improving acuity of vision and removing nebula, cooling blood for hemostasis.Herba Eleusines Indicae: sweet, cold.Go into liver, stomach two warps.Clearing away summer-heat, clearing away heat-damp and promoting diuresis.Fructus Arctii: hot, bitter, cold.Go into lung, stomach two warps.Dispelling wind and heat pathogens, detoxifcation, rash, detoxifcation, sore-throat relieving, diffusing swollen.Rhizoma Cimicifugae: hot, sweet, be slightly cold.Go into spleen, stomach, lung, large intestine four warps.Deliver rash, heat-clearing and toxic substances removing, ascending up spleen-Qi and Yang.Rhizoma Zingiberis Recens: suffering, temperature.Go into lung, stomach, spleen three warps.Relieving the exterior syndrome by diaphoresis, warming middle-JIAO to arrest vomiting, warming the lung to relieve cough, diuresis and phlem dispersing, dispelling cold and removing dampness is separated the Rhizoma Pinelliae, Rhizoma Arisaematis and fish Eriocheir sinensis, birds and beasts meat poison, stomach invigorating increases food.The Radix Angelicae Dahuricae: suffering, temperature.Go into lung, spleen, stomach three warps.Induce sweat dispeiling pathogenic wind and removing dampness, pain relieving, detumescence and apocenosis, dispelling wind for relieving itching.Herba Caryopteridis Incanae: hot, little hardship, flat.Go into lung, spleen, kidney three warps.Treatment diseases caused by exogenous pathogenic factor apoplexy, relieving cough and resolving phlegm, the dissipating blood stasis that dispels the wind, clearing heat and expelling damp, treatment energy-stagnation stomachache, children's's infantile malnutrition.Herba Cymbopogonis: hot, bitter, cold.Go into bladder, lung two warps.The clearing away summer-heat expelling pathogenic factors from the exterior, heat-clearing and toxic substances removing, dampness removing stomach function regulating, relieving cough and asthma.Herba Artemisiae Japonicae: bitter, little sweet, cold.Go into the heart, lung, large intestine three warps.Dispelling wind, heat clearing away, detoxifcation, the parasite killing detoxifcation.Ramulus Salicis Babylonicae: hot, bitter, cold.Go into stomach, bladder, liver three warps.Wind-dispelling heat-dissipating, rash solution pox, clearing away heat-damp and promoting diuresis, reducing swelling and alleviating pain, expelling wind and removing dampness.Ramulus et Folium Tamaricis: sweet, hot, temperature.Go into lung, stomach, the heart three warps.Expelling wind and cold, the cough-relieving of inducing sweat rise the rash of loosing, expelling wind and removing dampness, and the painful abdominal mass that disappears is relieved the effect of alcohol.Fructus Crataegi: sour, sweet, tepor.Go into spleen, stomach, liver three warps.Promoting digestion and removing stagnation, the circulation of qi promoting dissipating blood stasis.Fructus Setariae Germinatus: sweet, temperature.Go into spleen, stomach warp.With in help digestion, spleen benefiting and stimulating the appetite, excessive thirst is hindered in treatment pyretic toxicity dysentery, Tianjin.Rhizoma Iridis Tectori: hot, bitter, cold, poisonous.Go into lung, liver, spleen three warps.Promoting digestion and removing stagnation, blood circulation promoting and blood stasis dispelling, line water detumescence, heat-clearing and toxic substances removing, suppressing the hyperactive liver are only dizzy.Radix Dauci Sativae: sweet, hot, flat.Go into lung, spleen, stomach, kidney four warps.Invigorating the spleen and regulating the stomach, relieving dyspepsia, warming the kidney to invigorate YANG, detoxifcation rash, nourishing the lung to arrest cough.Endothelium Corneum Gigeriae Galli: sweet, flat.Go into spleen, stomach, large intestine, urinary bladder channel.Relieving dyspepsia, the alleviating distention in middle-JIAO spleen invigorating, removing toxic substances and promoting subsidence of swelling, astringent or styptic treatment for spontaneous sweating ending lost.Semen Fagopyri Esculenti: sweet, acid, cold.Go into spleen, stomach, large intestine channel.The appetizing removing food stagnancy, skin ulcer is treated in detoxifcation.Massa Medicata Fermentata: sweet, suffering, temperature.Go into spleen, stomach warp.The treatment diseases caused by exogenous pathogenic factor are got ill from overeating, insufficiency of the spleen distension, galactopoiesis in puerperal, removing food stagnancy dysentery relieving, therapeutic method to keep the adverse QI flowing downwards expectorant.Semen Raphani: hot, sweet, flat.Go into spleen, stomach warp.Promoting digestion and removing stagnation, lowering the adverse-rising QI to relieve dyspnea, expectorant antitussive.Fructus Caricae: sweet, flat.Go into spleen, stomach warp.The pain relieving that helps digestion, the row water conservancy is wet.Fructus cydoniae oblongae: hot, acid, sweet, temperature.Go into spleen, stomach warp.The therapeutic method to keep the adverse QI flowing downwards helps digestion, and deodorization is relieved the effect of alcohol.Radix Puerariae: sweet, hot, flat, nontoxic.Go into stomach, spleen, lung, bladder four warps.Expelling pathogenic factors from muscles is delivered, and relieving restlessness is quenched the thirst, heat-clearing and toxic substances removing.Radix Glycyrrhizae: sweet, flat.Go into 12 warps.Spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.

The specific embodiment

Get Herba Solidaginis 6g, Semen Glycine Germinatum 3g, Radix Helicteris 9g, Herba Cardui Crispi 3g, Herba Hydrocotyles 6g, Herba Equiseti Hiemalis 6g, Herba Eleusines Indicae 9g, Fructus Arctii 6g, Rhizoma Cimicifugae 3g, Rhizoma Zingiberis Recens 9g, Radix Angelicae Dahuricae 9g, Herba Caryopteridis Incanae 3g, Herba Cymbopogonis 6g, Herba Artemisiae Japonicae 3g, Ramulus Salicis Babylonicae 6g, Ramulus et Folium Tamaricis 3g, Fructus Crataegi 9g, Fructus Setariae Germinatus 9g, Rhizoma Iridis Tectori 1g, Radix Dauci Sativae 9g, Endothelium Corneum Gigeriae Galli 6g, Semen Fagopyri Esculenti 9g, Massa Medicata Fermentata 6g, Semen Raphani 6g, Fructus Caricae 9g Fructus cydoniae oblongae 6g, Radix Puerariae 3g and Radix Glycyrrhizae 9g, more than 28 the flavor medicines put into 1800 ml waters together, soaked 35 minutes, slow fire is fried 30 minutes then, filter and remove residue, fried medicinal liquid are the Chinese medicine for the treatment of excessive drinking type acute glomerulonephritis.Boil medicine altogether 390 milliliters of liquid, when the patient of excessive drinking type acute glomerulonephritis need treat, making fluid temperature was 36 ℃, each 130 milliliters, oral, every day three times, two is a course for the treatment of, if symptom is still deposited, obeys for second course for the treatment of again, so that recovery from illness.

Among the 359 routine excessive drinking type acute glomerulonephritis patients, male's 213 examples account for 59.33%; Women's 146 examples account for 40.67%.The male is more than the women.

Table one, 359 routine excessive drinking type acute glomerulonephritis patient's age scopes

Age (year)	19～26	27～36	37～50	51～56
					The example number	13	223	118	5
Percentage ratio	3.62%	62.12%	32.87%	1.39%

Table two, 359 routine excessive drinking type acute glomerulonephritis patient curative effect tables

Curative effect	Cure	Take a turn for the better	Invalid
				The example number	355	4	Do not have
Percentage ratio	98.89%	1.11%	Do not have

Table three, 359 routine excessive drinking type acute glomerulonephritis patients show the course for the treatment of

The treatment natural law	3～6	7～10	11～15	16～21
					The example number	7	258	91	3
Percentage ratio	1.95%	71.87%	25.35%	0.83%

Information slip before and after table four, the 359 routine excessive drinking type acute glomerulonephritis patient treatments

Claims (1)

1. Chinese medicinal preparation method for the treatment of excessive drinking type acute glomerulonephritis, it is characterized in that: get Herba Solidaginis 6 grams, Semen Glycine Germinatum 3 grams, Radix Helicteris 9 grams, Herba Cardui Crispi 3 grams, Herba Hydrocotyles 6 grams, Herba Equiseti Hiemalis's 6 grams, Herba Eleusines Indicae 9 grams, Fructus Arctii 6 grams, Rhizoma Cimicifugae 3 grams, Rhizoma Zingiberis Recens 9 grams, the Radix Angelicae Dahuricae 9 grams, Herba Caryopteridis Incanae 3 grams, Herba Cymbopogonis 6 grams, Herba Artemisiae Japonicae 3 grams, Ramulus Salicis Babylonicae 6 grams, Ramulus et Folium Tamaricis 3 grams, Fructus Crataegi 9 grams, Fructus Setariae Germinatus 9 grams, Rhizoma Iridis Tectori 1 gram, Radix Dauci Sativae 9 grams, Endothelium Corneum Gigeriae Galli 6 grams, Semen Fagopyri Esculenti 9 grams, Massa Medicata Fermentata 6 grams, Semen Raphani 6 grams, Fructus Caricae 9 gram Fructus cydoniae oblongae 6 grams, Radix Puerariae 3 grams and Radix Glycyrrhizae 9 grams, above 28 flavor Chinese medicines are put into 1800 ml waters, soaked 35 minutes, slow fire is fried 30 minutes then, boil medicine altogether 390 milliliters of liquid of filter and remove residue, fried medicinal liquid is the Chinese medicine for the treatment of excessive drinking type acute glomerulonephritis.