Summary of the invention
For overcoming above-mentioned shortcoming, the objective of the invention is to invent a kind of Chinese medicinal preparation method for the treatment of pain type acute glomerulonephritis.Acute glomerulonephritis is called for short acute nephritis, is one group of common glomerule illness.Onset is anxious, is its Clinical symptoms with hematuria, oliguria, albuminuria, edema and hypertension etc.Acute nephritis can be because of due to the Different types of etiopathogenises, and wherein modal is post-streptococcal infection nephritis, and other causes of disease still have antibacterial (as staphylococcus), virus (as hepatitis B virus), protozoon (as plasmodium) etc.Primary disease belongs to " edema due to wind pathogen ", the category of " YANG edema " and " hematuria " in the Chinese medicine " edema ".
Etiology and pathogenesis:Acute glomerulonephritis is main clinical manifestation with hematuria, edema,proteinuria,hypertension.Human liquid's metabolism relies on the logical of lung qi to transfer, the transferring of temper, and opening of kidney qi is entire, thereby makes three warmers bring into play the duty that it is certainly shown disrespect on.Ailment said due to cold or exposure, water are wet in order to experience for the primary disease cause of disease, noxious dampness, damp and hot heresy, invasion and attack flesh table, and internal injury is in lung, impairment of dispersing and descending function of the lung; Or in be attributed to spleen, spleen loses fortuneization; Under injure kidney, kidney loses folding, disturbance in water passage then, and be edema.In the acute nephritis edema stage, the main diseases position is at lung, spleen, based on inhibited pulmonary QI.If hematuria is obvious, how by the damp-heat accumulation bladder, injury of blood collaterals by heat is due to venation is impaired.If the intenseness of heat wind symptom, disturb sun clearly on the wind-fire, dizziness headache then appears, even the evil cards of violating conscience such as convulsions, coma.Spleen-QI failing to rise up, deficiency of kidney-QI, smart closing admittedly, albuminuria then appears in the separating clear and excreting turbid dereliction of duty.So the sick position of primary disease is dirty at lung, spleen, kidney three, syndrome develop be from table and in, reach the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels by the part of the body cavity above the diaphragm housing the heart and lungs, middle Jiao, develop to simulataneous insufficiency and excessive from real.Since prolonged illness, stagnation of QI-blood, " pain is then obstructed, stagnation of QI and blood may bring about pain ", and send out primary disease.
Clinical manifestation:Limbs pain is main.Onset is more anxious, and state of an illness weight does not wait.Most of patients has clear and definite streptococcal infection history, as upper respiratory tract infection, pharyngitis, tonsillitis and skin infection etc.Sudden onset, first symptom mostly is edema and hematuria.1, edema: the lighter only plays blepharoedema morning, and complexion is paler, is " nephritis face ".Weight person prolongs and whole body, and finger pressure skin can not have significant depressions, and body weight also increases thereupon.2, hypertension: see 80% case, mostly be light moderate hypertension, diastolic pressure is less than 14kpa.The hypertension of acute nephritis mostly is a property crossed, and the generation reason is mainly water, sodium retention makes due to the blood volume expansion.3, urine is unusual: 1. oliguria: the most of patients onset has oliguria often, as every day the urine amount be less than 500ml person, slight azotemia can appear.2. hematuria: see all acute nephritis patients, can be gross hematuria, or muddy coffee-like, general persistence is not long, namely transfers microscopic hematuria to.3. albuminuria: most of patients all has 4. whole body performance of albuminuria in various degree: tired, lumbago, anorexia, feel sick, vomiting, the person of being in a bad way can have headache, dizziness, drowsiness, blurred vision etc.Body of the tongue is light red, white and thin fur, hesitant pulse.
Its technical scheme is:Get Flos Camelliae Japonicae 6 weight portions, Herba Cirsii 6 weight portions, Herba Osbeckiae 3 weight portions, Folium Artemisiae Argyi 6 weight portions, Radix et Caulis Opuntiae Dillenii 9 weight portions, Herba Agrimoniae 9 weight portions, Pseudobulbus Bletillae (Rhizoma Bletillae) 6 weight portions, Terra Flava Usta 9 weight portions, Crinis Carbonisatus 3 weight portions, Radix Rumicis Japonici 3 weight portions, Ophicalcitum 6 weight portion Radix Boehmeriaes 9 weight portions, Radix Rubiae 9 weight portions, Herba Salviae Plebeiae 9 weight portions, Flos althaeae roseae 6 weight portions, Herba Ecliptae 6 weight portions, Pericarpium Citri Reticulatae Viride 9 weight portions, Flos Caryophylli 6 weight portions, Fructus Akebiae 6 weight portions, Fructus Anisi Stellati 9 weight portions, Folium Et Cacumen Murrayae 9 weight portions, Aspongopus 3 weight portions, Semen Canavaliae 6 weight portions, Radix Inulae 3 weight portions, Fructus Toosendan 1 weight portion, Semen Caesalpiniae 3 weight portions, the Radix Linderae 6 weight portions, Radix Et Rhizoma Nardostachyos 3 weight portions, Ambra Grisea 3 weight portions, Radix Clematidis 1 weight portion, Herba Gelsemii Elegantis 1 weight portion, Cortex Periplocae 3 weight portions and Radix Glycyrrhizae 9 weight portions, above 33 flavor Chinese medicines are put into 1800 ml waters, soaked 35 minutes, slow fire is fried 30 minutes then, boil medicine altogether 390 milliliters of liquid of filter and remove residue, fried medicinal liquid is the Chinese medicine for the treatment of pain type acute glomerulonephritis.
The advantage of this invention is:We's 33 flavor Chinese medicines all can have been bought in pharmacy, make simply, and the herb liquid toxic and side effects of making is little, short treating period, cure rate height.Monarch, just right.When using Chinese medicine, untoward reaction, anaphylaxis and the toxic reaction of having avoided Western medicine to cause.Flos Camelliae Japonicae, Herba Cirsii, Herba Osbeckiae, Folium Artemisiae Argyi, Radix et Caulis Opuntiae Dillenii, Herba Agrimoniae, Pseudobulbus Bletillae (Rhizoma Bletillae), Terra Flava Usta, Crinis Carbonisatus, Radix Rumicis Japonici, Ophicalcitum, Radix Boehmeriae, Radix Rubiae, Herba Salviae Plebeiae, Flos althaeae roseae, Herba Ecliptae, more than 16 flavor medical instruments the effect of promoting blood circulation and hemostasis, spleen invigorating removing food stagnancy, promoting blood circulation and detumescence, eliminating stasis to stop pain, dispersing cold for relieving pain, stomach function regulating preventing or arresting vomiting is arranged, in the process for the treatment of pain type acute glomerulonephritis, play main therapeutical effect, so be monarch drug.Pericarpium Citri Reticulatae Viride, Flos Caryophylli, Fructus Akebiae, Fructus Anisi Stellati, Folium Et Cacumen Murrayae, Aspongopus, Semen Canavaliae, Radix Inulae, Fructus Toosendan, Semen Caesalpiniae, the Radix Linderae, Radix Et Rhizoma Nardostachyos, Ambra Grisea, more than 13 flavor medical instruments soothing the liver dispelling the stagnated QI is arranged, long-pendingization of loosing is stagnant, consciousness and resuscitation restoring, soothing liver-QI stomach function regulating, promoting the circulation of QI to relieve pain effect.In the process for the treatment of pain type acute glomerulonephritis, can assist principal agent performance therapeutical effect, so be ministerial drug.Radix Clematidis: hot, salty, temperature, poisonous.Go into urinary bladder channel.Expelling wind and removing dampness, hard masses softening and resolving, relieving and eliminating mass.Herba Gelsemii Elegantis: hot, bitter, temperature, poisonous.Go into the heart, lung, large intestine, small intestinal four warps.Expelling wind and removing dampness, hard masses softening and resolving, reducing swelling and alleviating pain, the detoxifcation parasite killing, diuretic is relievingd asthma.Cortex Periplocae: hot, bitter, tepor, poisonous.Go into liver, kidney, the heart three warps.The sharp numbness of warming YANG, the beneficial heart is relievingd asthma, and the kidney warming is controlled something lost, and tonifying YANG plays flaccidity.More than the through focus of 3 flavor medicine energy rates all medicines, so be adjuvant drug.Radix Glycyrrhizae: sweet, flat.Go into 12 warps.The spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.Can entangle the bias of all medicines, can alleviate the toxicity of all medicines again, so for making medicine.Flos Camelliae Japonicae, Herba Cirsii, Herba Osbeckiae, Folium Artemisiae Argyi, Radix et Caulis Opuntiae Dillenii, Herba Agrimoniae, Pseudobulbus Bletillae (Rhizoma Bletillae), Terra Flava Usta, Crinis Carbonisatus, Radix Rumicis Japonici, Ophicalcitum Radix Boehmeriae, Radix Rubiae, Herba Salviae Plebeiae, Flos althaeae roseae, Herba Ecliptae, Pericarpium Citri Reticulatae Viride, Flos Caryophylli, Fructus Akebiae, Fructus Anisi Stellati, Folium Et Cacumen Murrayae, Aspongopus, Semen Canavaliae, Radix Inulae, Fructus Toosendan, Semen Caesalpiniae, the Radix Linderae, Radix Et Rhizoma Nardostachyos, Ambra Grisea, Radix Clematidis, Herba Gelsemii Elegantis, Cortex Periplocae, Radix Glycyrrhizae, this 33 flavor medicine compatibility is used, and plays promoting blood circulation and hemostasis jointly, the spleen invigorating removing food stagnancy, promoting blood circulation and detumescence, eliminating stasis to stop pain, dispersing cold for relieving pain, long-pendingization of loosing stagnates, consciousness and resuscitation restoring, the soothing liver-QI stomach function regulating, the effect of promoting the circulation of QI to relieve pain.Monarch, compatibility is proper, is the optimum formula for the treatment of pain type acute glomerulonephritis.Flos Camelliae Japonicae: sweet, bitter, hot, cold.Go into liver, lung, large intestine channel.Skin ulcer is treated in cooling blood for hemostasis, blood circulation promoting and blood stasis dispelling, detoxifcation.Herba Cirsii: sweet, little hardship, cold.Go into liver, spleen, urinary bladder channel.Cooling blood for hemostasis, promoting blood circulation and detoxication, inducing diuresis for treating stranguria syndrome.Herba Osbeckiae: suffering, flat.Go into lung, large intestine, Liver Channel.The hemostasis repercussive, clearing away heat and eliminating dampness, relieving cough and asthma, blood stasis dispelling dispels the wind.Folium Artemisiae Argyi: hot, bitter, temperature.Go into the liver,spleen,kidney warp.Warming the meridian for stopping bleeding, dispersing cold for relieving pain, regulating menstruation are antiabortive, removing damp to relieve itching, dredge the meridian passage.Radix et Caulis Opuntiae Dillenii: hardship, cold.Go into the heart, lung, stomach warp.Promoting flow of QI and blood, heat-clearing and toxic substances removing, evacuation of pus granulation promoting, cooling blood for hemostasis, clearing away lung-heat to relieve cough.Herba Agrimoniae: bitter, puckery, little sweet, flat.Go into lung, liver, spleen, large intestine channel.Astringing to arrest bleeding, tonify deficiency dysentery relieving, parasite killing detoxifcation, preventing the attack (or recurrence) of malaria, promoting blood circulation and detumescence.Pseudobulbus Bletillae (Rhizoma Bletillae): bitter, sweet, puckery, be slightly cold.Go into lung, liver, stomach warp.Astringing to arrest bleeding, swollen clearly granulation promoting, parasite killing are held back skin ulcer.Terra Flava Usta: suffering, tepor.Go into spleen, stomach, Liver Channel.Warming middle-JIAO hemostasis, stomach function regulating preventing or arresting vomiting, warming the spleen astringing intestine to stop diarrhea.Crinis Carbonisatus: hardship, flat.Go into liver, stomach warp.Hemostasis dissipating blood stasis, nourishing YIN diuresis, promoting tissue regeneration and ulcer healing.Radix Rumicis Japonici: hardship, cold, mild toxicity.Go into spleen, liver, large intestine, urinary bladder channel.Cooling blood for hemostasis, parasite killing are treated tinea, expelling pathogenic heat to loosen the bowels.Ophicalcitum: sour, puckery, flat.Go into Liver Channel.Astringing to arrest bleeding, hemostasis by removing blood stasis.Radix Boehmeriae: sweet, cold.Go into the heart, Liver Channel.Cooling blood for hemostasis, heat-clearing and toxic substances removing, clearing heat and preventing abortion, clearing away heat and promoting diuresis.Radix Rubiae: bitter, salty, sour, cold.Go into liver, the heart, spleen, stomach, lung meridian.Cooling blood for hemostasis, blood circulation promoting and blood stasis dispelling, dispelling wind collateral dredging, heat clearing away jaundice eliminating, eliminating phlegm and stopping cough.Herba Salviae Plebeiae: hot, bitter, cold.Go into the heart, liver, kidney channel.Cooling blood for hemostasis, inducing diuresis to remove edema, detoxifcation parasite killing.Flos althaeae roseae: sweet, salty, cold, nontoxic.Go into spleen, stomach, kidney channel.Promoting blood circulation and hemostasis, clearing away heat-damp and promoting diuresis, moistening dryness for relaxing bowels, detoxicating and resolving stagnation of pathogens.Herba Ecliptae: sweet, sour, cold.Go into liver, kidney, stomach, large and small intestinal warp.Cooling blood for hemostasis, yin nourishing black hair, removing dampness to relieve itching.Pericarpium Citri Reticulatae Viride: bitter, hot, warm.Go into liver, gallbladder meridian.Soothing the liver dispelling the stagnated QI, long-pendingization of loosing stagnates.Flos Caryophylli: suffering, temperature.Go into spleen, stomach, kidney channel.Warming middle-JIAO to send down the adverse QI, the warming the kidney tonifying YANG, promoting the circulation of QI to relieve pain, consciousness and resuscitation restoring is warded off dirty parasite killing.Fructus Akebiae: sweet, cold.Go into liver, stomach warp.The soothing liver-QI stomach function regulating, promoting blood circulation and stopping pain, inducing diuresis for treating stranguria syndrome is separated tired quenching the thirst.Fructus Anisi Stellati: hot, sweet, temperature.Go into liver,kidney,spleen, stomach warp.Warming spleen and stomach for dispelling cold, promoting the circulation of QI to relieve pain, warming and recuperating the kidney-YANG is warded off the evil dirt eliminating.Folium Et Cacumen Murrayae: hot, bitter, temperature.Go into the heart, liver, lung meridian.Promoting the circulation of QI to relieve pain, promoting blood circulation to remove blood stasis, expelling wind and removing dampness, hard masses softening and resolving.Aspongopus: salty, sweet, temperature, nontoxic.Go into the liver,spleen,kidney warp.Promoting the circulation of QI to relieve pain, warming the kidney to invigorate YANG, warming middle-JIAO to stop diarrhea.Semen Canavaliae: sweet, flat, nontoxic.Go into spleen, stomach, large intestine, kidney channel.Warming the middle warmer and descending qi, kidney tonifying complement, eliminating phlegm and relieving asthma, promoting the circulation of QI to relieve pain.Radix Inulae: hot, bitter, temperature.Go into lung, liver, spleen channel.Invigorating the spleen and regulating the stomach, promoting the circulation of QI to relieve pain are got rid of evils and are controlled algid malaria, the peace ascarifuge.Fructus Toosendan: hardship, cold, slightly poisonous.Go into liver, stomach, small intestinal, urinary bladder channel.Removing dampness and killing parasites, promoting the circulation of QI to relieve pain, clearing heat, purging intense-heat.Semen Caesalpiniae: suffering, temperature.Go into lung, large intestine channel.Promoting the circulation of QI to relieve pain, preventing the attack (or recurrence) of malaria is only quenched one's thirst.The Radix Linderae: suffering, temperature.Go into lung, spleen, kidney, urinary bladder channel.Promoting the circulation of QI to relieve pain, warming kidney for dispelling cold.Radix Et Rhizoma Nardostachyos: hot, sweet, temperature.Go into spleen, stomach warp.Promoting the circulation of QI to relieve pain, activating spleen and strengthening stomach, removing dampness is drawn out pus by applying a plaster to the affected part.Ambra Grisea: sweet, sour, gas raw meat, tepor.Go into the heart, lung, liver, kidney channel.Promoting flow of QI and blood, relieving stranguria by diuresis, relieving cough and asthma promotes the production of body fluid and is full of cheek, wards off dirty detoxifcation.Radix Clematidis: hot, salty, temperature, poisonous.Go into urinary bladder channel.Expelling wind and removing dampness, hard masses softening and resolving, relieving and eliminating mass.Herba Gelsemii Elegantis: hot, bitter, temperature, poisonous.Go into the heart, lung, large intestine, small intestinal four warps.Expelling wind and removing dampness, hard masses softening and resolving, reducing swelling and alleviating pain, the detoxifcation parasite killing, diuretic is relievingd asthma.Cortex Periplocae: hot, bitter, tepor, poisonous.Go into liver, kidney, the heart three warps.The sharp numbness of warming YANG, the beneficial heart is relievingd asthma, and the kidney warming is controlled something lost, and tonifying YANG plays flaccidity.Radix Glycyrrhizae: sweet, flat.Go into 12 warps.The spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.