CN102813848B - Preparation method of traditional Chinese medicine for treating vomit type acute glomerulonephritis - Google Patents

Abstract

The invention relates to a preparation method of a traditional Chinese medicine for treating vomit type acute glomerulonephritis, belonging to the technical field of preparation methods of traditional Chinese medicines. At present, penicillin is generally adopted for treating vomit type acute glomerulonephritis, but penicillin can easily cause allergic reaction, and especially allergic shock. Thetechnical scheme adopted in the invention is as follows: taking Japanese ginseng, almond, folium eriobotryae, Momordica grosvenori, adenophora tetraphylla, root of apricotleaf ladybell, bamboo juice,pinellia ternata, exocarpium, concha arcae, oroxylum indicum, pericarpium citri reticulatae viride, lilac, fiveleaf akebia fruit, fructus anisi stellati, camuning, aspongopus, sword bean, scabwort, szechwan Chinaberry fruit, mysorethorn, the root of three-nerved spicebush, rhizoma nardostachyos, ambergris, caulis bambusae in taeniam and liquorice, soaking the 26 kinds of traditional Chinese medicines in water, and decocting with slow fire, wherein the decocted liquid medicine is the traditional Chinese medicine for treating vomit type acute glomerulonephritis. The prepared traditional Chineseliquid medicine has the advantages of short course of treatment and high cure rate. Assistant and guide are achieved so that the function is just right. When the traditional Chinese medicine for treating vomit type acute glomerulonephritis is applied, adverse reaction, allergic reaction and toxic reaction caused by Western medicines are avoided.

Description

A kind of Chinese medicinal preparation method for the treatment of vomiting type acute glomerulonephritis

Technical field

The present invention relates to the Chinese medicinal preparation method technical field, is a kind of Chinese medicinal preparation method for the treatment of vomiting type acute glomerulonephritis more specifically.

Background technology

The type for the treatment of vomiting at present acute glomerulonephritis, the general employing: 1, penicillin: allergy easily takes place in this product, anaphylactic shock (the most dangerous anaphylactic shock particularly, can occur in and do tuerculoderma at that time, only a few can occur in the continuous use process, the Delayed Hypersensitivity shock), as untimely rescue, can critical life, thus all to improve protection before, during and after the medication, so as to avoid an accident.Attention: before the application, must ask to have or not anaphylactic disease clearly, with having or not allergy such as erythra, heating to occur behind the penicillin, must do the penicillin skin test earlier.2, amoxicillin: accidental erythra, oral can have nauseating, epigastric discomfort, diarrhoea etc. after a large amount of; Pseudomembranous colitis.3, carbenicillin: various types of allergy can occur.May cause neural poison reaction, pulmonary edema after heavy dose of administration, may occur the transience transaminase during the medication and raise and granulocytopenia.4, reserpine: nasal obstruction, gastric acid secretion increase, times of defecation increases and aroused in interest slack-off etc., even apathetic expression can appear in long-term extensive application, drowsiness, spirit depressing causes extrapyramidal symptoms, the performance muscular tremor.1. to activeness Peptic Ulcers and dysthymia person's forbidding; 2. reserpine can enter fetal tissue by Placenta Hominis, if the antenatal application of anemia of pregnant woman can cause neonate nasal obstruction, respiratory tract obstruction, should try one's best need not.5, bendazol: headache, hyperhidrosis, heating sense are arranged.6, captopril: important side effect is Toxicity of Kidney and granulocytopenia, is erythra, dysgeusia and cough secondly.Heavy dose can cause hemodynamic change, symptomatic hypotension etc.7, hydrochlorothiazide: the low blood chlorine of 1. hypokalemia, and normal companion, hypomagnesemia, hypokalemia can bring out hepatic coma and Folium Digitalis Purpureae institute proarrhythmia, needs timely kalium replenishment or add to stay the potassium diuretic; 2. hyperglycemia reduces carbohydrate tolerance; 3. symptom can be brought out or increase the weight of to hyperuricemia to the goat image; 4. azotemia because reducing glomerular filtration rate, increases the weight of azotemia and renal function is further worsened the renal insufficiency patient, and this product diuretic effect is poor, so the careful usefulness of renal failure patient or forbidding; 5. ammonirrhea reduces, and may make H because suppressing carbonic anhydrase ⁺Secretion reduces, and the ammonia secretion also reduces.During hepatic disfunction, can bring out hepatic coma; 6. parathyroid gland effect: take for a long time and can cause hypercalcemia, low serum p disease and parathyroid hyperplasia; 7. other: skin erythema, photoallergic dermatitis, pancreatitis, intrahepatic cholestasis, bone marrow depression, especially thrombocytopenia can cause the announcements that all appear in the newspapers such as purpura, neutrophilic granulocyte minimizing, hemolytic anemia of newborn, the serum antinuclear antibody positive.

Summary of the invention

For overcoming above-mentioned shortcoming, the objective of the invention is to invent a kind of Chinese medicinal preparation method for the treatment of vomiting type acute glomerulonephritis.Acute glomerulonephritis is called for short acute nephritis, is one group of common glomerule illness.Onset is anxious, is its Clinical symptoms with hematuria, oliguria, albuminuria, edema and hypertension etc.Acute nephritis can be because of due to the Different types of etiopathogenises, and wherein modal is post-streptococcal infection nephritis, and other causes of disease still have antibacterial (as staphylococcus), virus (as hepatitis B virus), protozoon (as plasmodium) etc.Primary disease belongs to " edema due to wind pathogen ", the category of " YANG edema " and " hematuria " in the Chinese medicine " edema ".

Etiology and pathogenesis:Acute glomerulonephritis is main clinical manifestation with hematuria, edema,proteinuria,hypertension.Human liquid's metabolism relies on the logical of lung qi to transfer, the transferring of temper, and opening of kidney qi is entire, thereby makes three warmers bring into play the duty that it is certainly shown disrespect on.Ailment said due to cold or exposure, water are wet in order to experience for the primary disease cause of disease, noxious dampness, damp and hot heresy, invasion and attack flesh table, and internal injury is in lung, impairment of dispersing and descending function of the lung; Or in be attributed to spleen, spleen loses fortuneization; Under injure kidney, kidney loses folding, disturbance in water passage then, and be edema.In the acute nephritis edema stage, the main diseases position is at lung, spleen, based on inhibited pulmonary QI.If hematuria is obvious, how by the damp-heat accumulation bladder, injury of blood collaterals by heat is due to venation is impaired.If the intenseness of heat wind symptom, disturb sun clearly on the wind-fire, dizziness headache then appears, even the evil cards of violating conscience such as convulsions, coma.Spleen-QI failing to rise up, deficiency of kidney-QI, smart closing admittedly, albuminuria then appears in the separating clear and excreting turbid dereliction of duty.So the sick position of primary disease is dirty at lung, spleen, kidney three, syndrome develop be from table and in, reach the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels by the part of the body cavity above the diaphragm housing the heart and lungs, middle Jiao, develop to simulataneous insufficiency and excessive from real.Because overstrain is too, consumption damaging the spleen and stomach gas, or prolonged illness hypoactivity of YANG in middle-JIAO, spleen loses and builds fortune, stomach-QI being unable to descend normally, and cause primary disease.

Clinical manifestation:Vomiting very.Onset is more anxious, and state of an illness weight does not wait.Most of patients has clear and definite streptococcal infection history, as upper respiratory tract infection, pharyngitis, tonsillitis and skin infection etc., and sudden onset, first symptom mostly is edema and hematuria.1, edema: the lighter only plays blepharoedema morning, and complexion is paler, is " nephritis face ".Weight person prolongs and whole body, and finger pressure skin can not have significant depressions, and body weight also increases thereupon.2, hypertension: see 80% case, mostly be light moderate hypertension, diastolic pressure is less than 14kpa.The hypertension of acute nephritis mostly is a property crossed, and the generation reason is mainly water, sodium retention makes due to the blood volume expansion.3, urine is unusual: 1. oliguria: the most of patients onset has oliguria often, as every day the urine amount be less than 500ml person, slight azotemia can appear.2. hematuria: see all acute nephritis patients, can be gross hematuria, or muddy coffee-like, general persistence is not long, namely transfers microscopic hematuria to.3. albuminuria: most of patients all has 4. whole body performance of albuminuria in various degree: tired, lumbago, anorexia, feel sick, vomiting, the person of being in a bad way can have headache, dizziness, drowsiness, blurred vision etc.Red tongue, yellow fur, rapid pulse.

Its technical scheme is:Get Rhizoma Panacis japonici 3 weight portions, Semen Armeniacae Amarum 9 weight portions, Folium Eriobotryae 6 weight portions, Fructus Momordicae 6 weight portions, Radix Adenophorae 3 weight portion Radix Adenophorae Trachelioidis 6 weight portions, Succus Bambusae 6 weight portions, the Rhizoma Pinelliae 1 weight portion, Exocarpium Citri Grandis 3 weight portions, Concha Arcae 6 weight portions, Semen Oroxyli 6 weight portions, Pericarpium Citri Reticulatae Viride 9 weight portions, Flos Caryophylli 6 weight portions, Fructus Akebiae 6 weight portions, Fructus Anisi Stellati 9 weight portions, Folium Et Cacumen Murrayae 9 weight portions, Aspongopus 3 weight portions, Semen Canavaliae 6 weight portions, Radix Inulae 3 weight portions, Fructus Toosendan 3 weight portions, Semen Caesalpiniae 3 weight portions, the Radix Linderae 6 weight portions, Radix Et Rhizoma Nardostachyos 3 weight portions, Ambra Grisea 3 weight portions, Caulis Bambusae In Taenia 9 weight portions and Radix Glycyrrhizae 9 weight portions, above 26 flavor Chinese medicines are put into 1800 ml waters, soaked 35 minutes, slow fire is fried 30 minutes then, boil medicine altogether 390 milliliters of liquid of filter and remove residue, fried medicinal liquid is the Chinese medicine for the treatment of vomiting type acute glomerulonephritis.

The advantage of this invention is:We's 26 flavor Chinese medicines all can have been bought in pharmacy, make simply, and the herb liquid toxic and side effects of making is little, short treating period, cure rate height.Monarch, just right.When using Chinese medicine, untoward reaction, anaphylaxis and the toxic reaction of having avoided Western medicine to cause.Rhizoma Panacis japonici, Semen Armeniacae Amarum, Folium Eriobotryae, Fructus Momordicae, Radix Adenophorae, Radix Adenophorae Trachelioidis, Succus Bambusae, the Rhizoma Pinelliae, Exocarpium Citri Grandis, Concha Arcae, Semen Oroxyli, more than 11 the flavor medical instruments clearing away heat and cooling blood is arranged, clearing heat and relieving fidgetness, heat-clearing and toxic substances removing, evacuation of pus detumescence, dispelling wind for relieving itching, heat-clearing and toxic substances removing, promoting the production of body fluid to quench thirst, the effect of relieving gastric hyperacidity to alleviate stomachache.In the process for the treatment of vomiting type acute glomerulonephritis, play main therapeutical effect, so be monarch drug.Pericarpium Citri Reticulatae Viride, Flos Caryophylli, Fructus Akebiae, Fructus Anisi Stellati, Folium Et Cacumen Murrayae, Aspongopus, Semen Canavaliae, Radix Inulae, Fructus Toosendan, Semen Caesalpiniae, the Radix Linderae, Radix Et Rhizoma Nardostachyos, Ambra Grisea, more than 13 flavor medical instruments soothing the liver dispelling the stagnated QI is arranged, long-pendingization of loosing stagnates, consciousness and resuscitation restoring, soothing liver-QI stomach function regulating, solution be tired of quench the thirst, the therapeutic method to keep the adverse QI flowing downwards, kidney tonifying complement, promoting the circulation of QI to relieve pain effect.In the process for the treatment of vomiting type acute glomerulonephritis, can assist principal agent performance therapeutical effect, so be ministerial drug.Caulis Bambusae In Taenia: bitter, sweet, hot, be slightly cold.Go into gallbladder, stomach, bladder, spleen, lung, heart the six channels.Clearing away heat and cooling blood, regulating the stomach and sending down the abnormal ascending QI, preventing phlegm from forming and stopping coughing, clearing heat and relieving fidgetness.The all medicines of the energy rate focus of going directly is so be adjuvant drug.Radix Glycyrrhizae: sweet, flat.Go into 12 warps.The spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.Can entangle the bias of all medicines, can alleviate the toxicity of all medicines again, so for making medicine.Rhizoma Panacis japonici, Semen Armeniacae Amarum, Folium Eriobotryae, Fructus Momordicae, Radix Adenophorae, Radix Adenophorae Trachelioidis, Succus Bambusae, the Rhizoma Pinelliae, Exocarpium Citri Grandis, Concha Arcae, Semen Oroxyli, Pericarpium Citri Reticulatae Viride, Flos Caryophylli, Fructus Akebiae, Fructus Anisi Stellati, Folium Et Cacumen Murrayae, Aspongopus, Semen Canavaliae, Radix Inulae, Fructus Toosendan, Semen Caesalpiniae, the Radix Linderae, Radix Et Rhizoma Nardostachyos, Ambra Grisea, Caulis Bambusae In Taenia, Radix Glycyrrhizae.This 26 flavor medicine compatibility is used, and plays clearing away heat and cooling blood jointly, clearing heat and relieving fidgetness, and promoting blood circulation and hemostasis, heat-clearing and toxic substances removing, the evacuation of pus detumescence, dispelling wind for relieving itching, promoting the production of body fluid to quench thirst, relieving gastric hyperacidity to alleviate stomachache, soothing the liver dispelling the stagnated QI, long-pendingization of loosing stagnates, consciousness and resuscitation restoring, soothing liver-QI stomach function regulating, the effect of kidney tonifying complement, promoting the circulation of QI to relieve pain.Monarch, compatibility is proper, is the optimum formula for the treatment of vomiting type acute glomerulonephritis.Rhizoma Panacis japonici: sweet, bitter, temperature.Go into lung, liver, spleen three warps.Relieving cough and resolving phlegm, promoting blood circulation and hemostasis.Semen Armeniacae Amarum: bitter, sweet, flat.Go into lung meridian.Relieving cough and asthma, dryness of the intestine constipation, following air to open numbness, damp-heat gonorrhoea, scabies.Folium Eriobotryae: hardship is slightly cold.Go into lung, stomach two warps.Qinghua heat-phlegm, relieving cough and asthma, regulating the stomach and sending down the abnormal ascending QI, heat-clearing and toxic substances removing.Fructus Momordicae: sweet, cold.Go into lung, spleen two warps.Clearing away lung-heat to relieve cough, cooling blood for hemostasis, the intestine moistening of promoting the production of body fluid.Radix Adenophorae: sweet, little hardship is slightly cold.Go into lung, stomach, liver three warps.Clearing lung and nourishing yin, expelling phlegm for arresting cough, reinforcing stomach reg fluid, evacuation of pus detumescence, dispelling wind for relieving itching.Radix Adenophorae Trachelioidis: sweet, cold.Go into lung, stomach, spleen, kidney four warps.Preventing phlegm from forming and stopping coughing, heat-clearing and toxic substances removing, promoting the production of body fluid to quench thirst, nourishing yin and purging fire.Succus Bambusae: sweet, light, bitter, cold.Go into the heart, lung, stomach, liver four warps.Clearing heat and dispersing phlegm is relieving convulsionly had one's ideas straightened out.The Rhizoma Pinelliae: hot, bitter, temperature, poisonous.Go into spleen, stomach two warps.Drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.Exocarpium Citri Grandis: hot, bitter, temperature.Go into spleen, lung two warps.Regulate the flow of vital energy and transfer, drying dampness to eliminate phlegm.Concha Arcae: salty, hot, flat.Go into lung, liver, spleen, stomach four warps.Eliminating phlegm and softening indurated mass, dissipating phlegm and resolving masses, relieving gastric hyperacidity to alleviate stomachache.Semen Oroxyli: hardship, cold.Go into lung, liver two warps.The lung moistening granulation promoting, the soothing liver-QI stomach function regulating.Pericarpium Citri Reticulatae Viride: bitter, hot, warm.Go into liver, gallbladder meridian.Soothing the liver dispelling the stagnated QI, long-pendingization of loosing stagnates.Flos Caryophylli: suffering, temperature.Go into spleen, stomach, kidney channel.Warming middle-JIAO to send down the adverse QI, the warming the kidney tonifying YANG, promoting the circulation of QI to relieve pain, consciousness and resuscitation restoring is warded off dirty parasite killing.Fructus Akebiae: sweet, cold.Go into liver, stomach warp.The soothing liver-QI stomach function regulating, promoting blood circulation and stopping pain, inducing diuresis for treating stranguria syndrome is separated tired quenching the thirst.Fructus Anisi Stellati: hot, sweet, temperature.Go into liver,kidney,spleen, stomach warp.Warming spleen and stomach for dispelling cold, promoting the circulation of QI to relieve pain, warming and recuperating the kidney-YANG is warded off the evil dirt eliminating.Folium Et Cacumen Murrayae: hot, bitter, temperature.Go into the heart, liver, lung meridian.Promoting the circulation of QI to relieve pain, promoting blood circulation to remove blood stasis, expelling wind and removing dampness, hard masses softening and resolving.Aspongopus: salty, sweet, temperature, nontoxic.Go into the liver,spleen,kidney warp.Promoting the circulation of QI to relieve pain, warming the kidney to invigorate YANG, warming middle-JIAO to stop diarrhea.Semen Canavaliae: sweet, flat, nontoxic.Go into spleen, stomach, large intestine, kidney channel.Warming the middle warmer and descending qi, kidney tonifying complement, eliminating phlegm and relieving asthma, promoting the circulation of QI to relieve pain.Radix Inulae: hot, bitter, temperature.Go into lung, liver, spleen channel.Invigorating the spleen and regulating the stomach, promoting the circulation of QI to relieve pain are got rid of evils and are controlled algid malaria, the peace ascarifuge.Fructus Toosendan: hardship, cold, slightly poisonous.Go into liver, stomach, small intestinal, urinary bladder channel.Removing dampness and killing parasites, promoting the circulation of QI to relieve pain, clearing heat, purging intense-heat.Semen Caesalpiniae: suffering, temperature.Go into lung, large intestine channel.Promoting the circulation of QI to relieve pain, preventing the attack (or recurrence) of malaria is only quenched one's thirst.The Radix Linderae: suffering, temperature.Go into lung, spleen, kidney, urinary bladder channel.Promoting the circulation of QI to relieve pain, warming kidney for dispelling cold.Radix Et Rhizoma Nardostachyos: hot, sweet, temperature.Go into spleen, stomach warp.Promoting the circulation of QI to relieve pain, activating spleen and strengthening stomach, removing dampness is drawn out pus by applying a plaster to the affected part.Ambra Grisea: sweet, sour, gas raw meat, tepor.Go into the heart, lung, liver, kidney channel.Promoting flow of QI and blood, relieving stranguria by diuresis, relieving cough and asthma promotes the production of body fluid and is full of cheek, wards off dirty detoxifcation.Caulis Bambusae In Taenia: bitter, sweet, hot, be slightly cold.Go into gallbladder, stomach, bladder, spleen, lung, heart the six channels.Clearing away heat and cooling blood, regulating the stomach and sending down the abnormal ascending QI, preventing phlegm from forming and stopping coughing, clearing heat and relieving fidgetness.Radix Glycyrrhizae: sweet, flat.Go into 12 warps.The spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.

The specific embodiment

Get Rhizoma Panacis japonici 3g, Semen Armeniacae Amarum 9g, Folium Eriobotryae 6g, Fructus Momordicae 6g, Radix Adenophorae 3g Radix Adenophorae Trachelioidis 6g, Succus Bambusae 6g, Rhizoma Pinelliae 1g, Exocarpium Citri Grandis 3g, Concha Arcae 6g, Semen Oroxyli 6g, Pericarpium Citri Reticulatae Viride 9g, Flos Caryophylli 6g, Fructus Akebiae 6g, Fructus Anisi Stellati 9g, Folium Et Cacumen Murrayae 9g, Aspongopus 3g, Semen Canavaliae 6g, Radix Inulae 3g, Fructus Toosendan 3g, Semen Caesalpiniae 3g, Radix Linderae 6g, Radix Et Rhizoma Nardostachyos 3g, Ambra Grisea 3g, Caulis Bambusae In Taenia 9g and Radix Glycyrrhizae 9g, more than 26 the flavor medicines put into 1800 ml waters together, soaked 35 minutes, slow fire is fried 30 minutes then, filter and remove residue, fried medicinal liquid are the Chinese medicine for the treatment of vomiting type acute glomerulonephritis.Boil medicine altogether 390 milliliters of liquid, when the patient of vomiting type acute glomerulonephritis need treat, making fluid temperature was 36 ℃, each 130 milliliters, oral, every day three times, two is a course for the treatment of, if symptom is still deposited, obeys for second course for the treatment of again, so that recovery from illness.

Among the 355 routine vomiting type acute glomerulonephritis patients, male's 152 examples account for 42.82%; Women's 203 examples account for 57.18%.The women is more than the male.

Table one, 355 routine vomiting type acute glomerulonephritis patient's age scopes

Age (year)	17～20	21～30	31～40	41～50
					The example number	9	177	163	6
Percentage ratio	2.53%	49.86%	45.92%	1.69%

Table two, 355 routine vomiting type acute glomerulonephritis patient curative effect tables

Curative effect	Cure	Take a turn for the better	Invalid
				The example number	352	3	Do not have
Percentage ratio	99.15%	0.85%	Do not have

Table three, 355 routine vomiting type acute glomerulonephritis patients show the course for the treatment of

The treatment natural law	3～5	6～10	11～15	16～20
					The example number	7	250	93	5
Percentage ratio	1.97%	70.42%	26.2%	1.41%

Information slip before and after table four, the 355 routine vomiting type acute glomerulonephritis patient treatments

Claims (1)

1. Chinese medicinal preparation method for the treatment of vomiting type acute glomerulonephritis, it is characterized in that: get Rhizoma Panacis japonici 3 grams, Semen Armeniacae Amarum 9 grams, Folium Eriobotryae 6 grams, Fructus Momordicae 6 grams, Radix Adenophorae 3 gram Radix Adenophorae Trachelioidis 6 grams, Succus Bambusae 6 grams, the Rhizoma Pinelliae 1 gram, Exocarpium Citri Grandis 3 grams, Concha Arcae 6 grams, Semen Oroxyli 6 grams, Pericarpium Citri Reticulatae Viride 9 grams, Flos Caryophylli 6 grams, Fructus Akebiae 6 grams, Fructus Anisi Stellati 9 grams, Folium Et Cacumen Murrayae 9 grams, Aspongopus 3 grams, Semen Canavaliae 6 grams, Radix Inulae 3 grams, Fructus Toosendan 3 grams, Semen Caesalpiniae 3 grams, the Radix Linderae 6 grams, Radix Et Rhizoma Nardostachyos 3 grams, Ambra Grisea 3 grams, Caulis Bambusae In Taenia 9 grams and Radix Glycyrrhizae 9 grams, above 26 flavor Chinese medicines are put into 1800 ml waters, soaked 35 minutes, slow fire is fried 30 minutes then, boil medicine altogether 390 milliliters of liquid of filter and remove residue, fried medicinal liquid is the Chinese medicine for the treatment of vomiting type acute glomerulonephritis.