CN102813881B - Preparation method of traditional Chinese medicine for treating abdominal distension type acute glomerulonephritis - Google Patents

Abstract

The invention relates to a preparation method of a traditional Chinese medicine for treating abdominal distension type acute glomerulonephritis, belonging to the technical field of preparation methods of traditional Chinese medicines. At present, reserpine is generally adopted for treating abdominal distension type acute glomerulonephritis, and the disadvantages of reserpine comprise increased gastric acid secretion, increased defecate frequency, slow heartbeat and the like, and long-term administration of reserpine can cause apathia, deprementia, or even cause extrapyramidal system symptoms. The technical scheme adopted in the invention is as follows: taking pericarpium citri reticulatae viride, lilac, fiveleaf akebia fruit, fructus anisi stellati, camuning, aspongopus, sword bean, scabwort, szechwan chinaberry fruit, caesalpinia sepiaria, the root of three-nerved spicebush, rhizoma nardostachyos, ambergris, radix curcumae, cactus, hairyvein agrimony, rhizoma bletillae, furnace soil, carbonized human hair, rumex japonicus, marmor serpentinatum, radix boehmeriae, madder, common sage herb, flower of hollyhock, eclipta, pericarpium arecae and liquorice, soaking the 28 kinds of traditional Chinese medicines in water, and decocting with slow fire, wherein the decocted liquid medicine is the traditional Chinese medicine for treating abdominal distension type acute glomerulonephritis. The traditional Chinese medicine for treating abdominal distension type acute glomerulonephritis has the advantages of short course of treatment and high cure rate. Assistant and guide are achieved so that the function is just right.

Description

A kind of Chinese medicinal preparation method for the treatment of abdominal distension type acute glomerulonephritis

Technical field

The present invention relates to Chinese medicinal preparation method technical field, more specifically a kind of Chinese medicinal preparation method for the treatment of abdominal distension type acute glomerulonephritis.

Background technology

Treat at present abdominal distension type acute glomerulonephritis, general employing: 1, reserpine: nasal obstruction, gastric acid secretion increase, times of defecation increases and aroused in interest slack-off etc., even long-term extensive application can occur that apathetic expression, drowsiness, spirit depressing cause extrapyramidal symptoms, performance muscular tremor.1. to activeness Peptic Ulcers and dysthymia person's forbidding; 2. reserpine can enter fetal tissue by Placenta Hominis, if the antenatal application of anemia of pregnant woman can cause neonate nasal obstruction, respiratory tract obstruction, should need not as far as possible.2, penicillin: allergy easily occurs this product, anaphylactic shock (the most dangerous anaphylactic shock particularly, can occur in and do tuerculoderma at that time, only a few can occur in continuous use process, Delayed Hypersensitivity shock), as rescued not in time, can critical life, therefore all will improve protection before, during and after medication, so as to avoid an accident.Attention: before application, must ask and have or not clearly anaphylactic disease, with having or not the allergy such as erythra, heating to occur after penicillin, must first do penicillin skin test.3, amoxicillin: accidental erythra, oral can have the symptoms such as nauseating, epigastric discomfort, diarrhoea after a large amount of; Pseudomembranous colitis.4, carbenicillin: can occur various types of allergy.After heavy dose of administration, may cause neural poison reaction, pulmonary edema, during medication, may occur that transience transaminase raises and granulocytopenia.5, bendazol: have headache, hyperhidrosis, heating sense.6, secondly captopril: important side effect is Toxicity of Kidney and granulocytopenia is erythra, dysgeusia and cough.Heavy dose can cause hemodynamic change, symptomatic hypotension etc.

Summary of the invention

For overcoming above-mentioned shortcoming, the object of the invention is to invent a kind of Chinese medicinal preparation method for the treatment of abdominal distension type acute glomerulonephritis.Acute glomerulonephritis, is called for short acute nephritis, is one group of common glomerule illness.Onset is anxious, and take hematuria, oliguria, albuminuria, edema and hypertension etc. is its Clinical symptoms.Acute nephritis can be because of due to Different types of etiopathogenises, and wherein modal is post-streptococcal infection nephritis, and other causes of disease still have antibacterial (as staphylococcus), virus (as hepatitis B virus), protozoon (as plasmodium) etc.Primary disease belongs to " edema due to wind pathogen ", the category of " YANG edema " and " hematuria " in Chinese medicine " edema ".

etiology and pathogenesis: anxiousit is main clinical manifestation that property glomerulonephritis be take hematuria, edema,proteinuria,hypertension.Human liquid's metabolism, relies on the logical of lung qi to adjust, the transferring of temper, and opening of kidney qi is entire, thereby makes three warmers bring into play the duty that it is certainly shown disrespect on.Ailment said due to cold or exposure, water are wet in order to experience for the primary disease cause of disease, noxious dampness, damp and hot heresy, invasion and attack flesh table, and internal injury is in lung, impairment of dispersing and descending function of the lung; Or in be attributed to spleen, spleen loses transporting; Under injure kidney, kidney loses folding, disturbance in water passage, and be edema.In the acute nephritis edema stage, inhibited pulmonary QI, at lung, spleen, be take as main in main diseases position.If hematuria is obvious, how by damp-heat accumulation bladder, injury of blood collaterals by heat, due to venation is impaired.If intenseness of heat wind symptom, disturbs sun clearly on wind-fire, there is dizziness headache, even the evil card of violating conscience such as convulsions, coma.Spleen-QI failing to rise up, deficiency of kidney-QI, essence is closed not solid, and, there is albuminuria in separating clear and excreting turbid dereliction of duty.Therefore the sick position of primary disease is dirty at lung, spleen, kidney three, syndrome develop be from table and, by the part of the body cavity above the diaphragm housing the heart and lungs, in Jiao and reach the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, from real, to simulataneous insufficiency and excessive, develop.With the passing of time, feelings will is not smooth for stagnation of liver-QI, the liver failing to maintain the normal flow of QI, and send out primary disease.

clinical manifestation:sighing frequently, abdominal distention very.Onset is more anxious, and state of an illness weight is not etc.Most of patients has clear and definite streptococcal infection history, as upper respiratory tract infection, pharyngitis, tonsillitis and skin infection etc.Sudden onset, onset symptoms mostly is edema and hematuria.1, edema: the lighter only plays blepharoedema morning, and complexion is paler, is " nephritis face ".Severe one is prolonged and whole body, and finger pressure skin can be without significant depressions, and body weight also increases thereupon.2, hypertension: see 80% case, mostly be light moderate hypertension, diastolic pressure is less than 14kpa.The hypertension of acute nephritis mostly is a property crossed, and generation reason is mainly water, sodium retention makes due to blood volume expansion.3, urine is abnormal: 1. oliguria: most of patients onset has oliguria often, as every day urine amount be less than 500ml person, can there is slight azotemia.2. hematuria: see all acute nephritis patients, can be gross hematuria, or muddy coffee-like, general persistence is not long, transfers microscopic hematuria to.3. albuminuria: most of patients all has 4. whole body performance of albuminuria in various degree: tired, lumbago, anorexia, feel sick, vomiting, the person of being in a bad way can have headache, dizziness, drowsiness, blurred vision etc.Body of the tongue is light red, white and thin fur, wiry and frequent pulse.

its technical scheme is:get Pericarpium Citri Reticulatae Viride 9 weight portions, Flos Caryophylli 6 weight portions, Fructus Akebiae 6 weight portions, Fructus Anisi Stellati 9 weight portions, Folium Et Cacumen Murrayae 9 weight portions, Aspongopus 3 weight portions, Semen Canavaliae 6 weight portions, Radix Inulae 3 weight portions, Fructus Toosendan 1 weight portion, Semen Caesalpiniae 3 weight portions, the Radix Linderae 6 weight portions, Radix Et Rhizoma Nardostachyos 3 weight portions, Ambra Grisea 3 weight portions, Radix Curcumae 9 weight portions, Radix et Caulis Opuntiae Dillenii 3 weight portions, Herba Agrimoniae 3 weight portions, Pseudobulbus Bletillae (Rhizoma Bletillae) 6 weight portions, Terra Flava Usta 3 weight portions, Crinis Carbonisatus 3 weight portions, Radix Rumicis Japonici 1 weight portion, Ophicalcitum 6 weight portions, Radix Boehmeriae 3 weight portions, Radix Rubiae 3 weight portions, Herba Salviae Plebeiae 6 weight portions, Flos althaeae roseae 6 weight portions, Herba Ecliptae 6 weight portions, Pericarpium Arecae 6 weight portions and Radix Glycyrrhizae 9 weight portions, above 28 taste Chinese medicines are put into 1500 ml waters, soak 35 minutes, then slow fire is fried 30 minutes, boil medicine altogether 360 milliliters of liquid of filter and remove residue, fried medicinal liquid is the Chinese medicine for the treatment of abdominal distension type acute glomerulonephritis.

the advantage of this invention is:we's 28 taste Chinese medicines, all can buy in pharmacy, make simply, and the herb liquid toxic and side effects of making is little, short treating period, and cure rate is high.Monarch, just right.In the time of application Chinese medicine, untoward reaction, anaphylaxis and the toxic reaction of having avoided Western medicine to cause.Pericarpium Citri Reticulatae Viride, Flos Caryophylli, Fructus Akebiae, Fructus Anisi Stellati, Folium Et Cacumen Murrayae, Aspongopus, Semen Canavaliae, Radix Inulae, Fructus Toosendan, Semen Caesalpiniae, the Radix Linderae, Radix Et Rhizoma Nardostachyos, Ambra Grisea, Radix Curcumae, above 14 taste medical instruments have that soothing the liver dispelling the stagnated QI, loose long-pendingization are stagnant, soothing liver-QI stomach function regulating, solution be tired of quench the thirst, cold expelling, the therapeutic method to keep the adverse QI flowing downwards, kidney tonifying complement, promoting the circulation of QI to relieve pain effect.In the process for the treatment of abdominal distension type acute glomerulonephritis, play primary treatment effect, therefore be monarch drug.Radix et Caulis Opuntiae Dillenii, Herba Agrimoniae, Pseudobulbus Bletillae (Rhizoma Bletillae), Terra Flava Usta, Crinis Carbonisatus, Radix Rumicis Japonici, Ophicalcitum, Radix Boehmeriae, Radix Rubiae, Herba Salviae Plebeiae, Flos althaeae roseae, Herba Ecliptae, above 12 taste medical instruments have the effect of promoting blood circulation and hemostasis, spleen invigorating removing food stagnancy, promoting blood circulation and detumescence, eliminating stasis to stop pain, dispersing cold for relieving pain, stomach function regulating preventing or arresting vomiting, in the process for the treatment of abdominal distension type acute glomerulonephritis, can bring into play therapeutical effect by auxiliary principal agent, therefore be ministerial drug.Pericarpium Arecae: pungent, tepor.Enter spleen, stomach, large and small intestinal four warps.Therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, inducing diuresis to remove edema.The all medicines of the energy rate focus of going directly, therefore be adjuvant drug.Radix Glycyrrhizae: sweet, flat.Enter 12 warps.Spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.Can entangle the bias of all medicines, can alleviate again the toxicity of all medicines, therefore for making medicine.Pericarpium Citri Reticulatae Viride, Flos Caryophylli, Fructus Akebiae, Fructus Anisi Stellati, Folium Et Cacumen Murrayae, Aspongopus, Semen Canavaliae, Radix Inulae, Fructus Toosendan, Semen Caesalpiniae, the Radix Linderae, Radix Et Rhizoma Nardostachyos, Ambra Grisea, Radix Curcumae, Radix et Caulis Opuntiae Dillenii, Herba Agrimoniae, Pseudobulbus Bletillae (Rhizoma Bletillae), Terra Flava Usta, Crinis Carbonisatus, Radix Rumicis Japonici, Ophicalcitum, Radix Boehmeriae, Radix Rubiae, Herba Salviae Plebeiae, Flos althaeae roseae, Herba Ecliptae, Pericarpium Arecae, Radix Glycyrrhizae, this 28 taste medicine compatibility application, jointly play soothing the liver dispelling the stagnated QI, loose long-pendingization is stagnant, warming the kidney tonifying YANG, soothing liver-QI stomach function regulating, inducing diuresis for treating stranguria syndrome, cold expelling, warming middle-JIAO to stop diarrhea, the therapeutic method to keep the adverse QI flowing downwards, kidney tonifying complement, promoting the circulation of QI to relieve pain, promoting blood circulation and hemostasis, spleen invigorating removing food stagnancy, promoting blood circulation and detumescence, eliminating stasis to stop pain, the effect of stomach function regulating preventing or arresting vomiting.Monarch, compatibility is proper, is the optimum formula for the treatment of abdominal distension type acute glomerulonephritis.Pericarpium Citri Reticulatae Viride: bitter, pungent, warm.Enter liver, gallbladder meridian.Soothing the liver dispelling the stagnated QI, loose long-pendingization is stagnant.Flos Caryophylli: pungent, temperature.Enter spleen, stomach, kidney channel.Warming middle-JIAO to send down the adverse QI, warming the kidney tonifying YANG, promoting the circulation of QI to relieve pain, consciousness and resuscitation restoring, wards off dirty parasite killing.Fructus Akebiae: sweet, cold.Enter liver, stomach warp.Soothing liver-QI stomach function regulating, promoting blood circulation and stopping pain, inducing diuresis for treating stranguria syndrome, separates tired quenching the thirst.Fructus Anisi Stellati: acrid, sweet, warm.Enter liver,kidney,spleen, stomach warp.Warming spleen and stomach for dispelling cold, promoting the circulation of QI to relieve pain, warming and recuperating the kidney-YANG, wards off evil dirt eliminating.Folium Et Cacumen Murrayae: pungent, bitter, temperature.Enter the heart, liver, lung meridian.Promoting the circulation of QI to relieve pain, promoting blood circulation to remove blood stasis, expelling wind and removing dampness, hard masses softening and resolving.Aspongopus: salty, sweet, temperature, nontoxic.Enter liver,spleen,kidney warp.Promoting the circulation of QI to relieve pain, warming the kidney to invigorate YANG, warming middle-JIAO to stop diarrhea.Semen Canavaliae: sweet, flat, nontoxic.Enter spleen, stomach, large intestine, kidney channel.Warming the middle warmer and descending qi, kidney tonifying complement, eliminating phlegm and relieving asthma, promoting the circulation of QI to relieve pain.Radix Inulae: pungent, bitter, temperature.Enter lung, liver, spleen channel.Invigorating the spleen and regulating the stomach, promoting the circulation of QI to relieve pain, get rid of evils and control algid malaria, peace ascarifuge.Fructus Toosendan: hardship, cold, slightly poisonous.Enter liver, stomach, small intestinal, urinary bladder channel.Removing dampness and killing parasites, promoting the circulation of QI to relieve pain, clearing heat, purging intense-heat.Semen Caesalpiniae: pungent, temperature.Enter lung, large intestine channel.Promoting the circulation of QI to relieve pain, preventing the attack (or recurrence) of malaria, only quenches one's thirst.The Radix Linderae: pungent, temperature.Enter lung, spleen, kidney, urinary bladder channel.Promoting the circulation of QI to relieve pain, warming kidney for dispelling cold.Radix Et Rhizoma Nardostachyos: acrid, sweet, warm.Enter spleen, stomach warp.Promoting the circulation of QI to relieve pain, activating spleen and strengthening stomach, removing dampness is drawn out pus by applying a plaster to the affected part.Ambra Grisea: sweet, sour, gas raw meat, tepor.Enter the heart, lung, liver, kidney channel.Promoting flow of QI and blood, relieving stranguria by diuresis, relieving cough and asthma, promotes the production of body fluid and is full of cheek, wards off dirty removing toxic substances.Radix Curcumae: pungent, bitter, cold.Enter the heart, lung, liver, gallbladder meridian.Circulation of qi promoting blood stasis dispelling, heart fire-clearing upset-relieving, cooling blood for hemostasis.Radix et Caulis Opuntiae Dillenii: hardship, cold.Enter the heart, lung, stomach warp.Promoting flow of QI and blood, heat-clearing and toxic substances removing, evacuation of pus granulation promoting, cooling blood for hemostasis, clearing away lung-heat to relieve cough.Herba Agrimoniae: bitter, puckery, micro-sweet, flat.Enter lung, liver, spleen, large intestine channel.Astringing to arrest bleeding, tonify deficiency dysentery relieving, parasite killing removing toxic substances, preventing the attack (or recurrence) of malaria, promoting blood circulation and detumescence.Pseudobulbus Bletillae (Rhizoma Bletillae): bitter, sweet, puckery, be slightly cold.Enter lung, liver, stomach warp.Astringing to arrest bleeding, swollen clearly granulation promoting, parasite killing sore.Terra Flava Usta: pungent, tepor.Enter spleen, stomach, Liver Channel.Warming middle-JIAO hemostasis, stomach function regulating preventing or arresting vomiting, warming the spleen astringing intestine to stop diarrhea.Crinis Carbonisatus: hardship, flat.Enter liver, stomach warp.Hemostasis dissipating blood stasis, nourishing YIN diuresis, promoting tissue regeneration and ulcer healing.Radix Rumicis Japonici: hardship, cold, mild toxicity.Enter spleen, liver, large intestine, urinary bladder channel.Cooling blood for hemostasis, parasite killing are treated tinea, expelling pathogenic heat to loosen the bowels.Ophicalcitum: sour, puckery, flat.Enter Liver Channel.Astringing to arrest bleeding, hemostasis by removing blood stasis.Radix Boehmeriae: sweet, cold.Enter the heart, Liver Channel.Cooling blood for hemostasis, heat-clearing and toxic substances removing, clearing heat and preventing abortion, clearing away heat and promoting diuresis.Radix Rubiae: bitter, salty, sour, cold.Enter liver, the heart, spleen, stomach, lung meridian.Cooling blood for hemostasis, blood circulation promoting and blood stasis dispelling, dispelling wind dredging collateral, heat clearing away jaundice eliminating, eliminating phlegm and stopping cough.Herba Salviae Plebeiae: pungent, bitter, cool.Enter the heart, liver, kidney channel.Cooling blood for hemostasis, inducing diuresis to remove edema, removing toxic substances parasite killing.Flos althaeae roseae: sweet, salty, cold, nontoxic.Enter spleen, stomach, kidney channel.Promoting blood circulation and hemostasis, clearing away heat-damp and promoting diuresis, moistening dryness for relaxing bowels, detoxicating and resolving stagnation of pathogens.Herba Ecliptae: sweet, sour, cool.Enter liver, kidney, stomach, large and small intestinal warp.Cooling blood for hemostasis, yin nourishing black hair, removing dampness to relieve itching.Pericarpium Arecae: pungent, tepor.Enter spleen, stomach, large and small intestinal four warps.Therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, inducing diuresis to remove edema.Radix Glycyrrhizae: sweet, flat.Enter 12 warps.Spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.

the specific embodiment

Get Pericarpium Citri Reticulatae Viride 9g, Flos Caryophylli 6g, Fructus Akebiae 6g, Fructus Anisi Stellati 9g, Folium Et Cacumen Murrayae 9g, Aspongopus 3g, Semen Canavaliae 6g, Radix Inulae 3g, Fructus Toosendan 1g, Semen Caesalpiniae 3g, Radix Linderae 6g, Radix Et Rhizoma Nardostachyos 3g, Ambra Grisea 3g, Radix Curcumae 9g, Radix et Caulis Opuntiae Dillenii 3g, Herba Agrimoniae 3g, Pseudobulbus Bletillae (Rhizoma Bletillae) 6g, Terra Flava Usta 3g, Crinis Carbonisatus 3g, Radix Rumicis Japonici 1g, Ophicalcitum 6g, Radix Boehmeriae 3g, Radix Rubiae 3g, Herba Salviae Plebeiae 6g, Flos althaeae roseae 6g, Herba Ecliptae 6g, Pericarpium Arecae 6g and Radix Glycyrrhizae 9g, above 28 taste medicines are put into 1500 ml waters together, soak 35 minutes, then slow fire is fried 30 minutes, filter and remove residue, fried medicinal liquid is the Chinese medicine for the treatment of abdominal distension type acute glomerulonephritis.Boil medicine altogether 360 milliliters of liquid, when the client need treatment of abdominal distension type acute glomerulonephritis, making fluid temperature is 36 ℃, each 120 milliliters, oral, every day three times, within 2nd, be a course for the treatment of, if symptom is still deposited, then took for second course for the treatment of, so that recovery from illness.

In 366 routine abdominal distension type acute glomerulonephritis patients, male's 175 examples, account for 47.81%; Women's 191 examples, account for 52.19%.Women is more than male.

The range of age of table one, 366 routine abdominal distension type acute glomerulonephritis patients

Age (year)	18～25	26～35	36～55	56～66
					Number of cases	13	215	131	7
Percentage ratio	3.55%	58.75%	35.79%	1.91%

Table two, 366 routine abdominal distension type acute glomerulonephritis patient curative effect tables

Curative effect	Cure	Take a turn for the better	Invalid
				Number of cases	361	5	Nothing
Percentage ratio	98.63%	1.37%	Nothing

Table three, 366 routine abdominal distension type acute glomerulonephritis patients show the course for the treatment of

Treatment natural law	3～5	6～10	11～16	17～27
					Number of cases	12	251	95	8
Percentage ratio	3.28%	68.58%	25.96%	2.18%

Information slip before and after table four, 366 routine abdominal distension type acute glomerulonephritis patient treatments

Claims (1)

1. a Chinese medicinal preparation method for the treatment of abdominal distension type acute glomerulonephritis, it is characterized in that: get 9 grams, Pericarpium Citri Reticulatae Viride, 6 grams of Flos Caryophyllis, 6 grams of Fructus Akebiaes, 9 grams of Fructus Anisi Stellatis, 9 grams of Folium Et Cacumen Murrayae, 3 grams of Aspongopuss, 6 grams of Semen Canavaliaes, 3 grams of Radix Inulaes, 1 gram of Fructus Toosendan, 3 grams of Semen Caesalpiniae, 6 grams of the Radixs Linderae, 3 grams of Radix Et Rhizoma Nardostachyos, 3 grams of Ambra Griseas, 9 grams of Radix Curcumaes, 3 grams of Radix et Caulis Opuntiae Dilleniis, 3 grams of Herba Agrimoniaes, 6 grams of Pseudobulbus Bletillae (Rhizoma Bletillae), 3 grams of Terra Flava Ustas, 3 grams of Crinis Carbonisatus, 1 gram, Radix Rumicis Japonici, 6 grams of Ophicalcitums, 3 grams of Radix Boehmeriaes, 3 grams of Radix Rubiae, 6 grams of Herba Salviae Plebeiaes, 6 grams of Flos althaeae roseaes, 6 grams of Herba Ecliptaes, 9 grams, 6 grams of Pericarpium Arecae and Radix Glycyrrhizae, above 28 taste Chinese medicines are put into 1500 ml waters, soak 35 minutes, then slow fire is fried 30 minutes, boil medicine altogether 360 milliliters of liquid of filter and remove residue, fried medicinal liquid is the Chinese medicine for the treatment of abdominal distension type acute glomerulonephritis.