CN102805853B - Preparation method of traditional Chinese medicine for treating proteinuria type acute glomerulonephritis - Google Patents
Preparation method of traditional Chinese medicine for treating proteinuria type acute glomerulonephritis Download PDFInfo
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Abstract
The invention relates to a preparation method of a traditional Chinese medicine for treating proteinuria type acute glomerulonephritis, and belongs to the technical field of traditional Chinese medicine preparation methods. At present, penicillin is generally used for treating the proteinuria type acute glomerulonephritis, but is easy to lead to allergic reaction of patients and especially lead to allergic shock of the patients, and can threat to life of the patients if the patients are not rescued in time. The technical scheme includes that longan pulp, bighead atractylodes rhizome, American ginseng, lotus seeds, root of hairy asiabell, sharpleaf galangal fruit, the root of membranous milk vetch, solomon's seal, polished round-grained rice, dried ginger, herb cistanche, actinolite, the bark of eucommia, the tuber of multiflower knotweed, tortoise plastron, flatstem milk vetch seed, earthworms, snake slough, antelope's horns, concha mauritiae, centipede, dung beetle and liquorice are placed into water for soaking and then are decocted by slow fire, and decoction is the traditional Chinese medicine for treating the proteinuria type acute glomerulonephritis. The preparation method has the advantages that the traditional Chinese medicine is easy to prepare, short in treatment course and high in curative ratio; the proteinuria type acute glomerulonephritis is treated to the point by means of assistant and guide; and adverse reaction, anaphylactic reaction and toxic reaction caused by western medicines are avoided in application of the prepared traditional Chinese medicine.
Description
Technical field
The present invention relates to the Chinese medicinal preparation method technical field, more specifically a kind of Chinese medicinal preparation method for the treatment of the Proteinuria Type acute glomerulonephritis.
Background technology
Treatment Proteinuria Type acute glomerulonephritis, generally employing at present:
1, penicillin: allergy easily occurs in this product, anaphylactic shock (the most dangerous anaphylactic shock particularly, can occur in and do tuerculoderma at that time, only a few can occur in the continuous use process, Delayed Hypersensitivity shock), as rescued not in time, can critical life, therefore all will improve protection before, during and after medication, so as to avoid an accident.Attention: before application, must ask and have or not clearly anaphylactic disease, with having or not the allergy such as erythra, heating to occur after penicillin, must first do penicillin skin test.
2, amoxicillin: accidental erythra, oral can have nauseating, epigastric discomfort, diarrhoea etc. after a large amount of; Pseudomembranous colitis.
3, carbenicillin: various types of allergy can occur.May cause neural poison reaction, pulmonary edema after heavy dose of administration, may occur during medication that the transience transaminase raises and granulocytopenia.
4, reserpine: nasal obstruction, gastric acid secretion increase, times of defecation increases and aroused in interest slack-off etc., even long-term extensive application can occur that apathetic expression, drowsiness, spirit depressing cause extrapyramidal symptoms, the performance muscular tremor.1. to activeness Peptic Ulcers and dysthymia person's forbidding; 2. reserpine can enter fetal tissue by Placenta Hominis, if the antenatal application of anemia of pregnant woman can cause neonate nasal obstruction, respiratory tract obstruction, should need not as far as possible.
5, hydrochlorothiazide: the low blood chlorine of 1. hypokalemia, and normal companion, hypomagnesemia, hypokalemia can bring out hepatic coma and Folium Digitalis Purpureae institute proarrhythmia, needs timely kalium replenishment or add to stay the potassium diuretic; 2. hyperglycemia reduces carbohydrate tolerance; 3. hyperuricemia, can bring out or increase the weight of symptom to the goat image; 4. azotemia, because reducing glomerular filtration rate, increase the weight of azotemia and renal function further worsened the renal insufficiency patient, and this product diuretic effect is poor, therefore the renal failure patient is cautious use of or forbids; 5. ammonirrhea reduces, and may the H+ secretion be reduced because suppressing carbonic anhydrase, and the ammonia secretion also reduces.During hepatic disfunction, can bring out hepatic coma; 6. parathyroid gland effect: long-term taking can cause hypercalcemia, low serum p disease and parathyroid hyperplasia; 7. other: skin erythema, photoallergic dermatitis, pancreatitis, intrahepatic cholestasis, bone marrow depression, especially thrombocytopenia can cause the announcements that all appear in the newspapers such as purpura, neutrophilic granulocyte minimizing, hemolytic anemia of newborn, the serum antinuclear antibody positive.
6, bendazol: headache, hyperhidrosis, heating sense are arranged.
7, captopril: important side effect is Toxicity of Kidney and granulocytopenia, is secondly erythra, dysgeusia and cough.Heavy dose can cause hemodynamic change, symptomatic hypotension etc.
Summary of the invention
For overcoming above-mentioned shortcoming, the objective of the invention is to invent a kind of Chinese medicinal preparation method for the treatment of the Proteinuria Type acute glomerulonephritis.Acute glomerulonephritis, be called for short acute nephritis, is one group of common glomerule illness.Onset is anxious, and take hematuria, oliguria, albuminuria, edema and hypertension etc. is its Clinical symptoms.Acute nephritis can be because of due to Different types of etiopathogenises, and wherein modal is post-streptococcal infection nephritis, and other causes of disease still have antibacterial (as staphylococcus), virus (as hepatitis B virus), protozoon (as plasmodium) etc.Primary disease belongs to " edema due to wind pathogen ", the category of " YANG edema " and " hematuria " in Chinese medicine " edema ".
etiology and pathogenesis: anxiousit is main clinical manifestation that the property glomerulonephritis be take hematuria, edema,proteinuria,hypertension.Human liquid's metabolism, rely on the logical of lung qi to adjust, the transferring of temper, and opening of kidney qi is entire, thereby makes three warmers bring into play the duty that it is certainly shown disrespect on.Ailment said due to cold or exposure, water are wet in order to experience for the primary disease cause of disease, noxious dampness, damp and hot heresy, invasion and attack flesh table, and internal injury is in lung, impairment of dispersing and descending function of the lung; Or in be attributed to spleen, spleen loses transporting; Under injure kidney, kidney loses folding, disturbance in water passage, and be edema.In the acute nephritis edema stage, inhibited pulmonary QI, at lung, spleen, be take as main in the main diseases position.If hematuria is obvious, how by the damp-heat accumulation bladder, injury of blood collaterals by heat, due to venation is impaired.If the intenseness of heat wind symptom, disturb sun clearly on wind-fire, the evil card of violating conscience such as convulsions, coma dizziness headache appears, even.Spleen-QI failing to rise up, deficiency of kidney-QI, essence is closed not solid, and albuminuria, appear in the separating clear and excreting turbid dereliction of duty.Therefore the sick position of primary disease is dirty at lung, spleen, kidney three, syndrome develop be from table and, by the part of the body cavity above the diaphragm housing the heart and lungs, in Jiao and reach the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, from real, to simulataneous insufficiency and excessive, develop.Due to spleen-QI failing to rise up, deficiency of kidney-QI, essence is closed not solid, and the separating clear and excreting turbid dereliction of duty, send out primary disease.
clinical manifestation:albuminuria is main.Onset is more anxious, and state of an illness weight does not wait.Most of patients has clear and definite streptococcal infection history, as upper respiratory tract infection, pharyngitis, tonsillitis and skin infection etc.Sudden onset, onset symptoms mostly is edema and hematuria.1, edema: the lighter only plays blepharoedema morning, and complexion is paler, is " nephritis face ".Severe one is prolonged and whole body, and finger pressure skin can be without significant depressions, and body weight also increases thereupon.2, hypertension: see 80% case, mostly be light moderate hypertension, diastolic pressure is less than 14kpa.The hypertension of acute nephritis mostly is a property crossed, and the generation reason is mainly water, sodium retention makes due to the blood volume expansion.3, urine is abnormal: 1. oliguria: the most of patients onset has oliguria often, as every day the urine amount be less than 500ml person, slight azotemia can appear.2. hematuria: see all acute nephritis patients, can be gross hematuria, or muddy coffee-like, general persistence is not long, transfers microscopic hematuria to.3. whole body performance: tired, lumbago, anorexia, feel sick, vomiting, the person of being in a bad way can have headache, dizziness, drowsiness, blurred vision etc.Pale tongue, tongue is white, deep-thready pulse.
its technical scheme is:get Arillus Longan 6 weight portions, the Rhizoma Atractylodis Macrocephalae 6 weight portions, Radix Panacis Quinquefolii 3 weight portions, Semen Nelumbinis 6 weight portions, Radix Codonopsis 6 weight portions, Fructus Alpiniae Oxyphyllae 3 weight portions, the Radix Astragali 3 weight portions, Rhizoma Polygonati 6 weight portions, Semen oryzae sativae 9 weight portions, Rhizoma Zingiberis 3 weight portions, Herba Cistanches 3 weight portions, Actinolitum 6 weight portions, the Cortex Eucommiae 9 weight portions, Radix Polygoni Multiflori 9 weight portions, Carapax et Plastrum Testudinis 3 weight portions, Semen Astragali Complanati 6 weight portions, Lumbricus 6 weight portions, Periostracum Serpentis 3 weight portions, Cornu Saigae Tataricae 0.5 weight portion, Concha Erosariae seu Cypraeae 6 weight portions, Scolopendra 1 weight portion, Catharsii molossi 1 weight portion and Radix Glycyrrhizae 9 weight portions, above 23 flavor Chinese medicines are put into to 1500 ml waters, soak 35 minutes, then slow fire is fried 30 minutes, boil medicine altogether 360 milliliters of liquid of filter and remove residue, fried medicinal liquid is the Chinese medicine for the treatment of Proteinuria Type acute glomerulonephritis.
the advantage of this invention is:we's 23 flavor Chinese medicines, all can buy in pharmacy, makes simply, and the herb liquid toxic and side effects of making is little, short treating period, and cure rate is high.Monarch, just right.In the time of application Chinese medicine, untoward reaction, anaphylaxis and the toxic reaction of having avoided Western medicine to cause.
Arillus Longan, the Rhizoma Atractylodis Macrocephalae, Radix Panacis Quinquefolii, Semen Nelumbinis, Radix Codonopsis, Fructus Alpiniae Oxyphyllae, the Radix Astragali, Rhizoma Polygonati, Semen oryzae sativae, Rhizoma Zingiberis, Herba Cistanches, Actinolitum, the Cortex Eucommiae, Radix Polygoni Multiflori, Carapax et Plastrum Testudinis, Semen Astragali Complanati, above 16 flavor medical instruments have QI invigorating emergency treatment of collapse, strengthening the spleen and nourishing the stomach, warm spleen cold expelling, invigorating the spleen and replenishing QI, invigorating the liver and kidney, benefit purify the blood, nourishing YIN for suppressing the hyperactive YANG, replenishing YIN and removing heat, the strong muscle of the kidney invigorating, the kidney invigorating benefit heart, the effect of nourishing the liver to improve visual acuity.In the process for the treatment of Proteinuria Type acute glomerulonephritis, play the primary treatment effect, therefore be monarch drug.
Lumbricus, Periostracum Serpentis, Cornu Saigae Tataricae, Concha Erosariae seu Cypraeae, Scolopendra, above 5 flavor medical instruments have heat-clearing and toxic substances removing, relieving cough and asthma, tonneau urine, removing toxic substances and promoting subsidence of swelling, removing pathogenic heat from blood and toxic substance from the body, the effect of liver heat removing and eyesight improving.In the process for the treatment of Proteinuria Type acute glomerulonephritis, can assist principal agent performance therapeutical effect, therefore be ministerial drug.
Catharsii molossi: salty, cold, poisonous.Enter stomach, large intestine, liver three warps.Clearing phlegm for calming endogenous wind, heat-clearing and toxic substances removing, drastically removing blood stasis and resolving static blood.The all medicines of the energy rate focus of going directly, therefore be adjuvant drug.
Radix Glycyrrhizae: sweet, flat.Enter 12 warps.The spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.Can entangle the bias of all medicines, can alleviate again the toxicity of all medicines, therefore for making medicine.
Arillus Longan, the Rhizoma Atractylodis Macrocephalae, Radix Panacis Quinquefolii, Semen Nelumbinis, Radix Codonopsis, Fructus Alpiniae Oxyphyllae, the Radix Astragali, Rhizoma Polygonati, Semen oryzae sativae, Rhizoma Zingiberis, Herba Cistanches, Actinolitum, the Cortex Eucommiae, Radix Polygoni Multiflori, Carapax et Plastrum Testudinis, Semen Astragali Complanati, Lumbricus, Periostracum Serpentis, Cornu Saigae Tataricae, Concha Erosariae seu Cypraeae, Scolopendra, Catharsii molossi, Radix Glycyrrhizae, this 23 flavor medicine compatibility application, jointly play QI invigorating emergency treatment of collapse, strengthening the spleen and nourishing the stomach, warm spleen cold expelling, invigorating the spleen and replenishing QI, invigorating the liver and kidney, benefit purify the blood, nourishing YIN for suppressing the hyperactive YANG, replenishing YIN and removing heat, the strong muscle of the kidney invigorating, the kidney invigorating benefit heart, nourishing the liver to improve visual acuity, heat-clearing and toxic substances removing, relieving cough and asthma, tonneau urine, removing toxic substances and promoting subsidence of swelling, the effect of removing pathogenic heat from blood and toxic substance from the body.Monarch, compatibility is proper, is the optimum formula for the treatment of Proteinuria Type acute glomerulonephritis.
Arillus Longan: sweet, warm.Enter the heart, spleen two warps.Invigorating the heart and spleen, nourishing blood to tranquillize the mind, nourishing the lung to arrest cough.
The Rhizoma Atractylodis Macrocephalae: bitter, sweet, temperature.Enter spleen, stomach two warps.Air making-up and spleen enlivening, drying dampness to eliminate phlegm, diuretic detumescent, expelling wind and cold, strengthening superficial resistance to stop perspiration, QI invigorating are antiabortive.
Radix Panacis Quinquefolii: hot, sweet, bitter, cold.Enter the heart, lung, stomach, kidney, the large intestine Five Classics.QI invigorating tonifying YIN, clearing away heat and promoting production of body fluid, clearing away heat to stop bleeding.
Semen Nelumbinis: sweet, puckery, flat.Enter the heart, spleen, kidney three warps.Spleen reinforcing antidiarrheal, kidney tonifying are only lost, tranquilizing by nourishing the heart.
Radix Codonopsis: sweet, flat.Enter lung, spleen two warps.Replenishing QI to invigorate the spleen, supplementing QI for promoting the production of body fluid, QI invigorating heat extraction.
Fructus Alpiniae Oxyphyllae: suffering, temperature.Enter spleen, stomach two warps.Warm spleen cold expelling, the kidney warming tonify deficiency.
The Radix Astragali: sweet, tepor, nontoxic.Enter lung, spleen two warps.Tonifying Qi and lifting yang, hemostasis by invigorating QI, QI invigorating row are stagnant, blood stasis removing eliminating stagnation, benefiting QI for strengthening the superficies, QI invigorating tonifying YIN, inducing diuresis to remove edema, warming the interior cold expelling, pus expelling by strengthening vital QI granulation promoting, strong body constitution, life lengthening.
Rhizoma Polygonati: sweet, flat, nontoxic.Enter spleen, lung, kidney three warps.Control deficiency of lung-YIN cough, control pulmonary tuberculosis hemoptysis, beneficial able-bodied muscles and bones, control interior-heat and quench one's thirst, control weakness of the spleen and stomach.
Semen oryzae sativae: sweet, flat.Enter spleen, stomach two warps.Invigorating the spleen and replenishing QI, invigorating spleen to remove dampness.
Rhizoma Zingiberis: hot, hot.Enter spleen, stomach, lung three warps.Warming middle-JIAO by cold, recuperating depleted YANG is promoted blood circulation, the expectorant therapeutic method to keep the adverse QI flowing downwards, warming the lung to resolve fluid-retention, warming the meridian for stopping bleeding, control carbuncle from the beginning of.
Herba Cistanches: sweet, sour, salty, temperature.Enter kidney, large intestine, spleen, liver, the bladder Five Classics.Reinforcing the kidney and supporting YANG, loosening bowel to relieve constipation, deficiency and coldness diarrhea, hard masses softening and resolving.
Actinolitum: salty, tepor.Enter kidney channel.Warming the kidney to invigorate YANG.
The Cortex Eucommiae: sweet, micro-suffering, temperature.Enter liver, kidney two warps.Liver and kidney tonifying, strong muscles and bones, antiabortive hemostasis.
Radix Polygoni Multiflori: bitter, sweet, puckery, tepor.Enter liver, kidney channel.Invigorating the liver and kidney, benefit purify the blood, and skin ulcer is controlled in relieving constipation, preventing the attack (or recurrence) of malaria.
Carapax et Plastrum Testudinis: salty, sweet, flat.Enter liver, kidney two warps.Nourishing YIN for suppressing the hyperactive YANG, replenishing YIN and removing heat, the strong muscle of the kidney invigorating, the kidney invigorating benefit heart, only collapse to treat and leak, and removing food stagnancy is broken poly-, and eliminating carbuncle is controlled skin ulcer, preventing the attack (or recurrence) of malaria.
Semen Astragali Complanati: sweet, temperature.Enter the heart, liver, kidney three warps.Tonifying the kidney to consolidate the essence, nourishing the liver to improve visual acuity.
Lumbricus: salty, cold.Enter liver, spleen, lung three warps.Heat-clearing and toxic substances removing, suppressing the hyperactive liver to relieve the wind syndrome, relieving cough and asthma, relaxing muscles and tendons and activating QI and blood in the collateral, tonneau urine.
Periostracum Serpentis: sweet, salty, flat.Enter liver, spleen two warps.Expelling wind for relieving convulsion, removing nebula to improve visual acuity, removing toxic substances and promoting subsidence of swelling, parasite killing is treated tinea.
Cornu Saigae Tataricae: salty, cold.Enter liver, the heart two warps.Suppressing the hyperactive liver to relieve the wind syndrome, heat clearing away is relieving convulsion, removing pathogenic heat from blood and toxic substance from the body, loose blood removing toxic substances.
Concha Erosariae seu Cypraeae: salty, flat.Enter Liver Channel.The heat clearing away suppressing the hyperactive liver, liver heat removing and eyesight improving, suppressing the hyperactive liver is calmed the nerves.
Scolopendra: hot, warm, poisonous.Enter liver, the heart two warps.The endogenous wind stopping relieving convulsion, detoxicating and resolving stagnation of pathogens, dredge the meridian passage, Scolopendra walks to alter limit speed.
Catharsii molossi: salty, cold, poisonous.Enter stomach, large intestine, liver three warps.Clearing phlegm for calming endogenous wind, heat-clearing and toxic substances removing, drastically removing blood stasis and resolving static blood.
Radix Glycyrrhizae: sweet, flat.Enter 12 warps.The spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.
The specific embodiment
Get Arillus Longan 6g, Rhizoma Atractylodis Macrocephalae 6g, Radix Panacis Quinquefolii 3g, Semen Nelumbinis 6g, Radix Codonopsis 6g, Fructus Alpiniae Oxyphyllae 3g, Radix Astragali 3g, Rhizoma Polygonati 6g, Semen oryzae sativae 9g, Rhizoma Zingiberis 3g, Herba Cistanches 3g, Actinolitum 6g, Cortex Eucommiae 9g, Radix Polygoni Multiflori 9g, Carapax et Plastrum Testudinis 3g, Semen Astragali Complanati 6g, Lumbricus 6g, Periostracum Serpentis 3g, Cornu Saigae Tataricae 0.5g, Concha Erosariae seu Cypraeae 6g, Scolopendra 1g, Catharsii molossi 1g and Radix Glycyrrhizae 9g, above 23 flavor medicines are put into 1500 ml waters together, soak 35 minutes, then slow fire is fried 30 minutes, filter and remove residue, fried medicinal liquid is the Chinese medicine for the treatment of Proteinuria Type acute glomerulonephritis.Boil medicine altogether 360 milliliters of liquid, when the client need treatment of Proteinuria Type acute glomerulonephritis, making fluid temperature is 36 ℃, each 120 milliliters, oral, every day three times, within 2nd, be a course for the treatment of, if symptom is still deposited, then took for second course for the treatment of, so that recovery from illness.
In 295 routine Proteinuria Type acute glomerulonephritis patients, male's 172 examples, account for 58.31%; Women's 123 examples, account for 41.69%.The male is more than the women.
The range of age of table one, 295 routine Proteinuria Type acute glomerulonephritis patients
| Age (year) | 17～26 | 27～36 | 37～56 | 57～60 |
| Number of cases | 13 | 129 | 151 | 2 |
| Percentage ratio | 4.41% | 43.73% | 51.18% | 0.68% |
Table two, 295 routine Proteinuria Type acute glomerulonephritis patient curative effect tables
| Curative effect | Cure | Take a turn for the better | Invalid |
| Number of cases | 293 | 2 | Nothing |
| Percentage ratio | 99.32% | 0.68% | Nothing |
Table three, 295 routine Proteinuria Type acute glomerulonephritis patients show the course for the treatment of
| The treatment natural law | 3～5 | 6～9 | 10～14 | 15～25 |
| Number of cases | 9 | 208 | 75 | 3 |
| Percentage ratio | 3.05% | 70.51% | 25.42% | 1.02% |
Information slip before and after table four, 295 routine Proteinuria Type acute glomerulonephritis patient treatments
Claims (1)
1. a Chinese medicinal preparation method for the treatment of the Proteinuria Type acute glomerulonephritis, it is characterized in that: get Arillus Longan 6 grams, the Rhizoma Atractylodis Macrocephalae 6 grams, Radix Panacis Quinquefolii 3 grams, Semen Nelumbinis 6 grams, Radix Codonopsis 6 grams, Fructus Alpiniae Oxyphyllae 3 grams, the Radix Astragali 3 grams, Rhizoma Polygonati 6 grams, Semen oryzae sativae 9 grams, Rhizoma Zingiberis 3 grams, Herba Cistanches 3 grams, Actinolitum 6 grams, the Cortex Eucommiae 9 grams, Radix Polygoni Multiflori 9 grams, Carapax et Plastrum Testudinis 3 grams, Semen Astragali Complanati 6 grams, Lumbricus 6 grams, Periostracum Serpentis 3 grams, Cornu Saigae Tataricae 0.5 gram, Concha Erosariae seu Cypraeae 6 grams, Scolopendra 1 gram, Catharsii molossi 1 gram and Radix Glycyrrhizae 9 grams, above 23 flavor Chinese medicines are put into to 1500 ml waters, soak 35 minutes, then slow fire is fried 30 minutes, boil medicine altogether 360 milliliters of liquid of filter and remove residue, fried medicinal liquid is the Chinese medicine for the treatment of Proteinuria Type acute glomerulonephritis.
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| CN1489912A (en) * | 2002-10-15 | 2004-04-21 | 刘玉峰 | Tonifying kidney egg and processing method thereof |
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| CN1489912A (en) * | 2002-10-15 | 2004-04-21 | 刘玉峰 | Tonifying kidney egg and processing method thereof |
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| Title |
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| 自拟肾炎灵治疗急慢性肾炎297例;贺升效 等;《陕西中医学院学报》;19941030;第17卷(第04期);第19-20页 * |
| 贺升效 等.自拟肾炎灵治疗急慢性肾炎297例.《陕西中医学院学报》.1994,第17卷(第04期),第19-20页. |
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