CN104587130A - Traditional Chinese medicine composition for treating acute glomerulonephritis - Google Patents
Traditional Chinese medicine composition for treating acute glomerulonephritis Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating acute glomerulonephritis. The traditional Chinese medicine composition consists of euphorbia thymifolia, semen canavaliae, common russianthistle herbs, l.leontopodiodes, yellow bellflowers, fructus cnidii, endothelium corneum gigeriae galli, lotus seeds, cynanchum atratum, curculigo orchioides, Japanese ginseng, gynostemma pentaphyllum, lxeris chinensis (thumb) nakai, cistanche deserticola, rhizoma cimicifugae, oriental blueberry leaves, dryopteris bissetiana, raspberries, cyperus rotundus and lignum sappan. According to the traditional Chinese medicine composition, all the traditional Chinese medicine raw materials can be bought from traditional Chinese medicine pharmacies, and are dialectically combined according to the theory of traditional Chinese medicine to achieve the effects of promoting qi circulation for diuresis, nourishing yin, warming yang, strengthening spleen, nourishing blood, clearing heat and removing toxicity, and the traditional Chinese medicine composition has the advantages of extensive medicine source, low cost, remarkable therapeutic effects and less side effects, and has obvious therapeutic effects on acute glomerulonephritis.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition for the treatment of acute glomerulonephritis.
Background technology
Acute glomerulonephritis is called for short acute nephritis, acute nephritis is a kind of both sides kidney diffusivity glomerular epithelial cell caused owing to infecting rear allergy is main acute illness, the feature of primary disease is that onset is comparatively anxious, occurs the range of clinical performances such as hematuria, albuminuria, cylinderuria, edema, oliguria, hypertension after infection 1-3 week.
Acute nephritis is more common in child, after often betiding infection, common after especially infecting with Hemolytic streptococcus " nephritogenic strains "; Onset is anxious, the course of disease is short, and main manifestations is hematuria, albuminuria, oliguria, edema, hypertension and azotemia, and active treatment prognosis is better, and minority can develop into chronic nephritis.The kidney enlargement of acute nephritis, color is greyish white and smooth, therefore also known as " branny kidney ".Can there be petechia on surface, and tangent plane cortex medullary substance boundary is clearly demarcated, and cone is congested, glomerule gray point-like.Microscopy: most of acute glomerulonephritis patient is acute proliferative, diffuse lesion, glomerular endothelial cells hypertrophy, swelling, proliferation of mesangial cells causes blood capillary luminal stenosis, even inaccessible.Glomerular mesangium, blood capillary and blister cavities all have obvious neutrophilic granulocyte and monocyte infiltration, in blood capillary, blood coagulation phenomenon occur time serious.The epithelial side can seeing glomerular basement membrane under Electronic Speculum has hump shape deposit, sometimes also sees small SED.Immunofluorescence can see deposit, includes immunoglobulin.
Nephritis belongs to the traditional Chinese medical science " edema " category in motherland, and some cases " edema " is not obvious, and based on hematuria, then belongs to " hematuria " category in blood disorder.By the feature of acute nephritis edema, edema due to wind pathogen, YANG edema class can be belonged to, attack outside its morbidity and ailment said due to cold or exposure, fight mutually afterwards in edema due to wind pathogen, or eating and drinking without temperance, the wet dipping of water, or excess of sexual intercourse, the deficiency of YIN is evil excessive relevant, and above-mentioned paathogenic factor can be caused a disease separately, also can hold concurrently and mix as disease, but not from wind, wet, malicious three categories of etiologic factors, relate to lung, spleen, kidney three are dirty, when rheumatism poison heresy, to injure lung spleen kidney three dirty, makes lung lose logical tune, spleen loses and transfers, kidney loses folding, and three burnt water channels lose smooth, and functioning of bladder is had no right, and it is wet to cause water, invade in poison heresy, essence of water and grain runs off in a large number, and occurs clinical all diseases.The treatment of this disease is can not single and opinion, has both needed drug application to control symptom, and has needed again block the renal fibrosis of acute nephritis patient with effective active Chinese drug component material and recovered, and recovered the normal function of patient.The general course of disease for the treatment of nephritis is longer, while drug application treatment, also will note coordinating dietetic therapy and physical exercise therapy etc.
Summary of the invention
The object of the invention is to for the deficiencies in the prior art, carry out dialectical composition of prescription according to theory of Chinese medical science, provide the Chinese medicine composition of the treatment acute glomerulonephritis that a kind of medicine source is wide, cost is low, evident in efficacy, side effect is little.
The present invention is achieved through the following technical solutions:
A kind of Chinese medicine composition for the treatment of acute glomerulonephritis is made up of the raw material of following weight portion: Euphorbia thymifolia 6-10 part, Sword Jackbean Seed 1-5 part, Herba Salsolae Collinae 10-15 part, Herba Leontopodii Leontopodioidis 5-7 part, Tuberous Sword Fern 1-3 part, Fructus Cnidii 6-8 part, Endothelium Corneum Gigeriae Galli 2-4 part, Plumula Nelumbinis 3-5 part, Radix Cynanchi Atrati 5-8 part, Rhizoma Curculiginis 6-9 part, Rhizoma Panacis Japonici 5-15 part, Herb Gynostemmae Pentaphylli 2-5 part, Flos et Folium Lactucae elatae 6-8 part, Herba Cistanches 3-5 part, Rhizoma Cimicifugae 10-12 part, Folium Vaccinii Bracteati 6-9 part, Dryopteris bissetiaha (Bak) C. Chr-Nephrodium bisseianum Bak 5-10 part, Fructus Rubi 6-8 part, Rhizoma Cyperi 10-15 part, Lignum Sappan 5-9 part.
Preferably, a kind of Chinese medicine composition for the treatment of acute glomerulonephritis is made up of the raw material of following weight portion: Euphorbia thymifolia 8 parts, Sword Jackbean Seed 3 parts, Herba Salsolae Collinae 12 parts, Herba Leontopodii Leontopodioidis 6 parts, Tuberous Sword Fern 2 parts, Fructus Cnidii 7 parts, Endothelium Corneum Gigeriae Galli 3 parts, Plumula Nelumbinis 4 parts, Radix Cynanchi Atrati 6 parts, Rhizoma Curculiginis 8 parts, Rhizoma Panacis Japonici 10 parts, Herb Gynostemmae Pentaphylli 4 parts, Flos et Folium Lactucae elatae 7 parts, Herba Cistanches 4 parts, Rhizoma Cimicifugae 11 parts, Folium Vaccinii Bracteati 7 parts, Dryopteris bissetiaha (Bak) C. Chr-Nephrodium bisseianum Bak 8 parts, Fructus Rubi 7 parts, Rhizoma Cyperi 13 parts, Lignum Sappan 7 parts.
The pharmacology of each crude drug is as follows:
Euphorbia thymifolia: sour-puckery flavor, slightly cool in nature.Heat-clearing and toxic substances removing, sore is antipruritic.External treatment flies infections skin ulcer, pemphigus, rotten the first-born poison, skin pruritus, and treatment by oral administration of medicines malaria, dysentery, has loose bowels, eczema, acute mastitis, hemorrhoid.
Sword Jackbean Seed: sweet in the mouth is warm in nature, nontoxic.Return spleen, stomach, large intestine, kidney channel.Warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, only oh, kidney tonifying complement.For Deficiency and coldness of spleen and stomach, singultus, vomiting, abdominal distention, diarrhoea, suffers from a deficiency of the kidney, lumbago, defect flatulence pain, timid cold cold extremities, pale complexion, phlegm dyspnea.
Herba Salsolae Collinae: lightly seasoned, cool in nature.Return Liver Channel.Suppressing the hyperactive liver and subsiding YANG, loosening bowel to relieve constipation.For hypertension, how sick, dizzy, insomnia, dryness of the intestine constipation.
Herba Leontopodii Leontopodioidis: micro-hardship is cool.Clearing away heat and cooling blood, kidney tonifying diuretic.For acute and chronic edema, hematuria, stranguria with turbid discharge.
Tuberous Sword Fern: sweet, light is micro-puckery, cool.Enter liver, kidney, stomach, small intestine meridian.Clearing away heat-damp and promoting diuresis, peaceful lung cough-relieving, softening the hard mass removing food stagnancy.For cold, fever, cough, hemoptysis of pulmonary tuberculosis, dysentery, acute enteritis, infantile malnutrition, toxic indigestion, urinary system infection; Mastitis are controlled in external, lymphadenitis.
Fructus Cnidii: acrid in the mouth, hardship, warm in nature.Return kidney, spleen channel.Warming the kidney to activate YANG, dispel the wind,
dampness, parasite killing., rheumatic arthralgia, scabies eczema infertile for impotence in male, scrotum pruritus due to damp pathogen, woman's leukorrhagia pudendal pruritus, cold uterus.
Endothelium Corneum Gigeriae Galli: sweet in the mouth, property is put down.Return spleen, stomach, small intestinal, urinary bladder channel.Invigorating the stomach and promoting digestion, arresting seminal emission, treating stranguria fossil.Do not disappear for food stagnation, vomiting dysentery, infantile malnutrition, the enuresis, seminal emission, the puckery pain of stranguria caused by urinary stone, gallbladder-distention hypochondriac pain.
Plumula Nelumbinis: bitter in the mouth, cold in nature.GUIXIN, kidney channel.Clearing away heart-fire for tranquillization, restoring normal coordination between the heart and kidney, unsmoothing the sperm and stopping bleeding.For heat attacking the pericardium, unconsciousness and delirium, disarmony between the heart and kidney insomnia seminal emission, heat in blood is spitted blood.
Radix Cynanchi Atrati: bitter in the mouth, salty, cold in nature.Return lung, stomach, kidney channel.Clearing away heat and cooling blood, inducing diuresis for treating stranguria syndrome,
removing toxic substancestreat skin ulcer.For
pathogenic warmthwound battalion heating, fever due to yin deficiency, hectic fever due to YIN-deficiency consumptive fever, puerperal fever due to deficiency of blood, pyretic stranguria, stranguria with blood, swollen ulcer drug.
Rhizoma Curculiginis: the kidney warming sun is strong; Dispel cold-damp.Main sexual impotence cold sperm; Urinary incontinence; Coldness and pain in the epigastrium; Soreness of waist and knee joint; Muscles and bones is weak; Lower limb contracture; Climacteric syndrome.
Rhizoma Panacis Japonici: sweet in the mouth, micro-hardship, slightly warm in nature.Return lung, spleen, Liver Channel.Xu-tonic, eliminating phlegm and stopping cough, dissipating blood stasis stops blooding, reducing swelling and alleviating pain.For inappetence, cough due to consumptive disease, spitting of blood, spit blood, epistaxis, has blood in stool, hematuria, vicarious menstruation, metrorrhagia, traumatic hemorrhage, lump in the abdomen, blood stasis amenorrhea, and puerperal, stasis of blood the moon was suffered from abdominal pain, traumatic injury, rheumatic arthritis, carbuncle, hemorrhoid, venom.
Herb Gynostemmae Pentaphylli: bitter in the mouth, micro-sweet, cool in nature.Return lung, spleen, kidney channel.Replenishing QI to invigorate the spleen, preventing phlegm from forming and stopping coughing, heat-clearing and toxic substances removing.Body void is weak, nephrasthenia emission, leukopenia, hyperlipemia, viral hepatitis, chronic gastroenteritis, chronic tracheitis.
Flos et Folium Lactucae elatae: bitter in the mouth, cold in nature.Return lung, spleen channel.Heat-clearing and toxic substances removing, expelling wind and removing dampness.For sun stroke, stomachache, carbuncle and ulcer furuncle and phyma.
Herba Cistanches: sweet in the mouth, salty, warm in nature.Return kidney, large intestine channel.Kidney-replenishing, benefiting essence-blood, intestine moistening road.Main kidney yang deficiency, the sexual impotence of asthenia of essence and blood, seminal emission, nebulousurine, the frequent micturition heeltap, lumbago flaccidity of the lower limbs, tinnitus order flower, menstruation is spread out the phase, infertility, dryness of the intestine constipation.
Rhizoma Cimicifugae: acrid in the mouth, sweet, cold nature.Return lung, spleen, large intestine, stomach warp.Deliver rash, heat-clearing and toxic substances removing, ascending up spleen-Qi and Yang.For seasonal epidemic pathogens epidemic disease, headache cold and heat, laryngalgia, aphtha, macule is not saturating, sinking of QI of middle-JIAO, chronic diarrhea chronic dysentery, proctoptosis, and women is collapsed, band, and uterus drops, carbuncle sore tumefacting virus.
Folium Vaccinii Bracteati: sour in the mouth, puckery, property is put down.GUIXIN, spleen, kidney channel.Benefit the intestines and stomach, nourishing the liver and kidney.For deficiency of spleen-QI and stomach-QI, chronic diarrhea, few food, deficiency of the liver and kindey, waist knee joint is weak, early whitening of beard and hair.
Dryopteris bissetiaha (Bak) C. Chr-Nephrodium bisseianum Bak: pungent is bitter, cold.Return
lungwarp.Heat-clearing and toxic substances removing.For seasonal pathogen sense, partial heat person, heating is heavy, and aversion to cold is light, and headache, swallows red, pharyngeal swelling, xerostomia and thirsty, red tongue, white and thin fur, floating pulse person.
Fructus Rubi: sweet in the mouth, acid, warm in nature.Return liver, kidney, urinary bladder channel.Supplementing the kidney to control the nocturnal reducing urination, nourishing the liver to improve visual acuity.For emission and spermatorrhea, enuresis frequent micturition, impotence and premature ejaculation, order is secretly dim-sighted.
Rhizoma Cyperi: pungent, micro-hardship, micro-sweet, flat.Return liver, spleen, tri-jiao channel.Dispersing the stagnated live-QI to relieve the stagnation of QI, regulating the flow of QI to ease the stomach, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, distending pain in the chest and hypochondrium, hernia pain, distending pain of the breast, stagnation of QI in spleen and stomach, gastral cavity abdomen painful abdominal mass is vexed, distension pain, menoxenia, amenorrhea dysmenorrhea.
Lignum Sappan: sweet in the mouth, salty, pungent, cool in nature.GUIXIN, liver, stomach, spleen channel.Blood circulation promoting and blood stasis dispelling, subduing swelling and relieving pain.Married woman's amenorrhea due to stagnation of blood, dysmenorrhea, postpartum stagnation cardiac and abdominal pain, puerperal blood faints, carbuncle, traumatic injury, tetanus.
The present invention is used
Beneficial effect of the present invention: all raw material of Chinese medicine medicines of Chinese medicine composition of the present invention all can be buied from Chinese medicine shop, dialectical composition of prescription is carried out according to theory of Chinese medical science, reach effect of promoting the circulation of QI to induce diuresis, nourishing yin and warming yang, strengthening spleen and nourishing blood and heat-clearing and toxic substances removing, there is the advantage that medicine source is wide, cost is low, evident in efficacy, side effect is little, just have obvious therapeutical effect to acute glomerulonephritis.
Detailed description of the invention
embodiment 1
The Chinese medicine composition for the treatment of acute glomerulonephritis is made up of the raw material of following weight portion: an Euphorbia thymifolia 6g, Sword Jackbean Seed 1g, Herba Salsolae Collinae 15g, Herba Leontopodii Leontopodioidis 5g, Tuberous Sword Fern 3g, Fructus Cnidii 6g, Endothelium Corneum Gigeriae Galli 2g, Plumula Nelumbinis 3g, Radix Cynanchi Atrati 5g, Rhizoma Curculiginis 9g, Rhizoma Panacis Japonici 15g, Herb Gynostemmae Pentaphylli 2g, Flos et Folium Lactucae elatae 6g, Herba Cistanches 5g, Rhizoma Cimicifugae 10g, Folium Vaccinii Bracteati 6g, Dryopteris bissetiaha (Bak) C. Chr-Nephrodium bisseianum Bak 10g, Fructus Rubi 8g, Rhizoma Cyperi 10g, Lignum Sappan 9g.
embodiment 2
Preferably, a kind of Chinese medicine composition for the treatment of acute glomerulonephritis is made up of the raw material of following weight portion: Euphorbia thymifolia 8g, Sword Jackbean Seed 3g, Herba Salsolae Collinae 12g, Herba Leontopodii Leontopodioidis 6g, Tuberous Sword Fern 2g, Fructus Cnidii 7g, Endothelium Corneum Gigeriae Galli 3g, Plumula Nelumbinis 4g, Radix Cynanchi Atrati 6g, Rhizoma Curculiginis 8g, Rhizoma Panacis Japonici 10g, Herb Gynostemmae Pentaphylli 4g, Flos et Folium Lactucae elatae 7g, Herba Cistanches 4g, Rhizoma Cimicifugae 11g, Folium Vaccinii Bracteati 7g, Dryopteris bissetiaha (Bak) C. Chr-Nephrodium bisseianum Bak 8g, Fructus Rubi 7g, Rhizoma Cyperi 13g, Lignum Sappan 7g.
embodiment 3
The Chinese medicine composition for the treatment of acute glomerulonephritis is made up of the raw material of following weight portion: an Euphorbia thymifolia 10g, Sword Jackbean Seed 5g, Herba Salsolae Collinae 10g, Herba Leontopodii Leontopodioidis 7g, Tuberous Sword Fern 1g, Fructus Cnidii 8g, Endothelium Corneum Gigeriae Galli 4g, Plumula Nelumbinis 5g, Radix Cynanchi Atrati 8g, Rhizoma Curculiginis 6g, Rhizoma Panacis Japonici 5g, Herb Gynostemmae Pentaphylli 5g, Flos et Folium Lactucae elatae 8g, Herba Cistanches 3g, Rhizoma Cimicifugae 12g, Folium Vaccinii Bracteati 9g, Dryopteris bissetiaha (Bak) C. Chr-Nephrodium bisseianum Bak 5g, Fructus Rubi 6g, Rhizoma Cyperi 15g, Lignum Sappan 9g.
Below in conjunction with clinical observation, the present invention will be further described.
clinical observation
(1) clinical data
Stochastic choice make a definite diagnosis acute glomerulonephritis patient 120 example, the age 5-55 year, 27.8 years old mean age, without other serious disease.
(2) Therapeutic Method
Every side is potion, potion on the one, one day twice, point morning and evening twice one after each meal.Chinese medicine composition of the present invention decocting method routinely produces medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and covers powder, soaks 20 minutes, then adds water and do not have powder about 5 centimetres, and intense fire decocts to boiling, and turns slow fire boiling 30 minutes; Second decocts, and adds water and does not have powder about 4 centimetres, decocts 20 minutes after water boils; Decoct extracting juice twice, merge.Within 30 days, be 1 course for the treatment of, the lighter 1-2 can fully recover a course for the treatment of, and severe one 3-4 the course for the treatment of can fully recover.
(3) curative effect determinate standard
" healing ": laboratory examination, acute glomerulonephritis symptom disappears completely, recovers normal;
" effective ": laboratory examination, the basic or major part of acute glomerulonephritis symptom disappears;
" effectively ": laboratory examination, acute glomerulonephritis symptom is clearly better;
Engineering noise: laboratory examination, acute glomerulonephritis symptom is without improvement.
(4) therapeutic effect:
Clinical cure 88 example, accounts for 73.3%; Effective 18 examples, account for 15%; Effective 10 examples, account for 8.3%; Invalid 4 examples, total effective rate 96.6%.
(5) model case
Case 1: Lee, man, 20 years old.Oliguria color is red, anasarca, and tongue fur turns to be yellow, and takes Chinese medicine composition of the present invention after 15 days, and obviously improving appears in above-mentioned symptom, and continue to take 45 days, all transference cures, livelihood restoration is normal.
Case 2: pay certain, female, 38 years old.Heating, has a headache dizzy, and urine is as strong tea, and tongue fur BOHUANG, take Chinese medicine composition of the present invention after 30 days, symptom is obviously improved, and continues to take medicine of the present invention 45 days, all transference cures, and recovery from illness, livelihood restoration is normal.
Case 3: journey, man, 8 years old.Short urination is red puckery, thirsty vexed, the slight edema of limbs, pale tongue with white fur, and take Chinese medicine composition of the present invention after 20 days, symptom is obviously improved, and continues to take medicine of the present invention 20 days, transference cure, and recovery from illness, livelihood restoration is normal.
Claims (2)
1. treat a Chinese medicine composition for acute glomerulonephritis, it is characterized in that, be made up of the raw material of following weight portion: Euphorbia thymifolia 6-10 part, Sword Jackbean Seed 1-5 part, Herba Salsolae Collinae 10-15 part, Herba Leontopodii Leontopodioidis 5-7 part, Tuberous Sword Fern 1-3 part, Fructus Cnidii 6-8 part, Endothelium Corneum Gigeriae Galli 2-4 part, Plumula Nelumbinis 3-5 part, Radix Cynanchi Atrati 5-8 part, Rhizoma Curculiginis 6-9 part, Rhizoma Panacis Japonici 5-15 part, Herb Gynostemmae Pentaphylli 2-5 part, Flos et Folium Lactucae elatae 6-8 part, Herba Cistanches 3-5 part, Rhizoma Cimicifugae 10-12 part, Folium Vaccinii Bracteati 6-9 part, Dryopteris bissetiaha (Bak) C. Chr-Nephrodium bisseianum Bak 5-10 part, Fructus Rubi 6-8 part, Rhizoma Cyperi 10-15 part, Lignum Sappan 5-9 part.
2. Chinese medicine composition according to claim 1, is characterized in that, is made up of the raw material of following weight portion: Euphorbia thymifolia 8 parts, Sword Jackbean Seed 3 parts, Herba Salsolae Collinae 12 parts, Herba Leontopodii Leontopodioidis 6 parts, Tuberous Sword Fern 2 parts, Fructus Cnidii 7 parts, Endothelium Corneum Gigeriae Galli 3 parts, Plumula Nelumbinis 4 parts, Radix Cynanchi Atrati 6 parts, Rhizoma Curculiginis 8 parts, Rhizoma Panacis Japonici 10 parts, Herb Gynostemmae Pentaphylli 4 parts, Flos et Folium Lactucae elatae 7 parts, Herba Cistanches 4 parts, Rhizoma Cimicifugae 11 parts, Folium Vaccinii Bracteati 7 parts, Dryopteris bissetiaha (Bak) C. Chr-Nephrodium bisseianum Bak 8 parts, Fructus Rubi 7 parts, Rhizoma Cyperi 13 parts, Lignum Sappan 7 parts.
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