CN104548054A - Traditional Chinese medicine composition for treating gynecological diseases and preparation methods of traditional Chinese medicine composition - Google Patents

Abstract

The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating gynecological diseases. The traditional Chinese medicine composition is prepared from the following components: ginseng, radix angelicae dahuricae, rhizoma sparganic, panax notoginseng, (huai) radix rehmaniae preparate, ligusticum wallichii, ventilago leiocarpa benth, raspberry, arcangelisia loureiri, rubia cordifolia, hairyvein agrimony, perforate fleeceflower, fructus akebiae, curculigo orchioides, frankincense, herba leonuri, cistanche salsa, achyranthes bidentata, areca-nut, trogopterus dung, pangolin scales, rhizoma cyperi, red peony root, fructus cnidii, caster beans, rhizoma alismatis, cassia twig, gastrodia elata, ginger, paeonia suffruticosa, mirabilitum praeparatum, caulis spatholobi and gentiana rhodantha. A pure traditional Chinese medicine preparation is adopted, so that the traditional Chinese medicine composition is safe, free of pollution, free of toxic or side effect, reasonable in formula, significant in curative effect, and free of adverse reaction or toxic or side effect. The traditional Chinese medicine composition has the efficacies of nourishing the liver, tonifying the spleen, tonifying the kidneys, promoting the circulation of qi, dissolving phlegm, promoting blood circulation to remove blood stasis, removing hard mass and breaking stasis, has a good treatment effect on gynecological diseases, such as vaginitis, cervicitis, cervical erosion, pelvic inflammation, annexitis, hysteromyoma and ovarian cyst, and is relatively short in recovery cycle.

Description

A kind of Chinese medicine composition for the treatment of gynaecopathia and preparation method thereof

Technical field

The invention belongs to technical field of traditional Chinese pharmacology, be specifically related to a kind of Chinese medicine composition for the treatment of gynaecopathia and preparation method thereof.

Background technology

So-called gynecological is exactly that the disease suffered from of female reproductive system is just gynaecopathia.The kind of gynaecopathia can be divided a variety of, common are: hysteromyoma, ovarian cyst, vaginitis, cervicitis, cervical erosion, pelvic inflammatory disease, adnexitis, dysfunctional uterine hemorrhage, mastopathy, infertility, menoxenia etc.

Gynecological is that this is the general knowledge that people generally have because the infection of antibacterial or virus and the various physics such as malnutrition, wound or chemical factor can cause disease.Psychological factor can cause gynaecopathia, but easily ignore by people.At department of obstetrics and gynecology, usually see because psychology is unhealthy and cause or increase the weight of the case of some disease.As: dysmenorrhea is a kind of lower abdominal distention pain caused by muscular tone or spasm, sometimes with the soreness of waist, some people due to psychology immature, personality is irritated, and self-hating is a women, menstruation is regarded as the thing of " haveing bad luck " or " misery "; Also some people may have psychic trauma, or couple's sexual life is discord, and produced phobic anxiety etc., thus occurred dysmenorrhea symptom.Also some women that is never conceived for many years but the raw child of serious hope again that marries.There is amenorrhea once in a while, have again and feel sick or appetite abnormality, think conceived.After can being through inspection, there is no gestation, produce " pseudo-fetus " phenomenon.Besides menopause.This former women of being starts to enter a senile turning point, some women may the reaction of physiological function imbalance relatively more remarkable, produce the symptoms such as face flushing, perspiration, headache, giddy, insensitive, tired, insomnia.

China is populous, and economic base is weak, and public health, environmental health, Personal hygiene situation gap compared with World Developed Countries are larger.Therefore infectious disease is a kind of frequently-occurring disease in China, this kind of due to public health, environmental health, Personal hygiene and representative with gynaecopathia most in the infectious disease caused.

In numerous gynaecopathia with vulva pruritus, vaginitis comprise trichomonal vaginitis, colpitis mycotica, monilial vaginitis, amebic vaginitis, senile vaginitis and pelvic inflammatory disease, cervicitis and adnexitis etc. at most, the most general, can say that gynaecopathia is a kind of frequently-occurring disease and the commonly encountered diseases of China always, statistics shows that the sickness rate of gynaecopathia in rural area is up to more than 80%, also has 64% in small and medium-sized cities.Drastically influence work and the life of women compatriot; Simultaneously due to the puzzlement of feudal thought, after numerous women compatriot is ill, be too shy to speak out, less than hospital for treatment, so that delay therapic opportunity, develop into more serious more fearful disease as peritonitis even tumor etc., cause lifelong regret.Moreover gynaecopathia is many can affect love life and even cause man and wife to infect, because of and directly affect family harmony and happiness.

The medicine of current treatment gynaecopathia, based on Chinese medicine, as CN1140079 discloses a kind of prescription be made up of 22 taste crude drug such as Olibanum, Flos Carthami, Borneolum Syntheticums, is used for the treatment of cervical cancer, gynecological inflammation.But DeGrain, and when treating always again and again, cannot effect a radical cure all the time, make patient suffer larger misery and economic loss.

Summary of the invention

In order to overcome deficiency of the prior art, the invention provides a kind of Chinese medicine composition for the treatment of gynaecopathia.

In order to solve the problems of the technologies described above, the technical solution used in the present invention is as follows: a kind of Chinese medicine composition for the treatment of gynaecopathia, is made up of each component of following parts by weight: Radix Ginseng 1-5 weight portion, Radix Angelicae Dahuricae 1-5 weight portion, Rhizoma Sparganii 1-10 weight portion, Radix Notoginseng 1-20 weight portion, bosom Radix Rehmanniae Preparata 1-10 weight portion, Rhizoma Chuanxiong 1-20 weight portion, Radix seu Caulis Verntilaginis Leiocarpae 1-20 weight portion, Fructus Rubi 1-20 weight portion, Caulis Arcangelisiae 1-30 weight portion, Radix Rubiae 10-40 weight portion, Herba Agrimoniae 1-15 weight portion, shoulder to pull and return 5-20 weight portion, Fructus Akebiae 5-20 weight portion, Rhizoma Curculiginis 1-15 weight portion, Olibanum 1-10 weight portion, Herba Leonuri 10-30 weight portion, Herba Cistanches 1-10 weight portion, Radix Achyranthis Bidentatae 1-15 weight portion, Semen Arecae 1-10 weight portion, Oletum Trogopterori 1-15 weight portion, Squama Manis 1-10 weight portion, Rhizoma Cyperi 1-15 weight portion, Radix Paeoniae Rubra 1-13 weight portion, Fructus Cnidii 1-8 weight portion, Semen Ricini 1-6 weight portion, Rhizoma Alismatis 1-10 weight portion, Ramulus Cinnamomi 1-9 weight portion, Rhizoma Gastrodiae 1-8 weight portion, Rhizoma Zingiberis Recens 1-15 weight portion, Cortex Moutan 1-10 weight portion, watermelon crystal 1-8 weight portion, Caulis Spatholobi 1-10 weight portion, red Radix Gentianae 1-10 weight portion.

Further, the present invention also can be made up of each component of following parts by weight: Radix Ginseng 1-5 weight portion, Radix Angelicae Dahuricae 1-5 weight portion, Rhizoma Sparganii 1-10 weight portion, Radix Notoginseng 1-15 weight portion, bosom Radix Rehmanniae Preparata 1-10 weight portion, Rhizoma Chuanxiong 1-20 weight portion, Radix seu Caulis Verntilaginis Leiocarpae 1-20 weight portion, Fructus Rubi 1-20 weight portion, Caulis Arcangelisiae 1-20 weight portion, Radix Rubiae 10-30 weight portion, Herba Agrimoniae 1-10 weight portion, shoulder to pull and return 5-15 weight portion, Fructus Akebiae 5-20 weight portion, Rhizoma Curculiginis 1-15 weight portion, Olibanum 1-10 weight portion, Herba Leonuri 10-30 weight portion, Herba Cistanches 1-10 weight portion, Radix Achyranthis Bidentatae 1-15 weight portion, Semen Arecae 1-10 weight portion, Oletum Trogopterori 1-10 weight portion, Squama Manis 1-10 weight portion, Rhizoma Cyperi 1-10 weight portion, Radix Paeoniae Rubra 1-13 weight portion, Fructus Cnidii 1-8 weight portion, Semen Ricini 1-6 weight portion, Rhizoma Alismatis 1-8 weight portion, Ramulus Cinnamomi 1-5 weight portion, Rhizoma Gastrodiae 1-8 weight portion, Rhizoma Zingiberis Recens 1-10 weight portion, Cortex Moutan 1-8 weight portion, watermelon crystal 1-5 weight portion, Caulis Spatholobi 1-10 weight portion, red Radix Gentianae 1-8 weight portion.

Further, the present invention also can be made up of each component of following parts by weight: Radix Ginseng 1-5 weight portion, Radix Angelicae Dahuricae 1-5 weight portion, Rhizoma Sparganii 1-10 weight portion, Radix Notoginseng 1-15 weight portion, bosom Radix Rehmanniae Preparata 1-10 weight portion, Rhizoma Chuanxiong 1-10 weight portion, Radix seu Caulis Verntilaginis Leiocarpae 1-10 weight portion, Fructus Rubi 1-10 weight portion, Caulis Arcangelisiae 1-10 weight portion, Radix Rubiae 10-15 weight portion, Herba Agrimoniae 1-10 weight portion, shoulder to pull and return 5-15 weight portion, Fructus Akebiae 5-10 weight portion, Rhizoma Curculiginis 1-15 weight portion, Olibanum 1-10 weight portion, Herba Leonuri 10-15 weight portion, Herba Cistanches 1-10 weight portion, Radix Achyranthis Bidentatae 1-10 weight portion, Semen Arecae 1-10 weight portion, Oletum Trogopterori 1-10 weight portion, Squama Manis 1-10 weight portion, Rhizoma Cyperi 1-10 weight portion, Radix Paeoniae Rubra 1-13 weight portion, Fructus Cnidii 1-5 weight portion, Semen Ricini 1-6 weight portion, Rhizoma Alismatis 1-5 weight portion, Ramulus Cinnamomi 1-5 weight portion, Rhizoma Gastrodiae 1-5 weight portion, Rhizoma Zingiberis Recens 1-5 weight portion, Cortex Moutan 1-5 weight portion, watermelon crystal 1-5 weight portion, Caulis Spatholobi 1-10 weight portion, red Radix Gentianae 1-8 weight portion.

Further, compositions of the present invention makes vagina administration preparation with suitable adjuvant, and wherein said vagina administration preparation is selected from suppository, ointment, vagina effervescence or soft capsule.

Further, suppository of the present invention by weight part ratio be 1: 1.5-5.0 Chinese medicine composition and substrate make.

Further, substrate of the present invention is selected from one or more in semi-synthetic fatty acid glyceride, Macrogol 4000, PEG400, Tween-80, polyoxyethylene, poloxamer, glycerin gelatine, glyceryl monostearate.

Further, substrate of the present invention is the mixture of Macrogol 4000 and glycerin gelatine.

Further, present invention also offers a kind of preparation method for the treatment of the Chinese medicine composition of gynaecopathia, 1) described crude drug is pulverized and sieved powdered or through extracting obtained concentrated solution; 2) in first step gained, add adjuvant, make vagina administration preparation.

Further, the method comprises the steps:

A) Radix Notoginseng, watermelon crystal, Rhizoma Zingiberis Recens powder are broken into fine powder and cross 80-100 mesh sieve;

B) by Radix Ginseng, the Radix Angelicae Dahuricae, Rhizoma Sparganii, bosom Radix Rehmanniae Preparata, Rhizoma Chuanxiong, Radix seu Caulis Verntilaginis Leiocarpae, Fructus Rubi, Caulis Arcangelisiae, Radix Rubiae, Herba Agrimoniae, shoulder pull return, Fructus Akebiae, Rhizoma Curculiginis, Olibanum, Herba Leonuri, Herba Cistanches, Radix Achyranthis Bidentatae, Semen Arecae, Oletum Trogopterori, Squama Manis, Rhizoma Cyperi, Radix Paeoniae Rubra, Fructus Cnidii, Semen Ricini, Rhizoma Alismatis, Ramulus Cinnamomi, Rhizoma Gastrodiae, Cortex Moutan, Caulis Spatholobi, red Radix Gentianae soak by water twice, each 0.5-5h, merge decoction liquor, filter, heating is concentrated, obtains concentrated solution;

C) fine powder of a step is mixed homogeneously with the concentrated solution of b step, obtain mixed liquor;

D) in the mixed liquor of step c, add suitable adjuvant, make vagina administration preparation.

Further, the present invention also comprises the application of described compositions in treatment vaginitis, cervicitis, cervical erosion, pelvic inflammatory disease, adnexitis.

The pharmacological action of drug component of the present invention is specific as follows:

Radix Ginseng

Nature and flavor: sweet, micro-hardship are flat.

Gui Jing: return spleen, lung, heart channel.

Function cures mainly: strongly invigorating primordial QI, and multiple arteries and veins takes off admittedly, and invigorating the spleen to benefit the lung, promotes the production of body fluid, and calms the nerves.For weak body and prostration, cold extremities faint pulse, insufficiency of the spleen lack of appetite, the deficiency of the lung is breathed with cough, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, and prolonged illness void is won, palpitation with fear insomnia, sexual impotence cold womb; Heart failure, cardiogenic shock.

The Radix Angelicae Dahuricae

Nature and flavor: pungent, temperature.

Gui Jing: return stomach, large intestine, lung meridian.

Function cures mainly: loose wind dehumidifying, understand things pain-stopping, detumescence and apocenosis.For headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.

Rhizoma Sparganii

Nature and flavor: pungent, bitter are flat.

Gui Jing: return liver, spleen channel.

Function cures mainly: removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving.For lump in the abdomen mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain.

Radix Notoginseng

Nature and flavor: sweet, micro-hardship, temperature.

Gui Jing: return liver, stomach warp.

Function cures mainly: dissipating blood stasis stops blooding, subduing swelling and relieving pain.For spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling.

Bosom Radix Rehmanniae Preparata

Nature and flavor: sweet, tepor.

Gui Jing: return liver, kidney channel.

Function cures mainly: nourishing YIN and supplementing blood, and beneficial essence fills out marrow.For the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat is passed out semen, and interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, and metrostaxis is dizzy, tinnitus, early whitening of beard and hair.

Rhizoma Chuanxiong

Nature and flavor: pungent, temperature.

Gui Jing: return liver, gallbladder, pericardium channel.

Function cures mainly: blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.

Radix seu Caulis Verntilaginis Leiocarpae

Nature and flavor: sweet; Temperature

Gui Jing: lung; Spleen channel

Function cures mainly: fill blood; Bone and muscle strengthening; Relax meridians.Main deficient qi and blood; Have through uncomfortable; Blood deficiency amenorrhea; Rheumatalgia; Traumatic injury; Lumbar muscle strain.

Fructus Rubi

Nature and flavor: sweet acid; Flat; Nontoxic

Gui Jing: liver; Kidney channel

Function cures mainly: the liver and the kidney tonifying, controlling nocturnal emission with astringent drugs reducing urination, improving eyesight.Main impotence and premature ejaculation, emission and spermatorrhea, cold womb is infertile, and leukorrhagia is rare clearly, frequent micturition incontinence of urine, and blurred vision is dark, early whitening of beard and hair.

Caulis Arcangelisiae

Nature and flavor: bitter; Cold; Mild toxicity

Gui Jing: the heart; Lung; Large intestine channel

Function cures mainly: clearing away heat-damp and promoting diuresis; Eliminating fire and detoxication.Main intestinal is scorching; Bacillary dysentery; Jaundice; Malaria; Furuncle and phyma; Eczema; Vaginitis; Bronchitis; Pertussis; Tonsillitis; Eye conjunctivitis.

Radix Rubiae

Nature and flavor: bitter, cold.

Gui Jing: return Liver Channel.

Function cures mainly: removing heat from blood, and hemostasis, blood stasis dispelling, stimulates the menstrual flow.For spitting blood, epistaxis, metrorrhagia, traumatic hemorrhage, amenorrhea stasis blocking, arthralgia, tumbling and swelling.

Herba Agrimoniae

Nature and flavor: bitter, puckery are flat.

Gui Jing: GUIXIN, Liver Channel.

Function cures mainly: astringing to arrest bleeding, preventing the attack (or recurrence) of malaria, dysentery relieving, removing toxic substances.For hemoptysis, spit blood, metrostaxis, malaria, dysentery, de-power impairment caused by overstrain, carbuncle sore tumefacting virus, pudendal pruritus leukorrhagia.

Herba Polygoni Perfoliati

Nature and flavor: acid; Bitter; Property is put down

Gui Jing: lung; Small intestine meridian

Function cures mainly: heat-clearing and toxic substances removing; Inducing diuresis and reducing edema; Dissipating blood stasis stops blooding.Main furuncle carbuncle; Erysipelas; The paralysis cheek; Mastitis; Ting ear; Throat moth; Cold, fever; Cough due to lung-heat; Pertussis; Scrofula; Haemorrhoids; Lymphogranuloma inguinale inguinal bubo; Dysentery; Jaundice; Tympanites; Edema; Stranguria with turbid discharge; Leukorrhagia; Malaria; Wind-fire acute conjunctivitis; Treating swelling and pain by traumatic injury; Spit blood; Have blood in stool; Snake bite and insect sting.

Fructus Akebiae

Nature and flavor: mildly bitter flavor, property is put down.Return liver, stomach, urinary bladder channel.

Gui Jing: liver; Stomach warp

Function cures mainly: dispersing the stagnated liver-QI for regulating the stomach, promoting blood circulation and stopping pain, hard masses softening and resolving, diuresis.Main stagnation of liver-QI and stomach-QI, gastral cavity abdomen, the side of body help distending pain, and diet does not disappear, and dysentery is just let out, hernia pain, lumbago, amenorrhea dysmenorrhea, goiter scrofula, malignant tumor.

Rhizoma Curculiginis

Nature and flavor: pungent, heat; Poisonous.

Gui Jing: return kidney,liver,spleen warp.

Function cures mainly: kidney-replenishing, bone and muscle strengthening, dispelling cold and dampness.For sexual impotence cold sperm, muscles and bones flaccidity is soft, the cold numbness of waist knee joint, yang deficiency cold diarrhea.

Olibanum

Nature and flavor: acrid in the mouth; Bitter; Tepor

Gui Jing: the heart; Liver; Spleen channel

Function cures mainly: blood-activating and qi-promoting; Inducing menstruation to relieve menalgia; Detumescence and promoting granulation.Main trusted subordinate's pain; Rheumatic arthralgia; Amenorrhea dysmenorrhea; Traumatic injury stasis of blood pain; Swollen ulcer drug; Intestinal carbuncle; The sore being festered and unhealed.

Herba Leonuri

Nature and flavor: bitter, pungent, are slightly cold.

Gui Jing: return liver, pericardium channel.

Function cures mainly: promoting blood flow to regulate menstruation, inducing diuresis to remove edema.For menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema oliguria; Acute nephritis edema.

Herba Cistanches

Nature and flavor: sweet, salty, temperature.

Gui Jing: return kidney, large intestine channel.

Function cures mainly: kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation.For sexual impotence, infertile, soreness of the waist and knees, muscles and bones is unable, dryness of the intestine constipation.

Radix Achyranthis Bidentatae

Nature and flavor: bitter, sour are flat.

Gui Jing: return liver, kidney channel.

Function cures mainly: invigorating the liver and kidney, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, conducting blood to flow downwards.For soreness of waist and knee joint, muscles and bones is unable, amenorrhea lump in the abdomen, dizziness due to hyperactivity of liver-YANG.

Semen Arecae

Nature and flavor: bitter, pungent, temperature.

Gui Jing: return stomach, large intestine channel.

Function cures mainly: killing insect and eliminating accumulation, sending down the abnormal ascending QI, row water, preventing the attack (or recurrence) of malaria.For cestode, ascarid, fasciolopsiasis buski, abdominal pain due to worm stagnation, stagnant dysentery, tenesmus, edema beriberi, malaria.

Oletum Trogopterori

Nature and flavor: bitter in the mouth; Sweet; Warm in nature

Gui Jing: liver; Spleen channel

Function cures mainly: promoting blood circulation and stopping pain; Removing stasis to stop bleeding; Removing food stagnancy detoxifies.The all pains of main trusted subordinate's vim and vigour; Women's amenorrhea; The stagnant stomachache of the stasis of blood in puerperal; Metrostaxis; Infantile malnutrition; Snakes and scorpions centipete bite.

Squama Manis

Nature and flavor: salty are cool.

Gui Jing: enter Liver Channel, stomach warp.

Function cures mainly: the routed carbuncle of detumescence, searches wind active, stimulating milk secretion of stimulating the menstrual flow.Control carbuncle skin ulcer kind, anemofrigid-damp arthralgia, amenorrhea, galactostasis.External is stopped blooding.

Rhizoma Cyperi

Nature and flavor: pungent, micro-hardship, micro-sweet are flat.

Gui Jing: return liver, spleen, tri-jiao channel.

Function cures mainly: promoting QI circulation for relieving depression, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.

Radix Paeoniae Rubra

Nature and flavor: bitter, are slightly cold.

Gui Jing: return Liver Channel.

Function cures mainly: clearing away heat and cooling blood, eliminating stasis to stop pain.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, injury from falling down, carbuncle skin infection.

Fructus Cnidii

Nature and flavor: pungent, bitter, temperature; Slightly poisonous.

Gui Jing: return kidney channel.

Function cures mainly: warming the kidney to invigorate YANG, and dampness is dispeled the wind, parasite killing.For sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago; External treatment vulval eczema, married woman's pudendal pruritus; Trichomonal vaginitis.

Semen Ricini

Nature and flavor: sweet, pungent are flat; Poisonous.

Gui Jing: return large intestine, lung meridian.

Function cures mainly: poison is dialled in detumescence, rushes down lower logical stagnant.For swollen ulcer drug, sore throat, scrofula, constipation due to dry stool.

Rhizoma Alismatis

Nature and flavor: sweet, cold.

Gui Jing: return kidney, urinary bladder channel.

Function cures mainly: diuresis, clearing away damp-heat.For dysuria, edema distension, oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; Hyperlipidemia.

Ramulus Cinnamomi

Nature and flavor: acrid, sweet, warm.

Gui Jing: GUIXIN, lung, urinary bladder channel.

Function cures mainly: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.

Rhizoma Gastrodiae

Nature and flavor: sweet are flat.

Gui Jing: return Liver Channel.

Function cures mainly: suppressing the hyperactive liver to relieve the wind syndrome relieving convulsion.Dizzy for having a headache, numb limbs and tense tendons, infantile convulsion, epilepsy clonus, tetanus.

Rhizoma Zingiberis Recens

Nature and flavor: pungent, tepor.

Gui Jing: return lung, spleen, stomach warp.

Function cures mainly: induce sweat cold expelling, warming middle-JIAO to arrest vomiting, preventing phlegm from forming and stopping coughing.For anemofrigid cold, gastrofrigid vomiting, cold-phlegm is coughed.

Cortex Moutan

Nature and flavor: bitter, pungent, are slightly cold.

Gui Jing: GUIXIN, liver, kidney channel.

Function cures mainly: clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.For maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury.

Watermelon crystal

Nature and flavor: salty in the mouth; Cold in nature

Gui Jing: return spleen; Lung meridian

Function cures mainly: heat-clearing and toxic substances removing; Relieving sore throat and diminishing swelling.Main acute throat trouble; Sore throat; Mouth larynx; Aphtha; Ulcerative gingivitis; To cough outward pharynx production capacity; Conjunctival congestion and swelling pain.

Caulis Spatholobi

Nature and flavor: bitter, sweet, temperature.

Gui Jing: return liver, kidney channel.

Function cures mainly: enrich blood, and invigorates blood circulation, dredging collateral.For menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.

Red Radix Gentianae

Nature and flavor: bitter, cold.

Function cures mainly: clearing away heat-damp and promoting diuresis, removing toxic substances.For acute icterohepatitis, dysentery, infantile pneumonia, bronchitis, bronchial asthma, pulmonary tuberculosis, tuberculous lymphadenitis, dysuria, eye conjunctivitis; Carbuncle furuncle infections is controlled in external, burn and scald.

In sum, the present invention has liver nourishing, spleen invigorating, the kidney invigorating, there is circulation of qi promoting expectorant, blood circulation promoting and blood stasis dispelling, effects such as knot of assaulting fortified position brokenly, to gynaecopathia vaginitis, cervicitis, cervical erosion, pelvic inflammatory disease, adnexitis, hysteromyoma and ovarian cyst, there is good therapeutic effect, and the cycle of healing is shorter.In addition, the present invention can be widely used in the pathogenic former caused gynecological inflammation such as antibacterial, fungus, protozoon, chlamydia, mycoplasma, and meanwhile, this Chinese medicine preparation also has the growth and breeding suppressing pathogenic microorganism or protozoon.Therefore, in treatment gynecological inflammation, determined curative effect, has no side effect, not wound body, and fundamentally can nurse one's health the health of patient, does not recur, do not stay sequela after patient is recovered.

Detailed description of the invention

Below in conjunction with specific embodiment, the present invention is further elaborated.

Embodiment 1

The raw material composition of effective ingredient of the present invention and parts by weight are: a kind of Chinese medicine composition for the treatment of gynaecopathia, be made up of each component of following parts by weight: Radix Ginseng 1 weight portion, the Radix Angelicae Dahuricae 1 weight portion, Rhizoma Sparganii 8 weight portion, Radix Notoginseng 10 weight portion, bosom Radix Rehmanniae Preparata 2 weight portion, Rhizoma Chuanxiong 3 weight portion, Radix seu Caulis Verntilaginis Leiocarpae 10 weight portion, Fructus Rubi 8 weight portion, Caulis Arcangelisiae 3 weight portion, Radix Rubiae 10 weight portion, Herba Agrimoniae 4 weight portion, shoulder to pull and return 6 weight portions, Fructus Akebiae 5 weight portion, Rhizoma Curculiginis 2 weight portion, Olibanum 3 weight portion, Herba Leonuri 10 weight portion, Herba Cistanches 8 weight portion, Radix Achyranthis Bidentatae 3 weight portion, Semen Arecae 4 weight portion, Oletum Trogopterori 3 weight portion, Squama Manis 4 weight portion, Rhizoma Cyperi 3 weight portion, Radix Paeoniae Rubra 2 weight portion, Fructus Cnidii 2 weight portion, Semen Ricini 3 amount part, Rhizoma Alismatis 2 weight portion, Ramulus Cinnamomi 4 weight portion, Rhizoma Gastrodiae 1 weight portion, Rhizoma Zingiberis Recens 3 weight portion, Cortex Moutan 4 weight portion, watermelon crystal 5 weight portion, Caulis Spatholobi 2 weight portion, red Radix Gentianae 3 weight portion.

Compositions of the present invention makes vagina administration preparation with suitable adjuvant, and wherein said vagina administration preparation is selected from suppository.Suppository of the present invention by weight part ratio be 1: 1.5 Chinese medicine composition and substrate make.Substrate of the present invention is the mixture of Macrogol 4000 and glycerin gelatine.

The preparation method of the Chinese medicine composition of above-mentioned treatment gynaecopathia, 1) described crude drug is pulverized and sieved powdered or through extracting obtained concentrated solution; 2) in first step gained, add adjuvant, make vagina administration preparation.

The method comprises the steps:

A) Radix Notoginseng, watermelon crystal, Rhizoma Zingiberis Recens powder are broken into fine powder and cross 80-100 mesh sieve;

B) by Radix Ginseng, the Radix Angelicae Dahuricae, Rhizoma Sparganii, bosom Radix Rehmanniae Preparata, Rhizoma Chuanxiong, Radix seu Caulis Verntilaginis Leiocarpae, Fructus Rubi, Caulis Arcangelisiae, Radix Rubiae, Herba Agrimoniae, shoulder pull return, Fructus Akebiae, Rhizoma Curculiginis, Olibanum, Herba Leonuri, Herba Cistanches, Radix Achyranthis Bidentatae, Semen Arecae, Oletum Trogopterori, Squama Manis, Rhizoma Cyperi, Radix Paeoniae Rubra, Fructus Cnidii, Semen Ricini, Rhizoma Alismatis, Ramulus Cinnamomi, Rhizoma Gastrodiae, Cortex Moutan, Caulis Spatholobi, red Radix Gentianae soak by water twice, each 0.5-5h, merge decoction liquor, filter, heating is concentrated, obtains concentrated solution;

C) fine powder of a step is mixed homogeneously with the concentrated solution of b step, obtain mixed liquor; D) in the mixed liquor of step c, add the mixture of Macrogol 4000 and glycerin gelatine, be 1: 1.5 with the ratio of mixed liquor, be mixed and made into vagina administration suppository formulations.

Described compositions can treat vaginitis, cervicitis, cervical erosion, pelvic inflammatory disease, adnexitis.

Embodiment 2

The raw material composition of effective ingredient of the present invention and parts by weight are: Radix Ginseng 1 weight portion, the Radix Angelicae Dahuricae 2 weight portion, Rhizoma Sparganii 3 weight portion, Radix Notoginseng 3 weight portion, bosom Radix Rehmanniae Preparata 5 weight portion, Rhizoma Chuanxiong 6 weight portion, Radix seu Caulis Verntilaginis Leiocarpae 4 weight portion, Fructus Rubi 3 weight portion, Caulis Arcangelisiae 4 weight portion, Radix Rubiae 10 weight portion, Herba Agrimoniae 5 weight portion, shoulder to pull and return 6 weight portions, Fructus Akebiae 10 weight portion, Rhizoma Curculiginis 10 weight portion, Olibanum 3 weight portion, Herba Leonuri 11 weight portion, Herba Cistanches 5 weight portion, Radix Achyranthis Bidentatae 5 weight portion, Semen Arecae 3 weight portion, Oletum Trogopterori 8 weight portion, Squama Manis 4 weight portion, Rhizoma Cyperi 6 weight portion, Radix Paeoniae Rubra 7 weight portion, Fructus Cnidii 3 weight portion, Semen Ricini 4 weight portion, Rhizoma Alismatis 2 weight portion, Ramulus Cinnamomi 2 weight portion, Rhizoma Gastrodiae 2 weight portion, Rhizoma Zingiberis Recens 3 weight portion, Cortex Moutan 2 weight portion, watermelon crystal 2 weight portion, Caulis Spatholobi 3 weight portion, red Radix Gentianae 4 weight portion.

Compositions of the present invention makes vagina administration preparation with suitable adjuvant, and wherein said vagina administration preparation is selected from suppository.Suppository of the present invention is 1 by weight part ratio _:chinese medicine composition and the substrate of 1.5 are made.Substrate of the present invention is the mixture of Macrogol 4000 and glycerin gelatine.

The each method of system of the Chinese medicine composition of above-mentioned treatment gynaecopathia, 1) described crude drug is pulverized and sieved powdered or through extracting obtained concentrated solution; 2) in first step gained, add adjuvant, make vagina administration preparation.

The method comprises the steps:

A) Radix Notoginseng, watermelon crystal, Rhizoma Zingiberis Recens powder are broken into fine powder and cross 80-100 mesh sieve;

B) by Radix Ginseng, the Radix Angelicae Dahuricae, Rhizoma Sparganii, bosom Radix Rehmanniae Preparata, Rhizoma Chuanxiong, Radix seu Caulis Verntilaginis Leiocarpae, Fructus Rubi, Caulis Arcangelisiae, Radix Rubiae, Herba Agrimoniae, shoulder pull return, Fructus Akebiae, Rhizoma Curculiginis, Olibanum, Herba Leonuri, Herba Cistanches, Radix Achyranthis Bidentatae, Semen Arecae, Oletum Trogopterori, Squama Manis, Rhizoma Cyperi, Radix Paeoniae Rubra, Fructus Cnidii, Semen Ricini, Rhizoma Alismatis, Ramulus Cinnamomi, Rhizoma Gastrodiae, Cortex Moutan, Caulis Spatholobi, red Radix Gentianae soak by water twice, each 0.5-5h, merge decoction liquor, filter, heating is concentrated, obtains concentrated solution;

C) fine powder of a step is mixed homogeneously with the concentrated solution of b step, obtain mixed liquor; D) in the mixed liquor of step c, add the mixture of Macrogol 4000 and glycerin gelatine, be 1: 1.5 with the ratio of mixed liquor, be mixed and made into vagina administration suppository formulations.

Described compositions can treat vaginitis, cervicitis, cervical erosion, pelvic inflammatory disease, adnexitis.

Embodiment 3

The raw material composition of effective ingredient of the present invention and parts by weight are: Radix Ginseng 2 weight portion, the Radix Angelicae Dahuricae 4 weight portion, Rhizoma Sparganii 5 amount part, Radix Notoginseng 6 weight portion, bosom Radix Rehmanniae Preparata 7 weight portion, Rhizoma Chuanxiong 5 weight portion, Radix seu Caulis Verntilaginis Leiocarpae 3 weight portion, Fructus Rubi 2 weight portion, Caulis Arcangelisiae 5 weight portion, Radix Rubiae 8 weight portion, Herba Agrimoniae 6 weight portion, shoulder to pull and return 5 weight portions, Fructus Akebiae 12 weight portion, Rhizoma Curculiginis 15 weight portion, Olibanum 2 weight portion, Herba Leonuri 10 weight portion, Herba Cistanches 4 weight portion, Radix Achyranthis Bidentatae 4 weight portion, Semen Arecae 5 weight portion, Oletum Trogopterori 5 weight portion, Squama Manis 5 weight portion, Rhizoma Cyperi 5 weight portion, Radix Paeoniae Rubra 6 weight portion, Fructus Cnidii 2 weight portion, Semen Ricini 3 weight portion, Rhizoma Alismatis 3 weight portion, Ramulus Cinnamomi 3 weight portion, Rhizoma Gastrodiae 2 weight portion, Rhizoma Zingiberis Recens 3 weight portion, Cortex Moutan 3 weight portion, watermelon crystal 2 weight portion, Caulis Spatholobi 3 weight portion, red Radix Gentianae 5 weight portion.

Compositions of the present invention makes vagina administration preparation with suitable adjuvant, and wherein said vagina administration preparation is selected from suppository.Suppository of the present invention is 1 by weight part ratio _:chinese medicine composition and the substrate of 1.5 are made.Substrate of the present invention is Macrogol 4000.

The preparation method of the Chinese medicine composition of above-mentioned treatment gynaecopathia, 1) described crude drug is pulverized and sieved powdered or through extracting obtained concentrated solution; 2) in first step gained, add adjuvant, make vagina administration preparation.

The method comprises the steps:

A) Radix Notoginseng, watermelon crystal, Rhizoma Zingiberis Recens powder are broken into fine powder and cross 80-100 mesh sieve;

B) by Radix Ginseng, the Radix Angelicae Dahuricae, Rhizoma Sparganii, bosom Radix Rehmanniae Preparata, Rhizoma Chuanxiong, Radix seu Caulis Verntilaginis Leiocarpae, Fructus Rubi, Caulis Arcangelisiae, Radix Rubiae, Herba Agrimoniae, shoulder pull return, Fructus Akebiae, Rhizoma Curculiginis, Olibanum, Herba Leonuri, Herba Cistanches, Radix Achyranthis Bidentatae, Semen Arecae, Oletum Trogopterori, Squama Manis, Rhizoma Cyperi, Radix Paeoniae Rubra, Fructus Cnidii, Semen Ricini, Rhizoma Alismatis, Ramulus Cinnamomi, Rhizoma Gastrodiae, Cortex Moutan, Caulis Spatholobi, red Radix Gentianae soak by water twice, each 0.5-5h, merge decoction liquor, filter, heating is concentrated, obtains concentrated solution;

C) fine powder of a step is mixed homogeneously with the concentrated solution of b step, obtain mixed liquor; D) in the mixed liquor of step c, add Macrogol 4000, be 1: 1.5 with the ratio of mixed liquor, be mixed and made into vagina administration suppository formulations.

Described compositions can treat vaginitis, cervicitis, cervical erosion, pelvic inflammatory disease, adnexitis.

Embodiment 4

The raw material composition of effective ingredient of the present invention and parts by weight are: Radix Ginseng 3 weight portion, the Radix Angelicae Dahuricae 3 weight portion, Rhizoma Sparganii 10 amount part, Radix Notoginseng 15 weight portion, bosom Radix Rehmanniae Preparata 8 weight portion, Rhizoma Chuanxiong 3 weight portion, Radix seu Caulis Verntilaginis Leiocarpae 2 weight portion, Fructus Rubi 6 weight portion, Caulis Arcangelisiae 6 weight portion, Radix Rubiae 15 weight portion, Herba Agrimoniae 3 weight portion, shoulder to pull and return 15 weight portions, Fructus Akebiae 10 weight portion, Rhizoma Curculiginis 9 weight portion, Olibanum 1 weight portion, Herba Leonuri 10 weight portion, Herba Cistanches 1 weight portion, Radix Achyranthis Bidentatae 1 weight portion, Semen Arecae 5 weight portion, Oletum Trogopterori 5 weight portion, Squama Manis 5 weight portion, Rhizoma Cyperi 5 weight portion, Radix Paeoniae Rubra 6 weight portion, Fructus Cnidii 2 weight portion, Semen Ricini 3 weight portion, Rhizoma Alismatis 3 weight portion, Ramulus Cinnamomi 3 weight portion, Rhizoma Gastrodiae 2 weight portion, Rhizoma Zingiberis Recens 3 weight portion, Cortex Moutan 3 weight portion, watermelon crystal 2 weight portion, Caulis Spatholobi 3 weight portion, red Radix Gentianae 5 weight portion.

Compositions of the present invention makes vagina administration preparation with suitable adjuvant, and wherein said vagina administration preparation is selected from soft capsule.Soft capsule of the present invention by weight part ratio be 1: 1.5 Chinese medicine composition and substrate make.The preparation method of the Chinese medicine composition of above-mentioned treatment gynaecopathia, 1) described crude drug is pulverized and sieved powdered or through extracting obtained concentrated solution; Vacuum drying dry mastic, pulverizes to obtain powder by dry mastic.

2) in first step gained, add capsule adjuvant, pour into soft capsule.

The method comprises the steps:

A) Radix Notoginseng, watermelon crystal, Rhizoma Zingiberis Recens powder are broken into fine powder and cross 80-100 mesh sieve;

B) by Radix Ginseng, the Radix Angelicae Dahuricae, Rhizoma Sparganii, bosom Radix Rehmanniae Preparata, Rhizoma Chuanxiong, Radix seu Caulis Verntilaginis Leiocarpae, Fructus Rubi, Caulis Arcangelisiae, Radix Rubiae, Herba Agrimoniae, shoulder pull return, Fructus Akebiae, Rhizoma Curculiginis, Olibanum, Herba Leonuri, Herba Cistanches, Radix Achyranthis Bidentatae, Semen Arecae, Oletum Trogopterori, Squama Manis, Rhizoma Cyperi, Radix Paeoniae Rubra, Fructus Cnidii, Semen Ricini, Rhizoma Alismatis, Ramulus Cinnamomi, Rhizoma Gastrodiae, Cortex Moutan, Caulis Spatholobi, red Radix Gentianae soak by water twice, each 0.5-5h, merge decoction liquor, filter, heating is concentrated, obtains concentrated solution; Vacuum drying dry mastic, pulverizes to obtain powder by dry mastic.

C) fine powder of a step is mixed homogeneously with the powder of b step, obtain mixed-powder; D) in the mixed-powder of step c, add capsule adjuvant, mixing pours into soft capsule.

Described compositions can treat vaginitis, cervicitis, cervical erosion, pelvic inflammatory disease, adnexitis.

Embodiment 5

Toxicity test:

In order to verify safety of the present invention, acute toxicity testing:

The medicine made to embodiment 1 to 4 has carried out white mice acute toxicity testing.The made medicine of embodiment 1 to 4 is to the continuous gavage 7d of mice, and having no white mice has the visible poisoning symptom of naked eyes and death, and the body weight change of white mice, liver, kidney body than all with blank group without significant difference, hematological indices is without obvious change.

Skin Irritation Test

Suppository embodiment 1 made is to district's coating of losing hair or feathers on the left of intact skin and damaged skin SD rat back, lose hair or feathers on the right side of each SD rat back the bare substrate suppository of district's coating with area, often organize 5,24h administration, continuous one week, the suppository that removing SD rat back is residual, observes erythema and the swelling situation at local application position after drug withdrawal.Result shows

This medicine that embodiment 1 is made to rat without obvious irritation.Toxicology test research shows, medicine of the present invention is to SD rat intact skin and damaged skin avirulence and zest, and in sum, ointment provided by the invention is safer, and it is without any side effects for SD rat that data show the present invention.

Clinical trial:

Therapeutic scheme: take the circumstances into consideration administration according to the state of an illness.

Use the Chinese medicine suppository that the embodiment of the present invention 1 provides, 1 time on the one, surrounding is a course for the treatment of, and use four courses for the treatment of, clinical observation, does not find obvious adverse reaction, and curative effect is in table 1.

Disease	Patient	Cure	Effective	Effectively	Effective percentage
						Ovarian cyst	102	81	10	5	94.11％
Cervicitis	93	73	11	5	95.69％

As visible in above-mentioned table 1, the present invention treats gynecological inflammation obvious effective rate more than 90%, has significant curative effect (P < 0.05) to cervicitis and ovarian cyst.

Model case:

Case 1 Liu 27 years old

Clinical symptoms: married unpregnancy, menstrual cycle is chaotic for many years, abdominal pain during menstruation.Through the black dull oily stasis of blood block of color, oneself touches on the right side of lower abdomen has a lump to be that ovum gallinaceum is large, is diagnosed as right ovary cyst: 6cm × 8cm × 4cm through examination in hospital.

Therapeutic process: the Chinese medicine suppository that provides of embodiment 1 is provided: one time 1,1 time on the one, surrounding is a course for the treatment of, rehabilitation.

Case 2 Zhang 52 years old

Symptom: endometriosis.Control with blood circulation promoting and blood stasis dispelling, dispersing cold for relieving pain.。

Therapeutic process: the Chinese medicine suppository that provides of embodiment 1 is provided: one time 1,1 time on the one three weeks is a course for the treatment of, rehabilitation.

The above; it is only most preferred embodiment of the present invention; not any pro forma restriction is done to the present invention; any those of ordinary skill in the art; do not departing under technical solution of the present invention ambit; utilize the method content of above-mentioned announcement to make many possible variations and modification to technical solution of the present invention, all belong to the scope of claims protection.

Claims (10)

1. treat a Chinese medicine composition for gynaecopathia, it is characterized in that: be made up of each component of following parts by weight: Radix Ginseng 1-5 weight portion, Radix Angelicae Dahuricae 1-5 weight portion, Rhizoma Sparganii 1-10 weight portion, Radix Notoginseng 1-20 weight portion, bosom Radix Rehmanniae Preparata 1-10 weight portion, Rhizoma Chuanxiong 1-20 weight portion, Radix seu Caulis Verntilaginis Leiocarpae 1-20 weight portion, Fructus Rubi 1-20 weight portion, Caulis Arcangelisiae 1-30 weight portion, Radix Rubiae 10-40 weight portion, Herba Agrimoniae 1-15 weight portion, shoulder to pull and return 5-20 weight portion, Fructus Akebiae 5-20 weight portion, Rhizoma Curculiginis 1-15 weight portion, Olibanum 1-10 weight portion, Herba Leonuri 10-30 weight portion, Herba Cistanches 1-10 weight portion, Radix Achyranthis Bidentatae 1-15 weight portion, Semen Arecae 1-10 weight portion, Oletum Trogopterori 1-15 weight portion, Squama Manis 1-10 weight portion, Rhizoma Cyperi 1-15 weight portion, Radix Paeoniae Rubra 1-13 weight portion, Fructus Cnidii 1-8 weight portion, Semen Ricini 1-6 weight portion, Rhizoma Alismatis 1-10 weight portion, Ramulus Cinnamomi 1-9 weight portion, Rhizoma Gastrodiae 1-8 weight portion, Rhizoma Zingiberis Recens 1-15 weight portion, Cortex Moutan 1-10 weight portion, watermelon crystal 1-8 weight portion, Caulis Spatholobi 1-10 weight portion, red Radix Gentianae 1-10 weight portion.

2. a kind of Chinese medicine composition for the treatment of gynaecopathia according to claim 1, is characterized in that: be made up of each component of following parts by weight: Radix Ginseng 1-5 weight portion, Radix Angelicae Dahuricae 1-5 weight portion, Rhizoma Sparganii 1-10 weight portion, Radix Notoginseng 1-15 weight portion, bosom Radix Rehmanniae Preparata 1-10 weight portion, Rhizoma Chuanxiong 1-20 weight portion, Radix seu Caulis Verntilaginis Leiocarpae 1-20 weight portion, Fructus Rubi 1-20 weight portion, Caulis Arcangelisiae 1-20 weight portion, Radix Rubiae 10-30 weight portion, Herba Agrimoniae 1-10 weight portion, shoulder to pull and return 5-15 weight portion, Fructus Akebiae 5-20 weight portion, Rhizoma Curculiginis 1-15 weight portion, Olibanum 1-10 weight portion, Herba Leonuri 10-30 weight portion, Herba Cistanches 1-10 weight portion, Radix Achyranthis Bidentatae 1-15 weight portion, Semen Arecae 1-10 weight portion, Oletum Trogopterori 1-10 weight portion, Squama Manis 1-10 weight portion, Rhizoma Cyperi 1-10 weight portion, Radix Paeoniae Rubra 1-13 weight portion, Fructus Cnidii 1-8 weight portion, Semen Ricini 1-6 weight portion, Rhizoma Alismatis 1-8 weight portion, Ramulus Cinnamomi 1-5 weight portion, Rhizoma Gastrodiae 1-8 weight portion, Rhizoma Zingiberis Recens 1-10 weight portion, Cortex Moutan 1-8 weight portion, watermelon crystal 1-5 weight portion, Caulis Spatholobi 1-10 weight portion, red Radix Gentianae 1-8 weight portion.

3. according to a kind of Chinese medicine composition for the treatment of gynaecopathia described in claim 1 to 2, it is characterized in that: be made up of each component of following parts by weight: Radix Ginseng 1-5 weight portion, Radix Angelicae Dahuricae 1-5 weight portion, Rhizoma Sparganii 1-10 weight portion, Radix Notoginseng 1-15 weight portion, bosom Radix Rehmanniae Preparata 1-10 weight portion, Rhizoma Chuanxiong 1-10 weight portion, Radix seu Caulis Verntilaginis Leiocarpae 1-10 weight portion, Fructus Rubi 1-10 weight portion, Caulis Arcangelisiae 1-10 weight portion, Radix Rubiae 10-15 weight portion, Herba Agrimoniae 1-10 weight portion, shoulder to pull and return 5-15 weight portion, Fructus Akebiae 5-10 weight portion, Rhizoma Curculiginis 1-15 weight portion, Olibanum 1-10 weight portion, Herba Leonuri 10-15 weight portion, Herba Cistanches 1-10 weight portion, Radix Achyranthis Bidentatae 1-10 weight portion, Semen Arecae 1-10 weight portion, Oletum Trogopterori 1-10 weight portion, Squama Manis 1-10 weight portion, Rhizoma Cyperi 1-10 weight portion, Radix Paeoniae Rubra 1-13 weight portion, Fructus Cnidii 1-5 weight portion, Semen Ricini 1-6 weight portion, Rhizoma Alismatis 1-5 weight portion, Ramulus Cinnamomi 1-5 weight portion, Rhizoma Gastrodiae 1-5 weight portion, Rhizoma Zingiberis Recens 1-5 weight portion, Cortex Moutan 1-5 weight portion, watermelon crystal 1-5 weight portion, Caulis Spatholobi 1-10 weight portion, red Radix Gentianae 1-8 weight portion.

4. a kind of Chinese medicine composition for the treatment of gynaecopathia according to claims 1 to 3, it is characterized in that: described compositions makes vagina administration preparation with suitable adjuvant, and wherein said vagina administration preparation is selected from suppository, ointment, vagina effervescence or soft capsule.

5. a kind of Chinese medicine composition for the treatment of gynaecopathia according to claim 4, is characterized in that: described suppository by weight part ratio be 1: 1.5-5.0 Chinese medicine composition and substrate make.

6. a kind of Chinese medicine composition for the treatment of gynaecopathia according to claim 5, is characterized in that: described substrate be selected from semi-synthetic fatty acid glyceride, Macrogol 4000, PEG400, Tween-80, polyoxyethylene, poloxamer, glycerin gelatine, glyceryl monostearate one or more.

7. a kind of Chinese medicine composition for the treatment of gynaecopathia according to claim 6, is characterized in that, described substrate is the mixture of Macrogol 4000 and glycerin gelatine.

8., according to a kind of preparation method for the treatment of the Chinese medicine composition of gynaecopathia described in claim 1 to 7, it is characterized in that, 1) described crude drug is pulverized and sieved powdered or through extracting obtained concentrated solution; 2) in first step gained, add adjuvant, make vagina administration preparation.

9. the preparation method of Chinese medicine composition according to claim 8, is characterized in that, the method comprises the steps:

A) Radix Notoginseng, watermelon crystal, Rhizoma Zingiberis Recens powder are broken into fine powder and cross 80-100 mesh sieve;

B) by Radix Ginseng, the Radix Angelicae Dahuricae, Rhizoma Sparganii, bosom Radix Rehmanniae Preparata, Rhizoma Chuanxiong, Radix seu Caulis Verntilaginis Leiocarpae, Fructus Rubi, Caulis Arcangelisiae, Radix Rubiae, Herba Agrimoniae, shoulder pull return, Fructus Akebiae, Rhizoma Curculiginis, Olibanum, Herba Leonuri, Herba Cistanches, Radix Achyranthis Bidentatae, Semen Arecae, Oletum Trogopterori, Squama Manis, Rhizoma Cyperi, Radix Paeoniae Rubra, Fructus Cnidii, Semen Ricini, Rhizoma Alismatis, Ramulus Cinnamomi, Rhizoma Gastrodiae, Cortex Moutan, Caulis Spatholobi, red Radix Gentianae soak by water twice, each 0.5-5h, merge decoction liquor, filter, heating is concentrated, obtains concentrated solution;

C) fine powder of a step is mixed homogeneously with the concentrated solution of b step, obtain mixed liquor;

D) in the mixed liquor of step c, add suitable adjuvant, make vagina administration preparation.

10. according to the Chinese medicine composition described in claim 1 to 9, it is characterized in that: in the application for the treatment of vaginitis, cervicitis, cervical erosion, pelvic inflammatory disease, adnexitis.