CN104435590A - Traditional Chinese medicine prescription for treating chronic pelvic inflammation and preparation method thereof - Google Patents
Traditional Chinese medicine prescription for treating chronic pelvic inflammation and preparation method thereof Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A61K36/88—Liliopsida (monocotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
Abstract
The invention discloses a traditional Chinese medicine prescription for treating chronic pelvic inflammation. The traditional Chinese medicine prescription for treating chronic pelvic inflammation is prepared from the following raw materials in parts by weight: 20-40 parts of ligusticum wallichii, 3-7 parts of green onion, 15-25 parts of radix cyathulae, 15-25 parts of Sichuan pepper, 10-20 parts of cockscomb, 6-18 parts of rhizoma cyperi, 20-30 parts of dragon bone, 25-40 parts of honeysuckle, 8-13 parts of coptis chinensis, 13-28 parts of radix bupleuri and 15-25 parts of wild chrysanthemum flower. The traditional Chinese medicine prescription for treating chronic pelvic inflammation disclosed by the invention has the characteristics of being simple to prepare, convenient to take and carry, and easy to take for a long time; the traditional Chinese medicine prescription has the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, removing accumulation and stasis, and promoting qi circulation to relieve pain.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Chinese medicinal formulae for the treatment of chronic pelvic inflammatory disease and preparation method thereof.
Background technology
Chronic pelvic inflammatory disease refers to female internal genital organs and surrounding connective tissue, pelvic peritoneal chronic inflammatory disease.Often thoroughly do not treat for acute pelvic inflammatory disease, when patient's body constitution is poor, the course of disease of acute pelvic inflammatory disease can be delayed and recurrent exerbation, causes chronic pelvic inflammatory disease; But also can without acute pelvic inflammation medical history process, salpingitis caused by chlamydia trachomatis infection.The chronic pelvic inflammatory disease state of an illness is more obstinate, can cause menoxenia, leucorrhoea grow in quantity, waist abdomen pain and infertile etc.
The cause of disease 1. immune factor is worked as nature defense function and is destroyed, or body's immunity declines, endocrine changes or exogenous pathogenic bacterium invade, and also can cause the generation of inflammation.2. state of an illness migration acute pelvic inflammatory disease is as thoroughly treated, and the course of disease is delayed and chronic pelvic inflammatory disease occurs; Also may due to adjacent organs inflammation direct extension, such as appendicitis, peritonitis etc. spread to pelvic cavity, cause the generation of chronic pelvic inflammatory disease.Pathogen is based on Escherichia coli.3. chlamydia infection patient can without acute pelvic inflammation medical history, and caused by chlamydia trachomatis infection.4. pathological change part chronic pelvic inflammatory disease is the pathological change that acute pelvic inflammatory disease is left over, and pathogen-free domestic exists.5. puerperal, post-abortion and gynecologic surgery operation and invasive inspection pelvic cavity being had to certain infringement as various in the dilatation and curettage, hydrotubation, hysterosalpingography, hysteroscopy, artificial abortion etc., or do not strictly observe aseptic principle, reproductive tract mucosa injury, hemorrhage, downright bad can be caused, cause the up infection of the pathogen of Lower genital tract endogenous flora.6. pelvic inflammatory disease relevant to sexual activity and age mostly occurs property active phase women, and the especially first sexual intercourse age is little, have multiple sex partner, sexual intercourse overfrequency and sex partner sexual transmission disease patient.7. the sexually transmitted disease (STD) of lower genital tract infection Lower genital tract, as Diplococcus gonorrhoeae cervicitis, chlamydia cervicitis and bacterial vaginosis by the connection of Lower genital tract and pelvic cavity, and then can cause the generation of pelvic inflammation.8. sex hygiene is bad uses unclean menopad, bath in a tub etc. due in Progressive symmetric erythrokeratodermia behavior in menstrual period, and pathogen all can be made to invade and cause inflammation.In addition, do not note sexual health care, be negligent of carry out vaginadouche person, the incidence rate of pelvic inflammatory disease is high.9. the extensive adhesion of pelvic cavity caused by chronic pelvic inflammatory disease (PID) acute attack PID, fallopian tube damage, fallopian tube defence capability declines, and easily causes subinfection again, and Relapse rate shows effect, and causes the acute attack of chronic pelvic inflammatory disease.
Clinical manifestation 1. symptom: the cicatricial adhesion that (1) chronic pelvic pain chronic inflammatory disease is formed and pelvic congestion, often cause hypogastric region falling inflation, pain and lumbosacral region to ache.Be everlasting fatigue, stand for a long time, after sexual intercourse and aggravate before and after menstruation.Severe one affects work.(2) infertile and ectopic pregnancy fallopian tube adhesion obstruction can cause infertile and ectopic pregnancy.After acute pelvic inflammatory disease, infertile incidence rate is 20% ~ 30%.And along with the development of the state of an illness, incidence of infertility presents ascendant trend.(3) irregular menstruation endometritis often have leucorrhoea grow in quantity, menoxenia, through the many dysmenorrheas of blood volume, dyspareunia; Pelvic congestion can cause menorrhagia; Menoxenia can be caused during ovarian function infringement.(4) how not obvious General Symptoms is, sometimes only has low grade fever, and susceptible is tired.Because the course of disease time is longer, can there is neurasthenia symptom in some patients, as lassitude, whole body discomfort, insomnia etc.When patient's resistance difference, easily there is acute or subacute outbreak.2. sign: general signs: the many hypsokinesis in uterus, limitation of activity or adhesion are fixed; Or fallopian tube increases thick tenderness; Or touch cystic enclosed mass; Or the other lamellar in uterus thickens tenderness etc.(1) if endometritis, uterus increases, tenderness; If salpingitis, then contact the thick fallopian tube of increasing in rope strip in one or both sides, uterus, and have mild tenderness.(2) if hydrosalpinx or tubo-ovarian cyst, then touch Cystic lesions in pelvic cavity one or both sides, how limited activity is.(3) if inflammation of pelvic connective tissue time, uterus is often in retroversioflexion, and limitation of activity or adhesion are fixed, and one or both sides, uterus have lamellar to thicken, tenderness, and uterosacral ligament often increases thick, hardening, has tenderness.
Authorization Notice No. CN 102940721 B(application number 201210494255.9) Chinese patent literature disclose a kind of medicine for the treatment of chronic pelvic inflammatory disease, it is characterized in that it is made up of the crude drug of following weight proportion: Caulis Sargentodoxae 30 parts, Herba Patriniae 30 parts, Radix Paeoniae Rubra 15 parts, Cortex Moutan 15 parts, Radix Salviae Miltiorrhizae 20 parts, Herba Taraxaci 30 parts, Fructus Forsythiae 20 parts, Cortex Phellodendri 10 parts, Radix Cyathulae 20 parts, Herba Houttuyniae 10 parts, Rhizoma Corydalis 10 parts, said medicine is put in mortar successively and is ground well, cross 100 mesh sieves, then divide
Fill two pouches.Authorization Notice No. CN 102920916 B(application number 201210470830.1) Chinese patent literature disclose a kind of decoction for the treatment of chronic pelvic inflammatory disease, it is characterized in that it is made up of the material of following weight proportioning: Wang Buliu
Row 8 parts, Herba Cistanches 10 parts, Radix Polygalae 5 parts, Flos Celosiae Cristatae 5 parts, Herba Sedi 5 parts, Fructus Quisqualis 5 parts, Flos Albiziae 10 parts, Spica Prunellae 5 parts, Fructus Gardeniae 10 parts, Radix Et Rhizoma Nardostachyos 15 parts, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 25 parts, Radix Notoginseng 15 parts, Sanguis Draxonis 15 parts, Pseudobulbus Cremastrae Seu Pleiones 15 parts, Fructus Ligustri Lucidi 25 parts and 100 parts, water.
In a word, Chinese medicine achieves good curative effect in treatment primary disease, but also there are some problems: desirable not enough to heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, Xiao Disorder eliminating stagnation, promoting the circulation of QI to relieve pain etc. clinically, has much room for improvement to improving the misery that chronic pelvic inflammatory disease brings.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide and a kind ofly prepare simple, taking convenience, be easy to carry, a kind of Chinese medicinal formulaes for the treatment of chronic pelvic inflammatory disease and preparation method thereof of easy clothes for a long time.This Chinese medicinal formulae has effect of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, Xiao Disorder eliminating stagnation, promoting the circulation of QI to relieve pain.
Technical scheme of the present invention is:
Treat a Chinese medicinal formulae for chronic pelvic inflammatory disease, be prepared from by the crude drug of following weight proportioning: Rhizoma Chuanxiong 20-40 part, Herba Alii fistulosi 3-7 part, Radix Cyathulae 15-25 part, Pericarpium Zanthoxyli 15-25 part, Flos Celosiae Cristatae 10-20 part, Rhizoma Cyperi 6-18 part, Os Draconis 20-30 part, Flos Lonicerae 25-40 part, Rhizoma Coptidis 8-13 part, Radix Bupleuri 13-28 part and Flos Chrysanthemi Indici 15-25 part.
Foregoing Chinese medicinal formulae, preferred scheme is, is prepared from by the crude drug of following weight proportioning: Rhizoma Chuanxiong 25-35 part, Herba Alii fistulosi 4-6 part, Radix Cyathulae 18-23 part, Pericarpium Zanthoxyli 18-23 part, Flos Celosiae Cristatae 13-18 part, Rhizoma Cyperi 10-14 part, Os Draconis 23-28 part, Flos Lonicerae 30-35 part, Rhizoma Coptidis 9-11 part, Radix Bupleuri 18-20 part and Flos Chrysanthemi Indici 18-23 part.
Foregoing Chinese medicinal formulae, better preferred scheme is prepared from by the crude drug of following weight proportioning: Rhizoma Chuanxiong 30 parts, Herba Alii fistulosi 5 parts, Radix Cyathulae 20 parts, 20 parts, Pericarpium Zanthoxyli, Flos Celosiae Cristatae 15 parts, Rhizoma Cyperi 12 parts, Os Draconis 25 parts, Flos Lonicerae 32 parts, Rhizoma Coptidis 10 parts, Radix Bupleuri 19 parts and Flos Chrysanthemi Indici 20 parts.
According to the preparation method of the Chinese medicinal formulae for the treatment of chronic pelvic inflammatory disease noted earlier, step is as follows:
(1) first Rhizoma Chuanxiong, Pericarpium Zanthoxyli and Flos Chrysanthemi Indici are cleaned, break into the block of Pericarpium Zanthoxyli size, drain away the water, be placed in boiled hot water, constantly boiling 2-6 minute, make little fire heating into after 1-5 minute, after filtration, filtrate are cooled to 30-40 DEG C, are distributed into air-tight bottle and obtain external-use lotion;
(2) Os Draconis are broken into the block of coin-size, be placed in the upper big fire of iron plate and dry 20-30 minute, cool that to grind to form smalls stand-by;
(3) by Herba Alii fistulosi defoliation, Bulbus Allii Fistulosi is cut into the block of small rice grain size by knife, being placed in gauze, is pounded Herba Alii fistulosi mud ultraviolet sterilization 5-10 minute with rolling pin, stand-by;
(4) Chinese liquor of Radix Cyathulae, Flos Celosiae Cristatae, Rhizoma Cyperi, Flos Lonicerae, Rhizoma Coptidis and Radix Bupleuri 30-40 DEG C (preferably 35 DEG C) is placed in sealing and standing 1-3 days (preferably 2 days) in crock, be placed in the hot pot dryouied, little fire is fried to 10-20 minute, and taking-up cools, and it is stand-by to grind to form smalls;
(5) step (2)-(4) gains are together placed in marmite; add mixed material medicine gross weight 1-3 water doubly; intense fire is heated to boiling; continue after 3-5 minute (preferably 4 minutes); change slow fire boiling, the process Chinese medicine of decoction constantly stirs, in time becoming thick paste; cease fire, cool bottling and namely obtain oral thick paste.
Foregoing preparation method, preferred scheme is: step (1) is placed in boiled hot water, constantly boiling 3-5 minute (preferred, to be placed in boiled hot water, constantly boiling 4 minutes).
Foregoing preparation method, preferred scheme is: after step (1) filtrate is cooled to 33-38 DEG C, is distributed into air-tight bottle (preferred filtrate be cooled to 35 DEG C after, be distributed into air-tight bottle).
Foregoing preparation method, preferred scheme is: step (2) is placed in the upper big fire of iron plate and dries 23-28 minute (be preferably placed in the upper big fire of iron plate and dry 25 minutes).
Foregoing preparation method, preferred scheme is: step (3) Herba Alii fistulosi mud ultraviolet sterilization 7-9 minute (preferred Herba Alii fistulosi mud ultraviolet sterilization 8 minutes).
Foregoing preparation method, preferred scheme is: the little fire of step (4) is fried to 13-18 minute (preferred little fire was fried to 15 minutes).
Foregoing preparation method, preferred scheme is: step (5) adds mixed material medicine gross weight 1.5-2.5 water (preferably adding the water of mixed material medicine gross weight 2 times) doubly.
Using method: for making the present invention reach optimum therapeuticing effect, boiled water is washed open and is taken half an hour after breakfast, lunch and dinner for preparation and the thick paste that obtain, and each 5 grams 10 days is a course for the treatment of, the external-use lotion of gained, cleans pudendum position.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Rhizoma Chuanxiong: Rhizoma Chuanxiong is a kind of Chinese medicinal plant, is usually used in blood-activating and qi-promoting, wind-expelling pain-stopping, the pungent temperature of Rhizoma Chuanxiong is fragrant dry, walks and does not keep, can go loose, and the up mountain peak that reaches is pushed up; Enter blood system again, descendingly reach the sea of blood.Blood circulation promoting and blood stasis dispelling effect is extensive, the suitable various disease of stagnation of blood stasis; Wind-expelling pain-stopping, effectiveness is excellent, can control the diseases such as wind syndrome of head headache, rheumatic arthralgia.It is gas medicine in blood that former times people calls Rhizoma Chuanxiong, the functions such as pungent loose, the resolving depression of its residence of dangerous speech, sensible, pain relieving.
Herba Alii fistulosi: another name and thing grass, onion, dish primary, HUOCONG, the four seasons Herba Alii fistulosi.Flavor efficacy is pungent, and temperature, enters lung, stomach warp.Exterior-excess hollow, rise to fall more and lack, merit is specially dispersed and is activated yang, can expelling wind and cold pathogens, and diaphoresis expelling pathogenic factors from muscles, is used for the treatment of the mild of typhoid fever, cold and heat headache; Again can item, sharp key, relieving constipation, activate yang gas and loose YIN-cold, be used for the treatment of QI and blood cohesion, dizzy headache, QI stagnated by cold, abdominal distention is suffered from abdominal pain, and bladder qi dysfunction and dysuria etc.; In addition still tool removing toxic substances, hemostatic function.Energy activating yang to invigorate blood circulation, anthelmintic removing toxic substances, relieving the exterior syndrome by diaphoresis.Cure mainly the diseases such as anemofrigid cold mild, carbuncle sore tumefacting virus, dysentery faint pulse, cold coagulation stomachache, dysuria, have good therapeutical effect to flu, wind and cold, headache, YIN-cold stomachache, malnutrition due to parasitic infestation internal resistance, dysentery etc.1. antipyretic, eliminate the phlegm: the effective ingredient such as the external-use lotion of Herba Alii fistulosi, have and stimulate health sweat gland, reach the effect of diaphoresis heat radiation; Scallion oil stimulates upper respiratory tract, makes sticky expectorant be easy to bring up.2. facilitating digestion absorbs: Herba Alii fistulosi also has the effect stimulating body digestive juice secretion, can spleen benefiting and stimulating the appetite, appetite stimulator.3. antibacterial, antiviral 4. cancer-resisting.
Radix Cyathulae: Radix Cyathulae, has another name called Radix Achyranthis Bidentatae, turns knee joint, the full Radix Achyranthis Bidentatae in sky, all NIUJIAO etc.Root is cylindrical, surface near-white time fresh, taupe or brown color after dry.Produce the ground such as Sichuan, Yunnan, Guizhou.Root hyoscine, raw product have the effect of decline blood stasis removing and clots absorbing, ripe product invigorating the liver and kidney, strong waist knee joint.Sweet; Micro-hardship; Property is put down, and dispel the wind, dampness removing, stimulates the menstrual flow, and invigorates blood circulation.Dispelling the wind and dampness pathogens lumbocrural pain, foot flaccidity clonic spasm of the muscle, stranguria with blood, hematuria, women's amenorrhea, lump in the abdomen.For amenorrhea lump in the abdomen, retention of placenta, arthralgia, flaccidity of the lower limbs clonic spasm of the muscle, hematuria stranguria with blood, injury from falling down.
Pericarpium Zanthoxyli: Pericarpium Zanthoxyli: the traditional Chinese medical science is thought, Pericarpium Zanthoxyli is warm in nature, acrid in the mouth, has warming spleen and stomach for dispelling cold, stomach invigorating dehumidifying, pain relieving parasite killing, removing toxic substances are regulated the flow of vital energy, effect of antipruritic raw meat of dispelling; Can be used for treating food stagnation, stop pain of joint muscle, coldness and pain in the epigastrium caused by drink, singultus, vomiting, wind-cold damp pathogen, have loose bowels, dysentery, ascarid, the disease such as pudendal pruritus.Warming spleen and stomach for dispelling cold, dehumidifying, pain relieving, parasite killing, separates fish raw meat poison.Control food stagnation and stop drink, trusted subordinate's cold type of pain, vomiting, oh, cough gas Pericarpium Zanthoxyli is inverse, and anemofrigid-damp arthralgia, has loose bowels, dysentery, colic, toothache, ascariasis, enterobiasis, pudendal pruritus, skin ulcer scabies.
Flos Celosiae Cristatae: Flos Celosiae Cristatae formal name used at school, Chinese another name: chicken hair worn in a bun or coil flower, old next red, Flos Phragmitis cockscomb, a cockscomb, microcephaly's cockscomb, Fengxian-Taibai region, greatly cock flower, chicken angle root, red cockscomb.Sweet, puckery, cool.Return liver, large intestine channel.Astringing to arrest bleeding, leukorrhagia stopping, dysentery relieving.For spitting blood, metrorrhagia, has blood in stool, hemorrhoidal bleeding, leucorrhea with red and white discharge, and chronic dysentery is more than.
Rhizoma Cyperi: pungent micro-hardship is sweet, flat.To regulate the flow of vital energy resolving depression; Menstruction regulating and pain relieving; Antiabortive.Main distending pain over the hypochondrium; Mammary swelling is educated; Hernia pain; Menoxenia; Gastral cavity abdomen feeling of fullness pain; Belch acid regurgitation, vomiting and nausea; Abdominal pain during menstruation; Bleeding not during menses; Frequent fetal movement.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.
Os Draconis: base is former: for mammal in ancient times resembles the Skeletal Fossils of class, rhinoceros class, Hippocampal cortex, bovine, deer class etc.Composition: Os Draconis, mainly containing calcium carbonate and calcium phosphate, still contain ferrum, potassium, sodium, chlorine, sulfate radical etc.The property of medicine: puckery, sweet, flat.GUIXIN, liver, kidney, large intestine channel.Function cures mainly: tranquilizing mind, suppressing the hyperactive liver and subsiding YANG, restrains astringent or styptic treatment for spontaneous sweating.Cure mainly cardiopalmus, seized with terror swollen, insomnia, forgetful, infantile convulsion, demented, dizzy, spontaneous sweating, the seminal emission enuresis, bleeding not during menses, chronic diarrhea and dysentery, ulcer does not close up and eczema for a long time.Compatibility and incompatibility of drugs: the careful clothes of the excess-heat person of stagnating.
Flos Lonicerae: Flos Lonicerae, having another name called Radix Ophiopogonis " Flos Lonicerae " one comes from Compendium of Material Medica, owing to opening as white at the beginning of Flos Lonicerae, after transfer yellow to, hence obtain one's name Flos Lonicerae.Medical material Flos Lonicerae is Caprifoliaceae woodbine Radix Ophiopogonis and congener dry flower or is with the flower just opened.Flos Lonicerae is described as the good medicine of heat-clearing and toxic substances removing from ancient times.Its property sweet cold fragrance, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, fragrance thoroughly reaches and can be eliminating evil.Flos Lonicerae can dispelling wind-heat, also kind removing summer-heat blood poison, for various febrile disease, as fever of the body, dermexanthesis, sends out the diseases such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, equal Be very effective.
Rhizoma Coptidis: Rhizoma Coptidis is called: taste company, Rhizoma Coptidis, Rhizoma Coptidis, belong to Ranunculaceae, Coptis herbaceos perennial, phyllopodium is hesitated, hard papery, ovum shape triangle, and three totally cleave, central sliver ovum shape rhombus, pinniform drastic crack, and there is sharp sawtooth at edge, and the raw sliver in side does not wait 2 drastic cracks; The long 5-12cm of petiole.Heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.It is burning hot that Rhizoma Coptidis (processed with wine) is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tie mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.
Radix Bupleuri: another name ground is smoked, mountain dish, mushroom are careless, faggot.Nature and flavor are bitter, are slightly cold.Return liver, gallbladder meridian.There is reconciling superficies and interior, soothing the liver, effect of yang invigorating.For cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterine prolapse, menoxenia.
Flos Chrysanthemi Indici: Flos Chrysanthemi Indici is Compositae herbaceos perennial, and the capitate profile of Flos Chrysanthemi Indici is similar to Flos Chrysanthemi, wild in wild areas such as patana, Tian Bian, roadsides.Be good with yellow skin without stalk, complete, toil, the non-standard-sized sheet person of flower.Flos Chrysanthemi Indici cold nature, tool dispelling wind and heat pathogens, subduing swelling and detoxicating.Furuncle carbuncle, laryngopharynx swelling and pain, wind-fire acute conjunctivitis can be treated, the disease such as dizzy of having a headache.
Chinese medicinal formulae of the present invention meets the principle that disease treatment debated by Chinese medicine.The medical material selected is divided into thick paste for oral administration and external external-use lotion, inside and outside treat simultaneously, treatment is more comprehensive, and affected area administration is rapider, lasting medicine, take into account inside and outside belonging to, the migraine prescription for the treatment of both the principal and secondary aspects of a disease, has fabulous therapeutical effect to chronic pelvic inflammatory disease, not only there is good therapeutical effect to chronic pelvic inflammatory disease, very very effective in cure to trigeminal neuralgia, in addition, excellent results of the present invention also shows:
1,in selected materials Rhizoma Chuanxiong, Herba Alii fistulosi, Pericarpium Zanthoxyli, Rhizoma Coptidis and Flos Chrysanthemi Indici there is heat-clearing and toxic substances removing, blood stasis dispelling, invigorate blood circulation, effect of circulation of qi promoting, other crude drug have treatment antiinflammatory, pain relieving, calm the nerves, sensible effect, the crude drug of different efficacies is combined, serve heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, Xiao Disorder eliminating stagnation, promoting the circulation of QI to relieve pain, effect for the treatment of chronic pelvic inflammatory disease;
2,this prescription meets Chinese medicine principle and undergoing chronic pelvic inflammation body and mind feature completely, under the prerequisite of general principle, can have different prescription according to different crowd, and function is different.
3,medicine source is easy to get, and medical material is with low cost, can relieve patient ' s burden.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1the Chinese medicinal formulae for the treatment of chronic pelvic inflammatory disease, gets the raw materials ready (getting 20g for every part) by following weight parts: Rhizoma Chuanxiong 20 parts, Herba Alii fistulosi 3 parts, Radix Cyathulae 15 parts, 15 parts, Pericarpium Zanthoxyli, Flos Celosiae Cristatae 10 parts, Rhizoma Cyperi 6 parts, Os Draconis 20 parts, Flos Lonicerae 25 parts, Rhizoma Coptidis 8 parts, Radix Bupleuri 13 parts and Flos Chrysanthemi Indici 15 parts.
The preparation method of the Chinese medicinal formulae of above-mentioned treatment chronic pelvic inflammatory disease:
(1) first Rhizoma Chuanxiong, Pericarpium Zanthoxyli and Flos Chrysanthemi Indici are cleaned, break into the block of Pericarpium Zanthoxyli size, drain away the water, be placed in boiled hot water, constantly boiling 2 minutes, make little fire heating into after 1 minute, after filtration, filtrate are cooled to 30 DEG C, are distributed into air-tight bottle and obtain external-use lotion;
(2) Os Draconis are broken into the block of coin-size, be placed in the upper big fire of iron plate and dry 20 minutes, cool that to grind to form smalls stand-by;
(3) by Herba Alii fistulosi defoliation, Bulbus Allii Fistulosi is cut into the block of small rice grain size by knife, being placed in gauze, is pounded Herba Alii fistulosi mud ultraviolet sterilization 5 minutes with rolling pin, stand-by;
(4) Flos Celosiae Cristatae, Rhizoma Cyperi, Flos Lonicerae, Rhizoma Coptidis and the Radix Bupleuri Chinese liquor of 30 DEG C to be placed in crock sealing and standing 1 day, be placed in the hot pot dryouied, little fire was fried to 10 minutes, and taking-up cools, and it is stand-by to grind to form smalls;
(5) be together placed in marmite by step (2)-(4) gains, add the water of mixed material medicine gross weight 1 times, intense fire is heated to boiling; continue after 3 minutes, change slow fire boiling, the process Chinese medicine of decoction constantly stirs; in time becoming thick paste, cease fire, cool bottling and namely obtain oral thick paste.
typical case one:liu XX, female, 29 years old, Jinan, Shandong Province people from Jiyang.Clinical psoas muscle portion acid distending pain, aggravate before and after sexual intercourse, defecation and menstruation, irregular menstruation, dysmenorrhea, companion's frequent micturition, gynecologial examination adnexa thickens, and uterine activity is limited, and pelvic cavity has hydrops, surpasses inspection be diagnosed as chronic pelvic inflammatory disease through B.When patient examines: the experience saying twice artificial abortion, post-abortion does not nurse one's health, and doctor, by its inquiry and observation, is diagnosed as chronic pelvic inflammatory disease.
Give the oral embodiment of the present invention 1 gained prescription and with the use of the embodiment of the present invention 1 gained external-use lotion, after 5 days, patient's self-induction pain is no longer obvious, and after continuing to have taken 1 course for the treatment of, patient pain feels disappearance, sexual intercourse, defecation and menstruation recovery are normal, leucorrhea is normal, and urine and stool is normal, continues again to take 1 course for the treatment of, gynecologial examination uterine activity recovers normal, and in pelvic cavity, hydrops disappears.
embodiment 2the Chinese medicinal formulae for the treatment of chronic pelvic inflammatory disease, gets the raw materials ready (getting 20g for every part) by following weight parts: Rhizoma Chuanxiong 40 parts, Herba Alii fistulosi 7 parts, Radix Cyathulae 25 parts, 25 parts, Pericarpium Zanthoxyli, Flos Celosiae Cristatae 20 parts, Rhizoma Cyperi 18 parts, Os Draconis 30 parts, Flos Lonicerae 40 parts, Rhizoma Coptidis 13 parts, Radix Bupleuri 28 parts and Flos Chrysanthemi Indici 25 parts.
The preparation method of the Chinese medicinal formulae for the treatment of chronic pelvic inflammatory disease is:
(1) first Rhizoma Chuanxiong, Pericarpium Zanthoxyli and Flos Chrysanthemi Indici are cleaned, break into the block of Pericarpium Zanthoxyli size, drain away the water, be placed in boiled hot water, constantly boiling 6 minutes, make little fire heating into after 5 minutes, after filtration, filtrate are cooled to 40 DEG C, are distributed into air-tight bottle and obtain external-use lotion;
(2) Os Draconis are broken into the block of coin-size, be placed in the upper big fire of iron plate and dry 30 minutes, cool that to grind to form smalls stand-by;
(3) by Herba Alii fistulosi defoliation, Bulbus Allii Fistulosi is cut into the block of small rice grain size by knife, being placed in gauze, is pounded Herba Alii fistulosi mud ultraviolet sterilization 10 minutes with rolling pin, stand-by;
(4) Flos Celosiae Cristatae, Rhizoma Cyperi, Flos Lonicerae, Rhizoma Coptidis and the Radix Bupleuri Chinese liquor of 40 DEG C to be placed in crock sealing and standing 3 days, be placed in the hot pot dryouied, little fire was fried to 20 minutes, and taking-up cools, and it is stand-by to grind to form smalls;
(5) be together placed in marmite by step (2)-(4) gains, add the water of mixed material medicine gross weight 3 times, intense fire is heated to boiling; continue after 5 minutes, change slow fire boiling, the process Chinese medicine of decoction constantly stirs; in time becoming thick paste, cease fire, cool bottling and namely obtain oral thick paste.
embodiment 3the Chinese medicinal formulae for the treatment of chronic pelvic inflammatory disease, gets the raw materials ready (getting 20g for every part) by following weight parts: Rhizoma Chuanxiong 25 parts, Herba Alii fistulosi 4 parts, Radix Cyathulae 18 parts, 18 parts, Pericarpium Zanthoxyli, Flos Celosiae Cristatae 13 parts, Rhizoma Cyperi 10 parts, Os Draconis 23 parts, Flos Lonicerae 30 parts, Rhizoma Coptidis 9 parts, Radix Bupleuri 18 parts and Flos Chrysanthemi Indici 18 parts.
The preparation method of the Chinese medicinal formulae for the treatment of chronic pelvic inflammatory disease is:
(1) first Rhizoma Chuanxiong, Pericarpium Zanthoxyli and Flos Chrysanthemi Indici are cleaned, break into the block of Pericarpium Zanthoxyli size, drain away the water, be placed in boiled hot water, constantly boiling 3 minutes, make little fire heating into after 2 minutes, after filtration, filtrate are cooled to 33 DEG C, are distributed into air-tight bottle and obtain external-use lotion; ;
(2) Os Draconis are broken into the block of coin-size, be placed in the upper big fire of iron plate and dry 23 minutes, cool that to grind to form smalls stand-by;
(3) by Herba Alii fistulosi defoliation, Bulbus Allii Fistulosi is cut into the block of small rice grain size by knife, being placed in gauze, is pounded Herba Alii fistulosi mud ultraviolet sterilization 7 minutes with rolling pin, stand-by;
(4) Flos Celosiae Cristatae, Rhizoma Cyperi, Flos Lonicerae, Rhizoma Coptidis and the Radix Bupleuri Chinese liquor of 33 DEG C to be placed in crock sealing and standing 1.5 days, be placed in the hot pot dryouied, little fire was fried to 13 minutes, and taking-up cools, and it is stand-by to grind to form smalls;
(5) be together placed in marmite by step (2)-(4) gains, add the water of mixed material medicine gross weight 1.5 times, intense fire is heated to boiling; continue after 3.5 minutes, change slow fire boiling, the process Chinese medicine of decoction constantly stirs; in time becoming thick paste, cease fire, cool bottling and namely obtain oral thick paste.
typical case two:field XX, female 35 years old, Jinan, Shandong Province personage, cadre at their posts, patient's readme:, companion psoas muscle portion acid distending pain, aggravate before and after fatigue, sexual intercourse, defecation and menstruation, leucorrhea amount is many, irregular menstruation, frequent micturition, gynecologial examination adnexa thickens, uterine activity is limited, and pelvic cavity has hydrops, surpasses inspection be diagnosed as chronic pelvic inflammatory disease through B.Listen friend to say Chinese medicinal formulae of the present invention treatment chronic pelvic inflammatory disease effect very good in November, 2013, just buy 4 courses for the treatment of.
Take the embodiment of the present invention 3 gained Chinese medicinal formulae and with the use of embodiment 3 gained external-use lotion, after 1 course for the treatment of, patient's sensation pain when falling ill is so inviolent, after continuing to take 2 courses for the treatment of, patient pain feels disappearance, sexual intercourse, defecation and menstruation recovery are normal, and leucorrhea is normal, and urine and stool is normal, gynecologial examination uterine activity recovers normal, and in pelvic cavity, hydrops disappears.
embodiment 4the Chinese medicinal formulae for the treatment of chronic pelvic inflammatory disease, gets the raw materials ready (getting 20g for every part) by following weight parts: Rhizoma Chuanxiong 35 parts, Herba Alii fistulosi 6 parts, Radix Cyathulae 23 parts, 23 parts, Pericarpium Zanthoxyli, Flos Celosiae Cristatae 18 parts, Rhizoma Cyperi 14 parts, Os Draconis 28 parts, Flos Lonicerae 35 parts, Rhizoma Coptidis 11 parts, Radix Bupleuri 20 parts and Flos Chrysanthemi Indici 23 parts.
The preparation method of the Chinese medicinal formulae for the treatment of chronic pelvic inflammatory disease is:
(1) first Rhizoma Chuanxiong, Pericarpium Zanthoxyli and Flos Chrysanthemi Indici are cleaned, break into the block of Pericarpium Zanthoxyli size, drain away the water, be placed in boiled hot water, constantly boiling 5 minutes, make little fire heating into after 4 minutes, after filtration, filtrate are cooled to 38 DEG C, are distributed into air-tight bottle and obtain external-use lotion;
(2) Os Draconis are broken into the block of coin-size, be placed in the upper big fire of iron plate and dry 28 minutes, cool that to grind to form smalls stand-by;
(3) by Herba Alii fistulosi defoliation, Bulbus Allii Fistulosi is cut into the block of small rice grain size by knife, being placed in gauze, is pounded Herba Alii fistulosi mud ultraviolet sterilization 9 minutes with rolling pin, stand-by;
(4) Flos Celosiae Cristatae, Rhizoma Cyperi, Flos Lonicerae, Rhizoma Coptidis and the Radix Bupleuri Chinese liquor of 38 DEG C to be placed in crock sealing and standing 2.5 days, be placed in the hot pot dryouied, little fire was fried to 18 minutes, and taking-up cools, and it is stand-by to grind to form smalls;
(5) be together placed in marmite by step (2)-(4) gains, add the water of mixed material medicine gross weight 2.5 times, intense fire is heated to boiling; continue after 4.5 minutes, change slow fire boiling, the process Chinese medicine of decoction constantly stirs; in time becoming thick paste, cease fire, cool bottling and namely obtain oral thick paste.
embodiment 5the Chinese medicinal formulae for the treatment of chronic pelvic inflammatory disease, gets the raw materials ready (getting 20g for every part) by following weight parts: Rhizoma Chuanxiong 30 parts, Herba Alii fistulosi 5 parts, Radix Cyathulae 20 parts, 20 parts, Pericarpium Zanthoxyli, Flos Celosiae Cristatae 15 parts, Rhizoma Cyperi 12 parts, Os Draconis 25 parts, Flos Lonicerae 32 parts, Rhizoma Coptidis 10 parts, Radix Bupleuri 19 parts and Flos Chrysanthemi Indici 20 parts.
The preparation method of the Chinese medicinal formulae for the treatment of chronic pelvic inflammatory disease is:
(1) first Rhizoma Chuanxiong, Pericarpium Zanthoxyli and Flos Chrysanthemi Indici are cleaned, break into the block of Pericarpium Zanthoxyli size, drain away the water, be placed in boiled hot water, constantly boiling 4 minutes, make little fire heating into after 3 minutes, after filtration, filtrate are cooled to 35 DEG C, are distributed into air-tight bottle and obtain external-use lotion; ;
(2) Os Draconis are broken into the block of coin-size, be placed in the upper big fire of iron plate and dry 25 minutes, cool that to grind to form smalls stand-by;
(3) by Herba Alii fistulosi defoliation, Bulbus Allii Fistulosi is cut into the block of small rice grain size by knife, being placed in gauze, is pounded Herba Alii fistulosi mud ultraviolet sterilization 8 minutes with rolling pin, stand-by;
(4) Flos Celosiae Cristatae, Rhizoma Cyperi, Flos Lonicerae, Rhizoma Coptidis and the Radix Bupleuri Chinese liquor of 35 DEG C to be placed in crock sealing and standing 2 days, be placed in the hot pot dryouied, little fire was fried to 15 minutes, and taking-up cools, and it is stand-by to grind to form smalls;
(5) be together placed in marmite by step (2)-(4) gains, add the water of mixed material medicine gross weight 2 times, intense fire is heated to boiling; continue after 4 minutes, change slow fire boiling, the process Chinese medicine of decoction constantly stirs; in time becoming thick paste, cease fire, cool bottling and namely obtain oral thick paste.
test example 1the clinical practice of the Chinese medicinal formulae of embodiment 5 gained treatment chronic pelvic inflammatory disease: patient 400 example choosing chronic pelvic inflammatory disease in 10 hospitals, before test 1 week, Continuous Observation is carried out to this crowd, record symptom and change, be divided into two groups at random, experimental group and matched group, experimental group takes embodiment 5 products obtained therefrom, and matched group takes other medicine (conventional medication such as first nitre file sheet, red astragalus root for removing blood stasis capsule etc.).Curative effect situation criterion: cure: take gained tablet of the present invention and after coordinating gained external-use lotion of the present invention, malaise symptoms has clear improvement, and pain, scratchiness disappear substantially, leucorrhea is normal, and vagina flows out without secretions; Effective: to take gained tablet of the present invention and after coordinating gained external-use lotion of the present invention, malaise symptoms makes moderate progress; Invalid: after taking this product, malaise symptoms is unchanged.Result is as shown in table 1.
Table 1:
Gained Chinese medicinal formulae effective percentage of the present invention is up to 99%, and cure rate is up to 97%, and successful is better than experimental group, and takes product of the present invention 5 days, and malaise symptoms improves, and pain, scratchiness alleviate to some extent, and vagina flows out without secretions; Take 8 days, malaise symptoms improves or disappears; Take 12 days, malaise symptoms improves or disappears, and ultrasound diagnosis inspection display is normal, and some patients self-induction is fully recovered.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. treat a Chinese medicinal formulae for chronic pelvic inflammatory disease, be prepared from by the crude drug of following weight proportioning: Rhizoma Chuanxiong 20-40 part, Herba Alii fistulosi 3-7 part, Radix Cyathulae 15-25 part, Pericarpium Zanthoxyli 15-25 part, Flos Celosiae Cristatae 10-20 part, Rhizoma Cyperi 6-18 part, Os Draconis 20-30 part, Flos Lonicerae 25-40 part, Rhizoma Coptidis 8-13 part, Radix Bupleuri 13-28 part and Flos Chrysanthemi Indici 15-25 part.
2. Chinese medicinal formulae according to claim 1, preferred scheme is, is prepared from by the crude drug of following weight proportioning: Rhizoma Chuanxiong 25-35 part, Herba Alii fistulosi 4-6 part, Radix Cyathulae 18-23 part, Pericarpium Zanthoxyli 18-23 part, Flos Celosiae Cristatae 13-18 part, Rhizoma Cyperi 10-14 part, Os Draconis 23-28 part, Flos Lonicerae 30-35 part, Rhizoma Coptidis 9-11 part, Radix Bupleuri 18-20 part and Flos Chrysanthemi Indici 18-23 part.
3. Chinese medicinal formulae according to claim 1, better preferred scheme is prepared from by the crude drug of following weight proportioning: Rhizoma Chuanxiong 30 parts, Herba Alii fistulosi 5 parts, Radix Cyathulae 20 parts, 20 parts, Pericarpium Zanthoxyli, Flos Celosiae Cristatae 15 parts, Rhizoma Cyperi 12 parts, Os Draconis 25 parts, Flos Lonicerae 32 parts, Rhizoma Coptidis 10 parts, Radix Bupleuri 19 parts and Flos Chrysanthemi Indici 20 parts.
4., according to the preparation method of the Chinese medicinal formulae according to the arbitrary described treatment chronic pelvic inflammatory disease of claim 1-3, step is as follows:
(1) first Rhizoma Chuanxiong, Pericarpium Zanthoxyli and Flos Chrysanthemi Indici are cleaned, break into the block of Pericarpium Zanthoxyli size, drain away the water, be placed in boiled hot water, constantly boiling 2-6 minute, make little fire heating into after 1-5 minute, after filtration, filtrate are cooled to 30-40 DEG C, are distributed into air-tight bottle and obtain external-use lotion;
(2) Os Draconis are broken into the block of coin-size, be placed in the upper big fire of iron plate and dry 20-30 minute, cool that to grind to form smalls stand-by;
(3) by Herba Alii fistulosi defoliation, Bulbus Allii Fistulosi is cut into the block of small rice grain size by knife, being placed in gauze, is pounded Herba Alii fistulosi mud ultraviolet sterilization 5-10 minute with rolling pin, stand-by;
(4) Chinese liquor of Radix Cyathulae, Flos Celosiae Cristatae, Rhizoma Cyperi, Flos Lonicerae, Rhizoma Coptidis and Radix Bupleuri 30-40 DEG C (preferably 35 DEG C) is placed in sealing and standing 1-3 days (preferably 2 days) in crock, be placed in the hot pot dryouied, little fire is fried to 10-20 minute, and taking-up cools, and it is stand-by to grind to form smalls;
(5) step (2)-(4) gains are together placed in marmite; add mixed material medicine gross weight 1-3 water doubly; intense fire is heated to boiling; continue after 3-5 minute (preferably 4 minutes); change slow fire boiling, the process Chinese medicine of decoction constantly stirs, in time becoming thick paste; cease fire, cool bottling and namely obtain oral thick paste.
5. preparation method according to claim 4, is characterized in that: be placed in boiled hot water, constantly boiling 3-5 minute (preferred, to be placed in boiled hot water, constantly boiling 4 minutes).
6. preparation method according to claim 4, is characterized in that: after step (1) fluid is cooled to 33-38 DEG C, is distributed into air-tight bottle (preferred oil liquid be cooled to 35 DEG C after, be distributed into air-tight bottle).
7. preparation method according to claim 4, is characterized in that: step (2) is placed in the upper big fire of iron plate and dries 23-28 minute (be preferably placed in the upper big fire of iron plate and dry 25 minutes).
8. preparation method according to claim 4, is characterized in that: step (3) Herba Alii fistulosi mud ultraviolet sterilization 7-9 minute (preferred Herba Alii fistulosi mud ultraviolet sterilization 8 minutes).
9. preparation method according to claim 4, is characterized in that: the little fire of step (4) is fried to 13-18 minute (preferred little fire was fried to 15 minutes).
10. preparation method according to claim 4, is characterized in that: step (5) adds mixed material medicine gross weight 1.5-2.5 water (preferably adding the water of mixed material medicine gross weight 2 times) doubly.
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Application publication date: 20150325 |