CN103201611B - 用于流动型颗粒分析仪的双反馈真空流动技术 - Google Patents

用于流动型颗粒分析仪的双反馈真空流动技术 Download PDF

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Publication number
CN103201611B
CN103201611B CN201180052384.6A CN201180052384A CN103201611B CN 103201611 B CN103201611 B CN 103201611B CN 201180052384 A CN201180052384 A CN 201180052384A CN 103201611 B CN103201611 B CN 103201611B
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flow
fluid
sample
resistance
pressure drop
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CN103201611A (zh
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D·弗兰
P·O·诺顿
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Becton Dickinson and Co
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G01N15/1409—Handling samples, e.g. injecting samples
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/0318—Processes
    • Y10T137/0324—With control of flow by a condition or characteristic of a fluid
    • Y10T137/0379—By fluid pressure

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  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • Health & Medical Sciences (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Optical Measuring Cells (AREA)
  • Fluid Mechanics (AREA)
  • Engineering & Computer Science (AREA)
  • Automation & Control Theory (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CN201180052384.6A 2010-10-29 2011-10-24 用于流动型颗粒分析仪的双反馈真空流动技术 Active CN103201611B (zh)

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US40799010P 2010-10-29 2010-10-29
US61/407,990 2010-10-29
PCT/US2011/057445 WO2012058142A1 (en) 2010-10-29 2011-10-24 Dual feedback vacuum fluidics for a flow-type particle analyzer

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CN103201611A CN103201611A (zh) 2013-07-10
CN103201611B true CN103201611B (zh) 2015-03-11

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US (2) US8528427B2 (enExample)
EP (1) EP2633283B1 (enExample)
JP (1) JP5771696B2 (enExample)
CN (1) CN103201611B (enExample)
AU (1) AU2011320713B2 (enExample)
ES (1) ES2732355T3 (enExample)
SG (1) SG189532A1 (enExample)
WO (1) WO2012058142A1 (enExample)
ZA (1) ZA201302955B (enExample)

Families Citing this family (107)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5138223B2 (ja) 2003-10-30 2013-02-06 サイトノーム エスティー リミテッド ライアビリティー カンパニー 流体力学的多層シースフロー構造
CA2764522C (en) * 2009-07-02 2015-09-15 The Governors Of The University Of Alberta Particle classifier
EP2545357B1 (en) * 2010-03-10 2021-06-02 Beckman Coulter, Inc. Generating pulse parameters in a particle analyzer
WO2014085585A1 (en) * 2012-11-29 2014-06-05 Cytoflow, Llc Fluidic system and method
EP4220124A1 (en) 2013-03-14 2023-08-02 Cytonome/ST, LLC Hydrodynamic focusing apparatus and methods
KR102095617B1 (ko) 2013-03-15 2020-03-31 아이리스 인터내셔널 인크. 혈액 샘플에서의 입자 분석을 위한 오토포커스 시스템 및 방법
US9372143B2 (en) * 2013-05-15 2016-06-21 Captl Llc Scanning image flow cytometer
WO2015061216A1 (en) * 2013-10-21 2015-04-30 Cytoflow, Llc Cytometer flowcell
CN103837462B (zh) * 2014-03-03 2016-10-05 中国科学院苏州生物医学工程技术研究所 一种小型流式细胞仪液路系统
JP5873126B2 (ja) * 2014-04-04 2016-03-01 日本電信電話株式会社 送液方法および送液システム
ES2954937T3 (es) 2014-12-04 2023-11-27 Becton Dickinson Co Sistemas de clasificación de células por citometría de flujo y métodos de uso de los mismos
US9709769B2 (en) 2014-12-10 2017-07-18 Becton, Dickinson And Company Methods for optically aligning light collection components and optically aligned light collection systems thereof
US10900885B2 (en) 2014-12-19 2021-01-26 Captl Llc Flow cytometry using hydrodynamically planar flow
ES2987551T3 (es) 2015-02-18 2024-11-15 Becton Dickinson Co Sistemas de detección óptica y métodos de uso de los mismos
EP3311135B1 (en) 2015-06-17 2023-11-01 Becton, Dickinson and Company Optical detector scatter cap assembly having a removable scatter bar and methods of using the same
US10036698B2 (en) 2015-06-19 2018-07-31 Captl Llc Time-sequential cytometry
JP6856635B2 (ja) 2015-10-13 2021-04-07 オメガ バイオシステムズ インコーポレイテッド マルチモードの蛍光撮像フローサイトメトリシステム
WO2017156034A1 (en) 2016-03-10 2017-09-14 Becton, Dickinson And Company Methods of evaluating a cellular sample for her-2/neu expression and compositions for practicing the same
AU2017234815B2 (en) 2016-03-17 2022-11-03 Becton, Dickinson And Company Cell sorting using a high throughput fluorescence flow cytometer
US11408812B2 (en) 2016-04-22 2022-08-09 Becton, Dickinson And Company High density deposition for array production
KR102381176B1 (ko) 2016-05-12 2022-04-01 비디 바이오사이언시스 개선된 이미지 해상도를 갖는 형광 이미징 유세포 분석법
US10006852B2 (en) 2016-09-13 2018-06-26 Becton, Dickinson And Company Flow cytometer with optical equalization
CN109073530B (zh) 2016-10-03 2022-04-26 贝克顿·迪金森公司 用于确定流式细胞仪中的流体流的液滴延迟的方法和系统
CN110234442A (zh) * 2016-11-19 2019-09-13 厦泰生物科技公司 具有步进流量控制阀的流式细胞术系统
US10436697B2 (en) * 2016-11-19 2019-10-08 Cytek Biosciences, Inc. Flow cytometery system with fluidics control system
EP3555630B1 (en) 2016-12-14 2023-05-31 Becton, Dickinson and Company Methods and compositions for obtaining a tuberculosis assessment in a subject
JP7058662B2 (ja) 2017-02-08 2022-04-22 ベクトン・ディキンソン・アンド・カンパニー 乾燥色素試薬装置、ならびにその製造及び使用方法
JP7173978B2 (ja) 2017-02-27 2022-11-17 ベクトン・ディキンソン・アンド・カンパニー 光検出システム及びその使用方法
US10613020B2 (en) * 2017-08-10 2020-04-07 The Boeing Company Burr detection systems and methods
US10801617B2 (en) 2018-01-05 2020-10-13 Cnh Industrial America Llc Propel system with active pump displacement control for balancing propel pump pressures in agricultural vehicles
SG11202006481YA (en) 2018-01-23 2020-08-28 Becton Dickinson Co Systems for dynamic light detection obscuration and methods for using thereof
WO2019191482A1 (en) 2018-03-30 2019-10-03 Becton, Dickinson And Company Water-soluble polymeric dyes having pendant chromophores
WO2019209713A1 (en) 2018-04-27 2019-10-31 Becton, Dickinson And Company Collection systems for flow cytometrically sorted samples and methods of using the same
JP7416729B2 (ja) 2018-06-19 2024-01-17 ベクトン・ディキンソン・アンド・カンパニー 検出器アレイのための可変多重化スイッチ、システム、およびその使用方法
CN112771365B (zh) 2018-06-28 2024-07-09 贝克顿·迪金森公司 集成式前置放大光检测系统及其使用方法
WO2020036730A1 (en) * 2018-08-15 2020-02-20 Becton, Dickinson And Company Flowrate and vacuum controlled fluid management system for a flow type particle analyzer
WO2020047468A1 (en) 2018-08-30 2020-03-05 Becton, Dickinson And Company Characterization and sorting for particle analyzers
CN109357991B (zh) * 2018-09-27 2020-05-26 清华大学 一种免标记原理的质谱流式细胞进样与离子化装置
US11035776B2 (en) 2018-10-30 2021-06-15 Becton, Dickinson And Company Particle sorting module with alignment window, systems and methods of use thereof
US11237093B2 (en) 2018-12-10 2022-02-01 Bio-Rad Laboratories, Inc. External fluidics system for flow cytometer
AU2019416121B2 (en) 2018-12-28 2025-03-13 Becton, Dickinson And Company Methods for spectrally resolving fluorophores of a sample and systems for same
EP3921622A4 (en) 2019-02-08 2022-11-09 Becton, Dickinson and Company DECISION MODULES FOR SORTING DROPLET, SYSTEMS AND METHODS OF USE THEREOF
CN119845832A (zh) 2019-03-22 2025-04-18 贝克顿·迪金森公司 使用射频多路复用激发数据对荧光成像进行光谱解混
CN113544490B (zh) 2019-03-29 2024-07-02 贝克顿·迪金森公司 用于颗粒辨别的参数
CN111796111B (zh) * 2019-04-08 2025-11-21 爱科来株式会社 送液方法和分析装置
JP7175231B2 (ja) * 2019-04-08 2022-11-18 アークレイ株式会社 検体の分析方法及び検体の分析装置
JP7312135B2 (ja) * 2019-04-08 2023-07-20 アークレイ株式会社 送液方法及び分析装置
JP7504127B2 (ja) 2019-05-14 2024-06-21 ベクトン・ディキンソン・アンド・カンパニー イメージングフローサイトメトリーのための位相キャリブレーション
IL287195B2 (en) 2019-05-30 2025-07-01 Becton Dickinson Co Phase correction of multiplexed radio frequency signals
EP3997439A4 (en) 2019-07-10 2023-07-19 Becton, Dickinson and Company RECONFIGURABLE INTEGRATED CIRCUITS TO ADJUST CELL SORTING CLASSIFICATION
WO2021055732A1 (en) * 2019-09-20 2021-03-25 Kansas State University Research Foundation Methods and apparatus for contactless orthographic imaging of aerosol particles
WO2021101692A1 (en) 2019-11-20 2021-05-27 Becton, Dickinson And Company A light detection module with adjustable sensitivity
WO2021127364A1 (en) 2019-12-20 2021-06-24 Becton, Dickinson And Company Methods for quantitating extra-cellular vesicle surface markers, and compositions for practicing the same
CN115176139A (zh) 2020-01-31 2022-10-11 贝克顿·迪金森公司 用于调整训练门以适应流式细胞仪数据的方法和系统
EP4100720A4 (en) 2020-02-07 2023-07-26 Becton, Dickinson and Company Clustered wavelength division light detection systems and methods of using the same
US11709125B2 (en) 2020-02-19 2023-07-25 Becton, Dickinson And Company Strobed laser excitation systems and methods of use thereof
US11592386B2 (en) 2020-02-26 2023-02-28 Becton, Dickinson And Company Light detection systems having a secondary light scatter detector and methods for using same
EP4111169A4 (en) 2020-02-27 2023-08-09 Becton, Dickinson and Company METHODS FOR IDENTIFYING SATURATED DATA SIGNALS IN CELL SORTING AND RELATED SYSTEMS
EP4121737A4 (en) 2020-03-17 2023-08-09 Becton, Dickinson and Company GAIN ADAPTED AMPLIFIERS FOR LIGHT DETECTION
WO2021211259A1 (en) 2020-04-16 2021-10-21 Becton, Dickinson And Company Systems for light detection array multiplexing and methods for same
CN115735111A (zh) 2020-04-28 2023-03-03 贝克顿·迪金森公司 用于对独特表型进行索引分选的方法及用于其的系统
US11879827B2 (en) 2020-04-29 2024-01-23 Becton, Dickinson And Company Methods for modulation and synchronous detection in a flow cytometer and systems for same
WO2021225736A1 (en) 2020-05-05 2021-11-11 Becton, Dickinson And Company Methods for determining detector gain in a flow cytometer
US11674879B2 (en) 2020-05-06 2023-06-13 Becton, Dickinson And Company Methods and systems for characterizing spillover spreading in flow cytometer data
WO2021236339A1 (en) 2020-05-18 2021-11-25 Becton, Dickinson And Company Resolution indices for detecting heterogeneity in data and methods of use thereof
US11867605B2 (en) 2020-06-19 2024-01-09 Becton, Dickinson And Company Flow cytometer with adjustable positional offset sort deflection plates and methods of using the same
US11754487B2 (en) 2020-06-24 2023-09-12 Becton, Dickinson And Company Flow cytometric droplet dispensing systems and methods for using the same
EP4610627A1 (en) 2020-06-26 2025-09-03 Becton Dickinson and Company Dual excitation beams for irradiating a sample in a flow stream and methods for using same
US11965813B2 (en) 2020-08-03 2024-04-23 Cytek Biosciences, Inc. Methods and apparatus for central source pressure-based cytometer fluidics system
JP7739421B2 (ja) 2020-09-22 2025-09-16 ベクトン・ディキンソン・アンド・カンパニー フローサイトメータにおけるベースラインノイズの連続測定方法およびそのためのシステム
JP2023549475A (ja) 2020-10-20 2023-11-27 ベクトン・ディキンソン・アンド・カンパニー 傾斜ビーム成形光学部品を含むフローサイトメータ、及びフローサイトメータを使用する方法
CN116583735A (zh) 2020-10-30 2023-08-11 贝克顿·迪金森公司 用于表征和编码光检测系统的方法和系统
US12306087B2 (en) 2020-11-19 2025-05-20 Becton, Dickinson And Company Method for optimal scaling of cytometry data for machine learning analysis and systems for same
CN116897281A (zh) 2021-01-13 2023-10-17 贝克顿·迪金森公司 包括光收集增强器的流式细胞仪及其使用方法
EP4281751A4 (en) 2021-01-25 2024-07-31 Becton, Dickinson and Company METHOD AND SYSTEMS FOR DETERMINING FALL DELAY USING DIFFUSION SIGNALS IN SPATIALLY SEPARATE LASERS
CN214895849U (zh) 2021-01-28 2021-11-26 贝克曼库尔特生物科技（苏州）有限公司 气泡检测装置和样本处理仪
US11994458B2 (en) 2021-02-04 2024-05-28 Becton, Dickinson And Company Integrated light interrogation modules and methods of use thereof
US20220268688A1 (en) 2021-02-05 2022-08-25 Cytek Biosciences, Inc. Integrated compact cell sorter
US12379301B2 (en) 2021-03-24 2025-08-05 Becton, Dickinson And Company Closed-system sorting flow cytometer adapters and methods of use thereof
WO2022225597A1 (en) * 2021-04-23 2022-10-27 Becton, Dickinson And Company Fluid management system for an analyzer and/or sorter type flow type particle analyzer
EP4337933A4 (en) 2021-05-14 2024-10-23 Becton, Dickinson and Company LIGHT DETECTION SYSTEMS BY SPECTRAL DISCRIMINATION AND METHODS OF USE THEREOF
US12135274B2 (en) 2021-08-10 2024-11-05 Becton, Dickinson And Company Outlet fittings for reducing bubbles at the interface with a flow cell, and flow cytometers and methods using the same
US12467845B2 (en) 2021-08-10 2025-11-11 Becton, Dickinson And Company Clamps for operably coupling an optical component to a mounting block, and methods and systems for using the same
KR20240088899A (ko) 2021-09-21 2024-06-20 벡톤 디킨슨 앤드 컴퍼니 베이스라인 복원 회로
WO2023091351A1 (en) 2021-11-17 2023-05-25 Becton, Dickinson And Company Methods for dynamic real-time adjustment of a data acquisition parameter in a flow cytometer
US20230160807A1 (en) 2021-11-24 2023-05-25 Becton, Dickinson And Company Integrated Flow Cytometry Data Quality Control
CN114594040B (zh) * 2022-03-23 2025-01-03 青岛瑞斯凯尔生物科技股份有限公司 一种流式细胞仪及其工作方法
EP4537076A4 (en) * 2022-06-06 2025-07-23 Becton Dickinson Co FLUID RESISTANCE UNITS, FLOW CYTOMETERS AND METHODS USING THEM
US20240312191A1 (en) 2023-03-14 2024-09-19 Becton, Dickinson And Company Methods for determining image filters for classifying particles of a sample and systems and methods for using same
US20240344983A1 (en) 2023-03-30 2024-10-17 Becton, Dickinson And Company Methods and systems for visualizing spectral signatures
CN121014085A (zh) 2023-04-13 2025-11-25 贝克顿迪金森公司 分子诊断信号实时分类方法
EP4454548A1 (en) * 2023-04-25 2024-10-30 Koninklijke Philips N.V. Air flow control for hemodynamic measurement cuff
US20240377307A1 (en) 2023-05-09 2024-11-14 Becton, Dickinson And Company Methods and systems for classifying analyte data into clusters
US20240377311A1 (en) 2023-05-09 2024-11-14 Becton, Dickinson And Company Methods for image-based detection and sorting and systems for same
US20240377325A1 (en) 2023-05-09 2024-11-14 Becton, Dickinson And Company Methods for assessing cell mitochondrial morphology and systems for same
US20250085212A1 (en) 2023-09-07 2025-03-13 Becton, Dickinson And Company Integrated Optofluidic Interrogation Modules, Flow Cytometers Including the Same, and Methods of Use Thereof
US20250137905A1 (en) 2023-10-27 2025-05-01 Becton, Dickinson And Company Fluid Supply Systems Having a Flow Control Circuit and Single Fluidic Connection, and Methods of Use Thereof
US20250237657A1 (en) 2024-01-18 2025-07-24 Becton, Dickinson And Company Methods for spectrally resolving fluorophores of a sample by generalized least squares and systems for same
US20250244333A1 (en) 2024-01-31 2025-07-31 Becton, Dickinson And Company Cell viability compensation (cvc) beads for flow cytometry applications and methods of using the same
US20250297940A1 (en) 2024-03-25 2025-09-25 Becton, Dickinson And Company Methods and systems for classifying analyte data
US20250308080A1 (en) 2024-04-02 2025-10-02 Becton, Dickinson And Company Methods for label-free cell sorting and systems for same
US20250314573A1 (en) 2024-04-05 2025-10-09 Becton, Dickinson And Company Gate/population naming in flow cytometry data analysis based on geometry and data distribution
US20250314577A1 (en) 2024-04-09 2025-10-09 Becton, Dickinson And Company Methods for assessing cell nuclei morphology and systems for same
US20250321179A1 (en) 2024-04-10 2025-10-16 Becton, Dickinson And Company Quantitative flow cytometry light scatter detector alignment
US20250341455A1 (en) 2024-05-03 2025-11-06 Becton, Dickinson And Company Flow cells having an optimized flow channel geometry, flow cytometers including the same, and methods of use thereof
US20250369861A1 (en) 2024-05-31 2025-12-04 Becton, Dickinson And Company Methods and systems for singlet discrimination in flow cytometry data and systems for same
US20250377284A1 (en) 2024-06-11 2025-12-11 Becton, Dickinson And Company Flow cells having optimized high voltage electrodes, flow cytometers including the same, and methods of use thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1350668A (zh) * 1999-05-26 2002-05-22 赛布尔仪器科技有限责任公司 带有实时流量测量和修正的宽范围气流系统
CN1606721A (zh) * 2001-10-12 2005-04-13 霍里巴斯特克公司 制造和使用质量流量设备的系统和方法
CN101321983A (zh) * 2005-12-07 2008-12-10 雅固拉器械公司 用于射流系统的脉动衰减器
US7776268B2 (en) * 2005-10-13 2010-08-17 Accuri Cytometers, Inc. User interface for a fluidic system of a flow cytometer

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60140139A (ja) * 1983-12-27 1985-07-25 Toa Medical Electronics Co Ltd 粒子計数装置
US5395588A (en) 1992-12-14 1995-03-07 Becton Dickinson And Company Control of flow cytometer having vacuum fluidics
US5915925A (en) 1997-01-07 1999-06-29 North, Jr.; Howard L. Pulseless liquid supply system for flow cytometry
JP3608066B2 (ja) * 1997-01-14 2005-01-05 株式会社日立製作所 粒子分析装置
IL124514A (en) * 1998-05-17 2002-02-10 Davidson Chaim Method and apparatus for magnetically separating selected particles, particularly biological cells
EP1018644A2 (en) * 1999-01-06 2000-07-12 Bayer Corporation Variable rate particle counter and method of use
GB2373054B (en) * 1999-05-26 2003-03-26 Cyber Instr Technology Llc Wide range gas flow system with real time flow measurement and correction
JP2001050887A (ja) * 1999-08-11 2001-02-23 Sysmex Corp 粒子分析装置
US7630063B2 (en) * 2000-08-02 2009-12-08 Honeywell International Inc. Miniaturized cytometer for detecting multiple species in a sample
US6382228B1 (en) * 2000-08-02 2002-05-07 Honeywell International Inc. Fluid driving system for flow cytometry
US20020028434A1 (en) * 2000-09-06 2002-03-07 Guava Technologies, Inc. Particle or cell analyzer and method
US20030211009A1 (en) * 2001-05-18 2003-11-13 Buchanan Kris S. Rapid multi-material sample input system
US7479630B2 (en) * 2004-03-25 2009-01-20 Bandura Dmitry R Method and apparatus for flow cytometry linked with elemental analysis
AU2002318269A1 (en) * 2001-07-18 2003-03-03 The Regents Of The University Of Michigan Gas-focusing flow cytometer cell and flow cytometer detection system with waveguide optics
EP1468266A4 (en) * 2002-01-22 2009-03-11 Beckman Coulter Inc ENVIRONMENTALLY COMPLETED SYSTEM FOR A FLOW CYTOMETER
US6694799B2 (en) * 2002-02-22 2004-02-24 Eastern Washington University Method and apparatus for detection of particles
US6825926B2 (en) * 2002-11-19 2004-11-30 International Remote Imaging Systems, Inc. Flow cell for urinalysis diagnostic system and method of making same
KR101166180B1 (ko) * 2003-08-13 2012-07-18 루미넥스 코포레이션 유세포 분석기식 측정 시스템의 하나 이상의 파라미터의 제어 방법
JP5138223B2 (ja) * 2003-10-30 2013-02-06 サイトノーム エスティー リミテッド ライアビリティー カンパニー 流体力学的多層シースフロー構造
EP1805500A4 (en) * 2004-09-28 2008-05-07 Singulex Inc SYSTEM AND METHOD FOR THE SPECTROSCOPIC ANALYSIS OF INDIVIDUAL PARTICLES
KR100670590B1 (ko) * 2005-10-05 2007-01-17 주식회사 디지탈바이오테크놀러지 확장된 채널을 가진 마이크로칩 및 이를 이용하는 미세입자 분석 장치
US8017402B2 (en) * 2006-03-08 2011-09-13 Accuri Cytometers, Inc. Fluidic system for a flow cytometer
US8303894B2 (en) * 2005-10-13 2012-11-06 Accuri Cytometers, Inc. Detection and fluidic system of a flow cytometer
US7780916B2 (en) * 2006-03-08 2010-08-24 Accuri Cytometers, Inc. Flow cytometer system with unclogging feature
US8283177B2 (en) * 2006-03-08 2012-10-09 Accuri Cytometers, Inc. Fluidic system with washing capabilities for a flow cytometer
US8715573B2 (en) * 2006-10-13 2014-05-06 Accuri Cytometers, Inc. Fluidic system for a flow cytometer with temporal processing
US8445286B2 (en) * 2006-11-07 2013-05-21 Accuri Cytometers, Inc. Flow cell for a flow cytometer system
US7799575B2 (en) * 2006-11-07 2010-09-21 Genetix Limited Flow cytometers
ES2945686T3 (es) * 2009-05-13 2023-07-05 Sartorius Bioanalytical Instr Inc Medición y control de flujo para cuantificación mejorada de partículas en citometría de flujo
US20110061471A1 (en) * 2009-06-02 2011-03-17 Rich Collin A System and method of verification of a sample for a flow cytometer
US8507279B2 (en) * 2009-06-02 2013-08-13 Accuri Cytometers, Inc. System and method of verification of a prepared sample for a flow cytometer
US8941062B2 (en) * 2010-11-16 2015-01-27 1087 Systems, Inc. System for identifying and sorting living cells

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1350668A (zh) * 1999-05-26 2002-05-22 赛布尔仪器科技有限责任公司 带有实时流量测量和修正的宽范围气流系统
CN1606721A (zh) * 2001-10-12 2005-04-13 霍里巴斯特克公司 制造和使用质量流量设备的系统和方法
US7776268B2 (en) * 2005-10-13 2010-08-17 Accuri Cytometers, Inc. User interface for a fluidic system of a flow cytometer
CN101321983A (zh) * 2005-12-07 2008-12-10 雅固拉器械公司 用于射流系统的脉动衰减器

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US20120103112A1 (en) 2012-05-03
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AU2011320713B2 (en) 2014-06-26
US20140158212A1 (en) 2014-06-12
US8528427B2 (en) 2013-09-10
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