ES2732355T3 - Sistema fluídico de vacío de retroalimentación dual para un analizador de partículas de tipo flujo - Google Patents

Sistema fluídico de vacío de retroalimentación dual para un analizador de partículas de tipo flujo Download PDF

Info

Publication number
ES2732355T3
ES2732355T3 ES11782698T ES11782698T ES2732355T3 ES 2732355 T3 ES2732355 T3 ES 2732355T3 ES 11782698 T ES11782698 T ES 11782698T ES 11782698 T ES11782698 T ES 11782698T ES 2732355 T3 ES2732355 T3 ES 2732355T3
Authority
ES
Spain
Prior art keywords
fluid
sample
flow
line
fluidic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES11782698T
Other languages
English (en)
Spanish (es)
Inventor
David Vrane
Pierce Norton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Application granted granted Critical
Publication of ES2732355T3 publication Critical patent/ES2732355T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G01N15/1409—Handling samples, e.g. injecting samples
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/0318—Processes
    • Y10T137/0324—With control of flow by a condition or characteristic of a fluid
    • Y10T137/0379—By fluid pressure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • Health & Medical Sciences (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Optical Measuring Cells (AREA)
  • Fluid Mechanics (AREA)
  • Engineering & Computer Science (AREA)
  • Automation & Control Theory (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
ES11782698T 2010-10-29 2011-10-24 Sistema fluídico de vacío de retroalimentación dual para un analizador de partículas de tipo flujo Active ES2732355T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40799010P 2010-10-29 2010-10-29
PCT/US2011/057445 WO2012058142A1 (en) 2010-10-29 2011-10-24 Dual feedback vacuum fluidics for a flow-type particle analyzer

Publications (1)

Publication Number Publication Date
ES2732355T3 true ES2732355T3 (es) 2019-11-22

Family

ID=44983697

Family Applications (1)

Application Number Title Priority Date Filing Date
ES11782698T Active ES2732355T3 (es) 2010-10-29 2011-10-24 Sistema fluídico de vacío de retroalimentación dual para un analizador de partículas de tipo flujo

Country Status (9)

Country Link
US (2) US8528427B2 (enExample)
EP (1) EP2633283B1 (enExample)
JP (1) JP5771696B2 (enExample)
CN (1) CN103201611B (enExample)
AU (1) AU2011320713B2 (enExample)
ES (1) ES2732355T3 (enExample)
SG (1) SG189532A1 (enExample)
WO (1) WO2012058142A1 (enExample)
ZA (1) ZA201302955B (enExample)

Families Citing this family (131)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG149889A1 (en) 2003-10-30 2009-02-27 Cytonome Inc Multilayer hydrodynamic sheath flow structure
EP2449359B1 (en) * 2009-07-02 2020-01-01 The Governors of the University of Alberta Particle classifier
SG183932A1 (en) * 2010-03-10 2012-10-30 Beckman Coulter Inc Generating pulse parameters in a particle analyzer
WO2014085585A1 (en) * 2012-11-29 2014-06-05 Cytoflow, Llc Fluidic system and method
EP4220124A1 (en) 2013-03-14 2023-08-02 Cytonome/ST, LLC Hydrodynamic focusing apparatus and methods
ES2711364T3 (es) * 2013-03-15 2019-05-03 Iris Int Inc Sistemas y métodos de célula de flujo para el análisis de partículas en muestras de sangre
US9372143B2 (en) * 2013-05-15 2016-06-21 Captl Llc Scanning image flow cytometer
US20150107711A1 (en) * 2013-10-21 2015-04-23 Cytoflow, Llc Cytometer flowcell
CN103837462B (zh) * 2014-03-03 2016-10-05 中国科学院苏州生物医学工程技术研究所 一种小型流式细胞仪液路系统
JP5873126B2 (ja) * 2014-04-04 2016-03-01 日本電信電話株式会社 送液方法および送液システム
WO2016089521A1 (en) 2014-12-04 2016-06-09 Becton, Dickinson And Company Flow cytometry cell sorting systems and methods of using the same
US9709769B2 (en) 2014-12-10 2017-07-18 Becton, Dickinson And Company Methods for optically aligning light collection components and optically aligned light collection systems thereof
US10900885B2 (en) 2014-12-19 2021-01-26 Captl Llc Flow cytometry using hydrodynamically planar flow
WO2016133760A1 (en) 2015-02-18 2016-08-25 Becton, Dickinson And Company Optical detection systems and methods of using the same
CN107923836B (zh) 2015-06-17 2020-12-01 贝克顿·迪金森公司 具有可移除散射杆的光学检测器散射帽组件及其使用方法
US10036698B2 (en) 2015-06-19 2018-07-31 Captl Llc Time-sequential cytometry
EP3362778B1 (en) 2015-10-13 2022-08-03 Omega Biosystems Incorporated Multi-modal fluorescence imaging flow cytometry system
WO2017156034A1 (en) 2016-03-10 2017-09-14 Becton, Dickinson And Company Methods of evaluating a cellular sample for her-2/neu expression and compositions for practicing the same
CA3018065A1 (en) 2016-03-17 2017-09-21 Bd Biosciences Cell sorting using a high throughput fluorescence flow cytometer
US11408812B2 (en) 2016-04-22 2022-08-09 Becton, Dickinson And Company High density deposition for array production
JP7023244B2 (ja) 2016-05-12 2022-02-21 ビーディー バイオサイエンス 画像解像度が改良された蛍光イメージングフローサイトメトリー
US10006852B2 (en) 2016-09-13 2018-06-26 Becton, Dickinson And Company Flow cytometer with optical equalization
SG11201808302VA (en) 2016-10-03 2018-10-30 Becton Dickinson Co Methods and systems for determining a drop delay of a flow stream in a flow cytometer
US10436697B2 (en) * 2016-11-19 2019-10-08 Cytek Biosciences, Inc. Flow cytometery system with fluidics control system
EP3541536B1 (en) * 2016-11-19 2025-10-22 Cytek Biosciences, Inc. Flow cytometry systems with stepper flow control valve
EP3555630B1 (en) 2016-12-14 2023-05-31 Becton, Dickinson and Company Methods and compositions for obtaining a tuberculosis assessment in a subject
JP7058662B2 (ja) 2017-02-08 2022-04-22 ベクトン・ディキンソン・アンド・カンパニー 乾燥色素試薬装置、ならびにその製造及び使用方法
JP7173978B2 (ja) 2017-02-27 2022-11-17 ベクトン・ディキンソン・アンド・カンパニー 光検出システム及びその使用方法
US10613020B2 (en) * 2017-08-10 2020-04-07 The Boeing Company Burr detection systems and methods
US10801617B2 (en) 2018-01-05 2020-10-13 Cnh Industrial America Llc Propel system with active pump displacement control for balancing propel pump pressures in agricultural vehicles
CN111758019B (zh) 2018-01-23 2024-06-28 贝克顿·迪金森公司 用于动态光检测遮蔽的系统及其使用方法
CN112384573A (zh) 2018-03-30 2021-02-19 贝克顿·迪金森公司 含侧基发色团的水溶性聚合染料
AU2019257598B2 (en) 2018-04-24 2025-01-02 Becton, Dickinson And Company Multi-laser systems having modified beam profiles and methods of use thereof
EP3785016A4 (en) 2018-04-26 2022-02-09 Becton, Dickinson and Company BIEXPONENTIAL TRANSFORMATION FOR PARTICLE SORTER
CN112154317B (zh) 2018-04-26 2024-11-08 贝克顿·迪金森公司 颗粒分析仪的表征和分选
EP3785017B1 (en) 2018-04-27 2025-09-10 Becton, Dickinson And Company Collection systems for flow cytometrically sorted samples and methods of using the same
CN112449680B (zh) 2018-06-19 2024-08-09 贝克顿·迪金森公司 用于检测器阵列、系统的可变多路复用开关及其使用方法
EP3814748B1 (en) 2018-06-28 2026-03-25 Becton, Dickinson and Company Integrated pre-amplification light detection systems and methods of use thereof
WO2020036730A1 (en) * 2018-08-15 2020-02-20 Becton, Dickinson And Company Flowrate and vacuum controlled fluid management system for a flow type particle analyzer
EP3844482B1 (en) 2018-08-30 2025-03-12 Becton, Dickinson and Company Characterization and sorting for particle analyzers
CN109357991B (zh) * 2018-09-27 2020-05-26 清华大学 一种免标记原理的质谱流式细胞进样与离子化装置
EP3874254B1 (en) 2018-10-30 2025-04-30 Becton, Dickinson and Company Particle sorting module with alignment window, systems and methods of use thereof
US11237093B2 (en) 2018-12-10 2022-02-01 Bio-Rad Laboratories, Inc. External fluidics system for flow cytometer
US11009400B2 (en) 2018-12-28 2021-05-18 Becton, Dickinson And Company Methods for spectrally resolving fluorophores of a sample and systems for same
US11085868B2 (en) 2019-02-08 2021-08-10 Becton, Dickinson And Company Droplet sorting decision modules, systems and methods of use thereof
EP4734073A2 (en) 2019-03-22 2026-04-29 Becton Dickinson and Company Spectral unmixing of fluorescence imaging using radiofrequency-multiplexed excitation data
EP3867627B1 (en) 2019-03-29 2023-10-25 Becton, Dickinson and Company Parameters for use in particle discrimination
JP7312135B2 (ja) * 2019-04-08 2023-07-20 アークレイ株式会社 送液方法及び分析装置
CN111796111B (zh) * 2019-04-08 2025-11-21 爱科来株式会社 送液方法和分析装置
JP7175231B2 (ja) * 2019-04-08 2022-11-18 アークレイ株式会社 検体の分析方法及び検体の分析装置
WO2020231632A1 (en) 2019-05-14 2020-11-19 Becton, Dickinson And Company Phase-calibration for imaging flow cytometry
US11579071B2 (en) 2019-05-30 2023-02-14 Becton, Dickinson And Company Phase-correction of radiofrequency-multiplexed signals
WO2021007075A1 (en) 2019-07-10 2021-01-14 Becton, Dickinson And Company Reconfigurable integrated circuits for adjusting cell sorting classification
WO2021055732A1 (en) * 2019-09-20 2021-03-25 Kansas State University Research Foundation Methods and apparatus for contactless orthographic imaging of aerosol particles
US11635375B2 (en) 2019-11-20 2023-04-25 Becton, Dickinson And Company Light detection module with adjustable sensitivity
WO2021127364A1 (en) 2019-12-20 2021-06-24 Becton, Dickinson And Company Methods for quantitating extra-cellular vesicle surface markers, and compositions for practicing the same
JP7663587B2 (ja) 2020-01-31 2025-04-16 ベクトン・ディキンソン・アンド・カンパニー 訓練ゲートを調整してフローサイトメータデータに適応させるための方法およびシステム
US11821830B2 (en) 2020-02-07 2023-11-21 Becton, Dickinson And Company Clustered wavelength division light detection systems and methods of using the same
JP7672419B2 (ja) 2020-02-19 2025-05-07 ベクトン・ディキンソン・アンド・カンパニー ストロボレーザ励起システム及びその使用方法
US11592386B2 (en) 2020-02-26 2023-02-28 Becton, Dickinson And Company Light detection systems having a secondary light scatter detector and methods for using same
EP4111169A4 (en) 2020-02-27 2023-08-09 Becton, Dickinson and Company METHODS FOR IDENTIFICATION OF SATURATED DATA SIGNALS IN CELL SORTING AND SYSTEMS THEREFOR
JP2023518457A (ja) 2020-03-17 2023-05-01 ベクトン・ディキンソン・アンド・カンパニー 光検出のための利得一致した増幅器
WO2021211259A1 (en) 2020-04-16 2021-10-21 Becton, Dickinson And Company Systems for light detection array multiplexing and methods for same
US11662297B2 (en) 2020-04-28 2023-05-30 Becton, Dickinson And Company Method for index sorting unique phenotypes and systems for same
CN115917293B (zh) 2020-04-29 2026-02-27 贝克顿·迪金森公司 在流式细胞仪中调节和同步检测的方法及系统
CN115917315A (zh) 2020-05-05 2023-04-04 贝克顿·迪金森公司 用于确定流式细胞仪中检测器增益的方法
WO2021225792A1 (en) 2020-05-06 2021-11-11 Becton, Dickinson And Company Methods and systems for characterizing spillover spreading in flow cytometer data
WO2021236339A1 (en) 2020-05-18 2021-11-25 Becton, Dickinson And Company Resolution indices for detecting heterogeneity in data and methods of use thereof
EP4168774A4 (en) 2020-06-19 2023-12-27 Becton, Dickinson and Company FLOW CYTOMETER WITH ADJUSTABLE POSITION OFFSET SORTING DEFLECTION PLATES AND METHOD OF USE THEREOF
EP4171819B1 (en) 2020-06-24 2026-07-22 Becton, Dickinson and Company Flow cytometric droplet dispensing systems and methods for using the same
WO2021262285A1 (en) 2020-06-26 2021-12-30 Becton, Dickinson And Company Dual excitation beams for irradiating a sample in a flow stream and methods for using same
US11965813B2 (en) 2020-08-03 2024-04-23 Cytek Biosciences, Inc. Methods and apparatus for central source pressure-based cytometer fluidics system
WO2022066316A1 (en) 2020-09-22 2022-03-31 Becton, Dickinson And Company Methods for continuous measurement of baseline noise in a flow cytometer and systems for same
US20220120658A1 (en) 2020-10-20 2022-04-21 Becton, Dickinson And Company Flow cytometers including tilted beam shaping optical components, and methods of using the same
WO2022093931A1 (en) 2020-10-30 2022-05-05 Becton, Dickinson And Company Method and systems for characterizing and encoding a light detection system
WO2022103574A1 (en) 2020-11-16 2022-05-19 Becton, Dickinson And Company Flow cyometers including light collection modules, and methods of using the same
US12306087B2 (en) 2020-11-19 2025-05-20 Becton, Dickinson And Company Method for optimal scaling of cytometry data for machine learning analysis and systems for same
WO2022155033A1 (en) 2021-01-13 2022-07-21 Becton, Dickinson And Company Flow cytometers including light collection enhancers, and methods of using the same
CN112903569A (zh) 2021-01-20 2021-06-04 贝克曼库尔特生物科技（苏州）有限公司 用于计算液滴延迟时间的系统和方法以及分选装置
CN214844688U (zh) 2021-01-22 2021-11-23 贝克曼库尔特生物科技（苏州）有限公司 用于样本处理仪的透明管组件和流式池及样本处理仪
WO2022159190A1 (en) 2021-01-25 2022-07-28 Becton, Dickinson And Company Method and systems for determing drop delay using scatter signals across spatially separated lasers
CN214895849U (zh) 2021-01-28 2021-11-26 贝克曼库尔特生物科技（苏州）有限公司 气泡检测装置和样本处理仪
CN117098980A (zh) 2021-02-04 2023-11-21 贝克顿·迪金森公司 集成光询问模块及其使用方法
US12285761B2 (en) 2021-02-05 2025-04-29 Cytek Biosciences, Inc. Integrated air filtering and conditioning of droplet chamber in a compact cell sorter
EP4314765A4 (en) 2021-03-24 2024-10-16 Becton, Dickinson and Company Closed-system sorting flow cytometer adapters and methods of use thereof
WO2022225597A1 (en) * 2021-04-23 2022-10-27 Becton, Dickinson And Company Fluid management system for an analyzer and/or sorter type flow type particle analyzer
WO2022240552A1 (en) 2021-05-14 2022-11-17 Becton, Dickinson And Company Systems for detecting light by spectral discrimination and methods for using same
EP4381277A4 (en) 2021-08-04 2024-12-04 Becton, Dickinson and Company Light detection systems having first and second light receivers, and methods of use thereof
US12467845B2 (en) 2021-08-10 2025-11-11 Becton, Dickinson And Company Clamps for operably coupling an optical component to a mounting block, and methods and systems for using the same
US12135274B2 (en) 2021-08-10 2024-11-05 Becton, Dickinson And Company Outlet fittings for reducing bubbles at the interface with a flow cell, and flow cytometers and methods using the same
WO2023048903A1 (en) 2021-09-21 2023-03-30 Becton, Dickinson And Company Baseline restoration circuit
CA3230701A1 (en) 2021-11-17 2023-05-25 Keegan Owsley Methods for dynamic real-time adjustment of a data acquisition parameter in a flow cytometer
EP4437324A4 (en) 2021-11-24 2025-03-05 Becton, Dickinson and Company Integrated flow cytometry data quality control
CN114594040B (zh) * 2022-03-23 2025-01-03 青岛瑞斯凯尔生物科技股份有限公司 一种流式细胞仪及其工作方法
CN117054177A (zh) * 2022-05-07 2023-11-14 贝克曼库尔特生物科技（苏州）有限公司 流体系统、样本处理仪和在样本处理仪中输送流体的方法
US12287274B2 (en) 2022-06-06 2025-04-29 Becton, Dickinson And Company Fluidic resistance units, as well as flow cytometers and methods involving the same
CN120813702A (zh) 2023-02-28 2025-10-17 贝克顿·迪金森公司 用于获取关联的单细胞细胞计数数据与测序数据的双索引颗粒标记
US20240312191A1 (en) 2023-03-14 2024-09-19 Becton, Dickinson And Company Methods for determining image filters for classifying particles of a sample and systems and methods for using same
US20240344983A1 (en) 2023-03-30 2024-10-17 Becton, Dickinson And Company Methods and systems for visualizing spectral signatures
JP2026518518A (ja) 2023-04-13 2026-06-09 ベクトン・ディキンソン・アンド・カンパニー 分子診断信号をリアルタイムで分類する方法
EP4454548A1 (en) * 2023-04-25 2024-10-30 Koninklijke Philips N.V. Air flow control for hemodynamic measurement cuff
US20240377311A1 (en) 2023-05-09 2024-11-14 Becton, Dickinson And Company Methods for image-based detection and sorting and systems for same
US20240377307A1 (en) 2023-05-09 2024-11-14 Becton, Dickinson And Company Methods and systems for classifying analyte data into clusters
US20240377325A1 (en) 2023-05-09 2024-11-14 Becton, Dickinson And Company Methods for assessing cell mitochondrial morphology and systems for same
US20250085212A1 (en) 2023-09-07 2025-03-13 Becton, Dickinson And Company Integrated Optofluidic Interrogation Modules, Flow Cytometers Including the Same, and Methods of Use Thereof
US20250137905A1 (en) 2023-10-27 2025-05-01 Becton, Dickinson And Company Fluid Supply Systems Having a Flow Control Circuit and Single Fluidic Connection, and Methods of Use Thereof
US20250237657A1 (en) 2024-01-18 2025-07-24 Becton, Dickinson And Company Methods for spectrally resolving fluorophores of a sample by generalized least squares and systems for same
US20250244333A1 (en) 2024-01-31 2025-07-31 Becton, Dickinson And Company Cell viability compensation (cvc) beads for flow cytometry applications and methods of using the same
US20250297940A1 (en) 2024-03-25 2025-09-25 Becton, Dickinson And Company Methods and systems for classifying analyte data
US20250308080A1 (en) 2024-04-02 2025-10-02 Becton, Dickinson And Company Methods for label-free cell sorting and systems for same
US20250314573A1 (en) 2024-04-05 2025-10-09 Becton, Dickinson And Company Gate/population naming in flow cytometry data analysis based on geometry and data distribution
US20250314577A1 (en) 2024-04-09 2025-10-09 Becton, Dickinson And Company Methods for assessing cell nuclei morphology and systems for same
US20250321179A1 (en) 2024-04-10 2025-10-16 Becton, Dickinson And Company Quantitative flow cytometry light scatter detector alignment
US20250341455A1 (en) 2024-05-03 2025-11-06 Becton, Dickinson And Company Flow cells having an optimized flow channel geometry, flow cytometers including the same, and methods of use thereof
US20250369861A1 (en) 2024-05-31 2025-12-04 Becton, Dickinson And Company Methods and systems for singlet discrimination in flow cytometry data and systems for same
US20250377284A1 (en) 2024-06-11 2025-12-11 Becton, Dickinson And Company Flow cells having optimized high voltage electrodes, flow cytometers including the same, and methods of use thereof
US20250382585A1 (en) 2024-06-13 2025-12-18 Nippon Becton Dickinson Company Ltd Tumor and tissue preservation reagent
US20250389636A1 (en) 2024-06-24 2025-12-25 Becton, Dickinson And Company Methods and systems for gain-independent data normalization in flow cytometry data and systems for same
US20260002864A1 (en) 2024-06-28 2026-01-01 Becton, Dickinson And Company Methods for determining positional flow stream velocity and systems for same
US20260009715A1 (en) 2024-07-03 2026-01-08 Becton, Dickinson And Company Method for flow cytometry quality scores and systems for same
EP4703707A1 (en) 2024-08-27 2026-03-04 Becton Dickinson and Company Methods and compositions for flow cytometer calibration
US20260086018A1 (en) 2024-09-26 2026-03-26 Becton, Dickinson And Company Methods for detector gain modulation and systems for same
US20260140039A1 (en) 2024-10-09 2026-05-21 Becton, Dickinson And Company Methods for monitoring flow rate of a flow stream and systems for same
US20260118250A1 (en) 2024-10-25 2026-04-30 Becton, Dickinson And Company Methods for assessing collinearity of multi-autofluorescence spectra of a sample and systems for same
US20260126373A1 (en) 2024-11-06 2026-05-07 Becton, Dickinson And Company Flow cytometer sample injection needle
US20260133114A1 (en) 2024-11-08 2026-05-14 Becton, Dickinson And Company Flow cytometer having a pneumatically driven sample autoloader, and methods of using the same
US20260133113A1 (en) 2024-11-08 2026-05-14 Becton, Dickinson And Company Flow cytometer having a variable depth sample line injection tube, and methods of using the same
US20260133213A1 (en) 2024-11-12 2026-05-14 Becton, Dickinson And Company Automated flow cytometry preparation and acquisition system, and methods of use thereof
US20260133126A1 (en) 2024-11-14 2026-05-14 Becton, Dickinson And Company Methods for assessing a fluorochrome panel for use in analysis of flow cytometry data and systems for same
US20260212503A1 (en) 2025-01-23 2026-07-23 Becton, Dickinson And Company Methods for high precision cancer cell discrimination and systems for same
US20260227322A1 (en) 2025-01-31 2026-08-06 Becton, Dickinson And Company Methods for calibrating spectral data signals in flow cytometry data and systems for same

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60140139A (ja) * 1983-12-27 1985-07-25 Toa Medical Electronics Co Ltd 粒子計数装置
US5395588A (en) 1992-12-14 1995-03-07 Becton Dickinson And Company Control of flow cytometer having vacuum fluidics
US5915925A (en) 1997-01-07 1999-06-29 North, Jr.; Howard L. Pulseless liquid supply system for flow cytometry
JP3608066B2 (ja) * 1997-01-14 2005-01-05 株式会社日立製作所 粒子分析装置
IL124514A (en) * 1998-05-17 2002-02-10 Davidson Chaim Method and apparatus for magnetically separating selected particles, particularly biological cells
JP2000206032A (ja) * 1999-01-06 2000-07-28 Bayer Corp 可変割合体積粒子計数装置及び試料の特性を定める方法
GB2373054B (en) * 1999-05-26 2003-03-26 Cyber Instr Technology Llc Wide range gas flow system with real time flow measurement and correction
US6119710A (en) * 1999-05-26 2000-09-19 Cyber Instrument Technologies Llc Method for wide range gas flow system with real time flow measurement and correction
JP2001050887A (ja) * 1999-08-11 2001-02-23 Sysmex Corp 粒子分析装置
US7630063B2 (en) * 2000-08-02 2009-12-08 Honeywell International Inc. Miniaturized cytometer for detecting multiple species in a sample
US6382228B1 (en) * 2000-08-02 2002-05-07 Honeywell International Inc. Fluid driving system for flow cytometry
US20020028434A1 (en) * 2000-09-06 2002-03-07 Guava Technologies, Inc. Particle or cell analyzer and method
US20030211009A1 (en) * 2001-05-18 2003-11-13 Buchanan Kris S. Rapid multi-material sample input system
US7479630B2 (en) * 2004-03-25 2009-01-20 Bandura Dmitry R Method and apparatus for flow cytometry linked with elemental analysis
WO2003008937A2 (en) * 2001-07-18 2003-01-30 The Regents Of The University Of Michigan Gas-focusing flow cytometer cell and flow cytometer detection system with waveguide optics
EP1442343B1 (en) * 2001-10-12 2008-05-14 Horiba Stec, Inc. System and method for making and using a mass flow device
EP1468266A4 (en) * 2002-01-22 2009-03-11 Beckman Coulter Inc ENVIRONMENTALLY COMPLETED SYSTEM FOR A FLOW CYTOMETER
US6694799B2 (en) * 2002-02-22 2004-02-24 Eastern Washington University Method and apparatus for detection of particles
US6825926B2 (en) * 2002-11-19 2004-11-30 International Remote Imaging Systems, Inc. Flow cell for urinalysis diagnostic system and method of making same
KR101166180B1 (ko) * 2003-08-13 2012-07-18 루미넥스 코포레이션 유세포 분석기식 측정 시스템의 하나 이상의 파라미터의 제어 방법
SG149889A1 (en) * 2003-10-30 2009-02-27 Cytonome Inc Multilayer hydrodynamic sheath flow structure
EP1805500A4 (en) * 2004-09-28 2008-05-07 Singulex Inc SYSTEM AND METHOD FOR THE SPECTROSCOPIC ANALYSIS OF INDIVIDUAL PARTICLES
KR100670590B1 (ko) * 2005-10-05 2007-01-17 주식회사 디지탈바이오테크놀러지 확장된 채널을 가진 마이크로칩 및 이를 이용하는 미세입자 분석 장치
US7776268B2 (en) 2005-10-13 2010-08-17 Accuri Cytometers, Inc. User interface for a fluidic system of a flow cytometer
US8303894B2 (en) * 2005-10-13 2012-11-06 Accuri Cytometers, Inc. Detection and fluidic system of a flow cytometer
US8017402B2 (en) * 2006-03-08 2011-09-13 Accuri Cytometers, Inc. Fluidic system for a flow cytometer
US7328722B2 (en) * 2005-12-07 2008-02-12 Accuri Cytometers, Inc. Pulsation attenuator for a fluidic system
US7780916B2 (en) * 2006-03-08 2010-08-24 Accuri Cytometers, Inc. Flow cytometer system with unclogging feature
US8283177B2 (en) * 2006-03-08 2012-10-09 Accuri Cytometers, Inc. Fluidic system with washing capabilities for a flow cytometer
US8715573B2 (en) * 2006-10-13 2014-05-06 Accuri Cytometers, Inc. Fluidic system for a flow cytometer with temporal processing
US7799575B2 (en) * 2006-11-07 2010-09-21 Genetix Limited Flow cytometers
WO2008058217A2 (en) * 2006-11-07 2008-05-15 Accuri Instruments Inc. Flow cell for a flow cytometer system
WO2010132053A1 (en) * 2009-05-13 2010-11-18 Indevr, Inc. Flow measurement and control for improved quantification of particles in flow cytometry
US8507279B2 (en) * 2009-06-02 2013-08-13 Accuri Cytometers, Inc. System and method of verification of a prepared sample for a flow cytometer
US20110061471A1 (en) * 2009-06-02 2011-03-17 Rich Collin A System and method of verification of a sample for a flow cytometer
US8941062B2 (en) * 2010-11-16 2015-01-27 1087 Systems, Inc. System for identifying and sorting living cells

Also Published As

Publication number Publication date
CN103201611B (zh) 2015-03-11
CN103201611A (zh) 2013-07-10
US20120103112A1 (en) 2012-05-03
SG189532A1 (en) 2013-05-31
EP2633283B1 (en) 2019-05-01
JP5771696B2 (ja) 2015-09-02
EP2633283A1 (en) 2013-09-04
US9092034B2 (en) 2015-07-28
US20140158212A1 (en) 2014-06-12
AU2011320713B2 (en) 2014-06-26
JP2014503792A (ja) 2014-02-13
US8528427B2 (en) 2013-09-10
ZA201302955B (en) 2014-10-29
WO2012058142A1 (en) 2012-05-03

Similar Documents

Publication Publication Date Title
US8528427B2 (en) Dual feedback vacuum fluidics for a flow-type particle analyzer
US20120125126A1 (en) Fluidics with thermal compensation for a flow-type particle analyzer
US6110427A (en) Flow regulator to maintain controllable volumetric flow rate
US9170187B2 (en) Flow cytometer and fluidic system thereof
US5040890A (en) Sheathed particle flow controlled by differential pressure
US7760351B2 (en) Cytometer having fluid core stream position control
US10221844B2 (en) Fluid handling system for a particle processing apparatus
ES2881690T3 (es) Aparato y método para determinar la tasa de sedimentación de la sangre y otros parámetros relacionados con la misma
JP2018513373A (ja) 粒子計数装置
JP7072475B2 (ja) 粒子分析装置
US7319524B2 (en) Air purged optical densitometer
CN110118716A (zh) 流式细胞仪的液流系统、气密性检测方法与流式细胞仪
JP4540506B2 (ja) 試料液流の位置制御方法および装置
CN103298397B (zh) 管路内流量计
US4226532A (en) Device for granulometric analysis of particles in fluids
US3418061A (en) Flow cell construction with delivery and discharge means
RU2348920C1 (ru) Фотоэлектрическое устройство для определения размера и концентрации частиц в потоке жидкости
USH1027H (en) Aerosol modulating nozzle
JPH0714372U (ja) フローセル形検出器
JPH02259449A (ja) サンプル検査装置
ES2895504T3 (es) Dispositivo hidrofoco con una única disolución de análisis
JPS5973724A (ja) 液滴検出装置
CN119452240A (zh) 流体阻滞单元以及涉及其的流式细胞仪和方法
CN110260935A (zh) 一种流量检测装置