CN103191319B - Medicine for treating epistaxis and preparation method thereof - Google Patents

Abstract

The invention discloses a medicine for treating epistaxis and a preparation method thereof. The medicine is prepared from cape jasmine, radix ophiopogonis, lalang grass rhizome, herba portulacae, roots of madder, liquorice, donkey-hide gelatin and the like according to a certain weight ratio. The medicine disclosed by the invention has the functions of warming channel and promoting lactation, clearing away heat and reducing fire, and cooling blood and stopping blooding, is good in curative effect and high in recovery rate in treatment of epistaxis, and fast becomes effective.

Description

A kind of medicine for the treatment of epistaxis and preparation method thereof

Technical field

The present invention relates to a kind of medicine for the treatment of epistaxis and preparation method thereof, belong to the field of Chinese medicines.

Background technology

Blood, from cleaning the street for nose, is called epistaxis.It is common a kind of disease.Partially contain mainly due to lung, stomach, liver-fire heat, the absurd row of forcing blood, so that blood oozing from the body openings or subcuta neous tissue cleans the street, and flows out and forms epistaxis from nostril, also has minority by person due to deficiency of kidney-essence or deficient QI failing to control.Epistaxis is also called nosebleed.When epistaxis amount is many, be called again serious epistaxis or profuse nose-bleed.Namely commonly go out nose bleeding.Epistaxis also claims epistaxis rather common, generally can be divided into two classes, by the epistaxis due to nose local cause with as the symptomatic epistaxis of the topical manifestations of systemic disease.Especially more common with symptomatic epistaxis, its sickness rate is about the former 2 times.The epistaxis that local factor causes is mostly one-sided property, and hemorrhage mostly occurring is imbued with the position of blood capillary prerolandic artery Rolando in nasal septum front portion.Herein tissue elasticity lower, while being stimulated (as digging nose, dry, dust etc.), mucosa blood vessel easily breaks, and causes hemorrhage.Symptomatic epistaxis is found in blood vessel and kidney disease (as blood vessel wall infringement, uremia etc.).Hemorrhagic diathesis and some infectious disease (as influenza, measles, diphtheria, typhoid fever etc.).Hereditary hemorrhagic peripheral vessel di patient's the congenital weakness of blood vessel wall, slightly expansion can be broken hemorrhage.Western medicine cannot effectively be treated epistaxis at present, and has certain side effect, and therefore, people exist great demand to the Chinese medicine of effective treatment epistaxis.

Summary of the invention

The inventor, according to the research of theory of Chinese medical science and clinical test and checking repeatedly, has finally found the medicine of effective treatment epistaxis, thereby has completed the present invention.

Object of the present invention is just to provide a kind of composition of medicine that can treat epistaxis.

Another object of the present invention has just been to provide the preparation method of this composition of medicine.

Medicine of the present invention selects Fructus Gardeniae, Herba Agrimoniae, Radix Ophiopogonis, Nodus Nelumbinis Rhizomatis, Rhizoma Imperatae, Herba Portulacae, Radix Angelicae Sinensis, Radix Rubiae, Ramulus Cinnamomi, Folium Artemisiae Argyi, Flos Chrysanthemi, Radix Rehmanniae, Concha Ostreae, Rhizoma Dioscoreae, Radix Paeoniae Rubra, Mirabilitum crystallina, Haematitum, Radix Glycyrrhizae, Colla Corii Asini, Radix Scutellariae, Arillus Longan, Mel medicine to combine, make each efficacy of drugs produce synergism these drug regimens, thus recurrence that can fast treating epistaxis.Wherein select Fructus Gardeniae to be because its nature and flavor hardship is cold, enter the heart, liver, lung, stomach warp, have heat clearing away, pathogenic fire purging, the function of removing heat from blood, controls calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quenches one's thirst, conjunctival congestion, pharyngalgia, spits blood, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprains and swells and ache.Select Herba Agrimoniae to be because its nature and flavor toil is flat, enter lung, liver, spleen channel, have hemostasis, the function of stomach invigorating, controls spitting of blood, spits blood, and hematuria, has blood in stool, dysentery, and bleeding not during menses, impairment caused by overstrain takes off power, carbuncle, traumatic injury, wound hemorrhage.Select be Radix Ophiopogonis because its property sweet and slightly bitter taste is cold, enter lung, stomach, heart channel, have nourishing YIN and moistening the lung, the relieving restlessness that clears away heart-fire, the function of reinforcing stomach reg fluid, controls dryness of the lung dry cough, spits blood, spitting of blood, consumptive lung disease, lung abscess, asthenia dysphoria with smothery sensation, thirsty clearly, calentura Tianjin wound, dry mouth and throat, constipation.Select Nodus Nelumbinis Rhizomatis to be because its property sweet-puckery flavor is flat, few the moon of starting with, foot sun is bright, and JUE YIN meridian, has hemostasis, and the function of dissipating blood stasis, controls hemoptysis, spits blood, epistaxis, hematuria, has blood in stool, dysentery, metrorrhagia.It is sweet because of its nature and flavor, cold selecting Rhizoma Imperatae, enters lung, stomach, small intestine meridian, has removing heat from blood, hemostasis, and heat clearing away, the function of diuresis, controls calentura excessive thirst, spits blood, epistaxis, lung-heat dyspnea with rapid respiration, gastric heat hiccup, gonorrhea, dysuria, edema, jaundice.Select Herba Portulacae to be because its nature and flavor acid is cold, enter large intestine, liver, spleen channel, have heat-clearing and toxic substances removing, the function of loose blood detumescence, controls hematodiarrhoea pus and blood, pyretic stranguria, stranguria with blood, leukorrhagia, carbuncle malignant boil, erysipelas, scrofula.Select Radix Angelicae Sinensis to be because its nature and flavor sweet, acrid, warm enters the heart, liver, spleen channel, have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, the function of moisturizing laxation, control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty just, heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Select Radix Rubiae to be because its nature and flavor hardship is cold, enter the heart, Liver Channel, have promoting the circulation of blood hemostasis, dredge the meridian passage, eliminating phlegm and stopping cough, controls haematemesis, epistaxis, hematuria, has blood in stool, metrorrhagia, amenorrhea, rheumatic arthralgia, traumatic injury, the stasis of blood is stagnant to swell and ache, jaundice, property tracheitis.Selecting Ramulus Cinnamomi is that temperature, enters bladder, the heart, lung meridian, has diaphoresis expelling pathogenic factors from muscles because of its property acrid-sweet flavor, and the function of warming the meridian and promoting blood circulation, controls exterior syndrome due to wind-cold, shoulder back of the body podomere ache, thoracic obstruction phlegm retention, amenorrhea and mass in the abdomen.Folium Artemisiae Argyi is because of its nature and flavor toil, temperature.Enter spleen, liver, kidney channel.The blood of regulating the flow of vital energy, by cold-damp; Warming the meridian, hemostasis, antiabortive.Control trusted subordinate's cold type of pain, the convulsion of having loose bowels, chronic dysentery, tells nosebleed, hematochezia, menoxenia, metrorrhagia, leukorrhagia, frequent fetal movement, carbuncle and ulcer, scabies.Select Flos Chrysanthemi to be because its nature and flavor sweetness and bitterness is cool, enter lung, Liver Channel, has dispelling wind, the heat that disappears, and improving eyesight, the function of removing toxic substances, controls headache, dizzy, conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, toxic swelling.Select Radix Rehmanniae to be because its nature and flavor are sweet, cold, GUIXIN, liver, kidney channel, have clearing away heat and cooling blood, yin nourishing, and the function of promoting the production of body fluid, controls calentura excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis, sends out speckle dermexanthesis.Select Concha Ostreae to be because its nature and flavor are salty and bitter, cool, enter liver, kidney channel, have yin fluid astringing, YANG hyperactivity suppressing, hidroschesis, arresting seminal emission, reduces phlegm, the function of softening the hard mass, Zhi Jing Epilepsy, dizzy, spontaneous perspiration, night sweat, seminal emission, stranguria with turbid discharge, metrorrhagia, leukorrhagia, scrofula, goiter.Select Rhizoma Dioscoreae to be because its nature and flavor are sweet, flat, enter lung, spleen, kidney channel, there is spleen invigorating, tonifying the lung, reinforces the kidney, and the function of benefit essence, controls diarrhea due to hypofunction of the spleen, chronic dysentery, cough due to consumptive disease, quenches one's thirst, seminal emission, leukorrhagia, frequent micturition.Select Radix Paeoniae Rubra to be because its nature and flavor hardship is slightly cold, return Liver Channel, have clearing away heat and cooling blood, the function of eliminating stasis to stop pain, controls warm poison and goes mad, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea ， Epilepsy abdominal mass stomachache, injury from falling down, carbuncle skin infection.Select Mirabilitum crystallina to be because its nature and flavor are pungent salty, cold, enter the heart, stomach, kidney channel, there is resolving heat and reducing pathogenic fire, sharp key, the function of detumescence, row calentura while controlling, accumulated heat excessive thirst, vomits and diarrhoea, edema, urine retention, bleeding from the gum, erysipelas, scalds.Select Haematitum to be because its nature and flavor hardship, sweet is slightly cold, return liver, stomach, heart channel, have suppressing the hyperactive liver and subsiding YANG, important city sending down the abnormal ascending QI, the function of cooling blood for hemostasis, controls head front dizzy, and cardiopalmus is demented, infantile convulsion, vomiting, eructation, cough and asthma, spits blood, epistaxis, metrorrhagia, has blood in stool, hematuria.Select Radix Glycyrrhizae to be because its nature and flavor are sweet flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach lack of appetite, stomachache loose stool, overstrain heating, consumptive lung disease cough, cardiopalmus, frightened carbuncle, raw with controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores, separates poison of drug and alimentary toxicosis.Select Colla Corii Asini to be because its nature and flavor are sweet flat, enter lung, liver, kidney channel, have nourishing YIN and supplementing blood, antiabortive function, controls blood deficiency, and cough due to consumptive disease, is had blood in stool at haematemesis, epistaxis, menoxenia, and metrorrhagia, controls leakage.Select Radix Scutellariae to be because its nature and flavor bitter cold enters cardiopulmonary, gallbladder, large intestine channel, have removing the relative excess fire, except damp and hot, the function of arresting bleeding and miscarriage prevention, controls high fever excessive thirst, cough due to lung-heat.Select Arillus Longan to be because its nature and flavor are sweet, temperature, enters the heart, spleen channel, has heart-spleen boosting, fills blood, and the function of calming the nerves, controls virtual work thin and weak, and insomnia is forgetful, palpitation with fear, severe palpitation.Select Mel to be because its nature and flavor are sweet, flat, enter lung, spleen, large intestine channel, there is invigorating middle warmer, moisturize, pain relieving, the function of removing toxic substances, controls xeropulmonary cough, dryness of the intestine constipation, gastralgia, nasal sinusitis, aphtha, the burning hot wound of soup, separates Aconitum Carmichaeli.

The specific embodiment

The drug dose of component of the present invention is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight

Fructus Gardeniae 2-10 gram Herba Agrimoniae 10-20 gram Radix Ophiopogonis 5-15 gram

Nodus Nelumbinis Rhizomatis 5-10 gram of Rhizoma Imperatae 10-20 Rana nigromaculata bitterroot 10-15 gram

Radix Angelicae Sinensis 5-15 gram of Radix Rubiae 5-15 gram of Ramulus Cinnamomi 2-8 gram

Folium Artemisiae Argyi 4-9 gram of Flos Chrysanthemi 5-10 gram of Radix Rehmanniae 5-15 gram

5-15 gram of Radix Paeoniae Rubra 3-7 gram of Concha Ostreae 5-15 Keshan medicine

Mirabilitum crystallina 10-20 gram of Haematitum 10-15 gram of Radix Glycyrrhizae 5-15 gram

Colla Corii Asini 3-7 gram of Radix Scutellariae 5-15 gram of Arillus Longan 5-15 gram

Mel 10-15 gram

Wherein, be preferably

10 grams of 6 grams of Herba Agrimoniaes of Fructus Gardeniae 15 grams of Radix Ophiopogonis

12 grams of 8 grams of Rhizoma Imperataes of Nodus Nelumbinis Rhizomatis, 15 Rana nigromaculata bitterroots

5 grams of 10 grams of Ramulus Cinnamomi of 10 grams of Radix Rubiae of Radix Angelicae Sinensis

10 grams of 8 grams of Radix Rehmanniae of 7 grams of Flos Chrysanthemis of Folium Artemisiae Argyi

5 grams of 10 grams of Radix Paeoniae Rubra of Concha Ostreae 10 Keshan medicine

10 grams, 12 grams of Radix Glycyrrhizaes of 15 grams of Haematitums of Mirabilitum crystallina

10 grams of 10 grams of Arillus Longans of 5 grams of Radix Scutellariaes of Colla Corii Asini

12 grams of Mel

The preparation method of medicine of the present invention is as follows

One, get the raw materials ready

1, Fructus Gardeniae: get the Fructus Gardeniae of pulverizing, put in pot and fry with high heat to pitchy, take out, cool;

2, Herba Agrimoniae: remove impurity undesirable root, clean, run through, cut off, dry;

3, Radix Ophiopogonis: choose clean impurity, be soaked in water, pull out, pump the heart after running through, then clean and dry;

4, Nodus Nelumbinis Rhizomatis: get clean Nodus Nelumbinis Rhizomatis and put in pot and fry and be black to outside, inside is strong yellow, slightly spills clear water, takes out, dry;

5, Rhizoma Imperatae: choose clean impurity, clean, micro-profit, cutting, dries, the clean chip of winnowing with a dustpan;

6, Herba Portulacae: choose clean impurity, remove undesirable root, slightly moisten with water, cutting is dried;

7, Radix Angelicae Sinensis: choose decontamination, clean, moistening, slightly dries in the air when suitable to inside and outside humidity, and section is dried;

8, Radix Rubiae: choose clean impurity, remove Lu Miao, clean, run through rear timely section, dry;

9, Ramulus Cinnamomi: water slightly soaks, pulls out, and moistening, to thoroughly, is cut into slices, and dries, and sieves anti-dandruff;

10, Folium Artemisiae Argyi: choose decontamination, destemming, sieve dedust bits;

11, Flos Chrysanthemi: choose clean leaf stalk, anthocaulus and spare impurity;

12, Radix Rehmanniae: get clean Radix Rehmanniae pornographic movie, put in pot with high heat or moderate heat heating, constantly stir-fry, fry and be coke black to surface, inner coke yellow or burnt brown;

13, Concha Ostreae: clean, dry, pulverize use;

14, Rhizoma Dioscoreae: choose clean impurity, be soaked in water to Rhizoma Dioscoreae central part soften for degree, pull out slightly and dry in the air, section dry or dry;

15, Radix Paeoniae Rubra: get crude drug, remove impurity, big or small stepping, cleans, runs through, shave, and dry, sieve removes chip;

16, Mirabilitum crystallina: get crude drug, remove impurity, cleaning, drying, break into fragment;

17, Haematitum: get crude drug, remove impurity, cleaning, drying, break into fragment or be ground into coarse powder;

18, Radix Glycyrrhizae: choose decontamination, clean, be soaked in water and, pull out thoroughly time to eighty per cant, run through section, airing;

19, Colla Corii Asini: smash use to pieces;

20, Radix Scutellariae: choose decontamination, remove residual stem, with cold water infiltrate or put in boiled water and slightly soak and pull out, section, dry;

21, Arillus Longan: get crude drug, remove impurity;

22, Mel: get pure Mel, temper with slow fire, filter skimming.

Two, preparation

The Fructus Gardeniae of described weight, Herba Agrimoniae, Radix Ophiopogonis, Nodus Nelumbinis Rhizomatis, Rhizoma Imperatae, Herba Portulacae, Radix Angelicae Sinensis, Radix Rubiae, Ramulus Cinnamomi, Folium Artemisiae Argyi, Flos Chrysanthemi, Radix Rehmanniae, Concha Ostreae, Rhizoma Dioscoreae, Radix Paeoniae Rubra, Mirabilitum crystallina, Haematitum, Radix Glycyrrhizae, Colla Corii Asini, Radix Scutellariae, Arillus Longan, Mel medicine are added to 6 times of water gagings to be soaked 60 minutes, intense fire decocts boiling 20 minutes, add again 3 times of water gagings and use again slow fire boiling 30 minutes, must take medicinal liquid, will take medicinal liquid and be equally divided into 4 doses.

Medicine of the present invention has the function of warming the meridian and promoting blood circulation, clearing away heat-fire, cooling blood for hemostasis.Treatment epistaxis instant effect, short treating period, do not recur, and cure rate is high.

Further set forth below the beneficial effect of medicine of the present invention by test example, these tests comprise animal toxicity test and the clinical observation test of medicine of the present invention.

The animal toxicity test report of [test example 1] medicine of the present invention

Get 20 of rabbit, male and female dual-purpose, body weight 2.0-2.5kg, divides two groups, and 10 every group, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 30ml/kg, and normal amount is 15ml/kg, and administering mode is administration by gavage administration, every day 2 times, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit activities, diet are normal, and medicine is without bad toxic and side effects.

The clinical observation material of [test example 2] medicine of the present invention

1, physical data

Accept out-patient's 200 examples for medical treatment.

2, diagnostic criteria

(1) blood flows out from nostril, can be diagnosed as epistaxis.Epistaxis the lighter, is only with the blood streak in tears; Severe patient, blood is gushed out from mouth and nose.

(2) very person of epistaxis, blood can overflow to go out from mouth, or because a large amount of blood is ingested, vomiting in a moment.Therefore, epistaxis should be differentiated mutually with haematemesis, spitting of blood.Spitting of blood is the injured caused disease of lung network, and its blood must go out through air flue cough, mixture of phlegm and blood, or sputum mixed with blood silk, or pure blood is scarlet, a folder foam.

3, Therapeutic Method

Select above-mentioned medicament, each serving with 1 dose, every day early, middle and late respectively taking 1 time.Within 7 days, be a course for the treatment of, take continuously 3 courses for the treatment of.Period in a medicine diet is regular, discontinues the habit of smoking and drinking, and the pungent irritable food that waits of inedibility, diet is advisable with light.

4, efficacy assessment standard

Effective: clinical symptom disappearance after treatment, epistaxis recovery from illness, it is normal that patient's body constitution is recovered, and observes half a year without recidivist;

Take a turn for the better: clinical symptoms is obviously improved, and body constitution is progressively recovered;

Invalid: clinical partial symptoms disappears or without change, do not reach improvement standard person.

5, therapeutic outcome

In above-mentioned treatment, by Drug therapy Patients of Nasal Hemorrhage 200 examples of the present invention, effective 190 examples of result, obvious effective rate is 95%, 8 examples that take a turn for the better, and improvement rate is 4%, invalid 2 examples, total effective rate is 99%.

Claims (3)

1. a medicine for the treatment of epistaxis, is characterized in that: it is to be made up of the crude drug in following weight range:

Fructus Gardeniae 2-10 gram Herba Agrimoniae 10-20 gram Radix Ophiopogonis 5-15 gram

Nodus Nelumbinis Rhizomatis 5-10 gram of Rhizoma Imperatae 10-20 Rana nigromaculata bitterroot 10-15 gram

Radix Angelicae Sinensis 5-15 gram of Radix Rubiae 5-15 gram of Ramulus Cinnamomi 2-8 gram

Folium Artemisiae Argyi 4-9 gram of Flos Chrysanthemi 5-10 gram of Radix Rehmanniae 5-15 gram

5-15 gram of Radix Paeoniae Rubra 3-7 gram of Concha Ostreae 5-15 Keshan medicine

Mirabilitum crystallina 10-20 gram of Haematitum 10-15 gram of Radix Glycyrrhizae 5-15 gram

Colla Corii Asini 3-7 gram of Radix Scutellariae 5-15 gram of Arillus Longan 5-15 gram

Mel 10-15 gram.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

10 grams of 6 grams of Herba Agrimoniaes of Fructus Gardeniae 15 grams of Radix Ophiopogonis

12 grams of 8 grams of Rhizoma Imperataes of Nodus Nelumbinis Rhizomatis, 15 Rana nigromaculata bitterroots

5 grams of 10 grams of Ramulus Cinnamomi of 10 grams of Radix Rubiae of Radix Angelicae Sinensis

10 grams of 8 grams of Radix Rehmanniae of 7 grams of Flos Chrysanthemis of Folium Artemisiae Argyi

5 grams of 10 grams of Radix Paeoniae Rubra of Concha Ostreae 10 Keshan medicine

10 grams, 12 grams of Radix Glycyrrhizaes of 15 grams of Haematitums of Mirabilitum crystallina

10 grams of 10 grams of Arillus Longans of 5 grams of Radix Scutellariaes of Colla Corii Asini

12 grams of Mel.

3. according to the preparation method of medicine described in claim 1 or 2, it comprises the following steps:

(1) get the raw materials ready

(1) Fructus Gardeniae: get the Fructus Gardeniae of pulverizing, put in pot and fry with high heat to pitchy, take out, cool;

(2) Herba Agrimoniae: remove impurity undesirable root, clean, run through, cut off, dry;

(3) Radix Ophiopogonis: choose clean impurity, be soaked in water, pull out, pump the heart after running through, then clean and dry;

(4) Nodus Nelumbinis Rhizomatis: get clean Nodus Nelumbinis Rhizomatis and put in pot and fry and be black to outside, inside is strong yellow, slightly spills clear water, takes out, dry;

(5) Rhizoma Imperatae: choose clean impurity, clean, micro-profit, cutting, dries, the clean chip of winnowing with a dustpan;

(6) Herba Portulacae: choose clean impurity, remove undesirable root, slightly moisten with water, cutting is dried;

(7) Radix Angelicae Sinensis: choose decontamination, clean, moistening, slightly dries in the air when suitable to inside and outside humidity, and section is dried;

(8) Radix Rubiae: choose clean impurity, remove Lu Miao, clean, run through rear timely section, dry;

(9) Ramulus Cinnamomi: water slightly soaks, pulls out, and moistening, to thoroughly, is cut into slices, and dries, and sieves anti-dandruff;

(10) Folium Artemisiae Argyi: choose decontamination, destemming, sieve dedust bits;

(11) Flos Chrysanthemi: choose clean leaf stalk, anthocaulus and spare impurity;

(12) Radix Rehmanniae: get clean Radix Rehmanniae pornographic movie, put in pot with high heat or moderate heat heating, constantly stir-fry, fry and be coke black to surface, inner coke yellow or burnt brown;

(13) Concha Ostreae: clean, dry, pulverize use;

(14) Rhizoma Dioscoreae: choose clean impurity, be soaked in water to Rhizoma Dioscoreae central part soften for degree, pull out slightly and dry in the air, section dry or dry;

(15) Radix Paeoniae Rubra: get crude drug, remove impurity, big or small stepping, cleans, runs through, shave, and dry, sieve removes chip;

(16) Mirabilitum crystallina: get crude drug, remove impurity, cleaning, drying, break into fragment;

(17) Haematitum: get crude drug, remove impurity, cleaning, drying, break into fragment or be ground into coarse powder;

(18) Radix Glycyrrhizae: choose decontamination, clean, be soaked in water and, pull out thoroughly time to eighty per cant, run through section, airing;

(19) Colla Corii Asini: smash use to pieces;

(20) Radix Scutellariae: choose decontamination, remove residual stem, with cold water infiltrate or put in boiled water and slightly soak and pull out, section, dry;

(21) Arillus Longan: get crude drug, remove impurity;

(22) Mel: get pure Mel, temper with slow fire, filter skimming;

(2) preparation

The Fructus Gardeniae of described weight, Herba Agrimoniae, Radix Ophiopogonis, Nodus Nelumbinis Rhizomatis, Rhizoma Imperatae, Herba Portulacae, Radix Angelicae Sinensis, Radix Rubiae, Ramulus Cinnamomi, Folium Artemisiae Argyi, Flos Chrysanthemi, Radix Rehmanniae, Concha Ostreae, Rhizoma Dioscoreae, Radix Paeoniae Rubra, Mirabilitum crystallina, Haematitum, Radix Glycyrrhizae, Colla Corii Asini, Radix Scutellariae, Arillus Longan, Mel medicine are added to 6 times of water gagings to be soaked 60 minutes, intense fire decocts boiling 20 minutes, add again 3 times of water gagings and use again slow fire boiling 30 minutes, must take medicinal liquid, will take medicinal liquid and be equally divided into 4 doses.