CN103191319A - Medicine for treating epistaxis and preparation method thereof - Google Patents

Abstract

The invention discloses a medicine for treating epistaxis and a preparation method thereof. The medicine is prepared from cape jasmine, radix ophiopogonis, lalang grass rhizome, herba portulacae, roots of madder, liquorice, donkey-hide gelatin and the like according to a certain weight ratio. The medicine disclosed by the invention has the functions of warming channel and promoting lactation, clearing away heat and reducing fire, and cooling blood and stopping blooding, is good in curative effect and high in recovery rate in treatment of epistaxis, and fast becomes effective.

Description

A kind of medicine for the treatment of epistaxis and preparation method thereof

Technical field

The present invention relates to a kind of medicine for the treatment of epistaxis and preparation method thereof, belong to the field of Chinese medicines.

Background technology

Blood is called epistaxis from cleaning the street for nose.It is common a kind of disease.Contain partially mainly due to lung, stomach, liver-fire heat, the absurd row of forcing blood, so that blood oozing from the body openings or subcuta neous tissue cleans the street, and flows out from the nostril to form epistaxis, minority also arranged by person due to deficiency of kidney-essence or the deficient QI failing to control.Epistaxis also is called nosebleed.The epistaxis amount is called serious epistaxis or profuse nose-bleed again for a long time.Just commonly go out nose bleeding.Epistaxis also claims epistaxis rather common, generally can be divided into two classes, by the epistaxis due to the nose local cause with as the symptomatic epistaxis of the topical manifestations of systemic disease.Especially more common with symptomatic epistaxis, its sickness rate is about the former 2 times.The epistaxis that local factor causes mostly is one-sided property greatly, and hemorrhage mostly occurring is imbued with the position of blood capillary prerolandic artery Rolando in the nasal septum front portion.Herein tissue elasticity lower, when being stimulated (as digging nose, drying, dust etc.), the mucosa blood vessel breaks easily, causes hemorrhage.Symptomatic epistaxis is found in blood vessel and kidney disease (as blood vessel wall infringement, uremia etc.).Hemorrhagic diathesis and some infectious disease (as influenza, measles, diphtheria, typhoid fever etc.).Hereditary hemorrhagic peripheral vessel di patient's the congenital weakness of blood vessel wall, there have expansion then can break slightly to be hemorrhage.Western medicine can't effectively be treated epistaxis at present, and certain side effect is arranged, and therefore, there is great demand in people to the Chinese medicine of effective treatment epistaxis.

Summary of the invention

The inventor has found the medicine of effective treatment epistaxis finally, thereby has finished the present invention according to the research of theory of Chinese medical science and clinical repeatedly test and checking.

Purpose of the present invention just provides a kind of composition of medicine that can treat epistaxis.

Another object of the present invention has just provided the preparation method of this composition of medicine.

Medicine of the present invention selects for use Fructus Gardeniae, Herba Agrimoniae, Radix Ophiopogonis, Nodus Nelumbinis Rhizomatis, Rhizoma Imperatae, Herba Portulacae, Radix Angelicae Sinensis, Radix Rubiae, Ramulus Cinnamomi, Folium Artemisiae Argyi, Flos Chrysanthemi, Radix Rehmanniae, Concha Ostreae, Rhizoma Dioscoreae, Radix Paeoniae Rubra, Mirabilitum crystallina, Haematitum, Radix Glycyrrhizae, Colla Corii Asini, Radix Scutellariae, Arillus Longan, Mel medicine to make up, make each efficacy of drugs produce synergism these drug regimens, thereby can treat the recurrence of epistaxis fast.Wherein select for use Fructus Gardeniae to be because its nature and flavor hardship is cold, go into the heart, liver, lung, stomach warp, heat clearing away is arranged, pathogenic fire purging, the function of removing heat from blood is controlled the calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea is quenched one's thirst, conjunctival congestion, pharyngalgia is spitted blood, epistaxis, dysentery, hematuria, pathopyretic ulcer is sprained and is swollen and ache.Select for use Herba Agrimoniae to be because its nature and flavor toil is flat, go into lung, liver, spleen channel, hemostasis is arranged, the function of stomach invigorating is controlled spitting of blood, spits blood, and hematuria is had blood in stool, dysentery, and bleeding not during menses, impairment caused by overstrain is taken off power, carbuncle, traumatic injury, wound hemorrhage.Select for use be Radix Ophiopogonis because its property sweet and slightly bitter taste is cold, go into lung, stomach, heart channel, nourishing YIN and moistening the lung is arranged, the relieving restlessness that clears away heart-fire, the function of reinforcing stomach reg fluid is controlled dryness of the lung dry cough, spits blood, spitting of blood, consumptive lung disease, lung abscess, the asthenia dysphoria with smothery sensation, clear thirsty, hinder in calentura Tianjin, dry mouth and throat, constipation.Select for use Nodus Nelumbinis Rhizomatis to be because its property sweet-puckery flavor is flat, few the moon of starting with, the foot sun is bright, and JUE YIN meridian has hemostasis, and the function of dissipating blood stasis is controlled hemoptysis, spits blood, epistaxis, hematuria is had blood in stool, dysentery, metrorrhagia.It is sweet because of its nature and flavor, cold selecting Rhizoma Imperatae for use, goes into lung, stomach, small intestine meridian, and removing heat from blood is arranged, hemostasis, and heat clearing away, the function of diuresis is controlled the calentura excessive thirst, spits blood epistaxis, lung-heat dyspnea with rapid respiration, gastric heat hiccup, gonorrhea, dysuria, edema, jaundice.Select for use Herba Portulacae to be because its nature and flavor acid is cold, go into large intestine, liver, spleen channel, heat-clearing and toxic substances removing is arranged, the function of the blood detumescence of loosing is controlled the hematodiarrhoea pus and blood, pyretic stranguria, stranguria with blood, leukorrhagia, carbuncle malignant boil, erysipelas, scrofula.Selecting Radix Angelicae Sinensis for use is that temperature is gone into the heart, liver, spleen channel, and benefiting blood and regulating blood circulation is arranged, menstruction regulating and pain relieving, the function of moisturizing laxation because of the sweet suffering of its nature and flavor, control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty are just, and be heavy after the bloody dysentery, ulcer sores, incised wound, injury from falling down.Select for use Radix Rubiae to be because its nature and flavor hardship is cold, go into the heart, Liver Channel, the promoting the circulation of blood hemostasis is arranged, dredge the meridian passage, eliminating phlegm and stopping cough is controlled haematemesis, epistaxis, hematuria is had blood in stool, metrorrhagia, amenorrhea, rheumatic arthralgia, traumatic injury, the stasis of blood stagnates and swells and ache jaundice, property tracheitis.Selecting Ramulus Cinnamomi for use is that temperature is gone into bladder, the heart, lung meridian, and the diaphoresis expelling pathogenic factors from muscles is arranged because of its property acrid-sweet flavor, and the function of warming the meridian and promoting blood circulation is controlled exterior syndrome due to wind-cold, shoulder back of the body podomere ache, thoracic obstruction phlegm retention, amenorrhea and mass in the abdomen.Folium Artemisiae Argyi is because of its nature and flavor toil, temperature.Go into spleen, liver, kidney channel.The blood of regulating the flow of vital energy is by cold-damp; Warming the meridian, hemostasis, antiabortive.Control trusted subordinate's cold type of pain, the convulsion of having loose bowels, chronic dysentery is told nosebleed, hematochezia, menoxenia, metrorrhagia, leukorrhagia, frequent fetal movement, carbuncle and ulcer, scabies.Selecting Flos Chrysanthemi for use is that lung is gone in cold because of its nature and flavor sweetness and bitterness, and Liver Channel has dispelling wind, and the heat that disappears makes eye bright, and the function of detoxifcation is controlled headache, and is dizzy, conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, toxic swelling.Select for use Radix Rehmanniae to be because its nature and flavor are sweet, cold, GUIXIN, liver, kidney channel have clearing away heat and cooling blood, yin nourishing, and the function of promoting the production of body fluid is controlled the calentura excessive thirst, yin asthenia generating intrinsic heat, the hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis is sent out the speckle dermexanthesis.Select for use Concha Ostreae to be because its nature and flavor are salty and bitter, liver, kidney channel are gone in cold, and yin fluid astringing is arranged, YANG hyperactivity suppressing, and hidroschesis, arresting seminal emission reduces phlegm, the function of softening the hard mass, Zhi Jing Epilepsy, dizzy, spontaneous perspiration, night sweat, seminal emission, stranguria with turbid discharge, metrorrhagia, leukorrhagia, scrofula, goiter.Select for use Rhizoma Dioscoreae to be because its nature and flavor are sweet, flat, go into lung, spleen, kidney channel, spleen invigorating is arranged, tonifying the lung is reinforced the kidney, and the function that benefit is smart is controlled diarrhea due to hypofunction of the spleen, chronic dysentery, cough due to consumptive disease is quenched one's thirst, seminal emission, leukorrhagia, frequent micturition.Select for use Radix Paeoniae Rubra to be because its nature and flavor hardship is slightly cold, return Liver Channel, clearing away heat and cooling blood is arranged, the function of eliminating stasis to stop pain is controlled warm poison and is gone mad, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea ， Epilepsy abdominal mass stomachache, injury from falling down, carbuncle skin infection.Select for use Mirabilitum crystallina to be because its nature and flavor suffering is salty, cold, go into the heart, stomach, kidney channel, resolving heat and reducing pathogenic fire is arranged, sharp key, the function of detumescence, row calentura when controlling, long-pending hot excessive thirst is vomited and diarrhoea, edema, urine retention, bleeding from the gum, erysipelas is scalded.Select for use Haematitum to be because its nature and flavor hardship, sweet is slightly cold, return liver, stomach, heart channel, suppressing the hyperactive liver and subsiding YANG is arranged, the important city sending down the abnormal ascending QI, the function of cooling blood for hemostasis, it is preceding dizzy to control head, and cardiopalmus is demented, infantile convulsion, vomiting, eructation, cough and asthma is spitted blood, epistaxis, metrorrhagia is had blood in stool, hematuria.Select for use Radix Glycyrrhizae to be because its nature and flavor are sweet flat, go into spleen, stomach, lung meridian, have and middle emergency, lung moistening, detoxifcation, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach, lack of appetite, stomachache loose stool, the overstrain heating, consumptive lung disease cough, cardiopalmus, frightened carbuncle is given birth to controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores is separated poison of drug and alimentary toxicosis.Select for use Colla Corii Asini to be because its nature and flavor are sweet flat, go into lung, liver, kidney channel, nourishing YIN and supplementing blood is arranged, antiabortive function is controlled blood deficiency, and cough due to consumptive disease, is had blood in stool at haematemesis, epistaxis, menoxenia, and metrorrhagia is controlled leakage.Select for use Radix Scutellariae to be because its nature and flavor bitter cold is gone into cardiopulmonary, gallbladder, large intestine channel, the removing the relative excess fire is arranged, except damp and hot, the function of arresting bleeding and miscarriage prevention is controlled the high fever excessive thirst, the cough due to lung-heat.Select for use Arillus Longan to be because its nature and flavor are sweet, temperature is gone into the heart, spleen channel, and heart-spleen boosting is arranged, fill blood, and the function of calming the nerves, it is thin and weak to control virtual work, and insomnia is forgetful, palpitation with fear, severe palpitation.Select for use Mel to be because its nature and flavor are sweet, flat, go into lung, spleen, large intestine channel, invigorating middle warmer is arranged, moisturize, pain relieving, the function of detoxifcation is controlled the xeropulmonary cough, the dryness of the intestine constipation, gastralgia, nasal sinusitis, aphtha, the burning hot wound of soup is separated the Aconitum carmichjaelii Debx. poison.

The specific embodiment

The drug dose of component of the present invention also is that the inventor draws through groping in a large number to sum up, and the consumption of each component all has better curative effect in the following weight scope

Fructus Gardeniae 2-10 gram Herba Agrimoniae 10-20 gram 5-15 Radix Ophiopogonis gram

Nodus Nelumbinis Rhizomatis 5-10 gram Rhizoma Imperatae 10-20 Rana nigromaculata bitterroot 10-15 gram

Radix Angelicae Sinensis 5-15 gram Radix Rubiae 5-15 gram Ramulus Cinnamomi 2-8 gram

Folium Artemisiae Argyi 4-9 gram Flos Chrysanthemi 5-10 gram Radix Rehmanniae 5-15 gram

Concha Ostreae 5-15 Keshan medicine 5-15 gram Radix Paeoniae Rubra 3-7 gram

Mirabilitum crystallina 10-20 gram Haematitum 10-15 gram Radix Glycyrrhizae 5-15 gram

Colla Corii Asini 3-7 gram Radix Scutellariae 5-15 gram Arillus Longan 5-15 gram

Mel 10-15 gram

Wherein, be preferably

Fructus Gardeniae 6 gram Herba Agrimoniaes 15 gram grams Radix Ophiopogonis 10

Nodus Nelumbinis Rhizomatis 8 gram Rhizoma Imperataes 15 Rana nigromaculata bitterroots 12 grams

Radix Angelicae Sinensis 10 gram Radix Rubiae 10 gram Ramulus Cinnamomi 5 grams

Folium Artemisiae Argyi 7 gram Flos Chrysanthemis 8 gram Radix Rehmanniae 10 grams

Concha Ostreae 10 Keshan medicines 10 gram Radix Paeoniae Rubra 5 grams

Mirabilitum crystallina 15 gram Haematitums 12 gram Radix Glycyrrhizaes 10 grams

Colla Corii Asini 5 gram Radix Scutellariaes 10 gram Arillus Longans 10 grams

Mel 12 grams

The preparation method of medicine of the present invention is as follows

One, gets the raw materials ready

1, Fructus Gardeniae: get the Fructus Gardeniae of pulverizing, put in the pot and fry with high heat to pitchy, take out, cool;

2, Herba Agrimoniae: remove the impurity undesirable root, clean, run through, cut off, dry;

3, Radix Ophiopogonis: choose clean impurity, be soaked in water, pull out, take out the heart after running through, clean again and dry;

4, Nodus Nelumbinis Rhizomatis: get clean Nodus Nelumbinis Rhizomatis and put to fry in the pot and be black to the outside, inside is strong yellow, spills clear water slightly, takes out drying;

5, Rhizoma Imperatae: choose clean impurity, clean, little profit, cutting is dried, the clean chip of winnowing with a dustpan;

6, Herba Portulacae: choose clean impurity, remove undesirable root, moisten slightly with water, cutting is dried;

7, Radix Angelicae Sinensis: choose decontamination, clean, moistening dries in the air when suitable to inside and outside humidity slightly, and section is dried;

8, Radix Rubiae: choose clean impurity, remove Lu Miao, clean, run through back section in time, dry;

9, Ramulus Cinnamomi: water soaks slightly, pulls out, and moistening is to saturating, and section is dried, and sieves anti-dandruff;

10, Folium Artemisiae Argyi: choose decontamination, destemming, sieve dedust bits;

11, Flos Chrysanthemi: choose clean leaf stalk, anthocaulus and spare impurity;

12, Radix Rehmanniae: get clean Radix Rehmanniae pornographic movie, put in the pot with high heat or the moderate heat heating, constantly stir-fry, fry and be coke black to the surface, inner coke yellow or burnt brown;

13, Concha Ostreae: clean, dry, pulverize usefulness;

14, Rhizoma Dioscoreae: choose clean impurity, be soaked in water and pull out and dry in the air slightly for degree to the Rhizoma Dioscoreae central part is softening, section is dried or is dried;

15, Radix Paeoniae Rubra: get crude drug, remove impurity, big or small stepping is cleaned, runs through, and shave, drying, sieve removes chip;

16, Mirabilitum crystallina: get crude drug, remove impurity, cleaning, drying break into fragment;

17, Haematitum: get crude drug, remove impurity, cleaning, drying break into fragment or grind into coarse powder;

18, Radix Glycyrrhizae: choose decontamination, clean, be soaked in water when saturating to eighty per cant, pull out, run through section, airing;

19, Colla Corii Asini: smash usefulness to pieces;

20, Radix Scutellariae: choose decontamination, remove residual stem, soak into or put to soak slightly in the boiled water and pull out with cold water, section is dried;

21, Arillus Longan: get crude drug, remove impurity;

22, Mel: get pure Mel, temper with slow fire, filter skimming.

Two, preparation

Fructus Gardeniae, Herba Agrimoniae, Radix Ophiopogonis, Nodus Nelumbinis Rhizomatis, Rhizoma Imperatae, Herba Portulacae, Radix Angelicae Sinensis, Radix Rubiae, Ramulus Cinnamomi, Folium Artemisiae Argyi, Flos Chrysanthemi, Radix Rehmanniae, Concha Ostreae, Rhizoma Dioscoreae, Radix Paeoniae Rubra, Mirabilitum crystallina, Haematitum, Radix Glycyrrhizae, Colla Corii Asini, Radix Scutellariae, Arillus Longan, the Mel medicine of described weight are added 6 times of water gagings immersions 60 minutes, intense fire decocts boiling 20 minutes, add 3 times of water gagings again and used slow fire boiling again 30 minutes, namely get and take medicinal liquid, will take medicinal liquid and be equally divided into 4 doses and get final product.

Medicine of the present invention has the function of warming the meridian and promoting blood circulation, clearing away heat-fire, cooling blood for hemostasis.Treatment epistaxis instant effect, short treating period do not recur the cure rate height.

Below further set forth the beneficial effect of medicine of the present invention by testing example, these tests comprise that the animal toxicity test of medicine of the present invention and clinical observation test.

The animal toxicity test report of [test example 1] medicine of the present invention

Get 20 of rabbit, the male and female dual-purpose, body weight 2.0-2.5kg divides two groups, and 10 every group, wherein one group is the overdose test group, and another group is the normal amount test group.The super quantity group is 30ml/kg, and normal amount is 15ml/kg, and administering mode is the administration by gavage administration, serve on 7 days every day 2 times, observes administration reaction every day, and the result shows that two groups of rabbit activities, diet are normal, and medicine does not have bad toxic and side effects.

The clinical observation material of [test example 2] medicine of the present invention

1, physical data

Accept out-patient's 200 examples for medical treatment.

2, diagnostic criteria

(1) blood flows out from the nostril, can be diagnosed as epistaxis.Epistaxis the lighter only is with the blood streak in the tears; Severe patient, blood is gushed out from mouth and nose.

(2) epistaxis person very, blood can overflow to go out from mouth, or is swallowed moments later vomiting because of a large amount of blood.Therefore, epistaxis should be differentiated mutually with haematemesis, spitting of blood.Spitting of blood is the injured caused disease of lung network, and its blood must go out through the air flue cough, mixture of phlegm and blood, or sputum mixed with blood silk, or pure blood is scarlet, a folder foam.

3, Therapeutic Method

Select above-mentioned medicament for use, take 1 dose at every turn, every day early, middle and late respectively taking 1 time.7 days is a course for the treatment of, takes 3 courses for the treatment of continuously.The period in a medicine diet is regular, discontinues the habit of smoking and drinking, and the pungent irritable food that waits of inedibility, diet is advisable with light.

4, efficacy assessment standard

Produce effects: treatment back clinical symptom disappearance, the epistaxis recovery from illness, it is normal that patient's body constitution is recovered, and observes and do not have the recidivist half a year;

Take a turn for the better: clinical symptoms is obviously improved, and body constitution is progressively recovered;

Invalid: clinical partial symptoms disappears or does not have change, does not reach improvement standard person.

5, therapeutic outcome

In above-mentioned treatment, with Drug therapy epistaxis patient 200 examples of the present invention, produce effects 190 examples as a result, obvious effective rate is 95%, 8 examples that take a turn for the better, improvement rate is 4%, invalid 2 examples, total effective rate is 99%.

Claims (3)

1. medicine for the treatment of epistaxis, it is characterized in that: it is to be made by the crude drug in the following weight range:

Fructus Gardeniae 2-10 gram Herba Agrimoniae 10-20 gram 5-15 Radix Ophiopogonis gram

Nodus Nelumbinis Rhizomatis 5-10 gram Rhizoma Imperatae 10-20 Rana nigromaculata bitterroot 10-15 gram

Radix Angelicae Sinensis 5-15 gram Radix Rubiae 5-15 gram Ramulus Cinnamomi 2-8 gram

Folium Artemisiae Argyi 4-9 gram Flos Chrysanthemi 5-10 gram Radix Rehmanniae 5-15 gram

Concha Ostreae 5-15 Keshan medicine 5-15 gram Radix Paeoniae Rubra 3-7 gram

Mirabilitum crystallina 10-20 gram Haematitum 10-15 gram Radix Glycyrrhizae 5-15 gram

Colla Corii Asini 3-7 gram Radix Scutellariae 5-15 gram Arillus Longan 5-15 gram

Mel 10-15 gram.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

Fructus Gardeniae 6 gram Herba Agrimoniaes 15 gram grams Radix Ophiopogonis 10

Nodus Nelumbinis Rhizomatis 8 gram Rhizoma Imperataes 15 Rana nigromaculata bitterroots 12 grams

Radix Angelicae Sinensis 10 gram Radix Rubiae 10 gram Ramulus Cinnamomi 5 grams

Folium Artemisiae Argyi 7 gram Flos Chrysanthemis 8 gram Radix Rehmanniae 10 grams

Concha Ostreae 10 Keshan medicines 10 gram Radix Paeoniae Rubra 5 grams

Mirabilitum crystallina 15 gram Haematitums 12 gram Radix Glycyrrhizaes 10 grams

Colla Corii Asini 5 gram Radix Scutellariaes 10 gram Arillus Longans 10 grams

Mel 12 grams.

3. according to the preparation method of claim 1 or 2 described medicines, it comprises the following steps:

(1) gets the raw materials ready

(1) Fructus Gardeniae: get the Fructus Gardeniae of pulverizing, put in the pot and fry with high heat to pitchy, take out, cool;

(2) Herba Agrimoniae: remove the impurity undesirable root, clean, run through, cut off, dry;

(3) Radix Ophiopogonis: choose clean impurity, be soaked in water, pull out, take out the heart after running through, clean again and dry;

(4) Nodus Nelumbinis Rhizomatis: get clean Nodus Nelumbinis Rhizomatis and put to fry in the pot and be black to the outside, inside is strong yellow, spills clear water slightly, takes out drying;

(5) Rhizoma Imperatae: choose clean impurity, clean, little profit, cutting is dried, the clean chip of winnowing with a dustpan;

(6) Herba Portulacae: choose clean impurity, remove undesirable root, moisten slightly with water, cutting is dried;

(7) Radix Angelicae Sinensis: choose decontamination, clean, moistening dries in the air when suitable to inside and outside humidity slightly, and section is dried;

(8) Radix Rubiae: choose clean impurity, remove Lu Miao, clean, run through back section in time, dry;

(9) Ramulus Cinnamomi: water soaks slightly, pulls out, and moistening is to saturating, and section is dried, and sieves anti-dandruff;

(10) Folium Artemisiae Argyi: choose decontamination, destemming, sieve dedust bits;

(11) Flos Chrysanthemi: choose clean leaf stalk, anthocaulus and spare impurity;

(12) Radix Rehmanniae: get clean Radix Rehmanniae pornographic movie, put in the pot with high heat or the moderate heat heating, constantly stir-fry, fry and be coke black to the surface, inner coke yellow or burnt brown;

(13) Concha Ostreae: clean, dry, pulverize usefulness;

(14) Rhizoma Dioscoreae: choose clean impurity, be soaked in water and pull out and dry in the air slightly for degree to the Rhizoma Dioscoreae central part is softening, section is dried or is dried;

(15) Radix Paeoniae Rubra: get crude drug, remove impurity, big or small stepping is cleaned, runs through, and shave, drying, sieve removes chip;

(16) Mirabilitum crystallina: get crude drug, remove impurity, cleaning, drying break into fragment;

(17) Haematitum: get crude drug, remove impurity, cleaning, drying break into fragment or grind into coarse powder;

(18) Radix Glycyrrhizae: choose decontamination, clean, be soaked in water when saturating to eighty per cant, pull out, run through section, airing;

(19) Colla Corii Asini: smash usefulness to pieces;

(20) Radix Scutellariae: choose decontamination, remove residual stem, soak into or put to soak slightly in the boiled water and pull out with cold water, section is dried;

(21) Arillus Longan: get crude drug, remove impurity;

(22) Mel: get pure Mel, temper with slow fire, filter skimming;

(2) preparation

Fructus Gardeniae, Herba Agrimoniae, Radix Ophiopogonis, Nodus Nelumbinis Rhizomatis, Rhizoma Imperatae, Herba Portulacae, Radix Angelicae Sinensis, Radix Rubiae, Ramulus Cinnamomi, Folium Artemisiae Argyi, Flos Chrysanthemi, Radix Rehmanniae, Concha Ostreae, Rhizoma Dioscoreae, Radix Paeoniae Rubra, Mirabilitum crystallina, Haematitum, Radix Glycyrrhizae, Colla Corii Asini, Radix Scutellariae, Arillus Longan, the Mel medicine of described weight are added 6 times of water gagings immersions 60 minutes, intense fire decocts boiling 20 minutes, add 3 times of water gagings again and used slow fire boiling again 30 minutes, namely get and take medicinal liquid, will take medicinal liquid and be equally divided into 4 doses and get final product.